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Etiology and outcome of hematospermia :A prospective study 血精症的病因和预后:一项前瞻性研究
Pub Date : 2023-10-30 DOI: 10.26505/djm.25017131211
Measar Karim Hadaia
Background: Although hematospermia is not common but considered an alarming symptom for patient and doctor. The cause of this worry is that it has been described as a dangerous symptom of prostate cancer by the patients and the health workers. Objective: To classify the causes and outcome of hematospermia. Patients and Methods: : This is a prospective study of patients newly diagnosed with hematospermia-diagnosed and treated in private clinic and hospital over a period of 4 years (2018-2022). Data collection and recording done related to demographic, symptomatology, clinical finding, investigations, treatment given and the outcome during 6 months of follow up. Results: One hundred and six patients with hematospermia were seen in the private clinic and hospital. The mean age was 40 years (25-70). Thirty-six (33.9%) patients were diagnosed as prostatitis clinically or by positive seminal fluid culture. Only (4) patients had prostate carcinoma with only one new case and the other three were known cases of prostate cancer already on treatment. With (4) cases had thrombocytopenia and (2) cases with sickle cell anemia and (1) case each prostate cyst and severe hypertension and vesical stone. (2) cases on anticoagulant therapy. And another (2) cases with history of epididymal surgery. There was no identifiable cause in the remaining 53 patients (50%). Conclusion: the majority of patients presented with hematospermia were below 50 years and have benign etiology and most of them were self-limited and less than 1% of cases revealed new prostate cancer. So, we can confidently reassure a patient presented with hematospermia due to benign nature of the disease in the majority of patients, especially in young patients.
背景:虽然血精并不常见,但对患者和医生来说都是一个值得警惕的症状。造成这种担忧的原因是,患者和卫生工作者将其描述为前列腺癌的一种危险症状。目的:分析血精症的病因及转归。患者和方法:这是一项前瞻性研究,研究对象是在私人诊所和医院诊断和治疗的新诊断为血精症的患者,为期4年(2018-2022)。在6个月的随访期间,收集和记录与人口统计学、症状学、临床发现、调查、给予的治疗和结果有关的数据。结果:我院门诊及医院共收治血精患者106例。平均年龄40岁(25-70岁)。36例(33.9%)临床诊断为前列腺炎或精液培养阳性。只有(4)例患者患有前列腺癌,其中只有一例新发病例,其他3例是已知的已经接受治疗的前列腺癌病例。其中(4)例有血小板减少症,(2)例有镰状细胞性贫血,(1)例有前列腺囊肿、严重高血压和膀胱结石。(2)抗凝治疗病例。2例有附睾手术史。其余53例(50%)患者无明确病因。结论:以血精患者为主,年龄在50岁以下,为良性病因,多为自限性,新发前列腺癌不到1%。因此,我们可以自信地向大多数患者,特别是年轻患者保证,由于疾病的良性性质而出现血精。
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引用次数: 0
Molecular prevalence of MecA and Blaz Genes with phenotypic analysis of Antibiotic Sensitivity Pattern for S.aureus Isolated From Dermal lesions of Sheep Breeders In Diyala Governorate – Iraq MecA和Blaz基因在伊拉克迪亚拉省绵羊养殖者皮肤病变中分离的金黄色葡萄球菌的分子流行及抗生素敏感性表型分析
Pub Date : 2023-10-30 DOI: 10.26505/djm.2516940912
Zainab Bressam Fajer, Ali Ibrahim Ali Al-Ezzy, Ahmed H. AL-Zuhairi
Background: S. aureus is one of the dominant bacterial pathogens among dermal infections in human and animals, which have resistance to different antimicrobial drugs. Objective: Isolation and identification of S.aureus from skin lesions among sheep breeders by traditional methods, Vitek 2 system and PCR using Staur 4, 6 specific pri-mers for validation, Detection of genes (methicillin resistant (mecA), Beta- lac-tamase gene (blaZ) by conventional PCR ,determine antibiotic sensitivity pat-tern by kirby bauer disc diffusion method. Patients and Methods: A total of 44 swaps were collected from sheep breeders suffered from variety of infected skin lesions to detect methicillin sensitive and resistant s. aureus by employing traditional methods in addition to confirmatory techniques through fast rapid VETEK2 system , detection of genes (methicillin resistant (mecA), Be-ta- lactamase gene (blaZ) by conventional PCR , and determine antibiotic sensi-tivity pattern by kirby bauer disc diffusion method. Results: S.aureus was isolated from 15/44,( 34.09%) of skin lesion of sheep breeders . A total of 6/15 ,(40%) were methicillin resistant S.aureus (MRSA) ,which represent ( 13.63%) from total samples .Beta lactamase gene primers was detected in all S.aureus isolates. A 6/15,(40%) of S.aureus have resistance for members of antibiotics classes, penicillins, polypeptides, fluoroquinolones, macrolide