Pub Date : 2023-09-14DOI: 10.3390/cosmetics10050128
Anna Grodecka, Olga Czerwińska-Ledwig, Adrianna Dzidek, Wiktoria Lis, Dorota Cwalińska, Weronika Kozioł, Aneta Teległów, Tomasz Pałka, Anna Piotrowska
Obesity is a disease of civilization. The COVID-19 pandemic has caused an increase in its incidence; therefore, there is an increasing emphasis on programs aimed at improving body composition, often through physical activity. Various modifications to training interventions are being introduced, including the modification of the thermo-climatic conditions of the training. However, to date, whether such a modification is safe for the skin has not been studied. The purpose of this study was to evaluate the effects of a series of workouts in a hypoxic chamber on skin characteristics such as elasticity, hydration, and transepidermal water loss (TEWL). Women who were overweight or obese were invited to participate in the project. The workouts took place in a hypoxic chamber where conditions were mimicked at 2500 m, three times a week for a period of four weeks, for 60 min each. Finally, the results from 11 women in the study group and 9 in the control group were included in the analysis. Body composition analysis was performed, and venous blood was drawn (morphology and lipidogram). No statistically significant changes in skin firmness or the amount of TEWL were observed in the subjects. An increase in skin hydration on the hand was observed only after the first workout (p = 0.046), while skin hydration on the mandible did not change. A significant reduction in body weight (p = 0.042), BMI (p = 0.045), and TBW (p = 0.017) was indicated in the study group. The control group showed an increase in BMI (p = 0.045) and VFA (p = 0.042). There was no correlation between measured skin characteristics and body composition indices or the results of blood indices. A correlation was observed between TEWL and lipidogram results. Training under hypoxic conditions does not affect skin features in overweight and obese women. Even a significant reduction in TBW did not result in a decrease in hydration. It was also shown that the proper barrier function of the skin is closely dependent on the serum lipid profile.
{"title":"Effect of the Hypoxic Chamber Training Series on Skin Characteristics of Overweight and Obese Women","authors":"Anna Grodecka, Olga Czerwińska-Ledwig, Adrianna Dzidek, Wiktoria Lis, Dorota Cwalińska, Weronika Kozioł, Aneta Teległów, Tomasz Pałka, Anna Piotrowska","doi":"10.3390/cosmetics10050128","DOIUrl":"https://doi.org/10.3390/cosmetics10050128","url":null,"abstract":"Obesity is a disease of civilization. The COVID-19 pandemic has caused an increase in its incidence; therefore, there is an increasing emphasis on programs aimed at improving body composition, often through physical activity. Various modifications to training interventions are being introduced, including the modification of the thermo-climatic conditions of the training. However, to date, whether such a modification is safe for the skin has not been studied. The purpose of this study was to evaluate the effects of a series of workouts in a hypoxic chamber on skin characteristics such as elasticity, hydration, and transepidermal water loss (TEWL). Women who were overweight or obese were invited to participate in the project. The workouts took place in a hypoxic chamber where conditions were mimicked at 2500 m, three times a week for a period of four weeks, for 60 min each. Finally, the results from 11 women in the study group and 9 in the control group were included in the analysis. Body composition analysis was performed, and venous blood was drawn (morphology and lipidogram). No statistically significant changes in skin firmness or the amount of TEWL were observed in the subjects. An increase in skin hydration on the hand was observed only after the first workout (p = 0.046), while skin hydration on the mandible did not change. A significant reduction in body weight (p = 0.042), BMI (p = 0.045), and TBW (p = 0.017) was indicated in the study group. The control group showed an increase in BMI (p = 0.045) and VFA (p = 0.042). There was no correlation between measured skin characteristics and body composition indices or the results of blood indices. A correlation was observed between TEWL and lipidogram results. Training under hypoxic conditions does not affect skin features in overweight and obese women. Even a significant reduction in TBW did not result in a decrease in hydration. It was also shown that the proper barrier function of the skin is closely dependent on the serum lipid profile.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":"70 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134913700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-08DOI: 10.3390/cosmetics10050126
Simone Amato, S. Nisticò, Giovanni Pellacani, Stefania Guida, Anthony Rossi, Caterina Longo, E. Berardesca, G. Cannarozzo
Auricular keloids pose significant aesthetic and functional challenges, and traditional treatments often fall short in addressing these issues. Our study presents an innovative combined approach of ablative CO2 and dye laser therapy for improved keloid management. This treatment protocol was applied to 15 patients with auricular keloids after an initial multispectral analysis to assess keloid composition. The laser sequence was tailored per patient based on this analysis. Evaluations using the Vancouver Scar Scale and Patient and Observer Scar Assessment Scale were carried out at baseline and at 3-week intervals post-treatment. The results showed a significant reduction in these scores at the final follow-up (p < 0.05), suggesting improvements in keloid color, texture, and pliability, with minimal adverse events. Additionally, no recurrence of keloids was observed. Our findings indicate that this novel methodology of multispectral analysis followed by tailored laser therapy may offer a safe and effective solution for auricular keloids, promising enhanced keloid treatment and prevention of recurrence. However, further investigations, including randomized controlled trials, are needed to confirm and optimize this treatment protocol.
