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The Psychological Impacts and Coping Strategies of People Under 60 Living With Mesothelioma Cancer: A Qualitative Study 60岁以下间皮瘤患者的心理影响及应对策略:一项定性研究
IF 1.9 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-09-24 DOI: 10.1155/ecc/6743766
Benjamin Lond, Iain Williamson, Lindsay Apps, Liz Darlison, Kerry Quincey

Introduction: Mesothelioma is a life-limiting cancer that results in an array of psychological difficulties. While this cancer is associated with older men exposed to asbestos, it can develop in people under 60, though little research has considered the challenges and ways of supporting this younger demographic.

Methods: Online semistructured interviews were carried out one-to-one with a total of 18 individuals; 6 men and 12 women, aged 26–59 (mean age 45), diagnosed with pleural or peritoneal mesothelioma. Participants could also share and discuss photographs to help further convey their cancer experiences. An interpretative phenomenological approach guided the analysis of transcript and photographic data.

Results: Two themes with discrete subthemes are presented: “dying young of an older person’s disease,” which explores individuals’ experiences of shock at diagnosis and widespread sense of disrupted living, concern for family members, and lack of peer support, and “living young with an older person’s disease,” which explores psychobehavioral coping via focus on the atypicality of mesothelioma in young groups, return to everyday living, and via activities and exercise to manage anxiety and foster a sense of agency.

Conclusion: Findings demonstrate the need to develop tailored clinical and psychotherapeutic support to address the practical and psychological difficulties younger people encounter.

间皮瘤是一种限制生命的癌症,导致一系列的心理困难。虽然这种癌症与接触石棉的老年男性有关,但它也可能发生在60岁以下的人群中,尽管很少有研究考虑到支持年轻人群的挑战和方法。方法:采用一对一在线半结构化访谈,共18人;6男12女,年龄26-59岁(平均45岁),诊断为胸膜间皮瘤或腹膜间皮瘤。参加者亦可分享及讨论照片,以进一步传达他们的癌症经历。解释性现象学方法指导了对笔录和摄影数据的分析。结果:提出了两个具有离散子主题的主题:“死于老年人疾病的年轻”,探讨了个人在诊断时的震惊经历和普遍的生活中断感,对家庭成员的关注,以及缺乏同伴支持;“活在老年人疾病的年轻时代”,探讨了心理行为应对,通过关注年轻群体中间皮瘤的非典型性,回归日常生活,通过活动和锻炼来管理焦虑和培养代理感。结论:研究结果表明,需要开发量身定制的临床和心理治疗支持,以解决年轻人遇到的实际和心理困难。
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引用次数: 0
Maternal Quality of Life During Pregnancy and Early Childhood Cancer: A Mixed-Methods Case-Control Study 孕期产妇生活质量与儿童早期癌症:一项混合方法病例对照研究
IF 1.9 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-09-24 DOI: 10.1155/ecc/3235446
Behnaz Aflatoonian, Hossein Mirzaei, Morteza Hashemian, Mohammad Reza Aflatoonian

Introduction: This study investigates the relationship between maternal quality of life during pregnancy and childhood cancer risk, hypothesizing that lower maternal well-being increases the likelihood of cancer development in children.

Methods: This embedded explanatory sequential mixed-methods case-control study was conducted in Kerman, Iran, including 191 children under six, with 136 diagnosed with cancer in 2023. From these, 73 mothers of affected children were purposefully selected and compared to 118 mothers of healthy children, matched by age and socioeconomic status. Maternal factors (e.g., age, education, employment, medical history, and lifestyle) were assessed using validated questionnaires (GHQ-28, SES), administered through structured interviews. Logistic regression (SPSS 28) and Python-based heatmap visualization were used for analysis. Qualitative data were extracted from interview narratives and analyzed thematically.

Results: Between 2014 and 2023, pediatric cancer diagnoses increased, especially malignant types. Significant maternal factors included older age, unemployment, lower education, medical history, and smoking. Paternal education, occupational exposure, and smoking also contributed. Qualitative themes—persistent anxiety, depressive thoughts, and perceived lack of purpose—offered contextual depth to the statistical findings.

