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Efficacy assessment of an intramammary formulation based on soluble polypyrrole in cows with experimentally induced mastitis 以可溶性聚吡咯为基础的乳内制剂对实验性乳腺炎奶牛的疗效评价
IF 0.8 4区 农林科学 Q3 AGRONOMY Pub Date : 2023-02-13 DOI: 10.1590/0103-8478cr20220047
Ana Paula de Faria Alves, Marcos Pinheiro do Amaral, D. Silva, Renata de Faria Silva Souza, Sílvio Alan Gonçalves Bomfim Reis, F. J. D. Silva Júnior, H. P. Oliveira, R. M. Peixoto, M. Costa
RESUMO: Considerando a necessidade de terapias alternativas para a mastite bovina, uma inflamação, normalmente de causa infecciosa, de alta prevalência e de alto impacto econômico nas fazendas leiteiras, avaliou-se a eficácia antimicrobiana, in vivo, de uma formulação intramamária à base de polipirrol (PPy) solúvel, um polímero condutor promissor para aplicações biomédicas, especialmente como potente antibacteriano. Neste ensaio, quartos mamários de vacas holandesas sadias (n = 8) foram inoculados com Staphylococcus aureus e tratados, por via intramamária, com formulação experimental à base de PPy solúvel (5%) e com formulação comercial à base de sulfato de gentamicina. O efeito desses tratamentos foi avaliado com a realização de lactoculturas, da Contagem Bacteriana Total (TBC), da Contagem de Células Somáticas (SCC) e da análise da composição do leite das amostras obtidas de quartos mamários, em sete momentos experimentais. Avaliação hematológica dos animais também foi realizada. A aplicação intramamária de três doses da formulação experimental à base de PPy solúvel resultou em maiores log/mL da TBC e da SCC quando comparadas ao grupo controle positivo e ao grupo que recebeu sulfato de gentamicina. A administração da formulação experimental não induziu alterações na composição do leite e nos parâmetros hematológicos. Alguns fatores farmacocinéticos e farmacodinâmicos do PPy solúvel podem ser atribuídos a ineficácia antimicrobiana da pomada experimental. Outras pesquisas devem ser realizados em prol do desenvolvimento de formulações que permitam a atuação antibacteriana do PPy solúvel no ambiente intramamário de vacas leiteiras.
空:考虑的替代疗法的必要性牛乳房炎,炎症,通常的高患病率和坏死,高牛奶农场经济影响评估的体内抗菌功效,乳房内的基地配方的可溶性polipirrol (PPy),一种很有前景的生物医学应用程序,尤其是导电聚合物作为强大的抗菌。在本试验中,健康荷斯坦奶牛(n = 8)的第四个乳房接种金黄色葡萄球菌,并在乳内注射以可溶性PPy(5%)为基础的实验配方和以硫酸庆大霉素为基础的商业配方。在7个实验时刻,通过乳腺培养、细菌总数(TBC)、体细胞计数(SCC)和牛奶成分分析来评估这些治疗的效果。对动物进行血液学评估。与阳性对照组和硫酸庆大霉素组相比,三剂以可溶性PPy为基础的实验配方的乳内应用导致TBC和SCC的log/mL增加。实验配方的使用没有引起牛奶成分和血液学参数的变化。可溶性PPy的一些药代动力学和药效学因素可归因于实验软膏的抗菌无效。为了开发能使可溶性PPy在奶牛乳内环境中发挥抗菌作用的配方,还需要进行进一步的研究。
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引用次数: 0
Agronomic performance of Humuluslupulus L. varieties cultivated in organic and conventional systems in São Paulo center-west, Brazil 巴西圣保罗中西部有机栽培和常规栽培下葎草品种的农艺性能
IF 0.8 4区 农林科学 Q3 AGRONOMY Pub Date : 2023-02-10 DOI: 10.1590/0103-8478cr20210704
G. Fortuna, J. Gomes, Olivia Pak Campos, Caio Scardini Neves, F. Bonfim
ABSTRACT: Hop is a multifunctional specie; however, a large part of its production is destined for the beer market. In Brazil, all hop demand is imported, which has aroused interest in national production. Genetic material and cultivation systems can influence hops production. Thus, this study evaluated morphological and productive performance of hop varieties grown under organic and conventional management in the central-west region of São Paulo, Brazil. The hop yard was installed in the experimental area of the FCA/UNESP (São Paulo State University, School of Agriculture) - Botucatu, in November 2018, the data were collected in second year of production. A randomized block design was adopted, in 2 x 5 Split-Plot, being the main factor: cultivation systems (organic and conventional), and secondary factor: hop varieties (Columbus, Chinook, Nugget, Cascade, and HallertauMittelfrüeh), with four blocks and four plants per plot. Crop-specific morphological and productive parameters were evaluated. The results showed no significant influence of cultivation systems in morphological parameters. Regarding the varieties, Chinook, Cascade, and Nugget stand out for cone length. Columbus, Chinook and Cascade showed higher yields when grown in organic system, obtaining 1100.66, 1088.27 and 940.40 g of cones per plant, respectively. While, HallertauMittelfrüeh variety was the least productive in both systems, in organic system with 160.50 g per plant production, and 267.84 g per plant in conventional system, and, also showing lower cycle compared to the others.