which include the following : methicillin that was confirmed early by detection of me-cA gene , levofloxacin , ofloxacin , erythromycin and vancomycin. A 6/15,(40%) of S.aureus have multidrug resistant trait for Penicillins, Polypep-tides, Fluoroquinolones, Macrolide antibiotics. Non multidrug resistant S.aureus was reported for Penicillins (oxacillin,4/15, 26%) and Polypeptides antibiotics (vancomycin 8/15, 53.33%) of S.aureus . Absolute sensitivity was reported for gentamycin, tetracycline, rifampicin, imipenem and chloramphenicol. Conclusion: Methicillin sensitive S.aureus was more common compared with MRSA isolated from dermal infections of sheep breeders. Blaz gene was predominantly ex-pressed by S.aureus isolates followed by Mec A gene. S.aureus have resistance for penicillins, polypeptides, fluoroquinolones, macrolide which include the fol-lowing : methicillin, levofloxacin , ofloxacin , erythromycin and vancomycin . S.aureus have multidrug resistant trait for Penicillins, Polypeptides, Fluoroquin-olones, Macrolide antibiotics. S.aureus was absolutely sensitive to gentamycin, tetracycline, rifampicin, imipenem and chloramphenicol.
背景:金黄色葡萄球菌是人畜皮肤感染的主要病原菌之一,对多种抗菌药物具有耐药性。目的:采用传统方法、Vitek 2系统和Staur 4、6特异性引物对金黄色葡萄球菌进行分离鉴定,采用常规PCR方法检测耐甲氧西林(mecA)、β -内酰胺酶基因(blaZ),采用kirby bauer盘扩散法测定抗生素敏感型。患者和方法:收集各种皮肤感染病变的绵羊养殖户共44只交换体,除采用传统方法检测甲氧西林敏感和耐药金黄色葡萄球菌外,采用快速快速VETEK2系统,采用常规PCR检测基因(甲氧西林耐药基因(mecA)、Be-ta-内酰胺酶基因(blaZ),采用kirby bauer盘扩散法检测抗生素敏感型。结果:从绵羊养殖者皮肤损伤中分离出金黄色葡萄球菌15/44,占34.09%。耐甲氧西林金黄色葡萄球菌(MRSA)共6/15(40%),占总样本的13.63%。所有金黄色葡萄球菌分离株均检测到β -内酰胺酶基因引物。6/15(40%)的金黄色葡萄球菌对抗生素类成员、青霉素类、多肽类、氟喹诺酮类、大环内酯类耐药,其中包括:通过me-cA基因检测早期确认的甲氧西林、左氧氟沙星、氧氟沙星、红霉素和万古霉素。6/15(40%)金黄色葡萄球菌对青霉素类、多肽类、氟喹诺酮类、大环内酯类抗生素具有多重耐药特征。金黄色葡萄球菌中青霉素类(4/15,26%)和多肽类抗生素(万古霉素8/15,53.33%)检出非耐多药金黄色葡萄球菌。庆大霉素、四环素、利福平、亚胺培南和氯霉素均有绝对敏感性。结论:对甲氧西林敏感的金黄色葡萄球菌比从绵羊养殖户皮肤感染中分离的MRSA更为常见。金黄色葡萄球菌主要表达Blaz基因,其次是Mec A基因。金黄色葡萄球菌对青霉素、多肽、氟喹诺酮类药物、大环内酯类药物有耐药性,其中包括:甲氧西林、左氧氟沙星、氧氟沙星、红霉素和万古霉素。金黄色葡萄球菌对青霉素类、多肽类、氟喹酮类、大环内酯类抗生素具有多重耐药特征。金黄色葡萄球菌对庆大霉素、四环素、利福平、亚胺培南和氯霉素绝对敏感。
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引用次数: 0
The effect of the ectoparasite (Pediculus humanus capitis) on immunological and blood parameters in children of different ages in Baquba city 巴曲巴市不同年龄儿童头皮虫对免疫及血液指标的影响
Pub Date : 2023-10-30 DOI: 10.26505/djm.25017031023
Hasnaa Khalid Awaad, Sanaa Nagem Abed Alhadidi, Talib Jawad Kadhim
Background: Ectoparasites are predominant parasitic infections among children. Head lice (Pediculus humanus capitis) are transmitted parasites, mainly among school-aged children. Although, head lice are not a chief health hazardor or a vector for disease, they are a public social problem. The transmitted infections by a parasitic bite, may reach the blood which causes health problems for children and affects their health. Objective: To investigate the effects of infection with head lice on Immunoglobulin E (IgE), vitamin D3, Zinc, and blood parameters. Patients and Methods: Samples including skin swapping and blood samples were collected from 300 children who were examined at AL-Batool Maternity Teaching Hospital (AL-BMTH) and some medical centers. Skin scraping and swapping were examined microscopically for detection of the parasite. Blood samples were analyzed for immunological and blood parameter estimation, during the period from 1st October 2021 to the end of May 2022. Samples were sent to the parasitology and hematology laboratories in AL-BMTH to identify the parasitic infections and their effects. Results: The samples include 180 females and 120 males, 90 samples of the 300 were epidemic with lice infection, 48.9% of them were at age 1-5 years, 35.6% were at age 6-10 and 15.6 % were at age 11-15, 91% of the infected children were females, while only 9 % of the infected children were males. The blood analysis indicated that the levels of vitamin D and the mineral Zinc, were lower in children infected with head lice compared to the control, while IgE was higher. RBC and Hb showed a lower level in infected children than in control, whereas WBC was at a high ratio in most patients. Conclusion: Parasites cause many diseases in children in particular. They spread in rural and crowded places and affect the activity and vitality of children.