Conclusions: Maternal quality of life during pregnancy significantly influences childhood cancer risk. Integrated interventions addressing maternal mental health, socioeconomic disparities, and occupational exposures are essential. Public health policies should prioritize maternal well-being to create protective environments for children.

本研究调查了怀孕期间母亲生活质量与儿童癌症风险之间的关系,并假设较低的母亲幸福感会增加儿童癌症发展的可能性。方法:这项嵌入式解释性序列混合方法病例对照研究在伊朗Kerman进行,包括191名6岁以下儿童,其中136名在2023年被诊断为癌症。有目的地从中选择73名受影响儿童的母亲,并与118名健康儿童的母亲进行比较,按年龄和社会经济地位进行匹配。使用有效问卷(GHQ-28, SES)通过结构化访谈对产妇因素(如年龄、教育、就业、病史和生活方式)进行评估。采用Logistic回归(SPSS 28)和基于python的热图可视化进行分析。从访谈叙述中提取定性数据并进行主题分析。结果:2014 - 2023年,儿童癌症诊断率上升,尤其是恶性类型。显著的母亲因素包括年龄较大、失业、教育程度较低、病史和吸烟。父亲的教育、职业暴露和吸烟也有影响。定性主题——持续的焦虑、抑郁的想法和感知到的缺乏目标——为统计结果提供了上下文深度。结论:孕期孕产妇生活质量显著影响儿童癌症风险。针对孕产妇心理健康、社会经济差异和职业暴露的综合干预措施至关重要。公共卫生政策应优先考虑产妇福祉,为儿童创造保护性环境。
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引用次数: 0
Systemic and Dynamic Analysis of Access to Health Care: The Example of Hematological Cancer in France 医疗服务可及性的系统动态分析:以法国血液病癌症为例
IF 1.9 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-09-18 DOI: 10.1155/ecc/3641026
Milhan Chaze, Laurent Mériade, Corinne Rochette, Stephanie Malartre-Sapienza, Anne Sophie Michallet

Objective: Access to health care aims to improve people’s health and reduce inequalities. This is a fundamental health policy concern. Over the past 40 years, research has identified several dimensions of access to health care but has often overlooked their interconnections. Based on a mixed geographical and relational method, our article aims to propose a systemic and dynamic analysis of the main dimensions of access to care.

Methods: The population studied in this work consists of all 364 hematological cancer patients. In the first step, we map the movements of these patients in order to categorize them according to their ease of access to care. In the second step, we conduct semistructured interviews to identify nonspatial dimensions of access to care.

Results: Our theoretical results focus on identifying the main links and articulations between dimensions of access to care. They confirm the importance of geographical accessibility in access to care, but, in a more original way, they show the central role of acceptability (confidence in healthcare professionals), itself determined by awareness.

Conclusion: This study suggests that policies to improve access to care should be accompanied by the development of patient awareness and acceptability. In practice, this can be achieved by combining tools such as cooperation between hospitals and healthcare professionals, professional networks, telemedicine, and local hospital accreditation.

目标:获得保健的目的是改善人们的健康和减少不平等。这是一个基本的卫生政策问题。在过去的40年里,研究已经确定了获得卫生保健的几个方面,但往往忽视了它们之间的相互联系。基于混合的地理和关系方法,本文旨在对医疗可及性的主要维度进行系统和动态的分析。方法:本组研究对象为364例血液学肿瘤患者。在第一步,我们绘制这些病人的运动图,以便根据他们获得护理的容易程度对他们进行分类。在第二步,我们进行半结构化访谈,以确定获得护理的非空间维度。结果:我们的理论结果侧重于确定获得护理的维度之间的主要联系和衔接。它们证实了地理可及性在获得保健方面的重要性,但是,它们以一种更原始的方式显示了可接受性(对保健专业人员的信心)的核心作用,而可接受性本身是由认识决定的。结论:本研究提示,改善医疗可及性的政策应伴随着患者意识和可接受性的发展。在实践中,这可以通过结合医院和保健专业人员之间的合作、专业网络、远程医疗和地方医院认证等工具来实现。
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引用次数: 0
Evaluation of a Mobile Application Based on Enhanced Recovery After Surgery Recommendations to Support Patients Undergoing Colorectal Surgery: A Pilot Study 基于增强术后恢复的移动应用程序的评估,以支持接受结肠直肠癌手术的患者:一项试点研究
IF 1.9 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-09-16 DOI: 10.1155/ecc/8896217
Pia Buch Nørgaard, Marian Christin Petersen

