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Type 1 Tympanoplasty by Interlay Technique for Management of Tympanic Membrane Perforation 夹层成形术治疗1型鼓膜穿孔
Pub Date : 2023-02-19 DOI: 10.3329/cbmj.v12i1.64303
B. K. Biswas, Manjurul Karim Khan, Subir Gupta
Tympanic membrane is the partition between the external ear and middle layer which is a vital component of the human ear. Neglected or maltreated earache, ear discharge and trauma lead to perforation of tympanic membrane. Tympanoplasty is the surgical procedure performed to repair a perforated tympanic membrane, with/without reconstruction of the ossicles, with the aim of preventing reinfection and restoring hearing ability. Type 1 tympanoplasty is the simple closure of the tympanic membrane perforation. To study the outcome of type 1 tympanoplasty operation by interlay technique, a descriptive longitudinal study was conducted among 200 patients in Community Based Medical College Hospital and in private clinics of Mymensingh from January 2012 to December 2021. Our inclusion criteria was population of age ranging from 15 to 55 yrs of both sexes having dry central perforation for at least 6 weeks and exclusion criteria was patient with active stage of chronic suppurative otitis media (CSOM), ossicular discontinuity, sensory neural hearing loss. Data was analyzed by SPSS version 20.0. Prevalence of taking graft was 96.00%. Measured by difference of preoperative air bone gap (ABG) and postoperative ABG of 15 decibel (dB) hearing improvement rate was 90%. Complication was minimal (1%). The complication was infection due to non-compliance with postoperative advice and treatment. Type 1 tympanoplasty done by interlay technique has excellent results both in terms of graft taken and hearing improvement with minimal complications. CBMJ 2023 January: Vol. 12 No. 01 P: 67-72
鼓膜是外耳和中间层之间的隔膜,是人耳的重要组成部分。忽视或虐待耳痛,耳漏和外伤导致鼓膜穿孔。鼓室成形术是修复穿孔鼓膜的外科手术,伴有或不伴有小骨重建,目的是防止再感染和恢复听力。1型鼓室成形术是对鼓膜穿孔进行简单的封闭。为了研究夹层技术1型鼓室成形术的效果,我们对2012年1月至2021年12月在Mymensingh社区医学院医院和私人诊所的200例患者进行了描述性纵向研究。我们的纳入标准是年龄在15 - 55岁之间的男性和女性,有至少6周的干性中耳炎,排除标准是慢性化脓性中耳炎(CSOM)活动期、听骨不连续、感觉神经性听力损失的患者。数据分析采用SPSS 20.0版本。受贿率为96.00%。通过术前气骨间隙(ABG)与术后ABG的差异测量,15分贝(dB)的听力改善率为90%。并发症极少(1%)。并发症是不遵守术后建议和治疗引起的感染。采用夹层技术进行的1型鼓室成形术在移植物移植和听力改善方面均有良好的效果,并发症最少。中华医学杂志2023年1月12期01期P: 67-72
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引用次数: 0
Mothers’ Experience and Perceived Barriers to Practice Healthy Feeding to Their School Going Children 母亲对学龄儿童实行健康喂养的经验和感知障碍
Pub Date : 2023-02-19 DOI: 10.3329/cbmj.v12i1.64364
Tunazzina Shahrin, Bijoy Kumer Paul, S. Sharmin, Munira Begum, Nusrat Jahan, Farzana Nusrat, Moyeedur Rahman
