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Intracranial Hemorrhage in Patients With Hemophilia A 血友病A型患者颅内出血的研究
Pub Date : 2020-07-29 DOI: 10.20473/ijar.v2i22020.22-29
N. S. Budi, P. Airlangga, B. Semedi
Introduction: Intracranial hemorrhage in inherited bleeding disorders is a medical emergency. The location of bleeding in most children is subdural and the most common cause is hemophilia. Although intracranial bleeding that occurs in people with hemophilia ranges from less than 5% of events, it is a life-threatening medical emergency so appropriate treatment is needed. Case Report: A boy patient 11 years old, 20kg weights have a seizure at home and followed by a decrease in consciousness. It was founded abnormalities in the form of anemia, prolonged FH (PPT 4x and APTT 4x), and hypocalcemia. The patient then was given main therapy; FVIII 100 IU/dL according to the FVIII target level calculated. The therapy continued with 500IU/12 hours according to the daily target of FVIII 50IU/dL. Discussion: The patient’s condition was getting better day by day. The patient’s consciousness started to improve after 14 days of postoperative. One month after that, the patient received koate treatment as the episodic handler. Diagnosing the exact cause in patients who have intracranial hemorrhage provides appropriate management so that the patients could be helped. Conclusion: Good collaboration between anesthesiologists, neurosurgeons, and pediatrics will increase the probability of successful management of critical bleeding without major sequelae.
简介:遗传性出血性疾病的颅内出血是一种急症。大多数儿童的出血部位在硬膜下,最常见的原因是血友病。虽然血友病患者颅内出血的发生率不到5%,但这是危及生命的医疗紧急情况,因此需要适当的治疗。病例报告:一名11岁,体重20公斤的男孩患者在家中癫痫发作,随后意识下降。发现异常表现为贫血、FH延长(PPT 4x和APTT 4x)和低钙血症。给予主治疗;FVIII按100 IU/dL的FVIII目标水平计算。按照FVIII 50IU/dL的每日目标,继续500IU/12小时的治疗。病人的情况一天比一天好。术后14天后患者意识开始好转。一个月后,患者作为发作性处理者接受koate治疗。诊断颅内出血患者的确切原因可以提供适当的治疗,从而帮助患者。结论:麻醉医师、神经外科医师和儿科医师之间的良好合作将提高重症出血无重大后遗症的成功率。
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引用次数: 0
Myasthenia Crisis Vs Cholinergic Crisis: Challenges in Crisis Management Without Plasmapheresis or Intravenous Immunoglobulin (IVIG) 肌无力危机Vs胆碱能危机:没有血浆置换或静脉注射免疫球蛋白(IVIG)的危机管理的挑战
Pub Date : 2020-07-29 DOI: 10.20473/ijar.v2i22020.16-21
Lila Tri Harjana, Hardiono Hardiono
Introduction: Myasthenia gravis (MG) is an acquired autoimmune disorder clinically characterized by skeletal muscle weakness & fatigability on exertion with prevalence as high as 2–7 in 10,000 and women are affected more frequently than men (~3:2). Over 12-16% of generalized MG patients experience crisis once in their lifetime. A serious complication of myasthenia gravis is respiratory failure. This may be secondary to an exacerbation of myasthenia (myasthenia crisis) or to treatment with excess doses of a cholinesterase inhibitor (cholinergic crisis). Case Report: Thirty-two years old woman refereed from a private hospital to ED for further treatment with myasthenia in crisis, after nine days of treatment in the previous ICU. Patient already in intubation with mechanical ventilation and history of the treatment of a high dose of multiple anticholinesterase drugs and steroids without plasmapheresis or immunoglobulin intravenous. During admission, diarrhea was present, with no sign of GI infection. On the third day of admission, the patient performed a Spontaneous Breathing Trial and was a success then extubated. Then two day after extubation, the patient falls to respiratory failure and need mechanical ventilation. Anticholinesterase test was performed, and it shows no improvement in clinical signs, and diagnose as Cholinergic Crisis. After re-adjustment of anticholinesterase drug with a lower dose, clinically, the respiratory condition improved, and on the 10th day of admission, the patient was succeed extubated. At 12nd days of ICU admission, patient discharge from ICU. Discussion: Myasthenia and Cholinergic Crisis is a severe and life-threatening condition characterized by generalized muscle weakness with a respiratory compromise that requires ventilatory support. Respiratory failure may be present in the cholinergic crisis without cholinergic symptoms (miosis, diarrhea, urinary incontinence, bradycardia, emesis, lacrimation, or salivation). The most important management aspect of Myasthenia patients in crisis is the recognition and treatment of myasthenia vs cholinergic crisis.
