Pub Date : 2025-02-01DOI: 10.1016/j.crad.2024.106786
H.-J. Tu , Q.-Q. Chen , X. Chen , J.-C. Tu , J.-T. Cao , F. Zhu , C.-H. Hu
AIM
To assess transmural remission in patients with Crohn's disease using low-dose small bowel computed tomography (CT) perfusion scans.
MATERIALS AND METHODS
Forty six patients were divided into active and remission phases based on Crohn's Disease Activity Index (CDAI) and C-reactive protein (CRP). Dual-source CT enterography with low-dose perfusion scans was conducted to generate perfusion parameter maps, including blood flow (BF), blood volume (BV), time to peak (TTP), mean transit time (MTT), and permeability of surface (PS). We compared differences in perfusion parameter values of intestinal walls, mesenteric fat, and lymph nodes between two groups. Receiver operating characteristic (ROC) curves were plotted, and area under the curve (AUC), sensitivity, specificity, and cutoff values were calculated.
RESULTS
The BF, BV, TTP, MTT, and PS values of the intestinal wall were significantly higher in the active phase (P0.05). Additionally, lymph node BF and TTP displayed significant differences (P<0.01).
CONCLUSION
Dual-source CT enterography with low-dose perfusion scans enables quantitative assessment of Crohn's disease microcirculation in intestinal walls, mesenteric fat, and lymph nodes. These quantitative indicators provide strong diagnostic efficacy and offer insights into whether the disease is in transmural remission.
{"title":"Quantitative assessment of transmural remission in Crohn's disease using low dose computed tomography (CT) enterography perfusion imaging: a single-centre study based on intestinal microcirculation","authors":"H.-J. Tu , Q.-Q. Chen , X. Chen , J.-C. Tu , J.-T. Cao , F. Zhu , C.-H. Hu","doi":"10.1016/j.crad.2024.106786","DOIUrl":"10.1016/j.crad.2024.106786","url":null,"abstract":"<div><h3>AIM</h3><div>To assess transmural remission in patients with Crohn's disease using low-dose small bowel computed tomography (CT) perfusion scans.</div></div><div><h3>MATERIALS AND METHODS</h3><div>Forty six patients were divided into active and remission phases based on Crohn's Disease Activity Index (CDAI) and C-reactive protein (CRP). Dual-source CT enterography with low-dose perfusion scans was conducted to generate perfusion parameter maps, including blood flow (BF), blood volume (BV), time to peak (TTP), mean transit time (MTT), and permeability of surface (PS). We compared differences in perfusion parameter values of intestinal walls, mesenteric fat, and lymph nodes between two groups. Receiver operating characteristic (ROC) curves were plotted, and area under the curve (AUC), sensitivity, specificity, and cutoff values were calculated.</div></div><div><h3>RESULTS</h3><div>The BF, BV, TTP, MTT, and PS values of the intestinal wall were significantly higher in the active phase (P0.05). Additionally, lymph node BF and TTP displayed significant differences (P<0.01).</div></div><div><h3>CONCLUSION</h3><div>Dual-source CT enterography with low-dose perfusion scans enables quantitative assessment of Crohn's disease microcirculation in intestinal walls, mesenteric fat, and lymph nodes. These quantitative indicators provide strong diagnostic efficacy and offer insights into whether the disease is in transmural remission.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"Article 106786"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142969043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.crad.2024.09.018
M. Alakhras , D.S. Al-Mousa , B. Al Mohammad , I. Kleib
Aim
To evaluate radiation dose among physicians, nurses, nuclear medicine (NM) technicians, and radiographers at a single institution and to compare the difference in the measured dose during COVID-19 with other periods.
Materials and Methods
A retrospective analysis of the occupational radiation doses received by all workers in diagnostic radiography and NM departments at a single institution during a 5-year period (2018–2022) was performed. Dose measurements were recorded for 94 radiology personnel: radiographers, NM technicians, physicians, and nurses. In addition to descriptive statistics, the Mann–Whitney U-test was used to compare the average annual effective dose between male and female workers and between the periods before and during COVID-19. Kruskal–Wallis test was used to compare effective radiation doses from different quadrants.
