Pub Date : 2022-06-16DOI: 10.3329/cbmj.v11i1.60264
Sayla Chowdhury, A. Islam, M. Sultana, Mir Iftekhar Mostafiz
A prospective study was done in the Department of Paediatric Hematology & Oncology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, between January and June of 2012, to observe the renal and liver function status in children suffering from acute lymphoblastic leukemia (ALL) before and after induction of chemotherapy. A total of 30 diagnosed patients of acute lymphoblastic leukemia were enrolled in the study. Renal and liver function tests were done before and after induction of chemotherapy. All the patients of the study were within 2-11 years range. Mean age was 5.12±2.53 years. Maximum 43.3% patients were within 3-6 years of age followed by 33.3% up to 3 years of age,13.3% within 6-9 year of age range and 10% above 9-year age range. 73.3% were male and 26.7% were female. Among the liver functions tests, mean bilirubin level of the patients before induction of chemotherapy was 2.31±4.71 mg/dl and after induction of chemotherapy was 1.12±2.15 mg/dl (P=0.122). Mean SGPT levels were 35.33±15.82 IU/L and 75±57.12 IU/l respectively (P=0.001). Mean total protein levels were 67.05±6.99 gm/dl and 64.47±7.51 gm/dl respectively (P=0.06). All the patients were HBsAg negative. Among the renal function tests, mean blood urea level of the respondents before induction was 28.89±7.95 mg/dl and after induction was 30.67±9.39 mg/dl (P=0.429). Mean serum uric acid levels were 4.63±1.18 mg/dl and 5.12±0.44 mg/dl respectively (P=0.044). Mean serum creatinine levels were 0.74±0.27 mg/dl and 0.67±0.22 mg/dl respectively (P=0.168). Mean GFR was 99.77±37.38 ml/1.732/min. before induction of chemotherapy and 108.57±37.29 ml/1.732/min. following chemotherapy (P=0.177). Kidney and liver functions may be affected in ALL in children. Recognition of hepatic and renal impairment at the onset of illness helps judicious chemotherapy in management of ALL. CBMJ 2022 January: vol. 11 no. 01 P: 21-26
{"title":"Assessment of Renal and Liver Function Tests Before and After Induction of Chemotherapy in Newly Diagnosed Acute Lymphoblastic Leukemia in Children","authors":"Sayla Chowdhury, A. Islam, M. Sultana, Mir Iftekhar Mostafiz","doi":"10.3329/cbmj.v11i1.60264","DOIUrl":"https://doi.org/10.3329/cbmj.v11i1.60264","url":null,"abstract":"A prospective study was done in the Department of Paediatric Hematology & Oncology of Bangabandhu Sheikh Mujib Medical University (BSMMU), Dhaka, Bangladesh, between January and June of 2012, to observe the renal and liver function status in children suffering from acute lymphoblastic leukemia (ALL) before and after induction of chemotherapy. A total of 30 diagnosed patients of acute lymphoblastic leukemia were enrolled in the study. Renal and liver function tests were done before and after induction of chemotherapy. All the patients of the study were within 2-11 years range. Mean age was 5.12±2.53 years. Maximum 43.3% patients were within 3-6 years of age followed by 33.3% up to 3 years of age,13.3% within 6-9 year of age range and 10% above 9-year age range. 73.3% were male and 26.7% were female. Among the liver functions tests, mean bilirubin level of the patients before induction of chemotherapy was 2.31±4.71 mg/dl and after induction of chemotherapy was 1.12±2.15 mg/dl (P=0.122). Mean SGPT levels were 35.33±15.82 IU/L and 75±57.12 IU/l respectively (P=0.001). Mean total protein levels were 67.05±6.99 gm/dl and 64.47±7.51 gm/dl respectively (P=0.06). All the patients were HBsAg negative. Among the renal function tests, mean blood urea level of the respondents before induction was 28.89±7.95 mg/dl and after induction was 30.67±9.39 mg/dl (P=0.429). Mean serum uric acid levels were 4.63±1.18 mg/dl and 5.12±0.44 mg/dl respectively (P=0.044). Mean serum creatinine levels were 0.74±0.27 mg/dl and 0.67±0.22 mg/dl respectively (P=0.168). Mean GFR was 99.77±37.38 ml/1.732/min. before induction of chemotherapy and 108.57±37.29 ml/1.732/min. following chemotherapy (P=0.177). Kidney and liver functions may be affected in ALL in children. Recognition of hepatic and renal impairment at the onset of illness helps judicious chemotherapy in management of ALL. \u0000CBMJ 2022 January: vol. 11 no. 01 P: 21-26","PeriodicalId":10576,"journal":{"name":"Community Based Medical Journal","volume":"46 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79501673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-20DOI: 10.3329/cbmj.v10i2.59179
M. Mozaffor, A. S. M. Nurunnabi, M. Khasru, Md Joynul Islam
