European journal of physical and rehabilitation medicine最新文献

Background: The effect of rehabilitation therapy on health-related quality of life (HRQOL) among patients with brain tumors has not been fully investigated.

Aim: This study aimed to evaluate the effect of rehabilitation therapy on HRQOL among patients with brain tumors using the HRQOL index. We also examined factors that influenced changes in HRQOL, including differences in brain tumor type.

Design: Prospective cohort study.

Setting: University Medical and Dental Hospital.

Population: Patients with brain tumors aged 20 years or older undergoing rehabilitation therapy were included. Patients with cognitive decline, aphasia, or poor general condition who had difficulty answering HRQOL questions were excluded.

Methods: The EuroQol-5 Dimension 5-Level (EQ-5D-5L), EORTC Quality of Life Questionnaire Core 30 (QLQ-C30), and EORTC Quality of Life Questionnaire Brain Cancer Module (BN20) were used to assess HRQOL before and after rehabilitation treatment. Brain tumor type was classified into five groups: World Health Organization (WHO) grade 1, WHO grade 2/3, WHO grade 4, primary central nervous system lymphoma, and metastatic brain tumor. We compared EQ-5D-5L index scores and QLQ-C30 and BN20 scores before and at the end of rehabilitation. Multiple regression analysis was used to examine factors affecting changes in EQ-5D-5L index score (EQ-5D-5L gain).

Results: In total, 112 patients participated in this study. The median EQ-5D-5L index score significantly improved from 0.698 before rehabilitation to 0.772 at the end of rehabilitation (P<0.001, r=0.46). QLQ-C30 and BN20 scores showed significant improvement in physical functioning, global health status, pain, and motor dysfunction (P<0.001, r>0.3). Multiple regression analysis revealed that recurrence (β=-0.191, P=0.037) and baseline EQ-5D-5L index score (β=-0.595, P<0.001) affected EQ-5D-5L gain, whereas differences in brain tumor type did not.

Conclusions: HRQOL among patients with brain tumors improved at the end of rehabilitation therapy compared with before therapy. Furthermore, the EQ-5D-5L index score gain was not affected by brain tumor type.

Clinical rehabilitation impact: These results suggest rehabilitation therapy may contribute to improved HRQOL irrespective of brain tumor type.

Background: Obstetric brachial plexus injury (OBPI) is associated with several temporary or permanent impairments including muscle weakness/atrophy and retarded bone accrual, which negatively affect upper extremity functionality. Thus, to remedy these impairments, improved and unequivocally effective intervention strategies are required.

Aim: To evaluate the effectiveness of a 12-week stretch-shortening cycle exercise (SSC-Ex) program on muscle strength, bone mineral density, and upper extremity function in a convenience sample of children with OBPI.

Design: A prospective, dual-group randomized controlled trial with the outcome assessor being blinded to the treatment allocation.

Population: Fifty-six children with a confirmed diagnosis of the upper-arm type of OBPI (i.e. categorized as level I [C5/C6 injury] or II [C5/C6/C7 injury] per Narakas classification system) and aged between 10 and 16 years were randomly allocated to either the SSC-Ex group (N.=28) or the control group (N.=28).

Methods: The SSC-Ex group participants underwent a supervised SSC-Ex regimen for ~35 minutes, twice/week (with 2-day recovery intervals at minimum) over 12 consecutive weeks (totaling 24 sessions), while the control received the standard exercises (equated for the training volume, frequency, and duration). The primary outcomes included an assessment of muscle strength - specifically, shoulder flexors, abductors, external rotators, elbow flexors, and extensors - as well as the bone mineralization of the humerus, radius, and ulna. Functional performance was considered as a secondary outcome. These measures were undertaken both pre- and post-intervention.

Results: The SSC-Ex group exhibited favorable pre-to-post improvement in muscle strength measures (P<0.05; η²partial ranged between 0.11 and 0.17), bone mineralization variables (P<0.05; η²partial ranged between 0.13 and 0.21), and functional performance (P=0.006; η²partial=0.13) when compared with the control group.