简介:重症肌无力(Myasthenia gravity, MG)是一种获得性自身免疫性疾病,临床表现为骨骼肌无力和运动疲劳,发病率高达2-7 / 10000,女性发病频率高于男性(~3:2)。超过12-16%的广泛性MG患者一生中经历过一次危象。重症肌无力的一个严重并发症是呼吸衰竭。这可能是继发于重症肌无力加重(重症肌无力危象)或过量使用胆碱酯酶抑制剂(胆碱能危象)治疗。病例报告:32岁女性患者在重症监护室治疗9天后,因重症肌无力危象从私立医院转至急诊科接受进一步治疗。患者已插管机械通气,有大剂量多种抗胆碱酯酶药物和类固醇治疗史,无血浆置换或免疫球蛋白静脉注射。入院时出现腹泻,无胃肠道感染迹象。入院第三天,患者进行了自主呼吸试验,成功后拔管。拔管2天后,患者出现呼吸衰竭,需要机械通气。行抗胆碱酯酶试验,临床症状无改善,诊断为胆碱能危象。经重新调整低剂量抗胆碱酯酶药物后,临床呼吸情况好转,入院第10天成功拔管。入院第12天,患者出院。讨论:重症肌无力和胆碱能危象是一种严重的危及生命的疾病,其特征是全身性肌肉无力,呼吸系统受损,需要通气支持。胆碱能危象时可出现呼吸衰竭,但无胆碱能症状(贫血、腹泻、尿失禁、心动过缓、呕吐、流泪或流涎)。重症肌无力危象患者最重要的管理方面是对重症肌无力与胆碱能危象的认识和治疗。
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引用次数: 1
Comparing Alteration of MMSE (Mini-Mental State Examination) Scores as Cognitive Function Test in Geriatrics After General and Regional Anesthesia 老年患者全身麻醉和区域麻醉后认知功能测试MMSE评分变化的比较
Pub Date : 2020-07-29 DOI: 10.20473/ijar.v2i22020.10-15
Ferrie Budianto, Philia Setiawan, H. Hamzah, E. Yulianti
Introduction: An alteration of cognitive function in geriatrics often occurred after a surgery procedure. To do a surgery, patients would go through the process with anesthesia, whether it is  general or regional anesthesia. We aimed to identify the effect of general and regional anesthesia in increasing the risk of alteration in cognitive function from geriatrics who underwent elective surgery followed by other risks. Material and Method: This observational analytic study has a total sample of 60 patients who aged 60 years or more, and half of the total sample underwent an elective surgery with general anesthesia, whereas the other half with regional anesthesia at Gedung Bedah Pusat Terpadu Dr. Soetomo General Hospital in a range of October – November 2016. The cognitive function of patients was assessed with MMSE which is done in approximately 10 – 15 minutes. Result and Discussion: There was a statistically significant correlation between age and both preoperative MMSE score also the alteration of MMSE score after 3 days in patients with regional anesthesia (P-value = 0.032; 0.044). Also, the correlation between educational status and preoperative MMSE score (P-value = 0.001). There was also a statistically significant difference in alteration of the MMSE score after 3 days between patients with general and regional anesthesia which went through the hypotension phase (P-value = 0.022; 0.003). We identified that both general and regional anesthesia could lead to alteration of MMSE score (P-value = 0.001; 0.02) and there was a statistically significant difference between both of them (P-value = 0.001). Conclusion: Both general and regional anesthesia could lower the cognitive function of geriatrics, especially general anesthesia which happened to have a higher risk to occur. Other factors such as age, educational status, and hemodynamic condition during surgery, had their impacts toward lowering cognitive function in geriatrics.
