This study aimed to examine the effects of four-weeks high-intensity interval training (HIIT) on fat oxidation responses during submaximal exercise in active young men. For this purpose, 20 active young men (who participated in the exercise three times per week) were divided into two groups, including a training group (age: 19.3±0.48 years, V̇O2peak 2.9±0.35 l/min, n=10) and a control group (age: 19.7±0.67 years, V̇O2peak 2.7±0.26 l/min, n=10). The training group performed high-intensity interval training for three sessions per week. Specifically, each session included 8-11 intensive cycling efforts comprising of 60 s duration. A 75 s low pedalling rate (30 W) was used as an active recovery between the intervals. Furthermore, a V̇O2peak test was performed prior to, at the end of two weeks and after the training period. Also, a 60 min constant cycling protocol was performed at ~60% V̇O2peak, in addition to the V̇O2peak test, before and after the training protocol. To assess plasma free fatty acids and glucose, blood samples were taken during a 60-min aerobic exercise prior to and following the training period. An increase (17.8%) in V̇O2peak was observed for the HIIT group after the training period compared to the control group (P<0.05). The HIIT group performed the 60 min sub-maximal exercise test at a lower percentage of V̇O2peak, and decreases in the respiratory exchange ratio were greater in the HIIT group than in the control group (P<0.05). Compared to the pre-test values and control group results, the HIIT group used less carbohydrate and more lipid oxidation during submaximal exercise (P<0.05). The present study’s results indicate that short-term low volume HIIT can increase aerobic capacity and fat oxidation during submaximal exercise.
本研究旨在研究为期四周的高强度间歇训练(HIIT)对活跃年轻男性在亚极限运动期间脂肪氧化反应的影响。为此，将20名活跃的年轻男性(每周运动3次)分为两组，一组为训练组(年龄:19.3±0.48岁，V值峰值2.9±0.35 l/min, n=10)，另一组为对照组(年龄:19.7±0.67岁，V值峰值2.7±0.26 l/min, n=10)。训练组每周进行三次高强度间歇训练。具体来说，每次训练包括8-11次高强度骑行，持续时间为60秒。采用75 s的低蹬车速率(30 W)作为间隔间的主动恢复。此外，在训练开始前、两周结束时和训练结束后分别进行V²o2峰值测试。此外，在训练方案之前和之后，除了进行V o 2峰值测试外，还进行了~60% V o 2峰值下的60分钟恒定循环方案。为了评估血浆游离脂肪酸和葡萄糖，在训练前后进行60分钟的有氧运动时采集血液样本。训练结束后，HIIT组与对照组相比，V / o2峰值升高17.8% (P<0.05)。HIIT组以较低的V / o峰值百分比进行60 min亚极限运动试验，呼吸交换率的下降幅度大于对照组(P<0.05)。与测试前值和对照组结果相比，HIIT组在亚极限运动中使用的碳水化合物更少，脂质氧化更多(P<0.05)。目前的研究结果表明，短期低容量HIIT可以增加亚极限运动期间的有氧能力和脂肪氧化。
{"title":"High-intensity interval training improves fat oxidation during submaximal exercise in active young men","authors":"A. Ahmadi, H. Rajabi, J. Baker","doi":"10.3920/cep210028","DOIUrl":"https://doi.org/10.3920/cep210028","url":null,"abstract":"This study aimed to examine the effects of four-weeks high-intensity interval training (HIIT) on fat oxidation responses during submaximal exercise in active young men. For this purpose, 20 active young men (who participated in the exercise three times per week) were divided into two groups, including a training group (age: 19.3±0.48 years, V̇O2peak 2.9±0.35 l/min, n=10) and a control group (age: 19.7±0.67 years, V̇O2peak 2.7±0.26 l/min, n=10). The training group performed high-intensity interval training for three sessions per week. Specifically, each session included 8-11 intensive cycling efforts comprising of 60 s duration. A 75 s low pedalling rate (30 W) was used as an active recovery between the intervals. Furthermore, a V̇O2peak test was performed prior to, at the end of two weeks and after the training period. Also, a 60 min constant cycling protocol was performed at ~60% V̇O2peak, in addition to the V̇O2peak test, before and after the training protocol. To assess plasma free fatty acids and glucose, blood samples were taken during a 60-min aerobic exercise prior to and following the training period. An increase (17.8%) in V̇O2peak was observed for the HIIT group after the training period compared to the control group (P<0.05). The HIIT group performed the 60 min sub-maximal exercise test at a lower percentage of V̇O2peak, and decreases in the respiratory exchange ratio were greater in the HIIT group than in the control group (P<0.05). Compared to the pre-test values and control group results, the HIIT group used less carbohydrate and more lipid oxidation during submaximal exercise (P<0.05). The present study’s results indicate that short-term low volume HIIT can increase aerobic capacity and fat oxidation during submaximal exercise.","PeriodicalId":10709,"journal":{"name":"Comparative Exercise Physiology","volume":"381 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76765692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study aimed to evaluate the effect of four weeks of aerobic exercise training combined with probiotic supplementation on mRNA levels of Nrf-2 and caspase-3 genes, superoxide dismutase (SOD), and serum total antioxidant capacity (TAC) in rats with type 2 diabetes. 