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A Screening Pilot Study on the Relation between Body Mass Index, and Heavy Metal and Mineral Levels in College Students 大学生体质指数与重金属、矿物质含量关系的筛选初步研究
Pub Date : 2019-01-01 DOI: 10.36648/1860-3122.15.3.79
A. Hamouda, Ashraf A. M. Hassan, I. Khardali, Ibraheem M. Attafi, M. Oraiby, M. Attafi, M. Mahmoud, S. F. Salem, Khaled Ali Yahya Sahli, F. Hamdi, Hassan Abdu Ahmed Dohali
Obesity is a chronic metabolic disease identified by excessive fat deposition in the body with the highest risk of disordered lipid profile. Obesity and inappropriate lifestyles such as smoking and fake food not only influence blood lipids but also helps heavy metals and mineral be absorbed and adhered to the tissues with minimal disposal, that producing health problems with ages. A total of 49 female students (18-35 years old) included in this study to assess the relationship between body mass index, heavy metal, and minerals in university students. There is a strong correlation between BMI and potassium, where there is a positively weak relation between selected heavy metal and minerals and BMI. The increases in the presence of heavy metal and minerals in the present study not only depended in the BMI but also as a result of the rise in the effluent flow heavy metal from industrial units found in close nearness to rivers, oceans and seas have ended in an expansion in water bodies and seafood, fruits, vegetable crops and the food chain. That will need further investigation.
肥胖是一种慢性代谢性疾病,其特征是体内脂肪沉积过多,脂质紊乱的风险最高。肥胖和不适当的生活方式,如吸烟和假食品,不仅影响血脂,而且有助于重金属和矿物质被吸收,并以最少的处理粘附在组织中,从而产生年龄的健康问题。本研究以49名18-35岁的女大学生为研究对象,评估大学生身体质量指数与重金属、矿物质的关系。身体质量指数和钾之间有很强的相关性,而某些重金属和矿物质与身体质量指数之间有微弱的正相关。在目前的研究中,重金属和矿物质的增加不仅取决于BMI,而且还取决于废水流量的增加,这些废水来自靠近河流、海洋和海洋的工业单位,最终导致水体、海鲜、水果、蔬菜作物和食物链中的重金属增加。这需要进一步调查。
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引用次数: 4
Levels of Zinc, Magnesium and Iron in Children with Attention Deficit Hyperactivity Disorder 注意缺陷多动障碍儿童锌、镁和铁的水平
Pub Date : 2019-01-01 DOI: 10.36648/1860-3122.13.2.183
A. Division, Jeddah
Background: Attention deficit hyperactivity disorder is a common multifactorial and complex neuro developmental disorder often persisting through adolescence and adulthood. Indications of nutritional treatments with omega-3 fatty acids, and minerals like zinc, magnesium, iron, etc. are gaining importance. We therefore sought to estimate ,and compare the mineral content of zinc, magnesium, and iron in the plasma of ADHD diagnosed children with normal non-ADHD children, and establish a correlation if any with the disorder symptoms. Methods and findings: Psychiatric evaluation was performed using the Diagnostic and Statistical Manual IV and plasma elemental analysis using atomic absorption spectrophotometry. Low levels of zinc, magnesium and iron were observed in ADHD children when compared to their healthy controls. Conclusion: Children with ADHD exhibit lower concentrations of plasma zinc, magnesium, and iron as compared to normal controls which could be correlated with the disorder symptoms in ADHD.
背景:注意缺陷多动障碍是一种常见的多因素和复杂的神经发育障碍,通常持续到青春期和成年期。用omega-3脂肪酸和锌、镁、铁等矿物质进行营养治疗的适应症越来越重要。因此,我们试图估计并比较ADHD诊断儿童与正常非ADHD儿童血浆中锌、镁和铁的矿物质含量,并建立与疾病症状的相关性。方法和发现:使用诊断与统计手册IV进行精神病学评估,使用原子吸收分光光度法进行血浆元素分析。与健康对照组相比,ADHD儿童的锌、镁和铁含量较低。结论:与正常对照相比,ADHD患儿血浆锌、镁和铁的浓度较低,这可能与ADHD的紊乱症状有关。
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引用次数: 1
What? Where? and Who? 怎么啦?在哪里?和谁?
Pub Date : 2018-01-01 DOI: 10.2307/j.ctt22nm7xn.5
Hamada Yz
ISSN 1860-3122 47 Metal Ions Role in Biological Systems The editor-in-chief of this special issue of the Electronic Journal of Biology (EJBio.) under the special issue of building bridges between inorganic chemistry and biology in celebration of prof. Hoffmann’s 80th birthday extended his invitation to many biologically and chemically related scientists over the last couple of months. The aim is to attract biologically sound scientists with a tint of chemistry to submit their work. Areas of interest for this special issue are: Biology, Bioanalytical Chemistry, Bioinorganic Chemistry, Bioorganic Chemistry, Biostatistics, Toxicology and Bio-physical Chemistry [1-5].