Results
The annual average effective doses were found to be between 0.58 and 0.72 mSv for males and 0.68 and 0.85 mSv for females. All radiographers, 86% of nurses, and 69% of physicians have received annual average effective doses below 0.99 mSv. The average annual effective doses for all radiation workers were similar in the period before COVID-19 when compared to the period during COVID-19 except for nurses who had significantly lower (P<0.05) doses before COVID-19.
Conclusion
The average annual effective doses of radiation workers during 2018–2022 were well below the annual dose limit. A relatively higher average effective dose was received among NM technicians compared with other radiation occupational workers. While the caseload during the COVID-19 pandemic was lower due to government policies, the radiation dose to healthcare workers during the pandemic was similar to that before the pandemic.
{"title":"Radiation dose to health care workers measured by thermoluminescent dosimetry","authors":"M. Alakhras , D.S. Al-Mousa , B. Al Mohammad , I. Kleib","doi":"10.1016/j.crad.2024.09.018","DOIUrl":"10.1016/j.crad.2024.09.018","url":null,"abstract":"<div><h3>Aim</h3><div>To evaluate radiation dose among physicians, nurses, nuclear medicine (NM) technicians, and radiographers at a single institution and to compare the difference in the measured dose during COVID-19 with other periods.</div></div><div><h3>Materials and Methods</h3><div>A retrospective analysis of the occupational radiation doses received by all workers in diagnostic radiography and NM departments at a single institution during a 5-year period (2018–2022) was performed. Dose measurements were recorded for 94 radiology personnel: radiographers, NM technicians, physicians, and nurses. In addition to descriptive statistics, the Mann–Whitney U-test was used to compare the average annual effective dose between male and female workers and between the periods before and during COVID-19. Kruskal–Wallis test was used to compare effective radiation doses from different quadrants.</div></div><div><h3>Results</h3><div>The annual average effective doses were found to be between 0.58 and 0.72 mSv for males and 0.68 and 0.85 mSv for females. All radiographers, 86% of nurses, and 69% of physicians have received annual average effective doses below 0.99 mSv. The average annual effective doses for all radiation workers were similar in the period before COVID-19 when compared to the period during COVID-19 except for nurses who had significantly lower (P<0.05) doses before COVID-19.</div></div><div><h3>Conclusion</h3><div>The average annual effective doses of radiation workers during 2018–2022 were well below the annual dose limit. A relatively higher average effective dose was received among NM technicians compared with other radiation occupational workers. While the caseload during the COVID-19 pandemic was lower due to government policies, the radiation dose to healthcare workers during the pandemic was similar to that before the pandemic.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"Article 106712"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142496503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.crad.2024.106776
M. Puseljic , D. Prunea , G. Toth-Gayor , A. Dutschke , A. Schmidt , J. Schmid , C. Stark , M. Fuchsjäger , P. Apfaltrer
Aim
To assess the diagnostic potential of a noncoronary-dedicated pre-TAVR CT angiography (CTA) conducted as a prospective ECG-gated scan without premedication and standard cardiac reconstructions in evaluating bystander coronary artery disease (CAD) against invasive coronary angiography (ICA) as the gold standard.
Materials and Methods
This retrospective study included 232 patients who underwent both CTA and ICA as part of their pre-TAVR evaluation. Exclusion criteria included prior stent, pacemaker, coronary artery bypass, or valve surgery. Coronary arteries were analysed solely through thin-slice axial reconstructions, with observers blinded to ICA results. Stenosis was categorised as mild (< 50%), moderate (50%–69%), or severe (≥70%). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy were calculated for 50% and 70% diameter stenosis (DS) thresholds.
Results
At the 50% DS threshold, CTA demonstrated 71% sensitivity, 74% specificity, 92% NPV, and 38% PPV. At the 70% DS threshold, results included 46% sensitivity, 91% specificity, 93% NPV, and 41% PPV. The highest vessel-specific NPV at 50% DS was for the left main (98%) and left anterior descending (LAD) (91%); at 70% DS, left main (LM) (98%) and left circumflex (LCX) (94%) showed the highest NPV. Image quality impacted NPV, with excellent or very good image quality linked to higher diagnostic performance.
Conclusion
Noncoronary-dedicated pre-TAVR CTA shows promise for ruling out significant CAD effectively and may act as a gatekeeper for ICA, aligning with typical coronary CT angiography (CCTA) outcomes.