Chronic neuropathic pain disorders represent a common long-term disability globally. Its treatment has limited success because of its poorly understood mechanisms. Moreover, the effectiveness of neuropathic pain management regimens and procedures have been difficult to determine to date, due to the subjectivity related to pain perception, and a lack of standardized assessment of neuropathic pain. However, one of the most effective and popular management strategies of chronic neuropathic pain in recent times is spinal cord stimulation (SCS), a form of neuromodulation. This review aims to understand which substances inside the human body increase and decrease with increasing neuropathic pain. Through identifying those biomarkers and finding correlations between neuropathic pain and those components, we would like to apply our knowledge to develop a biomarker profile which will ultimately help to see prognosis or predict success of spinal cord stimulation therapy in patients suffering from chronic neuropathic pain. CBMJ 2021 January: vol. 10 no. 02 P: 118-122
{"title":"Biomarkers for Chronic Neuropathic Pain and Their Potential Application in Spinal Cord Stimulation (SCS) Therapy","authors":"M. Mozaffor, A. S. M. Nurunnabi, M. Khasru, Md Joynul Islam","doi":"10.3329/cbmj.v10i2.59179","DOIUrl":"https://doi.org/10.3329/cbmj.v10i2.59179","url":null,"abstract":"Chronic neuropathic pain disorders represent a common long-term disability globally. Its treatment has limited success because of its poorly understood mechanisms. Moreover, the effectiveness of neuropathic pain management regimens and procedures have been difficult to determine to date, due to the subjectivity related to pain perception, and a lack of standardized assessment of neuropathic pain. However, one of the most effective and popular management strategies of chronic neuropathic pain in recent times is spinal cord stimulation (SCS), a form of neuromodulation. This review aims to understand which substances inside the human body increase and decrease with increasing neuropathic pain. Through identifying those biomarkers and finding correlations between neuropathic pain and those components, we would like to apply our knowledge to develop a biomarker profile which will ultimately help to see prognosis or predict success of spinal cord stimulation therapy in patients suffering from chronic neuropathic pain. \u0000CBMJ 2021 January: vol. 10 no. 02 P: 118-122","PeriodicalId":10576,"journal":{"name":"Community Based Medical Journal","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75200040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-20DOI: 10.3329/cbmj.v10i2.59176
A. S. M. Nurunnabi, M. T. Sultan, Md Mozaharul Islam, Muhammad Abdul Kayum Shaikh
In November 2020, the Criminal Investigation Department of Bangladesh Police revealed in front of the media that a 20-year old young male allegedly had intercourse with female cadavers under postmortem examination inside the mortuary while working as an assistant to the official mortuary attendant in a medical college in Dhaka, Bangladesh. The subject of sex is still a taboo in the country, and an offence as bizarre as necrophilia is even beyond the imaginative capacity of majority of the population. However, this case of necrophilia has stirred the sentiment of the people and at the same time thrown challenges to the legislation and forensic psychiatry service of the country that we would like to focus on. There exists no penal provision in the country which criminalizes such “particular act of necrophilia”. However, we are interested to observe the consequences. Besides, no information was made available on psychiatric evaluation of the offender while arresting and sending him to the jail. We recommend strengthening of forensic psychiatry as a discipline to operate psychiatric evaluation in such cases which is crucial for legal proceedings. Moreover, making amendments to the existing laws should be considered to encompass this type of offence. CBMJ 2021 January: vol. 10 no. 02 P: 111-114
{"title":"Police Revealed a Case of Necrophilia in Dhaka, Bangladesh – Legal and Psychiatric Issues","authors":"A. S. M. Nurunnabi, M. T. Sultan, Md Mozaharul Islam, Muhammad Abdul Kayum Shaikh","doi":"10.3329/cbmj.v10i2.59176","DOIUrl":"https://doi.org/10.3329/cbmj.v10i2.59176","url":null,"abstract":"In November 2020, the Criminal Investigation Department of Bangladesh Police revealed in front of the media that a 20-year old young male allegedly had intercourse with female cadavers under postmortem examination inside the mortuary while working as an assistant to the official mortuary attendant in a medical college in Dhaka, Bangladesh. The subject of sex is still a taboo in the country, and an offence as bizarre as