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Comparative Evaluation of Hardness and Energy Absorption of Some Commercially Available Chairside Silicone-Based Soft Denture Liners and a Heat-Cured Soft Denture Liner. 一些市售的链状硅树脂基软义齿衬垫和热固化软义齿衬垫的硬度和能量吸收的比较评估。
IF 1.5 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-10-04 eCollection Date: 2023-01-01 DOI: 10.2147/CCIDE.S433519
Mahdi Mutahar, Nasser M Al Ahmari, Thrya S Gadah, Mohammed Ali Mohammed Kariri, Hana Y Madkhli, Dawood M Somaili, Yahya M Y Mobarki, Omar Ahmed Darraj, Sultan M Halawi, Mohammed M Al Moaleem

Aim: To investigate the hardness and energy absorption of four commercially available chairside types of silicone materials and compare their properties with heat-cured silicone material.

Materials: The chairside materials investigated were GC reline soft, mucopren soft, sofreliner soft and elite soft relining. The heat-cured polymer silicone material was Molloplast B. All soft lining materials were processed according to manufacturers' instructions. Two properties were investigated. Ten specimens for each test were prepared for each soft liner except for the water absorption and solubility test, for which only five specimens were prepared. The specimens of energy absorption (10 × 10 × 3 mm) were tested using a Lloyd instruments testing machine. Hardness specimens (38 × 38 × 3) were tested using a shore A durometer and were divided into two subgroups; dry and wet storage.

Results: The specimens of energy absorption (10 × 10 × 3 mm) were tested using a Lloyd instruments testing machine. Sofreliner soft was significantly softer than Molloplast B. GC reline soft was significantly harder than molloplast B. At high loads, sofreliner soft and elite soft relining was significantly more resilient than molloplast B. Mucopren soft was significantly stiffer than Molloplast B. At low loads, all materials showed similarities in stiffness and resilience; the difference between them was insignificant. After one month of immersion, GC reline and mucopren significantly increased hardness values.

Conclusion: In all conditions and at all four-time points, the hardness values for GC Reline soft were the greatest, and hardness values for Sofreliner Soft were the least. Some chairside soft denture lining materials could have similar significant properties to molloplast-B, such as sofreliner soft and elite.

目的:研究四种市售椅旁型有机硅材料的硬度和能量吸收,并将其与热固化有机硅材料的性能进行比较。材料:所研究的椅侧材料为GC软质、粘蛋白软质、软质和精英软质。热固化聚合物硅酮材料为Molloplast B。所有软衬里材料均按照制造商的说明进行加工。研究了两种性质。除吸水性和溶解性试验外,每个软衬管各制备10个试样,其中仅制备5个试样。用Lloyd仪器测试机测试了能量吸收试样(10×10×3mm)。硬度试样(38×38×3)用肖氏a硬度计进行测试,并分为两组;干湿储存。结果:采用Lloyd仪器试验机对10×。软质软质换衬层明显比软质B软。GC软质换内衬明显比软性B硬。在高负荷下,软质换衬里和优质软质换衬垫的弹性明显高于软质B。软质粘蛋白明显比软体B硬。低负荷下,所有材料的刚度和弹性相似;它们之间的差异是微不足道的。浸泡一个月后,GC reline和粘异戊二烯的硬度值显著增加。结论:在所有条件下和所有四个时间点,GC Reline软硬度值最大,Sofreliner软硬度值最小。一些椅侧软质义齿衬料可能具有与molloplast-B类似的显著性能,如软质软质和精英质软质。
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引用次数: 0
A Case Report of a Maxillary Second Molar with Two Distinct Palatal Canals, Confirmed by CBCT. CBCT证实上颌第二磨牙有两个不同的腭管的病例报告。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-09-26 eCollection Date: 2023-01-01 DOI: 10.2147/CCIDE.S431563
Aladdin Al-Qudah, Asem Afaneh, Layla Hassouneh

Cases of unusual and complex root canal morphology could be difficult to diagnose and treat. This report describes the diagnosis and management of a rare maxillary right second molar (tooth #17) with two distinct palatal canals. The tooth was diagnosed with irreversible pulpitis and symptomatic apical periodontitis. Non-surgical root canal treatment was performed. Accurate diagnosis and comprehensive treatment of cases with unusual root canal morphology can be achieved by evaluation of periapical radiographs at different angulations, advanced magnification techniques, and the Cone Beam Computed Tomography (CBCT) scanning. Clinicians should be aware that two separate palatal canals could exist in maxillary second molar teeth.

