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Acute gallbladder pathologies beyond uncomplicated cholecystitis. 急性胆囊病变超越单纯的胆囊炎。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-08-01 Epub Date: 2025-06-10 DOI: 10.1007/s10140-025-02355-0
William Wei, Gavin Sugrue, Shamir Rai, Nicolas Murray

The gallbladder can be affected by various acute conditions beyond uncomplicated cholecystitis, with the prevalence of gallstones having risen over the past three decades. Management of biliary diseases is complex and necessitates careful case-by-case consideration. Radiologic imaging plays a crucial role in the evaluation, diagnosis, and management planning of biliary pathologies. This review explores acute gallbladder conditions such as simple cholecystitis, gangrenous cholecystitis, emphysematous cholecystitis, hemorrhagic cholecystitis, perforated cholecystitis, gallbladder fistulas, gallstone ileus, Bouveret syndrome, Mirizzi syndrome, gallbladder herniation, volvulus, trauma, pseudoaneurysm, portal venous thrombosis, and gallbladder carcinoma. It highlights the utility of various imaging modalities including ultrasound, CT, dual-energy CT, MRI, and MRCP in diagnosing these conditions. Advancements in imaging techniques have enhanced the ability to detect and characterize gallbladder diseases, facilitating timely surgical interventions and improving patient outcomes. This review emphasizes the importance of close collaboration between radiologists and clinicians to optimize diagnosis and management strategies, underscoring the indispensable role of radiologic imaging in modern medicine.

胆囊可以受到各种急性条件的影响,而不是单纯的胆囊炎,在过去的三十年中,胆结石的患病率有所上升。胆道疾病的管理是复杂的,需要仔细的个案考虑。放射影像在胆道疾病的评估、诊断和治疗计划中起着至关重要的作用。这篇综述探讨了急性胆囊疾病,如单纯性胆囊炎、坏疽性胆囊炎、气肿性胆囊炎、出血性胆囊炎、穿孔性胆囊炎、胆囊瘘、胆石性肠梗阻、Bouveret综合征、Mirizzi综合征、胆囊疝、肠回、创伤、假性动脉瘤、门静脉血栓形成和胆囊癌。它强调了各种成像方式的效用,包括超声、CT、双能CT、MRI和MRCP在诊断这些疾病中的作用。影像技术的进步提高了检测和表征胆囊疾病的能力,促进了及时的手术干预,改善了患者的预后。这篇综述强调放射科医生和临床医生之间密切合作的重要性,以优化诊断和管理策略,强调放射成像在现代医学中不可或缺的作用。
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引用次数: 0
Fine-tuned large Language model for extracting newly identified acute brain infarcts based on computed tomography or magnetic resonance imaging reports. 基于计算机断层扫描或磁共振成像报告,用于提取新识别的急性脑梗死的微调大型语言模型。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-08-01 Epub Date: 2025-06-02 DOI: 10.1007/s10140-025-02354-1
Nana Fujita, Koichiro Yasaka, Shigeru Kiryu, Osamu Abe

Purpose: This study aimed to develop an automated early warning system using a large language model (LLM) to identify acute to subacute brain infarction from free-text computed tomography (CT) or magnetic resonance imaging (MRI) radiology reports.

Methods: In this retrospective study, 5,573, 1,883, and 834 patients were included in the training (mean age, 67.5 ± 17.2 years; 2,831 males), validation (mean age, 61.5 ± 18.3 years; 994 males), and test (mean age, 66.5 ± 16.1 years; 488 males) datasets. An LLM (Japanese Bidirectional Encoder Representations from Transformers model) was fine-tuned to classify the CT and MRI reports into three groups (group 0, newly identified acute to subacute infarction; group 1, known acute to subacute infarction or old infarction; group 2, without infarction). The training and validation processes were repeated 15 times, and the best-performing model on the validation dataset was selected to further evaluate its performance on the test dataset.

Results: The best fine-tuned model exhibited sensitivities of 0.891, 0.905, and 0.959 for groups 0, 1, and 2, respectively, in the test dataset. The macrosensitivity (the average of sensitivity for all groups) and accuracy were 0.918 and 0.923, respectively. The model's performance in extracting newly identified acute brain infarcts was high, with an area under the receiver operating characteristic curve of 0.979 (95% confidence interval, 0.956-1.000). The average prediction time was 0.115 ± 0.037 s per patient.

Conclusion: A fine-tuned LLM could extract newly identified acute to subacute brain infarcts based on CT or MRI findings with high performance.

