首页 > 最新文献

European journal of physical and rehabilitation medicine最新文献

英文 中文
Correlation study between lower limb muscle function and hemodynamics in hemiplegic patients after stroke: a prospective controlled study. 卒中后偏瘫患者下肢肌肉功能与血流动力学的相关性研究:一项前瞻性对照研究。
IF 3.4 3区 医学 Q1 REHABILITATION Pub Date : 2025-08-01 DOI: 10.23736/S1973-9087.25.09102-6
Meiling Cheng, Wenjing Wang, Yang Yu, Tao Liu, Zebin Huang, Honghui Lei, Sitong Su, Haoyuan Chen, Fangyong Wang

Background: Stroke is a highly prevalent and disabling acute cerebrovascular disease. Existing assessment methods for hemiplegic patients have subjectivity, and research on combining surface electromyography and color Doppler ultrasound (CDUS) to evaluate lower limbs of stroke patients is scarce.

Aim: The study explored the correlation between quadriceps femoris muscle function and femoral artery hemodynamic parameters in hemiplegic patients after stroke for more accurate rehabilitation assessment.

Design: A prospective control study.

Setting: Hospital in-patient population.

Population: The sample comprised 20 post-stroke hemiplegic patients aged 18 - 80 years who met specific inclusion and exclusion criteria. Then the healthy side and the affected side were compared respectively.

Methods: The study chose surface electromyography and color Doppler ultrasound. Femoral artery hemodynamic parameters and quadriceps femoris electromyographic signals were detected before and after maximum isometric contraction. Differences between the affected and healthy sides and correlations were analyzed.

Results: The affected side had lower peak systolic velocity, arterial diameter, and surface electromyography indicators of the quadriceps femoris (except for increased end-diastolic velocity) (P<0.05). Significant differences were found in mean power frequency and median frequency of vastus medialis and vastus lateralis muscles (P<0.05). A positive correlation was found between the healthy side's quadriceps femoris median frequency and arterial diameter during contraction (r=0.489, P<0.05).

Conclusions: Lower limb muscle function impairment in hemiplegic patients after stroke is closely related to hemodynamic abnormalities. Combining surface electromyography and CDUS provides comprehensive rehabilitation assessment.

Clinical rehabilitation impact: This combined method can reduce subjective bias of traditional assessment, improve early assessment accuracy, and provide more precise references for stroke rehabilitation assessment and treatment.