异常和复杂根管形态的病例可能难以诊断和治疗。本报告描述了一个罕见的上颌右第二磨牙(17号牙)的诊断和治疗,该磨牙有两个不同的腭道。该牙齿被诊断为不可逆牙髓炎和症状性根尖周炎。进行了非手术根管治疗。通过评估不同角度的根尖周x线片、先进的放大技术和锥形束计算机断层扫描(CBCT)扫描,可以对具有异常根管形态的病例进行准确诊断和综合治疗。临床医生应注意,上颌第二磨牙可能存在两个独立的腭道。
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引用次数: 0
The Association Between Skeletal Facial Types and Third Molars Impaction in a Saudi Arabian Subpopulation: A CBCT Study. 沙特阿拉伯亚群中骨骼面部类型与第三磨牙撞击的关系:CBCT研究。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-08-15 eCollection Date: 2023-01-01 DOI: 10.2147/CCIDE.S419325
Muslat A Bin Rubaia'an, Aymen Neyaz, Faisal Talic, Ali Alkhamis, Abdulmalek Alghabban, Ahmad Assari

Purpose: To assess the state of mandibular and maxillary third molars in relation to different facial types in a Saudi population using cone-beam computed tomography (CBCT) records.

Patients and methods: A retrospective study was performed on CBCTs. Statistical analysis determined the relationship between impacted maxillary and mandibular third molars and different skeletal facial types. The degree of third molar impaction was evaluated.

Results: A total of 198 CBCTs from subjects were evaluated, with a mean age of 34.2 years. Archer II classification was found to be significantly associated with all skeletal profiles. The incidence of mesioangular impactions in lower third molar showed a notable increase in the brachyfacial group, which was statistically significant.

Conclusion: In conclusion, this study demonstrates that different facial types are associated with the angulation of third molar impactions.

目的:使用锥形束计算机断层扫描(CBCT)记录评估沙特人群中下颌和上颌第三磨牙与不同面部类型的关系。患者和方法:对CBCT进行回顾性研究。统计分析确定了上颌和下颌阻生第三磨牙与不同骨面类型之间的关系。评估第三磨牙嵌塞的程度。结果:共评估了198名受试者的CBCT,平均年龄为34.2岁。Archer II分类被发现与所有骨骼轮廓显著相关。近面组下第三磨牙近角咬合的发生率显著增加,具有统计学意义。结论:总之,本研究表明,不同的面部类型与第三磨牙咬合的角度有关。
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引用次数: 0
Morphological Interface Between Restorative and Pulp-Capping Materials: A Systematic Review. 修复材料与牙髓覆盖材料之间的形态界面:系统综述。
IF 1.5 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-06-05 eCollection Date: 2023-01-01 DOI: 10.2147/CCIDE.S414418
Natnael Teshome Desta

Background: Bioceramic materials (BCMs) are widely used in vital pulp therapy (VPT) for their biocompatibility and bioactivity; however, their mechanical properties are equally important in the clinical outcome of the pulp-capped teeth.

Objective: To carry out an analysis of the research produced on the morphology of the interface between BM and restorative materials (RM) through a systematic review.

Methodology: An electronic search was performed in Scopus, PubMed, and Web of Science until December 9, 2022. The keywords used in combination with truncation and Boolean operators were: (morphology OR filtration OR porosity) AND (silicate OR composite) AND (cement) AND ("pulp capping" OR "vital pulp therapy" OR "vital pulp treatment").

Results: Of the 387 articles initially retrieved from the electronic search databases, 5 articles met the criteria for qualitative data collection. MTA and Biodentine were the most studied BCMs. All the articles used a scanning electron microscope as a method of evaluating the samples. Sample sizes and setting times of RM and BCMs differed between studies. Three out of 5 studies used similar conditions of recorded temperature and humidity of 37°C and 100%, respectively.

Conclusion: The different biomaterials used, the application of adhesive systems, humidity and restoration time affect the bonding performance and the ultrastructural interface between BCMs and RMs. The scarcity of research on this point makes it necessary to delve into it and study new materials to obtain more scientific evidence.

背景:生物陶瓷材料(BCMs)因其生物相容性和生物活性而被广泛应用于牙髓治疗(VPT);然而,其机械性能对牙髓覆盖牙的临床效果同样重要:通过系统综述,对有关牙髓与修复材料(RM)界面形态的研究进行分析:在 Scopus、PubMed 和 Web of Science 中进行了电子检索,截止日期为 2022 年 12 月 9 日。结合截断和布尔运算符使用的关键词有(形态或过滤或孔隙率)和(硅酸盐或复合材料)和(水泥)和("牙髓盖髓 "或 "牙髓治疗 "或 "牙髓治疗"):在电子检索数据库中初步检索到的 387 篇文章中,有 5 篇符合定性数据收集标准。MTA和Biodentine是研究最多的BCM。所有文章都使用扫描电子显微镜作为评估样本的方法。不同研究中,RM 和 BCM 的样本量和设置时间各不相同。5项研究中有3项使用了类似的记录条件,温度和湿度分别为37°C和100%:结论:所使用的不同生物材料、粘合剂系统的应用、湿度和修复时间都会影响BCM和RM之间的粘合性能和超微结构界面。这方面的研究很少,因此有必要对其进行深入研究,并对新材料进行研究,以获得更多科学证据。
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引用次数: 0
The Prevalence and Significance of Fissured Tongue in Kabul City Among Dental Patients. 喀布尔市牙科患者舌裂的患病率及意义
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-01-01 DOI: 10.2147/CCIDE.S391498
Hedayatullah Ehsan, Shamila Azimi, Abubakr Yosufi, Roqia Yousufi

Background: The tongue is known as the mirror of oral and general health. Some diseases may show signs in the tongue. Fissured is approximately an asymptomatic condition characterized by grooves and fissures of varying depth on the dorsal surface of the tongue. Epidemiologically, its prevalence is varied based on different factors, but most of them report 10-20%.

