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Bridging the gap: How SiX supports U.S. state legislators in transforming research into policy 弥合差距:SiX如何支持美国州议员将研究转化为政策。
IF 2.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-27 DOI: 10.1016/j.contraception.2025.111249
Melissa Madera , Rosann Mariappuram , Candi Mundon King , Charlane Oliver , Julie von Haefen , Fran Linkin
The right to contraception has been protected under the U.S. Constitution since the U.S. Supreme Court decisions in Griswold v. Connecticut (1965) and Eisenstadt v. Baird (1972). However, even with these constitutional protections in place, there have been increased direct attacks from conservative state legislators on contraception using state legislation. But state legislators supportive of reproductive health, rights, and justice continue to push forward on proactive progressive legislation and policies that safeguard contraception. The State Innovation Exchange’s (SiX) Reproductive Rights team launched the Reproductive Freedom Leadership Council (RFLC) in 2018 to support state legislators who champion progressive policies focused on reproductive health, rights, and justice with, among other resources, the tracking and translation of scientific research on family planning and sexual, reproductive, and maternal health, and connecting them with the researchers who produce those data. In this commentary, we provide an overview of how state legislators champion progressive contraceptive policies in their states and offer observations on the role of research from state legislators within the RFLC network. Our objective for this commentary is to share best practices and guidance from legislators themselves about how researchers can make their research more accessible to legislators as they push back against conservative attacks on bodily autonomy.
自1965年格里斯沃尔德诉康涅狄格州案(Griswold v. Connecticut)和1972年艾森施塔特诉贝尔德案(Eisenstadt v. Baird)以来,避孕权一直受到美国宪法的保护。然而,即使有了这些宪法保护,保守的州议员对使用州立法避孕的直接攻击也越来越多。但支持生殖健康、权利和正义的州议员继续推动积极进取的立法和政策,保护避孕。州创新交易所(SiX)生殖权利团队于2018年启动了生殖自由领导委员会(RFLC),以支持支持以生殖健康、权利和正义为重点的进步政策的州立法者,其中包括跟踪和翻译有关计划生育和性、生殖和孕产妇健康的科学研究,并将他们与生成这些数据的研究人员联系起来。在本评论中,我们概述了州议员如何在其州倡导进步的避孕政策,并就州议员在RFLC网络中的研究作用提供了意见。我们这篇评论的目的是分享立法者自己的最佳实践和指导,关于研究人员如何在立法者反击保守派对身体自主权的攻击时使他们的研究更容易获得立法者。
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引用次数: 0
Contraceptive access initiatives and Title X: A synergistic partnership 避孕药具获取倡议和标题十:协同伙伴关系
IF 2.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-27 DOI: 10.1016/j.contraception.2025.111238
Elizabeth J. Jones, Michael S. Policar, Kimberly Diaz Scott
Synergy is the interaction or cooperation of two or more forces to produce a combined effect greater than the sum of their parts. As generators of new clinical knowledge for the sexual and reproductive health field and conveners for collaborative efforts to mobilize for state policy change, Contraceptive Access Initiatives (CAIs) have strengthened the Title X family planning program. Conversely, Title X is an essential source of care for millions of patients that face barriers to accessing contraceptive services. By linking CAIs with a broad and diverse network of service sites that stand to benefit from their innovations, the Title X program bridges research-to-practice gaps and supports improved population-level outcomes through changes in practice, systems, and policy. CAIs also can lean on Title X networks to support aspects of implementation and post-implementation sustainability, leveraging the broader scope of confidential services they provide at no cost or discounted rates, their training infrastructure, and the inroads they have built with community stakeholders and policymakers since the program’s inception over 50 years ago. Given the uncertainty of the current funding landscape, such partnerships are critical to keeping access points to person-centered contraceptive services open, particularly for individuals with low incomes, without insurance, and in need of confidential services.
协同作用是两种或两种以上力量的相互作用或合作,以产生比各部分之和更大的综合效果。作为性健康和生殖健康领域新的临床知识的创造者和动员国家政策变革的协作努力的召集人,获得避孕药具倡议加强了第十条计划生育方案。相反,第十条是数百万在获得避孕服务方面面临障碍的患者的重要护理来源。通过将cai与广泛而多样化的服务站点网络联系起来,这些站点有望从cai的创新中受益,《第十条》计划弥合了从研究到实践的差距,并通过实践、系统和政策的变革支持改善人口水平的成果。cai还可以依靠《第十条》网络来支持实施和实施后的可持续性,利用他们免费或折扣提供的更广泛的保密服务、他们的培训基础设施,以及他们自50多年前该计划启动以来与社区利益相关者和决策者建立的进展。鉴于目前筹资形势的不确定性,这种伙伴关系对于保持以人为本的避孕服务的可及性至关重要,特别是对于低收入、无保险和需要保密服务的个人。
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引用次数: 0
Association of over-the-counter birth control pill use and contraceptive autonomy among oral contraceptive users 口服避孕药使用者非处方避孕药使用与避孕自主的关系。
IF 2.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-27 DOI: 10.1016/j.contraception.2025.111253
Kimberly M. Schaefer , Haley Burns , Jonas J. Swartz , Alison B. Edelman , Maria I. Rodriguez