necrophilia is even beyond the imaginative capacity of majority of the population. However, this case of necrophilia has stirred the sentiment of the people and at the same time thrown challenges to the legislation and forensic psychiatry service of the country that we would like to focus on. There exists no penal provision in the country which criminalizes such “particular act of necrophilia”. However, we are interested to observe the consequences. Besides, no information was made available on psychiatric evaluation of the offender while arresting and sending him to the jail. We recommend strengthening of forensic psychiatry as a discipline to operate psychiatric evaluation in such cases which is crucial for legal proceedings. Moreover, making amendments to the existing laws should be considered to encompass this type of offence. \u0000CBMJ 2021 January: vol. 10 no. 02 P: 111-114","PeriodicalId":10576,"journal":{"name":"Community Based Medical Journal","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82610943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-20DOI: 10.3329/cbmj.v10i2.59149
Sadia Nusrat Alamgir, Kawsar Nigar, K. Nahar
A cross-sectional study was conducted in the Department of Obstetrics and Gynaecology, Mymensingh Medical College Hospital (MMCH), Bangladesh, between April and September of 2010, to observe and evaluate common complications in early puerperium. A total of 384 patients were selected for the study, who were admitted with immediate postpartum complications, or who experienced complications after delivery at MMCH. Most of the patients 202(52.6%) belongs to 21-30 years age group followed by 118(30.73%) in >30 years and 64(16.67%) in ≤20 years group. Low parity accounts for most patients, 217(56.5%), while grand multiparity was documented in 42(10.9%) patients. 211(54.95%) patients had no history of antenatal checkup. 179(46.62%) patients had home delivery, while the rest had institutional delivery. 239(62.24%) patients had normal vaginal delivery, while 129(33.6%) had Caesarean operation, 7(1.82%) needed vacuum extraction and 2.34% had forceps’ delivery. 146(38.02%) had their delivery without attending doctor, nurse/midwife or skilled birth attendant. Most of the patients, 281(73.18%), had their symptoms and signs within 24 hours of delivery, while 41(10.67%) and 62(16.15%) had within 48 hours and within 7 days respectively. Primary postpartum haemorrhage (PPH) was the leading complication found in 114(29.68%) patients, while the other major complications were puerperal sepsis 53(13.8%), urinary tract infection 40(10.42%), postpartum eclampsia 38(9.9%). 329(85.68%) patients were discharged without any morbidity; however, maternal mortality was observed in 18(4.68%) cases. Puerperal sepsis 5(28%), postpartum eclampsia 4(22%) and pulmonary embolism 3(17%) were the leading causes of mortality. Skilled obstetric care, active management of third stage of labour, prevention and treatment of anaemia, and maintenance of strict asepsis during delivery can prevent a considerable incidence of those complications. CBMJ 2021 January: vol. 10 no. 02 P: 85-90
{"title":"Early Postpartum Complications and Maternal Mortality: An Experience of Mymensingh Medical College Hospital, Bangladesh","authors":"Sadia Nusrat Alamgir, Kawsar Nigar, K. Nahar","doi":"10.3329/cbmj.v10i2.59149","DOIUrl":"https://doi.org/10.3329/cbmj.v10i2.59149","url":null,"abstract":"A cross-sectional study was conducted in the Department of Obstetrics and Gynaecology, Mymensingh Medical College Hospital (MMCH), Bangladesh, between April and September of 2010, to observe and evaluate common complications in early puerperium. A total of 384 patients were selected for the study, who were admitted with immediate postpartum complications, or who experienced complications after delivery at MMCH. Most of the patients 202(52.6%) belongs to 21-30 years age group followed by 118(30.73%) in >30 years and 64(16.67%) in ≤20 years group. Low parity accounts for most patients, 217(56.5%), while grand multiparity was documented in 42(10.9%) patients. 211(54.95%) patients had no history of antenatal checkup. 179(46.62%) patients had home delivery, while the rest had institutional delivery. 239(62.24%) patients had normal vaginal delivery, while 129(33.6%) had Caesarean operation, 7(1.82%) needed vacuum extraction and 2.34% had forceps’ delivery. 146(38.02%) had their delivery without attending doctor, nurse/midwife or skilled birth attendant. Most of the patients, 281(73.18%), had their symptoms and signs within 24 hours of delivery, while 41(10.67%) and 62(16.15%) had within 48 hours and within 7 days respectively. Primary postpartum haemorrhage (PPH) was the leading complication found in 114(29.68%) patients, while the other major complications were puerperal sepsis 53(13.8%), urinary tract infection 40(10.42%), postpartum eclampsia 38(9.9%). 