D. Lazić, D. Blagojević, Dragana Kešelj, Z. Petrović, Neboǰsa Vasiljević
Crni Guber natural mineral water belongs to a group of highly mineralized iron-arsenic waters, which can be used for therapeutic purposes. In order to determine a more precise and accurate method for determining iron content, a comparison of ICP-OES and spectrophotometric method was performed. For the purposes of analysis using the ICP-OES method water samples were prepared with identical and different dilutions compared to the samples for the analysis performed using the spectrophotometric method. The G-test was used to check for the existence of outlier values in the obtained results, while the precision and accuracy of the method were verified by using the F-test and t-test. The aforementioned tests showed that the spectrophotometric method was more precise and accurate when the samples were prepared with identical dilution. When analyzing samples with different dilutions, the spectrophotometric method proved to be more precise, while in terms of accuracy there was no statistically significant difference between the methods.
{"title":"DETERMINATION OF IRON CONTENT IN NATURAL MINERAL WATER: COMPARISON OF ICP-OES AND SPECTROPHOTOMETRIC METHOD","authors":"D. Lazić, D. Blagojević, Dragana Kešelj, Z. Petrović, Neboǰsa Vasiljević","doi":"10.7251/comen2301048l","DOIUrl":"https://doi.org/10.7251/comen2301048l","url":null,"abstract":"Crni Guber natural mineral water belongs to a group of highly mineralized iron-arsenic waters, which can be used for therapeutic purposes. In order to determine a more precise and accurate method for determining iron content, a comparison of ICP-OES and spectrophotometric method was performed. For the purposes of analysis using the ICP-OES method water samples were prepared with identical and different dilutions compared to the samples for the analysis performed using the spectrophotometric method. The G-test was used to check for the existence of outlier values in the obtained results, while the precision and accuracy of the method were verified by using the F-test and t-test. The aforementioned tests showed that the spectrophotometric method was more precise and accurate when the samples were prepared with identical dilution. When analyzing samples with different dilutions, the spectrophotometric method proved to be more precise, while in terms of accuracy there was no statistically significant difference between the methods.","PeriodicalId":10617,"journal":{"name":"Contemporary Materials","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79838725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Rajić, Srđan Vuković, A. Vuković, Vesna Gojković Cvjetković, S. Pelemiš
Recently, nanobiotechnology has a very wide range of applications, and one of them is the application of nanoparticles for delivery systems of active substances. Nanoparticles are one of the most unique entities that enhance performance, expand applications, and provide an opportunity to develop materials that can address many scientific challenges. Hollow nanoparticles-nanocapsules built from plant proteins have suitable physico-chemical and functional properties, which enable them to encapsulate hydrophilic and hydrophobic bioactive compounds. Apart from their essential function of providing amino acids for human consumption, proteins also play a prominent role in the preparation, processing, storage and consumption of food and contribute to the quality and sensory properties of food products. The development of nanoparticles with specific properties is encouraged by their application in nanotechnology, food and agricultural systems, especially the development of bioactive components of functional food, with improved solubility, physico-chemical stability, oral bioavailability and sensory characteristics. This paper provides an overview of plant proteins that can be used for the production of nanocapsules, their functional properties, as well as the methods that can be used to obtain nanocapsules based on plant proteins.