Objective

To evaluate the association between individuals’ experiences with healthcare and over-the-counter (OTC) pill use.

Study design

We conducted a cross-sectional online baseline survey of individuals aged 15–45 obtaining oral contraception (OTC or by prescription) for pregnancy prevention in a convenience sample across the United States (US). We collected demographic information, clinical information, and measured contraceptive autonomy using three validated measures: Contraceptive Agency Scale (CAS), the Person-Centered Contraceptive Care (PCCC) measure, and the Discrimination in Medical Settings (DMS) survey. We compared these characteristics between people using prescription and OTC pills and built logistic regression models to evaluate the association between OTC pill use and each of these three measures.

Results

Our sample included 497 individuals (OTC 22.5%, n = 112; prescription 77.5%, n = 385) who received contraceptive counseling within the past year. Compared to participants with a prescription, users of OTC pills were older, more commonly uninsured (18.8% vs. 2.9%, p < 0.001), on Medicaid (24.1% vs. 10.1%, p < 0.001), and more likely to be Black (18.8% vs. 5.7%, p < 0.001). Less than half of OTC pill users were already using a more effective method of contraception prior to survey completion, compared to the majority of prescription users (47.3% vs. 82.9%, p < 0.001). Based on adjusted multivariable models, key autonomy outcomes of low contraceptive agency and non person-contraceptive care were both associated with increased probability of OTC pill use.

Conclusion

The OTC pill may fill an important gap in improving contraception access, particularly among individuals with past negative healthcare interactions.

Implications

Our study suggests that individuals reporting lower contraceptive agency and less person-centered care are more likely to use over-the-counter than prescription oral contraception. Expanding over-the-counter access may reduce barriers for marginalized populations with poor healthcare interactions, supporting more equitable contraceptive access across diverse demographic and insurance groups in the U.S.
目的:评价个人医疗保健经历与非处方药(OTC)使用之间的关系。研究设计:我们进行了一项横断面在线基线调查,调查对象为年龄在15-45岁之间的个体,这些个体为了预防怀孕而在全美范围内获得口服避孕药(OTC或处方)。我们收集了人口统计信息、临床信息,并使用三种有效的测量方法来测量避孕自主性:避孕机构量表(CAS)、以人为中心的避孕护理(PCCC)测量和医疗环境中的歧视(DMS)调查。我们比较了使用处方药和非处方药的人群的这些特征,并建立了logistic回归模型来评估非处方药使用与这三个指标之间的关系。结果:我们的样本包括497名在过去一年内接受避孕咨询的患者(非处方22.5%,n = 112;处方77.5%,n = 385)。与有处方的参与者相比,OTC避孕药的使用者年龄较大,更常见的是没有保险(18.8%比2.9%)。结论:OTC避孕药可能填补了改善避孕可及性的重要空白,特别是在过去有负面医疗互动的个体中。含义:我们的研究表明,报告较低的避孕机构和较少以人为本的护理的个人更有可能使用非处方药而不是处方口服避孕药。扩大非处方药的使用范围可能会减少医疗保健互动不良的边缘化人群的障碍,支持在美国不同的人口和保险群体中更公平地获得避孕药具
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引用次数: 0
What is contraceptive access? A comprehensive, multi-level framework to inform research, policy, and practice 什么是避孕途径?一个全面的、多层次的框架,为研究、政策和实践提供信息。
IF 2.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-27 DOI: 10.1016/j.contraception.2025.111271
Riley J. Steiner , Sarah M. Axelson , Claudia Nuñez-Eddy , Kelsie Williams , Sonya Borrero , Sheila Desai , Jenny Dodson Mistry , Christina I. Fowler , Laura D. Lindberg , Isaac Maddow-Zimet , Whitney Rice , Corinne H. Rocca , Michael G. Smith , Tracey A. Wilkinson