Methods: In the department of oral medicine at Ali-Abad University Hospital of Kabul University of Medical Sciences, a cross-sectional study was conducted among 400 patients. This fissured tongue is first diagnosed based on clinical appearance (fissures) on each side of tongue. Meanwhile, the whole medical and dental histories were taken for the rest of the leading factors.

Results: Out of 400 patients (124 males and 276 females) seen and checked, which 142 cases were fissured tongue [45 (31.7%) males and 97 (68.3%) females]. The fissures were found to be least in the >10 - 19-year age group, 23 (16.3%) and it was most prevalent in the 20 -39 age group, 73 (51.8%), followed by 40 -59, 35 (24.8%) and 60< age group, 10 (7.1%). The most prevalent type of pattern of fissures was found to be superficial, multiple and not connected fissures, 46.32% (33.3% males, 32.3% females), followed by superficial, multiple and connected fissures, 25.5% (26.7% males, 25% females), and whereas 6.4% of patients with (single and deep type of fissure) was the lowest prevalent type of fissured tongue. In our study, more than half of patients asymptomatic (51.6% females and 71.1% males), 17.9% complained from tongue dryness, 14.3% soreness, 6.4% halitosis, 1.4% tongue swelling and 2.1% had all the signs.

Conclusion: The prevalence of fissured tongue was 35.5%. A significant difference between genders was reported with female predominance in all cases observed. The most prevalent age groups were 20-29 and 30-39 in both gender groups. Superficial, multiple, and not connected fissures 46.32% were the most common type of fissure.

背景:舌头被认为是口腔和全身健康的镜子。有些疾病可能在舌头上表现出来。舌裂是一种无症状的症状,其特征是舌背表面有不同深度的沟槽和裂缝。在流行病学上,其患病率因不同因素而异,但大多数报告为10-20%。方法:对喀布尔医科大学阿里阿巴德大学附属医院口腔内科400例患者进行横断面研究。这种舌裂首先是根据舌两侧的临床表现(裂隙)来诊断的。与此同时,所有的医疗和牙科病史都被记录下来,以确定其他主要因素。结果:400例患者中,男124例,女276例,舌裂142例,其中男45例(31.7%),女97例(68.3%)。>10 ~ 19岁年龄组发生的牙裂最少,为23例(16.3%),20 ~ 39岁年龄组最多,为73例(51.8%),其次为40 ~ 59岁,35例(24.8%),60岁以下年龄组10例(7.1%)。舌裂类型以浅裂、多裂和不连裂最为常见,占46.32%(男性33.3%,女性32.3%);其次为浅裂、多裂和连裂,占25.5%(男性26.7%,女性25%);舌裂类型(单裂和深裂)患病率最低,占6.4%。在我们的研究中,超过一半的患者无症状(女性51.6%,男性71.1%),17.9%的患者表现为舌干,14.3%的患者表现为疼痛,6.4%的患者表现为口臭,1.4%的患者表现为舌肿,2.1%的患者表现为所有症状。结论:舌裂患病率为35.5%。据报道,在所有观察到的病例中,性别之间存在显著差异,女性占优势。在男女两组中,最常见的年龄组是20-29岁和30-39岁。浅表性、多发性和非连通性裂隙是最常见的裂隙类型,占46.32%。
{"title":"The Prevalence and Significance of Fissured Tongue in Kabul City Among Dental Patients.","authors":"Hedayatullah Ehsan,&nbsp;Shamila Azimi,&nbsp;Abubakr Yosufi,&nbsp;Roqia Yousufi","doi":"10.2147/CCIDE.S391498","DOIUrl":"https://doi.org/10.2147/CCIDE.S391498","url":null,"abstract":"<p><strong>Background: </strong>The tongue is known as the mirror of oral and general health. Some diseases may show signs in the tongue. Fissured is approximately an asymptomatic condition characterized by grooves and fissures of varying depth on the dorsal surface of the tongue. Epidemiologically, its prevalence is varied based on different factors, but most of them report 10-20%.</p><p><strong>Methods: </strong>In the department of oral medicine at Ali-Abad University Hospital of Kabul University of Medical Sciences, a cross-sectional study was conducted among 400 patients. This fissured tongue is first diagnosed based on clinical appearance (fissures) on each side of tongue. Meanwhile, the whole medical and dental histories were taken for the rest of the leading factors.</p><p><strong>Results: </strong>Out of 400 patients (124 males and 276 females) seen and checked, which 142 cases were fissured tongue [45 (31.7%) males and 97 (68.3%) females]. The fissures were found to be least in the >10 - 19-year age group, 23 (16.3%) and it was most prevalent in the 20 -39 age group, 73 (51.8%), followed by 40 -59, 35 (24.8%) and 60< age group, 10 (7.1%). The most prevalent type of pattern of fissures was found to be superficial, multiple and not connected fissures, 46.32% (33.3% males, 32.3% females), followed by superficial, multiple and connected fissures, 25.5% (26.7% males, 25% females), and whereas 6.4% of patients with (single and deep type of fissure) was the lowest prevalent type of fissured tongue. In our study, more than half of patients asymptomatic (51.6% females and 71.1% males), 17.9% complained from tongue dryness, 14.3% soreness, 6.4% halitosis, 1.4% tongue swelling and 2.1% had all the signs.</p><p><strong>Conclusion: </strong>The prevalence of fissured tongue was 35.5%. A significant difference between genders was reported with female predominance in all cases observed. The most prevalent age groups were 20-29 and 30-39 in both gender groups. Superficial, multiple, and not connected fissures 46.32% were the most common type of fissure.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"15 ","pages":"21-29"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cd/af/ccide-15-21.PMC9969861.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10812323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Domains of Students' Concerns in Oral Diagnosis and Surgery Clinic. 口腔诊断与外科临床学生关注的领域。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-01-01 DOI: 10.2147/CCIDE.S425318
Ahmad Fliah Hassan, Faaiz Yaqub Alhamdani, Hani Radhi, Hashim Mueen Hussein

