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Police-issued barring notices in Western Australia: An analysis of the type, seriousness and trajectory of associated offences 西澳大利亚州警方签发的禁止令:对相关罪行的类型、严重程度和发展轨迹的分析。
IF 3 3区 医学 Q2 SUBSTANCE ABUSE Pub Date : 2024-07-30 DOI: 10.1111/dar.13916
Clare Farmer, Nicholas Taylor, Ryan Baldwin, Peter G. Miller

Introduction

Police-issued barring notices are currently used in Western Australia in response to alcohol-related disorderly and anti-social behaviour. This paper examines the type, severity and trajectory of the offending behaviours associated with served barring notices.

Method

WA Police Force de-identified the data for 3815 individuals who had received one or more police-imposed barring notice/s between 2011 and 2020. The offence category associated with each barring notice was examined to explore the overall breakdown and whether/how offending categories change for recipients of subsequent barring notices.

Results

For single and multiple barring notice recipients, the most common offence categories were fighting/physical violence and public order offences. Within a subset of the data, non-anti-social offences also spiked. Aggressive behaviours predominate for recipients in metropolitan areas, compared with public order offences in regional locations.

Discussion and Conclusions

For recipients of multiple barring notices, behaviours do not become more serious but neither do they moderate to any notable extent. The low number of repeat barring notices (5%) may suggest an overall beneficial effect on recipient behaviours but more analysis is needed to examine the potential confounding effects of factors, such as fly-in/fly-out workers, policing and locational differences.

导言:西澳大利亚州目前使用警方签发的禁止令来应对与酒精有关的扰乱治安和反社会行为。本文研究了与禁止令相关的犯罪行为的类型、严重程度和轨迹:西澳大利亚州警察局对 2011 年至 2020 年间收到过一份或多份警方禁止令的 3815 人的数据进行了去标识化处理。研究了与每份禁止令相关的犯罪类别,以探讨总体细分情况,以及随后收到禁止令的人的犯罪类别是否/如何发生变化:对于单个和多个禁止令通知接收者而言,最常见的犯罪类别是打架斗殴/人身暴力和公共秩序犯罪。在部分数据中,非反社会犯罪也有所增加。与地区性的公共秩序犯罪相比,大都市地区的禁止令接收者主要以攻击行为为主:对于多次收到禁止令的人来说,其行为并没有变得更加严重,但也没有明显缓和。重复禁止令的数量较少(5%),这可能表明对接收者行为的总体影响是有益的,但还需要进行更多的分析,以研究飞入/飞出工作者、治安和地区差异等因素的潜在混杂效应。
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引用次数: 0
No- and low-alcohol beer and the sponsorship of sport in Australia: An audit of sponsorship partnerships and analysis of marketing tactics 澳大利亚的无酒精和低酒精啤酒与体育赞助:赞助伙伴关系审计和营销策略分析。
IF 3 3区 医学 Q2 SUBSTANCE ABUSE Pub Date : 2024-07-29 DOI: 10.1111/dar.13912
Mia Miller, Cassandra C. J. Wright

Introduction

Alcohol sponsorship of sport is associated with increased alcohol consumption. Little research to date has examined the sponsorship of sport by no- and low-alcohol (NoLo) beverage brands, despite concern that the marketing of these products might be harmful to young people. This study had dual aims: to identify sporting partnerships between NoLo beers and Australian sport, and examine marketing tactics used in social media advertising to promote these partnerships.

Methods

Our sample included NoLo beers sold online from three large Australian alcohol retailers. First, we performed a qualitative content analysis of partnerships between NoLo beers and sport using publicly available online information. We then analysed the 118 social media posts of NoLo brands linked to these partnerships using a coding framework adapted from the alcohol literature.

Results

Of 34 brands, 13 had sporting sponsorship partnerships across a range of spectator and participatory sports. Key marketing tactics identified on social media were activations, time-and event-specific drinking, influencer marketing, competitions, and corporate social responsibility. In particular, NoLo brands aim to disrupt the sports drink market by advertising their products as healthy recovery drinks, or ‘sports beers’, through activation events. Brands are also using influencer marketing and competitions, two tactics shown to be particularly persuasive for young people.

