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RNA-seq Reveals the Increased Risk of Heart and Cardiovascular Disease by SARS-CoV-2 Infection rna测序揭示SARS-CoV-2感染增加心脏和心血管疾病的风险
YingQiao Wang, R. Wen, Mingcong Li
As of late 2020, much is still unknown about the novel SARS-CoV-2 virus, including what health risks could be present for current patients. We know that while being infected with the disease, patients are struck with many respiratory issues. However, little is known about the long-term effects COVID-19 survivors could be affected by. Using differential expression analysis, we identified several differentially expressed genes in COVID-19 positive patients that indicate an increase in the risk for heart disease in these patients - APOL3, KLF15, and CD163. These genes indicate an increase of risk for cardiovascular disease through increased apolipoprotein levels, decreased negative regulators for risk factors, and increased inflammation and infection.
截至2020年底,人们对新型SARS-CoV-2病毒仍有很多未知之处,包括当前患者可能面临的健康风险。我们知道,在感染这种疾病的同时,患者会出现许多呼吸问题。然而,人们对COVID-19幸存者可能受到的长期影响知之甚少。通过差异表达分析,我们在COVID-19阳性患者中发现了几个差异表达基因——APOL3、KLF15和CD163,这些基因表明这些患者患心脏病的风险增加。这些基因通过增加载脂蛋白水平、减少危险因素的负调节因子以及增加炎症和感染,表明心血管疾病的风险增加。
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引用次数: 0
Data Augmentation to Improve the diagnosis of Melanoma using Convolutional Neural Networks 使用卷积神经网络提高黑色素瘤诊断的数据增强
Yifan Yang
Early diagnosis of melanoma can substantially increase patient survival rate. Currently, dermoscopy is the dominant approach for clinical detection, but this method requires interaction with a trained clinical professional resulting in a financial burden which is a major limiting factor for many patients, especially those in remote and rural locations. It has been proposed that deep convolutional neural networks (CNNs) could allow an automated approaches for diagnosis of melanoma. However, there has been limited work regarding the use of CNNs to diagnose melanoma due to a limited amount of labelled training data available, a major limiting factor for the implementation of CNNs. This study utilises data augmentation techniques to improve CNN performance for diagnosis of melanoma, resulting a 12.4% increase in validation accuracy despite the collection of no additional training data.
黑色素瘤的早期诊断可以大大提高患者的存活率。目前,皮肤镜检查是临床检测的主要方法,但这种方法需要与训练有素的临床专业人员互动,导致经济负担,这是许多患者,特别是偏远和农村地区患者的主要限制因素。有人提出,深度卷积神经网络(cnn)可以实现黑色素瘤诊断的自动化方法。然而,由于可用的标记训练数据数量有限,使用cnn诊断黑色素瘤的工作有限,这是cnn实施的主要限制因素。本研究利用数据增强技术来提高CNN诊断黑色素瘤的性能,在没有收集额外训练数据的情况下,验证准确率提高了12.4%。
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引用次数: 1
Polite Zebra Crossing Driver Reminding System Design 礼貌斑马线司机提醒系统设计
Nan Fang, Zhiyong Zhang, Bingcan Xia, Zichen Yao
In order to effectively avoid the occurrence of traffic accidents, and ensure the safety of pedestrians, the paper proposes an intelligent method of identifying zebra crossings. First, we collect the road condition information of the automobile data recorder, analyze digital image and process identify zebra crossings. We can identify zebra crossing according to the edge detection of canny operator and Hough straight line detection algorithm, and design intelligent voice response reminders according to the recognition. Experiments have proved that under normal lighting conditions, the zebra crossing can be effectively identified and reminded in real time through the driving video, and the misrecognition rate is within 6.5%. This research provides an effective method for the detection of zebra crossings, which guarantees the bilateral safety of pedestrians and drivers to a certain extent, and has important practical significance for promoting harmonious road traffic safety.