{"title":"Assessment of bystander coronary artery disease in transcatheter aortic valve replacement (TAVR) patients using noncoronary-dedicated planning computed tomography angiography (CTA): diagnostic accuracy in a retrospective real-world cohort","authors":"M. Puseljic , D. Prunea , G. Toth-Gayor , A. Dutschke , A. Schmidt , J. Schmid , C. Stark , M. Fuchsjäger , P. Apfaltrer","doi":"10.1016/j.crad.2024.106776","DOIUrl":"10.1016/j.crad.2024.106776","url":null,"abstract":"<div><h3>Aim</h3><div>To assess the diagnostic potential of a noncoronary-dedicated pre-TAVR CT angiography (CTA) conducted as a prospective ECG-gated scan without premedication and standard cardiac reconstructions in evaluating bystander coronary artery disease (CAD) against invasive coronary angiography (ICA) as the gold standard.</div></div><div><h3>Materials and Methods</h3><div>This retrospective study included 232 patients who underwent both CTA and ICA as part of their pre-TAVR evaluation. Exclusion criteria included prior stent, pacemaker, coronary artery bypass, or valve surgery. Coronary arteries were analysed solely through thin-slice axial reconstructions, with observers blinded to ICA results. Stenosis was categorised as mild (< 50%), moderate (50%–69%), or severe (≥70%). Sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and diagnostic accuracy were calculated for 50% and 70% diameter stenosis (DS) thresholds.</div></div><div><h3>Results</h3><div>At the 50% DS threshold, CTA demonstrated 71% sensitivity, 74% specificity, 92% NPV, and 38% PPV. At the 70% DS threshold, results included 46% sensitivity, 91% specificity, 93% NPV, and 41% PPV. The highest vessel-specific NPV at 50% DS was for the left main (98%) and left anterior descending (LAD) (91%); at 70% DS, left main (LM) (98%) and left circumflex (LCX) (94%) showed the highest NPV. Image quality impacted NPV, with excellent or very good image quality linked to higher diagnostic performance.</div></div><div><h3>Conclusion</h3><div>Noncoronary-dedicated pre-TAVR CTA shows promise for ruling out significant CAD effectively and may act as a gatekeeper for ICA, aligning with typical coronary CT angiography (CCTA) outcomes.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"Article 106776"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142964123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.crad.2024.09.010
D. Togher , G. Dean , J. Moon , R. Mayola , A. Medina , J. Repec , M. Meheux , S. Mather , M. Storey , S. Rickaby , M.Z. Abubacker , S.C. Shelmerdine
Aims
To investigate radiology staff perceptions of an AI tool for chest radiography triage, flagging findings suspicious for lung cancer to expedite same-day CT chest examination studies.
Materials and Methods
Surveys were distributed to all radiology staff at three time points: at pre-implementation, one month and also seven months post-implementation of artificial intelligence (AI). Survey questions captured feedback on AI use and patient impact.
Results
Survey response rates at the three time periods were 23.1% (45/195), 14.9% (29/195) and 27.2% (53/195), respectively. Most respondents initially anticipated AI to be time-saving for the department and patient (50.8%), but this shifted to faster follow-up care for patients after AI implementation (51.7%). From the free text comments, early apprehension about job role changes evolved into frustration regarding technical integration challenges after implementation. This later transitioned to a more balanced view of recognised patient benefits versus minor ongoing logistical issues by the late post-implementation stage. There was majority disagreement across all survey periods that AI could be considered to be used autonomously (53.3–72.5%), yet acceptance grew for personal AI usage if staff were to be patients themselves (from 31.1% pre-implementation to 47.2% post-implementation).
Conclusion
Successful AI integration in radiology demands active staff engagement, addressing concerns to transform initial mixed excitement and resistance into constructive adaptation. Continual feedback is vital for refining AI deployment strategies, ensuring its beneficial and sustainable incorporation into clinical care pathways.