A cross-sectional study was conducted between January and December of 2018 in some randomly selected schools under Dhaka City Corporation, Bangladesh, to examine mothers’ experience and their perceived barriers to practice healthy feeding to their school going children. We adopted convenient sampling technique. A total of 120 mothers participated in this study who had children aged between six and eight years. A pre-tested, semi-structured questionnaire was used for data collection. Questionnaire was formatted in both Bangla and English language. However, the participants chose Bangla version for filling up the survey questionnaire. A modified Likert’s scale was used. Socio-demographic variables, mothers’ feeding practice and perceived barriers were analysed using descriptive statistics. 58.2% of the participants belonged to 30-35 years age group, while 41.8% to 36-40 years age group. Among them, higher secondary passed 3.4%, while 35.3% had their university graduation, and 61.3% completed postgraduation. 6.7% had poor economic status, while 73.3% were semi-elite and 20% were from elite income group. Among them, 75% were Muslim, 14.2% Hindu, 7.5% Christian and 3.3% Buddhist. 21.7% of the mothers found availability of healthy food as 'very easy' and 66.7% found it 'easy', while 9.2% found it 'difficult'; only 2.5% found it 'very difficult'. Only 11.6% of the mothers found preparation of healthy meal inconvenient, while 71.7% found it convenient and 16.7% found it very convenient. Regarding taste of a healthy meal, 2.5% reported as 'very monotonous', 37.5% as 'monotonous', 54.2% reported as 'charming' and only 5.8% stated it as 'very charming'. Preparation cost of a healthy meal was reported as costly by only 15.8% of the mothers, while cost effective by 76.7%, and very cost effective by the rest 7.5%. 42.4% of the mothers stated that their children have the habits of taking meal sitting with the family members, while 48.8% were fed while watching TV, and 8.8% reported that they fed their children while they were playing. Only 37.5% of mothers reported that their children found it pleasant taking healthy food. Regarding time spent on feeding the children, 17.5% stated 'very time consuming', while 68.3% stated 'time consuming', and only 14.2% found it 'timesaving'. Only 20.8% of mothers reported that they could conveniently feed their children healthy food. Difficulties experienced by the mothers were strong aversion (15.8%), fast food preference (22.5%), varieties of food preference (61.7%). CBMJ 2023 January: Vol. 12 No. 01 P: 93-98
2018年1月至12月期间,在孟加拉国达卡市公司(Dhaka City Corporation)下随机选择的一些学校进行了一项横断面研究,以检查母亲的经历以及她们认为的为学龄儿童实行健康喂养的障碍。我们采用了方便的抽样技术。共有120名母亲参与了这项研究,她们的孩子年龄在6到8岁之间。采用预先测试的半结构化问卷进行数据收集。问卷以孟加拉文和英文两种格式填写。然而,参与者选择孟加拉语版本填写调查问卷。采用改良的李克特量表。使用描述性统计分析社会人口变量、母亲喂养做法和感知障碍。30-35岁年龄组占58.2%,36-40岁年龄组占41.8%。其中,高中毕业3.4%,大学毕业35.3%,研究生毕业61.3%。6.7%的人经济状况不佳,73.3%的人属于半精英阶层,20%的人来自精英收入群体。其中75%是穆斯林,14.2%是印度教徒,7.5%是基督教徒,3.3%是佛教徒。21.7%的母亲认为获得健康食品“非常容易”,66.7%认为“容易”,9.2%认为“困难”;只有2.5%的人认为“非常困难”。只有11.6%的妈妈认为准备健康餐不方便,71.7%的妈妈认为方便,16.7%的妈妈认为非常方便。关于健康饮食的味道,2.5%的人认为“非常单调”,37.5%的人认为“单调”,54.2%的人认为“迷人”,只有5.8%的人认为“非常迷人”。只有15.8%的母亲认为健康膳食的准备成本昂贵,而76.7%的母亲认为成本有效,其余7.5%的母亲认为非常具有成本效益。42.4%的母亲表示自己的孩子有和家人坐在一起吃饭的习惯,48.8%的母亲在看电视的时候喂孩子,8.8%的母亲在孩子玩耍的时候喂孩子。只有37.5%的母亲报告说,她们的孩子觉得吃健康食品很愉快。17.5%的人认为“非常耗时”,68.3%的人认为“耗时”,只有14.2%的人认为“省时”。只有20.8%的母亲报告说,她们可以方便地给孩子喂健康食品。母亲的困难表现为强烈厌恶(15.8%)、快餐偏好(22.5%)、食物偏好种类(61.7%)。中华医学杂志2023年1月12期01期P: 93-98
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引用次数: 0