背景:外寄生虫是儿童中主要的寄生虫感染。头虱是一种传染性寄生虫,主要在学龄儿童中传播。虽然头虱不是主要的健康危害或疾病媒介,但它们是一个公共社会问题。通过寄生虫叮咬传播的传染病可能会进入血液,给儿童带来健康问题并影响他们的健康。目的:探讨头虱感染对免疫球蛋白E (IgE)、维生素D3、锌及血液指标的影响。患者和方法:收集了在AL-Batool妇产教学医院和一些医疗中心接受检查的300名儿童的样本,包括皮肤交换和血液样本。皮肤刮痧和交换显微镜检查寄生虫的检测。对2021年10月1日至2022年5月底期间的血液样本进行免疫学和血液参数估计分析。将样本送到医院的寄生虫学和血液学实验室,以确定寄生虫感染及其影响。结果:300份样本中,女性180份,男性120份,流行虱感染90份,其中1 ~ 5岁占48.9%,6 ~ 10岁占35.6%,11 ~ 15岁占15.6%,感染儿童中91%为女性,仅9%为男性。血液分析表明,与对照组相比,感染头虱的儿童体内维生素D和矿物质锌的含量较低,而IgE含量较高。感染儿童的RBC和Hb水平低于对照组,而WBC在大多数患者中比例较高。结论:寄生虫可引起多种疾病,尤其是儿童。它们在农村和拥挤的地方传播,影响儿童的活动和活力。
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引用次数: 0
Knowledgment of Birth Spacing Among Women Attending Primary Health Care Centers in Mukalla District, Yemen 也门穆卡拉地区初级卫生保健中心的妇女对生育间隔的了解
Pub Date : 2023-06-30 DOI: 10.26505/djm.24027121211
Najla Saeed Abaddan, Asrar Saleh Sayad, Jalil I Alezzi
Background: Short birth spacing linked with adversative health consequences for infant, child and maternal mortality also increases the chances of mother and their children survival. Objective: To assess the determinants and the knowledge of birth space amongst women of reproductive age in Mukalla district, Hadhramout Governorate, Yemen. Patients and Methods: A cross sectional study of 384 women of multiplicative ages (15-49 years) was conducted at primary health care centres in Mukalla district. The study was conducted from November. 2018 to Oct 2019. Results: The median birth spacing was 35 months. (50.8 %) of respondents have been committed undersized birth spacing underneath the indorsed interval of ideal delivery spacing. Multivariate logestic V regression revealed that age of mother between 15-24 years (OR 3.255, 95%CI 1.598-6.629, P=0.001), not enough family income (OR 1.867, 95%CI1.104-3.158, P =0.020 ), number of living children ≤ 3 children (OR 1.225, 95%CI .532–2.520, P=0.027) and breast feeding duration < 6 months (OR7.435 , 95%CI 1.490 – 37.101,P=0.014) or 6-<12 months (OR 7.320, 95%CI 1.406–38.116, P=0.018) were linked with augmented hazard of short birth spacing, whereas mother’s history of chronic disease (OR.026,95%CI .003-.227,P=.001) and modern family planning methods utilization (OR.208, 95%CI.112-.386, P=0.000) were linked with decreased risk of little birth space. (58.1%) of respondents had high level of knowledge about the birth spacing. Conclusion: Certain factors were significant predictors of short birth spacing in Mukalla's women. This should lead to encouragement of longer birth spacing between births. Keywords: Birth spacing; knowledgment; primary health care centers; Yemen
