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Hyperbaric oxygen treatment in bilateral orchiopexy and post-circumcision haematoma in a thrombocytopenic patient with Noonan syndrome. 高压氧治疗一名患有努南综合征的血小板减少症患者的双侧睾丸切除术和包皮环切术后血肿。
IF 0.8 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-06-30 DOI: 10.28920/dhm54.2.133-136
Dilşad Dereli, Selahattin Çakiroğlu, Ayse Aydan Köse, Baran Tokar

Hyperbaric oxygen treatment (HBOT) can be utilised for necrotising soft tissue infections, clostridial myonecrosis (gas gangrene), crush injuries, acute traumatic ischaemia, delayed wound healing, and compromised skin grafts. Our case was a 17-month-old male patient with Noonan syndrome, idiopathic thrombocytopenic purpura, and bilateral undescended testicles. Haematoma and oedema developed in the scrotum and penis the day after bilateral orchiopexy and circumcision. Ischaemic appearances were observed on the penile and scrotal skin on the second postoperative day. Enoxaparin sodium and fresh frozen plasma were started on the recommendation of haematology. Hyperbaric oxygen treatment was initiated considering the possibility of tissue necrosis. We observed rapid healing within five days. We present this case to emphasise that HBOT may be considered as an additional treatment option in patients with similar conditions. To our knowledge, no similar cases have been reported in the literature.

高压氧治疗(HBOT)可用于软组织坏死性感染、梭菌性肌坏死(气性坏疽)、挤压伤、急性创伤性缺血、伤口延迟愈合和受损植皮。我们的病例是一名 17 个月大的男性患者,患有努南综合征、特发性血小板减少性紫癜和双侧睾丸下垂。双侧睾丸切除术和包皮环切术后第二天,阴囊和阴茎出现血肿和水肿。术后第二天,阴茎和阴囊皮肤出现缺血症状。根据血液科的建议,开始使用依诺肝素钠和新鲜冰冻血浆。考虑到组织坏死的可能性,我们启动了高压氧治疗。我们观察到伤口在五天内迅速愈合。我们介绍这一病例是为了强调,高压氧治疗可作为类似情况患者的额外治疗选择。据我们所知,文献中还没有类似病例的报道。
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引用次数: 0
Shunt-mediated decompression sickness in a compressed air worker with an atrial septal defect. 一名患有房间隔缺损的压缩空气工人的分流介导的减压病。
IF 0.8 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-06-30 DOI: 10.28920/dhm54.2.127-132
Andrew P Colvin, Ryan Hogg, Peter T Wilmshurst

We report a compressed air worker who had diffuse cutaneous decompression sickness with pain in his left shoulder and visual disturbance characteristic of migraine aura after only his third hyperbaric exposure. The maximum pressure was 253 kPa gauge with oxygen decompression using the Swanscombe Oxygen Decompression Table. He was found to have a very large right-to-left shunt across a 9 mm atrial septal defect. He had transcatheter closure of the defect but had some residual shunting with release of a Valsalva manoeuvre. Thirty-two other tunnel workers undertook the same pressure profile and activities in the same working conditions during the maintenance of a tunnel boring machine for a total of 233 similar exposures and were unaffected. As far as we are aware this is the first report of shunt-mediated decompression sickness in a hyperbaric tunnel worker in the United Kingdom and the second case reported worldwide. These cases suggest that shunt-mediated decompression sickness should be considered to be an occupational risk in modern compressed air working. A right-to-left shunt in a compressed air worker should be managed in accordance with established clinical guidance for divers.