Conclusions: The SSC-Ex showed promise in enhancing strength, bone mineralization, and functional capacity in children with OBPI.

Clinical rehabilitation impact: The SSC-Ex can be a beneficial component of the rehabilitation program for children with OBPI. Physical rehabilitation specialists might opt for such a training paradigm to improve several aspects of motor functions, bone mineral properties, and upper extremity function based on empirical evidence.

Background: Advanced chronic kidney disease disrupts the delicate equilibrium between protein anabolism and catabolism, leading to alterations in muscle quantity, quality, and function. Musculoskeletal ultrasound emerges as a promising assessment tool due to its widespread availability and high reliability.

Aim: To evaluate the efficacy of rectus femoris (RF) echogenicity, measured using greyscale software, in identifying diminished muscle quality and strength in candidates for kidney transplant.

Design: Post-hoc diagnostic accuracy study.

Setting: Outpatients in a multimodal prehabilitation program pre kidney transplantation (KT).

Population: Patients on the waiting list for KT.

Methods: Sensitivity, specificity, likelihood ratios and area under the curve (AUC) for diagnostic efficacy of echogenicity (index test) assessed with the ImageJ software greyscale as a potential marker of quadriceps muscle weakness (reference test) were calculated. Muscle weakness was considered as maximal voluntary isometric contraction of the quadriceps (Q-MVIC) <40% of body weight. Other variables included body composition parameters derived from multifrequency electrical bioimpedance, upper limb muscle strength (handgrip), and RF thickness assessed by ultrasound. Statistical tests: Chi-square, t-Student, Pearson correlation coefficients (r), bivariate and multivariate logistic regression models. Statistical significance level ≤0.05.

Results: Of 112 patients (mean age: 63.6, 76% male), 72 (63.7%) exhibited quadriceps weakness, while 80 (70.8%) had some degree of overhydration (extracellular water/total body water ratio >0.390). The echogenicity cut-off point of highest concordance with muscle weakness was 70, boasting a sensitivity of 83%, specificity of 57%, and AUC of 0.671 (CI 95% 0.570-0.772 [P=0.003]). Echogenicity >70 was associated with a 3.4-fold higher risk of muscle weakness (crude OR = 3.4 [CI95% 1.4 to 8.0]), which persisted after adjusting for age, height, weight and RF thickness.

Conclusions: The RF echogenicity exhibits fair validity in identifying muscle weakness among candidates for KT. However, it cannot be endorsed as a standalone diagnostic tool in this population.

Clinical rehabilitation impact: Early identification of muscle weakness would advance efforts to mitigate morbidity and mortality through targeted measures.

Background: The role of motivation per se in the presence or absence of depression in stroke-related cognitive and functional motor recovery has not been studied.

Aim: This study aimed to determine the role of motivation on cognition and functional motor recovery in patients after an acute and subacute ischemic stroke.

Design: Prospective, observational, single-center study.

Setting: Enrollment was undertaken in an inpatient neurorehabilitation facility.

Population: A total of 125 veterans with stroke were admitted to an inpatient neurorehabilitation facility.

Methods: Recovery locus of control (RLOC) measured the degree of motivation. The primary outcome measures were changes from baseline in the Action Research Arm Test (ARAT), total and sub-scores of Functional Independence Measures (TFIM), and the 2-minute walk test (2-MWT) on discharge from the IRF.

Results: The mean age of the study sample was 65±9.3 years, they were mainly non-Hispanic white (N.=92, 74%) men (N.=119, 95%) admitted 9±11 days after acute stroke. When the sample was divided into less motivated (score 0-25, N.=32) and motivated (score ≥ 26, N.=93) as measured by the total RLOC for a statistical median of 26, the two groups had similar baseline characteristics including admission depression, TFIM, ARAT, and 2-MWT scores. The change in the primary outcome measure scores from baseline was similar between the two groups. Motivated group veterans had a lower all-cause mortality rate at 12 months than less motivated veterans (P=0.001).

