Amir H. Sohail, Samuel L. Flesner, Mohammed A. Quazi, Ahmed Sami Raihane, Soban Maan, Aman Goyal, Dushyant Singh Dahiya, Hassam Ali, Yassine Kilani, Fouad Jaber, Saqr Alsakarneh, Manesh Kumar Gangwani, Abu Baker Sheikh, Asad Ullah, Jennifer Whittington, Shailandra Singh
Aims
Anal cancer, despite its rarity, is a matter of serious concern in the United States, with an uptrend in recent years and marked racial disparities in mortality rates. The aim of this work was to investigate anal cancer mortality trends and sex race disparities in the United States from 1999 to 2020.
Method
This is a retrospective study using data from the CDC WONDER database (1999–2020). We investigated deaths attributed to anal cancer, identified by the ICD-10 code C21.1, and excluded individuals aged 14 years and under. The Mann–Kendall trend test was used to investigate temporal trends and a t-test was used to compare continuous variables.
Results
Both male and female age-adjusted mortality attributed to anal cancer increased significantly during the study period across all subgroups, including race (Black and White), US Census region (Northeast, Midwest, South and West) and age (15–64 and ≥65 years) (p < 0.001 for all comparisons). For each subgroup, women demonstrated significantly higher rates of mortality than men, except in the Black population, where Black men had higher rates than Black women (0.40 vs. 0.29, p < 0.001). Additionally, Black men had significantly higher mean mortality rates than White men (0.40 vs. 0.27, p < 0.001). The highest rates of anal cancer mortality were among geriatric individuals, especially women aged ≥65 years, at 1.18 per 100 000.
Conclusion
The rise in anal cancer mortality and racial and sex disparities present a significant challenge for healthcare providers and policy makers. Further studies are required to devise evidence-based strategies to effectively tackle this challenge.
目的肛门癌尽管罕见，但在美国却引起了严重关注，近年来呈上升趋势，而且死亡率存在明显的种族差异。本研究旨在调查 1999 年至 2020 年美国肛门癌死亡率趋势和性别种族差异。方法这是一项回顾性研究，使用的数据来自美国疾病预防控制中心 WONDER 数据库（1999-2020 年）。我们调查了因肛门癌死亡的病例（以ICD-10代码C21.1识别），并排除了14岁及以下的人群。结果在研究期间，男性和女性年龄调整后的肛门癌死亡率在所有亚组中均显著上升，包括种族（黑人和白人）、美国人口普查地区（东北部、中西部、南部和西部）和年龄（15-64 岁和≥65 岁）（所有比较的 p 均为 0.001）。在每个亚组中，女性的死亡率都明显高于男性，但黑人除外，黑人男性的死亡率高于黑人女性（0.40 vs. 0.29，p < 0.001）。此外，黑人男性的平均死亡率明显高于白人男性（0.40 vs. 0.27，p <0.001）。肛门癌死亡率最高的人群是老年人，尤其是年龄≥65 岁的女性，每 10 万人中有 1.18 人死亡。需要进一步开展研究，以制定循证策略，有效应对这一挑战。
{"title":"Emerging trends and demographic disparities in anal cancer mortality across the United States census regions: An analysis of National Center for Health Statistics mortality data","authors":"Amir H. Sohail, Samuel L. Flesner, Mohammed A. Quazi, Ahmed Sami Raihane, Soban Maan, Aman Goyal, Dushyant Singh Dahiya, Hassam Ali, Yassine Kilani, Fouad Jaber, Saqr Alsakarneh, Manesh Kumar Gangwani, Abu Baker Sheikh, Asad Ullah, Jennifer Whittington, Shailandra Singh","doi":"10.1111/codi.17167","DOIUrl":"10.1111/codi.17167","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Anal cancer, despite its rarity, is a matter of serious concern in the United States, with an uptrend in recent years and marked racial disparities in mortality rates. The aim of this work was to investigate anal cancer mortality trends and sex race disparities in the United States from 1999 to 2020.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>This is a retrospective study using data from the CDC WONDER database (1999–2020). We investigated deaths attributed to anal cancer, identified by the ICD-10 code C21.1, and excluded individuals aged 14 years and under. The Mann–Kendall trend test was used to investigate temporal trends and a <i>t</i>-test was used to compare continuous variables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Both male and female age-adjusted mortality attributed to anal cancer increased significantly during the study period across all subgroups, including race (Black and White), US Census region (Northeast, Midwest, South and West) and age (15–64 and ≥65 years) (<i>p</i> < 0.001 for all comparisons). For each subgroup, women demonstrated significantly higher rates of mortality than men, except in the Black population, where Black men had higher rates than Black women (0.40 vs. 0.29, <i>p</i> < 0.001). Additionally, Black men had significantly higher mean mortality rates than White men (0.40 vs. 0.27, <i>p</i> < 0.001). The highest rates of anal cancer mortality were among geriatric individuals, especially women aged ≥65 years, at 1.18 per 100 000.