目的:本研究旨在开发一种使用大语言模型(LLM)的自动预警系统,从自由文本计算机断层扫描(CT)或磁共振成像(MRI)放射学报告中识别急性至亚急性脑梗死。方法:本回顾性研究共纳入5573例、1883例和834例患者(平均年龄67.5±17.2岁;男性2831人),验证(平均年龄61.5±18.3岁;994名男性),平均年龄66.5±16.1岁;488名男性)数据集。LLM(日本双向编码器表示从变压器模型)进行微调,将CT和MRI报告分为三组(0组,新发现的急性至亚急性梗死;1组,已知急性至亚急性梗死或陈旧性梗死;第二组,无梗死)。训练和验证过程重复15次,选择在验证数据集上表现最好的模型,进一步评估其在测试数据集上的性能。结果:在测试数据集中,对于第0、1和2组,最佳微调模型的灵敏度分别为0.891、0.905和0.959。宏观灵敏度(各组灵敏度平均值)和准确度分别为0.918和0.923。该模型对新识别急性脑梗死的提取性能较高,受试者工作特征曲线下面积为0.979(95%置信区间为0.956 ~ 1.000)。平均预测时间为0.115±0.037 s /例。结论:调整后的LLM可以根据CT或MRI的表现高效提取新发现的急性至亚急性脑梗死。
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引用次数: 0
Yield of MRI in patients with spontaneous deep intracerebral hemorrhage. 自发性深部脑出血患者的MRI表现。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-08-01 Epub Date: 2025-05-20 DOI: 10.1007/s10140-025-02348-z
Hudson McKinney, Bryan A Kirk, Anuj J Jailwala, Aaron McFarlane, Jackson L Sullivan, Raghav Agarwal, Kevin D Hiatt

Purpose: Hypertensive hemorrhage is the most common type of nontraumatic intracerebral hemorrhage (ICH), and it characteristically originates in deep structures, particularly the basal ganglia, internal capsules, thalami, brainstem, and cerebellum. While advanced imaging modalities like MRI can help uncover culprit lesions in cases of unexplained ICH, we hypothesized that the yield of brain MRI would be low in patients with spontaneous deep intracerebral hemorrhage.

Methods: With IRB approval, we retrospectively reviewed cases of deep ICH at a single tertiary care academic center over a 5-year period and excluded cases with a known cause for hemorrhage. Patient history and demographics, initial blood pressure, and the results of the initial noncontrast head CT and subsequent imaging studies were recorded.

Results: 222 patients met study inclusion criteria, with a median age of 67 and 43.2% female sex. 188 patients (84.7%) had a history of hypertension, while 14 (6.3%) had a urine drug screen positive for cocaine or amphetamines during their hospital admission. The majority of hemorrhages were centered in the basal ganglia or internal capsules (116, 52.3%). Brain MRI was obtained for 120 (54.1%) of cases at a median interval of 0.97 days following the initial head CT, and of these studies, 85 (70.8%) included postcontrast imaging. Only 1 MRI study (0.8%) identified a culprit lesion adjacent to a cerebellar hematoma, which was later found to represent a pilocytic astrocytoma. 33.8% of patients overall met the modified Hong Kong Rule. Of the 77 MRIs performed in patients not meeting the modified Hong Kong Rule, 0 revealed a culprit lesion.

Conclusion: Brain MRI obtained in the acute evaluation of patients with spontaneous deep intracerebral hemorrhage rarely uncovers a culprit lesion. Routine ordering of MRI in this cohort should be reconsidered, particularly in patients not meeting the modified Hong Kong Rule.