Discussion and Conclusions

NoLo beer brands strategically align with Australian sports to promote NoLo consumption. As they are classified as soft drinks in Australia, NoLo beverages are not regulated like alcohol. Future discussions around sports sponsorship and advertising regulation must consider NoLo products.

导言体育运动中的酒精赞助与酒精消费的增加有关。尽管人们担心无酒精和低酒精(NoLo)饮料品牌的营销可能会对年轻人造成伤害,但迄今为止几乎没有研究对这些品牌赞助体育运动的情况进行过调查。本研究具有双重目的:确定 NoLo 啤酒与澳大利亚体育之间的体育合作关系,并研究社交媒体广告中为促进这些合作关系而使用的营销策略:我们的样本包括澳大利亚三家大型酒类零售商在线销售的 NoLo 啤酒。首先,我们利用公开的在线信息对 NoLo 啤酒与体育运动之间的合作关系进行了定性内容分析。然后,我们使用从酒类文献中改编的编码框架,分析了118条与这些合作关系相关的NoLo品牌社交媒体帖子:结果:在 34 个品牌中,有 13 个品牌与一系列观赏性和参与性体育运动建立了体育赞助合作关系。在社交媒体上发现的主要营销策略有:活动、特定时间和事件的饮酒、影响者营销、竞赛和企业社会责任。特别是,NoLo 品牌旨在通过激活活动将其产品宣传为健康恢复饮料或 "运动啤酒",从而颠覆运动饮料市场。品牌还利用影响者营销和竞赛,这两种策略对年轻人特别有说服力:NoLo啤酒品牌战略性地与澳大利亚体育运动相结合,以促进NoLo啤酒的消费。由于 NoLo 饮料在澳大利亚被归类为软饮料,因此不像酒精饮料那样受到监管。未来有关体育赞助和广告监管的讨论必须考虑 NoLo 产品。
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引用次数: 0
A 3-year retrospective review of hospital admissions involving opioid toxicity in South Australia 对南澳大利亚州阿片类药物中毒住院病例的三年回顾。
IF 3 3区 医学 Q2 SUBSTANCE ABUSE Pub Date : 2024-07-29 DOI: 10.1111/dar.13913
Maria Sarantou, Anne L. J. Burke, Tim Semple, Jacinta L. Johnson

Introduction

This article aims to characterise hospital admissions involving opioid toxicity across South Australia to guide future implementation and evaluation of risk mitigation strategies.

Methods

International Classification of Diseases, 10th Edition codes (T40.0–T40.4) were used to identify admissions involving pre-hospital opioid toxicity in public hospitals across South Australia from 1 June 2017 to 30 August 2020. Demographic and episode of care data were extracted and summarised using descriptive statistics. Admission cost estimates were calculated using Independent Hospital Pricing Authority data.

Results

A total of 2046 cases met the criteria for inclusion; over half (56%) were female and median age on admission was 44 years (interquartile range 27 years). Where opioid toxicity was the primary diagnosis, 70% of admissions did not specify the responsible opioid and 23% were related to heroin use. One-fifth of admissions occurred outside of metropolitan Adelaide. Individuals living in an area of relative socio-economic disadvantage were over-represented. Over half of admissions required a stay >24 h; 19% were admitted for ≥5 days, 22% required intensive care and ~10% required mechanical ventilation. The total estimated cost of admissions involving opioid toxicity in South Australia over the 3-year period was $18,230,546.50, equating to $5.6 million per annum.

Discussions and Conclusions

These findings highlight the significant personal, fiscal, and systemic impacts of opioid toxicity-related hospital admissions in South Australia and provide a baseline to evaluate the effectiveness of initiatives to reduce opioid-related harm, including real-time prescription monitoring and take-home naloxone supply.