Objectives

Despite the importance of access to contraception for sexual and reproductive well-being, there is a lack of consensus about what “contraceptive access” entails. We present a multi-level and multi-dimensional framework for conceptualizing contraceptive access and discuss how it can be used to inform research, policy, and practice.

Study design

As the foundation for the contraceptive access framework, we used the social-ecological model and two frameworks for health care access, along with findings from an environmental scan of literature relevant to contraceptive access. To develop an initial version, we aligned contraceptive access concepts with the broader conceptual frameworks. We refined our framework based on input from an expert workgroup.

Results

The conceptual framework includes multi-level modifiable factors (i.e., underlying factors that create the conditions of contraceptive access) and modification strategies (i.e., actionable interventions or approaches that can be used to change the modifiable determinants) aligned with six dimensions of access: awareness, availability, accessibility, accommodation, acceptability, and affordability. The modification strategies influence modifiable determinants, which create the access conditions for individual-level pathways to seeking and obtaining one’s preferred contraceptive method or long-acting reversible contraception removal services.

Conclusions

We call on the sexual and reproductive health community to apply the framework to inform research, policy, and clinical and public health practice. Specific applications include measure development, surveillance, policy advocacy, clinic-based quality improvement, and state-level contraceptive access initiatives. The opportunities and challenges of using the framework in these ways can inform how it evolves to best reflect contraceptive access.