Role of Bronchoalveolar Lavage (BAL) Gene Xpert in Diagnosis of PTB in Sputum Smear Negative Patients 支气管肺泡灌洗(BAL)基因Xpert在痰涂片阴性患者PTB诊断中的作用
Pub Date : 2023-02-19 DOI: 10.3329/cbmj.v12i1.64292
KM Monjurul Alom, Mirza Mohammad Idris Ali, Md Jakaria Mahmud, Mohiuddin Ahmed
The aim of this study was to assess the diagnostic efficacy of Xpert MTB/RIF assay in bronchoalveolar lavage (BAL) in the diagnosis of pulmonary tuberculosis in sputum-smear negative patients. This observational case series study was conducted in a tertiary base institute of Bangladesh from July 2017 to June 2019. All patients with suspected pulmonary tuberculosis who were sputum-smear negative, irrespective of age and gender were included in this study. BAL fluid thus obtained and examined the smear for acid fast bacilli (AFB) and Xpert MTB/RIF assay. The sensitivity, specificity and accuracy values were calculated for smear AFB and Xpert MTB/RIF assay. Xpert MTB/RIF was identified 33 (36.7%) of 90 patients on bronchoalveolar lavage fluid in the final analysis. AFB Fluid culture was positive in 28 (31.2%) cases. The sensitivity and specificity of Xpert MTB/RIF assay was 85.7%, and 85.5% respectively. The positive likelihood ratio was 5.90, and the negative likelihood ratio was 0.167. The accuracy was 85.56%. Xpert MTB/RIF on BAL fluid can be recommended as a fruitful diagnostic tool for mycobacterium pulmonary tuberculosis especially in sputum smear negative, and culture negative patients. CBMJ 2023 January: Vol. 12 No. 01 P: 60-66
本研究的目的是评估Xpert支气管肺泡灌洗(BAL) MTB/RIF检测对痰涂片阴性患者肺结核的诊断效果。该观察性病例系列研究于2017年7月至2019年6月在孟加拉国的一个三级基地研究所进行。所有痰涂片阴性的疑似肺结核患者,不论年龄和性别,均纳入本研究。由此获得BAL液并检测抗酸杆菌(AFB)涂片和Xpert MTB/RIF试验。计算涂片AFB和Xpert MTB/RIF检测的敏感性、特异性和准确性。90例支气管肺泡灌洗液患者中有33例(36.7%)被确定为MTB/RIF。AFB液体培养阳性28例(31.2%)。Xpert MTB/RIF检测的灵敏度和特异性分别为85.7%和85.5%。阳性似然比为5.90,阴性似然比为0.167。准确率为85.56%。对BAL液的Xpert MTB/RIF可推荐作为肺结核分枝杆菌的有效诊断工具,特别是在痰涂片阴性和培养阴性患者中。中华医学杂志2023年1月12期01期60-66页
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引用次数: 0
Meconium-Stained Amniotic Fluid and Its Perinatal Feto-maternal Outcome 羊水粪染色及其围产期胎母结局
Pub Date : 2022-08-17 DOI: 10.3329/cbmj.v11i2.61228
Md Mahbubur Rahman, A. Amin, Md.Abdul Quader
Meconium Stained Amniotic Fluid is associated with increased risk of operative delivery or caesarean section and increased rate of neonatal resuscitation, morbidity and mortality. A hospital-based prospective, observational study was conducted in the Obstetrics & Gynecology Department, NICU and Neonatal Ward of Naval Base Hospital, a tertiary care hospital of Bangladesh Navy, Chattogram, Bangladesh, between January 2020 and December 2021. A semi-structured questionnaire was prepared for both case and control group. 