目的:高血压出血是最常见的非外伤性脑出血(ICH)类型,其特征起源于深部结构,特别是基底节区、内囊、丘脑、脑干和小脑。虽然MRI等先进的成像方式可以帮助发现原因不明的脑出血病例的罪魁祸首病变,但我们假设自发性深部脑出血患者的脑MRI的产出率很低。方法:经IRB批准,我们回顾性分析了一个三级医疗学术中心5年来的深部脑出血病例,排除了已知出血原因的病例。记录患者的病史和人口统计、初始血压、初始非对比头部CT和随后的影像学检查结果。结果:222例患者符合研究纳入标准,中位年龄67岁,女性43.2%。188例患者(84.7%)有高血压病史,14例患者(6.3%)在入院期间尿液可卡因或安非他明药物筛查呈阳性。出血主要集中在基底节区或内囊区(116,52.3%)。120例(54.1%)患者在首次头部CT后的中位间隔0.97天内进行了脑部MRI检查,其中85例(70.8%)患者进行了对比后成像。只有1项MRI研究(0.8%)发现了小脑血肿附近的罪魁祸首病变,后来发现该病变代表毛细胞星形细胞瘤。33.8%的病人符合修订后的香港规则。在不符合修改后的香港规则的患者中进行的77次核磁共振检查中,0次发现了罪魁祸首病变。结论:自发性深部脑出血患者的急性评价中,脑MRI很少能发现病灶。应重新考虑该队列的常规MRI排序,特别是不符合修改后的香港规则的患者。
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引用次数: 0
Predictors of diagnostic errors in computed tomography interpretation by emergency physicians leading to changes in clinical management in the emergency department. 急诊医生计算机断层扫描诊断错误导致急诊科临床管理改变的预测因素
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-08-01 Epub Date: 2025-06-23 DOI: 10.1007/s10140-025-02357-y
Naoaki Shibata, Takafumi Yonemitsu, Nozomu Shima, Yuichi Miyake, Tomoya Fukui, Junya Fuchigami, Akira Ikoma, Tetsuo Sonomura, Shigeaki Inoue

Purpose: The use of computed tomography (CT) in the emergency department (ED) has been increasing due to its diagnostic value for emergency physicians (EPs). This study aimed to determine the predictors of EP interpretation errors (IEs) on CT scans leading to change in clinical management (IECM) in both endogenous and exogenous ED visits.

Methods: This single-center, retrospective cohort study included patients with consecutive ED visits initially managed by EPs at our institution over 6 months. Patients who did not undergo CT imaging and presented with cardiopulmonary arrest upon arrival were excluded. CT images were interpreted by emergency radiologists immediately after acquisition, and IEs were identified. The primary outcome was IECM, determined by reference to the clinical management decisions made by EPs. A multivariate analysis was performed to determine the independent predictors of IECM.

Results: Among the 2,037 patients, 158 (8%) had IEs, whereas 52 (3%) had IECM. Multisite CT imaging was the strongest independent predictor for both IECM (OR: 2.25, 95% CI: 1.21-4.19, P = 0.011) and IEs (OR: 2.32, 95% CI: 1.61-3.36, P < 0.001). Other predictors of IECM were prolonged ED stay and night-time ED visits as clinical factors. Additional predictors of overall IEs were contrast-enhanced CT and abdominopelvic CT as radiological factors.

Conclusion: Multisite CT imaging, which involve multiple organs and extensive diagnostic information, significantly increases the likelihood of misinterpretation, leading to change in clinical management by EPs.

目的:计算机断层扫描(CT)在急诊科(ED)的应用越来越多,因为它对急诊医生(EPs)的诊断价值。本研究旨在确定内源性和外源性ED就诊时CT扫描EP解释错误(IEs)导致临床管理改变(IECM)的预测因素。方法:这项单中心、回顾性队列研究纳入了在我院连续就诊6个月以上的患者,这些患者最初是由急诊医生管理的。未接受CT成像且到达时出现心肺骤停的患者被排除在外。CT图像在采集后立即由急诊放射科医生进行解读,并确定病灶。主要结局是IECM,由EPs的临床管理决策决定。进行多变量分析以确定IECM的独立预测因子。结果:在2037例患者中,158例(8%)有IEs, 52例(3%)有IECM。多部位CT成像是IECM (OR: 2.25, 95% CI: 1.21-4.19, P = 0.011)和IEs (OR: 2.32, 95% CI: 1.61-3.36, P)最重要的独立预测因子。结论:多部位CT成像涉及多器官和广泛的诊断信息,显著增加误解的可能性,导致EPs临床管理的改变。
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引用次数: 0
Preoperative intestine-to-liver CT ratio: useful predictor of resection in strangulated obstruction. 术前肠-肝CT比值:预测绞窄性梗阻切除的有用指标。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-08-01 Epub Date: 2025-07-16 DOI: 10.1007/s10140-025-02369-8
Seiichiro Fujishima, Hironori Tsujimoto, Yoshihisa Yaguchi, Hiroyuki Horiguchi, Keita Kouzu, Yusuke Ishibashi, Yujiro Itazaki, Takafumi Suzuki, Naoyuki Uehata, Risa Kariya, Asuma Ide, Hiroshi Shinmoto, Hideki Ueno

Background: Prompt diagnosis of strangulated bowel obstruction (SBO) is critical because delayed recognition can lead to life-threatening complications. This study assessed whether the intestinal-to-liver CT attenuation value ratio-a comparison of ischemic bowel-wall enhancement to liver enhancement-can predict the need for intestinal resection in SBO patients.