Implications

The conceptual framework can provide a shared understanding of how contraceptive access can be restricted or expanded. The framework can be used to strengthen efforts to assess and improve contraceptive access so that it is just, person-centered, and attainable for all.
目标:尽管获得避孕药具对性健康和生殖健康很重要,但对“获得避孕药具”的含义缺乏共识。我们提出了一个多层次、多维度的框架来概念化避孕获取,并讨论了如何将其用于研究、政策和实践。研究设计:作为避孕药具获取框架的基础,我们使用了社会生态模型和两个医疗保健获取框架,以及与避孕药具获取相关文献的环境扫描结果。为了开发一个初始版本,我们将避孕获取概念与更广泛的概念框架结合起来。我们根据专家工作组的输入改进了我们的框架。结果:概念框架包括多层次的可修改因素(即,创造避孕获得条件的潜在因素)和修改策略(即,可操作的干预措施或方法,可用于改变可修改的决定因素),与可获得性的六个维度相一致:意识、可获得性、可及性、便利、可接受性和可负担性。修改策略影响可修改的决定因素,这为寻求和获得个人首选避孕方法或长效可逆避孕移除服务的个人层面途径创造了获取条件。结论:我们呼吁性健康和生殖健康社区应用该框架,为研究、政策、临床和公共卫生实践提供信息。具体应用包括措施制定、监测、政策宣传、基于诊所的质量改进和州级避孕措施获取倡议。以这些方式使用该框架的机遇和挑战可以为其如何演变以最好地反映避孕药具获取情况提供信息。含义:概念框架可以提供关于如何限制或扩大避孕药具获取的共同理解。该框架可用于加强评估和改善避孕药具获取的努力,使其公正、以人为本、人人可及。
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引用次数: 0
How statewide contraceptive access initiatives can advance sexual and reproductive health equity 全州避孕药具获取倡议如何促进性健康和生殖健康平等。
IF 2.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-27 DOI: 10.1016/j.contraception.2025.111248
Jessica Danaux, Nikita Malcolm, Jamie Hart
The Coalition to Expand Contraceptive Access and Emory University’s Center for Reproductive Health Research in the Southeast led a collaborative effort to convene statewide contraceptive access initiatives (SCAI) to identify opportunities to meaningfully advance sexual and reproductive health equity (SRHE) in ongoing and future initiatives. The effort engaged more than 40 stakeholders representing ten SCAI and assessed published literature to draw collective insights, successes, and lessons learned. This commentary outlines four concrete recommendations derived from this effort: (1) center communities in all phases of the initiative, (2) foster flexibility and responsiveness in initiative activities, (3) align goals with comprehensive measures, and (4) prioritize sustainable approaches. The commentary also explores how these recommendations connect to the principles of SRHE and how implementers, evaluators, funders, and supporters of contraceptive access initiatives can implement them to advance SRHE.
扩大避孕药具获取联盟和埃默里大学东南生殖健康研究中心领导了一项合作努力,召集全州避孕药具获取倡议(SCAI),以确定在正在进行和未来的倡议中有意义地推进性和生殖健康平等(SRHE)的机会。这项工作涉及了代表10个SCAI的40多个利益相关者,并评估了已发表的文献,以得出集体的见解、成功和经验教训。这篇评论概述了从这项工作中得出的四个具体建议:(1)在计划的所有阶段集中社区,(2)在计划活动中培养灵活性和响应性,(3)将目标与综合措施保持一致,(4)优先考虑可持续的方法。评论还探讨了这些建议如何与性健康和健康健康原则相联系,以及避孕措施获取倡议的实施者、评估者、资助者和支持者如何实施这些建议以推进性健康和健康健康。
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引用次数: 0
Evaluation of patient experiences with contraceptive counseling during the South Carolina Choose Well contraceptive access initiative 在南卡罗来纳选择良好的避孕途径倡议避孕咨询患者的经验评估
IF 2.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-27 DOI: 10.1016/j.contraception.2025.111246
Michael G. Smith , Liwen Zeng , Amal J. Khoury

Objective

Choose Well is the first statewide contraceptive access initiative in the southeastern US. Launched in 2017 in South Carolina (SC), Choose Well aims to reduce unintended pregnancy and increase access to evidence-based contraception. The initiative provided capacity building, training and infrastructure, and workforce support to clinical partners across SC. We assess the impact of Choose Well on patient-reported experiences with contraceptive counseling. Examining patient experiences in addition to contraceptive utilization is essential for assessing reproductive autonomy.

Study design

The Women’s Longitudinal Study collected data on contraceptive counseling experiences of patients recruited in Choose Well-participating (intervention) clinics and those recruited in comparison clinics in a demographically and culturally comparable state. Overall, 2221 eligible patients were recruited from 37 clinics. Patient experiences of person-centered counseling, overall satisfaction, and accessibility of post-appointment care were assessed. Multivariable linear regression and modified Poisson regression models assessed Choose Well’s impact on counseling experiences.

Results

Intervention clinic participants were more likely than comparison clinic participants to report that they received person-centered counseling (adjusted PR= 1.12; 95% CI: 1.00,1.25) and that providers verified that they could use their contraception correctly and consistently (aPR= 1.09; 95% CI: 1.02,1.18). No differences were found in the likelihood that patients reported being satisfied with their visit or leaving with the best method for them.

Conclusion

Choose Well implementation was associated with increased person-centered contraceptive counseling. Contraceptive access initiatives that prioritize optimal counseling along with equitable access to contraceptive methods can promote reproductive health and support women in achieving their reproductive goals.