182 cases were enrolled as case and another 182 cases were as control. Antenatal checkup was significantly less in cases (p<0.05). Mean weight was 2.8±0.4 Kg in cases and in control 2.7±0.5 Kg (p<0.01). Mean fetal heart rate were 140±10.5 beats/min in cases and in control 135.7±7.2 beats/min (p<0.01). Apgar scores at 1st minute and fifth minutes were significantly lower in cases (7±1.4 and 8.2±1.2 respectively) in comparison to control (7.5±0.3 and 9.2±1.1 respectively). Obstetric outcome of labor, that is mode of delivery was significantly dictated by the presence of MSAF. There were more than half (57.1%) of the cases were having grade three MSAF, whereas grade one and grade two were 14.8% and 28% respectively. Perinatal asphyxia, 5 min APGAR score <7, oropharyngeal suction needed, EONS, MAS, admission in NICU/Neonatal ward and neonatal death all were significantly higher in MASF group. MSAF is associated with increased need for neonatal resuscitation, higher risk of perinatal asphyxia, MAS, hospital admission and mortality for fetus and higher risk for operative delivery. CBMJ 2022 July: vol. 11 no. 02 P: 114-119
羊水粪染色与手术分娩或剖宫产风险增加、新生儿复苏率、发病率和死亡率增加有关。2020年1月至2021年12月,在孟加拉国海军三级医院海军基地医院妇产科、新生儿重症监护室和新生儿病房进行了一项以医院为基础的前瞻性观察研究。对病例组和对照组分别进行半结构化问卷调查。182例作为病例,182例作为对照。产前检查明显少于对照组(p<0.05)。患者平均体重为2.8±0.4 Kg,对照组为2.7±0.5 Kg (p<0.01)。平均胎心率为140±10.5次/min,对照组为135.7±7.2次/min (p<0.01)。第1分钟和第5分钟Apgar评分(分别为7±1.4和8.2±1.2)明显低于对照组(分别为7.5±0.3和9.2±1.1)。分娩的产科结果,即分娩方式是由MSAF的存在显着决定的。超过一半(57.1%)的病例为三级MSAF,一级和二级MSAF分别为14.8%和28%。围产儿窒息、5 min APGAR评分<7分、需要口咽吸痰、EONS、MAS、NICU/新生儿病房入院及新生儿死亡均显著高于MASF组。MSAF与新生儿复苏需求增加、围产期窒息、MAS、住院和胎儿死亡率增加以及手术分娩风险增加有关。《中国医学杂志》2022年7月第11期[02:14 . 119
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引用次数: 0
Dermatoglyphic Assessment in Male Down Syndrome 男性唐氏综合症的皮肤纹评估
Pub Date : 2022-08-17 DOI: 10.3329/cbmj.v11i2.61284
R. Parveen, M. Rahman, Mahmud Ahmed, Md. Ashraful Azim, Zeenatul Momena, Mohammad Nahid Salman
Down syndrome (DS) is the most common chromosomal disorder which causes intellectual disability. It is mainly because of the presence of extra copy of chromosome number 21. Dermatoglyphic has been well established as a diagnostic aid in number of diseases having hereditary basis. Dermatoglyphic data was obtained by the use of ink and prints on a paper. This cross-sectional, analytical type of study was performed at the Department of Anatomy, Dhaka Medical College, Dhaka from January 2017 to December 2017 on 40 Down syndrome subjects (age ranged from 6 to 16) selected from Society for the Welfare of the Intellectually Disabled, Bangladesh (SWID, Bangladesh) and Down Syndrome Society of Bangladesh (DSS) and compared with 40 controls for the establishment of comparison between two groups. Dermatoglyphic prints were used to evaluate the difference in „atd‟ „dat‟ „adt‟ angles and pattern intensity between the control and the DS individuals. The results showed that „atd‟ angle was significantly higher (p<0.05) in Down males than the controls. The dactylography study also revealed lower „dat‟ „adt‟ angles (p<0.05) and pattern intensity (p<0.001) in both hands of Down syndrome group. This method is non-invasive and cost effective. The observed changes in the „atd‟ „dat‟ and „adt‟ angles plus the patterns intensity in the dermatoglyphic study proved that this simple technique could be a valuable tool for selecting individuals of DS for cytogenetic analysis. CBMJ 2022 July: vol. 11 no. 02 P: 144-151