{"title":"Sequential and Combined Efficacious Management of Auricular Keloid: A Novel Treatment Protocol Employing Ablative CO2 and Dye Laser Therapy—An Advanced Single-Center Clinical Investigation","authors":"Simone Amato, S. Nisticò, Giovanni Pellacani, Stefania Guida, Anthony Rossi, Caterina Longo, E. Berardesca, G. Cannarozzo","doi":"10.3390/cosmetics10050126","DOIUrl":"https://doi.org/10.3390/cosmetics10050126","url":null,"abstract":"Auricular keloids pose significant aesthetic and functional challenges, and traditional treatments often fall short in addressing these issues. Our study presents an innovative combined approach of ablative CO2 and dye laser therapy for improved keloid management. This treatment protocol was applied to 15 patients with auricular keloids after an initial multispectral analysis to assess keloid composition. The laser sequence was tailored per patient based on this analysis. Evaluations using the Vancouver Scar Scale and Patient and Observer Scar Assessment Scale were carried out at baseline and at 3-week intervals post-treatment. The results showed a significant reduction in these scores at the final follow-up (p < 0.05), suggesting improvements in keloid color, texture, and pliability, with minimal adverse events. Additionally, no recurrence of keloids was observed. Our findings indicate that this novel methodology of multispectral analysis followed by tailored laser therapy may offer a safe and effective solution for auricular keloids, promising enhanced keloid treatment and prevention of recurrence. However, further investigations, including randomized controlled trials, are needed to confirm and optimize this treatment protocol.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48575139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-07DOI: 10.3390/cosmetics10050125
Kasemsan Atisakul, N. Saewan
Oral malodor, often known as halitosis, is an irritating breath odor that originates in the mouth and can cause significant psychological and social distress. Chlorhexidine, a powerful antimicrobial agent effective against bacteria and fungi, has become the standard treatment for halitosis. However, it has drawbacks including altered taste perception, dry mouth, and more noticeable dental staining. The use of natural essential oils to avoid these unwanted effects has proven to be an attractive strategy. This study aims to evaluate the potential of four essential oils consisting of Ma-kwean fruit (Zanthoxylum limonella, MK), clove bud (Syzygium aromaticum, CV), star anise fruit (Illicium verum, SA) and cinnamon bark (Cinnamomum aromaticum, CM) for the purpose of combating bad breath by assessing their antibacterial efficacy against halitosis-associated bacteria (Streptococcus mutans and Solobacterium moorei). The hydro-distillation process was used to prepare the essential oils, which were obtained as yellowish to colorless liquids with yields of 6.58 ± 0.81, 12.21 ± 2.98, 4.29 ± 0.15 and 1.26 ± 0.09% for MK, CV, SA and CM, respectively. The terpenoid compounds terpinene-4-ol (47.04%), limonene (17.19%), sabinene (13.27%) and alpha-terpineol (6.05%) were found as the main components in MK essential oil, while phenylpropanoids were identified as the primary components of other essential oils, namely trans-cinnamaldehyde (83.60%), eugenol (83.59%) and anethol (90.58%) were identified as the primary components of CM, CV and SA essential oils, respectively. For the antibacterial properties, the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) values were investigated. CM essential oil exhibited the greatest capacity to inhibit growth and eradicate S. mutans, with MIC and MBC values of 0.039%, followed by CV (MIC of 0.078% and MBC of 0.156%) and MK (MIC and MBC of 0.156%), whereas the MIC of SA was 1.250% without eradication. Both CM and CV essential oils demonstrated exceptional efficacy against S. moorei, with MIC and MBC values of 0.019% and 0.033%, respectively. Furthermore, the inhibition of S. moorei biofilm formation was investigated and we discovered that the lowest effective concentration necessary to eliminate the S. moorei biofilm was one quarter of the MIC for MK, CM and CV, while that for SA essential oil was half of the MIC. These encouraging results suggest that the incorporation of MK, CM and CV essential oils into oral care products could potentially enhance their efficacy in halitosis treatment.