Implications

Choose Well was associated with increases in person-centered contraceptive counseling while expanding access to contraceptive methods in SC. Ongoing and future SCAIs should prioritize equitable access to the full range of contraceptive methods and measures to assess and ensure that their efforts are not limiting the reproductive autonomy of patients.
目的“选择好”计划是美国东南部第一个全州范围内的避孕计划。2017年在南卡罗来纳州发起的“选择好”计划旨在减少意外怀孕,增加获得循证避孕措施的机会。该倡议为南卡罗来纳州的临床合作伙伴提供了能力建设、培训和基础设施以及劳动力支持。我们评估了“选择好”项目对患者报告的避孕咨询经历的影响。除了避孕药具的使用外,检查患者的经历对于评估生殖自主权至关重要。研究设计妇女纵向研究收集了在选择良好参与(干预)诊所招募的患者和在人口统计学和文化上可比较的比较诊所招募的患者的避孕咨询经验数据。总的来说,从37个诊所招募了2221名符合条件的患者。评估患者对以人为本的咨询、总体满意度和预约后护理的可及性的体验。多变量线性回归和修正泊松回归模型评估了选择好对咨询经验的影响。结果干预临床参与者比对照临床参与者更有可能报告他们接受了以人为中心的咨询(调整PR= 1.12; 95% CI: 1.00,1.25),提供者证实他们能够正确和持续地使用避孕措施(aPR= 1.09; 95% CI: 1.02,1.18)。在患者报告对他们的访问满意或以最好的方法离开的可能性方面没有发现差异。结论“选择好”的实施与以人为本的避孕咨询增加有关。优先考虑最佳咨询和公平获得避孕方法的避孕措施可促进生殖健康,并支持妇女实现其生殖目标。意义schoose Well与以人为中心的避孕咨询的增加有关,同时扩大了SC中避孕方法的可及性。正在进行和未来的SCAIs应优先考虑公平获得各种避孕方法和措施,以评估和确保他们的努力不会限制患者的生殖自主权。
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引用次数: 0
State-level contraceptive access policies and preventive sexual and reproductive health service use outcomes 国家级避孕药具获取政策和预防性和生殖健康服务使用成果。
IF 2.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-26 DOI: 10.1016/j.contraception.2025.111279
Whitney S. Rice , Sara K. Redd , Alina A. Luke , Sofia Filippa , Kimberly Jacob Arriola , Kelli Stidham Hall , Kelli Komro , Monica S. Aswani

Objective

Contraceptive access provides opportunity for related preventive health care. Thus, we explore whether changes in state contraceptive access policies relate to preventive health service use inequities.

Study design

We examined associations between a 2006–2017 state contraceptive access policy index and probabilities of individual-level receipt of pelvic exam, Pap test, and sexually transmitted infection (STI) services during the last year, as reported during time-corresponding cycles of the National Survey of Family Growth (NSFG). We used multivariate logistic regression and linear probability models, that accounted for survey weights and adjusted for individual- and state-level characteristics and state and year fixed effects. We further tested interaction effects by race/ethnicity, socioeconomic status, education, and sexual orientation.

Results

Among 21,537 NSFG respondents (mean age 29 years) from 2006 to 2017, 52% reported receiving a Pap test, 50% reported receiving a pelvic exam, and 20% reported receiving STI services. Main effects models testing the relationship between the contraceptive access policy index and the three outcomes among the entire population produced null findings. However, models testing interaction effects by social group found significant interactions between state contraceptive policy environments and individual-level race/ethnicity, education, income level, sexual orientation for receipt of Pap tests, pelvic exams, and STI services, revealing increased preventive services for certain social groups defined by lower education and income.

Conclusion

Individual preventive health service use associated with state contraceptive access environments varied by sociodemographic factors, highlighting the potential for state policy to act as a lever to alleviate inequities in access to care.

