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2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)最新文献

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Key techniques of haptic related computation in virtual liver surgery 虚拟肝脏手术中触觉相关计算的关键技术
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401529
Yifei Shi, Yueshan Xiong, Xiaoqiang Hua, Ke Tan, Xinhua Pan
With or without a realistic haptic effect is the key difference between virtual surgery and the traditional training methods. On the real-time operation stage, users contact with the virtual scene and implement the operation by manipulating the haptic interaction device. Obviously, haptic related computation is the most important part for a virtual surgery system. This paper studied the haptic related computation of the virtual liver surgery, including the mechanism of haptic computation in liver virtual surgery, liver cutting area delineation and liver parenchyma splitting simulation. We developed two novel methods to simulate the delineation and splitting on the virtual liver surface. Results show our techniques can not only provide a realistic effect in our virtual surgery system, but also can be used in other simulation and geometry fields.
有无逼真的触觉效果是虚拟手术与传统训练方法的关键区别。在实时操作阶段,用户通过操纵触觉交互设备与虚拟场景接触,实现操作。显然,触觉相关计算是虚拟手术系统的重要组成部分。本文研究了虚拟肝脏手术的触觉相关计算,包括肝脏虚拟手术中触觉计算的机制、肝脏切割区域的划定和肝脏实质分裂模拟。我们开发了两种新的方法来模拟虚拟肝表面的圈定和分裂。结果表明,我们的技术不仅可以在虚拟手术系统中提供逼真的效果,而且可以应用于其他仿真和几何领域。
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引用次数: 7
Effects of preload, after-load and myocardial contractility on pressure-volume loop of the cardiovascular system model 预负荷、后负荷和心肌收缩力对心血管系统模型压力-容积回路的影响
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401517
Yonghua Lao, Hongke Ji, Yuming Huang, Junwei Liang, Yueshan Huang, Yuhe Li, Zhenyu Zhu, Zhiguan Huang
Studies of cardiovascular system have been the hot point generally concerned as well as extraordinarily significant issue of bioscience. Because of the complexity of cardiovascular system, it is difficult to research the internal principle completely. Consequently, it is usual to study by modeling and simulation. In this article, the cardiovascular system model was established by using Matlab/Simulink. According to the functional test and the evaluation, the results of the model are highly similar to the clinical data, so it can be used widely to simulate various diseases and accidents. Based on the results, we mainly use the model to analyze the effective factors on pressure-volume loop of left ventricle, including preload, after-load and myocardial contractility. In a cardiac cycle, the pressure-volume (P-V) loop of left ventricle will always be in a series of dynamic changes. The pressure-volume relationship of left ventricle is a closed loop that could be used to evaluate the left ventricle's function. Preload, after-load and myocardial contractility always influence the cardiac outputs; the P-V loop will be changed as these factors change. The research focuses on the changes of these three factors and the corresponding changes of the P-V loop.
心血管系统的研究一直是生物科学领域普遍关注的热点和非常重要的问题。由于心血管系统的复杂性,很难对其内部原理进行全面的研究。因此,通常采用建模和仿真的方法进行研究。本文利用Matlab/Simulink建立了心血管系统模型。经功能测试和评价,该模型与临床数据具有较高的相似度,可广泛用于各种疾病和事故的模拟。在此基础上,我们主要利用该模型分析左心室压力-容积环的影响因素,包括前负荷、后负荷和心肌收缩力。在一个心动周期中,左心室压力-容积(P-V)环始终处于一系列动态变化中。左心室压力-容积关系是一个闭环,可用于评价左心室功能。预负荷、后负荷和心肌收缩力都会影响心输出量;P-V回路将随着这些因素的变化而变化。研究的重点是这三个因素的变化以及相应的P-V回路的变化。
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引用次数: 0
Polymer-sandwiched ultra-thin silicon(100) layer for flexible electronics 聚合物夹层超薄硅(100)层,用于柔性电子产品
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401531
Yong-hua Zhang, S. Campbell, Liyuan Zhang
Flexible electronics has gained increasing attention for biomedical engineering applications, solar cell and so on. In this paper, an SU-8/silicon(100)/SU-8 flexible composite sandwich structure is studied. Besides preventing corrosion to the underneath thin silicon membrane, SU-8 photoresist coated on the silicon membrane improves its flexibility as shown by a finite element (FE) simulation utilizing ANSYS software. Using plasma enhanced chemical vapor deposited SiO2/Si3N4 composite film as an etching mask, a 4" silicon(100) wafer was thinned to 26μm without rupture in a 30 wt.% KOH solution. The thinned wafer was coated on both sides with 20μm of SU-8 photoresist and cut into strips. And then the strips were bent by a caliper to measure its radius of curvature. A sector model of bending deformation was adopted to estimate the radius of curvature. The determined minimal bending radius of the polymer-sandwiched ultra-thin silicon layer is no more than 3.3mm. The polymer-sandwiched ultra-thin silicon(100) layer can be used as a flexible substrate. And the fabrication of this sandwich structure is compatible with conventional microelectronic fabrication processing. It can be used as a post-fabrication process for high performance flexible electronics.