背景:与婴儿、儿童和产妇死亡率的不利健康后果有关的短生育间隔也增加了母亲及其子女生存的机会。目的:评估也门哈德拉穆省穆卡拉地区育龄妇女生育空间的决定因素和知识。患者和方法:在穆卡拉区初级卫生保健中心对384名倍增年龄(15-49岁)妇女进行了横断面研究。该研究于2018年11月至2019年10月进行。结果:中位生育间隔为35个月。(50.8%)受访者的生育间隔低于理想生育间隔的认可间隔。多因素logistic V回归分析显示:母亲年龄在15 ~ 24岁之间(OR 3.255, 95%CI 1.598 ~ 6.629, P=0.001)、家庭收入不足(OR 1.867, 95%CI1.104 ~ 3.158, P= 0.020)、活产子女数≤3名(OR 1.225, 95%CI .532 ~ 2.520, P=0.027)、母乳喂养持续时间和时间;6个月(or 7.435,95%CI 1.490 ~ 37.101,P=0.014)或6 ~ 12个月(or 7.320, 95%CI 1.406 ~ 38.116, P=0.018)与短生育间隔风险增加有关,而母亲慢性疾病史(or .026,95%CI .003 ~ .227,P=.001)和现代计划生育方法的使用(or .208, 95%CI.112 ~)与短生育间隔风险增加有关。386, P=0.000)与生育空间小的风险降低有关。(58.1%)受访者对生育间隔有较高的认识。结论:某些因素是穆卡拉妇女生育间隔短的重要预测因素。这将鼓励延长生育间隔。关键词:生育间隔;knowledgment;初级保健中心;也门
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引用次数: 0
Resistant Dermatophytosis, the Causative Species, and Treatment 抗性皮肤植物病,致病物种和治疗
Pub Date : 2023-06-30 DOI: 10.26505/djm.24027091113
Shahad Khudhair Khalaf, Anaam Fuad Hussain, Khudhair Khalaf Al-Kayalli, Amenah Khudhair Khalaf
Background: Dermatophytosis was a fungal infection caused by molds (dermatophytes). Dermatophytes are a group of closely related filamentous fungi able to damage and utilize keratin found in the skin, hair, and nails. The present study aimed to isolate the species which cause resistant dermatophytosis, and clinical types of tinea, as well as to assess the response to different antifungal therapies. Patients and materials: ninety-two patients with different clinical types of tinea infections (ringworm) were seen in a private clinic in Baquba city for the period from May 2021 to December 2021, they were (42) females and (50) males, their ages ranged from (7-70) years with a mean age of (27.57±8) years. All patients were diagnosed clinically as ringworm and supported by isolation of the species from samples either by direct examination of samples or cultures on Sabouraud media, and the patients were treated by combination therapy of systemic and topical terbinafine and systemic azole (itraconazole capsules) for (1-3) months. Results: All patients complained of widespread and concomitant tinea. The most common causative dermatophytes species were Epidermopyton floccosum (41%) and Trichophyton rubrum (21%), less commonly Microsporum audouinii (9%), and the others as in table (1). The most common clinical type was tinea pedis (27%) then tinea cruris (24%), tinea corporis (21%), and tinea ungum (19%) as in table (2). All patients were cured on combination therapy of systemic (terbinafine and itraconazole) and topical (terbinafine). Five patients (5%) showed relapses of disease after discontinuation of therapy and retreated by the same method. Conclusion: Epidermophyton floccosum and Trichophyton rubrum were the most common cause of resistant tinea. Terbinafine and itraconazole were good therapeutic options for the treatment of resistant tinea. Key words: Tinea, Dermatophytes, Terbinafine, Itracanazole.