{"title":"The Antibacterial Potential of Essential Oils of Oral Care Thai Herbs against Streptococcus mutans and Solobacterium moorei—In Vitro Approach","authors":"Kasemsan Atisakul, N. Saewan","doi":"10.3390/cosmetics10050125","DOIUrl":"https://doi.org/10.3390/cosmetics10050125","url":null,"abstract":"Oral malodor, often known as halitosis, is an irritating breath odor that originates in the mouth and can cause significant psychological and social distress. Chlorhexidine, a powerful antimicrobial agent effective against bacteria and fungi, has become the standard treatment for halitosis. However, it has drawbacks including altered taste perception, dry mouth, and more noticeable dental staining. The use of natural essential oils to avoid these unwanted effects has proven to be an attractive strategy. This study aims to evaluate the potential of four essential oils consisting of Ma-kwean fruit (Zanthoxylum limonella, MK), clove bud (Syzygium aromaticum, CV), star anise fruit (Illicium verum, SA) and cinnamon bark (Cinnamomum aromaticum, CM) for the purpose of combating bad breath by assessing their antibacterial efficacy against halitosis-associated bacteria (Streptococcus mutans and Solobacterium moorei). The hydro-distillation process was used to prepare the essential oils, which were obtained as yellowish to colorless liquids with yields of 6.58 ± 0.81, 12.21 ± 2.98, 4.29 ± 0.15 and 1.26 ± 0.09% for MK, CV, SA and CM, respectively. The terpenoid compounds terpinene-4-ol (47.04%), limonene (17.19%), sabinene (13.27%) and alpha-terpineol (6.05%) were found as the main components in MK essential oil, while phenylpropanoids were identified as the primary components of other essential oils, namely trans-cinnamaldehyde (83.60%), eugenol (83.59%) and anethol (90.58%) were identified as the primary components of CM, CV and SA essential oils, respectively. For the antibacterial properties, the minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) values were investigated. CM essential oil exhibited the greatest capacity to inhibit growth and eradicate S. mutans, with MIC and MBC values of 0.039%, followed by CV (MIC of 0.078% and MBC of 0.156%) and MK (MIC and MBC of 0.156%), whereas the MIC of SA was 1.250% without eradication. Both CM and CV essential oils demonstrated exceptional efficacy against S. moorei, with MIC and MBC values of 0.019% and 0.033%, respectively. Furthermore, the inhibition of S. moorei biofilm formation was investigated and we discovered that the lowest effective concentration necessary to eliminate the S. moorei biofilm was one quarter of the MIC for MK, CM and CV, while that for SA essential oil was half of the MIC. These encouraging results suggest that the incorporation of MK, CM and CV essential oils into oral care products could potentially enhance their efficacy in halitosis treatment.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44941849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-06DOI: 10.3390/cosmetics10050124
Sophia Letsiou, Maria Trapali, Despina Vougiouklaki, Aliki Tsakni, Dionysis Antonopoulos, Dimitra P. Houhoula
Skin aging mainly occurs due to intrinsic and extrinsic factors. Extrinsic aging is a consequence of exposure to ultraviolet radiation. Meanwhile, natural products exhibit protective properties against skin aging as well as photoaging. In this context, the research on natural anti-aging agents is greatly advanced, and in recent years, numerous plant-based products have been investigated. The aim of this study was to assess the antioxidant profile of Origanum dictamnus L. extract as well as its antiaging effects on 2D cultures of fibroblasts and keratinocytes under UVA irradiation to unravel the potential role of Origanum dictamnus L. in cosmetology. In an attempt to explore the antioxidant profile of the extract, we employed well-established enzymatic assays (DPPH, FRAP, ABTS, and TPC) and a phytochemical screening by LC/MS. According to our findings, the Origanum dictamnus L. extract possesses high scavenging activity (DPPH, ABTS), high phenolic content (TPC), and high Fe(III)-reduction activity (FRAP). Moreover, the LC/MS analysis revealed that the extract was rich in flavonoids, holding a high content of curcumin, kampferol, silymarin, cyanidin-3-glucoside, deosmin, rutin, and quercetin. To gain insight into the bioactivity of Origanum dictamnus L. extract in cell aging, the expression of various genes that are implicated in the skin aging process in keratinocytes and fibroblasts was studied. The gene expression analysis revealed that the extract increases cell proliferation in the cells exposed to UVA irradiation and concomitantly modulates the expression of genes related to the aging process in keratinocytes (KLK7, OCLN, GBA1) and fibroblasts (SIRT2, FOXO3, COL3A1) under the same conditions.