Materials and methods: We retrospectively analyzed 52 patients who underwent emergency surgery for suspected SBO from 2014 to 2021. Of these, 35 required intestinal resection due to irreversible ischemia (resection group), while 17 did not (no-resection group). Preoperative clinical and imaging findings were compared between groups.

Results: The resection group had a longer time from onset to surgery (p = 0.034) and higher leukocyte counts (p = 0.037). CT values of the poorly enhanced intestinal wall and the intestinal-to-liver attenuation ratio were significantly lower in the resection group (p < 0.0001). Multivariate analysis identified time to surgery (OR 5.08; 95% CI 1.106-23.350; p = 0.037) and CT attenuation ratio (OR 15.50; 95% CI 2.622-91.686; p = 0.0025) as independent predictors of resection. When stratified by the median ratio cutoff (< 0.40 vs. ≥ 0.40), resection rates were 92% and 44%, respectively (p = 0.0001). Additionally, CT attenuation ratio had the diagnostic performance (AUROC 0.886; Youden index 0.736; sensitivity 97.1% and specificity 76.5%.) CONCLUSION: An intestinal-to-liver CT attenuation ratio below 0.40 is a strong predictor of intestinal ischemia requiring resection in SBO patients.

背景:及时诊断绞窄性肠梗阻(SBO)至关重要,因为延迟识别可能导致危及生命的并发症。本研究评估肠-肝CT衰减值比值(缺血性肠壁增强与肝脏增强的比较)是否可以预测SBO患者是否需要肠切除术。材料和方法:我们回顾性分析了2014年至2021年因疑似SBO接受急诊手术的52例患者。其中,35例因不可逆缺血需要切除肠道(切除组),17例不需要切除(未切除组)。比较两组术前临床及影像学表现。结果:切除组从发病到手术时间较长(p = 0.034),白细胞计数较高(p = 0.037)。切除组增强不良的肠壁CT值及肠肝衰减比明显降低(p
{"title":"Preoperative intestine-to-liver CT ratio: useful predictor of resection in strangulated obstruction.","authors":"Seiichiro Fujishima, Hironori Tsujimoto, Yoshihisa Yaguchi, Hiroyuki Horiguchi, Keita Kouzu, Yusuke Ishibashi, Yujiro Itazaki, Takafumi Suzuki, Naoyuki Uehata, Risa Kariya, Asuma Ide, Hiroshi Shinmoto, Hideki Ueno","doi":"10.1007/s10140-025-02369-8","DOIUrl":"10.1007/s10140-025-02369-8","url":null,"abstract":"<p><strong>Background: </strong>Prompt diagnosis of strangulated bowel obstruction (SBO) is critical because delayed recognition can lead to life-threatening complications. This study assessed whether the intestinal-to-liver CT attenuation value ratio-a comparison of ischemic bowel-wall enhancement to liver enhancement-can predict the need for intestinal resection in SBO patients.</p><p><strong>Materials and methods: </strong>We retrospectively analyzed 52 patients who underwent emergency surgery for suspected SBO from 2014 to 2021. Of these, 35 required intestinal resection due to irreversible ischemia (resection group), while 17 did not (no-resection group). Preoperative clinical and imaging findings were compared between groups.</p><p><strong>Results: </strong>The resection group had a longer time from onset to surgery (p = 0.034) and higher leukocyte counts (p = 0.037). CT values of the poorly enhanced intestinal wall and the intestinal-to-liver attenuation ratio were significantly lower in the resection group (p < 0.0001). Multivariate analysis identified time to surgery (OR 5.08; 95% CI 1.106-23.350; p = 0.037) and CT attenuation ratio (OR 15.50; 95% CI 2.622-91.686; p = 0.0025) as independent predictors of resection. When stratified by the median ratio cutoff (< 0.40 vs. ≥ 0.40), resection rates were 92% and 44%, respectively (p = 0.0001). Additionally, CT attenuation ratio had the diagnostic performance (AUROC 0.886; Youden index 0.736; sensitivity 97.1% and specificity 76.5%.) CONCLUSION: An intestinal-to-liver CT attenuation ratio below 0.40 is a strong predictor of intestinal ischemia requiring resection in SBO patients.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":" ","pages":"581-589"},"PeriodicalIF":1.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12328548/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Identifying key CT features and clinical variables for predicting operative management of left ventricular assist device (LVAD) driveline infections. 确定预测左心室辅助装置(LVAD)传动系统感染手术处理的关键CT特征和临床变量。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-08-01 Epub Date: 2025-07-08 DOI: 10.1007/s10140-025-02363-0
Mahati Mokkarala, Aravinda Ganapathy, Yuktesh Kalidindi, Chelsea R Schmitt, Mark J Hoegger, Ryan G Short, Demetrios A Raptis, David H Ballard