背景:皮肤真菌病是一种由霉菌引起的真菌感染。皮肤真菌是一组密切相关的丝状真菌,能够破坏和利用皮肤、头发和指甲中的角蛋白。本研究旨在分离引起耐药皮肤真菌病的物种和癣的临床类型,并评估对不同抗真菌治疗的反应。患者与资料:于2021年5月至2021年12月在巴古巴市某私人诊所共发现92例不同临床类型的癣感染(癣)患者,其中女性42例,男性50例,年龄7 ~ 70岁,平均年龄(27.57±8)岁。所有患者均被临床诊断为癣,并通过直接检查样品或Sabouraud培养基培养从样品中分离出癣种,患者接受全身和外用特比萘芬和全身唑(伊曲康唑胶囊)联合治疗(1-3个月)。结果:所有患者均有广泛并发的癣。最常见的致病菌种类是絮状表皮菌(41%)和红毛癣菌(21%),较少见的是奥杜氏小孢子菌(9%),其他见表(1)。最常见的临床类型是足癣(27%),其次是斑癣(24%)、体癣(21%)和不牙龈癣(19%),见表(2)。所有患者均经全身(特比萘芬和伊曲康唑)和局部(特比萘芬)联合治疗治愈。5例(5%)患者停药后复发,经相同方法治疗。结论:絮状表皮菌和红毛癣菌是引起耐药癣最常见的病原菌。特比萘芬和伊曲康唑是治疗耐药癣的良好选择。关键词:癣,皮癣菌,特比萘芬,伊曲康唑
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引用次数: 0
Precision of Proximal Segment Repositioning Using Digitally Planned Custom Made guide in Sagittal Split Ramus Osteotomy 矢状分叉支截骨术中数字规划自定义导具近段重新定位的精度研究
Pub Date : 2023-06-30 DOI: 10.26505/djm.v24i2.997
Banu Adil Mustafa,, Suha N Aloosi
Background: Orthognathic surgery is widely used surgical procedure. The most common used orthognathic surgical procedure is bilateral sagittal split osteotomy (BSSO) that is used for managing skeletal mandibular excess, deficiency or asymmetry. Objective: To   correct functional and aesthetic problems. Patients and Methods: A total of (12 patients) 24 condyles have been included in our study all with cl II malocclusion, open bites and asymmetry, both genders males and females, their age ranges between18 to 40 years, all the cases had preoperative and postoperative CT scans. Results: By comparing pre and post operative CT scans regarding condylar positions for both groups. The results revealed that there was less movement of condylar head in group with device and direction of movement was more favorable. Conclusion: This study showed that the Digitally Planned Custom Made guide was useful in repositioning condyles with minimal movement post operatively and more favorable direction of movement.
背景:正颌手术是广泛应用的外科手术。最常用的正颌外科手术是双侧矢状劈开截骨术(BSSO),用于治疗下颌骨过多、不足或不对称。目的:纠正功能和美学问题。患者与方法:本研究共纳入12例24个髁,均为cl - II型错颌合、开咬、不对称,男女均可,年龄18 ~ 40岁,所有病例术前、术后均行CT扫描。结果:通过比较两组患者手术前后髁突位置的CT扫描。结果显示,带器械组髁头运动较少,运动方向更有利。结论:本研究表明数字计划定制指南可用于髁突复位,术后运动最小,运动方向更有利。
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引用次数: 0
The Health risks caused by heavy metals contamination of milk products 乳制品重金属污染对健康的危害
Pub Date : 2023-06-30 DOI: 10.26505/djm.v24i2.1008
Moutaz A W Abdul Mounam
Background: Nowadays, a lot of food products are produced in large quantities in factories. Milk and its derivatives are among the most important and well-known things that may be mentioned. Due to the industrialization of many nations, heavy metals are regarded as the most significant contaminants and have an impact on the presence of these substances in milk and dairy products. The toxicity of different heavy metals on human health, as well as their sources in milk and other dairy products are all represented in the current review paper, which focuses on methodologies and regulatory constraints for heavy metals in milk. The study also examines the frequency of heavy metals detected in milk samples from Iraq, a few other nations in Asia, South America, the United States, and Africa, as well as a few instances from Europe. strategies to lessen the number of heavy metals in milk and its products or stop them from contaminating such foods. Conclusion: Heavy metals have several health risks. Heavy metal exposure is especially prevalent in young age and the elderly due to milk drinking. Due to rapid industrialization and urbanization, law enforcement, and less restrictions, developing countries have high heavy metal levels in milk. Wealthy countries have less heavy metal pollution. Milk samples had significant lead and cadmium levels, requiring strict environmental and health protections.