{"title":"Antioxidant Profile of Origanum dictamnus L. Exhibits Antiaging Properties against UVA Irradiation","authors":"Sophia Letsiou, Maria Trapali, Despina Vougiouklaki, Aliki Tsakni, Dionysis Antonopoulos, Dimitra P. Houhoula","doi":"10.3390/cosmetics10050124","DOIUrl":"https://doi.org/10.3390/cosmetics10050124","url":null,"abstract":"Skin aging mainly occurs due to intrinsic and extrinsic factors. Extrinsic aging is a consequence of exposure to ultraviolet radiation. Meanwhile, natural products exhibit protective properties against skin aging as well as photoaging. In this context, the research on natural anti-aging agents is greatly advanced, and in recent years, numerous plant-based products have been investigated. The aim of this study was to assess the antioxidant profile of Origanum dictamnus L. extract as well as its antiaging effects on 2D cultures of fibroblasts and keratinocytes under UVA irradiation to unravel the potential role of Origanum dictamnus L. in cosmetology. In an attempt to explore the antioxidant profile of the extract, we employed well-established enzymatic assays (DPPH, FRAP, ABTS, and TPC) and a phytochemical screening by LC/MS. According to our findings, the Origanum dictamnus L. extract possesses high scavenging activity (DPPH, ABTS), high phenolic content (TPC), and high Fe(III)-reduction activity (FRAP). Moreover, the LC/MS analysis revealed that the extract was rich in flavonoids, holding a high content of curcumin, kampferol, silymarin, cyanidin-3-glucoside, deosmin, rutin, and quercetin. To gain insight into the bioactivity of Origanum dictamnus L. extract in cell aging, the expression of various genes that are implicated in the skin aging process in keratinocytes and fibroblasts was studied. The gene expression analysis revealed that the extract increases cell proliferation in the cells exposed to UVA irradiation and concomitantly modulates the expression of genes related to the aging process in keratinocytes (KLK7, OCLN, GBA1) and fibroblasts (SIRT2, FOXO3, COL3A1) under the same conditions.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43639453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-05DOI: 10.3390/cosmetics10050123
Laura Aguilar, Jonathan Hernández, L. López-Giraldo, Ronald Mercado
Most waxes used as cosmetic ingredients are derived from the petrochemical industry. A modern alternative to this complex synthesis approach is the hydrotreatment of palm oil; thus, the aim of this study is to evaluate the effect of incorporating a biowax derived from hydroprocessing of crude palm oil as a new natural cosmetic ingredient in facial cream and BB cream. Therefore, two water in oil (W/O) emulsions, one including pigments, with five different weight percentages were developed and subjected to further sensory evaluation by a trained panel to estimate the level of acceptance. Moreover, resistance to centrifugation, pH, spreadability, phase separation, viscosity and storage modulus were the parameters evaluated in a preliminary stability study using thermal stress. Sensory analysis showed that the highest level of acceptance was obtained between 3% and 9 wt% biowax. For both prototypes, increasing biowax percentage led to a greater effect on stickiness, the viscosity increased, and extensibility decreased. The formulations were able to maintain their pH. The best stability for BB cream was observed at 9%, since the changes in the properties were slight. For facial cream, the emulsion was more stable at intermediate biowax content. It was observed that biowax exhibits favorable characteristics as an emollient or thickening agent. Finally, the formulations with the best stability and sensory characteristics were obtained at 9 wt% biowax.
