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Contemporary topics in immunobiology最新文献

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Separation of individual kinds of cells from tumors. 从肿瘤中分离不同种类的细胞。
Contemporary topics in immunobiology
Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_2
T G Pretlow, T P Pretlow
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引用次数: 17
Cancer: a problem in somatic cell evolution. 癌症:体细胞进化中的一个问题。
Contemporary topics in immunobiology
Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3701-0_1
J L Collins, P Q Patek, M Cohn
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引用次数: 6
An immunologic network. 免疫网络。
Contemporary topics in immunobiology
Pub Date : 1980-01-01 DOI: 10.1007/978-1-4615-9131-3_8
D A Rowley, H Köhler, J D Cowan

The immune system is a complex network of molecules and cells specifically connected by the complementarity of receptors for antigen and receptors for receptors. The network includes multiple positive- and negative-feedback loops, which modulate the type, magnitude, and duration of responses. The great challenge is to devise ways to manipulate the system specifically to induce effective autoimmunity to cancer, to prevent allograft rejection, and to turn off undesirable responses in allergies and autoimmune diseases. Recognition of the immune system as a network helps to explain why these objectives are so difficult and why manipulation of multiple components to achieve desired regulation may be required. But presumably manipulation must be focused on connectivity between receptor for epitope and receptor for receptor to achieve a high degree of specific regulation.

免疫系统是一个复杂的分子和细胞网络，通过抗原受体和受体受体的互补性特异性地连接在一起。该网络包括多个正反馈和负反馈回路，它们调节响应的类型、幅度和持续时间。最大的挑战是设计出特定的方法来操纵系统，以诱导对癌症的有效自身免疫，防止同种异体移植排斥，并关闭过敏和自身免疫性疾病中的不良反应。将免疫系统视为一个网络有助于解释为什么这些目标如此困难，以及为什么需要操纵多个组件来实现预期的调节。但据推测，操纵必须集中在受体对表位和受体对受体之间的连通性上，才能实现高度的特异性调控。
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引用次数: 24
Mononuclear cells and IgG associated with human malignant tissue. 与人类恶性组织相关的单核细胞和IgG。
Contemporary topics in immunobiology
Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_7
O Tønder, R Matre, F Wesenberg
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引用次数: 4
Evidence for membrane-bound antibodies directed against antigens expressed on tumors. 针对肿瘤抗原表达的膜结合抗体的证据。
Contemporary topics in immunobiology
Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_8
S von Kleist, M King, C Huet
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引用次数: 6
A review of data, problems, and open questions pertaining to in situ tumor immunity. 回顾有关原位肿瘤免疫的数据、问题和开放性问题。
Contemporary topics in immunobiology
Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_1
S W Russell, I P Witz, R B Herberman
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引用次数: 18
Tumor immunity in the peritoneal cavity. 腹膜腔肿瘤免疫。
Contemporary topics in immunobiology
Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_14
G Berke, B Schick
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引用次数: 3
Continuous cytotoxic T-cell lines. 连续的细胞毒性t细胞系。
Contemporary topics in immunobiology
Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3701-0_4
K A Smith
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引用次数: 11
Discrimination of self and non-self in plants. 植物对自我和非自我的辨别
Contemporary topics in immunobiology
Pub Date : 1980-01-01 DOI: 10.1007/978-1-4615-9131-3_1
R B Knox, A E Clarke
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引用次数: 20
Evidence for mononuclear phagocytes in solid neoplasms and appraisal of their nonspecific cytotoxic capabilities. 实体肿瘤中单核吞噬细胞存在的证据及其非特异性细胞毒能力的评价。
Contemporary topics in immunobiology
Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_6
S W Russell, G Y Gillespie, J L Pace
{"title":"Evidence for mononuclear phagocytes in solid neoplasms and appraisal of their nonspecific cytotoxic capabilities.","authors":"S W Russell,&nbsp;G Y Gillespie,&nbsp;J L Pace","doi":"10.1007/978-1-4684-3677-8_6","DOIUrl":"https://doi.org/10.1007/978-1-4684-3677-8_6","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18419333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 39
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