Aims and Objectives: The aim is to evaluate the effect of a recently developed mobile application consisting of information, tasks, and gamification has had for patients undergoing colorectal surgery.

Background: Patients undergoing colorectal surgery are recommended to follow enhanced recovery after surgery (ERAS) guidelines. Yet, patients do not always follow ERAS recommendations. Patients express that they would like to have information about their course, that information material must be available at different times, and that too many papers and pamphlets can seem confusing and overwhelming.

Design: In this comparative nonrandomized pilot study, a mobile application is evaluated. Thirty-eight adult patients divided into intervention and control groups were included the study. Quantitative and qualitative methods were used.

Methods: Both groups answered questionnaires before discharge after surgery. Demographic data, The Preparedness for Colorectal Cancer Surgery Questionnaire Subsequently (PCSQ-PRE_24), intake of protein drink, and the degree of mobilization were collected. Four patients from the intervention group participated in a focus group interview. The STROBE cohort checklist was used.

Results: The study showed significant difference in favor of the intervention group in PCSQ-PRE_24: subtheme understanding and involvement in care processes p = 0.043 and total score p = 0.034 as well as intake of protein drink showed significant difference p = 0.012. There was no significant difference in terms of mobilization. The patients stated that the mobile application was easy to use and made them secure through their surgical procedure.

Conclusion: The results from this pilot study showed that patients undergoing colorectal surgery benefit from a tool in the form of a mobile application that can guide them through their surgical procedure.

目的和目的:目的是评估最近开发的由信息、任务和游戏化组成的移动应用程序对接受结直肠手术的患者的影响。背景:建议接受结直肠手术的患者遵循术后增强恢复(ERAS)指南。然而,患者并不总是遵循ERAS的建议。患者表示,他们希望了解自己的病程,信息材料必须在不同的时间提供,而太多的文件和小册子似乎令人困惑和压倒性的。设计:在这个比较的非随机试点研究中,评估了一个移动应用程序。38名成年患者被分为干预组和对照组。采用定量和定性相结合的方法。方法:两组患者均在术后出院前进行问卷调查。收集人口统计学资料、结肠直肠癌手术准备问卷(PCSQ-PRE_24)、蛋白饮料摄入量、运动程度。干预组4例患者参加焦点小组访谈。采用STROBE队列检查表。结果:干预组在PCSQ-PRE_24的子主题理解和护理过程参与p = 0.043,总得分p = 0.034,蛋白饮料摄入p = 0.012方面存在显著差异。在动员方面没有显著差异。患者表示,该移动应用程序易于使用,并使他们在手术过程中保持安全。结论:这项初步研究的结果表明,接受结直肠手术的患者受益于一种移动应用程序形式的工具,可以指导他们完成手术过程。
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引用次数: 0
Corrigendum to “Anxiety and Depression in Patients Receiving Haematopoietic Stem Cell Transplantation and Their Caregivers: A Dyadic Longitudinal Study” “接受造血干细胞移植的患者及其护理人员的焦虑和抑郁:一项双纵向研究”的勘误表
IF 1.9 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-09-11 DOI: 10.1155/ecc/9874193

A. Rosich-Soteras, C. Ramos-Serrano, A. Serrahima-Mackay, et al., “Anxiety and Depression in Patients Receiving Haematopoietic Stem Cell Transplantation and Their Caregivers: A Dyadic Longitudinal Study,” European Journal of Cancer Care 2025 (2025): 5744882, https://doi.org/10.1155/ecc/5744882.