背景:脑卒中是一种高发、致残的急性脑血管疾病。现有的偏瘫患者评估方法具有主观性,结合表面肌电图和彩色多普勒超声(CDUS)对脑卒中患者下肢进行评估的研究较少。目的:探讨脑卒中后偏瘫患者股四头肌功能与股动脉血流动力学参数的相关性,为更准确的康复评估提供依据。设计:前瞻性对照研究。研究对象:医院住院病人。人群:样本包括20例中风后偏瘫患者,年龄18 - 80岁,符合特定的纳入和排除标准。然后分别对健康侧和患侧进行比较。方法:采用体表肌电图和彩色多普勒超声。在最大等长收缩前后检测股动脉血流动力学参数和股四头肌肌电信号。分析患病侧与健康侧的差异及相关性。结果:患侧收缩峰值速度、动脉内径、股四头肌表面肌电指标均较低(舒张末速度升高除外)(p)。结论:卒中后偏瘫患者下肢肌肉功能损害与血流动力学异常密切相关。结合表面肌电图和CDUS提供全面的康复评估。临床康复影响:该组合方法可以减少传统评估的主观偏差,提高早期评估的准确性,为脑卒中康复评估和治疗提供更精确的参考。
{"title":"Correlation study between lower limb muscle function and hemodynamics in hemiplegic patients after stroke: a prospective controlled study.","authors":"Meiling Cheng, Wenjing Wang, Yang Yu, Tao Liu, Zebin Huang, Honghui Lei, Sitong Su, Haoyuan Chen, Fangyong Wang","doi":"10.23736/S1973-9087.25.09102-6","DOIUrl":"10.23736/S1973-9087.25.09102-6","url":null,"abstract":"<p><strong>Background: </strong>Stroke is a highly prevalent and disabling acute cerebrovascular disease. Existing assessment methods for hemiplegic patients have subjectivity, and research on combining surface electromyography and color Doppler ultrasound (CDUS) to evaluate lower limbs of stroke patients is scarce.</p><p><strong>Aim: </strong>The study explored the correlation between quadriceps femoris muscle function and femoral artery hemodynamic parameters in hemiplegic patients after stroke for more accurate rehabilitation assessment.</p><p><strong>Design: </strong>A prospective control study.</p><p><strong>Setting: </strong>Hospital in-patient population.</p><p><strong>Population: </strong>The sample comprised 20 post-stroke hemiplegic patients aged 18 - 80 years who met specific inclusion and exclusion criteria. Then the healthy side and the affected side were compared respectively.</p><p><strong>Methods: </strong>The study chose surface electromyography and color Doppler ultrasound. Femoral artery hemodynamic parameters and quadriceps femoris electromyographic signals were detected before and after maximum isometric contraction. Differences between the affected and healthy sides and correlations were analyzed.</p><p><strong>Results: </strong>The affected side had lower peak systolic velocity, arterial diameter, and surface electromyography indicators of the quadriceps femoris (except for increased end-diastolic velocity) (P<0.05). Significant differences were found in mean power frequency and median frequency of vastus medialis and vastus lateralis muscles (P<0.05). A positive correlation was found between the healthy side's quadriceps femoris median frequency and arterial diameter during contraction (r=0.489, P<0.05).</p><p><strong>Conclusions: </strong>Lower limb muscle function impairment in hemiplegic patients after stroke is closely related to hemodynamic abnormalities. Combining surface electromyography and CDUS provides comprehensive rehabilitation assessment.</p><p><strong>Clinical rehabilitation impact: </strong>This combined method can reduce subjective bias of traditional assessment, improve early assessment accuracy, and provide more precise references for stroke rehabilitation assessment and treatment.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":"61 4","pages":"595-607"},"PeriodicalIF":3.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12648277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145388226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of positive expiratory pressure buddy during exercise on chronic obstructive pulmonary disease patients' functional performance, lung function, and sleep quality: a randomized controlled trial. 运动时呼气正压对慢性阻塞性肺疾病患者功能表现、肺功能和睡眠质量的影响:一项随机对照试验
IF 3.4 3区 医学 Q1 REHABILITATION Pub Date : 2025-08-01 DOI: 10.23736/S1973-9087.25.08876-8
Mushabbab A Alahmari, Marwa M Elsayed, Hany F Elsisi, Ebtesam N Nagy

Background: Chronic obstructive lung disease is diverse and complex, exhibiting pulmonary and systematic symptoms that interrupt the patients' daily activities and sleep. The most frequent source of these symptoms is air stacking, which can be lessened by positive expiratory pressure Buddy, a simple and affordable device.

Aim: This study aimed to assess the impact of positive expiratory pressure Buddy during exercise on pulmonary function, functional performance, and sleep quality among those patients.

Design: Randomized controlled study.

Settings: Faculty of Physical Therapy, Cairo University, Outpatient Clinic.

Population: Sixty patients with moderate-to-severe chronic obstructive lung disease, aged 55 to 65.

Methods: The participants were allocated evenly into two groups: the experimental group, which used the positive expiratory pressure Buddy while doing the aerobic exercise, and the control group, which did the same aerobic training without using the PEP Buddy. Spirometry (forced expiratory volume in 1 second and forced expiratory volume in 1 second/forced vital capacity ratio), dyspnea, a six-minute walk test distance, sleep quality, and quality of life (St. George Respiratory Questionnaire) were used to evaluate the patients both before and after the study's eight-week timeframe.

Results: The experimental group showed higher significant improvements in all assessed parameters than the control group after eight weeks of intervention (P<0.001).

Conclusions: When combined with a regular exercise regimen, positive expiratory pressure Buddy is an extremely adherence intervention that improves sleep, exercise capacity, pulmonary function, and general quality of life. Thus, it can be considered an excellent choice for patients receiving at-home treatment.

Clinical rehabilitation impact: Chronic obstructive pulmonary disease is a major global health issue that affects society, healthcare systems, and patients' health and quality of life. Its management is still challenging, necessitating the use of alternative therapy approaches.