329(85.68%) patients were discharged without any morbidity; however, maternal mortality was observed in 18(4.68%) cases. Puerperal sepsis 5(28%), postpartum eclampsia 4(22%) and pulmonary embolism 3(17%) were the leading causes of mortality. Skilled obstetric care, active management of third stage of labour, prevention and treatment of anaemia, and maintenance of strict asepsis during delivery can prevent a considerable incidence of those complications. \u0000CBMJ 2021 January: vol. 10 no. 02 P: 85-90","PeriodicalId":10576,"journal":{"name":"Community Based Medical Journal","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87124839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-20DOI: 10.3329/cbmj.v10i2.59146
Mohammad Ariful Islam, Afroza E Alam, S. S. B. Bari Rasel, M. Rana, Amir Abdulla Hel Azam, Md Shahjahan Siraj, Syeed Mehbub Ul Kadir
A cross-sectional, prospective study was conducted in a tertiary level eye hospital in the southern region of Bangladesh, between January and December of 2019, to assess the magnitude of blindness with varying disorders of the eye. All the reported patients irrespective of age and gender were included in this study. Patients were divided into three age groups: 0-25 years, 26-50 years and above 50 years. Demographic variables and eye diseases diagnosed were recorded and analyzed. More than 1.5 lac patients attended the hospital during the study period. Male patients were preponderance 79058 (52.05%) than female 72814 (47.95%). The most common group was above 50 years 75055 (49.42%). Patients related with blindness were 42189 (27.78%). Cataract were the most common disorder of reversible blindness 38662 (91.64%) followed by corneal disorders both reversible and irreversible blindness 1931 (4.57%), and other disorders 1596 (3.78%) with irreversible blindness included ocular trauma, posterior segment disease and glaucoma. Age related cataract (ARC) was 37394 (96.72%) among the patients with cataract, and ARC was found 35272 (83.6%) among the patients related to blindness above 50 years of age. More than 90 percent of the patients 38662 (91.64%) were attended for reversible blindness with cataract. To summarize, age related cataract was the most common cause of reversible blindness among the patients >50 years of age. The causes of irreversible blindness included ocular trauma, corneal ulcer, diabetic retinopathy and glaucoma. CBMJ 2021 January: vol. 10 no. 02 P: 70-74
{"title":"Blindness Scenario in the Southern Region of Bangladesh","authors":"Mohammad Ariful Islam, Afroza E Alam, S. S. B. Bari Rasel, M. Rana, Amir Abdulla Hel Azam, Md Shahjahan Siraj, Syeed Mehbub Ul Kadir","doi":"10.3329/cbmj.v10i2.59146","DOIUrl":"https://doi.org/10.3329/cbmj.v10i2.59146","url":null,"abstract":"A cross-sectional, prospective study was conducted in a tertiary level eye hospital in the southern region of Bangladesh, between January and December of 2019, to assess the magnitude of blindness with varying disorders of the eye. All the reported patients irrespective of age and gender were included in this study. Patients were divided into three age groups: 0-25 years, 26-50 years and above 50 years. Demographic variables and eye diseases diagnosed were recorded and analyzed. More than 1.5 lac patients attended the hospital during the study period. Male patients were preponderance 79058 (52.05%) than female 72814 (47.95%). The most common group was above 50 years 75055 (49.42%). Patients related with blindness were 42189 (27.78%). Cataract were the most common disorder of reversible blindness 38662 (91.64%) followed by corneal disorders both reversible and irreversible blindness 1931 (4.57%), and other disorders 1596 (3.78%) with irreversible blindness included ocular trauma, posterior segment disease and glaucoma. Age related cataract (ARC) was 37394 (96.72%) among the patients with cataract, and ARC was found 35272 (83.6%) among the patients related to blindness above 50 years of age. More than 90 percent of the patients 38662 (91.64%) were attended for reversible blindness with cataract. To summarize, age related cataract was the most common cause of reversible blindness among the patients >50 years of age. The causes of irreversible blindness included ocular trauma, corneal ulcer, diabetic retinopathy and glaucoma. CBMJ 2021 January: vol. 10 no. 02 P: 70-74","PeriodicalId":10576,"journal":{"name":"Community Based Medical Journal","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79227169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-20DOI: 10.3329/cbmj.v10i2.59173