40 male Wistar diabetic rats were divided into five groups: healthy placebo control group (NC), diabetic control group without supplement (DC), diabetic control group with supplement (SDC), diabetic aerobic training group without supplement (DT), and diabetic aerobic training group with probiotic supplement (SDT). Each training group performed training five days per week for four weeks and each session of training consisted of 30 min running on a treadmill with an intensity of 65-60% of maximum speed. Simultaneously, rats were fed probiotic supplements. Serum glucose, SOD, and TAC were analysed. The real-time PCR technique was used to determine the gene expression of Nrf-2 and caspase-3. Both aerobic exercise training and probiotic supplementation interactively reduced caspase 3 gene expression, increased Nrf-2 gene expression and enhanced TAC in the left ventricle of diabetic rats. Also, the reduction of caspase-3 mRNA in the left ventricle was more effective in the SDT group than in other diabetic groups. There was no interaction effect on SOD. However, a simultaneous effect of training and supplementation was observed on increasing TAC levels when compared to the DC group. Pearson’s correlation showed that the heart weight gain in the SDT group occurred only by decreasing the expression of the caspase-3 gene. Based on these results, probiotics combined with exercise training can be a strategy for improving the antioxidant defence system and preventing risk factors of diabetic cardiomyocytes, especially cell death and myocardial ischemia.
{"title":"Aerobic exercise training combined with probiotic supplement improves antioxidant defence of cardiomyocytes by regulating Nrf2 and caspase3 gene expression in type 2 diabetic rats","authors":"H. Maherinia, M. Peeri, M. azarbayjani, M. Delfan","doi":"10.3920/cep200089","DOIUrl":"https://doi.org/10.3920/cep200089","url":null,"abstract":"This study aimed to evaluate the effect of four weeks of aerobic exercise training combined with probiotic supplementation on mRNA levels of Nrf-2 and caspase-3 genes, superoxide dismutase (SOD), and serum total antioxidant capacity (TAC) in rats with type 2 diabetes. 40 male Wistar diabetic rats were divided into five groups: healthy placebo control group (NC), diabetic control group without supplement (DC), diabetic control group with supplement (SDC), diabetic aerobic training group without supplement (DT), and diabetic aerobic training group with probiotic supplement (SDT). Each training group performed training five days per week for four weeks and each session of training consisted of 30 min running on a treadmill with an intensity of 65-60% of maximum speed. Simultaneously, rats were fed probiotic supplements. Serum glucose, SOD, and TAC were analysed. The real-time PCR technique was used to determine the gene expression of Nrf-2 and caspase-3. Both aerobic exercise training and probiotic supplementation interactively reduced caspase 3 gene expression, increased Nrf-2 gene expression and enhanced TAC in the left ventricle of diabetic rats. Also, the reduction of caspase-3 mRNA in the left ventricle was more effective in the SDT group than in other diabetic groups. There was no interaction effect on SOD. However, a simultaneous effect of training and supplementation was observed on increasing TAC levels when compared to the DC group. Pearson’s correlation showed that the heart weight gain in the SDT group occurred only by decreasing the expression of the caspase-3 gene. Based on these results, probiotics combined with exercise training can be a strategy for improving the antioxidant defence system and preventing risk factors of diabetic cardiomyocytes, especially cell death and myocardial ischemia.","PeriodicalId":10709,"journal":{"name":"Comparative Exercise Physiology","volume":"25 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82076624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Menopause is an important period of life for women, all of whom experience this natural state. However, awareness of the bodily changes during this period is of great significance. Hence, not paying attention to the dietary, physical, and psychological criteria can reduce the quality of women’s lives. This study aimed to evaluate health-related quality of life (HRQoL), body composition, and physical fitness in postmenopausal women after Pilates exercises. Thirty postmenopausal Iranian women were randomly divided into Pilates (performed for 8 weeks) and control groups. The HRQoL Questionnaire (SF-12) was filled out, and a three-day record of food intake was also kept for dietary assessment. The diet of the women consisted of mean values of 1,923 Kcal daily energy, 16% protein, 72% carbohydrate, 12% fat, and 11.32 mg iron. Calcium, zinc, vitamin D, and vitamin E intake were respectively 73, 87.5, 81.7 and 83.53% of the recommended daily allowance. Pilates exercises had a significant effect on flexibility (P=0.002), endurance (P=0.001), muscle strength (P=0.001), body mass index (P=0.001), lean mass (P=0.003), body fat percentage (P=0.001), and quality of life (P=0.001). Therefore, Pilates is an appropriate training to increase body fitness and improve body composition, lean mass, and quality of life in postmenopausal women.