{"title":"Effect of Incorporating a Biowax Derived from Hydroprocessing of Crude Palm Oil in a Facial Cream and a Blemish Balm Cream","authors":"Laura Aguilar, Jonathan Hernández, L. López-Giraldo, Ronald Mercado","doi":"10.3390/cosmetics10050123","DOIUrl":"https://doi.org/10.3390/cosmetics10050123","url":null,"abstract":"Most waxes used as cosmetic ingredients are derived from the petrochemical industry. A modern alternative to this complex synthesis approach is the hydrotreatment of palm oil; thus, the aim of this study is to evaluate the effect of incorporating a biowax derived from hydroprocessing of crude palm oil as a new natural cosmetic ingredient in facial cream and BB cream. Therefore, two water in oil (W/O) emulsions, one including pigments, with five different weight percentages were developed and subjected to further sensory evaluation by a trained panel to estimate the level of acceptance. Moreover, resistance to centrifugation, pH, spreadability, phase separation, viscosity and storage modulus were the parameters evaluated in a preliminary stability study using thermal stress. Sensory analysis showed that the highest level of acceptance was obtained between 3% and 9 wt% biowax. For both prototypes, increasing biowax percentage led to a greater effect on stickiness, the viscosity increased, and extensibility decreased. The formulations were able to maintain their pH. The best stability for BB cream was observed at 9%, since the changes in the properties were slight. For facial cream, the emulsion was more stable at intermediate biowax content. It was observed that biowax exhibits favorable characteristics as an emollient or thickening agent. Finally, the formulations with the best stability and sensory characteristics were obtained at 9 wt% biowax.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46889333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-31DOI: 10.3390/cosmetics10050122
K. Seretis, Konstantina Papaioannou
Laser-assisted drug delivery (LADD) has gained prominence as a promising technique with the potential to enhance topical drug skin penetration and absorption. However, the effectiveness of various laser-assisted facial procedures remains unclear. This systematic review aimed to explore and summarize the evidence regarding the indications, clinical outcomes, and adverse effects of LADD performed on the face. Based on a predetermined protocol, an electronic search in MEDLINE, Scopus, the Cochrane Library, and CENTRAL electronic databases was conducted. Eligible studies comprised prospective controlled trials that explored the utility of laser-assisted techniques for topical medication facial application and reported on efficacy and/or safety. Secondary outcomes encompassed patient satisfaction. This review included 12 prospective controlled studies involving a total of 271 participants. LADD, through various laser types, topical medications, clinical protocols, and follow-up assessments, showed enhanced melasma, facial rejuvenation, scar, and periprocedural laser outcomes without increased risk of adverse effects. This review provides evidence that LADD is an effective and safe adjunct for various facial procedures. It also highlights the necessity for further high-quality studies with larger sample sizes, standardized treatment protocols, and evaluation of long-term outcomes and adverse effects in order to elucidate the potential of laser-assisted drug delivery.