导言:本文旨在描述南澳大利亚州涉及阿片类药物中毒的入院情况,以指导未来风险缓解策略的实施和评估:方法:采用《国际疾病分类》第10版代码(T40.0-T40.4)识别2017年6月1日至2020年8月30日期间南澳大利亚州公立医院中涉及院前阿片类药物中毒的入院病例。采用描述性统计方法提取并汇总了人口统计学数据和医疗事件数据。入院成本估算采用独立医院定价局的数据进行计算:共有 2046 个病例符合纳入标准;一半以上(56%)为女性,入院年龄中位数为 44 岁(四分位数间距为 27 岁)。在以阿片类药物中毒为主要诊断的病例中,70%的入院病例没有说明是哪种阿片类药物引起的,23%的病例与海洛因的使用有关。五分之一的入院患者居住在阿德莱德市区以外。生活在社会经济相对落后地区的患者比例较高。超过一半的入院患者需要住院超过24小时;19%的患者住院时间超过5天,22%的患者需要重症监护,约10%的患者需要机械通气。在这3年期间,南澳大利亚州涉及阿片类药物中毒的住院总费用估计为18,230,546.50澳元,相当于每年560万澳元:这些研究结果突显了南澳大利亚州与阿片类药物中毒相关的入院治疗对个人、财政和系统造成的重大影响,并为评估减少阿片类药物相关伤害的措施(包括实时处方监控和带回家的纳洛酮供应)的有效性提供了基准。
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引用次数: 0
Consumption of alcohol-free and alcoholic beverages among Dutch university students: Substitution or addition? 荷兰大学生饮用无酒精饮料和含酒精饮料的情况:替代还是补充?
IF 3 3区 医学 Q2 SUBSTANCE ABUSE Pub Date : 2024-07-26 DOI: 10.1111/dar.13905
Martine M. Groefsema, Kirsten J. M. van Hooijdonk, Carmen V. Voogt, Hanneke Hendriks, Jacqueline M. Vink

Introduction

Alcohol-free drinks are suggested as healthy alternatives for alcohol consumption. To achieve benefits, alcohol-free beverages must be consumed as a substitute for alcoholic beverages, not in addition. This study examined in a student sample (i) the frequency/quantity of alcohol(-free) consumption; (ii) the relationship between alcohol-free and alcohol consumption; (iii) alcohol-free drinks as substitution or in addition to alcoholic drinks; and (iv) possible gender differences.

Methods

Survey data regarding alcohol(-free) consumption (May–June 2022) of Dutch university students (N = 4.318, females 70.2%; males 28.5%, average age 22.6 years [SD = 2.4]).

Results

(i) A total of 42.8% of the students indicated they had never consumed alcohol-free versus 10.1% who never consumed alcoholic beverages; (ii) the group who recently consumed alcohol-free also most often recently consumed alcoholic beverages (42.7%). The group that had never consumed alcohol-free drank on average more alcoholic beverages (M = 3.98 on a drinking day) compared to past and recent alcohol-free drinkers (respectively, M = 3.44 and M = 3.59). (iii) Most students (54.9%) reported drinking alcohol-free beverages in addition to alcohol, 17.4% indicated using it as a substitution. Students who consumed alcohol-free as ‘substitution’ were older, more often living alone or with a partner, less often living with parents and more often involved in a steady relationship compared to students who consumed in ‘addition’. (iv) No prominent gender differences were found.

Discussion and Conclusions

The majority of students remained consuming the same number of alcoholic beverages since they started consuming alcohol-free beverages, pointing to an addition effect. A small group did use alcohol-free beverages as a substitute for their alcohol consumption.