{"title":"Dietary assessment and effect of Pilates exercises on quality of life, body composition, and physical fitness in Iranian postmenopausal women","authors":"S. N. Boushehri, M. Farazmand, A. Zar","doi":"10.3920/cep210040","DOIUrl":"https://doi.org/10.3920/cep210040","url":null,"abstract":"Menopause is an important period of life for women, all of whom experience this natural state. However, awareness of the bodily changes during this period is of great significance. Hence, not paying attention to the dietary, physical, and psychological criteria can reduce the quality of women’s lives. This study aimed to evaluate health-related quality of life (HRQoL), body composition, and physical fitness in postmenopausal women after Pilates exercises. Thirty postmenopausal Iranian women were randomly divided into Pilates (performed for 8 weeks) and control groups. The HRQoL Questionnaire (SF-12) was filled out, and a three-day record of food intake was also kept for dietary assessment. The diet of the women consisted of mean values of 1,923 Kcal daily energy, 16% protein, 72% carbohydrate, 12% fat, and 11.32 mg iron. Calcium, zinc, vitamin D, and vitamin E intake were respectively 73, 87.5, 81.7 and 83.53% of the recommended daily allowance. Pilates exercises had a significant effect on flexibility (P=0.002), endurance (P=0.001), muscle strength (P=0.001), body mass index (P=0.001), lean mass (P=0.003), body fat percentage (P=0.001), and quality of life (P=0.001). Therefore, Pilates is an appropriate training to increase body fitness and improve body composition, lean mass, and quality of life in postmenopausal women.","PeriodicalId":10709,"journal":{"name":"Comparative Exercise Physiology","volume":"75 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80918990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Pramanik, S. Das, B. Kumar, S. Ganguly, M. Singh, K. Guleria, S. Shenoy, S.B. Singh
The present study aimed to investigate the effect of additional package of aerobic, anaerobic and strength training (AAS training), along with the conventional judo specific training, on autonomic nervous system balance, anaerobic capacity, exercise adaptation, phenotype of different blood mononuclear cells and cellular inflammatory signalling of university judo athletes. Thirty male judokas were randomly allocated to a control group/conventional judo specific training group (performing Uchi-komi, Nage komi, and Randori) or to an experimental group/conventional judo specific training + additional AAS training group. Physiological data including recovery ANS variables and anaerobic capacity were obtained by using wireless heart rate variability and anaerobic cycle ergometer, respectively, at two different time points (T1-pre, T3-post). Serum and primary mononuclear cells were prepared at three different time points (T1-pre, T2-acute, T3-post) and processed further as per the experimental requirement. For measuring the expression level of genes, and proteins biomarkers related to immune health, we have performed advanced qPCR array technique, flow cytometry, ELISA and zymosan-fluorescein assays. The additional training modality enhanced athletes’ anaerobic performance, parasympathetic functioning, and exercise adaptation. On the other hand, it decreased fatigue index, stress index, number of reactive immune cells, and intensity of inflammatory signalling. Overall, the present study, for the very first time, exhibited the positive effect of four weeks long additional AAS training on autonomic functioning, anaerobic capacity, and immune cell homeostasis of male judo athletes. This additional training package might also help the judo coaches to optimise training schedule for the competitive session.
