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Cellular and Molecular Machinery of Neuropathic Pain: an Emerging Insight 神经性疼痛的细胞和分子机制:一个新兴的见解
Q1 Biochemistry, Genetics and Molecular Biology
Current Pharmacology Reports
Pub Date : 2022-05-23 DOI: 10.1007/s40495-022-00294-9
Shabnam Ameenudeen, Mohd. Kashif, Subhamoy Banerjee, H. Srinivasan, A. Pandurangan, M. Waseem
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引用次数: 1
Moringa Tree, Gift of Nature: a Review on Nutritional and Industrial Potential 辣木树，大自然的礼物:营养和工业潜力综述
Q1 Biochemistry, Genetics and Molecular Biology
Current Pharmacology Reports
Pub Date : 2022-05-16 DOI: 10.1007/s40495-022-00288-7
S. Patil, B. Mohite, Kiran R. Marathe, N. Salunkhe, V. Marathe, V. Patil
{"title":"Moringa Tree, Gift of Nature: a Review on Nutritional and Industrial Potential","authors":"S. Patil, B. Mohite, Kiran R. Marathe, N. Salunkhe, V. Marathe, V. Patil","doi":"10.1007/s40495-022-00288-7","DOIUrl":"https://doi.org/10.1007/s40495-022-00288-7","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"8 1","pages":"262 - 280"},"PeriodicalIF":0.0,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47515568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Foresight on Phytoconstituents and Associated Pharmacological Activities of Traditional Medicinal Plant: Saussurea costus (Falc.) Lipschitz 中药材雪莲的植物成分及相关药理活性展望
Q1 Biochemistry, Genetics and Molecular Biology
Current Pharmacology Reports
Pub Date : 2022-04-25 DOI: 10.1007/s40495-022-00287-8
M. Vijayalakshmi, A. Umamaheswari, B. Agalya, S. N. Jegasubramaniam, S. L. Prabu
{"title":"Foresight on Phytoconstituents and Associated Pharmacological Activities of Traditional Medicinal Plant: Saussurea costus (Falc.) Lipschitz","authors":"M. Vijayalakshmi, A. Umamaheswari, B. Agalya, S. N. Jegasubramaniam, S. L. Prabu","doi":"10.1007/s40495-022-00287-8","DOIUrl":"https://doi.org/10.1007/s40495-022-00287-8","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"8 1","pages":"281 - 289"},"PeriodicalIF":0.0,"publicationDate":"2022-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49524435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Applications of Nanoscaffolds in Tissue Engineering 纳米支架在组织工程中的应用
Q1 Biochemistry, Genetics and Molecular Biology
Current Pharmacology Reports
Pub Date : 2022-04-06 DOI: 10.1007/s40495-022-00284-x
B. Deepika, A. Gopikrishna, A. Girigoswami, M. N. Banu, K. Girigoswami
{"title":"Applications of Nanoscaffolds in Tissue Engineering","authors":"B. Deepika, A. Gopikrishna, A. Girigoswami, M. N. Banu, K. Girigoswami","doi":"10.1007/s40495-022-00284-x","DOIUrl":"https://doi.org/10.1007/s40495-022-00284-x","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"8 1","pages":"171 - 187"},"PeriodicalIF":0.0,"publicationDate":"2022-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43272748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Molecular Docking as a Potential Approach in Repurposing Drugs Against COVID-19: a Systematic Review and Novel Pharmacophore Models 分子对接作为抗COVID-19药物再利用的潜在途径:系统综述和新的药效团模型
Q1 Biochemistry, Genetics and Molecular Biology
Current Pharmacology Reports
Pub Date : 2022-04-01 DOI: 10.1007/s40495-022-00285-w
M. Fadlalla, M. Ahmed, Musab M. Ali, Abdulrhman A. Elshiekh, B. Yousef
{"title":"Molecular Docking as a Potential Approach in Repurposing Drugs Against COVID-19: a Systematic Review and Novel Pharmacophore Models","authors":"M. Fadlalla, M. Ahmed, Musab M. Ali, Abdulrhman A. Elshiekh, B. Yousef","doi":"10.1007/s40495-022-00285-w","DOIUrl":"https://doi.org/10.1007/s40495-022-00285-w","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"8 1","pages":"212 - 226"},"PeriodicalIF":0.0,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42448433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Ethnobotany, Phytochemistry and Pharmacology of Palash (Butea monosperma (Lam.) Taub.): a Systematic Review 白刺(Butea monosperma, Lam.)的民族植物学、植物化学和药理《系统性评论》
Q1 Biochemistry, Genetics and Molecular Biology
Current Pharmacology Reports
Pub Date : 2022-03-29 DOI: 10.1007/s40495-022-00286-9
P. Kumari, Kirti Raina, S. Thakur, Rohit Sharma, N. Cruz-Martins, Pardeep Kumar, K. Barman, Swati Sharma, Dileep Kumar, P. Prajapati, Rohit Sharma, A. Chaudhary
{"title":"Ethnobotany, Phytochemistry and Pharmacology of Palash (Butea monosperma (Lam.) Taub.): a Systematic Review","authors":"P. Kumari, Kirti Raina, S. Thakur, Rohit Sharma, N. Cruz-Martins, Pardeep Kumar, K. Barman, Swati Sharma, Dileep Kumar, P. Prajapati, Rohit Sharma, A. Chaudhary","doi":"10.1007/s40495-022-00286-9","DOIUrl":"https://doi.org/10.1007/s40495-022-00286-9","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"8 1","pages":"188 - 204"},"PeriodicalIF":0.0,"publicationDate":"2022-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48406450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Smart Polymer-Based Reduction Responsive Therapeutic Delivery to Cancer Cells 智能聚合物为基础的减少响应治疗递送癌细胞
Q1 Biochemistry, Genetics and Molecular Biology
Current Pharmacology Reports
Pub Date : 2022-02-21 DOI: 10.1007/s40495-022-00282-z
Karthick Harini, P. Pallavi, Pemula Gowtham, K. Girigoswami, A. Girigoswami
{"title":"Smart Polymer-Based Reduction Responsive Therapeutic Delivery to Cancer Cells","authors":"Karthick Harini, P. Pallavi, Pemula Gowtham, K. Girigoswami, A. Girigoswami","doi":"10.1007/s40495-022-00282-z","DOIUrl":"https://doi.org/10.1007/s40495-022-00282-z","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"8 1","pages":"205 - 211"},"PeriodicalIF":0.0,"publicationDate":"2022-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42638652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Anti-Disialoganglioside-2 Monoclonal Antibodies as an Emerging Therapeutic Approach in Treatment of High-Risk Neuroblastoma 抗鼠尾神经节苷脂-2单克隆抗体作为治疗高危神经母细胞瘤的新方法
Q1 Biochemistry, Genetics and Molecular Biology
Current Pharmacology Reports
Pub Date : 2022-02-05 DOI: 10.1007/s40495-022-00281-0
H. Kumar, Rachna Gupta
{"title":"Anti-Disialoganglioside-2 Monoclonal Antibodies as an Emerging Therapeutic Approach in Treatment of High-Risk Neuroblastoma","authors":"H. Kumar, Rachna Gupta","doi":"10.1007/s40495-022-00281-0","DOIUrl":"https://doi.org/10.1007/s40495-022-00281-0","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"8 1","pages":"112 - 120"},"PeriodicalIF":0.0,"publicationDate":"2022-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48497842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomarkers from Secondary Complications in Spinal Cord Injury. 脊髓损伤继发性并发症的生物标志物。
Q1 Biochemistry, Genetics and Molecular Biology
Current Pharmacology Reports
Pub Date : 2022-02-01 Epub Date: 2021-12-02 DOI: 10.1007/s40495-021-00268-3
Hani Alostaz, Li Cai