M. Islam, Md Tufael Hossain, M. Uddin, M. R. Chowdhury, M. Hasan
Objective: To determine the effect of interlocking intramedullary nail in treatment of tibia and fibula fractures and analyze its efficacy by clinical and radiological parameters. Methods: From August 2015 to September 2017, in Community Based Medical College Hospital, Orthopedics department, 15 patients with tibia and fibula fractures were managed by open reduction and interlocking nail and each case was followed up for 7 months. The cases were assessed clinically and by radiology. Results: There were 13 males and 2 females involving 10 right legs and 5 left legs. Ages of patients ranged from 17 years to 60 years with mean age 36.13 years and standard deviation 11.813 years. The location of fractures was 1 upper, 2 middle and 12 lower. There was association of 1 fracture femur right side. Conclusion: Use of interlocking intramedullary nail in management of tibia and fibula fractures was good in majority of cases. CBMJ 2021 January: vol. 10 no. 02 P: 91-97
{"title":"Experience in the management of distal third tibia and fibula fractures by interlocking intramedullary nail in Community Based Medical College Hospital","authors":"M. Islam, Md Tufael Hossain, M. Uddin, M. R. Chowdhury, M. Hasan","doi":"10.3329/cbmj.v10i2.59173","DOIUrl":"https://doi.org/10.3329/cbmj.v10i2.59173","url":null,"abstract":"Objective: To determine the effect of interlocking intramedullary nail in treatment of tibia and fibula fractures and analyze its efficacy by clinical and radiological parameters. \u0000Methods: From August 2015 to September 2017, in Community Based Medical College Hospital, Orthopedics department, 15 patients with tibia and fibula fractures were managed by open reduction and interlocking nail and each case was followed up for 7 months. The cases were assessed clinically and by radiology. \u0000Results: There were 13 males and 2 females involving 10 right legs and 5 left legs. Ages of patients ranged from 17 years to 60 years with mean age 36.13 years and standard deviation 11.813 years. The location of fractures was 1 upper, 2 middle and 12 lower. There was association of 1 fracture femur right side. \u0000Conclusion: Use of interlocking intramedullary nail in management of tibia and fibula fractures was good in majority of cases. \u0000CBMJ 2021 January: vol. 10 no. 02 P: 91-97","PeriodicalId":10576,"journal":{"name":"Community Based Medical Journal","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80073317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-20DOI: 10.3329/cbmj.v10i2.59175
F. Sultana, A. Sattar, Sutapa Chatterjee, Rokshana Ahmed, Zereen Sultana Deepa, Luna Ahmed, M. Uddin
A cross-sectional study was conducted in the Department of Radiology & Imaging, in collaboration with the Department of Obstetrics & Gynaecology, in Dhaka Medical College Hospital and Bangabandhu Sheikh Mujib Medical University Hospital, Dhaka, Bangladesh, between July 2010 and March 2012, to evaluate the diagnostic usefulness of transvaginal color doppler ultrasonography (TVCDU) in differentiating benign and malignant uterine tumours. A total of fifty women, diagnosed as having uterine tumours both clinically and using ultrasound, participated in the study. They were evaluated preoperatively using TVCDU. All the study participants underwent surgical operation and resected specimens were sent for histopathological examination. Histopathology reports were correlated with the of colour Doppler findings. The mean age of the patients was 47.72±8.79 years. Major complaints were menorrhagia (58%), dysmenorrhoea (50%) and lump in the lower abdomen (48%). Neovascularization was found in 16(32%) cases. The mean resistance index and pulsatility index were much lower in malignant tumours than that of the benign counterpart (0.35±0.03 vs. 0.67±0.01 and 0.65±0.14 vs. 1.35±0.11 respectively); the difference was statistically significant (P<0.001). The sensitivity, specificity, positive and negative predictive values of TVCDU were found 86.7%, 97.14%, 92.85% and 94.4% respectively. Overall diagnostic accuracy was 94%. To summarize, blood flow characteristics of benign and malignant uterine tumours, as evident on color Doppler imaging, have distinct diagnostic value. Hence, transvaginal colour Doppler ultrasound examination can be used as an easily available, efficient, and non-invasive diagnostic modality in differentiation of uterine tumours, which can be histologically confirmed later. CBMJ 2021 January: vol. 10 no. 02 P: 105-110