{"title":"Supplemental aerobic, anaerobic and strength training positively affects autonomic functioning, anaerobic capacity, and immune cell homeostasis of male judo athletes","authors":"A. Pramanik, S. Das, B. Kumar, S. Ganguly, M. Singh, K. Guleria, S. Shenoy, S.B. Singh","doi":"10.3920/cep210018","DOIUrl":"https://doi.org/10.3920/cep210018","url":null,"abstract":"The present study aimed to investigate the effect of additional package of aerobic, anaerobic and strength training (AAS training), along with the conventional judo specific training, on autonomic nervous system balance, anaerobic capacity, exercise adaptation, phenotype of different blood mononuclear cells and cellular inflammatory signalling of university judo athletes. Thirty male judokas were randomly allocated to a control group/conventional judo specific training group (performing Uchi-komi, Nage komi, and Randori) or to an experimental group/conventional judo specific training + additional AAS training group. Physiological data including recovery ANS variables and anaerobic capacity were obtained by using wireless heart rate variability and anaerobic cycle ergometer, respectively, at two different time points (T1-pre, T3-post). Serum and primary mononuclear cells were prepared at three different time points (T1-pre, T2-acute, T3-post) and processed further as per the experimental requirement. For measuring the expression level of genes, and proteins biomarkers related to immune health, we have performed advanced qPCR array technique, flow cytometry, ELISA and zymosan-fluorescein assays. The additional training modality enhanced athletes’ anaerobic performance, parasympathetic functioning, and exercise adaptation. On the other hand, it decreased fatigue index, stress index, number of reactive immune cells, and intensity of inflammatory signalling. Overall, the present study, for the very first time, exhibited the positive effect of four weeks long additional AAS training on autonomic functioning, anaerobic capacity, and immune cell homeostasis of male judo athletes. This additional training package might also help the judo coaches to optimise training schedule for the competitive session.","PeriodicalId":10709,"journal":{"name":"Comparative Exercise Physiology","volume":"21 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76541353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. M. Z. Cabrera, W. R. Pineda, N.M. del Pilar Correa Valencia, M. P. A. Gutiérrez
Overweight and obesity in horses affect their athletic performance negatively, making it therefore necessary to develop training protocols that reduce their body fat without causing hoof injuries. The objective of the study was to describe the effect of the application of a swimming training program on metabolic and endocrine variables, in addition to evaluating the changes in subcutaneous fat thickness (SFT) in a group of overweight Colombian Paso Horses (CPHs). Six CPHs were subjected to a decreasing intensity swimming program for four months. The effect of this training on metabolic variables (i.e. aspartate aminotransferase, creatine kinase, triglycerides, cholesterol, glucose) and endocrines (cortisol and insulin) was studied every two months. Additionally, changes in the neck, lumbar, and gluteal SFTs were evaluated. The information was analysed using descriptive statistics, in addition to repeated measures analysis of variance for non-parametric data in the three training moments (P<0.1) and correlation analysis between the SFT and the metabolic and endocrine variables of interest. The swimming training program for CPHs tested in this study produced more evident redistribution of adipose tissue in the gluteal region (Initial SFT = 5.2±2.08 mm; Final SFT = 3.45±2.8 mm), conversion of body mass without weight modification, and use of energy sources such as triglycerides and increased sensitivity to insulin. A limitation of the study was that the horses were not selected according to age, nor were control animals used. In addition, the limited number of horses makes extrapolation of the results inappropriate. In conclusion, the swimming training program with decreasing intensity carried out over a four-month period modified body adipose tissue in CPHs, promoting the use of energy sources, such as triglycerides and increased insulin sensitivity.