{"title":"Evolution of radiology staff perspectives during artificial intelligence (AI) implementation for expedited lung cancer triage","authors":"D. Togher , G. Dean , J. Moon , R. Mayola , A. Medina , J. Repec , M. Meheux , S. Mather , M. Storey , S. Rickaby , M.Z. Abubacker , S.C. Shelmerdine","doi":"10.1016/j.crad.2024.09.010","DOIUrl":"10.1016/j.crad.2024.09.010","url":null,"abstract":"<div><h3>Aims</h3><div>To investigate radiology staff perceptions of an AI tool for chest radiography triage, flagging findings suspicious for lung cancer to expedite same-day CT chest examination studies.</div></div><div><h3>Materials and Methods</h3><div>Surveys were distributed to all radiology staff at three time points: at pre-implementation, one month and also seven months post-implementation of artificial intelligence (AI). Survey questions captured feedback on AI use and patient impact.</div></div><div><h3>Results</h3><div>Survey response rates at the three time periods were 23.1% (45/195), 14.9% (29/195) and 27.2% (53/195), respectively. Most respondents initially anticipated AI to be time-saving for the department and patient (50.8%), but this shifted to faster follow-up care for patients after AI implementation (51.7%). From the free text comments, early apprehension about job role changes evolved into frustration regarding technical integration challenges after implementation. This later transitioned to a more balanced view of recognised patient benefits versus minor ongoing logistical issues by the late post-implementation stage. There was majority disagreement across all survey periods that AI could be considered to be used autonomously (53.3–72.5%), yet acceptance grew for personal AI usage if staff were to be patients themselves (from 31.1% pre-implementation to 47.2% post-implementation).</div></div><div><h3>Conclusion</h3><div>Successful AI integration in radiology demands active staff engagement, addressing concerns to transform initial mixed excitement and resistance into constructive adaptation. Continual feedback is vital for refining AI deployment strategies, ensuring its beneficial and sustainable incorporation into clinical care pathways.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"Article 106704"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142496491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.crad.2024.106760
N. Li , Y. Cao , Y. Li , K. Zhang , L. Zhang , Q. Luo , W. Sun , H. Shi
AIM
To investigate the relationship between epicardial adipose tissue (EAT) and myocardial strain and the severity of coronary artery disease (CAD), and to evaluate the predictive value of EAT parameters in early left ventricular (LV) diastolic dysfunction.
MATERIALS AND METHODS
One hundred seventy patients with suspected CAD who underwent both coronary computed tomography angiography and echocardiography were enrolled in 2020. LV global strains were calculated using commercial software. Epicardial adipose tissue was defined as adipose tissue between -190 HU and -30 HU in the visceral pericardium from the level of pulmonary artery bifurcation to the apical level. EAT volume and average attenuation values were measured. LV diastolic dysfunction was determined by echocardiography.
RESULTS
The mean age of the participants was 56.65 ± 12.64 years, and 57.65% were male. EAT volume and mean attenuation values were significantly correlated with CAD severity. EAT volume was significantly positively correlated with global longitudinal strain (GLS) (r=0.313, P<0.01), and EAT attenuation values were positively correlated with global circumferential strain and GLS (r=0.236, 0.164, respectively, both P<0.05). Age (β = 0.125, OR = 1.134, P<0.01) and EAT volume (β = 0.019, OR = 1.019, P=0.018) were independent predictors of LV diastolic dysfunction. Age combined with EAT volume improved the diagnostic efficacy of left ventricular diastolic dysfunction.
CONCLUSION
EAT parameters can reflect the severity of CAD. EAT volume is capable of predicting early LV diastolic dysfunction. Compared with GLS, EAT volume may be able to predict LV diastolic dysfunction earlier.