Background: Oral diagnosis and surgery education is the main educational subject in dental schools. Due to its importance and the demand to achieve a proper level of training, dental students might have some concerns related to this subject. The study aims to investigate domains related to students' concerns in oral surgery clinics.

Materials and method: An online questionnaire of five domains was circulated to 211 fourth, and fifth-year students. The domains include; the benefit of oral surgery lectures in oral surgery clinic; the importance of oral surgery clinic, what they fear the most during their oral surgery training; difficulty domain, and importance domain. It was distributed to a sample of 211 fourth-, and fifth-year students at the Ibn Sina College of Dentistry, Baghdad, Iraq in January, and February 2022.

Results: In the domain of "benefit of oral surgery lectures in the oral surgery clinic" Half of the respondents think theory lectures are useful. About one-third of the students believe it is essential. The most important item in the domain of "most factors students' fear" was the item of nerve injury (42.1%). Incomplete tooth removal was reported in (32.7%), whereas post-extraction bleeding was reported by (19.2%). In the domain "the most difficult" 71% of students stated that it is dealing with uncooperative patients was the most important item. Similarly, in the domain "the most important" the majority of students reported that correct surgical diagnosis (70.1%) is the most important item, followed by master extraction technique (26.2%), and master anesthesia technique (3.7%).

Conclusion: This study evaluated the "fear", "difficulty", and "importance" domains of students' concerns during oral surgery training. There is a noticeable shift in students' attention toward clinical reasoning compared to the technical aspects of surgical training. This positive shift reflects the perceived importance of diagnosis for proper clinical practice. This needs to be encouraged by the teaching staff.