{"title":"Body mass conversion and improved insulin response in Colombian Paso horses subjected to a swimming training program","authors":"A. M. Z. Cabrera, W. R. Pineda, N.M. del Pilar Correa Valencia, M. P. A. Gutiérrez","doi":"10.3920/cep210024","DOIUrl":"https://doi.org/10.3920/cep210024","url":null,"abstract":"Overweight and obesity in horses affect their athletic performance negatively, making it therefore necessary to develop training protocols that reduce their body fat without causing hoof injuries. The objective of the study was to describe the effect of the application of a swimming training program on metabolic and endocrine variables, in addition to evaluating the changes in subcutaneous fat thickness (SFT) in a group of overweight Colombian Paso Horses (CPHs). Six CPHs were subjected to a decreasing intensity swimming program for four months. The effect of this training on metabolic variables (i.e. aspartate aminotransferase, creatine kinase, triglycerides, cholesterol, glucose) and endocrines (cortisol and insulin) was studied every two months. Additionally, changes in the neck, lumbar, and gluteal SFTs were evaluated. The information was analysed using descriptive statistics, in addition to repeated measures analysis of variance for non-parametric data in the three training moments (P<0.1) and correlation analysis between the SFT and the metabolic and endocrine variables of interest. The swimming training program for CPHs tested in this study produced more evident redistribution of adipose tissue in the gluteal region (Initial SFT = 5.2±2.08 mm; Final SFT = 3.45±2.8 mm), conversion of body mass without weight modification, and use of energy sources such as triglycerides and increased sensitivity to insulin. A limitation of the study was that the horses were not selected according to age, nor were control animals used. In addition, the limited number of horses makes extrapolation of the results inappropriate. In conclusion, the swimming training program with decreasing intensity carried out over a four-month period modified body adipose tissue in CPHs, promoting the use of energy sources, such as triglycerides and increased insulin sensitivity.","PeriodicalId":10709,"journal":{"name":"Comparative Exercise Physiology","volume":"13 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73052706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Jansson, S. Ringmark, L. Johansson, L. Roepstorff
This study evaluated whether front and hind limb symmetry patterns observed from 1.5 through 3 years of age in Standardbred trotters in training affect racing activity at older age. The hypothesis tested was that asymmetries observed during this period are linked to reduced number of lifetime races and low earnings. Sixteen Standardbreds were subjected to a controlled training and dietary programme from the age of 1.5 years until December as 3-year-olds (P1) and then continued their career with other trainers. On 17 occasions during P1, locomotion asymmetry (vector sum) in front and hind limbs during trot in hand was recorded with a sensor-based system. By 10 years of age, data on lifetime number of races and earnings of the horses were obtained from the Swedish Trotting Association. Horses were divided in groups based on the number of lifetime races performed, i.e. more or less than the median of the cohort born the same year. Mean asymmetry levels did not differ between horses performing more or less lifetime races than the cohort median. However, horses that showed the poorest lifetime race activity showed elevated hind limb asymmetry in August at the age of 3 years, compared to horses with more races (group median: 6±2 mm (P=0.02)). There were no correlations between individual mean and peak asymmetries and lifetime earnings. It is concluded that locomotion symmetry observed during trot in hand at the age of 1.5-year-olds to December as 3-year-olds was not a simple and straight-forward predictor of future racing career. However, hind limb asymmetries of around 10 mm in the late season as 3-year-olds could be a warning of impaired future performance.
本研究评估了从1.5岁到3岁在训练中观察到的标准种马驹前肢和后肢对称模式是否会影响老年时的比赛活动。经过检验的假设是，在这一时期观察到的不对称与一生中种族数量减少和收入低有关。16只标准品种犬从1.5岁开始接受控制训练和饮食计划，直到3岁(P1) 12月，然后继续与其他驯兽师一起继续它们的职业生涯。在P1期间的17次中，使用基于传感器的系统记录了手部小跑时前肢和后肢的运动不对称性(矢量和)。到10岁时，从瑞典小跑协会获得了马的一生比赛次数和收入数据。马匹根据一生中参加比赛的次数进行分组，即比同一年出生的队列的中位数多或少。平均不对称水平在参加更多或更少比赛的马之间没有差异，而不是队列中位数。然而，与比赛次数较多的马相比，终生比赛活动最少的马在3岁时的8月份后肢不对称性增加(组中位数:6±2 mm (P=0.02))。个体平均和峰值不对称与终生收入之间没有相关性。结果表明，幼儿在1.5岁至3岁期间的手部小跑运动对称性并不能简单直接地预测其未来的赛车生涯。然而，在3岁的后期，后肢不对称约为10毫米，可能是未来表现受损的警告。
{"title":"Locomotion asymmetry in young Standardbred trotters in training and links to future racing career","authors":"A. Jansson, S. Ringmark, L. Johansson, L. Roepstorff","doi":"10.3920/cep210035","DOIUrl":"https://doi.org/10.3920/cep210035","url":null,"abstract":"This study evaluated whether front and hind limb symmetry patterns observed from 1.5 through 3 years of age in Standardbred trotters in training affect racing activity at older age. The hypothesis tested was that asymmetries observed during this period are linked to reduced number of lifetime races and low earnings. Sixteen Standardbreds were subjected to a controlled training and dietary programme from the age of 1.5 years until December as 3-year-olds (P1) and then continued their career with other trainers. On 17 occasions during