{"title":"Predictive value of epicardial adipose tissue volume for early detection of left ventricular dysfunction in patients suspected of coronary artery disease","authors":"N. Li , Y. Cao , Y. Li , K. Zhang , L. Zhang , Q. Luo , W. Sun , H. Shi","doi":"10.1016/j.crad.2024.106760","DOIUrl":"10.1016/j.crad.2024.106760","url":null,"abstract":"<div><h3>AIM</h3><div>To investigate the relationship between epicardial adipose tissue (EAT) and myocardial strain and the severity of coronary artery disease (CAD), and to evaluate the predictive value of EAT parameters in early left ventricular (LV) diastolic dysfunction.</div></div><div><h3>MATERIALS AND METHODS</h3><div>One hundred seventy patients with suspected CAD who underwent both coronary computed tomography angiography and echocardiography were enrolled in 2020. LV global strains were calculated using commercial software. Epicardial adipose tissue was defined as adipose tissue between -190 HU and -30 HU in the visceral pericardium from the level of pulmonary artery bifurcation to the apical level. EAT volume and average attenuation values were measured. LV diastolic dysfunction was determined by echocardiography.</div></div><div><h3>RESULTS</h3><div>The mean age of the participants was 56.65 ± 12.64 years, and 57.65% were male. EAT volume and mean attenuation values were significantly correlated with CAD severity. EAT volume was significantly positively correlated with global longitudinal strain (GLS) (r=0.313, P<0.01), and EAT attenuation values were positively correlated with global circumferential strain and GLS (r=0.236, 0.164, respectively, both P<0.05). Age (<em>β</em> = 0.125, OR = 1.134, P<0.01) and EAT volume (<em>β</em> = 0.019, OR = 1.019, P=0.018) were independent predictors of LV diastolic dysfunction. Age combined with EAT volume improved the diagnostic efficacy of left ventricular diastolic dysfunction.</div></div><div><h3>CONCLUSION</h3><div>EAT parameters can reflect the severity of CAD. EAT volume is capable of predicting early LV diastolic dysfunction. Compared with GLS, EAT volume may be able to predict LV diastolic dysfunction earlier.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"Article 106760"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.crad.2024.106769
M. Wu , Z. Xu , Q. Huang , J. Shi , K. Zhou , Y. Hong , Y. Zhan , N. Zhou
Aim
Coronary artery disease (CAD) is a primary cause of mortality, prompting ongoing research into noninvasive diagnostic modalities. This study aimed to evaluate the diagnostic efficacy of exercise electrocardiography testing (EET) combined with cadmium zinc tellurium cardiac-dedicated single photon emission computed tomography (CZT-SPECT) imaging for CAD.
Materials and Methods
CZT-SPECT and EET were examined in 124 patients aged 20–85 years, followed by coronary angiography to evaluate the sensitivity, specificity, positive predictive value, and negative predictive value of EET/CZT-SPECT alone and in combination. CAD was defined as the presence of > 50% stenosis at the time of coronary angiography.
Results
The sensitivity of the EET test alone was 31.58%, the specificity was 80%, the positive predictive value (PPV) was 22.22%, and the negative predictive value (NPV) was 86.6%. The corresponding values of CZT-SPECT alone were 36.07%, 92.06%, 81.48% and 59.79%, respectively. The combined results showed that the sensitivity, specificity, PPV, and NPV were 60.00%, 90.57%, 54.55%, and 92.31%, respectively. In this study, the positive likelihood ratio (PLR) diagnosed with EET alone was 1.58, the PLR diagnosed with CZT-SPECT alone was 4.54, and the PLR diagnosed with combination was 6.36.
Conclusion
The combination of CZT-SPECT and EET showed significantly improved CAD diagnostic accuracy compared with either approach alone.
{"title":"Exercise electrocardiogram combined with cadmium zinc tellurium (CZT) cardiac-dedicated single photon emission computed tomography (SPECT) predicts coronary artery disease","authors":"M. Wu , Z. Xu , Q. Huang , J. Shi , K. Zhou , Y. Hong , Y. Zhan , N. Zhou","doi":"10.1016/j.crad.2024.106769","DOIUrl":"10.1016/j.crad.2024.106769","url":null,"abstract":"<div><h3>Aim</h3><div>Coronary artery disease (CAD) is a primary cause of mortality, prompting ongoing research into noninvasive diagnostic modalities. This study aimed to evaluate the diagnostic efficacy of exercise electrocardiography testing (EET) combined with cadmium zinc tellurium cardiac-dedicated single photon emission computed tomography (CZT-SPECT) imaging for CAD.</div></div><div><h3>Materials and Methods</h3><div>CZT-SPECT and EET were examined in 124 patients aged 20–85 years, followed by coronary angiography to evaluate the sensitivity, specificity, positive predictive value, and negative predictive value of EET/CZT-SPECT alone and in combination. CAD was defined as the presence of > 50% stenosis at the time of coronary angiography.</div></div><div><h3>Results</h3><div>The sensitivity of the EET test alone was 31.58%, the specificity was 80%, the positive predictive value (PPV) was 22.22%, and the negative predictive value (NPV) was 86.6%. The corresponding values of CZT-SPECT alone were 36.07%, 92.06%, 81.48% and 59.79%, respectively. The combined results showed that the sensitivity, specificity, PPV, and NPV were 60.00%, 90.57%, 54.55%, and 92.31%, respectively. In this study, the positive likelihood ratio (PLR) diagnosed with EET alone was 1.58, the PLR diagnosed with CZT-SPECT alone was 4.54, and the PLR diagnosed with combination was 6.36.</div></div><div><h3>Conclusion</h3><div>The combination of CZT-SPECT and EET showed significantly improved CAD diagnostic accuracy compared with either approach alone.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"Article 106769"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.crad.2024.09.006
Y. Fang , Y. Sun , T. Lai , X. Song , T. Hu , Y. Zhao , Y. Lin , Q. Bao
Aim
Various magnetic resonance imaging (MRI) sequences can be utilized to visualize human meningeal lymphatic vessels (MLVs) for investigating the associations between MLVs and central nervous system (CNS) disorders. This study aimed to compare the quality of contrast-enhanced 3D-T2WI and 3D-T2-fluid-attenuated inversion recovery (FLAIR) MRI sequences to display human MLVs.