我们报告了一名压缩空气工人仅在第三次高压氧暴露后就出现了弥漫性皮肤减压病,左肩疼痛,并伴有偏头痛先兆的视觉障碍。使用 Swanscombe 氧气减压表进行氧气减压时,最大压力为 253 kPa。他被发现在 9 毫米的房间隔缺损处有一个非常大的右向左分流。他接受了经导管的缺损闭合术,但在做瓦尔萨尔瓦动作时仍有一些残留的分流。另外 32 名隧道工人在维护一台隧道掘进机时,在相同的工作条件下进行了相同的压力曲线和活动,总共接触了 233 次类似的压力,但均未受到影响。据我们所知,这是英国第一例关于高压氧隧道工人分流介导的减压病的报告,也是全球第二例报告。这些病例表明,分流介导的减压病应被视为现代压缩空气工作中的一种职业风险。压缩空气工人的右至左分流应根据潜水员的既定临床指南进行处理。
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引用次数: 0
The use of hyperbaric oxygen for avascular necrosis of the femoral head and femoral condyle: a single centre's experience over 30 years. 使用高压氧治疗股骨头和股骨髁的血管性坏死:一个中心 30 年来的经验。
IF 0.8 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-06-30 DOI: 10.28920/dhm54.2.92-96
John Rb Currie, Ian C Gawthrope, Neil D Banham

Introduction: Avascular necrosis (AVN) is a rare progressive degenerative disease leading to bone and joint destruction. Patients often require surgical intervention. Femoral AVN is the most common anatomical location. Hyperbaric oxygen treatment (HBOT) has been shown to be effective in AVN. We present data collected from one centre over a 30-year period and compare the results with other published data.

Methods: A retrospective chart review of all patients receiving HBOT for AVN at Fremantle and Fiona Stanley Hospitals since 1989 was performed. The primary outcome was radiological appearance using the Steinberg score, with secondary outcomes being subjective improvement, the need for joint replacement surgery and rates of complications.

Results: Twenty-one joints in 14 patients (14 femoral heads and seven femoral condyles) were treated with HBOT since 1989. Two patients were excluded. Within the femoral head group, nine of the 14 joints (64%) had stable or improved magnetic resonance imaging (MRI) scans post treatment and at six months (minimum); 10 joints (71%) had good outcomes subjectively, three joints required surgical intervention, and three patients developed mild aural barotrauma. Within the femoral condyle group, all five joints had stable or improved post-treatment MRI scans (four had visible improvement in oedema and/or chondral stability), four joints reported good outcomes subjectively, none of the patients required surgical intervention (follow-up > six months).

Conclusions: This single centre retrospective study observed prevention of disease progression in femoral AVN with the use of HBOT, comparable to other published studies. This adds to the body of evidence that HBOT may have a significant role in the treatment of femoral AVN.

导言:血管性坏死(AVN)是一种罕见的渐进性退行性疾病,会导致骨和关节破坏。患者通常需要手术治疗。股骨头坏死是最常见的解剖位置。高压氧治疗(HBOT)已被证明对 AVN 有效。我们介绍了一个中心在 30 年间收集的数据,并将结果与其他已发表的数据进行了比较:方法:我们对弗里曼特尔医院和菲奥娜-斯坦利医院自 1989 年以来接受 HBOT 治疗的所有 AVN 患者进行了回顾性病历审查。主要结果是使用斯坦伯格评分的放射学外观,次要结果是主观改善、关节置换手术需求和并发症发生率:自 1989 年以来,共有 14 名患者的 21 个关节(14 个股骨头和 7 个股骨髁)接受了 HBOT 治疗。有两名患者被排除在外。在股骨头组中,14个关节中有9个(64%)在治疗后和6个月后(最短)的磁共振成像(MRI)扫描结果稳定或有所改善;10个关节(71%)主观疗效良好,3个关节需要手术治疗,3名患者出现轻度耳压创伤。在股骨髁组中,所有五个关节在治疗后的核磁共振扫描结果均稳定或有所改善(四个关节的水肿和/或软骨稳定性有明显改善),四个关节的主观疗效良好,没有一名患者需要手术治疗(随访时间超过六个月):这项单中心回顾性研究观察到,使用 HBOT 可预防股骨头坏死的疾病进展,这与其他已发表的研究结果不相上下。这为 HBOT 在股骨头坏死治疗中发挥重要作用提供了更多证据。
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引用次数: 0
Formulating policies and procedures for managing diving related deaths: a whole of state engagement from frontline and hospital services in Tasmania. 制定管理潜水相关死亡的政策和程序:塔斯马尼亚州前线和医院服务的全州参与。
IF 0.8 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-06-30 DOI: 10.28920/dhm54.2.86-91
Elizabeth J Elliott, Karl Price, Bernard Peters

Introduction: Tasmania is a small island state off the southern edge of Australia where a comparatively high proportion of the 558,000 population partake in recreational or occupational diving. While diving is a relatively safe sport and occupation, Tasmania has a significantly higher diving death rate per head of population than other States in Australia (four times the national diving mortality rate).

