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Molecular prevalence of MecA and Blaz Genes with phenotypic analysis of Antibiotic Sensitivity Pattern for S.aureus Isolated From Dermal lesions of Sheep Breeders In Diyala Governorate – Iraq MecA和Blaz基因在伊拉克迪亚拉省绵羊养殖者皮肤病变中分离的金黄色葡萄球菌的分子流行及抗生素敏感性表型分析
Pub Date : 2023-10-31 DOI: 10.26505/djm.v25i1.1016
Zainab Bressam Fajer, Ali Ibrahim Ali Al-Ezzy, Ahmed H. AL-Zuhairi
Background: S. aureus is one of the dominant bacterial pathogens among dermal infections in human and animals, which have resistance to different antimicrobial drugs. Objective: Isolation and identification of S.aureus from skin lesions among sheep breeders by traditional methods, Vitek 2 system and PCR using Staur 4, 6 specific pri-mers for validation, Detection of genes (methicillin resistant (mecA), Beta- lac-tamase gene (blaZ) by conventional PCR ,determine antibiotic sensitivity pat-tern by kirby bauer disc diffusion method. Patients and Methods: A total of 44 swaps were collected from sheep breeders suffered from variety of infected skin lesions to detect methicillin sensitive and resistant s. aureus by employing traditional methods in addition to confirmatory techniques through fast rapid VETEK2 system , detection of genes (methicillin resistant (mecA), Be-ta- lactamase gene (blaZ) by conventional PCR , and determine antibiotic sensi-tivity pattern by kirby bauer disc diffusion method. Results: S.aureus was isolated from 15/44,( 34.09%) of skin lesion of sheep breeders . A total of 6/15 ,(40%) were methicillin resistant S.aureus (MRSA) ,which represent ( 13.63%) from total samples .Beta lactamase gene primers was detected in all S.aureus isolates. A 6/15,(40%) of S.aureus have resistance for members of antibiotics classes, penicillins, polypeptides, fluoroquinolones, macrolide which include the following : methicillin that was confirmed early by detection of me-cA gene , levofloxacin , ofloxacin , erythromycin and vancomycin. A 6/15,(40%) of S.aureus have multidrug resistant trait for Penicillins, Polypep-tides, Fluoroquinolones, Macrolide antibiotics. Non multidrug resistant S.aureus was reported for Penicillins (oxacillin,4/15, 26%) and Polypeptides antibiotics (vancomycin 8/15, 53.33%) of S.aureus . Absolute sensitivity was reported for gentamycin, tetracycline, rifampicin, imipenem and chloramphenicol. Conclusion: Methicillin sensitive S.aureus was more common compared with MRSA isolated from dermal infections of sheep breeders. Blaz gene was predominantly ex-pressed by S.aureus isolates followed by Mec A gene. S.aureus have resistance for penicillins, polypeptides, fluoroquinolones, macrolide which include the fol-lowing : methicillin, levofloxacin , ofloxacin , erythromycin and vancomycin . S.aureus have multidrug resistant trait for Penicillins, Polypeptides, Fluoroquin-olones, Macrolide antibiotics. S.aureus was absolutely sensitive to gentamycin, tetracycline, rifampicin, imipenem and chloramphenicol.
背景:金黄色葡萄球菌(S. aureus)是人畜皮肤感染的主要病原菌之一,对多种抗菌药物具有耐药性。 目的:采用传统方法、Vitek 2系统和Staur 4、6特异性引物对金黄色葡萄球菌进行分离鉴定,采用常规PCR方法检测耐甲氧西林(mecA)、β -内酰胺酶基因(blaZ),采用kirby bauer盘扩散法测定抗生素敏感型;患者和方法:收集各种皮损感染的绵羊养殖户共44只交换品,除采用快速快速VETEK2系统检测甲氧西林敏感和耐药金黄色葡萄球菌外,采用传统方法检测,采用常规PCR检测基因(甲氧西林耐药基因(mecA)、Be-ta-内酰胺酶基因(blaZ),采用kirby bauer盘扩散法检测抗生素敏感型;结果:从绵羊养殖者皮肤损伤中分离出金黄色葡萄球菌15/44,占34.09%。耐甲氧西林金黄色葡萄球菌(MRSA)共6/15(40%),占总样本的13.63%。所有金黄色葡萄球菌分离株均检测到β -内酰胺酶基因引物。6/15(40%)的金黄色葡萄球菌对抗生素类成员、青霉素类、多肽类、氟喹诺酮类、大环内酯类耐药,其中包括:通过me-cA基因检测早期确认的甲氧西林、左氧氟沙星、氧氟沙星、红霉素和万古霉素。6/15(40%)金黄色葡萄球菌对青霉素类、多肽类、氟喹诺酮类、大环内酯类抗生素具有多重耐药特征。金黄色葡萄球菌中青霉素类(4/15,26%)和多肽类抗生素(万古霉素8/15,53.33%)检出非耐多药金黄色葡萄球菌。庆大霉素、四环素、利福平、亚胺培南和氯霉素均有绝对敏感性。 结论:对甲氧西林敏感的金黄色葡萄球菌比从绵羊养殖户皮肤感染中分离的MRSA更为常见。金黄色葡萄球菌主要表达Blaz基因,其次是Mec A基因。金黄色葡萄球菌对青霉素、多肽、氟喹诺酮类药物、大环内酯类药物有耐药性,其中包括:甲氧西林、左氧氟沙星、氧氟沙星、红霉素和万古霉素。金黄色葡萄球菌对青霉素类、多肽类、氟喹酮类、大环内酯类抗生素具有多重耐药特征。金黄色葡萄球菌对庆大霉素、四环素、利福平、亚胺培南和氯霉素绝对敏感。
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 Objective: Isolation and identification of S.aureus from skin lesions among sheep breeders by traditional methods, Vitek 2 system and PCR using Staur 4, 6 specific pri-mers for validation, Detection of genes (methicillin resistant (mecA), Beta- lac-tamase gene (blaZ) by conventional PCR ,determine antibiotic sensitivity pat-tern by kirby bauer disc diffusion method.