{"title":"Transvaginal Colour Doppler Ultrasound Study of Uterine Tumours with Histopathological Correlation","authors":"F. Sultana, A. Sattar, Sutapa Chatterjee, Rokshana Ahmed, Zereen Sultana Deepa, Luna Ahmed, M. Uddin","doi":"10.3329/cbmj.v10i2.59175","DOIUrl":"https://doi.org/10.3329/cbmj.v10i2.59175","url":null,"abstract":"A cross-sectional study was conducted in the Department of Radiology & Imaging, in collaboration with the Department of Obstetrics & Gynaecology, in Dhaka Medical College Hospital and Bangabandhu Sheikh Mujib Medical University Hospital, Dhaka, Bangladesh, between July 2010 and March 2012, to evaluate the diagnostic usefulness of transvaginal color doppler ultrasonography (TVCDU) in differentiating benign and malignant uterine tumours. A total of fifty women, diagnosed as having uterine tumours both clinically and using ultrasound, participated in the study. They were evaluated preoperatively using TVCDU. All the study participants underwent surgical operation and resected specimens were sent for histopathological examination. Histopathology reports were correlated with the of colour Doppler findings. The mean age of the patients was 47.72±8.79 years. Major complaints were menorrhagia (58%), dysmenorrhoea (50%) and lump in the lower abdomen (48%). Neovascularization was found in 16(32%) cases. The mean resistance index and pulsatility index were much lower in malignant tumours than that of the benign counterpart (0.35±0.03 vs. 0.67±0.01 and 0.65±0.14 vs. 1.35±0.11 respectively); the difference was statistically significant (P<0.001). The sensitivity, specificity, positive and negative predictive values of TVCDU were found 86.7%, 97.14%, 92.85% and 94.4% respectively. Overall diagnostic accuracy was 94%. To summarize, blood flow characteristics of benign and malignant uterine tumours, as evident on color Doppler imaging, have distinct diagnostic value. Hence, transvaginal colour Doppler ultrasound examination can be used as an easily available, efficient, and non-invasive diagnostic modality in differentiation of uterine tumours, which can be histologically confirmed later. \u0000CBMJ 2021 January: vol. 10 no. 02 P: 105-110","PeriodicalId":10576,"journal":{"name":"Community Based Medical Journal","volume":"322 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76289459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-20DOI: 10.3329/cbmj.v10i2.59148
M. Bodiuzzaman
Background: Non-communicable diseases (NCDs) are increasing trend globally and account for the majority of all new cases of morbidity and mortality. Previously, its prevalence was more in developed countries, but now it is increasing in low income settings. Early diagnosis, treatment and preventive measures will reduce the mortality, morbidity, and financial burden on families and community. Objectives: The study was carried out in a tertiary care hospital to explore the incidence of common NCDs and whether there was differentiation in ages, sexes and residences among hospitalized patients. Methods: A descriptive cross sectional type of observational study was done in a tertiary care hospital, Bangabandhu Sheikh Mujib Medical College Hospital (former Faridpur Medical College Hospital), Faridpur, Bangladesh from January 2019 to July 2019 for a period of 7 months. Patients were selected randomly in different adult medicine wards, including all sexes, races, and residences. Common NCDs included were cardiovascular diseases like hypertension (HTN), ischemic heart disease (IHD) and stroke; chronic respiratory diseases like COPD and asthma; diabetes mellitus (DM) and malignancy. Result: A total of 1119 patients were hospitalized for different reasons; among them, 891 patients were diagnosed as NCDs (79.62%). In this study, male patients were more than females (63.41% vs. 36.59%), common age groups between 46 and 60 (33%) and the next age groups between 31 and 45 (26.26%); the mean age was 41.51. Younger people aged 60 years are affected more than the elderly. Rural patients were more than urban (64.54% vs. 35.46%). Common NCDs were stroke (25.58%), hypertension (18.40%), diabetes (12.0%), ischemic heart disease (9.20%), chronic respiratory diseases (6.95%), malignancy (3.36%) and other less common non-communicable diseases (24.47%). Conclusion: Globally, the world is facing a growing burden of NCDs and it is a great challenge to face this upcoming situation. Measure should be taken, that how can we reduce the incidences, morbidity and mortality of those devastating diseases by prevention of their risk factors and early treatment. CBMJ 2021 January: vol. 10 no. 02 P: 80-84