摘要:啤酒花是一种多功能植物;然而,它的大部分产品都是面向啤酒市场的。在巴西,所有的啤酒花需求都是进口的,这引起了人们对国内生产的兴趣。遗传物质和栽培系统可以影响啤酒花的生产。因此,本研究评估了在巴西圣保罗中西部地区有机和常规管理下种植的啤酒花品种的形态和生产性能。该啤酒花庭院于2018年11月安装在FCA/UNESP (圣保罗州立大学农学院)- boucatu的实验区,数据是在生产的第二年收集的。采用随机区组设计,在2 × 5的分裂地块中,主要因素是:种植系统(有机和常规),次要因素是:啤酒花品种(哥伦布,奇努克,纽金特,Cascade和hallertaumittelfr),每个地块有四个区组和四个植物。评估了作物特有的形态和生产参数。结果表明,栽培制度对形态参数的影响不显著。关于品种,奇努克,喀斯喀特和努格特脱颖而出的锥体长度。哥伦布、奇努克和喀斯喀特在有机体系中产量较高,单株球果产量分别为11000.66、1088.27和940.40 g。而hallertaumittelfr品种在有机体系中单株产量为160.50 g,在常规体系中单株产量为267.84 g,在有机体系中单株产量最低,且周期较低。
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引用次数: 0
Spatial and temporal distribution and bioinsecticides control of olive leaf moth in an olive orchard in Southwest of Paraná, Brazil 巴西帕拉纳<e:1>西南部橄榄园橄榄叶蛾时空分布及生物杀虫剂防治
IF 0.8 4区 农林科学 Q3 AGRONOMY Pub Date : 2023-02-10 DOI: 10.1590/0103-8478cr20220008
Gilberto C C Carmona, G. Andrade, I. Citadin, R. H. Pertille, J. R. R. Campos, A. Rohr, M. A. Danner
ABSTRACT: We verified the spatial and temporal distribution of the olive leaf moth (Palpita forficifera Munroe, 1959) in a new potential region for olive cultivation and evaluated the bioinsecticides effectiveness to control this pest. The experimental orchard composed by Koroneiki and Arbequina cultivars was planted in Pato Branco, Southwest region of Paraná, Brazil. In the field, larvae counts were performed weekly on 25 plants of each cultivar, for 12 months, to verify the spatial and temporal distribution. Furthermore, in laboratory conditions, second instar larvae of P. forficifera were fed with olive leaves treated with Azadirachta indica oil, Bacillus thuringiensis, Metarhizium anisopliae and Beauveria bassiana, and the effectiveness in the larvae mortality was used to compare four bioinsecticides and control. The P. forficifera larvae occurred mainly during the three summer months, had a host preference for the ‘Arbequina’ (68.9% of total larvae) and occurred at random distribution patterns throughout the orchard. The A. indica oil and B. thuringiensis both caused almost 100% larvae mortality under laboratory conditions.