Methods: Three compressed gas diving deaths occurred in seven months between 2021-2022 prompting a review of the statewide approach for the immediate response of personnel to diving-related deaths. The review engaged first responders including the Police Marine and Rescue Service, hospital-based departments including the Department of Hyperbaric and Diving Medicine, and the mortuary and coroner's office.

Results: An aide-mémoire for all craft groups, digitalised checklists for first responders (irrespective of diving knowledge), and a single-paged algorithm to highlight inter-agency communication pathways in the event of a diving death were designed to enhance current practices and collaboration.

Conclusions: If used, these aids for managing diving related deaths should ensure that time-critical information is appropriately captured and stored to optimise information provided for the coronial investigation.

导言:塔斯马尼亚州是澳大利亚南部边缘的一个小岛州,55.8 万人口中有相当高比例的人从事休闲或职业潜水活动。虽然潜水是一项相对安全的运动和职业,但塔斯马尼亚州的人均潜水死亡率却明显高于澳大利亚其他州(是全国潜水死亡率的四倍):方法:2021-2022 年间的七个月内发生了三起压缩气体潜水死亡事件,促使对全州范围内人员对潜水相关死亡事件的即时响应方法进行审查。审查涉及包括警察海洋和救援服务局在内的第一响应者、包括高压氧和潜水医学部在内的医院部门以及停尸房和验尸官办公室:结果:为所有船队设计的备忘录、为急救人员(无论是否具备潜水知识)设计的数字化核对表,以及在发生潜水死亡事件时强调机构间沟通途径的单页算法,都旨在加强当前的实践与合作:如果使用这些辅助工具来管理与潜水相关的死亡事件,就能确保适当捕获和存储时间关键信息,从而优化为死因调查提供的信息。
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引用次数: 0
Hyperbaric oxygen treatment for infants: retrospective analysis of 54 patients treated in two tertiary care centres. 婴儿高压氧治疗:对两个三级医疗中心治疗的 54 名患者的回顾性分析。
IF 0.8 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-31 DOI: 10.28920/dhm54.1.9-15
Kubra Ozgok Kangal, Bengusu Mirasoglu

Introduction: We aimed to analyse the outcomes of hyperbaric oxygen treatment (HBOT) and describe difficulties encountered in infants, a rare patient population in this therapeutic intervention, with limited scientific reports.

Methods: This was a retrospective analysis of patients 12 months old or younger who underwent HBOT in two different institutions. Demographic data, clinical presentation, HBOT indication, chamber type, oxygen delivery method, total number of treatments, outcome and complications were extracted from clinical records.

Results: There were 54 infants in our study. The patients' median age was 3.5 (range 0-12) months. The major HBOT indication was acute carbon monoxide intoxication (n = 32). A total of 275 HBOT treatments were administered, mostly performed in multiplace chambers (n = 196, 71%). Only one patient (2%) required mechanical ventilation. Acute signs were fully resolved in the most patients (n = 40, 74%). No complications related to HBOT were reported.

Conclusions: This study suggests that HBOT may be a safe and effective treatment for infants. Paediatricians should consider HBOT when indicated in infants even for the preterm age group.