背景:慢性阻塞性肺疾病多样而复杂,表现出肺部和全身症状,干扰患者的日常活动和睡眠。这些症状最常见的来源是空气堆积,这可以通过呼气正压Buddy(一种简单且负担得起的设备)来减轻。目的:本研究旨在评估运动时呼气正压对患者肺功能、功能表现和睡眠质量的影响。设计:随机对照研究。环境:开罗大学物理治疗学院,门诊。人群:60例患有中重度慢性阻塞性肺疾病的患者,年龄55 - 65岁。方法:将参与者平均分为两组:实验组在进行有氧运动时使用呼气正压Buddy,对照组在进行相同的有氧训练时不使用PEP Buddy。使用肺活量测定法(1秒用力呼气量和1秒用力呼气量/用力肺活量比)、呼吸困难、6分钟步行测试距离、睡眠质量和生活质量(St. George呼吸问卷)评估患者在研究8周时间框架前后的情况。结果:经过8周的干预,实验组在所有评估参数上都比对照组有更高的显著改善(结论:当与常规运动方案相结合时,呼气正压Buddy是一种非常坚持的干预,可以改善睡眠、运动能力、肺功能和总体生活质量。因此,它可以被认为是接受家庭治疗的患者的一个很好的选择。临床康复影响:慢性阻塞性肺疾病是影响社会、卫生保健系统以及患者健康和生活质量的主要全球健康问题。其管理仍然具有挑战性,需要使用替代治疗方法。
{"title":"Impact of positive expiratory pressure buddy during exercise on chronic obstructive pulmonary disease patients' functional performance, lung function, and sleep quality: a randomized controlled trial.","authors":"Mushabbab A Alahmari, Marwa M Elsayed, Hany F Elsisi, Ebtesam N Nagy","doi":"10.23736/S1973-9087.25.08876-8","DOIUrl":"10.23736/S1973-9087.25.08876-8","url":null,"abstract":"<p><strong>Background: </strong>Chronic obstructive lung disease is diverse and complex, exhibiting pulmonary and systematic symptoms that interrupt the patients' daily activities and sleep. The most frequent source of these symptoms is air stacking, which can be lessened by positive expiratory pressure Buddy, a simple and affordable device.</p><p><strong>Aim: </strong>This study aimed to assess the impact of positive expiratory pressure Buddy during exercise on pulmonary function, functional performance, and sleep quality among those patients.</p><p><strong>Design: </strong>Randomized controlled study.</p><p><strong>Settings: </strong>Faculty of Physical Therapy, Cairo University, Outpatient Clinic.</p><p><strong>Population: </strong>Sixty patients with moderate-to-severe chronic obstructive lung disease, aged 55 to 65.</p><p><strong>Methods: </strong>The participants were allocated evenly into two groups: the experimental group, which used the positive expiratory pressure Buddy while doing the aerobic exercise, and the control group, which did the same aerobic training without using the PEP Buddy. Spirometry (forced expiratory volume in 1 second and forced expiratory volume in 1 second/forced vital capacity ratio), dyspnea, a six-minute walk test distance, sleep quality, and quality of life (St. George Respiratory Questionnaire) were used to evaluate the patients both before and after the study's eight-week timeframe.</p><p><strong>Results: </strong>The experimental group showed higher significant improvements in all assessed parameters than the control group after eight weeks of intervention (P<0.001).</p><p><strong>Conclusions: </strong>When combined with a regular exercise regimen, positive expiratory pressure Buddy is an extremely adherence intervention that improves sleep, exercise capacity, pulmonary function, and general quality of life. Thus, it can be considered an excellent choice for patients receiving at-home treatment.</p><p><strong>Clinical rehabilitation impact: </strong>Chronic obstructive pulmonary disease is a major global health issue that affects society, healthcare systems, and patients' health and quality of life. Its management is still challenging, necessitating the use of alternative therapy approaches.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":"61 4","pages":"669-678"},"PeriodicalIF":3.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12648278/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145388284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The impact of inpatient and community stroke rehabilitation on health-related quality of life in New Zealand. 住院和社区中风康复对新西兰健康相关生活质量的影响
IF 3.4 3区 医学 Q1 REHABILITATION Pub Date : 2025-08-01 DOI: 10.23736/S1973-9087.25.08903-8
Stephanie G Thompson, Dhairya Thakkar, Harry McNaughton, William Levack, Anna Ranta

Background: Stroke rehabilitation - both inpatient and community - is an important part of current post-stroke care, aimed at improving outcomes. However, there is a lack of recent New Zealand research exploring associations between rehabilitation and health-related quality of life (HRQoL) post stroke.