背景:非传染性疾病在全球呈上升趋势，占所有新发病和死亡病例的大多数。以前，它在发达国家更为普遍，但现在它在低收入环境中正在增加。早期诊断、治疗和预防措施将降低死亡率、发病率，减轻家庭和社区的经济负担。目的:本研究在某三级医院开展，探讨常见非传染性疾病的发病率以及住院患者中是否存在年龄、性别和居住地的差异。方法:于2019年1月至2019年7月在孟加拉国法里德普尔邦班班杜谢赫穆吉布医学院医院(前法里德普尔医学院医院)三级保健医院进行描述性横断面型观察性研究，为期7个月。患者随机选择在不同的成人医学病房，包括所有性别、种族和居住地。常见的非传染性疾病包括心血管疾病，如高血压(HTN)、缺血性心脏病(IHD)和中风;慢性呼吸系统疾病，如慢性阻塞性肺病和哮喘;糖尿病(DM)和恶性肿瘤。结果:共有1119例患者因不同原因住院;其中诊断为非传染性疾病891例(79.62%)。本组患者中男性多于女性(63.41% vs. 36.59%)，常见年龄组为46 ~ 60岁(33%)，次年龄组为31 ~ 45岁(26.26%);平均年龄41.51岁。60岁的年轻人比老年人更容易受到影响。农村患者多于城市患者(64.54% vs. 35.46%)。常见的非传染性疾病为中风(25.58%)、高血压(18.40%)、糖尿病(12.0%)、缺血性心脏病(9.20%)、慢性呼吸系统疾病(6.95%)、恶性肿瘤(3.36%)和其他较少见的非传染性疾病(24.47%)。结论:在全球范围内，世界正面临着日益沉重的非传染性疾病负担，面对这一即将到来的形势是一项巨大的挑战。我们应该采取措施，如何通过预防危险因素和早期治疗来降低这些毁灭性疾病的发病率、发病率和死亡率。中华医学杂志2021年1月第10卷第10期[02:80 . 84
{"title":"Prevalence of Major Non- Communicable Diseases in a Tertiary Care Hospital","authors":"M. Bodiuzzaman","doi":"10.3329/cbmj.v10i2.59148","DOIUrl":"https://doi.org/10.3329/cbmj.v10i2.59148","url":null,"abstract":"Background: Non-communicable diseases (NCDs) are increasing trend globally and account for the majority of all new cases of morbidity and mortality. Previously, its prevalence was more in developed countries, but now it is increasing in low income settings. Early diagnosis, treatment and preventive measures will reduce the mortality, morbidity, and financial burden on families and community. \u0000Objectives: The study was carried out in a tertiary care hospital to explore the incidence of common NCDs and whether there was differentiation in ages, sexes and residences among hospitalized patients. \u0000Methods: A descriptive cross sectional type of observational study was done in a tertiary care hospital, Bangabandhu Sheikh Mujib Medical College Hospital (former Faridpur Medical College Hospital), Faridpur, Bangladesh from January 2019 to July 2019 for a period of 7 months. Patients were selected randomly in different adult medicine wards, including all sexes, races, and residences. Common NCDs included were cardiovascular diseases like hypertension (HTN), ischemic heart disease (IHD) and stroke; chronic respiratory diseases like COPD and asthma; diabetes mellitus (DM) and malignancy. \u0000Result: A total of 1119 patients were hospitalized for different reasons; among them, 891 patients were diagnosed as NCDs (79.62%). In this study, male patients were more than females (63.41% vs. 36.59%), common age groups between 46 and 60 (33%) and the next age groups between 31 and 45 (26.26%); the mean age was 41.51. Younger people aged 60 years are affected more than the elderly. Rural patients were more than urban (64.54% vs. 35.46%). Common NCDs were stroke (25.58%), hypertension (18.40%), diabetes (12.0%), ischemic heart disease (9.20%), chronic respiratory diseases (6.95%), malignancy (3.36%) and other less common non-communicable diseases (24.47%). \u0000Conclusion: Globally, the world is facing a growing burden of NCDs and it is a great challenge to face this upcoming situation. Measure should be taken, that how can we reduce the incidences, morbidity and mortality of those devastating diseases by prevention of their risk factors and early treatment. \u0000CBMJ 2021 January: vol. 10 no. 02 P: 80-84","PeriodicalId":10576,"journal":{"name":"Community Based Medical Journal","volume":"6 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73237330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-20DOI: 10.3329/cbmj.v10i2.59147
Bilqis Akter
Introduction: Some studies have shown the possible involvement of Helicobacter pylori (H. pylori) infection in chronic idiopathic urticaria, but the relationship remains controversial. The aim of this study was to quantitatively assess the association between H. pylori infection and chronic idiopathic urticaria. Material & Methods: A case-control type of analytical study was conducted in the department of Dermatology and Venereology, Naval Base Hospital (BNS Patenga), Chattogram, Bangladesh for duration of 06 months. Total 50 patients were enrolled in this study. 25 Patients of CIU with no identifiable cause were taken as case and patients without urticaria were taken as control, attending in the outpatient department. H. pylori infection was confirmed by Serum IgG for H. pylori test. Results: The result shows that Helicobacter pylori significantly affect a high percentage of patients with chronic idiopathic urticaria and response to eradication therapy was evident in more patients in whom H. pylori were eradicated. Conclusion: The study shows that Helicobacter pylori significantly affects a high percentage of patients with CIU. Response to eradication therapy was evident in more patients in whom H. pylori was eradicated while few patients showed no response despite eradication of H. pylori. The result of this study suggests that H. pylori infection should be included in diagnostic work up of patients with no response to usual treatment for CIU. CBMJ 2021 January: vol. 10 no. 02 P: 75-79