In the article titled “Anxiety and Depression in Patients Receiving Haematopoietic Stem Cell Transplantation and Their Caregivers: A Dyadic Longitudinal Study,” an affiliation was omitted in error. This affiliation has been added to the affiliation list below as number 2, and the correct author list and their affiliations are shown below.

Arianna Rosich-Soteras1,2, Carla Ramos-Serrano1, Anna Serrahima-Mackay1, Cristina Gallego Miralles1, Teresa Solano Moliner1, Núria Jaramillo Forcada1, Laia Guardia Roca1, Ariadna Domenech1, and Adelaida Zabalegui2,3

1Institute of Cancer and Blood Diseases, Hospital Clínic Barcelona, Barcelona, Spain

2Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Carrer Casanova, 143, 08036 Barcelona, Spain

3Nursing Management Department, Hospital Clínic Barcelona, Barcelona, Spain

We apologize for this error.

A. Rosich-Soteras, C. Ramos-Serrano, A. Serrahima-Mackay等,“接受造血干细胞移植患者及其护理人员的焦虑和抑郁:一项双纵向研究”,欧洲癌症护理杂志2025 (2025):5744882,https://doi.org/10.1155/ecc/5744882.In,题为“接受造血干细胞移植患者及其护理人员的焦虑和抑郁:一项双纵向研究”的文章因错误而被省略。这个隶属关系已被添加到下面的隶属关系列表中,编号为2,正确的作者列表及其隶属关系如下所示。Arianna rosich - soteras1,2, Carla Ramos-Serrano1, Anna Serrahima-Mackay1, Cristina Gallego Miralles1, Teresa Solano Moliner1, Núria西班牙巴塞罗那医院Clínic癌症和血液疾病研究所Jaramillo forcad1, Laia Guardia Roca1, Ariadna Domenech1和Adelaida Zabalegui2,31西班牙巴塞罗那医院Clínic巴塞罗那医院癌症和血液疾病研究所2巴塞罗那大学Carrer Casanova医学院,143,08036西班牙巴塞罗那3巴塞罗那医院护理管理部门Clínic我们为这个错误道歉。
{"title":"Corrigendum to “Anxiety and Depression in Patients Receiving Haematopoietic Stem Cell Transplantation and Their Caregivers: A Dyadic Longitudinal Study”","authors":"","doi":"10.1155/ecc/9874193","DOIUrl":"https://doi.org/10.1155/ecc/9874193","url":null,"abstract":"<p>A. Rosich-Soteras, C. Ramos-Serrano, A. Serrahima-Mackay, et al., “Anxiety and Depression in Patients Receiving Haematopoietic Stem Cell Transplantation and Their Caregivers: A Dyadic Longitudinal Study,” <i>European Journal of Cancer Care</i> 2025 (2025): 5744882, https://doi.org/10.1155/ecc/5744882.</p><p>In the article titled “Anxiety and Depression in Patients Receiving Haematopoietic Stem Cell Transplantation and Their Caregivers: A Dyadic Longitudinal Study,” an affiliation was omitted in error. This affiliation has been added to the affiliation list below as number 2, and the correct author list and their affiliations are shown below.</p><p>Arianna Rosich-Soteras<sup>1,2</sup>, Carla Ramos-Serrano<sup>1</sup>, Anna Serrahima-Mackay<sup>1</sup>, Cristina Gallego Miralles<sup>1</sup>, Teresa Solano Moliner<sup>1</sup>, Núria Jaramillo Forcada<sup>1</sup>, Laia Guardia Roca<sup>1</sup>, Ariadna Domenech<sup>1</sup>, and Adelaida Zabalegui<sup>2,3</sup></p><p><sup><i>1</i></sup><i>Institute of Cancer and Blood Diseases, Hospital Clínic Barcelona, Barcelona, Spain</i></p><p><sup><i>2</i></sup><i>Facultat de Medicina i Ciències de la Salut, Universitat de Barcelona (UB), Carrer Casanova, 143, 08036 Barcelona, Spain</i></p><p><sup><i>3</i></sup><i>Nursing Management Department, Hospital Clínic Barcelona, Barcelona, Spain</i></p><p>We apologize for this error.</p>","PeriodicalId":11953,"journal":{"name":"European Journal of Cancer Care","volume":"2025 1","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ecc/9874193","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145051126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Role That a Helpline Could Play for People Diagnosed With Sarcoma and Their Carers 探索帮助热线对被诊断为肉瘤的人及其护理人员的作用
IF 1.9 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-09-09 DOI: 10.1155/ecc/5633734
Georgia K. B. Halkett, Connor Farnell, Melissa Berg, Mandy Basson, Moira O’Connor