Aim: To explore associations between stroke rehabilitation and HRQoL.

Design: Secondary analysis of data from a prospective, observational study.

Setting: Twenty-eight New Zealand hospitals.

Population: Overall, 2379 patients with stroke.

Methods: Data was collected from consecutive patients with stroke who were admitted to New Zealand hospitals between 1st May and 31st July 2018. Further data collection occurred until the target sample size was reached, or until 31st October 2018, whichever occurred first. Patients were contacted for routine follow-up at three months and were invited to consent to follow-up at six and 12 months. We used the EQ-5D-3L and calculated the health utility score using weightings for the New Zealand population. We used linear regression to explore correlations between rehabilitation and HRQOL, adjusting for known confounders including stroke severity.

Results: There were 750/2379 (31.5%) patients who received inpatient rehabilitation and 838/2379 (35.2%) who received community rehabilitation. In a multivariate analysis, patients who received inpatient rehabilitation, compared to people who did not, had lower HRQoL scores at both three months (-0.07, 95% CI -0.10 to -0.04) and 12 months (-0.08, 95% CI -0.12 to -0.04). Patients who received community rehabilitation had higher HRQoL scores at 12 months (0.04, 95% CI 0.002 to 0.08)). Stratifying scores by stroke severity, we found results in favor of inpatient rehabilitation for only the most severely impaired patients and for community rehabilitation for all but the least impaired.

Conclusions: We found a negative correlation between HRQoL and inpatient rehabilitation, and a positive association between HRQoL and community rehabilitation. A combination of personal, environmental and service factors may explain this result. Future research directly comparing outcomes for patients receiving comprehensive community-based and inpatient rehabilitation, would be useful to support stroke rehabilitation service development.

Clinical rehabilitation impact: Individualized rehabilitation planning should consider social supports, the home environment, functional level and patient preference to support decision-making around rehabilitation location and optimize outcomes.