导言:无酒精饮料被建议作为酒精消费的健康替代品。无酒精饮料必须作为含酒精饮料的替代品饮用,而不是额外饮用,才能获得益处。本研究对学生样本进行了调查:(i) 无酒精饮料的消费频率/数量;(ii) 无酒精饮料与酒精消费之间的关系;(iii) 无酒精饮料是酒精饮料的替代品还是补充品;(iv) 可能存在的性别差异:结果:(i) 共有 42.8%的学生表示从未饮用过无酒精饮料,而 10.1%的学生从未饮用过含酒精饮料;(ii) 最近饮用无酒精饮料的群体最近也最常饮用含酒精饮料(42.7%)。与过去和最近不饮酒者(分别为 M = 3.44 和 M = 3.59)相比,从未饮酒者平均饮酒量更高(饮酒日 M = 3.98)。(iii) 大部分學生(54.9%)表示除飲用酒精飲品外,還會飲用不含酒精飲品, 17.4%表示會以不含酒精飲品代替酒精飲品。与 "补充 "饮用的学生相比,"替代 "饮用不含酒精饮料的学生年龄更大,更经常独居或与伴侣同住,较少与父母同住,更经常有稳定的恋爱关系。(iv) 没有发现明显的性别差异:大多数学生自开始饮用无酒精饮料以来,饮用酒精饮料的数量保持不变,这表明存在 "加量 "效应。一小部分学生确实使用无酒精饮料作为酒精消费的替代品。
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引用次数: 0
Countering stereotypes: Exploring the characteristics of Aboriginal Australians who do not drink alcohol in a community representative sample 消除陈规定型观念:在社区代表性样本中探索不饮酒的澳大利亚原住民的特征。
IF 3 3区 医学 Q2 SUBSTANCE ABUSE Pub Date : 2024-07-23 DOI: 10.1111/dar.13907
James H. Conigrave, Scott Wilson, Katherine M. Conigrave, Jimmy Perry, Noel Hayman, Tanya N. Chikritzhs, Dan Wilson, Catherine Zheng, Teagan J. Weatherall, K. S. Kylie Lee

Introduction

Contrary to stereotypes, Aboriginal and Torres Strait Islander Australians are more likely to abstain from drinking than other Australians. We explored characteristics and experiences of Aboriginal and Torres Strait Islander Australians who do not drink alcohol.

Method

We conducted a cross-sectional, representative survey of 775 Aboriginal and Torres Strait Islander Australians (16+ years) in remote and urban South Australia. We explore correlates of not drinking alcohol using multi-level logistic regression. We describe reasons for non-drinking and harms participants experienced in past 12 months from others' drinking.

Results

Non-drinking participants were more likely to be older (OR 1.35 [95% CI 1.21, 1.50] per decade) and unemployed (OR 2.72 [95% CI 1.77, 4.20]). Participants who spoke Aboriginal Australian languages at home were three times more likely to be lifetime abstainers from drinking (OR 3.07 [95% CI 1.52, 6.21]). Common reasons for not drinking alcohol were health and family. Most did not report harms from others' alcohol consumption (79.6%, 76.9%, urban and remote respectively). Stress from others' alcohol consumption was the most reported harm by non-drinkers (14.5% and 23.1%, urban and remote, respectively).

Discussion and Conclusions

Culture such as speaking Aboriginal Australian languages might have protective effects that promote abstaining but was rarely explicitly cited as a reason for not drinking. A greater understanding of local values held by people who do not drink alcohol could help inform health messaging and other interventions to reduce alcohol-related harms. Understanding local reasons for abstaining can help tailor health messaging to suit local contexts.

导言:与刻板印象相反,澳大利亚土著居民和托雷斯海峡岛民比其他澳大利亚人更有可能戒酒。我们探讨了不饮酒的澳大利亚原住民和托雷斯海峡岛民的特点和经历:我们对南澳大利亚偏远地区和城市的 775 名澳大利亚原住民和托雷斯海峡岛民(16 岁以上)进行了横断面代表性调查。我们采用多级逻辑回归法探讨了不饮酒的相关因素。我们描述了不饮酒的原因以及参与者在过去 12 个月中因他人饮酒而受到的伤害:不饮酒的参与者更有可能年龄较大(OR 1.35 [95% CI 1.21, 1.50]/10)和失业(OR 2.72 [95% CI 1.77, 4.20])。在家讲澳大利亚土著语言的参与者终生不饮酒的可能性是其他参与者的三倍(OR 3.07 [95% CI 1.52, 6.21])。不饮酒的常见原因是健康和家庭。大多数人没有报告过他人饮酒造成的伤害(城市和偏远地区分别为 79.6%、76.9%)。不饮酒者报告最多的伤害是他人饮酒带来的压力(城市和偏远地区分别为 14.5%和 23.1%):澳大利亚土著语言等文化可能具有促进戒酒的保护作用,但很少被明确作为不饮酒的原因。更深入地了解当地不饮酒者的价值观,有助于为健康信息和其他干预措施提供依据,减少酒精相关危害。了解当地人不饮酒的原因有助于因地制宜地制定健康信息。
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引用次数: 0
Patterns of substance use recovery following residential treatment: A repeated measures latent profile analysis 住院治疗后的药物使用康复模式:重复测量潜在特征分析。
IF 3 3区 医学 Q2 SUBSTANCE ABUSE Pub Date : 2024-07-23 DOI: 10.1111/dar.13904
Laura D. Robinson, Tayla J. Degan, Frank P. Deane, Peter J. Kelly