Materials and Methods
Sixty-two patients (27 males, 35 females; mean age 55.8 ± 14.9 years) underwent 3D-T2WI and 3D-T2-FLAIR scan in combination with Gd-DTPA injection to show MLVs.
Results
(1) The positivity rates of the 3D-T2WI sequence were 98.4%, 29.0%, and 46.8%, around the dural sinus, middle meningeal artery, and ethmoid sinus, respectively. The positivity rates of the 3D-T2-FLAIR sequence were 100%, 48.4%, and 66.1%, respectively. The positivity rate was significantly higher with the 3D-T2-FLAIR sequence compared with the 3D-T2WI sequence for the middle meningeal artery and ethmoid sinus regions (p < 0.05). (2) In patients with brain lesions and intracranial space-occupying lesions, the positivity rate was significantly higher with the 3D-T2-FLAIR sequence compared with the 3D-T2WI sequence for the middle meningeal artery and ethmoid sinus regions (p < 0.05). (3) The mean cross-sectional areas of MLVs around the dural sinus, middle meningeal artery, and ethmoid sinus were all higher using the 3D-T2-FLAIR sequence compared with the 3D-T2WI sequence at all three sites (p < 0.01). (4) The signal intensity was significantly higher using the 3D-T2-FLAIR sequence compared with the 3D-T2WI sequence around the dural sinus and ethmoid sinus (p < 0.001).
Conclusion
The 3D-T2-FLAIR sequence contrast-enhanced scan showed superior visualization of MLVs compared with the 3D-T2WI sequence.
{"title":"Comparative study of 3D-T2WI vs. 3D-T2-FLAIR MRI in displaying human meningeal lymphatics vessels","authors":"Y. Fang , Y. Sun , T. Lai , X. Song , T. Hu , Y. Zhao , Y. Lin , Q. Bao","doi":"10.1016/j.crad.2024.09.006","DOIUrl":"10.1016/j.crad.2024.09.006","url":null,"abstract":"<div><h3>Aim</h3><div>Various magnetic resonance imaging (MRI) sequences can be utilized to visualize human meningeal lymphatic vessels (MLVs) for investigating the associations between MLVs and central nervous system (CNS) disorders. This study aimed to compare the quality of contrast-enhanced 3D-T2WI and 3D-T2-fluid-attenuated inversion recovery (FLAIR) MRI sequences to display human MLVs.</div></div><div><h3>Materials and Methods</h3><div>Sixty-two patients (27 males, 35 females; mean age 55.8 ± 14.9 years) underwent 3D-T2WI and 3D-T2-FLAIR scan in combination with Gd-DTPA injection to show MLVs.</div></div><div><h3>Results</h3><div>(1) The positivity rates of the 3D-T2WI sequence were 98.4%, 29.0%, and 46.8%, around the dural sinus, middle meningeal artery, and ethmoid sinus, respectively. The positivity rates of the 3D-T2-FLAIR sequence were 100%, 48.4%, and 66.1%, respectively. The positivity rate was significantly higher with the 3D-T2-FLAIR sequence compared with the 3D-T2WI sequence for the middle meningeal artery and ethmoid sinus regions (<em>p</em> < 0.05). (2) In patients with brain lesions and intracranial space-occupying lesions, the positivity rate was significantly higher with the 3D-T2-FLAIR sequence compared with the 3D-T2WI sequence for the middle meningeal artery and ethmoid sinus regions (<em>p</em> < 0.05). (3) The mean cross-sectional areas of MLVs around the dural sinus, middle meningeal artery, and ethmoid sinus were all higher using the 3D-T2-FLAIR sequence compared with the 3D-T2WI sequence at all three sites (<em>p</em> < 0.01). (4) The signal intensity was significantly higher using the 3D-T2-FLAIR sequence compared with the 3D-T2WI sequence around the dural sinus and ethmoid sinus (<em>p</em> < 0.001).</div></div><div><h3>Conclusion</h3><div>The 3D-T2-FLAIR sequence contrast-enhanced scan showed superior visualization of MLVs compared with the 3D-T2WI sequence.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"81 ","pages":"Article 106700"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142496489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-01DOI: 10.1016/j.crad.2025.106836