在老年医学中,认知功能的改变通常发生在手术后。要做手术,病人要在麻醉的情况下进行,无论是全身麻醉还是局部麻醉。我们的目的是确定全身麻醉和区域麻醉对增加老年患者择期手术后认知功能改变风险的影响。材料和方法:本观察性分析研究共纳入60例60岁及以上的患者,其中一半患者于2016年10月至11月在Gedung Bedah Pusat Terpadu Dr. Soetomo总医院接受了全麻选择性手术,另一半患者接受了区域麻醉。用MMSE评估患者的认知功能,大约10 - 15分钟完成。结果与讨论:年龄与区域麻醉患者术前MMSE评分及3 d后MMSE评分变化均有统计学意义(p值= 0.032;0.044)。此外,教育程度与术前MMSE评分之间存在相关性(p值= 0.001)。经过低血压期的全麻和区域麻醉患者3 d后MMSE评分的改变也有统计学意义(p值= 0.022;0.003)。我们发现全身麻醉和区域麻醉都可能导致MMSE评分的改变(p值= 0.001;0.02),两者差异有统计学意义(p值= 0.001)。结论:全麻和区域麻醉均可降低老年人的认知功能,特别是全麻发生的风险较高。其他因素,如年龄、教育程度和手术时血流动力学状况,对老年人认知功能的降低也有影响。
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引用次数: 4
Ketamine Versus Tramadol Effectiveness as Postoperative Oral Analgesics on Pediatric Patients Age 5-10 Years in Elective Surgery at Dr. Soetomo Hospital Surabaya 氯胺酮与曲马多在泗水Soetomo医生医院择期手术中作为5-10岁儿童患者术后口服镇痛药的效果
Pub Date : 2020-07-29 DOI: 10.20473/ijar.v2i22020.1-9
Herdiani Sulistyo Putri, Elizeus Hanindito, Herdy Sulistyono
Introduction: The use of ketamine and tramadol as postoperative analgesics for pediatric are still relatively rare, especially orally administrated. As an analgesic, ketamine blocks the NMDA receptor, the main excitatory transmitter in CNS; whereas tramadol blocks serotonin and norepinephrine uptake, thus preventing pain transmission on the spinal cord. Objective: The aim of this study is to compare the effectiveness of oral ketamine and oral tramadol as analgesics for postoperative acute pain in children. Method: A double-blind randomized clinical trial was conducted at Dr. Soetomo Hospital. The hospital ethical committee had approved this study. The subject includes thirty children aged 5-10 years old who fulfilled the inclusion criteria. They were divided into either ketamine groups or the tramadol group, in which each group consisting of fifteen patients. The regimen dosage that been given was 2mg/kg tramadol and ketamine as postoperative oral analgesics in the form of simple syrup. The FLACC table was used to evaluate pain score before and after administration of drugs (30-minutes, 1-hour, 2-hours, 3-hours, 4-hours, and at discharge from the recovery room). Result and Discussion: Based on the quantitative parameter of the FLACC (scale 0-10), there was a significant difference (p<0.05) between the first-hour postoperative administration and patient discharge from the recovery room. The patient of ketamine group had far lower FLACC value compared to the tramadol group. Rescue analgesics in the form of intravenous fentanyl were given to one patient (6.7%) in the ketamine group and  four patients (26.7%) in the tramadol group. Conclusion: Ketamine proved to be a better and more effective postoperative oral analgesic compared to tramadol in this study.
