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Anemia Profile in Pediatric Patients at Pediatric Intensive Care Unit (PICU) of Dr. Soetomo General Academic Hospital Soetomo博士综合学术医院儿科重症监护病房(PICU)儿科患者贫血概况
Pub Date : 2022-07-28 DOI: 10.20473/ijar.v4i22022.80-86
S. Larasati, A. Setyaningtyas, Elizeus Hanindito, Mia Ratwita Andarsini
Introduction: Anemia often occurs in critically ill children and is associated with increased morbidity and mortality in women and children and impaired cognitive and behavioral development in children. Objective: This study aims to understand the profile and characteristics of anemia patients in the critical care population. Materials and Methods: This is a retrospective, descriptive study of the patient's medical records. Data were collected by the total sampling technique. Results: Among 203 patients, 52% were anemic at admission to the Pediatric Intensive Care Unit (PICU), while 45% were anemic at discharge. Anemia tends to be more common in older age and male individuals with their chief complaints being respiratory symptoms, higher mean Red Cell Distribution Width (RDW) levels, and poorer nutritional status. There were 84 patients (41%) who received Packed Red-Cells (PRC) transfusions, among them there were 54 patients (51%) who were anemic at PICU admission. Of the 84 patients who received PRC transfusions during their PICU stay and 43 patients (47%) were anemic on PICU discharge. Conclusion: Anemia is quite common in critically ill children and is dominated by male patients aged under 5 years. Anemia also mostly happens in patients with higher organ dysfunction scores and poorer nutritional status than nonanemic patients. Half of the patients with anemia at the PICU also received PRC blood transfusion.
贫血常发生在危重儿童中,并与妇女和儿童发病率和死亡率增加以及儿童认知和行为发育受损有关。目的:了解重症监护人群中贫血患者的概况和特点。材料和方法:这是一项回顾性的、描述性的患者医疗记录研究。数据采用全抽样法采集。结果:203例患者中,52%在儿童重症监护病房(PICU)入院时贫血,45%在出院时贫血。贫血在老年人和男性个体中更为常见,其主要主诉是呼吸道症状,平均红细胞分布宽度(RDW)水平较高,营养状况较差。84例(41%)患者接受了红细胞(PRC)输血,其中54例(51%)患者在PICU入院时贫血。在PICU住院期间接受PRC输血的84例患者中,有43例(47%)患者在PICU出院时贫血。结论:贫血在危重儿童中较为常见,且以5岁以下男性患者为主。与非贫血患者相比,器官功能障碍评分较高、营养状况较差的患者也多发生贫血。PICU的一半贫血患者也接受了PRC输血。
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引用次数: 0
Low-Dose Ketamine as Perioperative Analgesia in Caesarean Sections in Remote Areas with Limited Medical Supplies 低剂量氯胺酮在医疗物资有限的偏远地区剖宫产术围术期镇痛的应用
Pub Date : 2022-07-28 DOI: 10.20473/ijar.v4i22022.87-97
Y. Avidar, Agustina Salinding, Hamzah, Akhyar Nur Uhud, Maulydia
Introduction: Cesarean section is the most common surgical procedure performed in the world and its postoperative pain is still a major issue in several countries. In a low-resource setting, this management poses a challenge for anesthesiologists. Ketamine is the most used anesthetic drug in the world due to its easy access and proven benefits. Objective: This research aims to analyze the effectiveness of low-dose ketamine as postoperative analgesia in cesarean sections conducted in areas with limited medical supplies. Materials and Methods: A Randomized Controlled Trial (RCT) was done from August 2020 to January 2021 with consenting pregnant patients who had undergone cesarean section. The sampled population was randomized to receive either ketamine intravenously or a placebo before the Subarachnoid Block (SAB). Low dose ketamine was divided into three groups 0.15 mg/kg, 0.25 mg/kg, and 0.5 mg/kg. The outcome was divided into primary outcome (pain score after 1-hour post-operation, 2 hours post-operation, 24 hours post-operation, and 48 hours post-operation) and secondary outcome (Apgar Score in the first minute and 5 minutes, hypotension after SAB, sedative effect during operation, postoperative nausea vomiting, time to receive opioid postoperative as rescue analgesia and total opioid uses). Results and Discussion: This study screened 105 patients and recruited 90 patients that were randomized into two groups consisting of 45 patients that received either low-dose ketamine or a placebo. The groups administered ketamine showed a lower pain score in 1 hour (p-value = 0.0037) and 2 hours post-operation (p-value = 0.0037). They also showed that it could prolong the administration of fentanyl (p-value = 0.0003) and lower total fentanyl used (p-value = 0.0008). The groups administered ketamine showed that there was a sedation effect (p-value = 0.0001) that depended on the dosage used. Conclusion: Intravenous ketamine with low doses can reduce pain scores at 1 hour to 2 hours post-operation and shows the need to reduce opioid requirements.