 Patients and Methods: A total of 44 swaps were collected from sheep breeders suffered from variety of infected skin lesions to detect methicillin sensitive and resistant s. aureus by employing traditional methods in addition to confirmatory techniques through fast rapid VETEK2 system , detection of genes (methicillin resistant (mecA), Be-ta- lactamase gene (blaZ) by conventional PCR , and determine antibiotic sensi-tivity pattern by kirby bauer disc diffusion method.
 Results: S.aureus was isolated from 15/44,( 34.09%) of skin lesion of sheep breeders . A total of 6/15 ,(40%) were methicillin resistant S.aureus (MRSA) ,which represent ( 13.63%) from total samples .Beta lactamase gene primers was detected in all S.aureus isolates. A 6/15,(40%) of S.aureus have resistance for members of antibiotics classes, penicillins, polypeptides, fluoroquinolones, macrolide which include the following : methicillin that was confirmed early by detection of me-cA gene , levofloxacin , ofloxacin , erythromycin and vancomycin. A 6/15,(40%) of S.aureus have multidrug resistant trait for Penicillins, Polypep-tides, Fluoroquinolones, Macrolide antibiotics. Non multidrug resistant S.aureus was reported for Penicillins (oxacillin,4/15, 26%) and Polypeptides antibiotics (vancomycin 8/15, 53.33%) of S.aureus . Absolute sensitivity was reported for gentamycin, tetracycline, rifampicin, imipenem and chloramphenicol.
 Conclusion: Methicillin sensitive S.aureus was more common compared with MRSA isolated from dermal infections of sheep breeders. Blaz gene was predominantly ex-pressed by S.aureus isolates followed by Mec A gene. S.aureus have resistance for penicillins, polypeptides, fluoroquinolones, macrolide which include the fol-lowing : methicillin, levofloxacin , ofloxacin , erythromycin and vancomycin . S.aureus have multidrug resistant trait for Penicillins, Polypeptides, Fluoroquin-olones, Macrolide antibiotics. S.aureus was absolutely sensitive to gentamycin, tetracycline, rifampicin, imipenem and chloramphenicol.","PeriodicalId":11202,"journal":{"name":"Diyala Journal of Medicine","volume":"43 3","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135870560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Tantalum Oxide Nanopowder on Heat Cure Acrylic Resin Impact Strength and Surface Hardness 纳米氧化钽粉对热固化丙烯酸树脂冲击强度和表面硬度的影响
Pub Date : 2023-10-31 DOI: 10.26505/djm.v25i1.1030
Sajjad yaqoub yousif ,, Zainab Saleh Abdullah
Background: In elderly patients, fracture of the denture is one of the most common problems. Therefore, in this research, a chemical tantalum oxide was added to test its effect on the extent of increasing the strength of the denture and its ability to withstand fracture. Objective: To assess how Tantalum oxide affected heat – cured acrylic s impact strength and hardness. Patients and Methods: The Intention was to create a total of (60) specimens. Twenty samples were made without additives (control), and 40 had made with tantalum oxide at two different amounts ( 1%, 1.5%). Results: The impact strength tests showed highly significant difference among studied groups . The hardness test also showed really significant difference between the two groups, the controls and the experiments. when tantalum oxide had added the impact strength and hardness had increase in all concentration. Conclusion: Denture fracture in elderly patients is the main problem, while when adding this substance, a decrease in the fracture rate was observed when compared with dentures without adding this substance.