氯胺酮和曲马多作为小儿术后镇痛药的使用仍然相对较少,尤其是口服给药。作为一种镇痛药,氯胺酮阻断中枢神经系统主要兴奋性递质NMDA受体;而曲马多阻断血清素和去甲肾上腺素的摄取,从而防止疼痛在脊髓的传递。目的:比较口服氯胺酮和口服曲马多对儿童术后急性疼痛的镇痛效果。方法:在Dr. Soetomo医院进行双盲随机临床试验。医院伦理委员会已经批准了这项研究。受试者为30名符合纳入标准的5-10岁儿童。他们被分为氯胺酮组和曲马多组,每组15名患者。本方案给药剂量为曲马多和氯胺酮以单纯糖浆形式作为术后口服镇痛药2mg/kg。采用FLACC表评估给药前后(30分钟、1小时、2小时、3小时、4小时、出院时)疼痛评分。结果与讨论:基于FLACC的定量参数(0-10分),术后第1小时给药与患者出院间有显著差异(p<0.05)。氯胺酮组患者FLACC值远低于曲马多组。氯胺酮组1例(6.7%)给予芬太尼静脉镇痛,曲马多组4例(26.7%)给予静脉镇痛。结论:与曲马多相比,氯胺酮是一种更好、更有效的术后口服镇痛药。
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引用次数: 0
Triage Knowledge of Emergency Rooms Nurses at Dr Soetomo Regional General Hospital 苏托莫博士地区综合医院急诊室护士的分诊知识
Pub Date : 2020-01-30 DOI: 10.20473/ijar.v2i12020.13-19
Fariza Nur Aini Widyani, April Poerwanto Basuki, Djohar Nuswantoro
Introduction: Triage is a system to sort patients based on their urgency for care during an emergency. In addition, to determine patient’s severity, triage reduces time wasted and overcrowding in the emergency room.1 Triage errors such as over-triage or under-triage must not exceed 35% and 5% of the total numbers of patients respectively. Dr. Soetomo General Hospital of Surabaya with its status as one of type “A” hospital in Indonesia that has good amenities, facilities, and infrastructures which is also the main referral hospital from Primary or Secondary Health Care, is prone to patients overcrowding. The high number of patients and the demands for high-quality service as the main referral hospital require higher qualification from health care professionals in term of cognitive, skills, and attitude. Objective: This study conducted to evaluate the level of knowledge of the ER (Emergency Room) nurses at Dr. Soetomo General Hospital in 2019 towards triage. Methods and Materials: This study is a quantitative descriptive study using a validated questionnaire with 32 nurses as the samples. Results and Discussion: Demographic profile showed that majority of nurses are: female (52%), age 26 – 35 years old (46 %), graduated from D3 (61%), have been working in this field for >15 years (46%), attended Basic Life Support Training (33%), and have moderate knowledge in triage (61%). Conclusion: Emergency room nurses of Dr Soetomo General Hospital had adequate knowledge in triage. The researcher considers there might be some factors influencing nurse’s knowledge in triage.
导言:分诊是在急诊中根据病人急需护理的程度进行分类的系统。此外,分诊还能确定病人的严重程度,减少急诊室的时间浪费和过度拥挤。1 分诊误差(如过度分诊或分诊不足)分别不得超过病人总数的 35% 和 5%。泗水苏托莫医生综合医院是印度尼西亚的一家 "A "级医院,拥有良好的设施、设备和基础设施,同时也是初级或二级医疗保健的主要转诊医院,因此很容易出现病人过度拥挤的情况。作为主要转诊医院,病人数量多,对高质量服务的要求高,这就需要医护人员在认知、技能和态度方面具备更高的资质。研究目的本研究旨在评估 2019 年苏托莫博士综合医院急诊室护士对分诊的认知水平。方法与材料:本研究是一项定量描述性研究,使用经过验证的调查问卷,以 32 名护士为样本。结果与讨论:人口统计学特征显示,大多数护士为女性(52%),年龄在 26 - 35 岁之间(46%),毕业于 D3(61%),在该领域工作超过 15 年(46%),参加过基本生命支持培训(33%),对分诊有一定了解(61%)。结论苏托莫医生综合医院急诊室护士对分诊有足够的了解。研究人员认为,影响护士分诊知识的因素可能有一些。
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引用次数: 0
Social-Fairness Perception in Natural Disaster, Learn from Lombok: A Phenomenological Report 自然灾害中的社会公平感知,从龙目岛学习:一份现象学报告
Pub Date : 2019-07-30 DOI: 10.20473/ijar.v1i12019.1-7
Filipus M Yofrido, Lila Tri Harjana
Introduction: Disasters occur in all areas of the world and cause harm to populations, property, infrastructure, economies, and the environment.1Harm to populations includes death, injury, disease, malnutrition, and psychological stress.1Social-friction often isn’t recognized during disaster response and recovery. Objective: This report explored the existence of social-friction in disaster situation which able to make recovery more complex. Method: This was qualitative study with phenomenology report approach. The data collection was done by indepth interviewing five inhabitants when doing emergency disaster response two weeks after massive earthquake in North Lombok. Result and discussion: Two out of five inhabitants were Lombok native-people, the rest were immigrant. An inhabitant reported their