背景:卒中康复-住院和社区-是当前卒中后护理的重要组成部分,旨在改善预后。然而,最近新西兰缺乏关于卒中后康复与健康相关生活质量(HRQoL)之间关系的研究。目的:探讨脑卒中康复与HRQoL的关系。设计:对前瞻性观察性研究数据进行二次分析。地点:新西兰28家医院。人群:2379例卒中患者。方法:收集2018年5月1日至7月31日在新西兰医院住院的连续脑卒中患者的数据。在达到目标样本量之前,或在2018年10月31日之前进行进一步的数据收集,以先发生者为准。在3个月时与患者进行常规随访,并在6个月和12个月时邀请患者同意随访。我们使用EQ-5D-3L,并使用新西兰人口的权重计算健康效用得分。我们使用线性回归来探讨康复与HRQOL之间的相关性,调整已知混杂因素,包括中风严重程度。结果:接受住院康复的750/2379例(31.5%),接受社区康复的838/2379例(35.2%)。在一项多变量分析中,与未接受住院康复的患者相比,接受住院康复的患者在三个月(-0.07,95% CI -0.10至-0.04)和12个月(-0.08,95% CI -0.12至-0.04)的HRQoL评分均较低。接受社区康复的患者在12个月时HRQoL评分较高(0.04,95% CI 0.002 ~ 0.08)。根据中风严重程度对评分进行分层,我们发现只有受损最严重的患者才需要住院康复,而除了受损最轻的患者外,所有患者都需要社区康复。结论:患者HRQoL与住院康复呈负相关,与社区康复呈正相关。个人因素、环境因素和服务因素综合起来可以解释这一结果。未来的研究直接比较社区综合康复和住院康复患者的结果,将有助于支持脑卒中康复服务的发展。临床康复影响:个性化康复规划应考虑社会支持、家庭环境、功能水平和患者偏好,以支持围绕康复地点的决策并优化结果。
{"title":"The impact of inpatient and community stroke rehabilitation on health-related quality of life in New Zealand.","authors":"Stephanie G Thompson, Dhairya Thakkar, Harry McNaughton, William Levack, Anna Ranta","doi":"10.23736/S1973-9087.25.08903-8","DOIUrl":"10.23736/S1973-9087.25.08903-8","url":null,"abstract":"<p><strong>Background: </strong>Stroke rehabilitation - both inpatient and community - is an important part of current post-stroke care, aimed at improving outcomes. However, there is a lack of recent New Zealand research exploring associations between rehabilitation and health-related quality of life (HRQoL) post stroke.</p><p><strong>Aim: </strong>To explore associations between stroke rehabilitation and HRQoL.</p><p><strong>Design: </strong>Secondary analysis of data from a prospective, observational study.</p><p><strong>Setting: </strong>Twenty-eight New Zealand hospitals.</p><p><strong>Population: </strong>Overall, 2379 patients with stroke.</p><p><strong>Methods: </strong>Data was collected from consecutive patients with stroke who were admitted to New Zealand hospitals between 1<sup>st</sup> May and 31<sup>st</sup> July 2018. Further data collection occurred until the target sample size was reached, or until 31<sup>st</sup> October 2018, whichever occurred first. Patients were contacted for routine follow-up at three months and were invited to consent to follow-up at six and 12 months. We used the EQ-5D-3L and calculated the health utility score using weightings for the New Zealand population. We used linear regression to explore correlations between rehabilitation and HRQOL, adjusting for known confounders including stroke severity.</p><p><strong>Results: </strong>There were 750/2379 (31.5%) patients who received inpatient rehabilitation and 838/2379 (35.2%) who received community rehabilitation. In a multivariate analysis, patients who received inpatient rehabilitation, compared to people who did not, had lower HRQoL scores at both three months (-0.07, 95% CI -0.10 to -0.04) and 12 months (-0.08, 95% CI -0.12 to -0.04). Patients who received community rehabilitation had higher HRQoL scores at 12 months (0.04, 95% CI 0.002 to 0.08)). Stratifying scores by stroke severity, we found results in favor of inpatient rehabilitation for only the most severely impaired patients and for community rehabilitation for all but the least impaired.</p><p><strong>Conclusions: </strong>We found a negative correlation between HRQoL and inpatient rehabilitation, and a positive association between HRQoL and community rehabilitation. A combination of personal, environmental and service factors may explain this result. Future research directly comparing outcomes for patients receiving comprehensive community-based and inpatient rehabilitation, would be useful to support stroke rehabilitation service development.</p><p><strong>Clinical rehabilitation impact: </strong>Individualized rehabilitation planning should consider social supports, the home environment, functional level and patient preference to support decision-making around rehabilitation location and optimize outcomes.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":"61 4","pages":"587-594"},"PeriodicalIF":3.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12613447/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145388313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Combining low-frequency magnetic stimulation with motor imagery to improve lower limb recovery and motor pathway integrity in cerebral infarction: a randomized, double-blind, and controlled study. 结合低频磁刺激与运动想象改善脑梗死患者下肢恢复和运动通路完整性:一项随机、双盲和对照研究
IF 3.4 3区 医学 Q1 REHABILITATION Pub Date : 2025-08-01 DOI: 10.23736/S1973-9087.25.08945-2
Jiasheng Wang, Yang Ye, Xuehan Zang, Jing Yang, Juan Fu, Qiwei Li, Hong Hong, Zhimin Huang, Xianwei Che, Lingyan Wang, Aiqun Shi

Background: Lower limb dysfunction is common after stroke. While physical rehabilitation is the most widely used treatment, its effectiveness is limited in improving motor function.

Aim: This study aimed to investigate the effect of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) combined with motor imagery (MI) on lower limb motor dysfunction in cerebral infarction patients.

Design: A randomized, double-blind, and controlled study.

Setting: The Rehabilitation Department of a single Hospital.

Population: Sixty patients with lower limb motor impairment post-cerebral infarction were randomly allocated to the rTMS group, the MI group, and the combined rTMS + MI group.

Methods: All groups received standard physical rehabilitation training and the allocated treatment for 3 weeks. Motor function was evaluated before and after intervention with the Fugl-Meyer Lower Extremity Motor Function Scale (FMA-LE), Holden Walking Functional Classification (FAC), and Time-Up-Go Time Test (TUGT). Magnetic resonance diffusion tensor imaging (DTI) was used to assess fractional anisotropy (FA) and the bilateral FA ratios (rFA) in the corona radiata, cerebral peduncles, posterior limb of the internal capsule, and infarction foci.