背景:在老年患者中,义齿骨折是最常见的问题之一。因此,在本研究中,加入化学氧化钽,测试其对义齿强度增加程度和抗断裂能力的影响。 目的:探讨氧化钽对热固化丙烯酸树脂冲击强度和硬度的影响;患者和方法:目的是创建共(60)个标本。20个样品不添加添加剂(对照),40个样品添加了两种不同量的氧化钽(1%,1.5%)。结果:各组间冲击强度试验差异显著。硬度测试也显示了两组,对照组和实验组之间的显著差异。添加氧化钽后,各浓度的冲击强度和硬度均有提高。 结论:老年患者义齿骨折是主要问题,添加该物质后,与未添加该物质的义齿相比,骨折率明显降低。 & # x0D;
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 Objective: To assess how Tantalum oxide affected heat – cured acrylic s impact strength and hardness.
 Patients and Methods: The Intention was to create a total of (60) specimens. Twenty samples were made without additives (control), and 40 had made with tantalum oxide at two different amounts ( 1%, 1.5%).
 Results: The impact strength tests showed highly significant difference among studied groups . The hardness test also showed really significant difference between the two groups, the controls and the experiments. when tantalum oxide had added the impact strength and hardness had increase in all concentration.
 Conclusion: Denture fracture in elderly patients is the main problem, while when adding this substance, a decrease in the fracture rate was observed when compared with dentures without adding this substance.
 
","PeriodicalId":11202,"journal":{"name":"Diyala Journal of Medicine","volume":"98 6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135872664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IL-17 and IL-10 as potential biomarkers for diagnosing periodontitis patients: A Review IL-17和IL-10作为诊断牙周炎患者的潜在生物标志物:综述
Pub Date : 2023-10-31 DOI: 10.26505/djm.v25i1.1025
Maha Abdulsalam Mohammed ,, Raghad Fadhil Abbas
Background:Evaluation methods for periodontal disorders are continually being refined to yield more precise, reliable, and time-efficient findings. Radiographic reports and clinical assessments of periodontal tissues, which served as the basis for earlier trends, were used to identify disorders affecting the tooth-supporting structures. As traditional approaches have become more apparent gradually over time, new methods emerged, some of which have been empirically validated. One example is the detection and measurement of biomarkers in bodily fluids. One of the most pressing issues in periodontal field nowadays is the search for an idealized periodontal diagnostic/prognostic biomarker that can both identify diseased areas and track the therapeutic success of periodontal treatment. Both IL-17 and IL-10 have shown connection to periodontitis that could encourage using them as diagnostic tools. Objective: To provide a review of the role and association of the above biomarkers to periodontitis. Patients and Methods: A systematic research of Google scholar, Scopus, PubMed Central, research gate was conducted using keywords such as diagnosis, periodontitis, IL-17, IL-10, biomarkers, Saliva and gingival crevicular fluid (GCF). Results: out of 58 records which resulted from the initial search only 14 were included which used roles, associations, and diagnosis as their outcomes. Conclusion: Evidence from the selected records suggests that the above stated biomarkers might be able to discriminate periodontitis from health, monitoring disease progression and post treatment outcome, but actual clinical application needs much further research.
背景:牙周疾病的评估方法正在不断完善,以产生更精确、可靠和高效的结果。放射学报告和牙周组织的临床评估,作为早期趋势的基础,被用来确定影响牙齿支撑结构的疾病。随着时间的推移,传统方法逐渐变得更加明显,新的方法出现了,其中一些已经得到了经验验证。体液中生物标记物的检测和测量就是一个例子。目前牙周领域最紧迫的问题之一是寻找一种理想的牙周诊断/预后生物标志物,既能识别病变区域,又能跟踪牙周治疗的治疗成功。IL-17和IL-10都显示出与牙周炎的联系,可以鼓励将它们作为诊断工具。目的:综述上述生物标志物在牙周炎中的作用及相关性。患者与方法:以诊断、牙周炎、IL-17、IL-10、生物标志物、唾液、龈沟液(GCF)等关键词对Google scholar、Scopus、PubMed Central、research gate进行系统研究。 结果:在最初搜索的58条记录中,只有14条记录使用角色、关联和诊断作为结果。 结论:所选记录的证据表明,上述生物标志物可能能够区分牙周炎与健康,监测疾病进展和治疗后结果,但实际临床应用需要进一步研究。
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 Objective: To provide a review of the role and association of the above biomarkers to periodontitis.
 Patients and Methods: A systematic research of Google scholar, Scopus, PubMed Central, research gate was conducted using keywords such as diagnosis, periodontitis, IL-17, IL-10, biomarkers, Saliva and gingival crevicular fluid (GCF).
 Results: out of 58 records which resulted from the initial search only 14 were included which used roles, associations, and diagnosis as their outcomes.