Implications

Overarchingly, more expansive contraceptive access is associated with increased preventive sexual and reproductive health care use for certain social groups. Thus, state policies expanding contraceptive access may mitigate broader inequities in access to care by facilitating opportunities for receipt of other preventive services, particularly Pap tests and pelvic exams.
目的:获得避孕药具为相关的预防保健提供机会。因此,我们探讨国家避孕政策的变化是否与预防性卫生服务使用不公平有关。研究设计:我们研究了2006-2017年国家避孕获取政策指数与去年个人接受盆腔检查、巴氏试验和性传播感染(STI)服务的概率之间的关系,这些都是在全国家庭增长调查(NSFG)的时间对应周期中报告的。我们使用多元逻辑回归和线性概率模型,这些模型考虑了调查权重,并调整了个人和州层面的特征以及州和年份的固定效应。我们进一步测试了种族/民族、社会经济地位、教育程度和性取向对相互作用的影响。结果:在2006-2017年的21,537名NSFG受访者(平均年龄29岁)中,52%的人报告接受了巴氏试验,50%的人报告接受了盆腔检查,20%的人报告接受了性传播感染服务。在整个人口中测试避孕措施获取政策指数与三个结果之间关系的主要效应模型没有发现任何结果。然而,测试社会群体相互作用效应的模型发现,国家避孕政策环境与个人层面的种族/民族、教育、收入水平、接受巴氏涂片检查的性取向、盆腔检查和性传播感染服务之间存在显著的相互作用,揭示了对某些受教育程度和收入较低的社会群体的预防服务增加。结论:与国家避孕药具获取环境相关的个人预防性卫生服务使用情况因社会人口因素而异,突出了国家政策作为杠杆缓解医疗服务获取不平等的潜力。意义:总体而言,更广泛的避孕药具获取与某些社会群体预防性和生殖保健使用的增加有关。因此,扩大获得避孕药具的国家政策可以通过促进接受其他预防性服务,特别是巴氏涂片检查和盆腔检查的机会,减轻在获得保健方面更广泛的不平等现象。
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引用次数: 0
Effects of tampon co-usage on the pharmacokinetics of segesterone acetate and ethinyl estradiol released from Annovera vaginal ring system 卫生棉条共用对阴道环系统释放的醋酸孕酮和雌二醇药动学的影响。
IF 2.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-20 DOI: 10.1016/j.contraception.2025.111274
Marlena G. Plagianos , Tracy X. Chen , Narender Kumar , Shelli Graham , Heather Sussman , Harvey Kushner , George Creasy , Brian Bernick , Lisa B. Haddad

Objectives

To evaluate effects of tampon co-usage on the pharmacokinetics of segesterone acetate (SA) and ethinyl estradiol (EE) released from Annovera Contraceptive Vaginal Ring System with a 21-day in/7-day out regimen.

Study design

We enrolled 24 participants in an open-label crossover study in Canada and the United States. Participants used combined oral contraceptive pills for 28 days before randomization (1:1) to either Annovera alone or Annovera while using four tampons daily on days 2–5 for one 28-day cycle; in the next cycle, participants switched treatments. We evaluated the steady-state interval for SA and EE from days 2-5 for concomitant Annovera and tampon use. We measured serum SA and EE using validated liquid chromatography-tandem mass spectrometry. The primary end point was the area under the curve (AUC) of SA and EE on cycle days 2-3 (AUC(2–3)). Bioequivalence is established if the 90% confidence interval (CI) of the geometric mean ratio (GMR) for AUC(2–3) is wholly contained within (0.80–1.25).

Results

We observed bioequivalence for SA with GMR of 0.98 (90% CI: 0.921, 1.043) and EE with GMR of 0.97 (90% CI: 0.91, 1.026), for AUC(2–3), and also for AUC from days 2-5 with GMRs of 1.02 (90% CI: 0.99, 1.06) for SA and 1.02 (90% CI: 0.97, 1.087) for EE. We observed no safety issues or serious adverse events.