剖宫产是世界上最常见的外科手术,其术后疼痛在一些国家仍然是一个主要问题。在资源匮乏的环境下,这种管理对麻醉师提出了挑战。氯胺酮是世界上使用最多的麻醉药物,因为它容易获得和证明的好处。目的:分析低剂量氯胺酮在医疗物资紧缺地区剖宫产术中术后镇痛的效果。材料与方法:一项随机对照试验(RCT)于2020年8月至2021年1月在同意剖宫产的孕妇中进行。在蛛网膜下腔阻滞(SAB)之前,抽样人群随机接受氯胺酮静脉注射或安慰剂。低剂量氯胺酮分为0.15 mg/kg、0.25 mg/kg和0.5 mg/kg三组。结果分为主要结果(术后1小时、2小时、24小时、48小时疼痛评分)和次要结果(术后1分钟和5分钟Apgar评分、SAB后低血压、术中镇静效果、术后恶心呕吐、术后接受阿片类药物作为抢救镇痛的时间和阿片类药物总用量)。结果和讨论:本研究筛选了105名患者,并招募了90名患者,随机分为两组,每组45名患者接受低剂量氯胺酮或安慰剂治疗。氯胺酮组术后1 h (p值= 0.0037)和2 h (p值= 0.0037)疼痛评分较低。他们还表明,它可以延长芬太尼的给药时间(p值= 0.0003),并降低芬太尼的总使用量(p值= 0.0008)。给予氯胺酮的组显示有镇静作用(p值= 0.0001),这取决于使用的剂量。结论:小剂量氯胺酮静脉注射可降低术后1 ~ 2小时疼痛评分,显示需要减少阿片类药物的需求。
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引用次数: 0
Early Tracheostomy in Prolonged Mechanical Ventilation Due to Severe Head Injury to Prevent Ventilator-Associated Pneumonia (VAP) 重型颅脑损伤延长机械通气早期气管切开术预防呼吸机相关性肺炎(VAP)
Pub Date : 2022-07-28 DOI: 10.20473/ijar.v4i22022.115-119
P. Ananda, Sony
Introduction: Early tracheostomy needs to be considered if the use of a ventilator is expected to be used for a long time. Early Tracheostomy is recommended because it can improve respiratory function, reduce the risk of Ventilator-Associated Pneumonia, improve patient comfort, cleanse secretions in the throat, reduce laryngeal ulceration, improve mobilization, and speech efforts, and allow treatment outside the Intensive Care Unit (ICU). Case Report: We report four cases of severe head injury with early tracheostomy which illustrates prevent of VAP. In these four cases, early tracheostomy was performed (£ 4 days) with consideration of the initial critical GCS, the location of the lesion, and mechanical ventilation is expected to be used for a long period time. During treatment, there is no VAP which is evidenced by a sputum culture examination. Based on a meta-analysis study early tracheostomy can reduce mortality due to VAP by up to 50% and reduce the length of stay in ICU compared to delayed/late tracheostomy (> 10 days) or prolonged intubation (> 14 days). Conclusion: VAP prevention efforts are carried out by applying VAP Bundle. An early tracheostomy provides more benefits than prolonged intubation or delayed/late tracheostomy. VAP Bundle is performed on every patient who uses a ventilator, and it can be proven scientifically that the application of VAP Bundle can reduce the incidence of VAP by up to 25%.