Results: The combined treatment increased lower limb motor function (FMA-LE), walking ability (FAC levels), and functional mobility of the lower limb (TUGT), compared to patients receiving MI therapy alone. The combined treatment also had a superior effect to rTMS alone on walking ability. Furthermore, DTI findings demonstrated a more prominent increase in FA and rFA, mainly in the corona radiata, posterior limb of the internal capsule, and the infarcted foci following the combined treatment.

Conclusions: LF-rTMS combined with MI could significantly enhance lower limb motor function in cerebral infarction patients, potentially by promoting neuroplasticity and functional connectivity along the motor pathways. Due to a lack of control group, much of the observed recovery was likely due to spontaneous improvement, given that our patients were in the sub-acute phase of stroke with mild to moderate motor impairment.

Clinical rehabilitation impact: This novel therapy provides a promising approach for improving lower limb motor recovery in stroke rehabilitation.

背景:卒中后下肢功能障碍很常见。虽然物理康复是最广泛使用的治疗方法,但其在改善运动功能方面的效果有限。目的:探讨低频重复经颅磁刺激(LF-rTMS)联合运动想象(MI)对脑梗死患者下肢运动功能障碍的影响。设计:随机、双盲、对照研究。单位:某医院康复科。人群:60例脑梗死后下肢运动障碍患者随机分为rTMS组、MI组和rTMS + MI联合组。方法:各组均接受标准的肢体康复训练,并进行3周的分组治疗。采用Fugl-Meyer下肢运动功能量表(FMA-LE)、Holden步行功能分类(FAC)和Time- up - go Time Test (TUGT)评估干预前后的运动功能。采用磁共振弥散张量成像(DTI)评估放射冠、脑梗、内囊后肢和梗死灶的分数各向异性(FA)和双侧FA比值(rFA)。结果:与单独接受心肌梗死治疗的患者相比,联合治疗增加了下肢运动功能(FMA-LE)、行走能力(FAC水平)和下肢功能活动度(TUGT)。联合治疗对行走能力的影响也优于单用rTMS。此外,DTI结果显示,联合治疗后,FA和rFA的增加更为显著,主要发生在放射冠、内囊后肢和梗死灶。结论:LF-rTMS联合心肌梗死可显著增强脑梗死患者的下肢运动功能,可能是通过促进运动通路的神经可塑性和功能连通性来实现的。由于缺乏对照组,考虑到我们的患者处于卒中亚急性期并伴有轻度至中度运动障碍,大部分观察到的恢复可能是由于自发改善。临床康复影响:这种新疗法为卒中康复中改善下肢运动恢复提供了一种有希望的方法。
{"title":"Combining low-frequency magnetic stimulation with motor imagery to improve lower limb recovery and motor pathway integrity in cerebral infarction: a randomized, double-blind, and controlled study.","authors":"Jiasheng Wang, Yang Ye, Xuehan Zang, Jing Yang, Juan Fu, Qiwei Li, Hong Hong, Zhimin Huang, Xianwei Che, Lingyan Wang, Aiqun Shi","doi":"10.23736/S1973-9087.25.08945-2","DOIUrl":"10.23736/S1973-9087.25.08945-2","url":null,"abstract":"<p><strong>Background: </strong>Lower limb dysfunction is common after stroke. While physical rehabilitation is the most widely used treatment, its effectiveness is limited in improving motor function.</p><p><strong>Aim: </strong>This study aimed to investigate the effect of low-frequency repetitive transcranial magnetic stimulation (LF-rTMS) combined with motor imagery (MI) on lower limb motor dysfunction in cerebral infarction patients.</p><p><strong>Design: </strong>A randomized, double-blind, and controlled study.</p><p><strong>Setting: </strong>The Rehabilitation Department of a single Hospital.</p><p><strong>Population: </strong>Sixty patients with lower limb motor impairment post-cerebral infarction were randomly allocated to the rTMS group, the MI group, and the combined rTMS + MI group.</p><p><strong>Methods: </strong>All groups received standard physical rehabilitation training and the allocated treatment for 3 weeks. Motor function was evaluated before and after intervention with the Fugl-Meyer Lower Extremity Motor Function Scale (FMA-LE), Holden Walking Functional Classification (FAC), and Time-Up-Go Time Test (TUGT). Magnetic resonance diffusion tensor imaging (DTI) was used to assess fractional anisotropy (FA) and the bilateral FA ratios (rFA) in the corona radiata, cerebral peduncles, posterior limb of the internal capsule, and infarction foci.</p><p><strong>Results: </strong>The combined treatment increased lower limb motor function (FMA-LE), walking ability (FAC levels), and functional mobility of the lower limb (TUGT), compared to patients receiving MI therapy alone. The combined treatment also had a superior effect to rTMS alone on walking ability. Furthermore, DTI findings demonstrated a more prominent increase in FA and rFA, mainly in the corona radiata, posterior limb of the internal capsule, and the infarcted foci following the combined treatment.</p><p><strong>Conclusions: </strong>LF-rTMS combined with MI could significantly enhance lower limb motor function in cerebral infarction patients, potentially by promoting neuroplasticity and functional connectivity along the motor pathways. Due to a lack of control group, much of the observed recovery was likely due to spontaneous improvement, given that our patients were in the sub-acute phase of stroke with mild to moderate motor impairment.</p><p><strong>Clinical rehabilitation impact: </strong>This novel therapy provides a promising approach for improving lower limb motor recovery in stroke rehabilitation.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":"61 4","pages":"608-619"},"PeriodicalIF":3.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12699277/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145388188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retraction of: "What can I do for my low back pain? The Work In Progress questionnaire!" 收回:“我的腰痛该怎么做?”正在进行的工作问卷!”
IF 3.4 3区 医学 Q1 REHABILITATION Pub Date : 2025-08-01 DOI: 10.23736/S1973-9087.25.09263-9
Marco Monticone, Federico Arippa, Roberto Garri, Andrea Pibiri, Maicol Formentelli, Barbara Rocca