Conclusions

Individuals using Annovera with 4 consecutive days of tampon use experienced no change in SA or EE absorption. Light/regular tampon co-usage for up to 4 consecutive days should not impact contraceptive efficacy or bleeding profile.

Implications

A significant proportion of reproductive-age women use tampons when experiencing vaginal bleeding; they can be reassured that tampon and contraceptive ring co-usage should not affect the contraceptive efficacy of the SA/EE contraceptive vaginal ring.
目的:评价卫生棉条同时使用对安诺维拉避孕环系统(CVS)释放的醋酸孕酮(SA)和雌二醇(EE)药代动力学(PK)的影响。研究设计:我们在加拿大和美国的开放标签交叉研究中招募了24名参与者。在随机分配(1:1)之前,参与者使用复方口服避孕药28天,要么使用安诺维拉和卫生棉条共同使用(在第2-5天每天使用四个卫生棉条,保持安诺维拉在原位),要么单独使用安诺维拉,一个28天的周期;在下一个周期中,参与者交换了治疗方法。我们评估了同时使用安诺维拉和卫生棉条的第2-5天的SA和EE的稳定状态间隔。我们使用完全验证的LCMS/MS方法测量每个时间点的血清SA和EE。主要的PK终点是第2-3天SA和EE的AUC(AUC(2-3))。如果AUC(2-3)的几何平均比(GMR)的90% CI完全包含在(0.80-1.25)内,则建立生物等效性。结果:我们观察到SA和EE的生物等效性,AUC(2-3)的GMRs分别为0.98 (90% CI: 0.921, 1.043)和0.97 (90% CI: 0.91, 1.026),第2天至第5天的AUC, SA和EE的GMRs分别为1.02 (90% CI: 0.99, 1.06)和1.02 (90% CI: 0.97, 1.087)。我们没有观察到明显的安全性问题或严重的不良事件。结论:连续4天使用棉条的个体对SA或EE的吸收没有变化。因此,少量/常规卫生棉条连续使用4天不应影响避孕效果或出血情况。意义声明:相当大比例的育龄妇女在阴道出血时使用卫生棉条;他们可以放心,卫生棉条和避孕环共同使用不应影响醋酸孕酮/乙炔雌二醇避孕阴道环的避孕效果。
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引用次数: 0
Pilot randomized control trial assessing interpersonal quality of contraceptive counseling via telephone vs video 评估电话与视频避孕咨询人际质量的先导随机对照试验。
IF 2.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-18 DOI: 10.1016/j.contraception.2025.111273
Emily Freeman , Rachel Paul , Megan Dorsey , Jennifer A. Reeves , Tessa Madden

Objectives

To compare the interpersonal quality of contraceptive counseling delivered via telephone vs video.

Study design

We conducted a pilot randomized controlled trial at a single Title X clinic. Staff informed patients about the study during appointment scheduling. Research staff contacted patients to assess for eligibility and interest, then enrolled and randomized participants to telephone- or video-based contraceptive counseling. Participants completed an electronic survey after counseling. The primary outcome was quality of contraceptive counseling, assessed using the Interpersonal Quality in Family Planning scale. Participants completed questions adapted from the Telehealth Usability Questionnaire, a validated measure of the quality of the telehealth services. We conducted intention-to-treat and per-protocol analyses for video vs telephone visits using appropriate bivariate tests.

Results

Between May 2022 and June 2023, 269 patients scheduled telehealth counseling appointments. We screened 245 (91%) for eligibility; 232 (95%) were eligible. Of the eligible participants, 214 (92%) were enrolled and randomized; 200 (94%) completed counseling and the survey. Participant demographics were similar between groups. In the intention-to-treat analysis, most participants in the video and telephone groups had high interpersonal quality of counseling, defined as a top score on Interpersonal Quality in Family Planning (80% vs 75%, p = 0.44); quality of counseling was similar for the per-protocol comparison (79% video vs 76% telephone, p = 0.62). Participants reported a high level of usability with both counseling modalities.