导读:如果预期长期使用呼吸机,需要考虑早期气管切开术。建议早期气管切开术,因为它可以改善呼吸功能,降低呼吸机相关性肺炎的风险,改善患者舒适度,清洁喉咙分泌物,减少喉部溃疡,改善活动和言语能力,并允许在重症监护病房(ICU)外进行治疗。病例报告:我们报告4例重型颅脑损伤合并早期气管切开术的病例,以说明VAP的预防。在这4例病例中,考虑到初始临界GCS,病变位置,预计长期使用机械通气,早期气管切开(£4天)。在治疗期间,痰培养检查证实无VAP。根据一项荟萃分析研究,与延迟/晚期气管切开术(> 10天)或延长插管(> 14天)相比,早期气管切开术可降低VAP死亡率高达50%,并缩短ICU住院时间。结论:应用VAP Bundle进行VAP预防工作。早期气管切开术比延长插管或延迟/晚期气管切开术提供更多的好处。VAP Bundle对每一位使用呼吸机的患者都进行了VAP Bundle治疗,科学证明VAP Bundle的应用可以将VAP的发生率降低25%。
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引用次数: 0
Anesthetic Management of A Patient with Henoch-Schonlein Purpura for Caesarean Section 一例紫癜剖宫产的麻醉处理
Pub Date : 2022-07-28 DOI: 10.20473/ijar.v4i22022.107-114
I. Wijaya
Introduction: Henoch-Schonlein Purpura or Immunoglobulin-A vasculitis is a systemic vasculitis caused by immune complexes that attack small blood vessels. The classic symptoms of Henoch-Schonlein Purpura include erythema purpura,  arthralgia, gastrointestinal complaints, and renal involvement. Some cases show that pregnancy itself could be the trigger for its recurrence and lead to early delivery. Case report: A 33-year-old patient, G2P1A0 and 35 weeks and 4 days pregnant complained of diarrhea 8 days before hospital admission (8-15 times per day). The patient was diagnosed with Henoch-Schonlein Purpura 3 years ago. Upon monitoring in the ward, the fetus was found to be in a compromised condition and an emergency cesarean section was needed. The patient was assessed as having an ASA II physical status and was anesthetized with regional anesthesia epidural in the sitting position, with a median approach, puncture at L3-L4 level, and with 12 ml of Bupivacaine 0.5% isobaric. Postoperative care was continued in the ward. Discussion: As long as there are no contraindications, a neuraxial block could be performed on parturient patients with Henoch-Schonlein Purpura who would undergo a cesarean section. Neuraxial block, namely epidural block, has the added advantage of being a postoperative analgesic and helps to avoid the use of Non-Steroidal Anti Inflammatory Drugs (NSAIDs) in Henoch-Schonlein Purpura patients who often have renal complications. Conclusion: Caesarean Section with  Henoch-Schonlein Purpura disease has been reported with Epidural Block Anesthesia without complications.
过敏性紫癜或免疫球蛋白a血管炎是一种由免疫复合物攻击小血管引起的全身性血管炎。过敏性紫癜的典型症状包括红斑性紫癜、关节痛、胃肠道不适和肾脏受累。一些病例表明,怀孕本身可能是其复发的触发因素,并导致早产。病例报告:患者33岁,G2P1A0,孕35周4天,入院前8天主诉腹泻(每天8-15次)。患者三年前被诊断为过敏性紫癜。在病房监测后,发现胎儿处于受损状态,需要紧急剖宫产。患者经评估为ASA II级身体状态,采用坐位硬膜外区域麻醉,中位入路,L3-L4位穿刺,12 ml 0.5%等压布比卡因。术后护理继续在病房进行。讨论:只要无禁忌症,可对剖宫产的过敏性紫癜患者行神经轴阻滞。神经轴阻滞,即硬膜外阻滞,具有术后镇痛的额外优势,有助于避免在经常有肾脏并发症的过敏性紫癜患者中使用非甾体抗炎药(NSAIDs)。结论:在硬膜外阻滞麻醉下剖宫产治疗紫癜无并发症。
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引用次数: 0
Anesthesia and Analgesia Management Profile for Airway Surgeries at Dr. Soetomo General Academic Hospital Surabaya 泗水Soetomo博士综合学术医院气道手术的麻醉和镇痛管理概况
Pub Date : 2022-07-28 DOI: 10.20473/ijar.v4i22022.98-106
Agustina Salinding, Widiartha Wahyudi, Arya Pradipta
Introduction: Ear, Nose, and Throat (ENT) surgeries are commonly performed and very often require the surgeon and anesthesiologist to share the same workspace. Over the years, ENT surgery techniques have evolved from conventional methods to computer-assisted intraoperative navigation. In contrast to the past, a minimally invasive approach to paranasal sinus and petrous bone surgery is now preferred. Bleeding, postoperative nausea, and vomiting are complications often encountered in ENT surgery. In addition, pain management during surgery and patient comfort after a surgical procedure is a challenge for anesthesiologists. Therefore, the choice of anesthetic drugs is important. Objective: This study aims to determine the action profile, anesthetic management, and pain management in ENT surgery at Dr. Soetomo General Academic Hospital Surabaya. Materials and Methods: This is a retrospective descriptive study. A total of 177 patients underwent airway surgery. Data were obtained from the Medical Records of the Integrated Surgery Center of Dr. Soetomo General Academic Hospital recorded from January to December 2021. Results and Discussion: Most of the patients were in the age group of 45 - 65 years (40.1%) and a majority were men (65.5%). Most patients who were ≥ 20 years old had a normal nutritional status (54.2%). The most frequent diagnosis was laryngeal cancer (23%), with micro laryngeal surgery being the most frequently performed (35.8%). Most surgeries also needed less than 60 minutes followed by 60 to 119 minutes (27.1%). The most frequently used induction agents were a combination of propofol, fentanyl, and rocuronium (39.5%), with isoflurane as the most frequent inhalation agent (91.3%). Metamizole (70.1%) was the most postoperative analgesic. Conclusion: In general, intravenous agents were used for anesthesia induction. A combination of different induction agents brings synergistic benefits.