 Conclusion: Evidence from the selected records suggests that the above stated biomarkers might be able to discriminate periodontitis from health, monitoring disease progression and post treatment outcome, but actual clinical application needs much further research.","PeriodicalId":11202,"journal":{"name":"Diyala Journal of Medicine","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135869906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Food poisoning outbreak in prisoners 囚犯食物中毒爆发
Pub Date : 2023-10-31 DOI: 10.26505/djm.v25i1.1028
Mazin Khalid Abdullah ,, Marwa Qader Salman ,, Ibraheem Mahmood Rajab
Background: An outbreak of food poisoning was investigated in a prison in AL-Muradia area in Diyala in June 23, after poisoning cases was reported to the primary health care center of the area on June 22, 2022. Objective: To determine the cause of food poisoning outbreak among the inmates. Patients and Methods: A retrospective cohort study was conducted in a prison in AL-Muradia area in Diyala in June 23 and the data has been collected using a questionnaire developed by the researcher and filled out by direct interview with all individuals who attended meals, all person in that prison were interviewed and traced back every meal served in the last two days before the investigation. Results: All people who had interviewed, (12) reported to have a common meal in afternoon of 21-June 2022, with age mean of 33.5+_ 6 SD. (5) of them met the probable case definition of food poisoning, and the first two cases had the onset of symptoms within 12hr. of the exposure, the last case experienced a symptom was after 24 hr., all cases had fever and headache followed by diarrhea (80%), nausea and abdominal pain (60%) and vomiting (40%). The meal items were canned meat, canned tuna, grilled chicken, apricot, plum and yogurt, the highest relative risk was for tuna (RR=4) with risk difference of (50%) Conclusion: The food item responsible for the outbreak was canned tuna. Based on the incubation period, symptoms and the unhealthy storage of food suggested that canned tuna could be contaminated with salmonella spp.
背景:在2022年6月22日向迪亚拉AL-Muradia地区的初级卫生保健中心报告中毒病例后,于6月23日在迪亚拉AL-Muradia地区的一所监狱调查了一起食物中毒事件。目的:了解某监狱服刑人员食物中毒暴发的原因。 患者和方法:于6月23日在迪亚拉AL-Muradia地区的一所监狱进行了一项回顾性队列研究,数据是通过研究人员开发的问卷收集的,并通过直接采访所有参加用餐的人来填写,该监狱的所有人都接受了采访,并追溯了调查前最后两天提供的每一顿饭。结果:所有受访者(12人)报告在2022年6月21日下午共吃过一顿饭,平均年龄为33.5+ 6sd。(5)例符合食物中毒的可能病例定义,且前2例均在12h内出现症状。在接触中,最后一例出现症状是在24小时之后。所有病例均以发热、头痛为主,其次为腹泻(80%)、恶心、腹痛(60%)和呕吐(40%)。肉类罐头、金枪鱼罐头、烤鸡罐头、杏子罐头、李子罐头和酸奶罐头,相对危险度最高的是金枪鱼罐头(RR=4),危险度差为50% 结论:引起此次疫情的食品为金枪鱼罐头。从潜伏期、症状和不健康的食品储存情况来看,金枪鱼罐头可能受到沙门氏菌的污染。
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 Objective: To determine the cause of food poisoning outbreak among the inmates.
 Patients and Methods: A retrospective cohort study was conducted in a prison in AL-Muradia area in Diyala in June 23 and the data has been collected using a questionnaire developed by the researcher and filled out by direct interview with all individuals who attended meals, all person in that prison were interviewed and traced back every meal served in the last two days before the investigation.
 Results: All people who had interviewed, (12) reported to have a common meal in afternoon of 21-June 2022, with age mean of 33.5+_ 6 SD. (5) of them met the probable case definition of food poisoning, and the first two cases had the onset of symptoms within 12hr. of the exposure, the last case experienced a symptom was after 24 hr., all cases had fever and headache followed by diarrhea (80%), nausea and abdominal pain (60%) and vomiting (40%). The meal items were canned meat, canned tuna, grilled chicken, apricot, plum and yogurt, the highest relative risk was for tuna (RR=4) with risk difference of (50%)
 Conclusion: The food item responsible for the outbreak was canned tuna. Based on the incubation period, symptoms and the unhealthy storage of food suggested that canned tuna could be contaminated with salmonella spp.","PeriodicalId":11202,"journal":{"name":"Diyala Journal of Medicine","volume":"30 2","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135871101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bocavirus and rotavirus co-infection in children with acute gastroenteritis and associated risk factors 急性胃肠炎患儿的bocavavirus和轮状病毒合并感染及其相关危险因素
Pub Date : 2023-10-31 DOI: 10.26505/djm.v25i1.1031
Mohammad Yaseen Mohammad,, Arwa Mujahid Al-Shuwaikh ,, Haider Talib Al-Hamdani
Background: Both Viruses are the leading cause of acute gastroenteritis in infants and young children and are considered an important cause of mortality worldwide. Objective: To estimate the rate of human bocavirus and rotavirus co-infection in children with acute gastroenteritis and determine any association with different risk factors. Patients and Methods: Stool samples were collected from one hundred children suffering from acute gastroenteritis at the Central Teaching Hospital of Pediatrics, Baghdad, Iraq, for the period from December 2021 to April 2022. Samples were stored at -20 °C until they were utilized by PCR and ELISA to identify the human bocavirus (HBoV) DNA and rotavirus antigen (RV-Ag), respectively. Results: This cross-sectional study showed that HBoV DNA was detected in 10 out of 100 samples (10%), while RV-Ag was detected in 22 out of 93 samples (23.66%), and the co-infection rate was 100% (All cases positive for HBoV were also positive for RV). None of the studied demographic data and risk factors showed a significant association with HBoV and/or rotavirus infection (P>0.05). Conclusion: Most NICU deaths resulted from prematurity and respiratory distress syndrome. Enhancing healthcare personnel skills, standardizing protocols, and evidence-based practices for preterm and respiratory distress syndrome management can help reduce neonatal mortality rates in Iraq.