唐氏综合症(DS)是最常见的导致智力残疾的染色体疾病。这主要是由于21号染色体存在额外的拷贝。皮肤印记已被很好地确立为许多具有遗传基础的疾病的诊断援助。皮纹数据是通过在纸上使用墨水和印刷品获得的。这项横断面分析型研究于2017年1月至2017年12月在达卡医学院解剖学系对40名唐氏综合征受试者(年龄从6岁到16岁不等)进行了研究,这些受试者分别来自孟加拉国智障人士福利协会(SWID, Bangladesh)和孟加拉国唐氏综合征协会(DSS),并与40名对照组进行了比较,以建立两组之间的比较。采用皮纹印评价对照与DS个体在“atd”、“data”、“adt”角度和图案强度上的差异。结果表明,唐氏雄性的“atd”角显著高于对照组(p<0.05)。指型学研究还显示,唐氏综合征组双手的“数据”“adt”角度(p<0.05)和模式强度(p<0.001)较低。该方法无创且成本有效。观察到的“atd”、“dat”和“adt”角度的变化加上纹纹研究的模式强度证明,这种简单的技术可以作为选择DS个体进行细胞遗传学分析的有价值的工具。《中国医学杂志》2022年7月第11期[02:44 . 151
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引用次数: 0
Serum Zinc Level in Children Suffering from Type 1 Diabetes Mellitus and Its Relationship with Glycemic Control: An Experience from A Tertiary Level Specialized Diabetic Hospital in Bangladesh 1型糖尿病患儿血清锌水平及其与血糖控制的关系:孟加拉国一家三级糖尿病专科医院的经验
Pub Date : 2022-08-17 DOI: 10.3329/cbmj.v11i2.61223
Shawana Haque, M. Mozaffor, M. Mahmud, M. Muttalib
A cross-sectional study was conducted in the Department of Biochemistry and Molecular Biology of Bangladesh Institute of Research and Rehabilitation in Diabetes, Endocrine and Metabolic Disorders (BIRDEM), Dhaka, Bangladesh, between July 2016 and June 2017, to evaluate serum zinc level and its relationship with glycemic control in type 1 diabetic children. A total of 160 participants (all aged between 1 and 18 years) were selected from the outpatient department (OPD) of BIRDEM General Hospital-2, Dhaka – 80 type 1 diabetic children as cases and 80 apparently healthy children as controls. We measured anthropometric parameters all study subjects. Serum zinc level was assessed using colorimetric method. Fasting plasma glucose level was estimated using enzymatic glucose-oxidase method. Glycemic control was evaluated through estimation of HbA1c using a high-performance liquid chromatographic method. The mean serum zinc levels were significantly lower in patient with type 1 DM compared to control (72.5±16.5 vs. 82.4±13.3 μg/dl; P<0.001). Lower levels of zinc were found in subjects with poor glycemic control compared to good glycemic control (62.8±14.6 vs. 78.8±14.6 μg/dl; P<0.001). Moreover, serum zinc levels were significantly lower in patients who have duration of diabetes mellitus for 5 years or more (P<0.05). To summarize, serum zinc level is lower in type 1 diabetic children in comparison to its healthy counterpart and this lower zinc level is strongly associated with poor glycemic control which may potentially contribute to the early development of diabetic complications in children. CBMJ 2022 July: vol. 11 no. 02 P: 80-85
2016年7月至2017年6月,在孟加拉国达卡的孟加拉国糖尿病、内分泌和代谢疾病研究与康复研究所(BIRDEM)生物化学和分子生物学学系进行了一项横断面研究,以评估1型糖尿病儿童血清锌水平及其与血糖控制的关系。选取来自达卡BIRDEM第二总医院门诊部(OPD)的160名参与者(年龄均在1 ~ 18岁之间),其中80名1型糖尿病儿童为病例,80名表面健康儿童为对照组。我们测量了所有研究对象的人体测量参数。采用比色法测定血清锌水平。采用酶促葡萄糖氧化酶法测定空腹血糖水平。采用高效液相色谱法测定糖化血红蛋白,评估血糖控制情况。1型糖尿病患者的平均血清锌水平明显低于对照组(72.5±16.5∶82.4±13.3 μg/dl;P < 0.001)。与血糖控制良好的受试者相比,血糖控制较差的受试者锌水平较低(62.8±14.6 vs 78.8±14.6 μg/dl;P < 0.001)。糖尿病病程5年及以上的患者血清锌水平明显降低(P<0.05)。总之,1型糖尿病儿童的血清锌水平比健康儿童低,而这种低锌水平与血糖控制不良密切相关,这可能会导致儿童糖尿病并发症的早期发展。《中国医学杂志》2022年7月第11期[02:80 . 85
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引用次数: 0