耳鼻喉(ENT)手术是一种常见的手术,通常需要外科医生和麻醉师共用一个工作空间。多年来,耳鼻喉外科技术已经从传统方法发展到计算机辅助术中导航。与过去相比,微创入路鼻窦和岩骨手术现在是首选。出血、术后恶心和呕吐是耳鼻喉科手术常见的并发症。此外,手术过程中的疼痛管理和手术后患者的舒适度对麻醉师来说是一个挑战。因此,麻醉药物的选择很重要。目的:本研究旨在确定泗水Soetomo博士综合学术医院耳鼻喉外科的动作概况、麻醉管理和疼痛管理。材料与方法:本研究为回顾性描述性研究。共有177例患者接受了气道手术。数据来自Dr. Soetomo综合学术医院综合外科中心2021年1月至12月记录的医疗记录。结果与讨论:患者年龄以45 ~ 65岁居多(40.1%),男性居多(65.5%)。年龄≥20岁的患者营养状况正常(54.2%)。最常见的诊断是喉癌(23%),最常见的是微喉手术(35.8%)。大多数手术时间小于60分钟,其次为60 ~ 119分钟(27.1%)。最常用的诱导剂是异丙酚、芬太尼和罗库溴铵的组合(39.5%),最常用的吸入剂是异氟醚(91.3%)。甲胺唑(70.1%)是最常用的术后镇痛药。结论:麻醉诱导一般采用静脉用药。不同诱导剂的组合可带来协同效应。
{"title":"Anesthesia and Analgesia Management Profile for Airway Surgeries at Dr. Soetomo General Academic Hospital Surabaya","authors":"Agustina Salinding, Widiartha Wahyudi, Arya Pradipta","doi":"10.20473/ijar.v4i22022.98-106","DOIUrl":"https://doi.org/10.20473/ijar.v4i22022.98-106","url":null,"abstract":"Introduction: Ear, Nose, and Throat (ENT) surgeries are commonly performed and very often require the surgeon and anesthesiologist to share the same workspace. Over the years, ENT surgery techniques have evolved from conventional methods to computer-assisted intraoperative navigation. In contrast to the past, a minimally invasive approach to paranasal sinus and petrous bone surgery is now preferred. Bleeding, postoperative nausea, and vomiting are complications often encountered in ENT surgery. In addition, pain management during surgery and patient comfort after a surgical procedure is a challenge for anesthesiologists. Therefore, the choice of anesthetic drugs is important. Objective: This study aims to determine the action profile, anesthetic management, and pain management in ENT surgery at Dr. Soetomo General Academic Hospital Surabaya. Materials and Methods: This is a retrospective descriptive study. A total of 177 patients underwent airway surgery. Data were obtained from the Medical Records of the Integrated Surgery Center of Dr. Soetomo General Academic Hospital recorded from January to December 2021. Results and Discussion: Most of the patients were in the age group of 45 - 65 years (40.1%) and a majority were men (65.5%). Most patients who were ≥ 20 years old had a normal nutritional status (54.2%). The most frequent diagnosis was laryngeal cancer (23%), with micro laryngeal surgery being the most frequently performed (35.8%). Most surgeries also needed less than 60 minutes followed by 60 to 119 minutes (27.1%). The most frequently used induction agents were a combination of propofol, fentanyl, and rocuronium (39.5%), with isoflurane as the most frequent inhalation agent (91.3%). Metamizole (70.1%) was the most postoperative analgesic. Conclusion: In general, intravenous agents were used for anesthesia induction. A combination of different induction agents brings synergistic benefits.","PeriodicalId":117902,"journal":{"name":"Indonesian Journal of Anesthesiology and Reanimation","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134340860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Airway Foreign Bodies in Patients that Underwent Bronchoscopies with General Anesthesia in Dr. Soetomo General Academic Hospital Surabaya 泗水Soetomo综合学术医院全麻支气管镜检查患者气道异物
Pub Date : 2022-07-28 DOI: 10.20473/ijar.v4i22022.72-79
Annisa Maya Sabrina, Maulydia, R. F. Perdana, Mariza Fitriati
Introduction: Airway foreign body (AFBs) is the most common emergency for ENT-HN (Ear, Nose, Throat-Head Neck) that requires immediate treatment. The gold standard management for AFBs is a bronchoscopy performed under general anesthesia (GA). Objective: This study aims to determine the profile of AFBs patients who underwent bronchoscopies with GA at Dr. Soetomo General Hospital Surabaya from January 2018 – December 2019. Methods and Materials: This is a descriptive, retrospective study that uses data from medical records. Microsoft Excel was used to analyze the data. 22 patients met the inclusion criteria. Results: The most common ages were 11 to 20-year-olds (73%), 55% were female, and 45% were