背景:这两种病毒都是婴幼儿急性胃肠炎的主要原因,并且被认为是世界范围内死亡的重要原因。& # x0D;目的:了解小儿急性胃肠炎中人bocavavirus和轮状病毒合并感染的发生率,并探讨其与不同危险因素的关系。患者和方法:从2021年12月至2022年4月期间在伊拉克巴格达儿科中心教学医院收集了100名急性肠胃炎儿童的粪便样本。样品保存于-20°C,待用PCR和ELISA分别鉴定人bocavavirus (HBoV) DNA和轮状病毒抗原(RV-Ag)。 结果:横断面研究显示,100份样本中有10份检出HBoV DNA(10%), 93份样本中有22份检出RV- ag(23.66%),合并感染率为100%(所有HBoV阳性病例同时也检出RV)。所研究的人口统计学数据和危险因素均未显示与HBoV和/或轮状病毒感染有显著关联(P>0.05)。结论:新生儿重症监护病房死亡以早产和呼吸窘迫综合征为主。在早产儿和呼吸窘迫综合征管理方面,提高医护人员的技能、规范规程和循证做法有助于降低伊拉克的新生儿死亡率。
{"title":"Bocavirus and rotavirus co-infection in children with acute gastroenteritis and associated risk factors","authors":"Mohammad Yaseen Mohammad,, Arwa Mujahid Al-Shuwaikh ,, Haider Talib Al-Hamdani","doi":"10.26505/djm.v25i1.1031","DOIUrl":"https://doi.org/10.26505/djm.v25i1.1031","url":null,"abstract":"Background: Both Viruses are the leading cause of acute gastroenteritis in infants and young children and are considered an important cause of mortality worldwide. 
 Objective: To estimate the rate of human bocavirus and rotavirus co-infection in children with acute gastroenteritis and determine any association with different risk factors.
 Patients and Methods: Stool samples were collected from one hundred children suffering from acute gastroenteritis at the Central Teaching Hospital of Pediatrics, Baghdad, Iraq, for the period from December 2021 to April 2022. Samples were stored at -20 °C until they were utilized by PCR and ELISA to identify the human bocavirus (HBoV) DNA and rotavirus antigen (RV-Ag), respectively.
 Results: This cross-sectional study showed that HBoV DNA was detected in 10 out of 100 samples (10%), while RV-Ag was detected in 22 out of 93 samples (23.66%), and the co-infection rate was 100% (All cases positive for HBoV were also positive for RV). None of the studied demographic data and risk factors showed a significant association with HBoV and/or rotavirus infection (P>0.05).
 Conclusion: Most NICU deaths resulted from prematurity and respiratory distress syndrome. Enhancing healthcare personnel skills, standardizing protocols, and evidence-based practices for preterm and respiratory distress syndrome management can help reduce neonatal mortality rates in Iraq.","PeriodicalId":11202,"journal":{"name":"Diyala Journal of Medicine","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135871125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of magnetic resonance imaging technique in detection dentofacial pattern among Diyala Governorate population 磁共振成像技术在迪亚拉省人口牙面形态检测中的作用
Pub Date : 2023-10-31 DOI: 10.26505/djm.v25i1.1027
Ali Hakiem Tawfieq
Background: Magnetic Resonance Imaging is accepted as the most advanced imaging modality for diagnosis of maxillofacial soft tissue abnormalities. It is noninvasive and has the potential to yield high quality tomographic imaging in any plane with bone as well as soft tissue spatial resolution. Additionally, the patient is not exposed to ionizing radiation or any biological hazards. Objective: To determine the depth of masseter muscle in various vertical dentofacial shapes and to relate masseter muscle depth with craniofacial shapes using magnetic resonance imaging technique (MRI). Patients and Methods: Thirty youthful, healthy people overall between the ages of 16 and 40 were chosen and divided into three groups of ten, using (MRI), categorize each as a vertical, average, and horizontal grower. The concepts masseter muscles had their different anatomical dimensions sagittal, axial, and coronal directions utilizing MRI perspectives. Results: Our study found the difference is significant when comparing between the growth patterns in both direction (horizontal and vertical)(p<0.05), also the direction of muscle fibers of masseter muscle (anterior and posterior) away from first molar to the zygomatic arch was saved. In contrast to the horizontal list, when the fibers are attached anteriorly and vertically at the jaw angle, we discovered in our research that the direction of the muscle fibers is toward the posterior side more than anterior side and at a sharper angle. Conclusion: The study found that the muscle fibers in the extra posterior direction had a steeper angle than the horizontal group, with the vertical fiber orientation having an anterior connection at the angle of the mouth.