P1, locomotion asymmetry (vector sum) in front and hind limbs during trot in hand was recorded with a sensor-based system. By 10 years of age, data on lifetime number of races and earnings of the horses were obtained from the Swedish Trotting Association. Horses were divided in groups based on the number of lifetime races performed, i.e. more or less than the median of the cohort born the same year. Mean asymmetry levels did not differ between horses performing more or less lifetime races than the cohort median. However, horses that showed the poorest lifetime race activity showed elevated hind limb asymmetry in August at the age of 3 years, compared to horses with more races (group median: 6±2 mm (P=0.02)). There were no correlations between individual mean and peak asymmetries and lifetime earnings. It is concluded that locomotion symmetry observed during trot in hand at the age of 1.5-year-olds to December as 3-year-olds was not a simple and straight-forward predictor of future racing career. However, hind limb asymmetries of around 10 mm in the late season as 3-year-olds could be a warning of impaired future performance.","PeriodicalId":10709,"journal":{"name":"Comparative Exercise Physiology","volume":"117 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83807166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Andarianto, P. S. Rejeki, Sakina, A. Pranoto, T.W. Aga Seputra, Sugiharto, M. Miftahussurur
Obesity is strongly associated with the degree of inflammation characterised by proinflammatory cytokines, such as tumour necrosis factor-α (TNF-α). Lifestyle modification with exercise is the right strategy because it can stimulate interleukin 6 (IL-6) secretion which acts as an anti-inflammatory. This study aimed to analyse the response of interval and continuous exercise to inflammatory markers in obese women. Twenty-four women participated in this study and were randomly divided into 3 groups: CONG (n=8, control group without any intervention): MCEG (n=8, continuous exercise group) and MIEG (n=8, interval exercise group). ELISA was used to measure the levels of IL-6 and TNF-α, pre-exercise and post-exercise. The data were analysed using the paired sample t-test. The mean levels of TNF-α, pre-exercise and post-exercise, were 19.35±2.73 vs 19.36±2.23 pg/ml (P=0.989) in CONG, 19.42±2.79 vs 16.63±0.82 pg/ml (P=0.017) in MCEG, and 19.46±3.08 vs 16.96±2.11 pg/ml (P=0.079) in MIEG. Mean levels of IL-6, pre-exercise and post-exercise, were 7.56±2.88 vs 7.66±4.12 pg/ml (P=0.957) for CONG, 7.68±3.41 vs 13.97±2.38 pg/ml (P=0.001) for MCEG, and 7.78±1.99 vs 13.66±3.55 pg/ml (P=0.001) for MIEG. We concluded that interval and continuous exercise decreased pro-inflammatory and increased anti-inflammatory cytokines.
肥胖与促炎细胞因子(如肿瘤坏死因子-α (TNF-α))的炎症程度密切相关。通过锻炼来改变生活方式是正确的策略，因为它可以刺激具有抗炎作用的白细胞介素6 (IL-6)的分泌。本研究旨在分析间歇和持续运动对肥胖女性炎症标志物的反应。24名女性参与本研究，随机分为3组:CONG组(n=8，不进行任何干预的对照组)、MCEG组(n=8，持续运动组)和MIEG组(n=8，间歇运动组)。采用ELISA法测定运动前、运动后小鼠IL-6、TNF-α水平。采用配对样本t检验对数据进行分析。运动前和运动后的TNF-α水平，CONG组19.35±2.73 vs 19.36±2.23 pg/ml (P=0.989)， MCEG组19.42±2.79 vs 16.63±0.82 pg/ml (P=0.017)， MIEG组19.46±3.08 vs 16.96±2.11 pg/ml (P=0.079)。运动前和运动后IL-6平均水平CONG组为7.56±2.88 vs 7.66±4.12 pg/ml (P=0.957)， MCEG组为7.68±3.41 vs 13.97±2.38 pg/ml (P=0.001)， MIEG组为7.78±1.99 vs 13.66±3.55 pg/ml (P=0.001)。我们的结论是，间歇和持续的运动可以减少促炎和增加抗炎细胞因子。
{"title":"Inflammatory markers in response to interval and continuous exercise in obese women","authors":"A. Andarianto, P. S. Rejeki, Sakina, A. Pranoto, T.W. Aga Seputra, Sugiharto, M. Miftahussurur","doi":"10.3920/cep210038","DOIUrl":"https://doi.org/10.3920/cep210038","url":null,"abstract":"Obesity is strongly associated with the degree of inflammation characterised by proinflammatory cytokines, such as tumour necrosis factor-α (TNF-α). Lifestyle modification with exercise is the right strategy because it can stimulate interleukin 6 (IL-6) secretion which acts as an anti-inflammatory. This study aimed to analyse the response of interval and continuous exercise to inflammatory markers in obese women. Twenty-four women participated in this study and were randomly divided into 3 groups: CONG (n=8, control group without any intervention): MCEG (n=8, continuous exercise group) and MIEG (n=8, interval exercise group). ELISA was used to measure the levels of IL-6 and TNF-α, pre-exercise and post-exercise. The data were analysed using the paired sample t-test. The mean levels of TNF-α, pre-exercise and post-exercise, were 19.35±2.73 vs 19.36±2.23 pg/ml (P=0.989) in CONG, 19.42±2.79 vs 16.63±0.82 pg/ml (P=0.017) in MCEG, and 19.46±3.08 vs 16.96±2.11 pg/ml (P=0.079) in MIEG. Mean levels of IL-6, pre-exercise and post-exercise, were 7.56±2.88 vs 7.66±4.12 pg/ml (P=0.957) for CONG, 7.68±3.41 vs 13.97±2.38 pg/ml (P=0.001) for MCEG, and 7.78±1.99 vs 13.66±3.55 pg/ml (P=0.001) for MIEG. We concluded that interval and continuous