male. The patients were from outside (73%) and inside (27%) Surabaya. As much as 67% of the sampled patients had coughs and 23% were symptomless. The foreign bodies found were pins (67%), clipboard nails (14%), and nuts (9%). These AFBs were located in the left main bronchus (45%), trachea (32%), and right main bronchus (18%), and in 5% of these cases, the AFBs could not be located. The duration between the event and the bronchoscopy was mostly less than 1 day (54%), 2 days (32%), and 3 days (14%). Most cases (90%) were without AFBs complications, but some had obstruction (5%), and hemoptysis (5%). Most patients also had an uncomplicated bronchoscopy (81%), however, some suffered lesions (14%) and bleeding (5%). A majority of the patients were also ASA I (68%), and the remainder were classified as ASA II (18%), and III (14%). The premedication drugs administered were fentanyl (41%), and a combination of fentanyl and midazolam (41%). Meanwhile, the most frequently maintained anesthetic agent was Isoflurane+O2 (27%). Most patients also did not have any comorbid factors (85%), but some had anemia (5%), obstruction (5%), as well as obesity followed by sputum retention and hypernatremia (5%). Conclusion: Most AFB patients who underwent bronchoscopy under GA were 11-20 years old, female, and had a cough as a clinical symptom. Most AFBs were pins at the left main bronchus. The duration between the incident and the bronchoscopy was less than 1 day. There were also mostly no complications of AFBs and bronchoscopies. The most common physical status in patients was ASA I, with fentanyl only or fentanyl and midazolam as a premedication drug. The most common agent used to maintain the anesthesia was a combination of isoflurane and O2. Most patients also had no comorbid factors for GA.
简介:气道异物(AFBs)是ENT-HN(耳、鼻、喉-头颈)最常见的急症,需要立即治疗。房颤的金标准治疗是在全身麻醉下进行支气管镜检查。目的:本研究旨在确定2018年1月至2019年12月在泗水Soetomo总医院接受GA支气管镜检查的AFBs患者的概况。方法和材料:这是一项描述性、回顾性研究,使用的数据来自医疗记录。使用Microsoft Excel对数据进行分析。22例患者符合纳入标准。结果:11 ~ 20岁最常见(73%),其中女性占55%,男性占45%。患者分别来自泗水市外(73%)和城内(27%)。多达67%的样本患者咳嗽,23%的患者无症状。发现的异物包括大头针(67%)、剪贴板钉(14%)和螺母(9%)。这些房颤位于左主支气管(45%)、气管(32%)和右主支气管(18%),其中5%的病例无法定位房颤。从事件到支气管镜检查的持续时间大多小于1天(54%),2天(32%)和3天(14%)。大多数病例(90%)无AFBs并发症,但部分患者有梗阻(5%)和咯血(5%)。大多数患者也进行了无并发症的支气管镜检查(81%),然而,一些患者出现病变(14%)和出血(5%)。大多数患者也是ASA I(68%),其余分为ASA II(18%)和ASA III(14%)。用药前用药为芬太尼(41%)和芬太尼联合咪达唑仑(41%)。同时,最常维持的麻醉药物是异氟烷+O2(27%)。大多数患者也没有任何合并症(85%),但一些患者有贫血(5%),梗阻(5%),以及肥胖,随后有痰潴留和高钠血症(5%)。结论:GA下行支气管镜检查的AFB患者多为11-20岁,女性,临床症状以咳嗽为主。大多数afb位于左主支气管。从事件到支气管镜检查的时间少于1天。大多数患者也没有房颤和支气管镜检查的并发症。患者最常见的身体状态是ASA I,仅芬太尼或芬太尼和咪达唑仑作为用药前药物。维持麻醉最常用的药物是异氟醚和氧气的组合。大多数患者也没有GA的合并症因素。
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引用次数: 1
Severe Preeclamptic Patients in The Resuscitation Room of Dr. Soetomo General Academic Hospital Surabaya: A Retrospective Study 泗水Soetomo综合学术医院复苏室重症子痫前期患者的回顾性研究
Pub Date : 2022-07-28 DOI: 10.20473/ijar.v4i22022.62-71
Neissya Nastiti Firmanto, Maulydia, Pungky Mulawardhana, Mariza Fitriati
Introduction: Preeclampsia is the leading cause of maternal and fetal death. This is an urgency in maternal health, especially in developing countries such as Indonesia. Patients with severe preeclampsia who had critical conditions tend to be admitted to the resuscitation room for assistance from more skilled personnel and more sophisticated technology. Objective: This study aims to determine the complications, treatments, and outcomes of severe preeclampsia patients managed in the resuscitation room at Dr. Soetomo General Academic Hospital from January 1st, 2018 – December 31th 2019. Methods and Materials: The method used in this study was retrospective descriptive using medical records and analyzed using Microsoft Excel. Eighty-one samples met the inclusion criteria. Results: The majority of patients were aged 20-35 years (65.43%) and had completed senior high school (88.89%). Most patients were having stage 2 obesity (44.44%) and multigravida (41.97%). A history of preeclampsia