背景:磁共振成像被认为是诊断颌面部软组织异常的最先进的成像方式。它是非侵入性的,有潜力在任何平面上产生高质量的骨层析成像以及软组织空间分辨率。此外,患者没有暴露于电离辐射或任何生物危害。 目的:利用磁共振成像技术(MRI)测定不同垂直牙面形状的咬肌深度,并将咬肌深度与颅面形状联系起来。患者和方法:选择30名年龄在16岁至40岁之间的年轻健康人群,使用MRI将其分为三组,每组10人,将每组分为垂直、平均和水平生长。从MRI角度看,咬肌的概念在矢状、轴状和冠状方向上有不同的解剖尺寸。结果:我们的研究发现,在水平方向和垂直方向上的生长模式比较差异有显著性(p < 0.05),并且从第一磨牙到颧弓的咬肌肌纤维方向(前、后)被保留。与水平表相反,当纤维在颚角前垂直附着时,我们在研究中发现肌纤维的方向比朝向前侧更多地朝向后侧,并且角度更尖锐。 结论:研究发现,超后方向的肌纤维比水平方向的肌纤维角度更陡,垂直方向的肌纤维在口角处有前连接。
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引用次数: 0
Evaluating symptoms of chronic rhino sinusitis and most common sinuses affected 评估慢性犀牛鼻窦炎的症状和最常见的鼻窦受影响
Pub Date : 2023-10-31 DOI: 10.26505/djm.v25i1.1032
Qays Jaafar Khalaf
Background: Chronic rhinosinusitis is a common condition that significantly affect the quality of life, high health-care consumption and significant comorbidity. Objective: To investigate and identify the symptoms that are most often experienced by people with chronic rhinosinusitis. Patients and Methods: In this cross-sectional study, we conducted one hundred patients complaining of chronic rhinosinusitis presented to the outpatient clinic for otolaryngology at Baquba teaching hospital; the patients were chosen randomly. A careful clinical examination following comprehensive history taking done for all of the patients. All patient's main complaint were nasal airway obstruction, nasal discharge, and anosmia. In addition to a clinical evaluation, a computed tomography (CT) scan of the nose and paranasal sinuses was performed,. And Diagnostic nasal endoscopy Results: The population under investigation had a mean age of 35 years and was mostly comprised of males. The majority of patients in this study reported a common symptoms, including nasal congestion (72%), headache (68%), and rhinorrhea (mucus discharge) (58%) Conclusion: Chronic rhinosinusitis is characterised by a set of symptoms that, if caught early, may be diagnosed and treated effectively.
背景:慢性鼻窦炎是一种常见病,严重影响生活质量,医疗保健消费高,合并症显著。 目的:探讨慢性鼻窦炎患者最常见的症状。 患者与方法:在本横断面研究中,我们收集了100例在巴曲坝教学医院耳鼻喉科门诊主诉慢性鼻窦炎的患者;患者是随机选择的。在对所有患者进行全面的病史记录后进行仔细的临床检查。所有患者的主诉均为鼻气道梗阻、流鼻液和嗅觉丧失。除了临床评估外,还进行了鼻和鼻窦的计算机断层扫描(CT)。诊断性鼻内窥镜 结果:调查人群平均年龄35岁,以男性为主。本研究中大多数患者报告了常见症状,包括鼻塞(72%)、头痛(68%)和鼻漏(粘液排出)(58%) 结论:慢性鼻窦炎的特点是一系列症状,如果及早发现,可以有效地诊断和治疗。
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引用次数: 0
The correlation between tonsillectomy and Covid-19 infection 扁桃体切除术与Covid-19感染的相关性
Pub Date : 2023-10-31 DOI: 10.26505/djm.v25i1.1034
Hani Hameed Wadi ,, Ahmed Amer Hadi Al-Majmaie,, Anfal Shakir Motib
Background: The role of tonsillectomy history on the course of COVID-19 infection has not been determined, including COVID-19 colonization in the tonsillar tissue and reduce the cytokine activity of palatine tonsil tissue and the immune response of humoral with cellular immune. Objective: To determine the effect of tonsillectomy in the development of COVID-19 infection. Patients and Methods: It was collected 150 cases diagnosed with COVID-19 and they admitted to Diyala Hospitals. Data including age, gender, smokers, and symptom status were collected. Results: The total number of the patients who were positive COVID-19 was 150, the 102 (68%) of them were males and 48 (32 %) were females. It was found that the highest incidence rate was noticed among non-smoking patients (114 cases) compare to smokers (36 cases) (p<0.0001). It was appeared a significant difference (p<0.0001) of the symptoms of COVID-19 patients with tonsillectomy relative to the patients without tonsillectomy history. Conclusion: Patients that infected with COVID-19 and they have a history of tonsillectomy have more systemic response including fever, chills and other symptoms compare to the patients without tonsillectomy history.