Purpose: Despite technical advancements in left ventricular assist devices (LVADs), driveline infections (DLIs) remain a common complication evaluated by CT. The purpose of this study was to assess CT imaging features and clinical variables associated with operative versus non-operative management of LVAD DLIs.

Materials/methods: This study analyzed 129 patients with LVAD driveline infections evaluated using CT. Two radiologists assessed CT scans for superficial and deep soft tissue stranding and fluid collections. Logistic regression was used to identify predictors of operative management using imaging and clinical variables, guided by Akaike information criterion. Results were reported as odds ratios, and Interreader agreement was evaluated using Cohen's Kappa.

Results: Operative management was performed in 46.8% of patients. Positive driveline cultures (94.8% vs. 43.5%, p < 0.001) and new antibiotic use (98.3% vs. 72.7%, p < 0.001) were strongly associated with operative intervention. Mild subcutaneous fat stranding was the most frequent CT finding (62.6% and 66.9% by Readers 1 and 2, respectively), whereas deep fluid collections were rare (4.8-5.6%). Clinical predictors of operative management included new antibiotic use (p = 0.036), positive cultures (p < 0.001), and LVAD type. The resulting model achieved an AUC of 0.851 and overall accuracy of 78.6%. The absence of superficial fat stranding on CT significantly predicted non-operative management (p < 0.001).

Conclusion: Positive driveline cultures, recent antibiotic initiation, and absence of skin or subcutaneous fat stranding on CT were associated with non-operative management in LVAD-related driveline infections. Absence of superficial fat stranding on CT may help distinguish suspected driveline infections that are unlikely to require surgical intervention.

目的:尽管左心室辅助装置(lvad)技术进步,但传动系感染(DLIs)仍然是CT评估的常见并发症。本研究的目的是评估与手术与非手术治疗LVAD直连相关的CT影像特征和临床变量。材料/方法:本研究分析了129例LVAD传动系感染的CT评估。两名放射科医生评估了浅层和深层软组织搁浅和积液的CT扫描结果。以赤池信息标准为指导,采用Logistic回归分析影像学和临床变量,确定手术管理的预测因素。结果以比值比报告,使用Cohen's Kappa评估Interreader一致性。结果:46.8%的患者接受手术治疗。结论:lvad相关的驱动系统感染的非手术治疗与驱动系统培养阳性、近期开始使用抗生素、CT上没有皮肤或皮下脂肪滞留有关。CT上没有浅表脂肪滞留可能有助于区分疑似传动系统感染,这些感染不太可能需要手术干预。
{"title":"Identifying key CT features and clinical variables for predicting operative management of left ventricular assist device (LVAD) driveline infections.","authors":"Mahati Mokkarala, Aravinda Ganapathy, Yuktesh Kalidindi, Chelsea R Schmitt, Mark J Hoegger, Ryan G Short, Demetrios A Raptis, David H Ballard","doi":"10.1007/s10140-025-02363-0","DOIUrl":"10.1007/s10140-025-02363-0","url":null,"abstract":"<p><strong>Purpose: </strong>Despite technical advancements in left ventricular assist devices (LVADs), driveline infections (DLIs) remain a common complication evaluated by CT. The purpose of this study was to assess CT imaging features and clinical variables associated with operative versus non-operative management of LVAD DLIs.</p><p><strong>Materials/methods: </strong>This study analyzed 129 patients with LVAD driveline infections evaluated using CT. Two radiologists assessed CT scans for superficial and deep soft tissue stranding and fluid collections. Logistic regression was used to identify predictors of operative management using imaging and clinical variables, guided by Akaike information criterion. Results were reported as odds ratios, and Interreader agreement was evaluated using Cohen's Kappa.</p><p><strong>Results: </strong>Operative management was performed in 46.8% of patients. Positive driveline cultures (94.8% vs. 43.5%, p < 0.001) and new antibiotic use (98.3% vs. 72.7%, p < 0.001) were strongly associated with operative intervention. Mild subcutaneous fat stranding was the most frequent CT finding (62.6% and 66.9% by Readers 1 and 2, respectively), whereas deep fluid collections were rare (4.8-5.6%). Clinical predictors of operative management included new antibiotic use (p = 0.036), positive cultures (p < 0.001), and LVAD type. The resulting model achieved an AUC of 0.851 and overall accuracy of 78.6%. The absence of superficial fat stranding on CT significantly predicted non-operative management (p < 0.001).</p><p><strong>Conclusion: </strong>Positive driveline cultures, recent antibiotic initiation, and absence of skin or subcutaneous fat stranding on CT were associated with non-operative management in LVAD-related driveline infections. Absence of superficial fat stranding on CT may help distinguish suspected driveline infections that are unlikely to require surgical intervention.</p>","PeriodicalId":11623,"journal":{"name":"Emergency Radiology","volume":" ","pages":"533-543"},"PeriodicalIF":1.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144583413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic accuracy of chest CT for COVID-19 pneumonia in a resource-limited Gaza cohort: a retrospective study of 252 patients. 在资源有限的加沙队列中,胸部CT对COVID-19肺炎的诊断准确性:一项252例患者的回顾性研究
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-08-01 Epub Date: 2025-06-21 DOI: 10.1007/s10140-025-02359-w
Husam H Mansour, Noor Khairiah A Karim, Noor Diyana Osman, Rohayu Hami, Yasser S Alajerami