feeling treated unfair by aid agencies because they received less aid than others. In another chance, when distributing clean-water, we were intercepted, they argue that they got more lack of water than another group who live far distally. Both claimed treated unfair making a dispute friction.Ethnic or social origin, language, religion, gender, age, physical or mental disability, and sexual orientation are just some of the deep-rooted causes of social-friction that can have such a devastating impact on their lives.Social-friction in everyday life rarely endangers lives, but in an emergency situation, it can be life-threatening. It affects not only people’s ability to survive the crisis, also their capacity to recover and regain their livelihoods. Conclusion: Risk reduction and preparedness are just as important a part of the process as any aspect of a disaster.Dialogue is fundamental in good programme design, monitoring and evaluation, and systematic efforts to listen to all groups affected by disaster can help pre-empt and remedy unfair-perception.Perhaps,most importantly, understanding and respecting the complex cultural context in which aid agencies are working and using the strategies and mechanismsto detectand minimize social-friction, will result great improvement in the effectiveness and equity of perceived support in humanitarian assistance.2
灾难发生在世界各地,对人口、财产、基础设施、经济和环境造成损害。对人口的危害包括死亡、受伤、疾病、营养不良和心理压力。在灾难应对和恢复过程中,社会摩擦往往没有被意识到。目的:探讨灾害情况下社会摩擦的存在,使灾后恢复变得更加复杂。方法:采用现象学报告法进行定性研究。数据收集是在北龙目岛大地震发生两周后进行紧急救灾时,通过对5名居民进行深度采访完成的。结果和讨论:五分之二的居民是龙目岛本地人,其余是移民。一名居民反映说,他们得到的援助比其他人少,因此感到受到了不公平的对待。还有一次,当我们分发干净的水时,我们被拦截了,他们争辩说,他们比另一个生活在遥远地方的群体更缺水。双方都声称受到了不公平的待遇,造成了纠纷摩擦。种族或社会出身、语言、宗教、性别、年龄、身体或精神残疾以及性取向只是社会摩擦的一些根深蒂固的原因,这些原因可能对他们的生活产生毁灭性的影响。日常生活中的社会摩擦很少危及生命,但在紧急情况下,它可能危及生命。它不仅影响人们度过危机的能力,也影响他们恢复和重获生计的能力。结论:减少风险和做好准备与灾难的任何方面一样,都是这一过程的重要组成部分。对话是良好方案设计、监测和评价的基础,有系统地听取受灾害影响的所有群体的意见有助于预防和纠正不公平的看法。也许,最重要的是,理解和尊重援助机构工作的复杂文化背景,并利用战略和机制来发现和尽量减少社会摩擦,将大大提高人道主义援助的有效性和公平性
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引用次数: 2
Pain Level of Postoperative Orthopedic Patients at Dr. Soetomo General Hospital Soetomo医生总医院骨科术后患者疼痛程度分析
Pub Date : 2019-07-30 DOI: 10.20473/ijar.v1i12019.19-25
David Wicaksono, L. Herawati, Herdy Sulistyono
Introduction: Postoperative pain is the most undesirable consequence of the surgery. If it is not managed properly, it can lead to a long healing. However, assessment and treatment of postoperative pain in surgical wards still have not received attention. Differences in patient’s pain level after surgery and after being transferred to the surgical ward is very important in monitoring the effectiveness postoperative pain management. Objective: This study was conducted to determine the overview of pain level experienced by patients following orthopedic surgery and to know the individual factors that can affect the patient's pain level. Method and Material: This research was observational analytic with 43 orthopedic postoperative patients as a sample. The Patients’ pain level were measured by the Numeric Rating Scale (NRS) at one hour after surgery and 24 hours after surgery. Result and Discussion: The Pain level one hour after surgery varied between pain level 0 as much as 53% to pain level 8 as much as 4.7%. The results of measurements of pain 24 hours after surgery only 23.3% of the patients who did not complain of pain, and there was a patient who experienced pain level 10. The results of the statistical calculation, the difference between the level of pain one hour and 24 hours post-surgery obtained value of p=0.037 (p<0.05). Conclusion: There was a significant difference between the pain level at one hour and 24 hours post-surgery. It might be due to the process of peripheral and central sensitization in patients with delayed pain management. It also may be influenced by individual factors as well as medical personnel.