为了有效避免交通事故的发生,保证行人的安全,本文提出了一种智能识别斑马线的方法。首先采集汽车数据记录仪的路况信息,对数字图像进行分析,并对斑马线进行处理识别。我们可以根据canny算子的边缘检测和Hough直线检测算法对斑马线进行识别,并根据识别结果设计智能语音响应提醒。实验证明,在正常照明条件下,通过行车视频可以有效识别并实时提醒斑马线,误认率在6.5%以内。本研究为斑马线的检测提供了一种有效的方法,在一定程度上保证了行人和驾驶员的双向安全,对于促进和谐道路交通安全具有重要的现实意义。
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引用次数: 0
A Modified HOG Algorithm based on the Prewitt Operator 基于Prewitt算子的改进HOG算法
Yu Li, Nanxi Huang, Kongling Liu, Hongguan Chen, Ziwei Wang, Juan Yu
The histogram of oriented gradient(HOG) is a feature descriptor used for object detection in the computer vision and image processing, and it is widely used for pedestrian detection. The conspicuous image feature can improve the detective accuracy of the pedestrian detection. In order to improve the conspicuousness of extracted gradient, this paper modifies the gradient extraction operator based on the traditional HOG algorithm. By the tests of different operators, this paper chooses the Prewitt operator to extract the gradient information. Experimental results indicate that the mean and variance of extracted gradient are larger than the gradient of traditional HOG algorithm. The extracted gradient should be generated the conspicuous HOG feature that may improve the performance of pedestrian detection.
定向梯度直方图(HOG)是计算机视觉和图像处理中用于目标检测的一种特征描述符,在行人检测中得到了广泛的应用。明显的图像特征可以提高行人检测的检测精度。为了提高提取梯度的显著性,本文在传统HOG算法的基础上对梯度提取算子进行了改进。通过对不同算子的检验,本文选择Prewitt算子提取梯度信息。实验结果表明,提取的梯度均值和方差均大于传统HOG算法的梯度。提取的梯度应生成明显的HOG特征,可以提高行人检测的性能。
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引用次数: 0
Research of Online Hidden Curriculum Based on Bigdate 基于Bigdate的在线隐性课程研究
Zhen-zhi Meng
During the current epidemic, most of the coleges and universities in China and abroad adopted online teaching method instead of traditional face-to-face class, to control the infections and protect the safety of teachers and students. Under current situation, this research applies quantitative research method by online bigdate analizin and inviting 230 college students to participate in a questionnaire survey, aiming to analyse the relationship between online hidden curriculum and the learning tendency of students. Through the research, it has been found that: (1) Online hidden curriculum significantly impact the learning tendency of students in a positive way. With the strengthening of students' understanding of hidden curriculum, their learning tendency will also increase accordingly; (2) The four dimensions, including learning rules and value of online hidden curriculum, learning about teachers, learning to restrain self, and gaining confidence in dialogue shows different effects on learner's learning tendency. In the process of online teaching, various colleges and universities can achieve the purpose of enhancing student's learning tendency by consciously designing hidden curriculum in online courses.
本次疫情期间,国内外高校大多采用网络教学方式,而不是传统的面授教学,以控制感染,保护师生安全。在目前的情况下,本研究采用定量研究的方法,通过网络数据分析,邀请230名大学生参与问卷调查,旨在分析网络隐性课程与学生学习倾向的关系。通过研究发现:(1)网络隐性课程对学生的学习倾向有显著的正向影响。随着学生对隐性课程认识的加强,他们的学习倾向也会相应提高;(2)网络隐性课程的学习规则与价值、对教师的了解、对自我约束的学习、在对话中获得自信四个维度对学习者的学习倾向有不同的影响。在网络教学过程中,各高校可以通过在网络课程中有意识地设计隐性课程来达到提高学生学习倾向的目的。
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引用次数: 0
Common Methods of Image Panoptic Segmentation Based on Deep Learning 基于深度学习的图像全视分割的常用方法
Congcong Wang
In recent years, with the rapid development of deep learning technology and its wide application in the field of computer vision, various image understanding tasks including semantic segmentation and instance segmentation have made great progress, and people's further demand for image understanding has spawned a more comprehensive task image panoptic segmentation. Image panoptic segmentation can be seen as the combination of semantic segmentation and instance segmentation. For uncountable object categories (called stuff), the pixel category is distinguished. For countable object categories (called things), not only the semantic category of the target is recognized, but also each instance is distinguished. This task can provide more comprehensive scene information, and can be widely used in the understanding of various natural scenes. This paper investigate the commonly used panoptic segmentation methods, including the basic shared feature extraction method, the information combination method between semantic segmentation and instance segmentation sub-tasks, and the learnable method to remove the overlap between instances. This paper also summarize the commonly used panoptic segmentation datasets and the evaluation metrics, then the experimental performance evaluation results of various methods on commonly used datasets are showed. Finally, this paper summarize the general direction of panoptic segmentation, and predict the future research direction.