摘要/ ABSTRACT摘要:对橄榄叶蛾(Palpita forficera Munroe, 1959)在橄榄栽培潜力新区的时空分布进行了调查,并评价了生物杀虫剂对橄榄叶蛾的防治效果。由Koroneiki和Arbequina品种组成的实验果园种植在巴西帕拉帕西南地区的帕托布兰科。在田间,每个品种25株,每周进行幼虫计数,为期12个月,以验证其时空分布。此外,在实验室条件下,用印印果油、苏云金芽孢杆菌、绿僵菌和球孢白僵菌处理过的橄榄叶作为对照,比较了4种生物杀虫剂的幼虫死亡率和对照效果。柽柳幼虫主要发生在夏季3个月,寄主偏好“Arbequina”(占总幼虫的68.9%),在果园内随机分布。在实验室条件下,籼稻和苏云金弧菌的幼虫死亡率均接近100%。
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引用次数: 0
Canine atopic dermatitis: systemic immunomodulatory protocol based on clinical phenotype 犬特应性皮炎:基于临床表型的全身免疫调节方案
IF 0.8 4区 农林科学 Q3 AGRONOMY Pub Date : 2023-02-10 DOI: 10.1590/0103-8478cr20220068
Tiago Cunha Ferreira, M. G. M. D. Cunha, D. Nunes-Pinheiro
ABSTRACT: Canine atopic dermatitis (cAD) is a multifactorial allergic disease associated with immune dysfunction and abnormal skin barrier. Several immunological mediators play a role in its pathogenesis. Such molecules are produced by the activation of T helper lymphocytes (Th) through polarization to Th1 and/or Th2, which contributes to different lesion patterns. Acute lesions are mediated by an activation of the Th2 cytokine axis, which clinically induces erythema and pruritus. Conversely, in chronic injuries a mixed immune response of Th1/Th2 cytokines occurs, leading to hyperpigmented and lichenified skin. The clinical understanding of these patterns and the mode of action of immunomodulators are crucial for the best clinical management of the atopic patient. In this context, this review discussed the role of the immune response and the immunomodulatory drugs in dogs with atopic dermatitis and suggested a therapeutic protocol based on clinical phenotype. Based on the evidences showed in this review, it is considered appropriate to use immunomodulatory drugs that target cytokine spectrum related with the clinical phenotype of cAD.
摘要:犬特应性皮炎(cAD)是一种与免疫功能障碍和皮肤屏障异常相关的多因素过敏性疾病。几种免疫介质在其发病机制中起作用。这些分子是由辅助性T淋巴细胞(Th)通过向Th1和/或Th2极化激活而产生的,这有助于不同的病变模式。急性病变是由Th2细胞因子轴的激活介导的,它在临床上诱发红斑和瘙痒。相反,在慢性损伤中,发生Th1/Th2细胞因子的混合免疫反应,导致皮肤色素沉着和地衣化。临床理解这些模式和免疫调节剂的作用模式对特应性患者的最佳临床管理至关重要。在此背景下,本文讨论了免疫反应和免疫调节药物在犬特应性皮炎中的作用,并提出了基于临床表型的治疗方案。基于本综述的证据,我们认为使用针对与cAD临床表型相关的细胞因子谱的免疫调节药物是合适的。
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引用次数: 0
Morada Nova lambs’ meat production potential description through morphometric evaluation 通过形态计量学评价描述莫拉达诺瓦羔羊肉品生产潜力
IF 0.8 4区 农林科学 Q3 AGRONOMY Pub Date : 2023-02-10 DOI: 10.1590/0103-8478cr20210716
Genilson César Alves, W. Vega, H. Costa, R. Silveira, A. Landim
ABSTRACT: Morada Nova breed has a low effective herd, and its white variety is in risk of extinction. The selection of individuals based on breed standard without correlation with productive aptitude is predominant today. We believe that the best way to rescue this valuable genetic resource is to describe its productive potential for commercial use. Thus, this study described the meat production potential of Morada Nova lambs through morphological and zoometric data, performance and carcass characteristics. Twenty-four non-castrated male lambs from two genetic groups were used: Morada Nova red (MNR) and crossbreed Morada Nova (red x Morada Nova white-MNF1) distributed in a completely randomized design. Univariate and multivariate analysis were used. The yields of commercial cuts and the physicochemical characteristics and qualitative measurements of the carcass were similar between the genetic groups. Seven of the 28 characteristics of the carcass were greater in MNF1 lambs. The chest height, rump height and anamorphosis index showed to be important variables in the choice of MN lambs with meat production potential. Based on factor and hierarchical cluster analysis, the Morada Nova beef morphometric index (MNBMI) was created. Both of groups have high thoracic development, ability to produce meat, weight gain, feeding efficiency and breathing capacity, infusing greater rusticity and adaptability; however, the application and validation of the developed index showed superiority for meat production in the crossed lambs. Thus, the MNF1 lambs are a sustainable option for sheep production in drylands.