{"title":"NANOCAPSULES BASED ON PLANT PROTEINS","authors":"D. Rajić, Srđan Vuković, A. Vuković, Vesna Gojković Cvjetković, S. Pelemiš","doi":"10.7251/comen2202185r","DOIUrl":"https://doi.org/10.7251/comen2202185r","url":null,"abstract":"Recently, nanobiotechnology has a very wide range of applications, and one of them is the application of nanoparticles for delivery systems of active substances. Nanoparticles are one of the most unique entities that enhance performance, expand applications, and provide an opportunity to develop materials that can address many scientific challenges. Hollow nanoparticles-nanocapsules built from plant proteins have suitable physico-chemical and functional properties, which enable them to encapsulate hydrophilic and hydrophobic bioactive compounds. Apart from their essential function of providing amino acids for human consumption, proteins also play a prominent role in the preparation, processing, storage and consumption of food and contribute to the quality and sensory properties of food products. The development of nanoparticles with specific properties is encouraged by their application in nanotechnology, food and agricultural systems, especially the development of bioactive components of functional food, with improved solubility, physico-chemical stability, oral bioavailability and sensory characteristics. This paper provides an overview of plant proteins that can be used for the production of nanocapsules, their functional properties, as well as the methods that can be used to obtain nanocapsules based on plant proteins.","PeriodicalId":10617,"journal":{"name":"Contemporary Materials","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82510931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Stamenkovic, N. Nedeljkovic, V. Mirjanić, V. Stojic, N. Marinković, Ivan Arsic
In this case 7-year-old boy with severe distal bite caused by mandibular retrognathism was treated by Fränkel functional regulator type Ic. Aim: The aim of this paper was to show main skeletal and dental effects of Fränkel functional regulator type I in early treatment of skeletal distal bite. Appropriate timing for usage of functional appliance can successfully correct mandibular retrognathism and avoid later prolonged orthodontic treatment. Material and method: In this case boy in early mixed dentition with skeletal Class II was treated. Before treatment clinical examinations, study cast analysis, intraoral and extraoral photos, orthopantomogram and lateral cephalogram have been done. Active phase of treatment lasted 18 months. During this period patient wore an appliance continuously for 24 hours except during meals. An appliance was made on the basis of registered construction bite in position of posterior teeth in Class I. Patient activated screws in appliance once in 10 days. Lateral cephalogram, intraoral and extraoral photos have been done on the end of active phase of orthodontic treatment. Results and conclusion: Before treatment patient had severe Class II with deep bite and overjet of 11mm. Parameters on lateral cephalogram were: SNA 83°, SNB 77°, ANB 6°, Wits apprasial 9mm, SpP/MP 27°, FMA 21°, FMIA 59°, IMPA 100°, I/SpP 117°, Bjork 390°, Jarabak ratio 68%. After active phase of treatment patient had stable occlusion in Class I, reduced overbite and overjet of 3mm. At the end of the treatment measured parameters on the lateral cephalogram were: SNA 83°, SNB 79°, ANB 4°, Wits apprasial 0mm, SpP/MP 25°, FMA 20°, FMIA 59°, IMPA 101°, I/SpP 115°, Bjork 390°, Jarabak ratio 68%. Fränkel functional regulator is very successfull appliance for early treatment of skeletal distal bite, before pubertal growth spurt. This appliance causes skeletal and dentoalveolar changes and contributes to the correction of swallowing and speech.
{"title":"EARLY TREATMENT OF SKELETAL CLASS II BY FRÄNKEL FUNCTIONAL REGULATOR","authors":"Z. Stamenkovic, N. Nedeljkovic, V. Mirjanić, V. Stojic, N. Marinković, Ivan Arsic","doi":"10.7251/comen2202216s","DOIUrl":"https://doi.org/10.7251/comen2202216s","url":null,"abstract":"In this case 7-year-old boy with severe distal bite caused by mandibular retrognathism was treated by Fränkel functional regulator type Ic. Aim: The aim of this paper was to show main skeletal and dental effects of Fränkel functional regulator type I in early treatment of skeletal distal bite. Appropriate timing for usage of functional appliance can successfully correct mandibular retrognathism and avoid later prolonged orthodontic treatment. Material and method: In this case boy in early mixed dentition with skeletal Class II was treated. Before treatment clinical examinations, study cast analysis, intraoral and extraoral photos, orthopantomogram and lateral cephalogram have been done. Active phase of treatment lasted 18 months. During this period patient wore an appliance continuously for 24 hours except during meals. An appliance was made on the basis of registered construction bite in position of posterior teeth in Class I. Patient activated screws in appliance once in 10 days. Lateral cephalogram, intraoral and extraoral photos have been done on the end of active phase of orthodontic treatment. Results and conclusion: Before treatment patient had severe Class II with deep bite and overjet of 11mm. Parameters on lateral cephalogram were: SNA 83°, SNB 77°, ANB 6°, Wits apprasial 9mm, SpP/MP 27°, FMA 21°, FMIA 59°, IMPA 100°, I/SpP 117°, Bjork 390°, Jarabak ratio 68%. After active phase of treatment patient had stable occlusion in Class I, reduced overbite and overjet of 3mm. At the end of the treatment measured parameters on the lateral cephalogram were: SNA 83°, SNB 79°, ANB 4°, Wits apprasial 0mm, SpP/MP 25°, FMA 20°, FMIA 59°, IMPA 101°, I/SpP 115°, Bjork 390°, Jarabak ratio 68%. Fränkel functional regulator is very successfull appliance for early treatment of skeletal distal bite, before pubertal growth spurt. This appliance causes skeletal and dentoalveolar changes and contributes to the correction of swallowing and speech.","PeriodicalId":10617,"journal":{"name":"Contemporary Materials","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76361161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nikola Kotorcevic, Nina Busarac, S. Nježić, D. Džunić, N. Grujovic, F. Živić
Mechanical surface preparation is a common technique for removing contaminants from surface metal layers. Unlike chemical preparation, it does not require special safety measures, including those for disposal of by-products or toxic materials, thus making it more accessible for different industries. We investigated tribological testing as the experimental method to determine the quality of the coating and the influence of the initial mechanical surface treatment. Samples were made of aluminium alloy EN AW 5083 H111 that was shot blasted with white cast aluminium with resulting surface roughness of Rz=38.908 μm. Samples were further coated with Lankwitzer EvoCor 164 2-component epoxy primer. Tribological test realised on nanotribometer is described and output parameters have been analysed: friction coefficient and penetration depth. Ball-on-flat, dry contact tribological setup was used, with 100 mN normal load, under linear reciprocating motion. Dynamic friction coefficient and penetration depth curves during one tribological test were analysed indicating the moment when the coating exhibited first failure. The test has shown that tribological tests with low loads can be used for quality testing of thin coatings, including the influence of the mechanical surface preparation on the coating adhesion.