Measurement of the Breadth of the Thyroid Lamina in A Bangladeshi Population by Dissection Method 用解剖法测量孟加拉人群甲状腺层的宽度
Pub Date : 2022-08-17 DOI: 10.3329/cbmj.v11i2.61282
A. Ara, Zubaida Gulshan Kazi Ara, T. Begum, Dilruba Afrose Mili, K. Naher
A cross-sectional, descriptive study was done to determine the breath of the thyroid lamina and the differences in its values in respect of age and sex in Bangladeshi cadavers. A total 60 postmortem human larynges were collected between October 2008 and March 2009. Among those, 45 (male 23 and female 22) were collected from unknown dead bodies (aged between 9 and 60 years) under autopsy in the mortuary of Department of Forensic Medicine of Mymensingh Medical College, while the other 15 (male 6 and female 9) were collected from stillborn babies of viable age (28 to 40 weeks of gestation) in the Department of Obstetrics & Gynaecology of Mymensingh Medical College Hospital, Mymensingh, Bangladesh. The breath of thyroid lamina was measured from laryngeal prominence to the posterior margins of lamina at its transverse plane using slide calipers and differences were observed in between age groups and sexes. The mean±SD breadth of thyroid lamina was found 12.40±1.30 mm in group A (from 28 to 40 weeks of gestation) ranging between 9 and 14 mm, while 26.19±3.69 mm in group B (from 9 to 16 years) ranging between 21 and 35 mm, and 30.76±4.17 mm in group C (from 17 to 60 years) with a range of 24 to 38 mm. The mean breadth of thyroid lamina was highest in age group C (30.76 mm) and was lowest in age group A (12.40 mm). The mean difference of breadth of thyroid lamina between group A & B, A & C and B & C were statistically significant (P=0.000). The breadth of thyroid lamina was found higher in male (32.70±3.96 mm) than that of female (28.00±2.69 mm) in Group C and the difference was statistically significant (p=0.001). Our study revealed that the breadth of thyroid lamina is greater in adult male than female and overall, the value increases with age. CBMJ 2022 July: vol. 11 no. 02 P: 131-135
进行了一项横断面描述性研究,以确定孟加拉国尸体中甲状腺层的呼吸及其值在年龄和性别方面的差异。在2008年10月至2009年3月期间共收集了60个死后的人类喉部。其中45例(男23例,女22例)是在Mymensingh医学院法医学系太平间尸检时从身份不明的尸体(年龄在9至60岁之间)中收集的,另外15例(男6例,女9例)是在孟加拉国Mymensingh医学院附属医院妇产科从可存活年龄(妊娠28至40周)的死产婴儿中收集的。用滑动卡尺测量甲状腺层的呼吸,从喉突到层后缘的横切面,观察不同年龄组和性别之间的差异。A组(28 ~ 40周)甲状腺层平均±SD宽度为12.40±1.30 mm,范围为9 ~ 14 mm; B组(9 ~ 16岁)甲状腺层平均宽度为26.19±3.69 mm,范围为21 ~ 35 mm; C组(17 ~ 60岁)甲状腺层平均宽度为30.76±4.17 mm,范围为24 ~ 38 mm。甲状腺层平均宽度C组最高(30.76 mm), A组最低(12.40 mm)。A、B组、A、C、B、C组甲状腺层宽度平均差异有统计学意义(P=0.000)。C组男性甲状腺层宽度(32.70±3.96 mm)高于女性(28.00±2.69 mm),差异有统计学意义(p=0.001)。我们的研究表明,成年男性的甲状腺层宽度大于女性,并且随着年龄的增长而增加。《中国医学杂志》2022年7月第11期[p]: 131-135
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引用次数: 0
Correlation between Sociodemographic Variables and OncoE6 Cervical Swab Test Positive Cases 社会人口学变量与OncoE6宫颈拭子试验阳性病例的相关性
Pub Date : 2022-08-17 DOI: 10.3329/cbmj.v11i2.61285
Faijun Nahar, Md. Akram Hossain, S. K. Paul, S. Khatun, G. R. Bhuiyan, S. Nasreen, Salma Ahmed, N. Haque
