{"title":"Benign migratory glossitis.","authors":"Jimena Pérez-Rubio, Ana Laura Ramírez-Terán","doi":"10.3949/ccjm.92a.24074","DOIUrl":"https://doi.org/10.3949/ccjm.92a.24074","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 10","pages":"591-592"},"PeriodicalIF":4.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nearly a century of using glucocorticoids in patients with active infection.","authors":"Adam J Brown","doi":"10.3949/ccjm.92a.25074","DOIUrl":"https://doi.org/10.3949/ccjm.92a.25074","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 10","pages":"605-608"},"PeriodicalIF":4.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cardiovascular disease remains a leading cause of morbidity and mortality worldwide. Though inflammation plays an important role in atherogenesis, treatments directly targeting inflammatory pathways have had mixed results on improving clinical outcomes. Low-dose colchicine has been studied recently for the management of atherosclerotic cardiovascular disease. We explore the history of colchicine as an anti-inflammatory agent, review clinical trial data of colchicine for atherosclerotic cardiovascular disease, and discuss practical considerations for adding low-dose colchicine in this setting.
{"title":"Low-dose colchicine for management of coronary artery disease.","authors":"Abhayjit Singh, Vikas Sunder, Leslie Cho","doi":"10.3949/ccjm.92a.25005","DOIUrl":"https://doi.org/10.3949/ccjm.92a.25005","url":null,"abstract":"<p><p>Cardiovascular disease remains a leading cause of morbidity and mortality worldwide. Though inflammation plays an important role in atherogenesis, treatments directly targeting inflammatory pathways have had mixed results on improving clinical outcomes. Low-dose colchicine has been studied recently for the management of atherosclerotic cardiovascular disease. We explore the history of colchicine as an anti-inflammatory agent, review clinical trial data of colchicine for atherosclerotic cardiovascular disease, and discuss practical considerations for adding low-dose colchicine in this setting.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 10","pages":"609-618"},"PeriodicalIF":4.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Glucagon-like peptide-1 receptor agonists and pancreatitis: A reconcilable divorce.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 10","pages":"593"},"PeriodicalIF":4.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alejandro Chapa-Rodriguez, Tark Abou-Elmagd, Cody O'Rear, Shraddha Narechania
{"title":"Do patients with severe community-acquired bacterial pneumonia benefit from systemic corticosteroids?","authors":"Alejandro Chapa-Rodriguez, Tark Abou-Elmagd, Cody O'Rear, Shraddha Narechania","doi":"10.3949/ccjm.92a.25023","DOIUrl":"https://doi.org/10.3949/ccjm.92a.25023","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 10","pages":"600-604"},"PeriodicalIF":4.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Should glucagon-like peptide 1 receptor agonists be withheld during the preoperative period?","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 10","pages":"593"},"PeriodicalIF":4.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Collaborative musculoskeletal care: The role for chiropractors.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 10","pages":"593"},"PeriodicalIF":4.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In July 2023, the US Food and Drug Administration approved the first over-the-counter (OTC) daily oral contraceptive pill, Opill (norgestrel). The widespread availability of a daily oral contraceptive pill without a prescription is a major advancement in reproductive health and improves access to safe, effective, affordable contraception. This article outlines the types of OTC contraceptives currently available in the United States, with a focus on OTC norgestrel and its implications for increased accessibility to reproductive healthcare.
{"title":"An overview of over-the-counter contraceptives: Spotlight on daily oral norgestrel.","authors":"Rujuta Takalkar, Andrea Lorenzo, Suneela Vegunta","doi":"10.3949/ccjm.92a.24108","DOIUrl":"10.3949/ccjm.92a.24108","url":null,"abstract":"<p><p>In July 2023, the US Food and Drug Administration approved the first over-the-counter (OTC) daily oral contraceptive pill, Opill (norgestrel). The widespread availability of a daily oral contraceptive pill without a prescription is a major advancement in reproductive health and improves access to safe, effective, affordable contraception. This article outlines the types of OTC contraceptives currently available in the United States, with a focus on OTC norgestrel and its implications for increased accessibility to reproductive healthcare.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 9","pages":"572-576"},"PeriodicalIF":4.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144944994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joseph Hajj, Allaa Almoushref, Georges Nakhoul, George Thomas
{"title":"What is the role of cystatin C in estimating glomerular filtration rate and guiding medication dosing?","authors":"Joseph Hajj, Allaa Almoushref, Georges Nakhoul, George Thomas","doi":"10.3949/ccjm.92a.25036","DOIUrl":"https://doi.org/10.3949/ccjm.92a.25036","url":null,"abstract":"","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 9","pages":"546-549"},"PeriodicalIF":4.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The definition of acute respiratory distress syndrome (ARDS) has been updated several times since the syndrome was first described in 1967. The aim of the initial definition was to better study this disease and standardize its care. Each iteration has brought its own set of nuances and challenges. In 2024, a new global definition of ARDS was proposed. This review highlights the evolution of ARDS definitions over the years and discusses the key components of the new proposed global definition.
{"title":"Acute respiratory distress syndrome: Why a definition matters.","authors":"Christine Girard, Divyajot Sadana, Shewit Giovanni, Heather Torbic, Abhijit Duggal","doi":"10.3949/ccjm.92a.24115","DOIUrl":"10.3949/ccjm.92a.24115","url":null,"abstract":"<p><p>The definition of acute respiratory distress syndrome (ARDS) has been updated several times since the syndrome was first described in 1967. The aim of the initial definition was to better study this disease and standardize its care. Each iteration has brought its own set of nuances and challenges. In 2024, a new global definition of ARDS was proposed. This review highlights the evolution of ARDS definitions over the years and discusses the key components of the new proposed global definition.</p>","PeriodicalId":10245,"journal":{"name":"Cleveland Clinic Journal of Medicine","volume":"92 9","pages":"565-571"},"PeriodicalIF":4.1,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}