exercise decreased pro-inflammatory and increased anti-inflammatory cytokines.","PeriodicalId":10709,"journal":{"name":"Comparative Exercise Physiology","volume":"23 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2022-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85081641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Non-alcoholic fatty liver diseases (NAFLD) are particularly prevalent in the general Western adult population, with around one third of the population suffering from the disease. Evidence shows that NAFLD is associated with metabolic syndromes such as obesity, insulin resistance, and hypertension. Currently, the sole therapy for NAFLD involves exercise intervention. Studies showed that, with and without weight loss, exercise interventions produced a significant cutback in intrahepatic lipid content in humans, but better controlled studies that can investigate the cellular and molecular mechanisms are still lacking. In the current study we perform RNA sequencing analysis on liver samples from C57BL/6 mice submitted to aerobic exercise and diet interventions that are human-translatable and determine the genetic expression signature of exercise in the NAFLD onset. We show that aerobic exercise affects genes and pathways related to liver metabolism, muscle contraction and relaxation, immune response and inflammation, and development of liver cancer, counteracting non-alcoholic steatohepatitis and hepatocellular carcinoma development. While genes and pathways implicating immune response are activated by aerobic exercise in all interventions, the most effective intervention in terms of improvement of NASH is the combination of aerobic exercise with change of diet.
{"title":"Gene expression signature of exercise and change of diet on non-alcoholic fatty liver disease in mice","authors":"L. Melo, A. Hagar, J. Klaunig","doi":"10.3920/cep210033","DOIUrl":"https://doi.org/10.3920/cep210033","url":null,"abstract":"Non-alcoholic fatty liver diseases (NAFLD) are particularly prevalent in the general Western adult population, with around one third of the population suffering from the disease. Evidence shows that NAFLD is associated with metabolic syndromes such as obesity, insulin resistance, and hypertension. Currently, the sole therapy for NAFLD involves exercise intervention. Studies showed that, with and without weight loss, exercise interventions produced a significant cutback in intrahepatic lipid content in humans, but better controlled studies that can investigate the cellular and molecular mechanisms are still lacking. In the current study we perform RNA sequencing analysis on liver samples from C57BL/6 mice submitted to aerobic exercise and diet interventions that are human-translatable and determine the genetic expression signature of exercise in the NAFLD onset. We show that aerobic exercise affects genes and pathways related to liver metabolism, muscle contraction and relaxation, immune response and inflammation, and development of liver cancer, counteracting non-alcoholic steatohepatitis and hepatocellular carcinoma development. While genes and pathways implicating immune response are activated by aerobic exercise in all interventions, the most effective intervention in terms of improvement of NASH is the combination of aerobic exercise with change of diet.","PeriodicalId":10709,"journal":{"name":"Comparative Exercise Physiology","volume":"122 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87651947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hypertension is the most metastasizing non-communicable disease, which has affected more than 1.4 billion people, worldwide. Exercise is the core management strategy for hypertensive individuals. Extensive literature is available for each kind of exercise that is isometric hand grip training (IHGT), resistance training (RT), and aerobic training (AT). However, the comparison between these exercise regimens has not been done in a single trial. The trial was conducted on 126 subjects in Hisar, an urban area of Haryana (INDIA), from July 2017 to December 2018. Subjects were randomly assigned to four groups: control (n=33), IHGT (n=32), RT (n=31), and AT (n=30). Study variables were measured at baseline, 2nd week, 4th week, 6th week, and also after the 8th week of intervention. Experimental groups showed significant reduction in all the components of blood pressure in comparison to control group. The RT group showed maximum reduction in blood pressure in comparison to other regimens (systolic blood pressure: RT > IHGT > AT; diastolic blood pressure: RT > AT > IHGT). However, the difference between the groups is not statistically significant (P>0.05). The study findings reveal that different kind of exercise regimens are equally effective in lowering blood pressure among pre hypertensive and stage 1 hypertension adults.