and hypertension was not found in the majority of patients. Most patients are diagnosed with late-onset preeclampsia (69.14%). The majority of patients were referred from secondary health facilities (96.30%). The most common complication was pulmonary edema(53.09%). The majority of patients had 2 complications (43.17%) with the most common combinations being eclampsia and HELPP syndrome (13.58%). Intubation is given to the majority of patients (70.37%) and most often in patients with eclampsia (56.14%). Termination of pregnancy by cesarean section is carried out in the majority of patients (72.84%). There were no cases of maternal death in this study. Most of the fetal born had prematurity (70.11%), low birth weight (60%), and asphyxia as assessed by the first minute APGAR score (72.97%) and fifth minute APGAR score (54.05%). Conclusion: The majority of preeclampsia patients with complications in the resuscitation room at Dr. Soetomo General Academic Hospital Surabaya from January 1st 2018-December 31rd 2019 had good maternal outcomes but not the fetal outcome.
子痫前期是导致产妇和胎儿死亡的主要原因。这是孕产妇保健的一个紧迫问题,特别是在印度尼西亚等发展中国家。病情危重的严重先兆子痫患者往往会被送进复苏室,接受更熟练的人员和更先进的技术的帮助。目的:本研究旨在了解2018年1月1日至2019年12月31日Dr. Soetomo综合学术医院复苏室重症子痫前期患者的并发症、治疗方法和结局。方法与材料:本研究采用病历回顾性描述法,使用Microsoft Excel进行分析。81个样本符合纳入标准。结果:患者年龄以20 ~ 35岁为主(65.43%),高中学历占88.89%。多数患者为2期肥胖(44.44%)和多胎妊娠(41.97%)。大多数患者没有子痫前期和高血压病史。大多数患者被诊断为迟发性子痫前期(69.14%)。大多数患者是从二级卫生机构转诊的(96.30%)。最常见的并发症是肺水肿(53.09%)。多数患者合并2种并发症(43.17%),其中以子痫合并HELPP综合征最常见(13.58%)。大多数患者(70.37%)给予插管,最常见于子痫患者(56.14%)。大多数患者(72.84%)选择剖宫产终止妊娠。在本研究中没有产妇死亡病例。以第一分钟APGAR评分(72.97%)和第五分钟APGAR评分(54.05%)评价,多数胎儿早产(70.11%)、低出生体重(60%)、窒息。结论:2018年1月1日至2019年12月31日在泗水Soetomo综合学术医院复苏室就诊的伴有并发症的先兆子痫患者,多数产妇结局良好,但胎儿结局不佳。
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引用次数: 1
Effect of Snakehead Fish and Sea Cucumber Extract Administration on Mast Cell Infiltration, Interlukin-6 (IL-6), and Albumin Levels in Burns and Surgical Wounds 黑鱼和海参提取物对烧伤和外科创面肥大细胞浸润、白细胞介素-6 (IL-6)和白蛋白水平的影响
Pub Date : 2022-01-26 DOI: 10.20473/ijar.v4i12022.1-5
Purwoko Purwoko, B. Putro, Arif Zuhal Amin Hananto
Introduction: Burn injury impairs almost every organ system, which causes significant morbidity and mortality. Meanwhile, the phases included in burn healing are inflammation, cell recruitment, matrix deposition, epithelialization, and tissue remodeling phase. Previous studies showed that snakehead fish and sea cucumber extract have these effects and are beneficial in burn and post-surgery wounds. Objective: This study aims to analyze the effect of snakehead fish and sea cucumber extract supplementation towards mast cell infiltration, IL-6, and albumin level in burn and post-surgery wounds. Materials and Methods: A double-blind randomized control trial was carried out at Dr. Moewardi Hospital Surakarta in November 2017 on 30 subjects, which were divided into 2 groups. Mast cell infiltration was observed on burn and post-surgery wounds colored with Toluidine Blue, while IL-6 and albumin were measured -blood, where both groups had comparable basic characteristics. Results and Discussion: There was a statistically insignificant (p=0.835) higher increase in albumin level in the treatment group, while an insignificant (p=0.056) greater decrease also occur in the IL-6 level. The decrease in cell mast infiltration after treatment was also higher and not statistically significant (p=0.526). Previous studies showed that amino acids from snakehead fish play an important role in wound healing. Meanwhile, high EPA content in sea cucumber is due to its ability as an Echinodermata to regenerate tissue. It was also discovered that the results available about sea cucumber and sea snake extract on wound healing are different based on the skin condition after the use of the extracts. Conclusion: Snakehead fish and sea cucumber extract supplementation can increase albumin level, decrease IL-6 level and mast cell infiltration in burn or post-surgery wounds.