A cross-sectional, observational study was conducted to determine the relationship between sociodemographic variables and the development of cervical cancer through detection of detection of HPVE6 oncoprotein. A total of 47 endocervical swabs were collected from colposcopy clinic under the Department of Obstetrics & Gynaecology, Mymensingh Medical College, Mymensingh, Bangladesh, from January to December of 2015. Laboratory work was done in the Department of Microbiology of the same institution. E6 strip test is an immunochromatographic test based on detection of HPV-E6 oncoprotein in cervical swab samples. The swab specimen was treated with lysis solution and conditioning solution. Then the specimen solution was clarified by centrifugation. After that the sample solution was transferred into the detector mAb vial, wash solution vial, and finally, into developing solution vial. The test unit was then placed on a reading guide. Positive result was indicated by the appearance of purple colored test line. Out of 47 specimens, 21 (44.68%) were OncoE6 positive. Among those 21 positive cases, 19 (90.48%) were HPV-16 and 2 were (9.52%) HPV-18. Out of 11 histologically diagnosed CIN I cases, 1 (9.09%) case came out as positive. However, there were no positive cases by oncoE6 cervical swab test in CIN II and CINIII categories. Among histopathologically confirmed 22 cervical carcinoma cases, 20 (90.90%) came out as positive through this test. The results were compared with sociodemographic variables. OncoE6 is more common among ≥50 age group, and who got married before 18 years, and in multiparous women (P<0.05). Cervical cancer prevention services should be strengthen including health education, OncoE6 screening, and Anti-HPV vaccination. CBMJ 2022 July: vol. 11 no. 02 P: 152-157
通过检测HPVE6癌蛋白,开展了一项横断面观察性研究,以确定社会人口学变量与宫颈癌发生的关系。于2015年1月至12月在孟加拉国迈门辛格医学院妇产科阴道镜诊所收集宫颈内膜拭子47份。实验室工作在同一机构的微生物学系完成。E6条带试验是一种基于宫颈拭子样本中HPV-E6癌蛋白检测的免疫层析试验。拭子标本分别用裂解液和调理液处理。然后将标本溶液离心澄清。之后,将样品溶液转移到检测器单抗瓶、洗涤液瓶中,最后转移到显影液瓶中。然后将测试单元放在阅读指南上。紫色试验线的出现表明阳性结果。47例标本中OncoE6阳性21例(44.68%)。其中HPV-16型19例(90.48%),HPV-18型2例(9.52%)。11例组织学诊断为CIN的病例中,1例(9.09%)为阳性。然而,在cinii和CINIII类别中,宫颈拭子检查没有阳性病例。病理证实的22例宫颈癌中,20例(90.90%)阳性。将结果与社会人口学变量进行比较。OncoE6在≥50岁年龄组、18岁前结婚者和多产妇女中较常见(P<0.05)。应加强宫颈癌预防服务,包括健康教育、OncoE6筛查和抗hpv疫苗接种。《中国医学杂志》2022年7月第11期[p]: 152-157
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引用次数: 0
Position and Attachment of the Babies During Breastfeeding: A Comparison of Before and After Counselling the Mothers 母乳喂养中婴儿的体位与依恋:母亲咨询前后的比较
Pub Date : 2022-08-17 DOI: 10.3329/cbmj.v11i2.61226
Shamsi Sumaiya Ashique, Ainun Afroze, R. Rana, Habiba Jesmin, Shabnam Sharmin, S. Sharmin
A prospective, observational study was conducted in the Department of Obstetrics & Gynaecology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, between July 2008 and January 2009 to compare position and attachment of the babies during breastfeeding before and after counselling the mothers. Our study samples include 100 healthy mothers and 100 term healthy babies. Initially, all the mothers and babies were observed for their position and attachment during breastfeeding within 24 hours of the delivery and documented in a standard data