近年来,随着深度学习技术的快速发展及其在计算机视觉领域的广泛应用,包括语义分割和实例分割在内的各种图像理解任务都取得了长足的进步,人们对图像理解的进一步需求催生了更全面的任务图像全景分割。图像全光学分割可以看作是语义分割和实例分割的结合。对于不可数的对象类别(称为物质),区分像素类别。对于可数的对象类别(称为事物),不仅要识别目标的语义类别,而且要区分每个实例。该任务可以提供更全面的场景信息,可以广泛应用于对各种自然场景的理解。本文研究了常用的泛视分割方法,包括基本共享特征提取方法、语义分割子任务与实例分割子任务的信息组合方法以及去除实例间重叠的可学习方法。总结了常用的全光分割数据集和评价指标,给出了各种方法在常用数据集上的实验性能评价结果。最后,对全视分割的研究方向进行了总结,并对未来的研究方向进行了展望。
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引用次数: 0
Social Media Opinion Leader Identification Based on Sentiment Analysis 基于情感分析的社交媒体意见领袖识别
Yi Zhai, Zhijian Wang, Haoming Zeng, Zhensheng Hu
Growing number of enterprises nowadays are pursuing online marketing strategies, with their eyes focusing on the effectiveness of opinion leader value-creation on social media platform. Therefore, how to accurately identify opinion leaders on social media platforms is of great significance. The emotional value generated by communication between opinion leaders and fans will have a significant impact on the potential consumption behavior of fans. Most of the existing research on opinion leader identification is to establish models based on the existing indicator data of the platform, without taking the value of emotional communication into account. This paper proposes a social media opinion leader identification model based on online comment sentiment analysis. We first crawl online comments, then analyze the text data characteristics, establish emotional indicators of different attributes, calculate the sentiment value of the text data, and finally use artificial neural network technology to train to form an opinion leader recognition model. The experimental results show that emotional communication is a very important factor in opinion leader identification, and the proposed model can identify opinion leaders more accurately.
现在越来越多的企业都在追求网络营销策略,他们关注的是意见领袖在社交媒体平台上价值创造的有效性。因此,如何准确识别社交媒体平台上的意见领袖具有重要意义。意见领袖与粉丝之间的沟通所产生的情感价值会对粉丝的潜在消费行为产生重大影响。现有的意见领袖识别研究大多是基于平台已有的指标数据建立模型,没有考虑到情感沟通的价值。本文提出了一种基于网络评论情感分析的社交媒体意见领袖识别模型。我们首先抓取网络评论,然后分析文本数据特征,建立不同属性的情感指标,计算文本数据的情感值,最后利用人工神经网络技术进行训练,形成意见领袖识别模型。实验结果表明,情绪沟通是意见领袖识别的重要因素,该模型能够更准确地识别意见领袖。
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引用次数: 1
Application of an improved empirical mode decomposition algorithm in the feature extraction of blood pressure signal in salt-sensitive rats 改进经验模态分解算法在盐敏感大鼠血压信号特征提取中的应用
Haofan Wu, Jinbo Yang, Yili Zhu, Xinbao Wang, Zhaoqian Luo, Yating Xiao
Analyzing the blood pressure signal of salt-sensitive rats can provide important information for the study of blood pressure changes caused by human salt sensitivity. The blood pressure signal usually contains noise. In order to extract a more pure blood pressure signal, this paper uses an improved EMD algorithm based on noise statistical features. First, emd is applied to the original signal, and the high frequency noise except the heart rate will be randomly sorted. Then this paper add this signal to the original noise and calculate the average value, use the result as the new noise signal to sum the original real signal, and then do EMD. This algorithm effectively reduces the power of noise. The simulation results show that this method can effectively extract the blood pressure signal of salt-sensitive (SS) rats. Under the high and low salt diet, the changes in blood pressure of the rats are in line with medical laws.