背景:如今,很多食品都是在工厂里大批量生产的。牛奶及其衍生物是可能提到的最重要和最广为人知的东西之一。由于许多国家的工业化,重金属被认为是最重要的污染物,并对牛奶和乳制品中这些物质的存在产生影响。不同重金属对人类健康的毒性,以及它们在牛奶和其他乳制品中的来源都在当前的审查文件中有所介绍,该文件侧重于牛奶中重金属的方法和监管限制。该研究还检查了来自伊拉克、亚洲、南美、美国和非洲的其他一些国家以及欧洲的牛奶样本中重金属的检测频率。减少牛奶及其产品中重金属含量或阻止其污染此类食品的策略。结论:重金属具有多种健康风险。由于喝牛奶,重金属暴露在年轻人和老年人中尤为普遍。由于快速的工业化和城市化、执法和较少的限制,发展中国家的牛奶中重金属含量很高。富裕国家的重金属污染较少。牛奶样品中含有大量的铅和镉,需要严格的环境和健康保护。
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引用次数: 0
Neurodermatitis in Baquba City, Diyala Governorate/Iraq Clinical and histopathological study 伊拉克迪亚拉省巴古拜市神经性皮炎的临床和组织病理学研究
Pub Date : 2023-06-30 DOI: 10.26505/djm.24026730721
Gibran Khalil Ibrahim, Sarmad Yahya abbood, Saad D Hameed
Background: Many patients that have itchy thickened skin lesions are lichenified, it's located on the extremities namely on the knees, feet, dorsum of the hands, and /or elbows was being seen bilaterally and may be symmetrically. Objective: To evaluate clinical and histopathological features of neurodermatitis with some similarities to psoriasis in Iraqi patients. Patients and Methods: Twenty- Five patients with neurodermatitis attending Department of Dermatology, Baquba Teaching Hospital were enrolled in this study in time between 1st January 2020 to 31th January 2021. All patients were being examined and full history was taken, including age of the patients, onset and duration of the disease, severity and type of itching. A full examination was done to identify the character, colour, shape, site, and involvement of other body site of lesion. Incisional biopsy specimens from both lesion and adjacent normal skin were obtained from 9 patients and submitted to histological assessment. Results: Ten of the patients (40%) were male and fifteen (60%) were females, their age ranged from 29-70 years, with a mean of 49.5 years. The average duration ranged from one month- 15 years with median 7.5 years. Clinically; patients have severe itchy plaques that distributed bilaterally like those of psoriasis, involvement of the knees (56%), dorsum of the both hands, feet, and elbows, also having ( lichenification ,that is characterized by thickening of the skin and exaggeration of the skin lines ) which characteristic of the individual lesion of lichen simplex chronicus, these plaques were symmetrical, well defined, sharper, more keratotic, violaceous pigmentation, marked accentuation and thickening of skin. Psoriatic scales are not present typically on the plaques of these patients. These plaques mainly located on extremities. Nine specimens' taken for histopathologiacl findings showed hyperkeratosis, acanthosis, dermal papilomatosis, suprapapillary epidermal thinning. All patients mentioned a severe itching which was paroxysmal in typing, more severe in the evening. Conclusion: ( Lichenified psoriasis) Psoriatic neurodermatitis might be lichen simplex chronicus as a result to repetitive itching and scratching of plaque psoriasis. This was typical neurodermatitis and not psoriasis. Keywords: Psoriatic neurodrmatitis,Lichenification, Plaque psoriasis
背景:许多有发痒增厚皮肤病变的患者都是地衣化的,它位于四肢,即膝盖、脚、手背和/或肘部,双侧可见,可能是对称的。目的:探讨伊拉克神经性皮炎与银屑病的临床及组织病理学特征。患者与方法:选取2020年1月1日至2021年1月31日在巴曲坝教学医院皮肤科就诊的神经性皮炎患者25例。对所有患者进行检查并记录全部病史,包括患者的年龄、发病和病程、瘙痒的严重程度和类型。进行全面检查以确定病变的特征、颜色、形状、部位和是否累及其他身体部位。9例患者均取病变及邻近正常皮肤的切口活检标本,并提交组织学评估。结果:男性10例(40%),女性15例(60%),年龄29 ~ 70岁,平均49.5岁。平均持续时间为1个月至15年,中位数为7.5年。临床;患者有严重的瘙痒斑块,像牛皮癣一样分布在双侧,累及膝盖(56%),双手,双脚和肘部,也有(地衣化,以皮肤增厚和皮肤线条夸张为特征),这是慢性单纯性地衣单个病变的特征,这些斑块对称,轮廓清晰,更尖锐,角化,色素沉着,皮肤明显加重和增厚。这些患者的斑块上通常没有银屑病鳞片。这些斑块主要位于四肢。9例标本经组织病理学检查发现角化过度、棘层增生、真皮乳头状瘤病、乳头上表皮变薄。所有患者均有严重的瘙痒,分型时为阵发性,晚上更严重。结论:银屑病神经性皮炎可能为慢性单纯性地衣,是银屑病斑块反复瘙痒和抓挠的结果。这是典型的神经性皮炎,而不是牛皮癣。关键词:银屑病神经皮炎,地衣化,斑块性银屑病
