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Epilepsy Currents最新文献

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Environmental Pollutants and Epilepsy: Is It Nrf or Nothing? 环境污染物与癫痫:是 Nrf 还是什么?
IF 5.8 2区 医学 Q1 CLINICAL NEUROLOGY Pub Date : 2024-11-12 DOI: 10.1177/15357597241293295
Ashwini Sri Hari, Cameron S Metcalf
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引用次数: 0
Valproate-is withdrawal worth it? 丙戊酸钠--值得戒断吗?
IF 5.8 2区 医学 Q1 CLINICAL NEUROLOGY Pub Date : 2024-11-05 DOI: 10.1177/15357597241289668
Danielle A Becker
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引用次数: 0
Predicting Pediatric Genetic Epilepsy Through Electronic Medical Records: A Data-Driven Biomarker Discovery Approach. 通过电子病历预测小儿遗传性癫痫:数据驱动的生物标记物发现方法
IF 5.8 2区 医学 Q1 CLINICAL NEUROLOGY Pub Date : 2024-11-04 DOI: 10.1177/15357597241290322
Yi Li
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引用次数: 0
BOLDly Going Where Few Researchers Have Gone Before-Leveraging Language-Related Hippocampal Activations to Predict Postoperative Memory Decline. BOLDly 前无古人--利用与语言相关的海马激活来预测术后记忆衰退。
IF 5.8 2区 医学 Q1 CLINICAL NEUROLOGY Pub Date : 2024-11-03 DOI: 10.1177/15357597241292183
Carrie R McDonald
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引用次数: 0
Chasing the Holy Grail: Seizure Prediction Through Neural Cycles. 追逐圣杯:通过神经循环预测癫痫发作。
IF 5.8 2区 医学 Q1 CLINICAL NEUROLOGY Pub Date : 2024-10-30 DOI: 10.1177/15357597241281842
Dario J Englot
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引用次数: 0
Salty Battle to Sudden Death: Young vs. Old, Brain vs. Heart. 咸战猝死:年轻与年老,大脑与心脏。
IF 5.8 2区 医学 Q1 CLINICAL NEUROLOGY Pub Date : 2024-10-29 eCollection Date: 2024-11-01 DOI: 10.1177/15357597241289672
Shruthi H Iyer, Kristina A Simeone
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引用次数: 0
Underutilization of Neurodiagnostic Resources in Drug-Resistant Epilepsy. 耐药性癫痫的神经诊断资源利用不足。
IF 5.8 2区 医学 Q1 CLINICAL NEUROLOGY Pub Date : 2024-10-29 eCollection Date: 2024-09-01 DOI: 10.1177/15357597241280486
Danielle M Andrade
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引用次数: 0
Preclinical Testing Strategies for Epilepsy Therapy Development. 癫痫治疗开发的临床前测试策略。
IF 5.8 2区 医学 Q1 CLINICAL NEUROLOGY Pub Date : 2024-10-25 DOI: 10.1177/15357597241292197
Victoria A Riley, Steve C Danzer

The development of antiepileptogenic and disease-modifying treatments for epilepsy is a key goal of epilepsy research. Technological and scientific advances over the past two decades have seen the development of numerous therapeutic approaches, many of which show great promise in animal models. To facilitate and de-risk the translation of these promising approaches, however, rigorous preclinical testing is needed. For the present review, we discuss challenges and approaches to conduct preclinical testing of antiepileptogenic and disease-modifying treatments in animal models.

开发抗癫痫和疾病改变治疗方法是癫痫研究的一个重要目标。过去二十年来,随着技术和科学的进步,人们开发出了许多治疗方法,其中许多在动物模型中显示出了巨大的前景。然而,为了促进这些有前景的方法的转化并降低其风险,需要进行严格的临床前测试。在本综述中,我们将讨论在动物模型中进行抗癫痫和疾病改变治疗的临床前测试所面临的挑战和方法。
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引用次数: 0
Have We Solved the Chicken-and-Egg Conundrum? Hippocampal Sclerosis and Temporal Lobe Epilepsy Following Febrile Status Epilepticus: Results of the 10-Year Follow-up FEBSTAT Study. 我们解决了鸡和蛋的难题吗?热性癫痫状态后的海马硬化和颞叶癫痫:FEBSTAT十年随访研究的结果。
IF 5.8 2区 医学 Q1 CLINICAL NEUROLOGY Pub Date : 2024-10-24 eCollection Date: 2024-11-01 DOI: 10.1177/15357597241279746
Anteneh M Feyissa
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引用次数: 0
Emotional Blind Spots in Juvenile Myoclonic Epilepsy. 青少年肌阵挛性癫痫的情感盲点。
IF 5.8 2区 医学 Q1 CLINICAL NEUROLOGY Pub Date : 2024-10-24 eCollection Date: 2024-11-01 DOI: 10.1177/15357597241280481
Krzysztof Bujarski
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引用次数: 0
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