Background: Sarcoma represents a group of cancers that carry a disproportionate impact on the well-being of people who are diagnosed and carers. Unlike more common cancers, limited tumour-specific support exists for people with sarcoma and carers. The aim of this study was to explore the potential role a telephone helpline could play in supporting people diagnosed with sarcoma and carers.

Methods: This study utilised an exploratory qualitative approach with a social constructionist framework. Semistructured interviews were conducted with people diagnosed with sarcoma, carers, bereaved carers and health professionals. Reflexive thematic analysis was conducted to determine themes.

Results: 43 semistructured interviews were conducted with people with sarcoma (n = 12), carers (n = 11), bereaved carers (n = 4) and health professionals (n = 16). Five themes were identified: ‘the current system is not meeting needs,’ ‘holistic support,’ ‘a source of credible information,’ ‘the helpline operator’ and ‘centralised support for my sarcoma.’

Conclusion: Significant unmet needs continue to exist for people diagnosed with sarcoma and carers. A community support helpline was conceptualised as a helpful and effective tool for meeting the medical, psychosocial and information needs of all people impacted by sarcoma.

背景:肉瘤代表了一组癌症,对被诊断者和护理者的福祉产生不成比例的影响。与更常见的癌症不同,针对肉瘤患者和护理人员的肿瘤特异性支持有限。这项研究的目的是探索电话热线在帮助肉瘤患者和护理人员方面的潜在作用。方法:本研究采用社会建构主义框架下的探索性定性研究方法。对被诊断为肉瘤的人、护理人员、失去亲人的护理人员和卫生专业人员进行了半结构化访谈。通过反身性主位分析来确定主位。结果:对43名肉瘤患者(n = 12)、护理人员(n = 11)、失去亲人的护理人员(n = 4)和卫生专业人员(n = 16)进行了半结构化访谈。他们确定了五个主题:“目前的系统不能满足需求”、“整体支持”、“可靠信息的来源”、“热线接线员”和“对我的肉瘤的集中支持”。结论:对于被诊断为肉瘤的患者和护理人员来说,显著的未满足需求仍然存在。社区支持热线的概念是作为满足所有受肉瘤影响的人的医疗、社会心理和信息需求的有用和有效的工具。
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引用次数: 0
Cancer Cachexia in Clinical Practice: A Review of Treatment Barriers Among Cancer Patients 临床实践中的癌症恶病质:癌症患者治疗障碍的综述
IF 1.9 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-09-07 DOI: 10.1155/ecc/6659047
Naema Alamawi, Anas Alsharawneh, Hasan Abualruz, Salah M. AbuRuz

Background: Cancer cachexia is a multifactorial syndrome that affects patients’ quality of life and survival. It accounts for over 20% of cancer deaths. Despite its high incidence, there is no evidence-based standard of care for managing it. Early detection and management require preventative measures and multimodal therapy.

Aim: The purpose of this study was to conduct an in-depth review of the literature on cancer cachexia and its barriers for effective assessment and management.

