Pub Date : 2023-06-26DOI: 10.1007/s40495-023-00326-y
Surya P. Singh, A. Asch, C. Rao, Venkateshwar Madka
{"title":"Bladder Cancer Prevention: Potential Molecular Targets and Their Clinically Relevant Agents","authors":"Surya P. Singh, A. Asch, C. Rao, Venkateshwar Madka","doi":"10.1007/s40495-023-00326-y","DOIUrl":"https://doi.org/10.1007/s40495-023-00326-y","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"9 1","pages":"275 - 283"},"PeriodicalIF":0.0,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44656014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Understanding Alzheimer’s Disease by Targeting Gut Microbiota and Role of Heavy Metals: Insight from Novel Therapeutical Approach","authors":"Anjalee Bhratee, Mayank Kumar, Md Reyaz Alam, Piyush Anand, Shamsher Singh","doi":"10.1007/s40495-023-00325-z","DOIUrl":"https://doi.org/10.1007/s40495-023-00325-z","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"9 1","pages":"177 - 197"},"PeriodicalIF":0.0,"publicationDate":"2023-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43594365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-06DOI: 10.1007/s40495-023-00321-3
V. Sandhiya, K. Senthilkumaran, U. Ubaidulla
{"title":"Signal Passageway of Phenolic Acid in Opposition to Malignancy Management","authors":"V. Sandhiya, K. Senthilkumaran, U. Ubaidulla","doi":"10.1007/s40495-023-00321-3","DOIUrl":"https://doi.org/10.1007/s40495-023-00321-3","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"9 1","pages":"247 - 259"},"PeriodicalIF":0.0,"publicationDate":"2023-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42120344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-01DOI: 10.1007/s40495-023-00322-2
D. Nath, Baishakhi Bairagi, Farhin R Khan
{"title":"Phytoconstituents for Boosting the Stem Cells Used in Regenerative Medicine","authors":"D. Nath, Baishakhi Bairagi, Farhin R Khan","doi":"10.1007/s40495-023-00322-2","DOIUrl":"https://doi.org/10.1007/s40495-023-00322-2","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"9 1","pages":"228 - 246"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46452928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-25DOI: 10.1007/s40495-023-00319-x
V. Ponnala, Pavankumar Narapaka, P. Garapati, G. Vishwas, A. Imam, Sameer Dhingra
{"title":"Exploring the Association Between Statin Use and the Risk of Pancreatic Cancer: an Updated Meta-analysis of Observational Studies","authors":"V. Ponnala, Pavankumar Narapaka, P. Garapati, G. Vishwas, A. Imam, Sameer Dhingra","doi":"10.1007/s40495-023-00319-x","DOIUrl":"https://doi.org/10.1007/s40495-023-00319-x","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"9 1","pages":"167 - 176"},"PeriodicalIF":0.0,"publicationDate":"2023-05-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47681560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-18DOI: 10.1007/s40495-023-00320-4
Kingsley E W Walker, Reshma Bankay, Satish Jankie, Sameer Dhingra
Purpose of overview: The constant surge in accessing essential medicines creates a greater need for continuous monitoring of usage. The inability to source active pharmaceutical ingredients during the COVID-19 pandemic resulted in drug shortages that increased online requests for medications. E-commerce and social sites have opened the floodgate for the marketing of falsified, substandard, and unregistered pharmaceuticals, making them easily accessible to consumers with the click of a button. A high prevalence of such products with compromised quality highlights further the need for enhanced post-marketing vigilance of safety and quality within the pharmaceutical industry. This review aims to assess the extent to which pharmacovigilance (PV) systems in selected Caribbean countries conform to the minimum World Health Organization (WHO) requirements, highlight the importance of PV in ensuring the safer use of medicines across the Caribbean region, and identify opportunities and challenges in building comprehensive PV systems.
Recent findings: The review finds that while major advancements in PV and adverse drug reaction (ADR) monitoring have occurred in Europe and other parts of the Americas, little has been done in the Caribbean region. Only a few countries in the region are active members of the WHO's global PV network, and ADR reporting is minimal. The reason for low reporting includes a lack of awareness, commitment, and participation of healthcare professionals, manufacturers, authorized distributors, and the general consumers.