背景:口腔诊断与外科学教育是口腔医学院校的主要教学内容。由于它的重要性和需要达到适当的训练水平,牙科学生可能会对这个主题有一些担忧。本研究旨在探讨学生在口腔外科诊所所关注的相关领域。资料与方法:对211名四、五年级学生进行了5个领域的在线问卷调查。这些领域包括;口腔外科讲座在口腔外科诊所的益处口腔外科诊所的重要性,他们在口腔外科培训中最害怕什么;难度域和重要性域。该研究于2022年1月和2月在伊拉克巴格达伊本西纳牙科学院的211名四年级和五年级学生中进行了分发。结果:在“口腔外科讲座在口腔外科诊所的效益”方面,有一半的受访者认为理论讲座是有用的。大约三分之一的学生认为这是必要的。在“学生最害怕的因素”中,最重要的是神经损伤(42.1%)。拔牙不全者占32.7%,拔牙后出血者占19.2%。在“最困难的”一项中,71%的学生表示处理不合作的病人是最重要的项目。同样,在“最重要”领域中,大多数学生认为正确的手术诊断(70.1%)是最重要的项目,其次是熟练的拔牙技术(26.2%)和熟练的麻醉技术(3.7%)。结论:本研究评估了学生在口腔外科培训中所关注的“恐惧”、“困难”和“重要”三个领域。与外科训练的技术方面相比,学生对临床推理的关注有明显的转变。这种积极的转变反映了诊断对正确临床实践的重要性。这需要教师的鼓励。
{"title":"Domains of Students' Concerns in Oral Diagnosis and Surgery Clinic.","authors":"Ahmad Fliah Hassan,&nbsp;Faaiz Yaqub Alhamdani,&nbsp;Hani Radhi,&nbsp;Hashim Mueen Hussein","doi":"10.2147/CCIDE.S425318","DOIUrl":"https://doi.org/10.2147/CCIDE.S425318","url":null,"abstract":"<p><strong>Background: </strong>Oral diagnosis and surgery education is the main educational subject in dental schools. Due to its importance and the demand to achieve a proper level of training, dental students might have some concerns related to this subject. The study aims to investigate domains related to students' concerns in oral surgery clinics.</p><p><strong>Materials and method: </strong>An online questionnaire of five domains was circulated to 211 fourth, and fifth-year students. The domains include; the benefit of oral surgery lectures in oral surgery clinic; the importance of oral surgery clinic, what they fear the most during their oral surgery training; difficulty domain, and importance domain. It was distributed to a sample of 211 fourth-, and fifth-year students at the Ibn Sina College of Dentistry, Baghdad, Iraq in January, and February 2022.</p><p><strong>Results: </strong>In the domain of \"benefit of oral surgery lectures in the oral surgery clinic\" Half of the respondents think theory lectures are useful. About one-third of the students believe it is essential. The most important item in the domain of \"most factors students' fear\" was the item of nerve injury (42.1%). Incomplete tooth removal was reported in (32.7%), whereas post-extraction bleeding was reported by (19.2%). In the domain \"the most difficult\" 71% of students stated that it is dealing with uncooperative patients was the most important item. Similarly, in the domain \"the most important\" the majority of students reported that correct surgical diagnosis (70.1%) is the most important item, followed by master extraction technique (26.2%), and master anesthesia technique (3.7%).</p><p><strong>Conclusion: </strong>This study evaluated the \"fear\", \"difficulty\", and \"importance\" domains of students' concerns during oral surgery training. There is a noticeable shift in students' attention toward clinical reasoning compared to the technical aspects of surgical training. This positive shift reflects the perceived importance of diagnosis for proper clinical practice. This needs to be encouraged by the teaching staff.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"15 ","pages":"157-163"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/6d/41/ccide-15-157.PMC10454740.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10109257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reduction of Inflammatory RANTES/CCL5 Serum Levels by Surgery in Patients with Bone Marrow Defects of the Jawbone. 下颌骨骨髓缺损患者手术后血清炎性RANTES/CCL5水平的降低
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-01-01 DOI: 10.2147/CCIDE.S417783
Joé Diederich, Hendrik Schwagten, Georges Biltgen, Johann Lechner, Kurt E Müller

Purpose: The presence of bone marrow defects of the jawbone (BMDJ) is associated with increased levels of inflammatory cytokines such as RANTES/CCL5. The purpose of this study was to analyze if BMDJ therapy under real-world conditions reduces RANTES/CCL5 serum levels in BMDJ patients.

Patients and methods: During this retrospective study, 113 BMDJ patients received either no treatment (n = 57), BMDJ surgery (n = 25), tooth extraction (n = 20), or root canal treatment (n = 11). Serum concentrations of RANTES/CCL5, C-reactive protein (CRP), and Tumor Necrosis Factor-α (TNF-α) were assessed before and after treatment (interventional group) and at the beginning and end of the study period (control group). Statistical analyses of the results were performed by the two-sample t-test and Bonferroni post hoc test with ANOVA for multiple comparisons.

Results: BMDJ were detected in all patients with 4.42 ± 2.75 BMDJ findings per patient. RANTES/CCL5 levels were significantly reduced by any treatment when compared to no treatment (p < 0.001; effect size d = 0.90). This effect was most pronounced in the BMDJ surgery group (p < 0.001; effect size d = 1.30). In contrast, RANTES/CCL5 serum concentrations further increased in untreated patients. Mean duration between pre- and post-treatment RANTES/CCL5 measurements was 22.86 ± 19.36 weeks, with no correlation with RANTES/CCL5 levels in any interventional group or in the total sample (p = 0.104).

Conclusion: BMDJ surgery, tooth extraction, and root canal treatment significantly reduce RANTES/CCL5 serum concentrations in BMDJ patients, with surgery being most beneficial. Further research is required to establish regular RANTES/CCL5 assessments as part of an improved diagnosis, monitoring, and evaluation of therapy success in BMDJ patients.