Purpose: The study aimed to evaluate the diagnostic accuracy of chest CT for COVID-19 pneumonia in resource-limited Gaza. It compared CT performance to RT-PCR and examined how CT severity scores and interobserver agreement influence diagnostic accuracy, reproducibility, and clinical utility for early detection and triage.

Methods: A retrospective analysis was performed on 252 consecutive patients diagnosed with COVID-19 pneumonia between September 2020 and June 2021 at three major governmental hospitals across the Gaza Strip. Chest CT scans were compared to RT-PCR as the gold standard for diagnosis. CT severity scores were calculated using a 25-point system, and interobserver agreement was assessed using kappa statistics. Sensitivity, specificity, and predictive values were calculated for various threshold levels.

Results: Among the 252 patients included in the study, the mean age was 56.81 ± 11.34 years, with 113 males and 139 females. The diagnostic sensitivity of chest CT was 91.4%, with a specificity of 76.4%. The highest accuracy was observed with a severity score threshold of ≥ 15, with a Youden index of 0.630. Interobserver agreement was excellent (kappa = 0.87) for ground-glass opacities and consolidation. The NPV was 71.2%, indicating the need for supplementary RT-PCR testing in low-prevalence cases.

Conclusion: Chest CT is a reliable diagnostic adjunct for COVID-19 pneumonia, especially in Gaza's severely resource-limited setting, where CT was more accessible than RT-PCR. A CT severity score threshold of ≥ 15 offers an optimal balance of sensitivity and specificity. These findings highlight the practical role of CT imaging in pandemic response in resource-constrained environments.

目的:评价资源有限的加沙地区胸部CT对COVID-19肺炎的诊断准确性。它比较了CT表现与RT-PCR,并检查了CT严重程度评分和观察者间的一致性如何影响诊断准确性、可重复性以及早期检测和分诊的临床效用。方法:对2020年9月至2021年6月期间在加沙地带三家主要政府医院连续诊断为COVID-19肺炎的252例患者进行回顾性分析。将胸部CT扫描与RT-PCR作为诊断的金标准进行比较。采用25分制计算CT严重程度评分,采用kappa统计评估观察者间的一致性。对不同阈值水平计算敏感性、特异性和预测值。结果:纳入研究的252例患者平均年龄56.81±11.34岁,其中男性113例,女性139例。胸部CT诊断敏感性为91.4%,特异性为76.4%。严重度评分阈值≥15时准确率最高,约登指数为0.630。观察者间对于毛玻璃混浊和实变的一致性非常好(kappa = 0.87)。NPV为71.2%,表明在低流行病例中需要补充RT-PCR检测。结论:胸部CT是COVID-19肺炎的可靠诊断辅助手段,特别是在加沙严重资源有限的环境中,CT比RT-PCR更容易获得。CT严重性评分阈值≥15提供了敏感性和特异性的最佳平衡。这些发现突出了CT成像在资源受限环境中应对大流行的实际作用。
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引用次数: 0
Wide-Detector CT-Based optimized triple Rule-Out CT angiography for emergency chest pain: reducing contrast and radiation without compromising diagnostic quality. 基于宽探测器CT的优化三重排除CT血管造影用于急诊胸痛:在不影响诊断质量的情况下降低对比度和辐射。
IF 1.3 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-08-01 Epub Date: 2025-05-28 DOI: 10.1007/s10140-025-02351-4
Qiuhua Zhang, Kun Wang, Hong Ren

Background: The triple rule-out computed tomography angiography (TRO-CTA) has recently emerged as a technique that noninvasively evaluates the coronary arteries (CAs), the pulmonary arteries (PAs) and the thoracic aorta (TA).