{"title":"Neurodermatitis in Baquba City, Diyala Governorate/Iraq Clinical and histopathological study","authors":"Gibran Khalil Ibrahim, Sarmad Yahya abbood, Saad D Hameed","doi":"10.26505/djm.24026730721","DOIUrl":"https://doi.org/10.26505/djm.24026730721","url":null,"abstract":"Background: Many patients that have itchy thickened skin lesions are lichenified, it's located on the extremities namely on the knees, feet, dorsum of the hands, and /or elbows was being seen bilaterally and may be symmetrically. Objective: To evaluate clinical and histopathological features of neurodermatitis with some similarities to psoriasis in Iraqi patients. Patients and Methods: Twenty- Five patients with neurodermatitis attending Department of Dermatology, Baquba Teaching Hospital were enrolled in this study in time between 1st January 2020 to 31th January 2021. All patients were being examined and full history was taken, including age of the patients, onset and duration of the disease, severity and type of itching. A full examination was done to identify the character, colour, shape, site, and involvement of other body site of lesion. Incisional biopsy specimens from both lesion and adjacent normal skin were obtained from 9 patients and submitted to histological assessment. Results: Ten of the patients (40%) were male and fifteen (60%) were females, their age ranged from 29-70 years, with a mean of 49.5 years. The average duration ranged from one month- 15 years with median 7.5 years. Clinically; patients have severe itchy plaques that distributed bilaterally like those of psoriasis, involvement of the knees (56%), dorsum of the both hands, feet, and elbows, also having ( lichenification ,that is characterized by thickening of the skin and exaggeration of the skin lines ) which characteristic of the individual lesion of lichen simplex chronicus, these plaques were symmetrical, well defined, sharper, more keratotic, violaceous pigmentation, marked accentuation and thickening of skin. Psoriatic scales are not present typically on the plaques of these patients. These plaques mainly located on extremities. Nine specimens' taken for histopathologiacl findings showed hyperkeratosis, acanthosis, dermal papilomatosis, suprapapillary epidermal thinning. All patients mentioned a severe itching which was paroxysmal in typing, more severe in the evening. Conclusion: ( Lichenified psoriasis) Psoriatic neurodermatitis might be lichen simplex chronicus as a result to repetitive itching and scratching of plaque psoriasis. This was typical neurodermatitis and not psoriasis. Keywords: Psoriatic neurodrmatitis,Lichenification, Plaque psoriasis","PeriodicalId":11202,"journal":{"name":"Diyala Journal of Medicine","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136255267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome of Post Induction Therapy for Acute Myeloid Leukemia in Nanakaly Hospital-Erbil 纳纳卡利埃尔比勒医院急性髓系白血病诱导治疗后疗效观察
Pub Date : 2023-06-30 DOI: 10.26505/djm.v24i2.1003
Ashqi Mohammed Kareem,, Nawsherwan Sadiq Mohammad
Background: Acute myeloid leukaemia in adult constitutes 80% of whole acute leukaemia cases; its frequency progressively increases with age. Objective: To evaluation the parameters of AML patients clinically and haematologically in Erbil City. Patients and Methods: A particular analysis of hospital records retrospective study of 29 patients with AML was taken on. The cases were analyzed and achieved at Nanakaly hospital in Erbil city during the years 20021-2022. Diagnosis was established on peripheral blood and bone marrow reports. The myeloid origin confirmation was concerned by cytochemistry, morphological subtyping was concerned according to the (FAB) criteria, biochemical tests, and cluster CDs was done by flowcytometery. Microsoft excel version 2010 and (GraphPad Prism 9.0.) was in employment for carrying out statistical analysis. Results: This study included 18 males and 11 females. Their ages ranged from 5 and 80 years with a mean age of 38.4 years. CD13 and CD33 are most expressed CD markers (75% and 70% respectively). CD22 and TdT lowest expressed CDs (10% and 5% respectively). Depending on the complete remission/Partial remission association, the p-value of platelets was significant (0.0207), CD64 and CD117 showed greater significant (<0.0001, <0.0001 respectively), BM hypercellularity fragments (P=0.0068), trials (P<0.0001), and blast percentage (P=0.0365). Conclusion: CDs and BM results are essential tools in the identification of AML. CD13 and CD33 are the most frequent CDs in this study. Morphologic valuation of BM was statistically significant, cellularity of BM and blast percentage was significantly correlated with post induction response in patients with AML.