高血压是最具转移性的非传染性疾病，影响了全球超过14亿人。运动是高血压患者的核心管理策略。关于握力训练(IHGT)、阻力训练(RT)和有氧训练(AT)的每一种训练都有大量的文献。然而，这些运动方案之间的比较并不是在单一试验中完成的。该试验于2017年7月至2018年12月在印度哈里亚纳邦城市地区希萨尔对126名受试者进行了试验。受试者被随机分为4组:对照组(n=33)、IHGT组(n=32)、RT组(n=31)和AT组(n=30)。在基线、第2周、第4周、第6周以及干预第8周后测量研究变量。与对照组相比，实验组的血压各项指标均有显著降低。与其他方案相比，RT组血压下降幅度最大(收缩压:RT > IHGT > AT;舒张压:RT > AT > IHGT)。但两组间差异无统计学意义(P>0.05)。研究结果表明，在高血压前期和1期高血压成人中，不同类型的运动方案对降低血压同样有效。
{"title":"Comparison of different types of exercise training on resting blood pressure in 30-45 years old adults: a randomised controlled trial","authors":"S. Punia, V. Singh, S. Joshi, M. Saini","doi":"10.3920/cep210012","DOIUrl":"https://doi.org/10.3920/cep210012","url":null,"abstract":"Hypertension is the most metastasizing non-communicable disease, which has affected more than 1.4 billion people, worldwide. Exercise is the core management strategy for hypertensive individuals. Extensive literature is available for each kind of exercise that is isometric hand grip training (IHGT), resistance training (RT), and aerobic training (AT). However, the comparison between these exercise regimens has not been done in a single trial. The trial was conducted on 126 subjects in Hisar, an urban area of Haryana (INDIA), from July 2017 to December 2018. Subjects were randomly assigned to four groups: control (n=33), IHGT (n=32), RT (n=31), and AT (n=30). Study variables were measured at baseline, 2nd week, 4th week, 6th week, and also after the 8th week of intervention. Experimental groups showed significant reduction in all the components of blood pressure in comparison to control group. The RT group showed maximum reduction in blood pressure in comparison to other regimens (systolic blood pressure: RT > IHGT > AT; diastolic blood pressure: RT > AT > IHGT). However, the difference between the groups is not statistically significant (P>0.05). The study findings reveal that different kind of exercise regimens are equally effective in lowering blood pressure among pre hypertensive and stage 1 hypertension adults.","PeriodicalId":10709,"journal":{"name":"Comparative Exercise Physiology","volume":"7 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89676163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The study investigated the association of orthostatic hypotension (OH) with functional position change and balance in older adults with hypertension. The presence of OH was assessed with intermittent (OH intermittent) and continuous blood pressure (OH continuous) monitoring. The change in functional position was tested with sitting to standing assessment, balance performance using activity specific balance confidence scale (ABC), and timed up and go test (TUG). Testing unilateral and bilateral standing with and without altered sensory inputs was tested using the Humac balance system. ABC, TUG, and standing up time showed no significant association with OH intermittent and OH continuous. A significant association was found between bilateral standing with eyes closed on foam surface for overall stability index and OH intermittent. Older people with hypertension may be routinely examined for OH and appropriate intervention strategies should be included for comprehensive care.
{"title":"Association of blood pressure and postural control in older adults with hypertension: an observational study","authors":"P. Sharma, S. Parveen, S. Masood, M. Noohu","doi":"10.3920/cep210016","DOIUrl":"https://doi.org/10.3920/cep210016","url":null,"abstract":"The study investigated the association of orthostatic hypotension (OH) with functional position change and balance in older adults with hypertension. The presence of OH was assessed with intermittent (OH intermittent) and continuous blood pressure (OH continuous) monitoring. The change in functional position was tested with sitting to standing assessment, balance performance using activity specific balance confidence scale (ABC), and timed up and go test (TUG). Testing unilateral and bilateral standing with and without altered sensory inputs was tested using the Humac balance system. ABC, TUG, and standing up time showed no significant association with OH intermittent and OH continuous. A significant association was found between bilateral standing with eyes closed on foam surface for overall stability index and OH intermittent. Older people with hypertension may be routinely examined for OH and appropriate intervention strategies should be included for comprehensive care.","PeriodicalId":10709,"journal":{"name":"Comparative Exercise Physiology","volume":"520 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2021-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77051779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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