术后疼痛是手术最不希望发生的后果。如果处理不当,可能会导致很长时间的愈合。然而,外科病房术后疼痛的评估和治疗仍未受到重视。患者手术后和转到外科病房后疼痛程度的差异对监测术后疼痛管理的有效性非常重要。目的:本研究旨在了解骨科术后患者的疼痛水平概况,了解影响患者疼痛水平的个体因素。方法与材料:本研究以43例骨科术后患者为样本进行观察分析。采用数字评定量表(NRS)于术后1小时和24小时测量患者的疼痛程度。结果与讨论:术后1小时疼痛程度在疼痛0级高达53%到疼痛8级高达4.7%之间变化。术后24小时疼痛测量结果仅有23.3%的患者无疼痛主诉,且有1例患者经历了10级疼痛。统计计算结果显示,术后1小时与24小时疼痛程度差异p=0.037 (p<0.05)。结论:术后1 h与24 h疼痛程度有显著性差异。这可能是由于延迟疼痛管理患者的外周和中枢致敏过程。它也可能受到个人因素以及医务人员的影响。
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引用次数: 1
Duration Of Ventilation Support Usage And Development Of Ventilator-Associated Pneumonia: When Is The Most Time At Risk? 呼吸机支持使用的持续时间和呼吸机相关性肺炎的发展:何时是最危险的时间?
Pub Date : 2019-07-30 DOI: 10.20473/ijar.v1i12019.26-31
R. Alfaray, Muhammad Mahfud, Rafiqy Sa’adiy Faizun
Introduction: Ventilator-Associated pneumonia (VAP) is pneumonia that occurs in patients who have been mechanically ventilated for a duration of more than 48 hours. The duration of ventilator use was identified as a risk factor which is a trigger of VAP. Objective: This study aimed to determine the association between the duration of ventilator use and the incidence of VAP in patients in the Intensive Care Unit of Dr. Mohammad Hoesin General Hospital, Palembang. Method and Material: This study was an observational analytic study using a cross-sectional design. The samples were all patients who use a ventilator for more than 48 hours at the ICU room period of July 1, 2014, to June 30, 2015. Data were obtained from the patient’s medical records of a total of 146 patients, but the number of patients who comply with the criteria was 106 patients. Result and Discussion: Out of the 106 samples, 41 patients (38.7%) developed VAP and 65 patients (61.3%) did not develop VAP. The analysis using Chi-Square test showed that patients who used ventilator for >5 days had an OR = 3.273 compared to patients using ventilator 2-5 days (p-value = 0.016; 95% CI = 1.223 to 8.754). Conclusion: There is a significant association between the duration of ventilator use and the incidence of VAP in patients at the ICU of Dr. Mohammad Hoesin General Hospital, Palembang. Patients using ventilators for more than 5 days 3,386 times more at risk of developing VAP compared to patients using ventilators 2-5 days. The riskiest time for the patient using ventilator was more than 5 days of usage. And, the mortality rate of VAP patients was 63.4% from 41 patients while the mortality rate of whole ICU patients was 50.9%.