{"title":"Laser-Assisted Drug Delivery on the Face: A Systematic Review of Indications and Outcomes","authors":"K. Seretis, Konstantina Papaioannou","doi":"10.3390/cosmetics10050122","DOIUrl":"https://doi.org/10.3390/cosmetics10050122","url":null,"abstract":"Laser-assisted drug delivery (LADD) has gained prominence as a promising technique with the potential to enhance topical drug skin penetration and absorption. However, the effectiveness of various laser-assisted facial procedures remains unclear. This systematic review aimed to explore and summarize the evidence regarding the indications, clinical outcomes, and adverse effects of LADD performed on the face. Based on a predetermined protocol, an electronic search in MEDLINE, Scopus, the Cochrane Library, and CENTRAL electronic databases was conducted. Eligible studies comprised prospective controlled trials that explored the utility of laser-assisted techniques for topical medication facial application and reported on efficacy and/or safety. Secondary outcomes encompassed patient satisfaction. This review included 12 prospective controlled studies involving a total of 271 participants. LADD, through various laser types, topical medications, clinical protocols, and follow-up assessments, showed enhanced melasma, facial rejuvenation, scar, and periprocedural laser outcomes without increased risk of adverse effects. This review provides evidence that LADD is an effective and safe adjunct for various facial procedures. It also highlights the necessity for further high-quality studies with larger sample sizes, standardized treatment protocols, and evaluation of long-term outcomes and adverse effects in order to elucidate the potential of laser-assisted drug delivery.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43363329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-29DOI: 10.3390/cosmetics10050121
Kanyanat Theeraraksakul, Kittitat Jaengwang, K. Choowongkomon, Lueacha Tabtimmai
Phallus indusiatus, or bamboo mushroom, has been reported for its nutraceutical properties, while its cosmeceutical properties remain unclear. In this study, we conducted extractions of whole, fresh P. indusiatus using both aqueous and ethanolic methods. Among the extracts, ultrasonic-assisted extraction method with DI showed the highest antioxidant activity compared to the others. For cosmeceutical assessment, we evaluated the extracts’ inhibitory effects against ECM-degrading enzymes and found that they exhibited a modest inhibitory effect of approximately 50%. Remarkably, ultrasonic-assisted extraction with DI demonstrated promising cosmeceutical properties. Additionally, pressure-assisted extraction with DI showed a potentially protective effect against H2O2-induced DNA damage. To investigate the anti-melanogenic effect on MNT-1 cells, we treated them with the extracts and observed a significant decrease in cellular tyrosinase activity under α-MSH stimulation. This resulted in a relative reduction in melanin content. Notably, autoclaving extraction exhibited a significantly greater anti-melanogenic effect than the other extracts at the lowest concentration tested. Furthermore, the extracts demonstrated a reduction in NO production under LPS-induced inflammation. Hot water extraction with DI and ethanol exhibited a stronger anti-inflammatory effect compared to diclofenac, without any cytotoxicity. These findings highlight the hidden cosmeceutical properties of P. indusiatus and suggest its potential use as a bioactive ingredient in cosmetic formulations.
{"title":"Exploring the Biological Functions and Anti-Melanogenesis of Phallus indusiatus for Mushroom-Based Cosmetic Applications","authors":"Kanyanat Theeraraksakul, Kittitat Jaengwang, K. Choowongkomon, Lueacha Tabtimmai","doi":"10.3390/cosmetics10050121","DOIUrl":"https://doi.org/10.3390/cosmetics10050121","url":null,"abstract":"Phallus indusiatus, or bamboo mushroom, has been reported for its nutraceutical properties, while its cosmeceutical properties remain unclear. In this study, we conducted extractions of whole, fresh P. indusiatus using both aqueous and ethanolic methods. Among the extracts, ultrasonic-assisted extraction method with DI showed the highest antioxidant activity compared to the others. For cosmeceutical assessment, we evaluated the extracts’ inhibitory effects against ECM-degrading enzymes and found that they exhibited a modest inhibitory effect of approximately 50%. Remarkably, ultrasonic-assisted extraction with DI demonstrated promising cosmeceutical properties. Additionally, pressure-assisted extraction with DI showed a potentially protective effect against H2O2-induced DNA damage. To investigate the anti-melanogenic effect on MNT-1 cells, we treated them with the extracts and observed a significant decrease in cellular tyrosinase activity under α-MSH stimulation. This resulted in a relative reduction in melanin content. Notably, autoclaving extraction exhibited a significantly greater anti-melanogenic effect than the other extracts at the lowest concentration tested. Furthermore, the extracts demonstrated a reduction in NO production under LPS-induced inflammation. Hot water extraction with DI and ethanol exhibited a stronger anti-inflammatory effect compared to diclofenac, without any cytotoxicity. These findings highlight the hidden cosmeceutical properties of P. indusiatus and suggest its potential use as a bioactive ingredient in cosmetic formulations.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2023-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44775475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-28DOI: 10.3390/cosmetics10050120