柔性电子在生物医学工程、太阳能电池等领域的应用越来越受到人们的关注。本文研究了一种SU-8/硅(100)/SU-8柔性复合材料夹层结构。利用ANSYS软件进行了有限元模拟,结果表明,在硅膜上涂覆的SU-8光刻胶除了可以防止下面的薄硅膜腐蚀外,还可以提高硅膜的灵活性。采用等离子体增强化学气相沉积SiO2/Si3N4复合薄膜作为蚀刻掩膜,在30 wt.% KOH溶液中将4”硅(100)晶圆薄至26μm而不破裂。在薄片两侧涂覆20μm的SU-8光刻胶,并切割成条状。然后用卡尺将这些条弯曲以测量其曲率半径。采用弯曲变形扇形模型估计曲率半径。聚合物夹层超薄硅层的最小弯曲半径不大于3.3mm。聚合物夹层超薄硅(100)层可用作柔性衬底。这种夹层结构的制造与传统的微电子制造工艺相适应。它可以用作高性能柔性电子产品的后加工工艺。
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引用次数: 1
Kinect-based ultrasound probe pose estimation to build an affordable knee ultrasound learning database 基于运动学的超声探头位姿估计,建立可负担的膝关节超声学习数据库
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401554
Amel Ourahmoune, S. Larabi, C. Hamitouche-Djabou, Said Idri, M. Belhadj, Mourad Benallegue
Our aim is to develop an accessible virtual learning environment for ultrasound exams. In this paper, we present an affordable way to localize the ultrasound probe using a Kinect sensor. The proposed localization procedure is coupled with an existing force acquisition schema to affordably associate each ultrasound image to its probe location and the applied force. The collected information is used to build a learning database which is exploited to set up a virtual environment. This virtual ultrasound environment will encourage technology diffusion and will improve the student's accuracy in the ultrasound exam.
我们的目标是为超声检查开发一个可访问的虚拟学习环境。在本文中,我们提出了一种经济实惠的方法来定位超声探头使用Kinect传感器。所提出的定位程序与现有的力获取模式相结合,以经济地将每个超声图像与其探针位置和施加的力联系起来。收集到的信息用于建立学习数据库,并利用该数据库建立虚拟环境。这种虚拟超声环境将促进技术的传播,并将提高学生在超声检查中的准确性。
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引用次数: 0
Intracranial fine simulations based on a four layers craniocerebral model 基于四层颅脑模型的颅内精细模拟
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401466
Yanzhao Gao, Li Ke, Qiang Du, Ling Han
Magnetic induction tomography (MIT) is an effective brain health monitoring system. The application and the data analysis of the MIT system are difficult because of the uneven distribution of intracranial electrical characteristics. To study the effect of the intracranial main ingredients on the MIT signal, a four layers craniocerebral model was put forward in this paper, which was established according to the human physiological structure. First of all, a skull model was established according to the anatomic structure. Structures of the skull model including eyes, occipital bone and frontal bone were revised. And brain parenchyma, cerebral spinal and head cortex were added on that basis. Finally, we analyzed the conductivity characteristics of each part of the organizational structure. The model was put into the MIT system. And the induced current data of the model was gained. It provides a reference for the design of the MIT system.