背景:成人急性髓性白血病占全部急性白血病病例的80%;它的频率随着年龄的增长而逐渐增加。目的:了解埃尔比勒市AML患者的临床及血液学指标。患者与方法:对29例急性髓性白血病患者的住院记录进行回顾性分析。对埃尔比勒市纳纳卡利医院2002 -2022年期间的病例进行了分析和实现。诊断依据外周血和骨髓报告。细胞化学证实髓系起源,根据(FAB)标准进行形态学分型,生化试验,流式细胞术进行簇cd。使用Microsoft excel version 2010和GraphPad Prism 9.0进行统计分析。结果:本研究纳入男性18人,女性11人。年龄从5岁到80岁不等,平均年龄38.4岁。CD13和CD33是表达最多的CD标记物(分别为75%和70%)。CD22和TdT表达CDs最低(分别为10%和5%)。根据完全缓解/部分缓解相关性,血小板P值显著(0.0207),CD64和CD117更显著(分别<0.0001,<0.0001),BM高细胞片段(P=0.0068),试验(P<0.0001)和blast百分比(P=0.0365)。结论:cd和BM结果是鉴别AML的重要工具。CD13和CD33是本研究中最常见的cd。骨髓基质的形态学评估具有统计学意义,骨髓基质的细胞数量和细胞百分比与AML患者诱导后反应显著相关。
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引用次数: 1
Risk Factors for Colonization with S.aureus and Methicillin Resistant Staphylococcus aureus Among Health Care Workers in Al-Batool teaching hospital for maternity and children in Diyala, Iraq 伊拉克迪亚拉Al-Batool妇幼教学医院医护人员金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌定植的危险因素
Pub Date : 2023-06-30 DOI: 10.26505/djm.24026850816
Mohamed Mahjoob Aljboori, Rideh Abbas Abdul Jabbar, Ali Ibrahim Ali Al-Ezzy
Background: Staphylococcus aureus coloniza-tion for the human nose representing a challenge that requires a cope with host defense and competing resident microor-ganisms. Objective: To evaluate the risk factors for in-fection with S. au-reus and MRSA among health care workers (HCWs) in Al-Batool teaching hospital for maternity and children in Diyala, Iraq. Patients and Methods: A total of 27 swabs were taken from HCWs in Al-Batool teaching hospital for ma-ternity and chil-dren in Diyala, Iraq (ATHMC) Standard microbi-ological proce-dures were used for diagnosis of S. aureus and Methicillin Re-sistant Staphylo-coccus aureus (MRSA). Results: Significant corre-lation was report-ed between age and colonization with S. aureus & MRSA. Inverse correlation was reported between education level and colonization with S. aureus and MRSA. Signifi-cant correlation was reported be-tween acne and colonization with S. aureus. Signifi-cant correlation was reported be-tween sinusitis, years of experi-ence, contact with farm animals and colonization with S. aureus and MRSA. Significant correlation was reported between ward of duty and colonization with MRSA. Conclusion: Colonization with S. aureus and MRSA inversely correlated with younger age group, education level of HCWs. Colonization with S. aureus and MRSA correlated with sinusitis, years of experience (5 -6); contact with farm animals. Colonization with S. aureus correlated with acne. Colonization with MRSA correlated with ward of duty at children care floor. Keywords: Health care workers , S.aureus, MRSA ,Risk factors
背景:金黄色葡萄球菌在人鼻子的定殖是一种挑战,需要应对宿主防御和竞争的常驻微生物。目的:了解伊拉克迪亚拉Al-Batool妇幼教学医院医护人员感染金黄色葡萄球菌和MRSA的危险因素。患者和方法:从伊拉克迪亚拉Al-Batool妇幼教学医院(ATHMC)的卫生保健人员中采集27份拭子,采用标准微生物学程序诊断金黄色葡萄球菌和耐甲氧西林金黄色葡萄球菌(MRSA)。结果:年龄与金黄色葡萄球菌定植有显著相关性;耐甲氧西林金黄色葡萄球菌。据报道,受教育程度与金黄色葡萄球菌和MRSA定植呈负相关。据报道,痤疮与金黄色葡萄球菌定植之间存在显著相关性。据报道,鼻窦炎、经验年限、与农场动物接触与金黄色葡萄球菌和MRSA定植之间存在显著相关性。据报道,值班病房与MRSA定植之间存在显著相关性。结论:金黄色葡萄球菌和MRSA的定殖与年龄、文化程度呈负相关。金黄色葡萄球菌和MRSA定植与鼻窦炎相关,年数(5 -6);与农场动物接触。金黄色葡萄球菌的定植与痤疮相关。耐甲氧西林金黄色葡萄球菌的定植与儿童看护楼层的值勤相关。关键词:医护人员,金黄色葡萄球菌,MRSA,危险因素
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引用次数: 0
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Diyala Journal of Medicine
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