摘要:莫拉达诺瓦品种有效畜群较低,其白色品种有灭绝的危险。根据品种标准而不与生产能力相关的个体选择在今天占主导地位。我们认为,拯救这一宝贵遗传资源的最佳方法是描述其商业用途的生产潜力。因此,本研究通过形态学和动物计量学数据、生产性能和胴体特征来描述莫拉达诺瓦羔羊的肉类生产潜力。选用莫拉达新星红(MNR)和杂交莫拉达新星(红色×莫拉达新星白- mnf1)两个遗传组24只未阉割公羊羔,采用完全随机设计。采用单因素和多因素分析。两个遗传群之间的商业切肉产量、胴体的理化特性和定性测量结果相似。在28个胴体特征中,MNF1羔羊的7个特征更大。胸高、臀高和畸形指数是选择具有肉品生产潜力的MN羔羊的重要变量。基于因子分析和层次聚类分析,建立了莫拉达诺瓦牛肉形态计量指数(MNBMI)。两组均具有较高的胸部发育、产肉能力、增重能力、饲养效率和呼吸能力,具有较大的生态性和适应性;但该指标的应用和验证表明,该指标在杂交羔羊肉制品生产中具有优势。因此,MNF1羔羊是旱地绵羊生产的可持续选择。
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引用次数: 1
Growth, yield and nutrients of sweet cassava fertilized with zinc 施锌对甜木薯生长、产量及营养的影响
IF 0.8 4区 农林科学 Q3 AGRONOMY Pub Date : 2023-01-13 DOI: 10.1590/0103-8478cr20220064
Jessica Aparecida da Silva, M. Leonel, A. M. Fernandes, F. G. Garreto, J. Nunes, Ricardo Figueiredo Tajra
ABSTRACT: The application of zinc fertilizers in the soil has been an agronomic practice to correct Zn deficiency in plants, aiming to increase productivity and/or nutritional quality. This study evaluated how zinc sulfate fertilization affects plant growth, yield performance and nutrient accumulation in the cassava ‘IAC 576-70’. The experimental design was in randomized blocks with eight replications. The treatments consisted of 0, 1.5, 3.0, 4.5 and 6.0 g p1-1 ZnSO4. Results showed improvement in yield with soil fertilization with ZnSO4, with the optimal dose of 2.5 g pl-1. The uptake of nutrients in plant parts is favored with lower doses of zinc fertilizer, with maximum points ranging from 0.8 to 3.2 g pl-1 for macronutrients and 1.6 to 3.6 g pl-1 for micronutrients. The Zn content in tuberous roots increases by more than 40% with fertilization up to 2.8 g pl-1 of fertilizer, which contributes to the nutritional value of roots.
摘要:在土壤中施用锌肥是纠正植物缺锌的一种农艺做法,旨在提高生产力和营养品质。研究了硫酸锌施肥对木薯‘IAC 576-70’植株生长、产量和养分积累的影响。试验设计为随机分组,每组8个重复。处理分别为0、1.5、3.0、4.5和6.0 g p1-1 ZnSO4。结果表明,土壤施肥ZnSO4可提高产量,最佳施肥剂量为2.5 g pl-1。较低剂量的锌肥有利于植物各部位对营养物质的吸收,大量营养素的最大值为0.8 ~ 3.2 g / l,微量营养素的最大值为1.6 ~ 3.6 g / l。施肥2.8 g / l时,块根锌含量增加40%以上,有利于块根的营养价值。
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引用次数: 0
Epizootiology of canine distemper in naturally infected dogs in Goiânia, Brazil 巴西goi<e:1>尼亚自然感染犬犬瘟热的流行病学研究
IF 0.8 4区 农林科学 Q3 AGRONOMY Pub Date : 2023-01-13 DOI: 10.1590/0103-8478cr20220166
Karolina Martins Ferreira Menezes, Gladsthon Divino de Sousa Filho, A. D. Damasceno, Menira Souza, Bruno Benetti Junta Torres
ABSTRACT: Although the epizootiological profile of canine distemper in Goiânia is unknown, there is clinical evidence for a high incidence of canine distemper virus (CDV) infection among dogs. Therefore, this study determined the epizootiological characteristics of canine distemper in naturally infected dogs. Data of 46 dogs that tested positive for the CDV based on immunochromatography or reverse transcription-polymerase chain reaction were collected. Data on the sex, breed, age, and vaccination status were obtained from these dogs, and extraneural and neural sign analyses were performed. Although, the infected dogs belonged to both sexes, different breeds, and different age groups, a greater proportion of cases were seen in adults (1-6 years), undefined breeds, and unvaccinated dogs. Among the CDV-positive dogs, 10.87% had been vaccinated. In addition, 4.35% showed neural signs, 8.69% showed extraneural signs, and 86.96% showed both. High lethality was observed, with viral antigen and/or DNA detected in 82.61% dead dogs. Only 8.70% of the total CDV-infected dogs remained alive at the time of their assessment.