Introduction

Ongoing improvement to residential treatment for substance use disorders is critical as it typically targets people with the highest need. Assessing multiple recovery indicators, such as cravings and mental health, at intake and following discharge is important in evaluating treatment effectiveness. To refine services, research should explore whether there are subgroups of individuals with different patterns of recovery following treatment.

Methods

Participants (n = 554) were attending Australian Salvation Army residential treatment services for substance use issues. Data were collected by surveys at intake and 3-month post-discharge (‘early recovery’). Recovery indicators were cravings, confidence to resist substance use and the Depression, Anxiety and Stress Scale. Subgroups of individuals based on these recovery indicators (‘profiles’) were identified using repeated measures latent profile analysis.

Results

Five profiles were identified, three profiles improved over time (81.4%) and two (18.6%) deteriorated across all indicators. These two profiles had the poorest mental health and addiction scores at intake and reported shorter time in treatment compared to the three profiles showing improvement. There were no demographic or substance type differences between profiles.

Discussion and Conclusions

By considering initial severity and multiple recovery indicators at early recovery, this study suggests that individuals at-risk of poor early recovery can be identified at intake. This opens opportunities for tailored treatment approaches to address both mental health and substance use, thereby potentially improving treatment outcomes and reducing the risk of relapse.

导言:持续改善药物使用障碍的住院治疗至关重要,因为它通常针对的是需求最大的人群。在入院时和出院后评估多种康复指标(如渴望和心理健康)对于评估治疗效果非常重要。为了完善服务,研究应探讨是否存在治疗后康复模式不同的亚群体:参与者(n = 554)因药物使用问题接受了澳大利亚救世军的住院治疗服务。数据通过入院时和出院后 3 个月("早期康复")的调查收集。康复指标包括渴望程度、抵制药物使用的信心以及抑郁、焦虑和压力量表。根据这些康复指标("特征"),采用重复测量潜特征分析法确定了个人的分组:结果:共确定了五个特征,其中三个特征随着时间的推移有所改善(81.4%),两个特征(18.6%)在所有指标上都有所恶化。这两例患者在入院时的心理健康和成瘾评分最差,与三例病情好转的患者相比,他们接受治疗的时间更短。不同情况之间没有人口统计或药物类型上的差异:通过考虑早期康复的初始严重程度和多种康复指标,本研究表明,可以在入院时识别出早期康复不佳的高危人群。这就为同时解决心理健康和药物使用问题的针对性治疗方法提供了机会,从而有可能改善治疗效果并降低复发风险。
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引用次数: 0
Estimating the alcohol-related burden of child maltreatment among Māori in Aotearoa, New Zealand 估算新西兰奥特亚罗瓦毛利人中与酒精有关的虐待儿童负担。
IF 3 3区 医学 Q2 SUBSTANCE ABUSE Pub Date : 2024-07-21 DOI: 10.1111/dar.13906
Taisia Huckle, Helen Moewaka Barnes, Jose S. Romeo

Introduction

To assesses the alcohol-related burden of child maltreatment among Māori in Aotearoa New Zealand. We compared the risk of child maltreatment among Māori (0–17 years) exposed to parents with alcohol-related hospitalisation or mental health/addiction service use. We also conducted a sensitivity analysis to estimate the number of cases of maltreatment that could be attributed to alcohol among Māori.