引言:烧伤损害几乎每一个器官系统,导致显著的发病率和死亡率。同时,烧伤愈合包括炎症期、细胞募集期、基质沉积期、上皮化期和组织重塑期。先前的研究表明,黑头鱼和海参提取物具有这些作用,对烧伤和术后伤口有益。目的:分析添加黑鱼海参提取物对烧伤及术后创面肥大细胞浸润、IL-6及白蛋白水平的影响。材料与方法:于2017年11月在雅加达Dr. Moewardi医院进行了一项双盲随机对照试验,30名受试者分为2组。烧伤创面和术后创面甲苯胺蓝染色观察肥大细胞浸润,血中检测IL-6和白蛋白,两组基本特征相似。结果与讨论:治疗组白蛋白水平升高,差异有统计学意义(p=0.835); IL-6水平下降,差异有统计学意义(p=0.056)。治疗后细胞肥大浸润减少率也较高,但无统计学意义(p=0.526)。以往的研究表明,黑头鱼的氨基酸在伤口愈合中起着重要作用。同时,海参中EPA的高含量是由于其作为棘皮动物具有再生组织的能力。研究还发现,海参和海蛇提取物对伤口愈合的效果因使用后皮肤状况的不同而不同。结论:添加黑鱼海参提取物可提高烧伤及术后创面白蛋白水平,降低IL-6水平和肥大细胞浸润。
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引用次数: 0
Successful Anesthetic Management from Separation Surgery of Pygopagus Conjoined Twin; Lesson-Learning With A Teleanesthesia Pygopagus连体双胞胎分离手术的成功麻醉处理远程麻醉的经验教训
Pub Date : 2022-01-26 DOI: 10.20473/ijar.v4i12022.37-46
M. Adhi, Arie Utariani, Lucky Andriyanto
Introduction: The management of conjoined twins requires multidisciplinary teamwork. The complex problems in conjoined twin separation surgery are challenging for anesthesiologists without experience in the management of conjoined twins. Objective: To describe anesthetic management and utilization of teleanesthesia in conjoined twin separation surgery. Case Report: Sixty days-old pygopagus type conjoined twins, with a total body weight of 7030 grams. Both babies looked healthy, moved actively, found no respiratory function disorders, were hemodynamically stable and had no congenital abnormalities. The sacral region's computerized tomography scan (CT-scan) reveals conjoined twins with skin unification and subcutaneous in the perianal region and no internal-vertebral-spinal fusion. Two anesthesia teams performed the management of anesthesia. After confirming there was no cross-circulation with the atropine test, we alternately induced anesthesia by inhalation technique while maintaining spontaneous breathing. Anesthesia was maintained with sevoflurane 2.0-3.0 vol%, in a mixture of oxygen and air with a flow of 4 L/min using Jackson Reese. Circulating volume, hemodynamic stability, and normothermia were maintained intraoperatively. The separation surgery lasted 20 minutes, and the total surgical time for each baby was two hours. Awake extubation was performed immediately after the surgery was complete. Both babies underwent postoperative care at the PICU and were discharged on day 11. During the pre-operative for surgery, the local team conducted telemedicine consultations with the pediatric anesthesia team at Dr. Soetomo hospital and performed intra-anesthesia telementoring. Conclusion: Careful preparation and pre-operative evaluation, proper intra-anesthesia maintenance and monitoring, as well as good communication and teamwork, are keys to successful anesthesia management in conjoined twin separation surgery. Consultation and assistance from an experienced team during surgery using teleanesthesia are significantly beneficial to the anesthesiologist without experience in conjoined twin separation surgery.