目的:颌骨骨髓缺损(BMDJ)的存在与炎性细胞因子(如RANTES/CCL5)水平升高有关。本研究的目的是分析现实条件下BMDJ治疗是否降低BMDJ患者的RANTES/CCL5血清水平。患者和方法:在本回顾性研究中,113例BMDJ患者接受了未治疗(n = 57)、BMDJ手术(n = 25)、拔牙(n = 20)或根管治疗(n = 11)。在治疗前后(介入组)和研究开始和结束时(对照组)评估血清RANTES/CCL5、c反应蛋白(CRP)和肿瘤坏死因子-α (TNF-α)浓度。统计分析采用双样本t检验和Bonferroni事后检验,多组比较采用方差分析。结果:所有患者均检出BMDJ,平均每例患者有4.42±2.75个BMDJ。与未治疗相比,任何治疗均显著降低RANTES/CCL5水平(p < 0.001;效应量d = 0.90)。这种效果在BMDJ手术组最为明显(p < 0.001;效应量d = 1.30)。相比之下,未经治疗的患者RANTES/CCL5血清浓度进一步升高。治疗前后RANTES/CCL5测量的平均持续时间为22.86±19.36周,与任何干预组或总样本的RANTES/CCL5水平无关(p = 0.104)。结论:BMDJ手术、拔牙和根管治疗可显著降低BMDJ患者血清RANTES/CCL5浓度,其中手术是最有利的。需要进一步的研究来建立常规的RANTES/CCL5评估,作为改进BMDJ患者治疗成功的诊断、监测和评估的一部分。
{"title":"Reduction of Inflammatory RANTES/CCL5 Serum Levels by Surgery in Patients with Bone Marrow Defects of the Jawbone.","authors":"Joé Diederich,&nbsp;Hendrik Schwagten,&nbsp;Georges Biltgen,&nbsp;Johann Lechner,&nbsp;Kurt E Müller","doi":"10.2147/CCIDE.S417783","DOIUrl":"https://doi.org/10.2147/CCIDE.S417783","url":null,"abstract":"<p><strong>Purpose: </strong>The presence of bone marrow defects of the jawbone (BMDJ) is associated with increased levels of inflammatory cytokines such as RANTES/CCL5. The purpose of this study was to analyze if BMDJ therapy under real-world conditions reduces RANTES/CCL5 serum levels in BMDJ patients.</p><p><strong>Patients and methods: </strong>During this retrospective study, 113 BMDJ patients received either no treatment (n = 57), BMDJ surgery (n = 25), tooth extraction (n = 20), or root canal treatment (n = 11). Serum concentrations of RANTES/CCL5, C-reactive protein (CRP), and Tumor Necrosis Factor-α (TNF-α) were assessed before and after treatment (interventional group) and at the beginning and end of the study period (control group). Statistical analyses of the results were performed by the two-sample <i>t</i>-test and Bonferroni post hoc test with ANOVA for multiple comparisons.</p><p><strong>Results: </strong>BMDJ were detected in all patients with 4.42 ± 2.75 BMDJ findings per patient. RANTES/CCL5 levels were significantly reduced by any treatment when compared to no treatment (p < 0.001; effect size d = 0.90). This effect was most pronounced in the BMDJ surgery group (p < 0.001; effect size d = 1.30). In contrast, RANTES/CCL5 serum concentrations further increased in untreated patients. Mean duration between pre- and post-treatment RANTES/CCL5 measurements was 22.86 ± 19.36 weeks, with no correlation with RANTES/CCL5 levels in any interventional group or in the total sample (p = 0.104).</p><p><strong>Conclusion: </strong>BMDJ surgery, tooth extraction, and root canal treatment significantly reduce RANTES/CCL5 serum concentrations in BMDJ patients, with surgery being most beneficial. Further research is required to establish regular RANTES/CCL5 assessments as part of an improved diagnosis, monitoring, and evaluation of therapy success in BMDJ patients.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"15 ","pages":"181-188"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/72/af/ccide-15-181.PMC10496923.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10260541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of Patient Anthropometric Measurements and Dental Implant Treatment. 患者人体测量与种植牙治疗的关联。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-01-01 DOI: 10.2147/CCIDE.S406119
Afya Sahib Diab Al-Radha

Background: Dental implants are currently one of the most preferred treatment modalities for replacing missing teeth, as they are the most comparable to natural teeth. Even so, satisfaction with such treatment may differ depending on patient nature. The aim of this article was to examine the relationships between different anthropometric measurements on dental implant patient's satisfaction.

Methods and material: Self-administered questionnaire (structured questions) were given to patients who had dental implant treatment to evaluate their satisfaction level with dental-implant treatment. Different anthropometric measurements were taken: body height; weight; body mass index (BMI); body composition; waist/hip ratio; and circumferences at the waist, hip, and neck.

Results: The overall BMI was 28.9±4.7 kg/m2, there was a highly-significant difference in patient satisfaction among the different BMI groups (P< 0.000). The significant difference in most of those groups was between the obese group and the other groups. For neck circumference and waist/hip ratio, a significance difference between the normal weight and obese groups (P< 0.000) was found, while for percentage of muscle, the differences were between the overweight and obese groups (P< 0.000). According to BMI groups a highly significant difference in many patient satisfaction domains were found (P< 0.000). These significant differences were between the obese group and non-obese groups for most aspects of patient satisfaction. For patient satisfaction with final appearance, the normal BMI group differed significantly from the overweight BMI group (P=0.013). Additionally, for patient satisfaction with dentist performance and communication, the overweight BMI group showed significantly higher satisfaction than the normal BMI group (P=0.019). Body measurements were correlated negatively with overall patient satisfaction, and positively with satisfaction with prosthesis.

Conclusion: The obese group patients had the lowest rate of patient satisfaction. BMI and other body measurements can be used to predict patient satisfaction with the outcome of dental implant treatment.