Methods

A cohort study of 16,617 Māori aged 0–17 and their parents from 2000 to 2017 was conducted using the Statistics New Zealand Integrated Data Infrastructure. A Bayesian piecewise exponential model estimated the risk of time to first child maltreatment event. This analysis used data from child protection, hospital, mortality and police records, and specifically focused on the risk associated with exposure to parents with an alcohol-attributable hospitalisation or mental health/addiction service use event. Potential confounders for both parents and Māori (0–17 years) were included. We calculated a population-attributable fraction to estimate the proportion of maltreatment cases that could be attributed to alcohol in 2017.

Results

Results showed a 65% increased risk for young Māori exposed to parents with heavy alcohol use. We estimated 17% of substantiated child maltreatment among Māori could be attributed to parental hazardous alcohol consumption.

Discussion and Conclusions

Severe or hazardous alcohol consumption among parents is a risk factor for child maltreatment among Māori. Māori alcohol consumption and harm are symptomatic of wider inequities related, among other things, to the ongoing effects of colonisation, as well as gaps in the regulation of alcohol sales.

导言:目的:评估新西兰奥特亚罗瓦毛利人中与酒精有关的儿童虐待负担。我们比较了毛利人(0-17岁)因父母酗酒住院或使用精神健康/成瘾服务而遭受虐待的风险。我们还进行了一项敏感性分析,以估计毛利人中可归因于酒精的虐待案例数量:我们利用新西兰统计局综合数据基础设施(Statistics New Zealand Integrated Data Infrastructure)对2000年至2017年期间的16617名0-17岁毛利人及其父母进行了一项队列研究。贝叶斯片断指数模型估算了儿童首次遭受虐待的时间风险。该分析使用了来自儿童保护、医院、死亡率和警方记录的数据,并特别关注与父母因酗酒住院或使用精神健康/成瘾服务事件相关的风险。父母和毛利人(0-17 岁)的潜在混杂因素都包括在内。我们计算了人口可归因部分,以估计2017年可归因于酒精的虐待病例比例:结果显示,父母严重酗酒的毛利青少年遭受虐待的风险增加了65%。我们估计,在毛利人中,17%经证实的虐待儿童事件可归因于父母酗酒:讨论与结论:父母酗酒或严重酗酒是毛利人虐待儿童的一个危险因素。毛利人的酒精消费和伤害是更广泛的不平等的表现,除其他外,这与殖民化的持续影响以及酒精销售监管方面的差距有关。
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引用次数: 0
Exposure to parental problem drinking during adolescence and symptoms of depression and anxiety in young adulthood: A Swedish national cohort study 青少年时期父母酗酒与青少年成年后的抑郁和焦虑症状:瑞典全国队列研究。
IF 3 3区 医学 Q2 SUBSTANCE ABUSE Pub Date : 2024-07-19 DOI: 10.1111/dar.13910
Sara Brolin Låftman, Viveca Östberg, Joakim Wahlström, Mats Ramstedt, Jonas Raninen

Introduction

Previous research has shown associations between parental problem drinking and adverse mental health outcomes in children. However, while many studies assess parental alcohol problems based on clinical measures, longitudinal studies that investigate the impact of potentially less severe levels of parental alcohol problems are scarce. The aim of this study was to examine if the existence and severity of child-reported parental problem drinking in adolescence is associated with symptoms of depression and anxiety in young adult men and women.

Methods

Data was obtained from the Swedish national cohort study Futura01, including 3143 participants born in 2001 who were surveyed in 2017 (age 15–16) and 2022 (age 20–21). Parental problem drinking was measured at age 15–16 with the short version of The Children of Alcoholics Screening Test. Depression and anxiety symptoms were measured at age 20–21 with the Patient Health Questionnaire-4. Registry information on gender, parental education and parental country of birth were included as covariates.