Conclusions: A higher level of motivation irrespective of the degree of depression did not improve cognitive or functional motor recovery scores. However, motivated veterans had a lower all-cause mortality at 12 months.

Clinical rehabilitation impact: The result of this study has important implications in clinical practice highlighting that motivated patients are more likely to be discharged home and have a lower all-cause mortality.

Background: The Achilles tendon is one of the most frequent sites of tendinopathy in both healthy and pathological subjects. An innovative approach for the quantitative assessment of the Achilles tendon structure, named Ultrasound Tissue Characterization (UTC), has recently been developed. However, no previous study performed the UTC-based assessment of the tendon structure in rheumatologic patients affected by insertional Achilles tendinopathy.

Aim: To characterize the Achilles tendon structure and function in psoriatic arthritis patients with symptomatic insertional tendinopathy.

Design: Cross-sectional study.

Setting: University laboratory.

Population: Psoriatic arthritis patients (N.=17).

Methods: Anthropometric measurements, administration of outcome and pain questionnaires, and tendon function and structure assessments were performed in a single experimental session.

Results: Pain intensity and interference and the perceived tendinopathy-related disability were moderate-severe. A relevant impairment of the strength (for both lower limbs) and walking performance was observed in all patients. In fact, the plantarflexion strength values (median values for the two sides: 10.0 and 11.5 kg) and fast walking speed (median value: 1.7 m/s) were lower than the normative values for healthy controls, respectively, in all patients for the strength values and in 14 out of 17 patients for the walking speed. The conventional ultrasound (i.e., the quantification of tendon thickness and the qualitative assessments of tendon structure and neovascularization) showed greater changes in the symptomatic (or more symptomatic) side compared with the asymptomatic (or less symptomatic) side of the insertional region of the Achilles tendon. The UTC imaging showed comparable impairment of the tendon structure between the symptomatic (or more symptomatic) side and the asymptomatic (or less symptomatic) side of the insertional region of the Achilles tendon (i.e., reduced echo-type I percentages in both tendons of all patients).

Conclusions: Psoriatic arthritis patients with symptomatic insertional Achilles tendinopathy present moderate-severe pain and perceived disability, physical function impairments, and bilateral deterioration of the tendon structure (also in case of unilateral symptoms) that can be documented through the UTC analysis.

Clinical rehabilitation impact: The evaluation of the insertional Achilles tendinopathy through UTC imaging can be useful for the diagnostic and prognostic assessment of psoriatic arthritis patients in combination with the assessments of pain, disability, and functional performance.

Background: Low back pain (LBP) accompanied by sciatica is a widespread musculoskeletal issue with multifactorial etiology, impacting individuals across various demographics. Conservative treatments, notably physiotherapy, are key in managing LBP with sciatica, with neural mobilization techniques emerging as beneficial adjuncts.

Aim: This research aims to assess the effectiveness of utilizing the sciatic slider technique (SST) in both supine and slump positions, compared to conventional physiotherapy alone, in alleviating pain severity, improving lumbar flexibility, lumbar lordosis, lower limb muscle strength, and functional ability in patients with LBP associated with sciatica.

Design: randomized controlled trial.

Setting: Department of Physiotherapy at Alia Hospital.

Population: Sixty participants with LBP associated with sciatica.

Methods: The participants were randomly allocated into three groups: Group (A) N.=20 received the SST in a slump position alongside conventional physiotherapy, Group (B) N.=20 received the same technique in a supine position with conventional physiotherapy, and Group (C) or (control) N.=20 underwent only conventional physiotherapy. Each group underwent three sessions per week for four weeks. Outcome measures included pain intensity (Numerical Pain Rating Scale), functional disability (Oswestry Disability Index), lumbar flexibility (Modified Schober test), lower limb muscle strength (Hand-held dynamometry), and lumbar lordosis (Flexible ruler).