F. Biskanaki, Paraskevi Kalofiri, N. Tertipi, E. Sfyri, Eleni Andreou, V. Kefala, E. Rallis
Food technology, health, nutrition, dermatology, and aesthetics have focused on colorless carotenoids. Carotenoids are readily bioavailable and have demonstrated various health-promoting actions. This article reviews the recent literature concerning carotenoids with the aim to systematize the scattered knowledge on carotenoids and aesthetics. The applications of carotenoids in health-promoting and nutrient products and their potential health effects are discussed. The carotenoids, particularly phytoene and phytofluene, have the unique ability to absorb ultraviolet radiation. Their distinct structures and properties, oxidation sensitivity, stiffness, aggregation tendency, and even fluorescence in the case of phytofluene, contribute to their potential benefits. A diet rich in carotenoid-containing products can positively impact skin health, overall well-being, and the prevention of various diseases. Future studies should focus on generating more data about phytoene and phytofluene levels in the skin to accurately assess skin carotenoid status. This expanding area of research holds promise for the development of novel applications in the fields of health and cosmetics.
{"title":"Carotenoids and Dermoaesthetic Benefits: Public Health Implications","authors":"F. Biskanaki, Paraskevi Kalofiri, N. Tertipi, E. Sfyri, Eleni Andreou, V. Kefala, E. Rallis","doi":"10.3390/cosmetics10050120","DOIUrl":"https://doi.org/10.3390/cosmetics10050120","url":null,"abstract":"Food technology, health, nutrition, dermatology, and aesthetics have focused on colorless carotenoids. Carotenoids are readily bioavailable and have demonstrated various health-promoting actions. This article reviews the recent literature concerning carotenoids with the aim to systematize the scattered knowledge on carotenoids and aesthetics. The applications of carotenoids in health-promoting and nutrient products and their potential health effects are discussed. The carotenoids, particularly phytoene and phytofluene, have the unique ability to absorb ultraviolet radiation. Their distinct structures and properties, oxidation sensitivity, stiffness, aggregation tendency, and even fluorescence in the case of phytofluene, contribute to their potential benefits. A diet rich in carotenoid-containing products can positively impact skin health, overall well-being, and the prevention of various diseases. Future studies should focus on generating more data about phytoene and phytofluene levels in the skin to accurately assess skin carotenoid status. This expanding area of research holds promise for the development of novel applications in the fields of health and cosmetics.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":"1 1","pages":""},"PeriodicalIF":3.3,"publicationDate":"2023-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41373379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-23DOI: 10.3390/cosmetics10050118
A. Manea, D. Perju, A. Tamás
This paper reviews research on some cosmetic creams considered “distributed parameters systems” and on the experimental-computational mathematical models that have been determined for them. The determined models characterize the cosmetic creams in all stages of the manufacturing process, starting with the development of recipes, the description of raw materials, manufacturing technologies, and the determination of the physico-chemical and microbiological indicators that most strongly influence their quality. This approach suggests the possibility of performing optimization operations, specifically sensitivity analyses, which may lead to the identification of best quality indicators and to the amelioration of negative effects related to disturbance sizes (temperature, pressure, humidity etc.). Five emulsions with different compositions, prepared in vitro according to our own recipes, using raw materials and preparation methods approved for cosmetic products, were studied. Through specific physico-chemical and microbiological analyses, we obtained databases that were processed computationally. The resulting mathematical models, in the form of both graphs and equations, led to important conclusions regarding obtaining high quality in the studied creams and to the confirmation of the usefulness of applying the principles of Systems Theory to the study of cosmetic products.