Results

The results demonstrated an exposure-response pattern, with greater severity of parental problem drinking associated with an increased probability of reporting depression and anxiety symptoms 5 years later. The association between parental problem drinking and subsequent depression symptoms was however present only in females.

Discussion and Conclusions

Adolescents exposed to parental problem drinking have elevated risks of long-term adverse mental health. These risks increase with greater severity of parental problem drinking. It is thus crucial with efforts preventing parental problem drinking and efforts promoting health among children and adolescents who are exposed.

导言:以往的研究表明,父母酗酒问题与儿童的不良心理健康结果之间存在关联。然而,虽然许多研究都是根据临床测量来评估父母的酗酒问题,但很少有纵向研究来调查父母酗酒问题的潜在较轻程度所产生的影响。本研究旨在探讨儿童报告的父母青少年时期酗酒问题的存在和严重程度是否与青年男女的抑郁和焦虑症状有关:数据来自瑞典国家队列研究Futura01,包括3143名2001年出生的参与者,他们分别在2017年(15-16岁)和2022年(20-21岁)接受了调查。在 15-16 岁时,使用酗酒者子女筛查测试简版对父母的酗酒问题进行了测量。20-21岁时的抑郁和焦虑症状通过《患者健康问卷-4》进行测量,性别、父母受教育程度和父母出生国等登记信息作为协变量被纳入其中:结果:研究结果显示了一种暴露-反应模式,父母酗酒问题越严重,5 年后报告抑郁和焦虑症状的概率越高。然而,父母酗酒与随后的抑郁症状之间的关联仅出现在女性身上:讨论与结论:父母酗酒对青少年的心理健康造成长期不利影响的风险较高。这些风险随着父母酗酒问题的严重程度而增加。因此,预防父母问题饮酒和促进接触问题饮酒的儿童和青少年的健康至关重要。
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引用次数: 0
The role of on-site drug analysis within supervised injecting facilities: A case presentation of an adverse event highlighting need 现场药物分析在受监督注射机构中的作用:不良事件案例介绍,凸显需求。
IF 3 3区 医学 Q2 SUBSTANCE ABUSE Pub Date : 2024-07-19 DOI: 10.1111/dar.13909
Robert Page, Marianne Jauncey, Jonathan Brett, Will Wood, Amanda Roxburgh

Introduction

The Sydney Medically Supervised Injecting Centre provides a safe, non-judgemental space where people can inject pre-obtained substances under the supervision of trained staff. This article describes an unusual incident occurring at the Medically Supervised Injecting Centre in January 2023.

Case Presentation

Two regular male clients attending the Medically Supervised Injecting Centre injected a substance they believed to be cocaine. Both clients experienced adverse reactions; one was transported to hospital, while the other became extremely distressed and agitated. Paraphernalia sent for testing returned a result of tiletamine (a dissociative used in veterinary medicine) and no cocaine, 30 h after the incident.

Discussion and Conclusions

Where substances are novel or unknown, adverse events are often unexpected and may be more difficult to prepare for. Substance-induced acute agitation can be alarming and hazardous for people consuming drugs and those around them and may pose challenges for staff. There is a substantial evidence base for the benefits of on-site drug analysis and drug checking in reducing harms related to drug use, and in enhancing drug market monitoring. This incident was successfully managed by Medically Supervised Injecting Centre and hospital staff, with no major consequence, however clinical management could have been improved using point of care drug testing.