背景:牙种植体是目前替代缺失牙齿的首选治疗方式之一,因为它们与天然牙齿最具可比性。即便如此,对这种治疗的满意程度可能因患者的性质而异。本文旨在探讨不同人体测量值与种植体患者满意度之间的关系。方法与材料:采用自填问卷(结构化问题)对接受种植牙治疗的患者进行满意度评价。测量了不同的人体测量值:身高;重量;体重指数(BMI);身体成分;腰围/臀围;还有腰围,臀围和脖子围。结果:总BMI为28.9±4.7 kg/m2,不同BMI组患者满意度差异有显著性意义(P< 0.000)。肥胖组和其他组之间的差异最为显著。颈围、腰臀比在正常体重组与肥胖组之间差异有统计学意义(P< 0.000),肌肉百分比在超重组与肥胖组之间差异有统计学意义(P< 0.000)。BMI组在许多患者满意度方面存在显著差异(P< 0.000)。在大多数患者满意度方面,肥胖组和非肥胖组之间存在显著差异。对于患者对最终外观的满意度,BMI正常组与BMI超重组差异有统计学意义(P=0.013)。此外,在患者对牙医表现和沟通的满意度方面,BMI超重组明显高于BMI正常组(P=0.019)。身体测量与患者总体满意度呈负相关,与假体满意度呈正相关。结论:肥胖组患者满意度最低。BMI和其他身体测量可以用来预测患者对种植牙治疗结果的满意度。
{"title":"Association of Patient Anthropometric Measurements and Dental Implant Treatment.","authors":"Afya Sahib Diab Al-Radha","doi":"10.2147/CCIDE.S406119","DOIUrl":"https://doi.org/10.2147/CCIDE.S406119","url":null,"abstract":"<p><strong>Background: </strong>Dental implants are currently one of the most preferred treatment modalities for replacing missing teeth, as they are the most comparable to natural teeth. Even so, satisfaction with such treatment may differ depending on patient nature. The aim of this article was to examine the relationships between different anthropometric measurements on dental implant patient's satisfaction.</p><p><strong>Methods and material: </strong>Self-administered questionnaire (structured questions) were given to patients who had dental implant treatment to evaluate their satisfaction level with dental-implant treatment. Different anthropometric measurements were taken: body height; weight; body mass index (BMI); body composition; waist/hip ratio; and circumferences at the waist, hip, and neck.</p><p><strong>Results: </strong>The overall BMI was 28.9±4.7 kg/m<sup>2</sup>, there was a highly-significant difference in patient satisfaction among the different BMI groups (P< 0.000). The significant difference in most of those groups was between the obese group and the other groups. For neck circumference and waist/hip ratio, a significance difference between the normal weight and obese groups (P< 0.000) was found, while for percentage of muscle, the differences were between the overweight and obese groups (P< 0.000). According to BMI groups a highly significant difference in many patient satisfaction domains were found (P< 0.000). These significant differences were between the obese group and non-obese groups for most aspects of patient satisfaction. For patient satisfaction with final appearance, the normal BMI group differed significantly from the overweight BMI group (P=0.013). Additionally, for patient satisfaction with dentist performance and communication, the overweight BMI group showed significantly higher satisfaction than the normal BMI group (P=0.019). Body measurements were correlated negatively with overall patient satisfaction, and positively with satisfaction with prosthesis.</p><p><strong>Conclusion: </strong>The obese group patients had the lowest rate of patient satisfaction. BMI and other body measurements can be used to predict patient satisfaction with the outcome of dental implant treatment.</p>","PeriodicalId":10445,"journal":{"name":"Clinical, Cosmetic and Investigational Dentistry","volume":"15 ","pages":"51-61"},"PeriodicalIF":1.8,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/54/86/ccide-15-51.PMC10084864.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9674337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
CBCT Analysis of Edentulous Mandibular Symphysis in Iraqi Patients for Treatment with Implant-Supported Overdentures. Cross-Sectional Single-Center Study. 伊拉克患者种植覆盖义齿治疗无牙下颌联合的CBCT分析。横断面单中心研究。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-01-01 DOI: 10.2147/CCIDE.S410620
Nuhad A Hassan, Aseel S Khazaal Al-Jaboori, Afya Sahib Diab Al-Radha, Maisaa Q Ali, Raya M Albayati

Background: Overdentures supported by dental implants are a useful treatment strategy for patients with edentulous mandibles. The aim of this study was to evaluate certain characteristics of the mandibular symphyseal edentulous cases for dental implant treatment using CBCT; and if it is associated with gender differences.

Methods: Ninety patients (45 females and 45 males) were included in this investigation. A section along the midline of each CBCT image was chosen for the edentulous symphyseal area. Symphysis height, width, and cortical thickness was measured for each patient. Bone density were calculated at four points A two-sample Student's t-test and Pearson correlation were used for statistical analysis.

Results: Males had a considerably greater symphysis height (26.66±6.21 mm) than females (24.07±5.00 mm) (p = 0.02). Similar results were found for bone width; males had greater means than females. In case of cortical bone thickness; males had thicker bone cortex in the buccal region than females (p = 0.01). While the difference in bone density between genders was small. However, a positive relationship was recorded between symphysis height and width.