{"title":"The Method of Studying Cosmetic Creams Based on the Principles of Systems Theory and Mathematical Modeling Techniques","authors":"A. Manea, D. Perju, A. Tamás","doi":"10.3390/cosmetics10050118","DOIUrl":"https://doi.org/10.3390/cosmetics10050118","url":null,"abstract":"This paper reviews research on some cosmetic creams considered “distributed parameters systems” and on the experimental-computational mathematical models that have been determined for them. The determined models characterize the cosmetic creams in all stages of the manufacturing process, starting with the development of recipes, the description of raw materials, manufacturing technologies, and the determination of the physico-chemical and microbiological indicators that most strongly influence their quality. This approach suggests the possibility of performing optimization operations, specifically sensitivity analyses, which may lead to the identification of best quality indicators and to the amelioration of negative effects related to disturbance sizes (temperature, pressure, humidity etc.). Five emulsions with different compositions, prepared in vitro according to our own recipes, using raw materials and preparation methods approved for cosmetic products, were studied. Through specific physico-chemical and microbiological analyses, we obtained databases that were processed computationally. The resulting mathematical models, in the form of both graphs and equations, led to important conclusions regarding obtaining high quality in the studied creams and to the confirmation of the usefulness of applying the principles of Systems Theory to the study of cosmetic products.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46567235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-23DOI: 10.3390/cosmetics10050119
Ante Sučić, A. Š. Perišin, Tomislav Žuvela, D. Leskur, D. Rušić, D. Modun, J. Bukić
Botulinum toxin use has become the most commonly performed aesthetic procedure among individuals of all age groups, encompassing both women and men. Randomized controlled trials (RCTs) provide the highest level of evidence and quality reporting of their abstracts plays a significant role for health professionals, influencing their decision-making in patient management. Therefore, our study aimed to assess the reporting quality of published RCT abstracts for botulinum toxin aesthetic use in the head area. The CONSORT-A checklist with 17 items was used to assess the quality of reporting. All available RCT abstracts (N = 191) found by searching the Medline database that were published up until June 2023 were included in this study. The average reporting rate was 52.9%. General items were inadequately reported (30.9%), with few abstracts describing the trial design. The methods section was better reported (62.0%), with interventions, objectives, and outcomes properly reported in over 97.5% abstracts. The results section (56.9%) demonstrated good reporting of randomized participant numbers but limited reporting of primary outcomes and harms. None of the abstracts reported funding sources or randomization information. To enhance the transparency and reliability of RCT results, abstracts should adhere more rigorously to the CONSORT-A guidelines. Improved reporting in abstracts can facilitate evidence-based decision-making in everyday practice of medical professionals in the field of aesthetic medicine.
{"title":"Reporting Quality of Randomized Controlled Trial Abstracts on Aesthetic Use of Botulinum Toxin: How Much Do Abstracts Actually Tell Us?","authors":"Ante Sučić, A. Š. Perišin, Tomislav Žuvela, D. Leskur, D. Rušić, D. Modun, J. Bukić","doi":"10.3390/cosmetics10050119","DOIUrl":"https://doi.org/10.3390/cosmetics10050119","url":null,"abstract":"Botulinum toxin use has become the most commonly performed aesthetic procedure among individuals of all age groups, encompassing both women and men. Randomized controlled trials (RCTs) provide the highest level of evidence and quality reporting of their abstracts plays a significant role for health professionals, influencing their decision-making in patient management. Therefore, our study aimed to assess the reporting quality of published RCT abstracts for botulinum toxin aesthetic use in the head area. The CONSORT-A checklist with 17 items was used to assess the quality of reporting. All available RCT abstracts (N = 191) found by searching the Medline database that were published up until June 2023 were included in this study. The average reporting rate was 52.9%. General items were inadequately reported (30.9%), with few abstracts describing the trial design. The methods section was better reported (62.0%), with interventions, objectives, and outcomes properly reported in over 97.5% abstracts. The results section (56.9%) demonstrated good reporting of randomized participant numbers but limited reporting of primary outcomes and harms. None of the abstracts reported funding sources or randomization information. To enhance the transparency and reliability of RCT results, abstracts should adhere more rigorously to the CONSORT-A guidelines. Improved reporting in abstracts can facilitate evidence-based decision-making in everyday practice of medical professionals in the field of aesthetic medicine.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":" ","pages":""},"PeriodicalIF":3.3,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43678915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：