背景:扁桃体切除术史对COVID-19感染过程的作用尚未确定,包括COVID-19在扁桃体组织中的定植和降低腭扁桃体组织的细胞因子活性以及体液与细胞免疫的免疫反应。 目的:探讨扁桃体切除术对COVID-19感染发展的影响。 患者和方法:收集在迪亚拉医院确诊的COVID-19患者150例。收集的数据包括年龄、性别、吸烟者和症状状态。 结果:新冠肺炎阳性患者150例,其中男性102例(68%),女性48例(32%)。非吸烟患者发病率最高(114例),吸烟患者发病率最高(36例)(p<0.0001)。扁桃体切除术后的COVID-19患者的症状与无扁桃体切除术史的患者相比有显著差异(p<0.0001)。 结论:与无扁桃体切除史的患者相比,感染COVID-19并有扁桃体切除史的患者有更多的全身反应,包括发烧、寒战等症状。
{"title":"The correlation between tonsillectomy and Covid-19 infection","authors":"Hani Hameed Wadi ,, Ahmed Amer Hadi Al-Majmaie,, Anfal Shakir Motib","doi":"10.26505/djm.v25i1.1034","DOIUrl":"https://doi.org/10.26505/djm.v25i1.1034","url":null,"abstract":"Background: The role of tonsillectomy history on the course of COVID-19 infection has not been determined, including COVID-19 colonization in the tonsillar tissue and reduce the cytokine activity of palatine tonsil tissue and the immune response of humoral with cellular immune.&#x0D; Objective: To determine the effect of tonsillectomy in the development of COVID-19 infection.&#x0D; Patients and Methods: It was collected 150 cases diagnosed with COVID-19 and they admitted to Diyala Hospitals. Data including age, gender, smokers, and symptom status were collected.&#x0D; Results: The total number of the patients who were positive COVID-19 was 150, the 102 (68%) of them were males and 48 (32 %) were females. It was found that the highest incidence rate was noticed among non-smoking patients (114 cases) compare to smokers (36 cases) (p<0.0001). It was appeared a significant difference (p<0.0001) of the symptoms of COVID-19 patients with tonsillectomy relative to the patients without tonsillectomy history.&#x0D; Conclusion: Patients that infected with COVID-19 and they have a history of tonsillectomy have more systemic response including fever, chills and other symptoms compare to the patients without tonsillectomy history.","PeriodicalId":11202,"journal":{"name":"Diyala Journal of Medicine","volume":"152 ","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135872043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Contributors to the neonate’s death in the intensive care unit 新生儿在重症监护室死亡的原因
Pub Date : 2023-10-31 DOI: 10.26505/djm.v25i1.1035
Ahmed Mustafa Kamal ,, Khalid Zuhair Naama ,, Hossam Subhi Talab
Background: Iraq had the third-greatest neonatal mortality rate in the Middle East in 2021 with 14 fatalities per 1,000 live births. Objective: To investigate factors contributing to poor outcomes in the neonatal intensive care unit. Patients and Methods: A retrospective cohort study conducted between 1 April to 31 September 2022 involved 632 neonates. Required data and outcomes were collected using predesigned forms. Results: The mortality rate in NICU was 23.9%, with 64.9% of deaths occurring within the first six days. The overall mortality rate was 38.5 per 1000 live births. Deceased neonates had significantly lower gestational age and birth weight (P<0.001). Prematurity, respiratory distress syndrome, and congenital anomalies contributed to 94%, 73.5%, and 20.5% of deaths respectively. Mortality was significantly higher in patients with RDS 111(56.3%; P<0.001), pulmonary hemorrhage nine (100%; P<0.001), sepsis 26 (74.3%; P<0.001), and chorioamnionitis nine (100%, P=0.002). Newborns delivered vaginally had a 4.11 times higher likelihood of poor outcomes compared to cesarean deliveries. Conclusion: Most NICU deaths resulted from prematurity and respiratory distress syndrome. Enhancing healthcare personnel skills, standardizing protocols, and evidence-based practices for preterm and respiratory 0distress syndrome management can help reduce neonatal mortality rates in Iraq.