M. Cellina , M. Cè , E. Grimaldi , G. Mastellone , A. Fortunati , G. Oliva , C. Martinenghi , G. Carrafiello
Dual-energy computed tomography (DECT) has become an essential tool in emergency radiology, significantly enhancing diagnostic capabilities for a variety of acute conditions. By utilising two distinct X-ray energy spectra, DECT differentiates materials based on their attenuation properties, providing detailed insights into tissue composition and pathology.
In emergency settings, DECT is used in thoracic imaging for the detection of pulmonary embolism, in abdominal imaging to enhance the diagnosis and characterisation of conditions such as pancreatitis, appendicitis, gastrointestinal bleeding, and bowel ischaemia and in the genitourinary system for identifying kidney stones, pyelonephritis, and urinary bleeding.
In neuroimaging, DECT enables image optimisation through virtual monochromatic images and the reduction of metal artifacts. It helps in the differential diagnosis of haemorrhage versus tumour-related haemorrhage, haemorrhage versus contrast extravasation, and in the dating of vertebral collapse.
DECT offers several advantages, including enhanced visualisation, the potential to reduce radiation exposure and contrast medium, and improved diagnostic accuracy across a wide range of conditions. However, its routine clinical adoption is still evolving due to challenges such as limited availability, cost, and the need for specialised training.
This pictorial essay aims to encourage the broader integration of DECT into emergency imaging protocols by showcasing its clinical applications and benefits.
{"title":"The role of dual-energy computed tomography (DECT) in emergency radiology: a visual guide to advanced diagnostics","authors":"M. Cellina , M. Cè , E. Grimaldi , G. Mastellone , A. Fortunati , G. Oliva , C. Martinenghi , G. Carrafiello","doi":"10.1016/j.crad.2025.106836","DOIUrl":"10.1016/j.crad.2025.106836","url":null,"abstract":"<div><div>Dual-energy computed tomography (DECT) has become an essential tool in emergency radiology, significantly enhancing diagnostic capabilities for a variety of acute conditions. By utilising two distinct X-ray energy spectra, DECT differentiates materials based on their attenuation properties, providing detailed insights into tissue composition and pathology.</div><div>In emergency settings, DECT is used in thoracic imaging for the detection of pulmonary embolism, in abdominal imaging to enhance the diagnosis and characterisation of conditions such as pancreatitis, appendicitis, gastrointestinal bleeding, and bowel ischaemia and in the genitourinary system for identifying kidney stones, pyelonephritis, and urinary bleeding.</div><div>In neuroimaging, DECT enables image optimisation through virtual monochromatic images and the reduction of metal artifacts. It helps in the differential diagnosis of haemorrhage versus tumour-related haemorrhage, haemorrhage versus contrast extravasation, and in the dating of vertebral collapse.</div><div>DECT offers several advantages, including enhanced visualisation, the potential to reduce radiation exposure and contrast medium, and improved diagnostic accuracy across a wide range of conditions. However, its routine clinical adoption is still evolving due to challenges such as limited availability, cost, and the need for specialised training.</div><div>This pictorial essay aims to encourage the broader integration of DECT into emergency imaging protocols by showcasing its clinical applications and benefits.</div></div>","PeriodicalId":10695,"journal":{"name":"Clinical radiology","volume":"83 ","pages":"Article 106836"},"PeriodicalIF":2.1,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143529206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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