金属离子在生物系统中的作用为庆祝Hoffmann教授80岁生日,这期《生物电子杂志》(EJBio.)的特刊《在无机化学和生物学之间建立桥梁》的主编在过去的几个月里向许多生物和化学相关的科学家发出了邀请。其目的是吸引生物学上健全的、有一点化学色彩的科学家提交他们的工作。本期特刊的兴趣领域包括:生物学、生物分析化学、生物无机化学、生物有机化学、生物统计学、毒理学和生物物理化学[1-5]。
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引用次数: 0
Single Nucleotide Polymorphism of Interleukin-27 Gene: A RiskFactor of Recurrent Pregnancy Loss in Iraqi Women 白细胞介素-27基因的单核苷酸多态性:伊拉克妇女复发性流产的危险因素
Pub Date : 2017-01-01 DOI: 10.4103/MJ.MJ_12_18
Esraa H. Humadi, Layla H Hamad, Hasan F Al Azzawie, S. Hamad
Background: Studies have investigated the association between a single nucleotide polymorphism (SNP) of interleukins and the recurrent pregnancy loss (RPL). However, different results have been found in different spots of the world. Studies on the association between the IL-27(-964 A>G) polymorphism and RPL are scarce. This is the first study shows the implication of IL-27(-964 A>G) polymorphism in RPL. Objective: This study aims to investigate the association between RPL and interleukin-27(-964 A>G) polymorphism in Iraqi women. Materials and methods: From September 2013 to September 2014, 100 women, as a control group, and 100 women (with three or more consecutive pregnancy loss), as a study group were chosen to investigate the association between the IL-27(-964 A>G) SNP and the RPL. The IL-27(-964 A>G) SNP was determined using polymerase chain reactionrestriction fragment length polymorphism (PCRRFLP) technique. Genotype and allele frequencies in study group were compared with those in the control group using Fisher tests. Results are considered to be statistically significant if p-value is less than 0.05. Results: The age and the body mass index were not significantly different between the two groups. The frequencies of genotypes of IL-27 polymorphism in the RPL group were AG (60%), AA (31%) and GG (9%); while in control group were AG (21%), AA (68%) and GG (11%). The genotype frequencies of the -964 A>G SNP was significantly different between the study and the control group (p=0.007). Allele frequencies of this polymorphism were A (35%) and G (65%) in RPL group versus A (61%) and G (39%) in the control group. The frequencies of A and G alleles were not significantly different between the two groups. Conclusion: Our findings show that IL-27 (-964 A>G) polymorphism is considered a risk factor of RPL in Iraqi women which was different from what has been found previously; this might implicate other factors in the RPL.
背景:研究已经调查了白介素单核苷酸多态性(SNP)与复发性妊娠丢失(RPL)之间的关系。然而,在世界不同地区发现了不同的结果。关于IL-27(-964 A>G)多态性与RPL之间关系的研究很少。这是首次有研究表明IL-27(-964 A>G)多态性在RPL中的意义。目的:探讨伊拉克妇女RPL与白细胞介素-27(-964 A>G)多态性的关系。材料与方法:2013年9月至2014年9月,选取100名女性作为对照组,100名连续3次及以上流产的女性作为研究组,研究IL-27(-964 a >G) SNP与RPL的关系。采用聚合酶链反应限制性片段长度多态性(PCRRFLP)技术检测IL-27(-964 A>G) SNP。采用Fisher检验法比较研究组与对照组的基因型和等位基因频率。如果p值小于0.05,则认为结果具有统计学意义。结果:两组患者年龄、体质指数差异无统计学意义。RPL组IL-27多态性基因型频率分别为AG(60%)、AA(31%)和GG (9%);对照组为AG(21%)、AA(68%)和GG(11%)。研究组与对照组- 964a >g SNP基因型频率差异有统计学意义(p=0.007)。RPL组的等位基因频率为A(35%)和G(65%),对照组为A(61%)和G(39%)。A和G等位基因的频率在两组间无显著差异。结论:我们的研究结果表明,IL-27 (-964 A>G)多态性被认为是伊拉克妇女RPL的危险因素,这与以往的发现不同;这可能涉及到RPL中的其他因素。
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引用次数: 3
Glucose Transporter Type 1 Deficiency Syndrome (GLUT1) andusing Ketogenic Diet in Treatment of De Vivo Disease: A CaseReports 葡萄糖转运蛋白1型缺乏综合征(GLUT1)和使用生酮饮食治疗体内疾病:一例报告
Pub Date : 2017-01-01 DOI: 10.19080/gjidd.2017.02.555588
E. Lukyanova, L. M. Sushko, S. O. Ayvazyan, K. V. Osipova, Pyr'eva Ea, Sorvacheva Tn, S. S. Zhilina, T. Kozhanova, T. I. Mescheryakova
We present experience of ketogenic Diet (KD) applying in the treatment of pharmaco-resistant epilepsy in patients with Glucose Transporter Deficiency Syndrome Type I (GLUT1). We observed six children with refractory epilepsy due to GLUT1. The high effectiveness of KD in the treatment of GLUT1 was demonstrated. All patients were achieved complete absence of seizures and EEG abnormalities from the beginning of KD. We noticed positive shift in cognitive and speech development for all children. Antiepileptic drugs were stopped taking due to the stable remission. There was a further positive dynamics in intelligence, psychoemotional sphere; the children began to go a nursery school and a special school. Thus, the ketogenic diet is high effectiveness and, perhaps, the only method for GLUT1 treatment. For 100% of children with Glucose Transporter Deficiency Syndrome Type I (GLUT1) using KD to treating and prevention of all types of seizures. The improvement of the quality of life for them we estimated by Hague scale. Using the KD we have achieved the reliable positive changes in the psychomotor development of patients tested by Griffits 2, Griffits 3 scales.