Methods: The literature review was conducted through various electronic databases to identify studies published on cancer cachexia and its barriers for effective assessment and management of cancer cachexia.

Results: The review indicated that barriers for effective assessment and management of cancer cachexia were on three levels: patients, health workers, and organizations. Also, there is a knowledge gap in understanding, assessing, and managing cancer cachexia among healthcare workers, patients, and family members.

Conclusion: The research indicates that patients, family members, and healthcare professionals lack sufficient knowledge about how to identify, assess, and treat cancer cachexia. This gap has a lot of important barriers, both modifiable and nonmodifiable. Patients, healthcare professionals, and organizations are the three levels of those barriers.

背景:癌症恶病质是一种影响患者生活质量和生存的多因素综合征。它占癌症死亡人数的20%以上。尽管它的发病率很高,但没有基于证据的护理标准来管理它。早期发现和管理需要预防措施和多模式治疗。目的:本研究的目的是对癌症恶病质及其障碍进行深入的文献综述,以便有效的评估和管理。方法:通过各种电子数据库进行文献综述,找出已发表的关于癌症恶病质的研究及其障碍,为癌症恶病质的有效评估和管理提供参考。结果:本综述指出,有效评估和管理癌症恶病质的障碍存在于三个层面:患者、卫生工作者和组织。此外,在医护人员、患者和家属之间,对癌症恶病质的理解、评估和管理方面也存在知识差距。结论:研究表明,患者、家属和医护人员对如何识别、评估和治疗癌症恶病质缺乏足够的知识。这个差距有很多重要的障碍,包括可修改的和不可修改的。患者、医疗保健专业人员和组织是这些障碍的三个层次。
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引用次数: 0
Navigating the Burden: A Systematic Review of Children and Young People Caring for Family Members With Cancer 导航负担:儿童和青少年照顾患有癌症的家庭成员的系统回顾
IF 1.9 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-09-04 DOI: 10.1155/ecc/7213292
Wendy McInally, Elena Alder, Eva Schellenberg, Jo Horne, Agnes Leu, Kerry Jones, Joseph De-Lappe, Jitka Vseteckova

Introduction: In 2025, one in two adults will be diagnosed with cancer. This is challenging for all people affected by cancer, including the children and young people within the family unit, and it can affect their physical, emotional and social well-being. However, little is known about the support and needs of children and young people who are caring for someone within the family with a cancer diagnosis.

Methods: Five databases (MEDLINE, CINAHL, Web of Science, PsycINFO and PubMed), assorted repositories, government reports and websites were searched from 1993 to 2025. All research studies in English, German and French were included and restricted to children and young people aged five to 25 years who care for a family member regularly. A team of independent reviewers made the inclusion and quality assessments using the MMAT standardised critical appraisal tool.

Results: Thirty-four papers were initially considered eligible, with fourteen being disregarded. The themes identified within the literature were (1) ‘Need for support’, (2) ‘Support available’ and (3) ‘Changing roles’.

Discussion and Recommendations: Although in some situations, the children and young people were able to cope with the heavy burden of being a carer, most studies reported a lack of support and several needs, for example, a lack of knowledge on how to care for their parent with cancer and need for support from their peers. In other situations where the cared-for person was dying, the addition of palliative care and end-of-life care was challenging. Although this experience led to not a good death, the young carer was left with a significant loss and no purpose for their own life.