简介:悉尼医疗监督注射中心为人们提供了一个安全、不受评判的空间,人们可以在训练有素的工作人员监督下注射预先获得的物质。本文描述了 2023 年 1 月在医疗监督注射中心发生的一起不寻常事件:两名经常光顾医疗监督注射中心的男性客户注射了一种他们认为是可卡因的物质。两名客户都出现了不良反应;其中一人被送往医院,另一人则变得极度痛苦和焦躁。事件发生 30 小时后,送去检测的用具检测结果为瓦他敏(一种用于兽医的解离剂),没有可卡因:如果使用的物质是新的或未知的,不良事件往往会出乎意料,而且可能更难防范。药物诱发的急性躁动可能会让吸毒者及其周围的人感到震惊和危险,也可能会给工作人员带来挑战。有大量证据表明,现场药物分析和药物检查可减少与吸毒有关的危害,并加强对毒品市场的监控。医疗监督注射中心和医院工作人员成功地处理了这一事件,没有造成重大后果,但临床管理本可以通过使用护理点药物检测加以改进。
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引用次数: 0
A case of severe and prolonged γ-hydroxybutyrate (GHB) withdrawal syndrome successfully managed with a slow benzodiazepine and baclofen taper. 一例严重且持续时间较长的γ-羟丁酸(GHB)戒断综合征病例,通过缓慢减少苯二氮卓类药物和巴氯芬的用量成功治愈。
IF 3 3区 医学 Q2 SUBSTANCE ABUSE Pub Date : 2024-07-17 DOI: 10.1111/dar.13911
Rachit Gupta, Greta Moon, Yvonne Bonomo, Adam Pastor

Introduction: γ-hydroxybutyrate (GHB) is a GABA-B agonist that rapidly produces effects that are likened to both alcohol and MDMA/ecstasy. GHB use can lead to neuroadaptation with a characteristic withdrawal syndrome. There is currently a paucity of data on the progression of GHB withdrawal, however, due to the drug's short half-life it is generally considered to be typically 5-7 days, although some cases can be severe and complicated by life threatening delirium. Here, we present a case of severe GHB withdrawal, which recurred on multiple occasions over 56 days, despite initial clinical stabilisation on each occasion and toxicological evidence of abstinence from GHB between episodes.

Case presentation: A male patient in his 30s presented with agitated delirium on a background of severe GHB use disorder with a 15-year history of daily high dose GHB use. Following 3 hospital admissions over 8 weeks, all requiring intravenous sedation and tracheal intubation, the patient's withdrawal delirium was successfully treated with a slow benzodiazepine and baclofen wean over a period of 6 months. Relapse to GHB use between hospitalisations was excluded toxicologically via blood analysis performed at an institute of forensic pathology.

Discussion and conclusions: This case highlights that GHB withdrawal can be more prolonged than previously reported in the literature and in some cases may require slow and prolonged tapering of treatment to prevent re-emergence of delirium. Similar to previous case reports, benzodiazepines and GABA-B receptor agonists appear to be appropriate drug classes to manage GHB withdrawal.

导言:γ-羟丁酸(GHB)是一种 GABA-B 激动剂,能迅速产生类似酒精和摇头丸/摇头丸的效果。使用 GHB 可导致神经适应,并伴有特征性戒断综合征。目前有关 GHB 戒断进展的数据还很少,但由于该药物的半衰期很短,一般认为通常为 5-7 天,不过有些病例可能很严重,并伴有危及生命的谵妄。在此,我们介绍了一例严重的伽马--羟丁酸(GHB)戒断病例,尽管患者每次戒断后的临床症状都初步稳定,而且毒理学证据表明患者在两次发作之间戒断了伽马--羟丁酸(GHB),但患者在 56 天内仍多次复发:病例介绍:一名 30 多岁的男性患者在严重伽马--羟丁酸使用障碍的背景下出现躁动性谵妄,并有 15 年的每日大剂量伽马--羟丁酸使用史。经过 8 周的 3 次入院治疗(均需要静脉镇静和气管插管),患者的戒断性谵妄在 6 个月的时间里通过缓慢的苯二氮卓和巴氯芬断药治疗获得了成功。通过法医病理学研究所进行的血液分析,从毒理学角度排除了患者在两次住院之间再次使用伽马--羟丁酸的可能性:本病例突出表明,伽马--羟丁酸(GHB)戒断的时间可能比以前文献报道的更长,在某些情况下可能需要缓慢、长时间地减少治疗,以防止谵妄再次出现。与之前的病例报告类似,苯二氮卓类药物和 GABA-B 受体激动剂似乎是治疗 GHB 戒断的适当药物类别。
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Drug and alcohol review
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