磁感应断层扫描(MIT)是一种有效的脑健康监测系统。由于颅内电特性分布不均匀,给MIT系统的应用和数据分析带来了困难。为了研究颅内主要成分对MIT信号的影响,本文根据人体生理结构建立了一个四层颅脑模型。首先,根据解剖结构建立颅骨模型。颅骨模型的结构包括眼、枕骨和额骨进行了修正。在此基础上又增加了脑实质、脑脊髓和脑皮层。最后,我们分析了组织结构各部分的电导率特性。该模型被应用于MIT系统。得到了模型的感应电流数据。为MIT系统的设计提供了参考。
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引用次数: 1
Preparation and characteristics of diatrizoate meglumine-loaded chitosan microspheres 壳聚糖微球的制备及性能研究
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401532
Yuming Huang, Yurong Ji, Yonghua Lao, Lan Yao, Jianhui Song, Xia Zhi, Yueshan Huang
The purpose of the present study is to prepare a diatrizoate meglumine-loaded chitosan microsphere, which could be used to be investigated by ultrasonic imaging technique in vivo and would has water absorption swelling property to dredge the obstruction. Diatrizoate meglumine-loaded chitosan microspheres were prepared by crosslink emulsification process, to use chitosan acetic acid solution as aqueous phase, liquid paraffin as oil phase, Span80 and n-butyl alcohol as surfactant, glutaraldehyde solution as crosslink agent. The effect of ratio of diatrizoate meglumine (ratio of W), the ratio of aqueous to organic phase (W/O ratio), the ratio of Span80 to liquid paraffin and the time of crosslink process were optimized by the single factor experiment and response surface experiment. And the optimum prepared microspheres' appearance, distribution, diameter, zeta potential, thermal performance and release properties were measured and their swelling and development properties were observed. The diatrizoate meglumine-loaded chitosan microspheres had a good shape and uniform distribution by light microscope and transmission electron microscope, with average diameters of 1.53 μm and average zeta potential of -19.7 mV; the microspheres had a good sustained release property. And the swelling property of the diatrizoate megiumine-loaded chitosan microspheres varied in different conditions and developed clearly under the ultrasonic imaging technique. This study prepares a kind of diatrizoate meglumine-loaded chitosan microspheres, who can make the microspheres, develop and dredge the obstruction at the same time.
本研究的目的是制备一种可用于超声成像技术在体内研究的异位负载甲氧胺壳聚糖微球,该微球具有吸水膨胀性,可疏通阻塞。以壳聚糖乙酸溶液为水相,液体石蜡为油相,Span80和正丁醇为表面活性剂,戊二醛溶液为交联剂,采用交联乳化法制备了甲酰亚胺负载壳聚糖微球。通过单因素实验和响应面实验,优化了异构体三聚氰胺的配比(W比)、水相与有机相的配比(W/O比)、Span80与液体石蜡的配比以及交联时间的影响。对制备的最佳微球的形貌、分布、直径、zeta电位、热学性能和释放性能进行了测定,并观察了微球的膨胀和显影性能。光镜和透射电镜观察表明,壳聚糖微球的平均直径为1.53 μm,平均zeta电位为-19.7 mV,形状良好,分布均匀;该微球具有良好的缓释性能。在超声成像技术下,不同条件下异位负载的壳聚糖微球的膨胀特性发生了明显的变化。本研究制备了一种异位负载聚氨基甲壳聚糖微球,它能同时制备微球、发育和疏通阻塞。
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引用次数: 0
Simulation studies on erythrocyte passage through a bifurcating microvessel 红细胞通过分叉微血管的模拟研究
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401520
Yihsin Tang, Z. Xing, Tong Wang
This paper presents a numerical model to predict the erythrocyte deformation and motion in a symmetric diverging and converging bifurcation of a microchannel. Membrane mechanics is considered and is incorporated with fluid dynamics. The model has been used to evaluate the effect of different biophysical parameters. The simulation results demonstrate that erythrocytes in microvessels blunt velocity profiles in both straight section and daughter branches. Moreover, the deformation and motion of erythrocytes is strongly influenced by the initial position of the cells, cell stiffness, and shape of the cells. These results may provide fundamental knowledge for a better understanding of hemodynamic behavior of microscale blood flow.
本文提出了一种预测微通道对称发散和收敛分叉中红细胞变形和运动的数值模型。考虑了膜力学,并将其与流体力学相结合。该模型用于评价不同生物物理参数的影响。模拟结果表明,红细胞在微血管直段和子分支上均呈钝化速度分布。此外,红细胞的变形和运动受到细胞的初始位置、细胞刚度和细胞形状的强烈影响。这些结果可能为更好地理解微尺度血流的血流动力学行为提供基础知识。
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引用次数: 1
A fair exchange and track system for RFID-tagged logistic chains rfid标签物流链的公平交换和跟踪系统
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401586
Shouming Chen, Tian Wang, Jieqing Ai
RFID (Radio-Frequency IDentification) is attractive for the strong visibility it provides into logistics operations. In this paper, we explore fair-exchange techniques to encourage honest reporting of item receipt in RFID-tagged supply chains and present a fair ownership transfer system for RFID-tagged supply chains. In our system, a receiver can only access the data and/or functions of the RFID tag by providing the sender with a cryptographic attestation of successful receipt; cheating results in a defunct tag. Conversely, the sender can only obtain the receiver's attestation by providing the secret keys required to access the tag.