{"title":"TRIBOLOGICAL INVESTIGATION OF THE AUTOMOTIVE GRADE ALUMINIUM ALLOY WITH EPOXY PRIMER COATING","authors":"Nikola Kotorcevic, Nina Busarac, S. Nježić, D. Džunić, N. Grujovic, F. Živić","doi":"10.7251/comen2202204k","DOIUrl":"https://doi.org/10.7251/comen2202204k","url":null,"abstract":"Mechanical surface preparation is a common technique for removing contaminants from surface metal layers. Unlike chemical preparation, it does not require special safety measures, including those for disposal of by-products or toxic materials, thus making it more accessible for different industries. We investigated tribological testing as the experimental method to determine the quality of the coating and the influence of the initial mechanical surface treatment. Samples were made of aluminium alloy EN AW 5083 H111 that was shot blasted with white cast aluminium with resulting surface roughness of Rz=38.908 μm. Samples were further coated with Lankwitzer EvoCor 164 2-component epoxy primer. Tribological test realised on nanotribometer is described and output parameters have been analysed: friction coefficient and penetration depth. Ball-on-flat, dry contact tribological setup was used, with 100 mN normal load, under linear reciprocating motion. Dynamic friction coefficient and penetration depth curves during one tribological test were analysed indicating the moment when the coating exhibited first failure. The test has shown that tribological tests with low loads can be used for quality testing of thin coatings, including the influence of the mechanical surface preparation on the coating adhesion.","PeriodicalId":10617,"journal":{"name":"Contemporary Materials","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82692989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z. Stamenkovic, N. Nedeljkovic, V. Mirjanić, Z. Jezdić, Jovan Marković, V. Stojic
Severe skeletal Class III and facial asymmetry requires combined orthodontic and surgical procedure In order to correct of sagittal and transversal deviations between upper and lower jaw. Aim: The aim of this case was to present effects of combined orthodontic and surgical treatment on craniofacial morphology and whole facial aesthetics. Material and method: In this case a 17-year-old female patient years was treated. Patient had severe skeletal Class III caused by mandibular prognathism, latherognathism, open bite and crossbite. At the beginning of the treatment overbite was - 3.5mm and overjet - 6mm. Parameters on lateral cephalogram at the beginning of the orthodontic procedure were: SNA 83°, SNB 88°, ANB -5°, SN/SpP 9°, SN/MP 38°, SpP/MP 29°, sum of angles of Björk’s polygon 396°, Jarabak ratio 63.26%, I/SpP 47°, i/MP 98°. Orthodontic preparation for surgical treatment lasted 21 months with upper and lower fixed appliance. Surgical procedure was done on both jaws and lower wisdom teeth were extracted. Orthodontic treatment was finished 6 months after surgical intervention. Results and conclusion: Parameters on control lateral cephalogram at the end of treatment were: SNA 83°, SNB 85°, ANB -2°, SN/SpP 10°, SN/MP 32°, SpP/MP 22°, sum of angles of Björk’s polygon 394°, Jarabak ratio 64,20%, I/SpP 47°, i/MP 94°. Patient had stable occlusion in Class I with overjet 1.5mm and overbite 3mm. Both segment of treatment improved significantly facial aesthetics in profile and en face and provided correct occlusion in all three directions.