简介:我们的目的是分析高压氧治疗(HBOT)的结果,并描述婴儿在这种治疗干预中遇到的困难:我们的目的是分析高压氧治疗(HBOT)的结果,并描述婴儿在这种治疗干预中遇到的困难:这是一项回顾性分析,对象是在两家不同机构接受高压氧治疗的 12 个月或 12 个月以下的患者。从临床记录中提取人口统计学数据、临床表现、HBOT 适应症、舱型、供氧方式、治疗总次数、治疗结果和并发症:我们的研究共涉及 54 名婴儿。结果:共有 54 名婴儿接受了 HBOT 治疗,中位年龄为 3.5 个月(0-12 个月)。HBOT 的主要适应症是急性一氧化碳中毒(32 例)。共进行了 275 次 HBOT 治疗,大部分是在多腔室中进行的(n = 196,71%)。只有一名患者(2%)需要机械通气。大多数患者的急性体征完全消失(40 人,占 74%)。没有与 HBOT 相关的并发症报告:这项研究表明,HBOT 是一种安全有效的婴儿治疗方法。儿科医生应考虑对婴儿进行 HBOT 治疗,即使是早产儿也不例外。
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引用次数: 0
Efficacy of searching in biomedical databases beyond MEDLINE in identifying randomised controlled trials on hyperbaric oxygen treatment. 在 MEDLINE 之外的生物医学数据库中搜索高压氧治疗随机对照试验的效果。
IF 0.8 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-31 DOI: 10.28920/dhm54.1.2-8
Hira Khan, Mohammad Sindeed Islam, Manvinder Kaur, Joseph K Burns, Cole Etherington, Pierre-Marc Dion, Sarah Alsayadi, Sylvain Boet

Introduction: Literature searches are routinely used by researchers for conducting systematic reviews as well as by healthcare providers, and sometimes patients, to quickly guide their clinical decisions. Using more than one database is generally recommended but may not always be necessary for some fields. This study aimed to determine the added value of searching additional databases beyond MEDLINE when conducting a literature search of hyperbaric oxygen treatment (HBOT) randomised controlled trials (RCTs).

Methods: This study consisted of two phases: a scoping review of all RCTs in the field of HBOT, followed by a a statistical analysis of sensitivity, precision, 'number needed to read' (NNR) and 'number unique' included by individual biomedical databases. MEDLINE, Embase, Cochrane Central Register of Control Trials (CENTRAL), and Cumulated Index to Nursing and Allied Health Literature (CINAHL) were searched without date or language restrictions up to December 31, 2022. Screening and data extraction were conducted in duplicate by pairs of independent reviewers. RCTs were included if they involved human subjects and HBOT was offered either on its own or in combination with other treatments.

Results: Out of 5,840 different citations identified, 367 were included for analysis. CENTRAL was the most sensitive (87.2%) and had the most unique references (7.1%). MEDLINE had the highest precision (23.8%) and optimal NNR (four). Among included references, 14.2% were unique to a single database.

Conclusions: Systematic reviews of RCTs in HBOT should always utilise multiple databases, which at minimum include MEDLINE, Embase, CENTRAL and CINAHL.

导言:文献检索是研究人员进行系统综述的常规手段,也是医疗服务提供者(有时是患者)快速指导临床决策的手段。一般建议使用一个以上的数据库,但在某些领域可能并非总是必要的。本研究旨在确定在对高压氧治疗(HBOT)随机对照试验(RCT)进行文献检索时,检索MEDLINE之外的其他数据库的附加价值:这项研究包括两个阶段:对高压氧治疗领域的所有 RCT 进行范围界定,然后对各个生物医学数据库收录的敏感性、精确性、"需要阅读的数量"(NNR)和 "唯一数量 "进行统计分析。对截至 2022 年 12 月 31 日的 MEDLINE、Embase、Cochrane Central Register of Control Trials (CENTRAL) 和 Cumulated Index to Nursing and Allied Health Literature (CINAHL) 进行了检索,没有日期或语言限制。筛选和数据提取由一对独立审稿人重复进行。如果RCT涉及人类受试者,且HBOT可单独使用或与其他疗法联合使用,则将其纳入检索范围:结果:在已确定的 5,840 篇不同引文中,有 367 篇被纳入分析。CENTRAL 的灵敏度最高(87.2%),唯一参考文献最多(7.1%)。MEDLINE 的精确度最高(23.8%),NNR 最佳(4)。在纳入的参考文献中,14.2%为单一数据库的唯一参考文献:结论:HBOT RCT 的系统综述应始终使用多个数据库,其中至少包括 MEDLINE、Embase、CENTRAL 和 CINAHL。
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引用次数: 0
Time to shock people. 是时候震撼人心了
IF 0.8 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-31 DOI: 10.28920/dhm54.1.73-74
Gerard Laden, Bruce Mathew, Ananthakrishnan Ananthasayanam
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引用次数: 0
Decompression illness: a comprehensive overview. 减压病:全面概述。
IF 0.8 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-31 DOI: 10.28920/dhm54.1.suppl.1-53
Simon J Mitchell