Conclusion: Height and width of the mandibular symphysis were influenced by gender in edentulous patients, with men showing higher measurements. The reduction of symphyseal height decreased concurrently with the width after teeth were lost, while bone density was maintained in both genders with no difference between them. The lingual cortical bone is significantly thicker than the buccal cortex at the lower part of the symphysis.

背景:种植体支撑覆盖义齿是治疗下颌无牙的有效方法。本研究的目的是利用CBCT评估下颌联合无牙病例在种植牙治疗中的某些特征;以及它是否与性别差异有关。方法:90例患者,其中女45例,男45例。沿每个CBCT图像的中线选择一段作为无牙联合区。测量每位患者的联合高度、宽度和皮质厚度。骨密度在4个点计算,采用两样本Student's t检验和Pearson相关进行统计分析。结果:男性联合高度(26.66±6.21 mm)明显高于女性(24.07±5.00 mm) (p = 0.02)。在骨宽方面也发现了类似的结果;男性比女性拥有更多的财富。如果是皮质骨厚度;男性颊区骨皮质较女性厚(p = 0.01)。而男女之间的骨密度差异很小。联合关节高度与宽度呈正相关。结论:无牙患者下颌联合的高度和宽度受性别的影响,男性的测量值更高。除牙后,骨节高度随宽度减小而减小,骨密度保持不变,两性间无差异。舌皮质骨在联合下部明显比颊皮质厚。
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引用次数: 0
The Role of Asiatic Acid in Preventing Dental Pulp Inflammation: An in-vivo Study. 亚洲酸在预防牙髓炎症中的作用:一项体内研究。
IF 1.8 Q3 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2023-01-01 DOI: 10.2147/CCIDE.S408158
Arlina Nurhapsari, Risya Cilmiaty, Adi Prayitno, Bambang Purwanto, Soetrisno Soetrisno

Purpose: Acute dental pulp inflammation necessitates early treatment to alleviate inflammation and pain. In the inflammatory phase, a substance is required to lower the inflammatory mediators and reactive oxygen species that play a crucial role in that phase. Asiatic acid is a natural triterpene obtained from the Centella asiatica plant with a high antioxidant value. This study examined the effect of Asiatic acid's antioxidant, anti-inflammatory, and antinociceptive properties on dental pulp inflammation.

Methods: The research is an experimental laboratory, with a post-test only with a control group design. The study utilised 40 male Wistar rats weighing 200-250 grams and aged 8-10 weeks. Rats were divided into five groups (control, eugenol, Asiatic Acid 0.5%; 1%; 2% group). Dental pulp inflammation was created in the maxillary incisor after six hours of administration of lipopolysaccharides (LPS). The dental pulp treatment then continued with the administration of eugenol and three different Asiatic acid concentrations (0.5%, 1% and 2%). In the next 72 hours, the teeth were biopsied, and the dental pulp was analysed using the enzyme-linked immunosorbent assay (ELISA) to measure the level of MDA, SOD, TNF-α, beta-endorphins and CGRP. Histopathological examination and the Rat Grimace Scale were utilised to determine the level of inflammation and pain, respectively.

Results: The effect of Asiatic Acid on MDA, TNF-α, and CGRP levels decreased significantly compared to the control group (p=<0.001). On the SOD and beta-endorphin levels, Asiatic acid treatment resulted in a considerable rise (p =<0.001).

Conclusion: Due to its antioxidant, anti-inflammatory, and antinociceptive characteristics, Asiatic acid can reduce inflammation and pain in acute pulp inflammation due to its ability to decrease MDA, TNFα, and CGRP levels while raising SOD and beta-endorphin levels.

目的:急性牙髓炎症需要早期治疗,以减轻炎症和疼痛。在炎症阶段,需要一种物质来降低炎症介质和活性氧,它们在该阶段起着至关重要的作用。亚洲积雪草酸是从积雪草植物中提取的一种天然三萜,具有很高的抗氧化价值。本研究考察了亚细亚酸对牙髓炎症的抗氧化、抗炎、抗伤作用。方法:本研究为实验实验室,只进行后测,采用对照组设计。该研究使用了40只体重200-250克、8-10周龄的雄性Wistar大鼠。大鼠分为5组(对照组、丁香酚、亚细亚酸0.5%;1%;2%组)。脂多糖(LPS)给药6小时后,上颌切牙产生牙髓炎症。然后继续使用丁香酚和三种不同浓度的亚硫酸(0.5%,1%和2%)进行牙髓治疗。在接下来的72小时内,对牙齿进行活检,用酶联免疫吸附法(ELISA)分析牙髓,测定MDA、SOD、TNF-α、β -内啡肽和CGRP的水平。组织病理学检查和大鼠鬼脸量表分别用于确定炎症和疼痛的水平。结果:与对照组相比,亚细亚酸对MDA、TNF-α和CGRP水平的影响显著降低(p=结论:亚细亚酸具有抗氧化、抗炎和抗损伤的特点,其作用机制是降低MDA、TNF-α和CGRP水平,同时升高SOD和-内啡肽水平,从而减轻急性牙髓炎症的炎症和疼痛。
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引用次数: 0
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Clinical, Cosmetic and Investigational Dentistry
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