RFID(无线射频识别)是有吸引力的,因为它为物流操作提供了强大的可见性。在本文中,我们探讨了公平交换技术,以鼓励在rfid标签供应链中诚实地报告物品收据,并为rfid标签供应链提出了一个公平的所有权转移系统。在我们的系统中,接收方只有向发送方提供成功接收的加密证明,才能访问RFID标签的数据和/或功能;作弊会导致标签失效。相反,发送方只能通过提供访问标签所需的密钥来获得接收方的认证。
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引用次数: 0
The model of Ebola disease control and optimization algorithm of pharmaceutical logistics path 埃博拉疾病控制模型及药品物流路径优化算法
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401617
S. Yan
Ebola is threatening us heavily nowadays, especially in Africa, which means that eradicating Ebola is a tremendous challenge to be faced. It is vital to ensure adequate quantities of Ebola treatment drugs supply to meet the timely and effective elimination of the Ebola epidemic. Ebola treating drug manufacturing and logistics transportation are particularly important and indispensable processes for preventing Ebola's spread. The paper established the control model of Ebola disease and completed the combination of the treatment drug delivery path optimal algorithm. The improved Mathematical Model structure of virus prevalence based on SEIQR is successfully built to eradicate Ebola spread. By Case simulation of Mathematical Model of probability statistics is used to predict the spread of the disease and support the selection of the most efficient transportation path. The improved optimization algorithm of pharmaceutical logistics path based on classical Dijkstra's algorithm is put forward and developed, which finds the fastest and most efficient path recursively by comparing medicine transportation time among transit points. Through the path analysis, we can also know the best locations of medicine delivery. The model with theoretical support and practical significance will be of great help to provide reliable data support and reference for the Health Control Organization to prevent the spread of the Ebola virus.
埃博拉病毒目前正严重威胁着我们,特别是在非洲,这意味着根除埃博拉病毒是一项巨大的挑战。确保足够数量的埃博拉治疗药物供应,以满足及时和有效消除埃博拉疫情的需要至关重要。埃博拉治疗药物制造和物流运输是防止埃博拉传播的特别重要和不可或缺的过程。本文建立了埃博拉疾病的控制模型,完成了结合治疗药物给药路径的优化算法。成功建立了改进的基于SEIQR的病毒流行率数学模型结构,以根除埃博拉病毒的传播。通过实例仿真,利用概率统计数学模型预测疾病的传播,支持选择最有效的运输路径。在经典Dijkstra算法的基础上,提出并发展了一种改进的药品物流路径优化算法,通过比较各转运点之间的药品运输时间,递归地寻找最快、最有效的路径。通过路径分析,我们还可以知道药物输送的最佳位置。该模型具有理论支持和实践意义,将有助于为卫生控制组织预防埃博拉病毒的传播提供可靠的数据支持和参考。
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引用次数: 2
The application of visualization techniques in recommendation systems 可视化技术在推荐系统中的应用
Pub Date : 2015-10-01 DOI: 10.1109/BMEI.2015.7401585
Dong Qian, Cheng Yang, Chen Li
The personalized recommendation system has been widely and maturely applied to various domains from social network to items recommendation such as videos, music, movies, books and online shopping. In the meantime, the information visualization technology based on big data has a substantial development. Considering the common based on big data, this paper discussed the connections of graph visualization and recommendation system from a new perspective. We propose three combinative points: Firstly, the Visual Analytics of social network can be combined with the recommendation computing; secondly, the graph drawing algorithms can be combined with the terminal presentation of recommended results. On the account of the evolutional nature of recommendation, the dynamic graphs would be the key area; thirdly, user interaction with the recommendation system can use the graph interaction strategies to achieve a more accurate and understandable result. In this paper, we discuss the visual techniques which can applied to recommendation system from a more general perspective. We also discuss some research challenges in the future.
个性化推荐系统已经广泛成熟地应用于从社交网络到视频、音乐、电影、书籍、网购等物品推荐的各个领域。与此同时,基于大数据的信息可视化技术有了实质性的发展。考虑到基于大数据的共性,本文从一个新的角度探讨了图形可视化与推荐系统的联系。我们提出了三个结合点:首先,社交网络的可视化分析可以与推荐计算相结合;其次,图形绘制算法可以与推荐结果的终端呈现相结合。考虑到推荐的进化特性,动态图将是关键领域;第三,用户与推荐系统的交互可以使用图形交互策略,以获得更准确和可理解的结果。在本文中,我们从更一般的角度讨论了视觉技术在推荐系统中的应用。我们还讨论了未来的一些研究挑战。
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引用次数: 2
期刊
2015 8th International Conference on Biomedical Engineering and Informatics (BMEI)
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