{"title":"COMBINED ORTHODONTIC AND SURGICAL TREATMENT IN PATIENT WITH CLASS III AND FACIAL ASYMMETRY","authors":"Z. Stamenkovic, N. Nedeljkovic, V. Mirjanić, Z. Jezdić, Jovan Marković, V. Stojic","doi":"10.7251/comen2202211s","DOIUrl":"https://doi.org/10.7251/comen2202211s","url":null,"abstract":"Severe skeletal Class III and facial asymmetry requires combined orthodontic and surgical procedure In order to correct of sagittal and transversal deviations between upper and lower jaw. Aim: The aim of this case was to present effects of combined orthodontic and surgical treatment on craniofacial morphology and whole facial aesthetics. Material and method: In this case a 17-year-old female patient years was treated. Patient had severe skeletal Class III caused by mandibular prognathism, latherognathism, open bite and crossbite. At the beginning of the treatment overbite was - 3.5mm and overjet - 6mm. Parameters on lateral cephalogram at the beginning of the orthodontic procedure were: SNA 83°, SNB 88°, ANB -5°, SN/SpP 9°, SN/MP 38°, SpP/MP 29°, sum of angles of Björk’s polygon 396°, Jarabak ratio 63.26%, I/SpP 47°, i/MP 98°. Orthodontic preparation for surgical treatment lasted 21 months with upper and lower fixed appliance. Surgical procedure was done on both jaws and lower wisdom teeth were extracted. Orthodontic treatment was finished 6 months after surgical intervention. Results and conclusion: Parameters on control lateral cephalogram at the end of treatment were: SNA 83°, SNB 85°, ANB -2°, SN/SpP 10°, SN/MP 32°, SpP/MP 22°, sum of angles of Björk’s polygon 394°, Jarabak ratio 64,20%, I/SpP 47°, i/MP 94°. Patient had stable occlusion in Class I with overjet 1.5mm and overbite 3mm. Both segment of treatment improved significantly facial aesthetics in profile and en face and provided correct occlusion in all three directions.","PeriodicalId":10617,"journal":{"name":"Contemporary Materials","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84835252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrijana Vukojević, Maria M. Savanović, Nataša Totić, S. Armaković, S. Pelemiš, Sanja J. Arma-Ković
Nadolol (NAD), one of the representatives of β-blockers, is used to treat cardiovascular diseases such as angina and hypertension. Due to its frequent use, it has been detected in hospital wastewater from which it is not removed efficiently enough, so it reaches natural waters. The lack of a satisfactorily efficient method for removing NAD from wastewater has created a need to find a more efficient way for its removal. This paper aims to investigate the efficiency of photocatalytic degradation of NAD by two TiO2-C nanocomposites with different carbon content (9 and 20 wt%) under UV radiation. The applied nanocomposites, synthesized by the sol-gel hydrothermal method, showed significant efficiency in removing NAD compared to direct photolysis. Also, the reaction rate constant, according to which the decomposition of NAD in the presence of TiO2-C takes place in the pseudo-first order, was calculated. The degradation of NAD was monitored by HPLC–PDA technique.
{"title":"REMOVAL OF NADOLOL USING COUPLED NANOMATERIALS BASED ON TITANIUM AND CARBON","authors":"Andrijana Vukojević, Maria M. Savanović, Nataša Totić, S. Armaković, S. Pelemiš, Sanja J. Arma-Ković","doi":"10.7251/comen2202127v","DOIUrl":"https://doi.org/10.7251/comen2202127v","url":null,"abstract":"Nadolol (NAD), one of the representatives of β-blockers, is used to treat cardiovascular diseases such as angina and hypertension. Due to its frequent use, it has been detected in hospital wastewater from which it is not removed efficiently enough, so it reaches natural waters. The lack of a satisfactorily efficient method for removing NAD from wastewater has created a need to find a more efficient way for its removal. This paper aims to investigate the efficiency of photocatalytic degradation of NAD by two TiO2-C nanocomposites with different carbon content (9 and 20 wt%) under UV radiation. The applied nanocomposites, synthesized by the sol-gel hydrothermal method, showed significant efficiency in removing NAD compared to direct photolysis. Also, the reaction rate constant, according to which the decomposition of NAD in the presence of TiO2-C takes place in the pseudo-first order, was calculated. The degradation of NAD was monitored by HPLC–PDA technique.","PeriodicalId":10617,"journal":{"name":"Contemporary Materials","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90227528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thanks to the in silico approach in drug design, the identification of new molecules is enabled and facilitated, as well as the optimization of the pharmacokinetics and toxicity of compounds obtained from different sources. Chromatographic methods, on the other hand, provide accurate and reliable information on the influence of the nature of substituents and applied organic modifiers on the pharmacological behavior of compounds, relying on the existence of similarities between intermolecular interactions that determine compound behavior in biological and chromatographic media. Barbituric acid derivatives were subjected to QSRR analysis and the parameters obtained by reversed phase thin layer chromatography (RP TLC18 F254s) were correlated with selected software-derived predictors of permeability, pharmacokinetics and toxicity using the method of linear regression. Тhus satisfactory mathematical models were obtained.