到2025年,每两个成年人中就有一个被诊断出患有癌症。这对所有受癌症影响的人来说都是一个挑战,包括家庭中的儿童和年轻人,它会影响他们的身体、情感和社会福祉。然而,对于照顾患有癌症的家庭成员的儿童和年轻人的支持和需求,人们知之甚少。方法:检索1993 - 2025年的MEDLINE、CINAHL、Web of Science、PsycINFO和PubMed 5大数据库、各类资源库、政府报告和网站。所有用英语、德语和法语进行的研究都纳入了研究对象,并且仅限于经常照顾家庭成员的5至25岁的儿童和年轻人。一组独立审查人员使用MMAT标准化关键评估工具进行了纳入和质量评估。结果:34篇论文最初被认为符合条件,14篇被忽略。在文献中确定的主题是(1)“需要支持”,(2)“可用支持”和(3)“角色转变”。讨论和建议:虽然在某些情况下,儿童和年轻人能够应付作为照顾者的沉重负担,但大多数研究报告缺乏支持和一些需求,例如,缺乏如何照顾患有癌症的父母的知识,需要同龄人的支持。在其他情况下,被照顾的人是垂死的,增加姑息治疗和临终关怀是具有挑战性的。虽然这段经历导致了一个不愉快的死亡,但年轻的照顾者留下了重大的损失,也没有了自己的生活目标。
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引用次数: 0
Path Analysis of Influencing Factors for Financial Toxicity in Patients With Lung Cancer 肺癌患者金融毒性影响因素的通径分析
IF 1.9 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-08-19 DOI: 10.1155/ecc/6591289
Kerui Li, Zefang Long, Meng Luo, Junying Li, Qianqian Mou

Background: The impact of financial toxicity is extensive and far-reaching, even affecting the prognosis of patients with lung cancer. While the influence of sociodemographic factors on financial toxicity in patients with lung cancer has been identified, the exploration of the impact of psychosocial factors remains insufficient.

Aims: This study aims to explore the influencing factors and their pathways of financial toxicity in patients with lung cancer.

Methods: This was a cross-sectional study that utilized a convenience sampling method to select hospitalized patients with lung cancer as research population from a tertiary hospital in Sichuan Province between May and November 2023. Investigations were conducted using a general information questionnaire, Comprehensive Scores for Financial Toxicity, Social Support Rating Scale, and General Self-Efficacy Scale. Data analysis was performed using descriptive analysis, Mann–Whitney U test, Kruskal–Wallis H test, Spearman correlation analysis, stepwise linear regression analysis, and path analysis.

Results: The influencing factors of financial toxicity in patients with lung cancer include age, family income, commercial insurance coverage, social support, and self-efficacy. Furthermore, family income and social support have indirect effects on financial toxicity, while self-efficacy mediates the relationship between social support and financial toxicity.

Conclusion: The financial toxicity experienced by patients with lung cancer should be taken seriously. In clinical practice, healthcare professionals should promptly assess the level of financial toxicity in patients with lung cancer and implement personalized and diversified intervention measures to address it.

背景:金融毒性的影响广泛而深远,甚至影响肺癌患者的预后。虽然已经确定了社会人口因素对肺癌患者财务毒性的影响,但对社会心理因素影响的探索仍然不足。目的:探讨肺癌患者金融毒性的影响因素及其途径。方法:采用横断面研究,采用方便抽样方法,选取四川省某三级医院2023年5 - 11月肺癌住院患者作为研究人群。调查采用一般信息问卷、财务毒性综合评分、社会支持评定量表和一般自我效能量表进行。数据分析采用描述性分析、Mann-Whitney U检验、Kruskal-Wallis H检验、Spearman相关分析、逐步线性回归分析和通径分析。结果:肺癌患者财务毒性的影响因素包括年龄、家庭收入、商业保险覆盖率、社会支持和自我效能感。此外,家庭收入和社会支持对财务毒性有间接影响,而自我效能感在社会支持和财务毒性之间起中介作用。结论:肺癌患者的经济毒性应引起重视。在临床实践中,医疗保健专业人员应及时评估肺癌患者的财务毒性水平,并实施个性化和多样化的干预措施来解决这一问题。
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引用次数: 0
Fatigue and Co-Occurring Cancer-Related Symptoms in Breast Cancer Survivors: A Systematic Review and Network Meta-Analysis 乳腺癌幸存者的疲劳和共同发生的癌症相关症状:系统回顾和网络荟萃分析
IF 1.9 4区 医学 Q3 HEALTH CARE SCIENCES & SERVICES Pub Date : 2025-08-19 DOI: 10.1155/ecc/6615635
Chih-Chieh Huang, Yu-Hsu Liu, Yi-Shiung Horng

Objective: The relative strength of risk factors for cancer-related fatigue (CRF) among breast cancer survivors (BCSs) remains unclear. This study aims to systematically evaluate and compare the strength of different risk factors for CRF using a network meta-analysis (NMA) approach.