Results: Analysis revealed significant differences between treatment groups. The slump position exhibited superior effectiveness in reducing pain intensity (P<0.001), and improving disability (P<0.001), with greater improvements in pain scores and disability index percentages. Additionally, slump position therapy led to significantly greater enhancements in range of motion (P<0.001), and hip abductor (P=0.007) when compared to the supine position. However, both techniques showed similar effects on lumbar lordosis angle and various lower limb muscle strength.

Conclusions: The sciatic nerve slider technique, whether applied in the slump or supine position, demonstrated superior outcomes compared to conventional physiotherapy alone in managing LBP with sciatica. Nevertheless, the slump position showed greater efficacy in reducing pain, improving disability, and enhancing certain functional parameters.

Clinical rehabilitation impact: These findings advocate for the inclusion of neural mobilization techniques, particularly in the slump position, in the management of LBP with sciatica.

Introduction: Latest epidemiological metrics put a global prevalence of 20.6 million people suffering from spinal cord injury (SCI), leading to a burden of functional disability, deterioration in quality of life and reduced life expectancy. A thorough statement of diagnostic methods and treatment protocols for swallowing disorders after SCI stands as a major priority to streamline patient care and cost-sharing. Here we have provided a systematic overview of the evidence on diagnostic and rehabilitation protocols of dysphagia in the SCI population.

Evidence acquisition: The literature was searched in six electronic databases up to April 30^th, 2024. Screening the 521 retrieved articles for inclusion criteria resulted in the selection of 43 studies that reported assessment tools and rehabilitation protocols for dysphagia in patients with SCI. Two researchers extracted the data in parallel, and inter-rater reliability (IRR) was used to estimate inter-coder agreement and then κ statistic to measure accuracy and precision. Based on PRISMA concepts and quality assessment steps, a k coefficient of at least 0.9 was obtained in all data extraction steps. All reports were assessed for risk of bias using the NIH Quality Assessment Toolkit. The study protocol was registered on PROSPERO (CRD42023449137).

Evidence synthesis: Dysphagia assessment methods were collected and grouped into four different macro categories (clinical assessment, rating scale, self-reported questionnaire, and instrumental assessment). It was found that the Bedside Swallow Evaluation (BSE) for the clinical assessment category (50%), the Bazaz score (32.5%) for the rating scale category, the Eating Assessment Tool-10 (EAT-10) (44.4%) for the self-reported questionnaire category, and the Videofluoroscopic Study of Swallowing (VFSS) (48.9%) for the instrumental assessment category were the most representative tools. The rehabilitation protocols described included either an early oral feeding exclusion or a consistency-modified oral intake, postural adaptations, oxygen therapy with a high-flow nasal cannula combined with indirect/direct therapy, specific exercises, and neuromuscular electrical stimulation.

Conclusions: Methods of diagnosis and rehabilitation protocols for dysphagia in SCI patients appear inconsistent. Further rigorous studies are needed to achieve better clinical handling in SCI settings while lowering the load of patient morbidity and related healthcare costs.

The need for medical rehabilitation is growing rapidly, including functional assessment and rehabilitation management of outpatients. The wide diversity of the out of the hospital PRM programs leads to define the basic principles and the role of the PRM specialist in the field. The aim of this article is to outline the core professional principles of the PRM for outpatient care, according to the Physical and Rehabilitation Medicine Section of the European Union of Medical Specialists. A Working Group (WG) on "Physical and Rehabilitation Medicine for Outpatients" was formed in March 2023. The final version was unanimously approved at the General Assembly on September 13^th, 2024. The principal aspects of PRM management of outpatients, according to the UEMS PRM Section, are reported. It is essential that PRM programs for outpatients are planned, developed, and implemented according to the professional principles of Physical and Rehabilitation Medicine in appropriate settings. They must be conducted by a multiprofessional team led by a PRM physician. These efforts aim to maximize functional outcomes and enhance the quality of life for individuals at risk of disability and chronic conditions.