Summary: Nearly all established national PV systems do not fully conform to the minimum PV requirements by the WHO. Legislation, regulatory framework, political commitment, adequate funding, strategies, and incentives to encourage reporting of ADRs are needed to build sustainable PV systems in the Caribbean.
{"title":"Pharmacovigilance in the Caribbean Countries: an Overview.","authors":"Kingsley E W Walker, Reshma Bankay, Satish Jankie, Sameer Dhingra","doi":"10.1007/s40495-023-00320-4","DOIUrl":"10.1007/s40495-023-00320-4","url":null,"abstract":"<p><strong>Purpose of overview: </strong>The constant surge in accessing essential medicines creates a greater need for continuous monitoring of usage. The inability to source active pharmaceutical ingredients during the COVID-19 pandemic resulted in drug shortages that increased online requests for medications. E-commerce and social sites have opened the floodgate for the marketing of falsified, substandard, and unregistered pharmaceuticals, making them easily accessible to consumers with the click of a button. A high prevalence of such products with compromised quality highlights further the need for enhanced post-marketing vigilance of safety and quality within the pharmaceutical industry. This review aims to assess the extent to which pharmacovigilance (PV) systems in selected Caribbean countries conform to the minimum World Health Organization (WHO) requirements, highlight the importance of PV in ensuring the safer use of medicines across the Caribbean region, and identify opportunities and challenges in building comprehensive PV systems.</p><p><strong>Recent findings: </strong>The review finds that while major advancements in PV and adverse drug reaction (ADR) monitoring have occurred in Europe and other parts of the Americas, little has been done in the Caribbean region. Only a few countries in the region are active members of the WHO's global PV network, and ADR reporting is minimal. The reason for low reporting includes a lack of awareness, commitment, and participation of healthcare professionals, manufacturers, authorized distributors, and the general consumers.</p><p><strong>Summary: </strong>Nearly all established national PV systems do not fully conform to the minimum PV requirements by the WHO. Legislation, regulatory framework, political commitment, adequate funding, strategies, and incentives to encourage reporting of ADRs are needed to build sustainable PV systems in the Caribbean.</p>","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":" ","pages":"1-11"},"PeriodicalIF":0.0,"publicationDate":"2023-05-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10191812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10092389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-02DOI: 10.1007/s40495-023-00317-z
Suneel Kumar, R. P. Aharwal, Deeksha Singh, D. Mishra, A. Sarangi, R. K. Mohapatra, A. Sharma, S. Sandhu
{"title":"Isolation and Chemical Structural Elucidation of Antibacterial Bioactive Compounds from Endophytic Fungal Strain Phoma sp. D1","authors":"Suneel Kumar, R. P. Aharwal, Deeksha Singh, D. Mishra, A. Sarangi, R. K. Mohapatra, A. Sharma, S. Sandhu","doi":"10.1007/s40495-023-00317-z","DOIUrl":"https://doi.org/10.1007/s40495-023-00317-z","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"9 1","pages":"128 - 143"},"PeriodicalIF":0.0,"publicationDate":"2023-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48829804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-18DOI: 10.1007/s40495-023-00315-1
Tanaya R. Vaidya, Yesenia Franco, S. Ait-Oudhia
{"title":"Correction to: A Three-dimensional and Dynamic (3DD) Cell Culture System for Evaluation of Pharmacokinetics, Safety and Efficacy of Anti-cancer Drugs","authors":"Tanaya R. Vaidya, Yesenia Franco, S. Ait-Oudhia","doi":"10.1007/s40495-023-00315-1","DOIUrl":"https://doi.org/10.1007/s40495-023-00315-1","url":null,"abstract":"","PeriodicalId":11139,"journal":{"name":"Current Pharmacology Reports","volume":"9 1","pages":"154 - 154"},"PeriodicalIF":0.0,"publicationDate":"2023-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46003723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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