摘要:尽管狼疮犬犬瘟热的流行病学特征尚不清楚,但有临床证据表明犬瘟热病毒(CDV)感染在犬类中的发病率很高。因此,本研究确定了自然感染犬犬瘟热的流行病学特征。收集了46只经免疫层析或逆转录聚合酶链反应检测为CDV阳性的狗的数据。从这些狗身上获得了性别、品种、年龄和疫苗接种状况的数据,并进行了神经外和神经体征分析。虽然受感染的狗属于两性、不同品种和不同年龄组,但更大比例的病例发生在成人(1-6岁)、未确定品种和未接种疫苗的狗身上。接种疫苗的犬只比例为10.87%。4.35%表现为神经征象,8.69%表现为神经外征象,86.96%表现为两者兼而有之。死亡率高,82.61%的死犬检出病毒抗原和/或DNA。在接受评估时,感染了cdc的犬只中只有8.70%存活。
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引用次数: 0
Factors determining farmers’ access to agricultural credit in Turkey 决定土耳其农民获得农业信贷的因素
IF 0.8 4区 农林科学 Q3 AGRONOMY Pub Date : 2023-01-13 DOI: 10.1590/0103-8478cr20210916
U. Gültekin
ABSTRACT: This study assessed the parameters determining the access of producers to agricultural credit in Turkey. This research was carried out in the production areas par excellence of the country. A total of 409 producers have been surveyed. The data collected was collected during the first quarter of 2021 and relates to the socio-economic and demographic characteristics of producers as well as the factors likely to influence their access to agricultural credit. The analysis of the results from the logistic regression model produced shows that the access of producers to agricultural credit is determined by their socio-economic and demographic characteristics. These parameters are level of education, degree of involvement in agricultural activities, social security status, household size and whether you own a tractor. Given the importance of agricultural credit for the agricultural sector; it is therefore, imperative to facilitate its access to producers.
摘要:本研究评估了决定土耳其生产者获得农业信贷的参数。这项研究是在全国最优秀的生产地区进行的。共有409家生产商接受了调查。所收集的数据是在2021年第一季度收集的,涉及生产者的社会经济和人口特征以及可能影响其获得农业信贷的因素。对logistic回归模型结果的分析表明,生产者获得农业信贷的机会是由其社会经济和人口特征决定的。这些参数包括教育水平、参与农业活动的程度、社会保障状况、家庭规模以及是否拥有拖拉机。鉴于农业信贷对农业部门的重要性;因此,必须便利其进入生产者。
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引用次数: 0
Characterization of new late-spring-frost-tolerant apricot hybrids: physical and biochemical fruit quality attributes, volatile aroma compounds 晚春耐霜冻杏新品种鉴定:果实物理生化性状、挥发性香气化合物
IF 0.8 4区 农林科学 Q3 AGRONOMY Pub Date : 2023-01-06 DOI: 10.1590/0103-8478cr20220144
Aliseydi Doğan, Karaat Fırat Ege, O. Levent, B. Asma
ABSTRACT: Late spring frosts is one of the most important restricting abiotic stress factors of apricot growing worldwide. In this study; some physical, biochemical fruit quality characteristics and volatile aroma compounds were determined in fresh fruit samples of thirteen late spring frost tolerant apricot hybrids recently obtained from Turkish apricot breeding programme. A wide variation was reported among apricot genotypes in all of the evaluated physical and biochemical fruit characteristics and also volatile aroma compounds.Fruit size varied between 27.2 and 60.5 g, total soluble solids between 13.6 and 17.4 %, total carotene 26.6 and 42.8 (mg.100 g-1), and total phenolics content 354.2 and 673.1 (GAE.100 g-1). A total of 42 flavor components belonging to various flavor compound groups were identified. The main volatile aroma compound groups detected in the assessed apricot genotypes were; aldehydes, ketones, esters, alcohols, terpenes, acids, and other compounds. Among the detected compounds; Hexanal, 2-Hexenal, 1-Hexanol, 2-Hexen-1-ol, Limonene were the most abundant compounds in terms of concentration. Hexanal varied between 55.8 and 528.5 µg.kg-1, and 2-Hexen-1-ol changed between 25.7 and 297.9 µg.kg-1 fresh weight. Correlation analysis revealed significant correlations among some aroma compounds and biochemical fruit quality characteristics. Significant correlations were reported for esters with titratable acidity (r=0.79) and total carotene (r=-0.61) and aldehydes were found as highly correlated with total soluble solids (r=-0.69). The results of the study will be beneficial in terms of food analysis, cultivation, and breeding studies of apricot.