Objective: To evaluate the feasibility of an optimized scanning protocol to reduce the volume of iodine contrast media (ICM), injection rate, and radiation dose in patients undergoing TRO-CTA.

Methods: Patients undergoing TRO-CTA were assigned to either group A or group B using a 16 cm wide-detector CT. Patients in group A were imaged with a traditional triple scanning protocol with a sequence of the PA, CAs, and TA. Patients in group B were imaged using the modified protocol with scanning sequence of PA, TA, and CAs, ICM of 55 ml, and injection rate of 4.5 mL/s. The image quality and effective radiation dose (ED) were compared.

Results: There were no significant differences in basic information between groups A and B. Other than the left PA, RA, and RV, there were no significant differences in the CT attenuation values of relevant vascular structures between groups A and B. There were no significant differences in CNR values between the two groups except the LAD-D and LCX. The image quality scores were comparable between groups A and B except the CAs. However, there were significant differences between the two groups in ICM (p < 0.05), scanning time (p < 0.001) and ED (p = 0. 023).

Conclusions: The optimized TRO-CTA scanning protocol can achieve less ICM and lower ED while maintaining image quality.

背景:三重排除计算机断层血管造影(TRO-CTA)最近成为一种无创评估冠状动脉(CAs)、肺动脉(PAs)和胸主动脉(TA)的技术。目的:探讨一种优化的扫描方案在TRO-CTA患者中减少碘造影剂(ICM)体积、注射速率和放射剂量的可行性。方法:采用16 cm宽探测器CT将行TRO-CTA的患者分为A组和B组。A组患者采用传统的三重扫描方案,包括PA、ca和TA序列。B组采用改良方案成像,扫描顺序为PA、TA、CAs, ICM为55 ml,注射速率为4.5 ml /s。比较了图像质量和有效辐射剂量(ED)。结果:A、b两组间基本信息无显著差异,除左PA、RA、RV外,两组间相关血管结构的CT衰减值无显著差异。除LAD-D、LCX外,两组间CNR值无显著差异。除ca外,A组和B组的图像质量评分具有可比性。结论:优化后的TRO-CTA扫描方案可以在保持图像质量的同时实现更低的ICM和更低的ED。
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引用次数: 0
Investigating clinical indicators for neuroimaging abnormalities in acute headache cases: insights from a retrospective study. 研究急性头痛病例神经影像学异常的临床指标:来自回顾性研究的见解。
IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-06-01 Epub Date: 2025-05-14 DOI: 10.1007/s10140-025-02347-0
Felipe Mejía-Herrera, Roger Figueroa-Paz, Jaime Quintero-Ramirez, Luis Alfonso Bustamante-Cristancho

Purpose: Headache is common at emergency services and neuroimaging can help in timely diagnosis of life-threatening pathologies. We evaluated clinical indicators associated with abnormal neuroimaging in patients with acute headache, aiming to develop a scoring system with reliable diagnostic performance.

Methods: This analytical and retrospective study was conducted at a teaching tertiary care hospital in Cali, Colombia, from January 2011 to December 2019. Patients aged 18 years or older with non-traumatic headaches who attended the emergency department and underwent neuroimaging were included. Demographic and clinical data were recorded, including headache associated signs and symptoms, imaging diagnosis and disposition. Statistically significant variables and clinically relevant variables were selected. Data was analyzed using a combination of logistic regression and Receiver Operator Characteristic (ROC) curves, leading to the derivation of three models.

Results: 626 patients were included, 15.5% with abnormal neuroimaging. The variables with the highest odds ratio (OR) were: age > 40 years (OR 3.2 CI 1.86-5.56), motor deficit (OR 5.4 CI 2.62-11.18), visual deficit (OR 3.2 CI 1.56-6.63) and gait disturbance (OR 2.27 CI 0.87-5.96). Three abnormal neuroimaging prediction logistic regression models have been derived. The better scale is performed with model 1, which is validated internally and a cut-off point of 0.179, the Area Under the Curve (AUC) of 0.757 is obtained with a diagnostic accuracy of 0.79 (0.73-0.85).