简介:呼吸机相关性肺炎(VAP)是在机械通气超过48小时的患者中发生的肺炎。使用呼吸机的持续时间被确定为触发VAP的危险因素。目的:本研究旨在确定巨港Dr. Mohammad Hoesin总医院重症监护室患者呼吸机使用时间与VAP发生率之间的关系。方法和材料:本研究为观察性分析研究,采用横断面设计。样本为2014年7月1日至2015年6月30日在ICU病房使用呼吸机超过48小时的患者。从患者病历中获得的数据共146例,但符合标准的患者数量为106例。结果与讨论:106例患者中,41例(38.7%)发生VAP, 65例(61.3%)未发生VAP。卡方检验分析显示,与使用呼吸机2-5天的患者相比,使用呼吸机>5天的患者OR = 3.273 (p值= 0.016;95% CI = 1.223 ~ 8.754)。结论:巨港Dr. Mohammad Hoesin综合医院ICU患者呼吸机使用时间与VAP发生率之间存在显著相关性。使用呼吸机5天以上的患者发生VAP的风险是使用呼吸机2-5天的患者的3386倍。患者使用呼吸机的最危险时间为使用5天以上。41例VAP患者的死亡率为63.4%,而全ICU患者的死亡率为50.9%。
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引用次数: 2
Pain Treatment On Trauma Patient In Dr.Soetomo General Hospital Emergency Room soetomo综合医院急诊室创伤患者疼痛治疗
Pub Date : 2019-07-30 DOI: 10.20473/ijar.v1i12019.13-18
Khoir Amaliin, A. Nurrahmah, Nancy Margarita Rehatta, Choesnan Effendi
Introduction: Uncontrolled pain has many negative effects to the body. The Guideline of Pain Management has been specifically arranged, but assessment and pain treatment in the Emergency Room (ER) have not adequate yet. Integrated pain assessment before and after treatment is very important in monitoring pain management effectiveness. Objective: The aim of this study was to determine pain score of emergency patients before and after treatment. This study was also conducted to record the treatment timing that was given by the paramedics in the emergency room. Method and Material: This study was a description research with 40 trauma patients as samples in the ER at Dr. Soetomo Hospital. Patient’s pain level was measured twice, before the treatment and an hour after that. The pain level was measured using Visual Analog Scale (VAS). Patients were given ketorolac 30mg intravenous as the treatment. Result and Discussion: There were2.5% of the patients VAS 1 and the other 12.5% VAS 10. An hour after treatment 20% of the ER patients were free of pain and the rest 7.5% VAS 6. The average of VAS before the treatment were 6.38 ± 2.1and an hour after later they decreased to 2.23 ± 1.7. There were only 67.5% of the ER patients that were treated in the 1st hour, 17.5% of them were treated in the 2nd hour, the other 10% were treated in the 3rd hour, and the last 5% of them were treated in the 4th hour. Conclusion:The average value of pain was decreased when one hour after administration of pain therapy by paramedics, but therapy at different times showed no difference in the level of pain reduction that can be inferred.