Methods: This NMA included observational studies on female BCSs with extractable data related to risk factors for CRF. The PubMed, Cochrane Library, and Embase databases were systematically searched, and the study protocol was registered in PROSPERO (reference no. CRD42025642021). A random-effects meta-analysis was performed to estimate pooled effect sizes, and an NMA with P-scores was used to rank the relative strength of risk factors. Subgroup analyses, sensitivity analyses, and meta-regression were conducted to assess methodological quality and explore potential sources of heterogeneity.

Results: Thirty observational studies (n = 36,302 female BCSs) that were published between 2004 and 2024 were included in this NMA. Depression exhibited the strongest association with CRF (OR = 3.34, 95% CI 2.50–4.46, P-score = 0.9727), followed by insomnia (OR = 2.35, 95% CI 1.45–3.81, P-score = 0.6549), pain (OR = 1.94, 95% CI 1.33–2.84, P-score = 0.4587), and anxiety (OR = 1.85, 95% CI 1.23–2.79, P-score = 0.4132). Subgroup analysis revealed that the associations of the four risk factors with CRF remained significant at the three posttreatment time points (< 1 year, 1–5 years, and > 5 years), with the exception of anxiety and insomnia at < 1 year and pain at > 5 years. Meta-regression demonstrated that higher study quality (measured via the Newcastle–Ottawa scale [NOS]) was significantly correlated with stronger associations of anxiety and insomnia with CRF (β = 0.305 and 0.221, p < 0.05, respectively). Sensitivity analysis confirmed the robustness of the main findings.

Conclusion: Depression plays a central role in CRF development and should be prioritized in survivorship care. Integrating multimodal interventions for depression, sleep disturbances, and pain management may improve fatigue outcomes.

目的:乳腺癌幸存者(BCSs)癌症相关疲劳(CRF)危险因素的相对强度尚不清楚。本研究旨在运用网络元分析(NMA)方法,系统评估和比较不同风险因素对慢性心力衰竭的影响。方法:该NMA纳入了女性bcs的观察性研究,并提供了与CRF危险因素相关的可提取数据。系统检索PubMed、Cochrane Library和Embase数据库,研究方案在PROSPERO中注册(参考文献号:CRD42025642021)。随机效应荟萃分析用于估计合并效应大小,并使用带有p值的NMA对危险因素的相对强度进行排序。进行亚组分析、敏感性分析和meta回归来评估方法学质量并探索潜在的异质性来源。结果:2004年至2024年间发表的30项观察性研究(n = 36302名女性bcs)被纳入该NMA。抑郁与CRF的相关性最强(OR = 3.34, 95% CI 2.50-4.46, P-score = 0.9727),其次是失眠(OR = 2.35, 95% CI 1.45-3.81, P-score = 0.6549)、疼痛(OR = 1.94, 95% CI 1.33-2.84, P-score = 0.4587)和焦虑(OR = 1.85, 95% CI 1.23-2.79, P-score = 0.4132)。亚组分析显示,在治疗后3个时间点(1年、1 - 5年和5年),除焦虑和失眠1年和疼痛5年外,4种危险因素与CRF的相关性仍然显著。meta回归显示,较高的研究质量(通过Newcastle-Ottawa量表[NOS]测量)与焦虑和失眠与CRF的强相关性显著相关(β = 0.305和0.221,p < 0.05)。敏感性分析证实了主要发现的稳健性。结论:抑郁症在CRF的发展中起核心作用,应优先考虑生存护理。整合多模式干预抑郁症、睡眠障碍和疼痛管理可以改善疲劳的结果。
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European Journal of Cancer Care
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