{"title":"Association between Chronic Idiopathic Urticaria (CIU) and H. Pylori Infection: A Single Center Case-Control Study in Bangladesh","authors":"Bilqis Akter","doi":"10.3329/cbmj.v10i2.59147","DOIUrl":"https://doi.org/10.3329/cbmj.v10i2.59147","url":null,"abstract":"Introduction: Some studies have shown the possible involvement of Helicobacter pylori (H. pylori) infection in chronic idiopathic urticaria, but the relationship remains controversial. The aim of this study was to quantitatively assess the association between H. pylori infection and chronic idiopathic urticaria. \u0000Material & Methods: A case-control type of analytical study was conducted in the department of Dermatology and Venereology, Naval Base Hospital (BNS Patenga), Chattogram, Bangladesh for duration of 06 months. Total 50 patients were enrolled in this study. 25 Patients of CIU with no identifiable cause were taken as case and patients without urticaria were taken as control, attending in the outpatient department. H. pylori infection was confirmed by Serum IgG for H. pylori test. \u0000Results: The result shows that Helicobacter pylori significantly affect a high percentage of patients with chronic idiopathic urticaria and response to eradication therapy was evident in more patients in whom H. pylori were eradicated. \u0000Conclusion: The study shows that Helicobacter pylori significantly affects a high percentage of patients with CIU. Response to eradication therapy was evident in more patients in whom H. pylori was eradicated while few patients showed no response despite eradication of H. pylori. The result of this study suggests that H. pylori infection should be included in diagnostic work up of patients with no response to usual treatment for CIU. \u0000CBMJ 2021 January: vol. 10 no. 02 P: 75-79","PeriodicalId":10576,"journal":{"name":"Community Based Medical Journal","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83886459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-03-20DOI: 10.3329/cbmj.v10i2.59178
B. K. Biswas, Md Manzur Ul Karim Khan, Md. Shahidul Islam, N. Islam
Skin cancers contribute very less to the total number of carcinomas. Particularly when on the face or exposed parts affect cosmetically more than functionally. Basal Cell Carcinoma over face is a locally destructive malignancy of the skin which rarely metastasizes. Basal cell carcinomas are the most common type of cancer in Europe, Australia, and the USA. A case of basal cell carcinoma is reported here in an adult female living in a rural area, who came for cosmetic purpose in the Department of Dermatology & Venereology, Community Based Medical College, Bangladesh (CBMC,B) Hospital, Mymensingh, Bangladesh and was transferred to the Department of Otolaryngology & Neck-Head Surgery of the same institution for better management. She was treated with best of the modalities available, i.e., wide local excision with local Nasolabial flap reconstruction with follow up. CBMJ 2021 January: vol. 10 no. 02 P: 115-117
{"title":"Basal Cell Carcinoma at the Tip of the Nose – A Case Report","authors":"B. K. Biswas, Md Manzur Ul Karim Khan, Md. Shahidul Islam, N. Islam","doi":"10.3329/cbmj.v10i2.59178","DOIUrl":"https://doi.org/10.3329/cbmj.v10i2.59178","url":null,"abstract":"Skin cancers contribute very less to the total number of carcinomas. Particularly when on the face or exposed parts affect cosmetically more than functionally. Basal Cell Carcinoma over face is a locally destructive malignancy of the skin which rarely metastasizes. Basal cell carcinomas are the most common type of cancer in Europe, Australia, and the USA. A case of basal cell carcinoma is reported here in an adult female living in a rural area, who came for cosmetic purpose in the Department of Dermatology & Venereology, Community Based Medical College, Bangladesh (CBMC,B) Hospital, Mymensingh, Bangladesh and was transferred to the Department of Otolaryngology & Neck-Head Surgery of the same institution for better management. She was treated with best of the modalities available, i.e., wide local excision with local Nasolabial flap reconstruction with follow up. \u0000CBMJ 2021 January: vol. 10 no. 02 P: 115-117","PeriodicalId":10576,"journal":{"name":"Community Based Medical Journal","volume":"30 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88757499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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