Decompression illness is a collective term for two maladies (decompression sickness [DCS] and arterial gas embolism [AGE]) that may arise during or after surfacing from compressed gas diving. Bubbles are the presumed primary vector of injury in both disorders, but the respective sources of bubbles are distinct. In DCS bubbles form primarily from inert gas that becomes dissolved in tissues over the course of a compressed gas dive. During and after ascent ('decompression'), if the pressure of this dissolved gas exceeds ambient pressure small bubbles may form in the extravascular space or in tissue blood vessels, thereafter passing into the venous circulation. In AGE, if compressed gas is trapped in the lungs during ascent, pulmonary barotrauma may introduce bubbles directly into the pulmonary veins and thence to the systemic arterial circulation. In both settings, bubbles may provoke ischaemic, inflammatory, and mechanical injury to tissues and their associated microcirculation. While AGE typically presents with stroke-like manifestations referrable to cerebral involvement, DCS can affect many organs including the brain, spinal cord, inner ear, musculoskeletal tissue, cardiopulmonary system and skin, and potential symptoms are protean in both nature and severity. This comprehensive overview addresses the pathophysiology, manifestations, prevention and treatment of both disorders.

减压病是两种疾病(减压病(DCS)和动脉气体栓塞(AGE))的统称,这两种疾病可能在压缩气体潜水期间或浮出水面后出现。气泡被认为是这两种疾病的主要伤害媒介,但气泡的来源各不相同。在 DCS 中,气泡主要由在压缩气体潜水过程中溶解在组织中的惰性气体形成。在上升过程中和上升后("减压"),如果溶解气体的压力超过环境压力,就会在血管外空间或组织血管中形成小气泡,随后进入静脉循环。在 AGE 中,如果压缩气体在上升过程中滞留在肺部,肺气压创伤可能会将气泡直接引入肺静脉,然后进入全身动脉循环。在这两种情况下,气泡都可能对组织及其相关微循环造成缺血性、炎症性和机械性损伤。AGE 通常表现为类似中风的症状,可累及大脑,而 DCS 则可影响多个器官,包括大脑、脊髓、内耳、肌肉骨骼组织、心肺系统和皮肤,而且潜在症状的性质和严重程度都很复杂。本综述全面介绍了这两种疾病的病理生理学、表现、预防和治疗。
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引用次数: 0
Review of saturation decompression procedures used in commercial diving. 回顾商业潜水中使用的饱和减压程序。
IF 0.9 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-31 DOI: 10.28920/dhm54.1.23-38
Jean-Pierre Imbert, Lyubisa Matity, Jean-Yves Massimelli, Philip Bryson

Introduction: This is a review of commercial heliox saturation decompression procedures. The scope does not include compression, storage depth or bell excursion dive procedures. The objectives are to: identify the sources of the procedures; trace their evolution; describe the current practice; and detect relevant trends.

Methods: Eleven international commercial diving companies provided their diving manuals for review under a confidentiality agreement.

Results: Modern commercial diving saturation procedures are derived from a small number of original procedures (United States Navy, Comex, and NORSOK). In the absence of relevant scientific studies since the late 80's, the companies have empirically adapted these procedures according to their needs and experience. Such adaptation has caused differences in decompression rates shallower than 60 msw, decompression rest stops and the decision to decompress linearly or stepwise. Nevertheless, the decompression procedures present a remarkable homogeneity in chamber PO2 and daily decompression rates when deeper than 60 msw. The companies have also developed common rules of good practice; no final decompression should start with an initial ascending excursion; a minimum hold is required before starting a final decompression after an excursion dive. Recommendation is made for the divers to exercise during decompression.