背景:2021年,伊拉克的新生儿死亡率在中东地区排名第三,每1 000例活产死亡14人。& # x0D;目的:探讨新生儿重症监护病房不良预后的影响因素。 患者和方法:一项回顾性队列研究于2022年4月1日至9月31日进行,涉及632名新生儿。使用预先设计的表格收集所需的数据和结果。 结果:新生儿重症监护病房病死率为23.9%,其中64.9%发生在新生儿出生后6 d内。总死亡率为每1000例活产38.5例。死亡新生儿的胎龄和出生体重显著降低(P<0.001)。早产、呼吸窘迫综合征和先天性异常分别占死亡人数的94%、73.5%和20.5%。RDS 111患者的死亡率明显更高(56.3%;P<0.001),肺出血9例(100%;P<0.001),败血症26例(74.3%;(P= 0.001),绒毛膜羊膜炎9例(100%,P=0.002)。阴道分娩的新生儿预后不良的可能性是剖宫产的4.11倍。结论:新生儿重症监护病房死亡以早产和呼吸窘迫综合征为主。提高医护人员的技能、标准化规程以及早产儿和呼吸窘迫综合征管理方面的循证实践,有助于降低伊拉克的新生儿死亡率。
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引用次数: 0
Plasma level of ADAMTS-13 in maintenance hemodialysis patients and its relation to arteriovenous fistula thrombosis 维持性血液透析患者血浆ADAMTS-13水平及其与动静脉瘘血栓形成的关系
Pub Date : 2023-10-31 DOI: 10.26505/djm.v25i1.1020
Saja Hammadi Fahad ,, Najiha Ahmed Ameen
Background: End-stage renal disease is the final stage of chronic kidney disease in which irreversible deterioration in renal function occur and the body fails to maintain fluid and electrolyte balance, this need regular hemodialysis (HD) a process that removes accumulated solute from a patient with near-total renal function loss. Arteriovenous fistula (AVF) is the vascular access of choice for patients who require hemodialysis. AVF thrombosis is a major issue in hemodialysis patients, which increase their morbidity and lessen HD efficiency. Objective: To assess plasma level of ADAMTS-13 in HD patients and its association with AVF thrombosis, and to correlate the plasma level of ADAMTS-13 with age, duration of dialysis, certain hematological parameters and estimated GFR. Patients and Methods:This Cross_sectional study done on 60 patients with ESRD on regular HD sessions, 20 healthy persons were included as a control . The patients subdivided into two subgroups with and without AVF thrombosis. Plasma samples were freezed until the test for the level of ADAMTS-13 was done. Results: The plasma ADAMTS-13 level was significantly lower in HD patients compared to control group (P < 0.001), and was a significantly lower in patients with a history of AVF thrombosis than HD patients without a history of AVF thrombosis. HD patients with AVF thrombosis had significantly lower eGFR compared to patients without a history of AVF thrombosis. There was a positive correlation of plasma ADAMTS-13 level with the mean of eGFR , platelet count and negative correlation with MPV. Conclusion: Significant differences between HD patients and control regarding eGFR and hematological parameters . Plasma ADAMTS-13 level was significantly lower in patients compared to controls and significantly lower in patients group with AVF thrombosis than HD group without thrombosis.
背景:终末期肾病是慢性肾脏疾病的最后阶段,肾功能发生不可逆转的恶化,机体无法维持体液和电解质平衡,这需要定期的血液透析(HD),这一过程可以清除几乎完全肾功能丧失的患者体内积累的溶质。动静脉瘘(AVF)是需要血液透析的患者的首选血管通道。AVF血栓形成是血液透析患者的主要问题,它增加了血液透析患者的发病率,降低了血液透析的效率。 目的:探讨HD患者血浆ADAMTS-13水平及其与AVF血栓形成的关系,并探讨其与年龄、透析时间、某些血液学参数及GFR的相关性。患者和方法:本横断面研究对60例定期HD治疗的ESRD患者进行了研究,其中20名健康人作为对照。患者分为有和无AVF血栓形成两个亚组。血浆样品被冷冻,直到ADAMTS-13水平测试完成。 结果:HD患者血浆ADAMTS-13水平明显低于对照组(P <有AVF血栓形成史的HD患者比无AVF血栓形成史的HD患者明显降低。与没有AVF血栓病史的患者相比,伴有AVF血栓形成的HD患者eGFR明显降低。血浆ADAMTS-13水平与eGFR均值、血小板计数呈正相关,与MPV呈负相关。 结论:HD患者与对照组在eGFR和血液学指标方面存在显著差异。患者血浆ADAMTS-13水平明显低于对照组,AVF血栓形成组明显低于无血栓形成的HD组。
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Diyala Journal of Medicine
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