摘要:晚春霜冻是制约杏生长的重要非生物胁迫因子之一。在本研究中;对土耳其杏育种项目选育的13个晚春抗冻杏杂交种鲜果样品进行了果实物理、生化特性和挥发性香气成分的测定。结果表明,不同基因型杏在果实物理生化特性和挥发性香气化合物方面存在较大差异。果实大小在27.2 ~ 60.5 g之间,总可溶性固形物在13.6 ~ 17.4%之间,总胡萝卜素在26.6 ~ 42.8 mg之间。总酚类物质含量354.2和673.1 (GAE.100 g-1)。共鉴定出42种风味成分,属于不同的风味化合物群。鉴定杏基因型中检测到的主要挥发性香气化合物组有;醛、酮、酯、醇、萜烯、酸和其他化合物。在检测到的化合物中;己醛、2-己烯醛、1-己醇、2-己烯-1-醇、柠檬烯的含量最高。己醛在55.8µg和528.5µg之间变化。kg-1和2-己烯-1-醇在25.7和297.9µg之间变化。公斤-1鲜重。相关分析显示,部分香气成分与果实生化品质性状具有显著的相关性。可滴定酸度的酯类(r=0.79)和总胡萝卜素(r=-0.61)之间存在显著相关性,醛类与总可溶性固形物高度相关(r=-0.69)。研究结果对杏的食品分析、栽培和育种研究具有一定的指导意义。
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引用次数: 1
Cerebral infarction and thrombotic meningoencephalitis in a calf due to candidiasis 脑梗死和血栓性脑膜脑炎小牛由于念珠菌病
IF 0.8 4区 农林科学 Q3 AGRONOMY Pub Date : 2023-01-06 DOI: 10.1590/0103-8478cr20220254
R. C. Alves, Y. G. Soares, F. K. Carvalho, L. A. Maia, C. Barros, F. Riet-Correa, A. Dantas, G. J. Galiza
ABSTRACT: We described a case of cerebral infarction and thrombotic meningoencephalitis due to candidiasis in a seven-month-old calf. The death occurred three days after the onset of apathy, fever, and the head’s lateral deviation to the left. Macroscopic changes in the brain consisted of asymmetry of telencephalic hemispheres; the right hemisphere was enlarged, causing cerebellar herniation. A focally extensive red area was observed on the surface of the right occipital lobe. At cross-sections of the fixed brain, the lesions revealed to be extensive, red-brown, soft or cavitated areas affecting the white and grey matter from the level of the thalamus to the cerebellum and compressing subjacent structures. Histologically, there was acute, coalescent, multifocal necrosupurative meningoencephalitis, associated with vasculitis, congestion, thrombosis, edema, infarction, and intralesional fungal hyphae. The diagnosis of cerebral infarction and thrombotic meningoencephalitis due to candidiasis was made by the pathological changes, the staining and morphological characteristics of the agent, and immunohistochemistry. The cerebral infarction and thrombotic meningoencephalitis in cattle can result from vascular lesions due to infection by Candida sp.; although uncommon, this case demonstrated that candidiasis should be part of a list of differential diagnoses of severe brain injuries in cattle.
摘要:我们报道了一例由念珠菌病引起的脑梗死和血栓性脑膜脑炎,发生于7个月大的小牛。死亡发生在患者出现冷漠、发热和头部向左侧偏3天后。大脑的宏观变化包括端脑半球的不对称;右半球肿大,引起小脑疝。右侧枕叶表面可见局部广泛的红色区域。在固定脑的横截面上,病变显示为广泛的、红棕色的、柔软的或空化的区域,影响从丘脑到小脑的白质和灰质,并压迫下皮层结构。组织学上表现为急性、合并、多灶性坏死性化脓性脑膜脑炎,伴血管炎、充血、血栓形成、水肿、梗死和病灶内真菌菌丝。通过病理改变、制剂的染色和形态特征及免疫组织化学诊断念珠菌病所致脑梗死和血栓性脑膜脑炎。牛的脑梗死和血栓性脑膜脑炎可由念珠菌感染引起的血管病变引起;虽然不常见,但该病例表明,念珠菌病应列入牛严重脑损伤的鉴别诊断清单。
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Ciencia Rural
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