Conclusion: Our straightforward scale incorporates clinical factors associated with abnormal neuroimaging, with the aim of improving diagnostic performance and predictive capacity to distinguish patients who require neuroimaging.

目的:头痛是常见的急诊服务和神经影像学可以帮助及时诊断危及生命的病理。我们评估了与急性头痛患者异常神经影像学相关的临床指标,旨在建立一个具有可靠诊断性能的评分系统。方法:本研究于2011年1月至2019年12月在哥伦比亚卡利的一家三级教学医院进行分析和回顾性研究。年龄在18岁或以上的非创伤性头痛患者就诊于急诊科并接受了神经影像学检查。记录了人口统计学和临床数据,包括头痛相关的体征和症状、影像学诊断和处置。选取具有统计学意义的变量和临床相关的变量。数据分析采用逻辑回归和接收算子特征(ROC)曲线相结合,导致三个模型的推导。结果:纳入626例患者,神经影像学异常占15.5%。比值比(OR)最高的变量为:年龄0 ~ 40岁(OR 3.2 CI 1.86 ~ 5.56)、运动缺陷(OR 5.4 CI 2.62 ~ 11.18)、视力缺陷(OR 3.2 CI 1.56 ~ 6.63)和步态障碍(OR 2.27 CI 0.87 ~ 5.96)。推导了三种异常神经影像学预测逻辑回归模型。模型1进行了内部验证,截断点为0.179,得到的曲线下面积(AUC)为0.757,诊断精度为0.79(0.73-0.85)。结论:我们的简易量表纳入了与神经影像学异常相关的临床因素,旨在提高诊断性能和预测能力,以区分需要神经影像学检查的患者。
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引用次数: 0
Imaging of acute small bowel pathologies in oncology patients in the ER part I: the role of Computed Tomography (CT) for the evaluation of Tumor and infections. 肿瘤学患者急性小肠病变的影像学研究:第一部分:计算机断层扫描(CT)在肿瘤和感染评估中的作用。
IF 1.7 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Pub Date : 2025-06-01 Epub Date: 2025-04-14 DOI: 10.1007/s10140-025-02341-6
Hajra Arshad, Satomi Kawamoto, Linda C Chu, Elliot K Fishman

Acute abdominal complaints constitute up to 40% of all emergency department (ED) presentations in oncology patients due to a multitude of causes. Small bowel pathologies present a diagnostic challenge due to their diverse range and frequently overlapping clinical presentation. In oncology patients, structural changes resulting from tumor growth, surgery and treatment effects can further complicate the diagnostic process. Due to a weakened immune system, oncology patients are also highly susceptible to infections of the gastrointestinal tract (GIT). Traditional computed tomography (CT) scans are used as the gold standard diagnostic modality. However, three-dimensional (3D) postprocessing techniques including maximal intensity projection (MIP), volume rendering (VR) and cinematic rendering (CR) have been employed to aid image evaluation. For a balanced and organized approach to describe diagnostic challenges in this complex population, we have divided the pictorial essay into two parts. The first part focuses on tumor- and infection-associated causes, as summarized below in the visual abstract. The second part will address treatment-related complications, including chemotherapy, radiotherapy, immunotherapy, graft-versus-host disease and post-surgical complications.

由于多种原因,急腹症主诉占肿瘤患者急诊科(ED)的40%。小肠病理呈现一个诊断挑战,由于其多样化的范围和经常重叠的临床表现。在肿瘤患者中,由于肿瘤生长、手术和治疗效果引起的结构改变会使诊断过程进一步复杂化。由于免疫系统较弱,肿瘤患者也极易受到胃肠道感染(GIT)。传统的计算机断层扫描(CT)被用作金标准诊断方式。然而,三维(3D)后处理技术,包括最大强度投影(MIP),体绘制(VR)和电影渲染(CR)已被用于辅助图像评估。为了平衡和有组织的方法来描述这一复杂人群的诊断挑战,我们将图画文章分为两部分。第一部分的重点是肿瘤和感染相关的原因,总结如下的视觉摘要。第二部分将讨论治疗相关的并发症,包括化疗、放疗、免疫治疗、移植物抗宿主病和术后并发症。
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引用次数: 0
期刊
Emergency Radiology
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