不受控制的疼痛对身体有许多负面影响。虽然有专门的疼痛管理指南,但急诊室的疼痛评估和治疗还不够充分。治疗前后的综合疼痛评估对监测疼痛管理效果非常重要。目的:研究急诊患者治疗前后的疼痛评分。本研究还记录了急诊室护理人员给出的治疗时间。方法与材料:本研究是一项描述性研究,以Dr. Soetomo医院急诊室的40例创伤患者为样本。在治疗前和治疗后一小时分别测量患者的疼痛程度。采用视觉模拟评分法(VAS)测量疼痛程度。患者给予酮咯酸30mg静脉注射治疗。结果与讨论:评分为1分的占2.5%,评分为10分的占12.5%。治疗1小时后,20%的ER患者无疼痛感,其余患者VAS评分为7.5%。治疗前VAS评分平均值为6.38±2.1,治疗后1 h VAS评分平均值降至2.23±1.7。第1小时就诊的患者仅占67.5%,第2小时就诊的患者占17.5%,第3小时就诊的患者占10%,第4小时就诊的患者占5%。结论:护理人员给予疼痛治疗1小时后,疼痛的平均值有所降低,但不同时间的治疗对疼痛的减轻程度没有差异,可以推断。
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引用次数: 0
Albumin, Leukosit, And Protrombin As Predictors Of Sepsis Mortality Among Adult Patients In Soetomo General Hospital, Surabaya, Indonesia 白蛋白、白细胞和凝血酶作为成年患者脓毒症死亡率的预测因子,印度尼西亚泗水Soetomo总医院
Pub Date : 2019-07-30 DOI: 10.20473/ijar.v1i12019.8-12
Rahmat Sayyid Zharfan, Ahmad Hakim, A. Purba, Soni Sunarso Sulistiawan, B. Semedi
Introduction: Sepsis is presented as a complex and multifactorial syndrome where the morbidity and mortality rates still high around the world. Strong evidencewith regard to early predictive factors for mortality and morbidity is rare to be provided. Objective: The aim of this study was to analyse the prominent predictors from the values of laboratory findings among patients with sepsis. Method and Material: The study was an analytic observational study with a case-control approach. The data were extracted from patients' medical records between 2014 and 2015. This study involved 50 septic patients admitted to Dr. Soetomo General Hospital, Surabaya, Indonesia. Blood urea nitrogen (BUN), creatinine serum, albumin, leukocytes count, haemoglobin, hematocrite, platelets, sodium, potassium, chloride, prothrombin time (PT), and activated partial thromboplastin time (APTT) were collected from blood samples. Logistic regression was used to estimate sepsis related mortalities frequencies and the relationship between laboratory findings and under 28-days mortality. Result and Discussion: From 50 patients, 22 patients were died (44%).The regression model was intially conducted using all three biomarkers as covariates, then using backward elimination, the covariate with the highest p-value was eliminated. The process was repeated until covariates with statistically significant remained. Multivariate analysis showed that albumin, leukocytes count, and prothrombin time (PT) were the findings associated with high mortality. The independent predictors of mortality identified by further multivariate regression analysis were taken into account as a lower than 3.5 g/dL of albumin, above12.000/µL of leukocytes count, and prolonged more than 14 seconds of prothrombin time; with p value <0,05 respectively (0.029; 0.049; 0.027). Conclusion: Notably, low albumin level, elevated levels of leukocytes, and prolonged prothrombin time were clinically considered as independent predictors of mortality among adult patients with sepsis.
简介:脓毒症是一种复杂的多因素综合征,其发病率和死亡率在世界范围内仍然很高。很少有关于死亡率和发病率的早期预测因素的有力证据。目的:本研究的目的是分析脓毒症患者实验室检查值的重要预测因素。方法与材料:本研究为病例对照分析观察性研究。这些数据是从2014年至2015年患者的医疗记录中提取的。本研究涉及印度尼西亚泗水Soetomo综合医院收治的50例脓毒症患者。采集血样中的尿素氮(BUN)、血清肌酐、白蛋白、白细胞计数、血红蛋白、红细胞、血小板、钠、钾、氯、凝血酶原时间(PT)和活化的部分凝血活酶时间(APTT)。使用Logistic回归来估计脓毒症相关的死亡率频率以及实验室结果与28天以下死亡率之间的关系。结果与讨论:50例患者中,22例死亡(44%)。回归模型最初使用所有三种生物标志物作为协变量,然后使用反向消去,消除p值最高的协变量。重复这个过程,直到有统计显著的协变量存在。多变量分析显示,白蛋白、白细胞计数和凝血酶原时间(PT)与高死亡率相关。通过进一步的多因素回归分析确定的死亡率独立预测因素包括:白蛋白低于3.5 g/dL,白细胞计数高于12.000/µL,凝血酶原时间延长超过14秒;p值分别< 0.05 (0.029;0.049;0.027)。结论:值得注意的是,白蛋白水平低、白细胞水平升高和凝血酶原时间延长在临床上被认为是成年脓毒症患者死亡率的独立预测因素。
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引用次数: 2
期刊
Indonesian Journal of Anesthesiology and Reanimation
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