Purpose of review: In the USA, spinal cord injury (SCI) occurs in 40 people per million every year due to events such as car accidents, falls, violence, or sports injury. Secondary complications that arise from SCI are life-threatening and should be treated as early as possible. In some cases, it is not completely obvious what complication a patient may have until it is too late. Therefore, biomarkers are required to assess the levels of secondary complications after SCI. As there are several complications that pose different warning signs, different biomarkers may be beneficial in early detection, maintenance, and long-term care for patients with SCI.

Recent findings: Numerous studies have been conducted on biomarkers in various SCI and its related complications, such as neuropathic pain and deep vein thrombosis. In recent years, research has expanded with biomarkers discovered by cellular and molecular, genome-wide transcriptomic analysis, bioinformatics, and clinical studies. Biomarkers have allowed early prediction of the severity of secondary complications due to SCI.

Summary: In this review, we summarize recent studies on the common biomarkers for the secondary complications related to SCI. We highlight the reliable biomarkers that have been tested, e.g., sclerostin, NGF, D-dimer, oncostatin M (OSM), microbiota, and C-reactive protein, which are valuable and with clinical importance. This review also emphasizes continuing research in biomarkers as they can provide valuable cellular and molecular insight into secondary complications after SCI.

回顾目的:在美国，由于车祸、跌倒、暴力或运动损伤等事件，每年每百万人中就有40人发生脊髓损伤(SCI)。脊髓损伤引起的继发性并发症是危及生命的，应尽早治疗。在某些情况下，患者可能出现的并发症并不完全明显，直到为时已晚。因此，需要生物标志物来评估脊髓损伤后继发并发症的水平。由于有几种并发症会产生不同的预警信号，不同的生物标志物可能对脊髓损伤患者的早期发现、维持和长期护理有益。近期研究发现:对各种脊髓损伤及其相关并发症，如神经性疼痛和深静脉血栓形成的生物标志物进行了大量研究。近年来，随着细胞和分子、全基因组转录组分析、生物信息学和临床研究发现生物标志物，研究范围不断扩大。生物标志物可以早期预测脊髓损伤继发性并发症的严重程度。摘要:本文综述了近年来有关脊髓损伤继发性并发症的常见生物标志物的研究进展。我们强调已经测试过的可靠的生物标志物，如硬化蛋白、NGF、d -二聚体、抑癌素M (OSM)、微生物群和c反应蛋白，这些都是有价值的，具有临床重要性。这篇综述还强调了生物标志物的持续研究，因为它们可以为脊髓损伤后的继发性并发症提供有价值的细胞和分子见解。
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引用次数: 2
Phytochemicals in Breast Cancer-Induced Osteoclastogenesis and Bone Resorption: Mechanism and Future Perspective 植物化学物质在乳腺癌诱导的破骨细胞发生和骨吸收中的作用:机制和未来展望
Q1 Biochemistry, Genetics and Molecular Biology
Current Pharmacology Reports
Pub Date : 2022-01-22 DOI: 10.1007/s40495-021-00279-0
S. Pore, Eun-Ryeong Hahm
{"title":"Phytochemicals in Breast Cancer-Induced Osteoclastogenesis and Bone Resorption: Mechanism and Future Perspective","authors":"S. Pore, Eun-Ryeong Hahm","doi":"10.1007/s40495-021-00279-0","DOIUrl":"https://doi.org/10.1007/s40495-021-00279-0","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"8 1","pages":"130 - 148"},"PeriodicalIF":0.0,"publicationDate":"2022-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"52806178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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