{"title":"QSRR DESCRIPTORS AS A TOOL IN THE STUDY OF THE BARBITURIC ACID DERIVATIVES’ BIOLOGICAL PROFILE","authors":"S. Apostolov, Ivana N. Stojiljković, Đ. Vaštag","doi":"10.7251/comen2202161a","DOIUrl":"https://doi.org/10.7251/comen2202161a","url":null,"abstract":"Thanks to the in silico approach in drug design, the identification of new molecules is enabled and facilitated, as well as the optimization of the pharmacokinetics and toxicity of compounds obtained from different sources. Chromatographic methods, on the other hand, provide accurate and reliable information on the influence of the nature of substituents and applied organic modifiers on the pharmacological behavior of compounds, relying on the existence of similarities between intermolecular interactions that determine compound behavior in biological and chromatographic media. Barbituric acid derivatives were subjected to QSRR analysis and the parameters obtained by reversed phase thin layer chromatography (RP TLC18 F254s) were correlated with selected software-derived predictors of permeability, pharmacokinetics and toxicity using the method of linear regression. Тhus satisfactory mathematical models were obtained.","PeriodicalId":10617,"journal":{"name":"Contemporary Materials","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82076331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria M. Savanović, Andrijana Vukojević, D. Marković, S. Armaković, S. Pelemiš, S. Armaković
Cefoperazone belongs to the third generation of cephalosporin antibiotics. It is accumulated in water due to its overuse and causes bacterial, environmental, and health issues. In this work, the efficiency of photocatalytic degradation of cefoperazone was studied using different types of radiation (simulated solar, UV, and LED) in the presence of different nanomaterials (ZnO and TiO2). First, the photolytic degradation of cefoperazone was examined, where UV radiation showed as most effective for cefoperazone degradation, wherein 29.5% of cefoperazone was degraded after 60 min. Photocatalysis in the presence of TiO2 leads to complete removal of cefoperazone after 30 min, while the use of ZnO leads to complete photocatalytic degradation of cefoperazone after 20 min using UV radiation. Simulated solar and LED radiation showed slightly lower efficiencies. When TiO2 was applied, the removal efficiency was around 60%, while approximately 70% of cefoperazone was degraded when ZnO was used.
{"title":"PHOTOCATALYTIC ACTIVITY OF ZnO AND TiO2 TOWARDS EFFECTIVE DEGRADATION OF CEFOPERAZONE","authors":"Maria M. Savanović, Andrijana Vukojević, D. Marković, S. Armaković, S. Pelemiš, S. Armaković","doi":"10.7251/comen2202133s","DOIUrl":"https://doi.org/10.7251/comen2202133s","url":null,"abstract":"Cefoperazone belongs to the third generation of cephalosporin antibiotics. It is accumulated in water due to its overuse and causes bacterial, environmental, and health issues. In this work, the efficiency of photocatalytic degradation of cefoperazone was studied using different types of radiation (simulated solar, UV, and LED) in the presence of different nanomaterials (ZnO and TiO2). First, the photolytic degradation of cefoperazone was examined, where UV radiation showed as most effective for cefoperazone degradation, wherein 29.5% of cefoperazone was degraded after 60 min. Photocatalysis in the presence of TiO2 leads to complete removal of cefoperazone after 30 min, while the use of ZnO leads to complete photocatalytic degradation of cefoperazone after 20 min using UV radiation. Simulated solar and LED radiation showed slightly lower efficiencies. When TiO2 was applied, the removal efficiency was around 60%, while approximately 70% of cefoperazone was degraded when ZnO was used.","PeriodicalId":10617,"journal":{"name":"Contemporary Materials","volume":"42 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83534708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
I. Hut, B. Jeftic, A. Dragicevic, L. Matija, D. Koruga
Cervical cancer screening with Papanicolaou test and liquid based cytology relies on the expertise of the pathologist. Liquid based cytology is proven to be more efficient than conventional Papanicolaou test when it comes to sample preparation and possibility of conducting several tests on the same sample. However, specificity and sensitivity of the test are in the range of the Papanicolaou test accuracy metrics, with false negative results still being the main drawback of these manually performed tests. Advances in technology and availability of digital data have enabled succesfull application of machine learning models in diagnostics. Images of cervical cells are now used as input to different deep learning models currently tested in studies concerning computer aided diagnostic systems. This study explores different architectures of convolutional neural network for cervical cancer detection based on Optomagnetic imaging spectroscopy and liquid based cytology samples. The proposed VGG16 based model achieved 93.3% sensitivity and 67.8% specificity in the binary classification problem. Results highlight the need for more balanced dataset in order for suggested deep model to achieve better performance.