Conclusions

Participants reported high interpersonal quality with telephone and video visits for contraceptive counseling. Telephone-based telehealth can further increase access to care, especially for patients with limited access to web-based video conferencing.

Implications

We found similarly high interpersonal quality of contraceptive counseling performed via video and telephone telehealth visits. Our findings, along with others, can support policy changes to increase access to telephone-based telehealth.
目的:比较电话与视频避孕咨询的人际关系质量。研究设计:我们在一个单独的Title-X诊所进行了一项随机对照试验。工作人员在预约安排期间告知患者这项研究。研究人员联系患者,评估他们的资格和兴趣,然后随机招募参与者进行电话或视频避孕咨询。参与者在咨询后完成了一份电子调查。主要结果是避孕咨询的质量,使用计划生育人际关系质量(IQFP)量表进行评估。与会者完成了根据远程保健可用性调查表改编的问题,这是衡量远程保健服务质量的有效措施。我们使用适当的双变量测试对视频访问和电话访问进行意向治疗和协议分析。结果:在2022年5月至2023年6月期间,269名患者预约了远程医疗咨询。我们筛选了245例(91%)入选;232例(95%)符合条件。在符合条件的参与者中,214名(92%)被纳入并随机分配;200人(94%)完成了咨询和调查。两组参与者的人口统计数据相似。在意向治疗分析中,视频组和电话组的大多数参与者具有较高的人际咨询质量,定义为IQFP得分最高(80%对75%,p=0.44);每个方案比较的咨询质量相似(79%视频vs 76%电话,p=0.62)。参与者报告了两种咨询方式的高可用性。结论:受访者在电话和视频访问避孕咨询中表现出较高的人际关系质量。基于电话的远程保健可以进一步增加获得护理的机会,特别是对于无法使用基于网络的视频会议的患者。启示:我们发现通过视频和电话远程医疗访问进行的避孕咨询同样具有较高的人际质量。我们的研究结果以及其他研究结果可以支持政策变化,以增加获得基于电话的远程医疗的机会。
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引用次数: 0
Sex differences in beliefs regarding abortion access as a women’s health issue 将堕胎视为妇女健康问题的信念的性别差异。
IF 2.3 2区 医学 Q1 OBSTETRICS & GYNECOLOGY Pub Date : 2025-10-17 DOI: 10.1016/j.contraception.2025.111272
Anita Raj , Clare Daniel , Nicole E. Johns , Priyanka Patel , Namratha Rao , Latona Giwa

Objective

To assess sex differences in the belief that abortion access is important for women’s health.

Study design

A 2024 survey asked N = 3348 U.S. adults their agreement with this belief. Adjusted multinomial regression analyses were conducted.

Results

Most (58.3%), and a higher proportion of females than males, agreed with the statement. Subgroup analysis of sex by political leanings showed that observed sex differences in this belief holds for moderates with a trend seen for liberals and conservatives.

Conclusion

While most people agree with the statement, females across political leanings are more likely to endorse this belief compared to males.

Implications

The paper contributes to the discourse on abortion access as a health issue in the United States. We find that over half of U.S. participants agreed that abortion access is important for women's health, and females from across political parties were more likely than males to endorse this statement.
目的:评估在认为堕胎对妇女健康很重要方面的性别差异。研究设计:2024年的一项调查询问了N=3348名美国成年人是否同意这一观点。进行调整多项回归分析。结果:大多数人(58.3%)同意该说法,女性比例高于男性。性别与政治倾向的亚组分析表明,在这一信念中观察到的性别差异适用于温和派,也适用于自由派和保守派。结论:虽然大多数人同意这一说法,但与男性相比,不同政治倾向的女性更有可能支持这一观点。影响说明:本文有助于将堕胎作为美国的一个健康问题进行论述。我们发现,超过一半的美国参与者同意堕胎对女性健康很重要,而且来自各个政党的女性比男性更有可能赞同这一说法。
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引用次数: 0
期刊
Contraception
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