导言:连体双胞胎的治疗需要多学科的团队合作。连体双胞胎分离手术的复杂问题对没有连体双胞胎管理经验的麻醉师来说是一个挑战。目的:探讨远程麻醉在连体双胞胎分离手术中的麻醉管理及应用。病例报告:60日龄侏儒型连体双胞胎,总体重7030克。两个婴儿看起来都很健康,活动活跃,没有发现呼吸功能障碍,血液动力学稳定,没有先天性异常。骶骨区域的计算机断层扫描(ct)显示连体双胞胎有皮肤统一和肛周皮下,没有内-椎-脊柱融合。两个麻醉小组进行麻醉管理。经阿托品试验确认无交叉循环后,在保持自主呼吸的同时交替采用吸入性技术诱导麻醉。麻醉用体积% 2.0 ~ 3.0的七氟醚维持,在氧气和空气的混合物中,使用Jackson Reese,流量为4l /min。术中维持循环容量、血流动力学稳定性和正常体温。分离手术持续20分钟,每个婴儿的总手术时间为2小时。手术完成后立即进行清醒拔管。两名婴儿在PICU接受了术后护理,并于第11天出院。在手术前,当地团队与Dr. Soetomo医院的儿科麻醉团队进行了远程医疗会诊,并进行了麻醉内远程监护。结论:精心的术前准备和评估,正确的麻醉维持和监护,良好的沟通和团队合作是连体双胞胎分离手术麻醉管理成功的关键。对于没有连体双胞胎分离手术经验的麻醉师来说,远程麻醉手术过程中有经验的团队的咨询和协助是非常有益的。
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引用次数: 0
EuroSCORE II as Predictor of Mortality and Morbidity in Post-CABG Patient in Dr. Soetomo General Academic Hospital EuroSCORE II作为Dr. Soetomo综合学术医院cabg术后患者死亡率和发病率的预测因子
Pub Date : 2022-01-26 DOI: 10.20473/ijar.v4i12022.14-21
Rama Azalix Rianda, B. Semedi, Agus Subagjo, Y. Avidar
Introduction: European System for Cardiac Operative Risk Evaluation (EuroSCORE) is a scoring system to predict mortality risk after cardiac surgery. EuroSCORE II was introduced to replace and show superiority over EuroSCORE I which tends to overestimate the risk of heart surgery procedures and have a low discrimination ability. Meanwhile, this is the first study to analyze EuroSCORE II as a predictor of mortality and morbidity in Indonesians. Objective: This study aims to analyze EuroSCORE II as a predictor of mortality and morbidity in Indonesians. Materials and Methods: This is a retrospective study using medical records of CABG patients in Dr. Soetomo General Academic Hospital from January 2016 to December 2017. Results and Discussion: Out of 39 Patients who have performed CABG surgery, most were male (89.7%) with the highest age range of 46-65 years (59%). Deceased patients had an average EuroSCORE II of 22.36% and SD±26.97%7%, while 27 patients who survived had an average EuroSCORE II of 6.78% and SD±6.4%. Based on morbidity assessment, EuroSCORE II only accurately predicted the risk of kidney failure and did not properly assess the length of inotropic use, vasopressors, hospitalization time, the risk of arrhythmias, low cardiac output syndrome, Durante-operative bleeding, and the need for blood transfusion. These inaccuracies occurred because the samples that were included varied based on their standard deviation and pattern-less graph. Conclusion: EuroSCORE II is inadequate to predict morbidity and mortality in postoperative patients, therefore, it is considered less effective.
简介:欧洲心脏手术风险评估系统(EuroSCORE)是一个预测心脏手术后死亡风险的评分系统。引入EuroSCORE II是为了取代EuroSCORE I,并显示其优越性,EuroSCORE I往往高估心脏手术的风险,并且识别能力较低。同时,这是第一个分析EuroSCORE II作为印度尼西亚人死亡率和发病率预测因子的研究。目的:本研究旨在分析EuroSCORE II作为印度尼西亚人死亡率和发病率的预测因子。材料与方法:回顾性研究2016年1月至2017年12月Dr. Soetomo综合学术医院CABG患者的医疗记录。结果与讨论:39例行CABG手术的患者中,大多数为男性(89.7%),年龄最大的为46-65岁(59%)。死亡患者平均EuroSCORE II为22.36%,SD±26.97%7%;存活患者27例,平均EuroSCORE II为6.78%,SD±6.4%。基于发病率评估,EuroSCORE II仅准确预测肾功能衰竭的风险,而没有正确评估肌力药物使用时间、血管加压药物、住院时间、心律失常风险、低心输出量综合征、durante手术出血和输血需求。这些不准确的发生是因为所包含的样本根据其标准偏差和无模式图而变化。结论:EuroSCORE II不足以预测术后患者的发病率和死亡率,因此认为其效果较差。
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引用次数: 1
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Indonesian Journal of Anesthesiology and Reanimation
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