{"title":"COMPUTER AIDED DIAGNOSTIC SYSTEM FOR WHOLE SLIDE IMAGE OF LIQUID BASED CERVICAL CYTOLOGY SAMPLE CLASSIFICATION USING CONVOLUTIONAL NEURAL NETWORK","authors":"I. Hut, B. Jeftic, A. Dragicevic, L. Matija, D. Koruga","doi":"10.7251/comen2202169h","DOIUrl":"https://doi.org/10.7251/comen2202169h","url":null,"abstract":"Cervical cancer screening with Papanicolaou test and liquid based cytology relies on the expertise of the pathologist. Liquid based cytology is proven to be more efficient than conventional Papanicolaou test when it comes to sample preparation and possibility of conducting several tests on the same sample. However, specificity and sensitivity of the test are in the range of the Papanicolaou test accuracy metrics, with false negative results still being the main drawback of these manually performed tests. Advances in technology and availability of digital data have enabled succesfull application of machine learning models in diagnostics. Images of cervical cells are now used as input to different deep learning models currently tested in studies concerning computer aided diagnostic systems. This study explores different architectures of convolutional neural network for cervical cancer detection based on Optomagnetic imaging spectroscopy and liquid based cytology samples. The proposed VGG16 based model achieved 93.3% sensitivity and 67.8% specificity in the binary classification problem. Results highlight the need for more balanced dataset in order for suggested deep model to achieve better performance.","PeriodicalId":10617,"journal":{"name":"Contemporary Materials","volume":"102 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77538923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Jeftic, I. Hut, I. Stanković, Jovana Šakota Rosić, L. Matija, Đ. Koruga
In order to further investigate performance of Optomagnetic Imaging Spectroscopy in cervical cancer detection, deep learning algorithm has been used for classification of optomagnetic spectra of the samples. Optomagnetic spectra reflect cell properties and based on those properties it is possible to differentiate normal cells from cells showing different levels of dysplasia and cancer cells. In one of the previous research, Optomagnetic imaging spectroscopy has demonstrated high percentages of accuracy, sensitivity and specificity in cervical cancer detection, particularly in the case of binary classification. Somewhat lower accuracy percentages were obtained in the case of four class classification. Compared to the results obtained by conventional machine learning classification algorithms, proposed deep learning algorithm achieves similar accuracy results (80%), greater sensitivity (83.3%), and comparable specificity percentages (78%).
{"title":"DEEP LEARNING ALGORITHM FOR CERVICAL CANCER DETECTION BASED ON IMAGES OF OPTOMAGNETIC SPECTRA","authors":"B. Jeftic, I. Hut, I. Stanković, Jovana Šakota Rosić, L. Matija, Đ. Koruga","doi":"10.7251/comen2202178j","DOIUrl":"https://doi.org/10.7251/comen2202178j","url":null,"abstract":"In order to further investigate performance of Optomagnetic Imaging Spectroscopy in cervical cancer detection, deep learning algorithm has been used for classification of optomagnetic spectra of the samples. Optomagnetic spectra reflect cell properties and based on those properties it is possible to differentiate normal cells from cells showing different levels of dysplasia and cancer cells. In one of the previous research, Optomagnetic imaging spectroscopy has demonstrated high percentages of accuracy, sensitivity and specificity in cervical cancer detection, particularly in the case of binary classification. Somewhat lower accuracy percentages were obtained in the case of four class classification. Compared to the results obtained by conventional machine learning classification algorithms, proposed deep learning algorithm achieves similar accuracy results (80%), greater sensitivity (83.3%), and comparable specificity percentages (78%).","PeriodicalId":10617,"journal":{"name":"Contemporary Materials","volume":"51 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89596339","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：