sheet. Then the mothers were shown the wall chart of nursing mothers and breastfeeding manual and taught practically by the investigators. Mothers were requested to come after 15 days for follow-up visit so that they become physically fit by that time and improve their skills. At follow-up visit, documentation of the position and attachment during breastfeeding was done in the data sheet. Comparison of each of the components of positioning and attachment was done with first observation (i.e., within 24 hours of the birth of the baby) and follow-up observation (i.e., after 15 days). The mean age of the mothers was 29.40±4.71 years. In all components of the position and attachment of the babies, the difference between before and after counselling the mothers was statistically significant (P<0.05). Similarly, in all signs of effective sucking, the difference was also statistically significant between before and after counselling (P<0.05) except for the sign of oxytocin reflex noticed by the mother (P>0.05). CBMJ 2022 July: vol. 11 no. 02 P: 102-107
2008年7月至2009年1月,在孟加拉国达卡的Bangabandhu Sheikh Mujib医科大学(BSMMU)妇产学系进行了一项前瞻性观察研究,比较母乳喂养期间婴儿在向母亲提供咨询之前和之后的姿势和依恋。我们的研究样本包括100名健康母亲和100名足月健康婴儿。最初,在分娩后24小时内观察所有母亲和婴儿在母乳喂养期间的姿势和依恋,并记录在标准数据表中。然后给母亲看母乳喂养挂图和母乳喂养手册,并由调查人员进行实际教学。母亲们被要求在15天后来进行随访,以便她们在那时身体健康并提高她们的技能。在随访中,在数据表中记录了母乳喂养期间的位置和依恋。通过首次观察(即婴儿出生后24小时内)和随访观察(即15天后)对定位和附着各组成部分进行比较。产妇平均年龄29.40±4.71岁。在婴儿的体位和依恋的各个组成部分中,母亲咨询前后的差异有统计学意义(P0.05)。《中国医学杂志》2022年7月第11期[p]: 102-107
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引用次数: 0
Hodgkin’s Lymphoma: A Rare Ophthalmic Case Report 霍奇金淋巴瘤:一罕见眼科病例报告
Pub Date : 2022-08-17 DOI: 10.3329/cbmj.v11i2.61287
S. Kadir, Tanjilla Hossain, Md. Golam Haider
Hodgkin’s lymphoma (HL) is a disease originating from lymphoid tissues; however, it may pose a diagnostic challenge. Ocular involvement is more prevalent in non-HL compared to HL. We have reported a rare case of Hodgkin’s lymphoma presented with forwarding bulging of left eye with pain, redness, and watering. The patient also complained of painless swelling of the submandibular lymph node when admitted into the National Institute of Ophthalmology and Hospital (NIOH), Dhaka, Bangladesh; later, incision and biopsy was done at ENT & Head-Neck Cancer Hospital, Dhaka, Bangladesh. Histopathology report revealed Hodgkin’s lymphoma. Hodgkin's lymphoma is a malignancy with unknown aetiology. With timely diagnosis and early treatment, our patient began to show gradual improvement with her symptoms. Prompt oncologic treatment and immunotherapy can be beneficial, if instituted early in the course of the disease. CBMJ 2022 July: vol. 11 no. 02 P: 158-161
霍奇金淋巴瘤(HL)是一种起源于淋巴组织的疾病;然而,它可能带来诊断上的挑战。与HL相比,非HL的眼部受累更为普遍。我们报告了一例罕见的霍奇金淋巴瘤,表现为左眼前移性肿胀,伴有疼痛、红肿和流泪。患者在孟加拉国达卡国立眼科研究所和医院(NIOH)住院时,还抱怨下颌下淋巴结无痛性肿胀;随后在孟加拉国达卡的耳鼻喉科和头颈肿瘤医院行切口和活检。组织病理学报告显示何杰金氏淋巴瘤。霍奇金淋巴瘤是一种病因不明的恶性肿瘤。通过及时诊断和早期治疗,患者的症状逐渐好转。及时的肿瘤治疗和免疫治疗是有益的,如果在疾病的早期进行。《中国医学杂志》2022年7月第11期[p]: 158-161
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引用次数: 0
期刊
Community Based Medical Journal
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