分析盐敏感大鼠的血压信号,可以为研究人体盐敏感引起的血压变化提供重要信息。血压信号通常含有噪声。为了提取更纯净的血压信号,本文采用了一种改进的基于噪声统计特征的EMD算法。首先对原始信号进行emd处理,对除心率外的高频噪声进行随机排序。然后将该信号与原始噪声相加并计算平均值,将其作为新的噪声信号与原始真实信号求和,然后进行EMD。该算法有效地降低了噪声的影响。仿真结果表明,该方法可以有效地提取盐敏感大鼠的血压信号。在高盐和低盐饮食下,大鼠血压的变化符合医学规律。
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引用次数: 0
The Goals of Teaching C Language Programming in Higher Vocational Education 高职C语言程序设计教学的目标
Jian Liu
C language programming which was an ordinary course for computer major was arranged both in higher vocational college and general university. The goals of teaching it should be different, because the points of higher vocational education and higher education were different. Many teachers in higher vocational college did not pay attention to different goals due to not distinguishing the difference. There are lots of papers on studying the patterns of teaching this course, but there is few paper on studying the goals of teaching it. This paper focused on explaining the goals of teaching C programming in higher vocational education, such as spirit of team work, communication with machine, good habit, base of major courses, training thinking.
C语言程序设计是高职院校和普通高校计算机专业的一门普通课程。由于高职教育与高等教育的着眼点不同,高职教育的教学目标应该有所不同。许多高职院校教师由于没有区分不同的目标而不重视不同的目标。研究这门课教学模式的论文很多,但研究这门课教学目标的论文却很少。本文着重阐述了高职C程序设计教学的目标,如团队合作精神、与机器的沟通、良好的习惯、专业课程基础、训练思维等。
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引用次数: 0
Research on Early Screening of Lung Cancer Based on Artificial Intelligence 基于人工智能的肺癌早期筛查研究
Liusheng Wu, Xiaoqiang Li
With the development of computer technology, electronic engineering, statistics and other disciplines, artificial intelligence (AI) has made breakthroughs in the medical field, and intelligent diagnosis and treatment has become an important development trend. The core methodological research of AI focuses on machine learning, and machine learning on clinical medicine is the key technology for using medical big data. Lung cancer is the malignant tumor with the highest morbidity and mortality in the world. Early CT screening can reduce the mortality of lung cancer patients. However, there are currently a large number of screenings, a large workload of physicians, and a high rate of missed diagnosis. This article explores the use of artificial intelligence (AI) screening for early lung cancer, and discusses the clinical significance of this method in the diagnosis of lung nodules. In lung cancer diagnosis, a lot of work has been done in computer-aided diagnosis, including traditional image processing methods, traditional machine learning methods, deep learning methods, and convolutional neural networks. This article compares and analyzes the output results of the Tumar Deep-Dimensional Lung Nodule Intelligent Diagnosis System and the diagnosis results of the chest C-images of the two-person reading patient, and studies the important value of artificial intelligence in the early screening of lung cancer.
随着计算机技术、电子工程、统计学等学科的发展,人工智能(AI)在医疗领域取得突破,智能化诊疗成为重要发展趋势。人工智能的核心方法论研究集中在机器学习上,而临床医学上的机器学习是医疗大数据应用的关键技术。肺癌是世界上发病率和死亡率最高的恶性肿瘤。早期CT筛查可以降低肺癌患者的死亡率。但目前筛查量大,医生工作量大,漏诊率高。本文探讨利用人工智能(AI)筛查早期肺癌,并探讨该方法在肺结节诊断中的临床意义。在肺癌诊断中,计算机辅助诊断已经做了很多工作,包括传统的图像处理方法、传统的机器学习方法、深度学习方法、卷积神经网络等。本文将Tumar深维肺结节智能诊断系统输出结果与双人阅读患者胸部c -像诊断结果进行对比分析,研究人工智能在肺癌早期筛查中的重要价值。
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引用次数: 0
期刊
Proceedings of the 2021 International Conference on Bioinformatics and Intelligent Computing
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