Conclusions: We observed a trend towards harmonisation within the companies that enforce international procedures, and, between companies through cooperation inside the committees of the industry associations.

导言:这是对商用氦氧饱和减压程序的回顾。范围不包括压缩、储存深度或钟罩偏移潜水程序。目的是:确定程序的来源;追踪其演变过程;描述当前的做法;以及发现相关趋势:方法:11 家国际商业潜水公司根据保密协议提供了他们的潜水手册供审查:结果:现代商业潜水饱和程序源自少数原始程序(美国海军、Comex 和 NORSOK)。自 80 年代末以来,由于缺乏相关的科学研究,各公司根据自己的需要和经验对这些程序进行了经验性调整。这种调整造成了减压率(水深低于 60 米)、减压休息站以及线性减压或阶梯式减压决定等方面的差异。尽管如此,当水深超过 60 米时,减压程序在舱内 PO2 和每日减压率方面呈现出显著的一致性。各公司还制定了良好做法的共同规则;在最初上升的短途潜水中不得开始最后减压;在短途潜水后开始最后减压前,必须保持最短的时间。建议潜水员在减压期间进行锻炼:我们注意到,在执行国际程序的公司内部,以及通过行业协会委员会内部的合作在公司之间出现了统一的趋势。
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引用次数: 0
Secondary deterioration in a patient with cerebral and coronary arterial gas embolism after brief symptom resolution: a case report. 一名脑部和冠状动脉气体栓塞患者在症状短暂缓解后病情继发恶化:病例报告。
IF 0.8 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH Pub Date : 2024-03-31 DOI: 10.28920/dhm54.1.61-64
Ryota Tsushima, Kosuke Mori, Shohei Imaki

Introduction: Hyperbaric oxygen treatment (HBOT) is recommended for arterial gas embolism (AGE) with severe symptoms. However, once symptoms subside, there may be a dilemma to treat or not.

Case presentation: A 71-year-old man was noted to have a mass shadow in his left lung, and a transbronchial biopsy was performed with sedation. Flumazenil was intravenously administered at the end of the procedure. However, the patient remained comatose and developed bradycardia, hypotension, and ST-segment elevation in lead II. Although the ST changes spontaneously resolved, the patient had prolonged disorientation. Whole- body computed tomography revealed several black rounded lucencies in the left ventricle and brain, confirming AGE. The patient received oxygen and remained supine. His neurological symptoms gradually improved but worsened again, necessitating HBOT. HBOT was performed seven times, after which neurological symptoms resolved almost completely.

Conclusions: AGE can secondarily deteriorate after symptoms have subsided. We recommend that HBOT be performed promptly once severe symptoms appear, even if they resolve spontaneously.

简介建议对症状严重的动脉气体栓塞(AGE)患者进行高压氧治疗(HBOT)。然而,一旦症状消退,治疗与否可能会陷入两难境地:一名 71 岁的男性被发现左肺有肿块阴影,在镇静状态下进行了经支气管活检。手术结束后静脉注射了氟马西尼。然而,患者仍处于昏迷状态,并出现心动过缓、低血压和 II 导联 ST 段抬高。虽然ST段变化自发消失了,但患者出现了长时间的意识障碍。全身计算机断层扫描显示,左心室和脑部出现多个黑色圆形通透点,证实了AGE。患者接受了吸氧并保持仰卧。他的神经症状逐渐好转,但又再次恶化,因此必须进行 HBOT。共进行了七次 HBOT,之后神经症状几乎完全缓解:结论:AGE 可在症状缓解后二次恶化。我们建议,一旦出现严重症状,即使症状自行缓解,也应立即进行 HBOT 治疗。
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引用次数: 0
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Diving and hyperbaric medicine
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