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The rise in anal cancer mortality and racial and sex disparities present a significant challenge for healthcare providers and policy makers. Further studies are required to devise evidence-based strategies to effectively tackle this challenge.</p>\u0000 </section>\u0000 </div>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"26 11","pages":"1913-1921"},"PeriodicalIF":2.9,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142249291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Transverse colectomy using the RoboLap cooperative technique for mid-transverse colon cancer – A Video Vignette","authors":"Takehito Yamamoto, Meiki Fukuda, Reo Nakano, Yoshihisa Okuchi, Kojiro Taura, Hiroaki Terajima","doi":"10.1111/codi.17162","DOIUrl":"10.1111/codi.17162","url":null,"abstract":"","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"26 11","pages":"2012-2013"},"PeriodicalIF":2.9,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142183489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carlo Alberto Manzo, Michela Faccioli, Caterina Baldi, Leonardo Lorusso, Gianluca Matteo Sampietro
{"title":"Proctectomy with IPAA for rectal dysplasia after ileorectal anastomosis in Crohn's disease: A video vignette","authors":"Carlo Alberto Manzo, Michela Faccioli, Caterina Baldi, Leonardo Lorusso, Gianluca Matteo Sampietro","doi":"10.1111/codi.17171","DOIUrl":"10.1111/codi.17171","url":null,"abstract":"","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"26 11","pages":"2015-2016"},"PeriodicalIF":2.9,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142183488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Step-by-step approach in laparoscopic total intersphincteric resection in rectal cancer—A video vignette","authors":"Danusorn Paekaittiwong, Phadungkiat Tipmanee","doi":"10.1111/codi.17166","DOIUrl":"10.1111/codi.17166","url":null,"abstract":"","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"26 10","pages":"1860-1861"},"PeriodicalIF":2.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142183496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Blazeby JM, Murkin C, Rooshenas L, Elliott D, Avery K, Chalmers K et al. Development and pilot testing of a patient-reported outcome measure to assess symptoms of parastomal hernia. Colorectal Dis. 2024;26:364–70. https://doi.org/10.1111/codi.16850
The funding statement for this article was missing. Funding information (Medical Research Council grants G0800800 and MR/K025643/1).
{"title":"Correction to ‘Development and pilot testing of a patient reported outcome measure to assess symptoms of parastomal hernia’","authors":"","doi":"10.1111/codi.17161","DOIUrl":"10.1111/codi.17161","url":null,"abstract":"<p>Blazeby JM, Murkin C, Rooshenas L, Elliott D, Avery K, Chalmers K et al. Development and pilot testing of a patient-reported outcome measure to assess symptoms of parastomal hernia. <i>Colorectal Dis</i>. 2024;26:364–70. https://doi.org/10.1111/codi.16850</p><p>The funding statement for this article was missing. Funding information (Medical Research Council grants G0800800 and MR/K025643/1).</p><p>We apologize for this error.</p>","PeriodicalId":10512,"journal":{"name":"Colorectal Disease","volume":"26 10","pages":"1864"},"PeriodicalIF":2.9,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/codi.17161","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142183495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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