我们介绍了生酮饮食(KD)在治疗葡萄糖转运蛋白缺乏综合征I型(GLUT1)患者的耐药性癫痫中的应用经验。我们观察了6例由GLUT1引起的难治性癫痫患儿。KD对GLUT1的高效治疗已被证实。所有患者从KD开始就完全没有癫痫发作和脑电图异常。我们注意到所有孩子的认知和语言发展都发生了积极的变化。由于病情稳定缓解,停止服用抗癫痫药物。在智力和心理情感领域有进一步的积极动力;孩子们开始上幼儿园和特殊学校。因此,生酮饮食是高效的,也许是治疗GLUT1的唯一方法。对于100%的儿童葡萄糖转运蛋白缺乏综合征I型(GLUT1)使用KD治疗和预防所有类型的癫痫发作。生活质量的提高我们用海牙标准来衡量。使用KD,我们已经在Griffits 2, Griffits 3量表测试的患者的精神运动发展中取得了可靠的积极变化。
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引用次数: 1
Physiological and Morphological Response of Lemon Balm (Melissa officinalis L.) to Prime Application of Salicylic Hydroxamic Acid 柠檬香蜂对水杨酸的生理和形态反应
Pub Date : 2014-01-01 DOI: 10.12692/ijb/5.12.406-412
H. Ardalani, D. E. Asli, P. Moradi
Lemon balm (Melissa officinalis L.), member of Lamiaceae family, is one of the important medicinal plant species. In this study we were investigated the effects of Salicylic hydroxamic acid(SHAM) on seed germination and yield of lemon balm. It was conducted at Agriculture Research Center of Hamedan Province in 2013. SHAM used in 4 different concentrations (0, 50, 75, 100 ppm). Seeds were primed for 8 hours in each concentration, and planted in petri dish. Then, we were assessment some parameter such as seed germination, germination speed, root length, root weight, shoot length, shoot weight, seedling dry weight, enzyme activity, catalase, and peroxidase. This study indicated that SHAM had significant effects on all germination traits and biochemical parameters. Comparison of mean effects of SHAM revealed that the highest germination percent (89%), germination speed (5.41), shoot length (21.15 mm), root length (17 mm), fresh weight (38 mg) and dry weight (8.12 mg). The highest catalase enzymes (23 micromole/mg) and highest peroxidase action (25.66 micromole/mg) were observed at the control concentration. It can be concluded that the SHAM has antioxidant properties and regulate resporiratory system.
香蜂草(Melissa officinalis L.)是一种重要的药用植物,属Lamiaceae科。研究了水杨酸羟肟酸(SHAM)对香蜂草种子萌发及产量的影响。该研究于2013年在哈马丹省农业研究中心进行。SHAM以4种不同浓度(0、50、75、100 ppm)使用。每种浓度的种子培养8小时,然后在培养皿中种植。然后对种子发芽率、萌发速度、根长、根重、茎长、茎重、幼苗干重、酶活性、过氧化氢酶和过氧化物酶进行了评价。本研究表明,SHAM对所有发芽性状和生化指标均有显著影响。SHAM处理的平均效果比较表明,其发芽率(89%)、发芽速度(5.41%)、茎长(21.15 mm)、根长(17 mm)、鲜重(38 mg)和干重(8.12 mg)最高。在对照浓度下,过氧化氢酶活性最高(23微摩尔/mg),过氧化物酶活性最高(25.66微摩尔/mg)。由此可见,SHAM具有抗氧化和调节呼吸系统的作用。
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引用次数: 3
期刊
Electronic Journal of Biology
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