This article has been retracted by agreement between the authors, Editors and Publisher. The author responsible for managing the ethics committee's approval (B.R.) acknowledges full responsibility for the absence of the requested contact information for the local ethics committee, which was also not included in the official approval documentation. The other authors were not involved in this aspect and bear no responsibility for this omission.

经作者、编辑和出版商同意,这篇文章已被撤回。负责管理伦理委员会批准(B.R.)的作者承认对缺少当地伦理委员会的联系信息负全部责任,官方批准文件中也没有包括这些联系信息。其他作者没有参与这方面的工作,对这一疏忽不负任何责任。
{"title":"Retraction of: \"What can I do for my low back pain? The Work In Progress questionnaire!\"","authors":"Marco Monticone, Federico Arippa, Roberto Garri, Andrea Pibiri, Maicol Formentelli, Barbara Rocca","doi":"10.23736/S1973-9087.25.09263-9","DOIUrl":"10.23736/S1973-9087.25.09263-9","url":null,"abstract":"<p><p>This article has been retracted by agreement between the authors, Editors and Publisher. The author responsible for managing the ethics committee's approval (B.R.) acknowledges full responsibility for the absence of the requested contact information for the local ethics committee, which was also not included in the official approval documentation. The other authors were not involved in this aspect and bear no responsibility for this omission.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":"61 4","pages":"689"},"PeriodicalIF":3.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12623121/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145388266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of telehealth pelvic-abdominal mechanics training rehabilitation program for pelvic floor rehabilitation in puerperal women: a randomized controlled study. 远程保健骨盆-腹部力学训练康复计划对产褥期妇女盆底康复的有效性:一项随机对照研究。
IF 3.4 3区 医学 Q1 REHABILITATION Pub Date : 2025-08-01 Epub Date: 2025-09-19 DOI: 10.23736/S1973-9087.25.08971-3
Ran Zhang, Yu Guo, Jiahua Zhang, Jing Zhang, Rui Zhuang, Chunli Liao, Haixin Bo
<p><strong>Background: </strong>There are still numerous barriers to the implementation of pelvic floor muscle training (PFMT), though it has been the first-line treatment for pelvic floor dysfunction (PFD) in puerperal women. The construction of telehealth pelvic floor rehabilitation program that is both fun and accessible is necessary.</p><p><strong>Aim: </strong>To assess the efficacy of telehealth pelvic-abdominal mechanics rehabilitation training program for pelvic floor rehabilitation in puerperal women.</p><p><strong>Design: </strong>A randomized controlled trial.</p><p><strong>Setting: </strong>Home-based exercise program.</p><p><strong>Population: </strong>Singleton, cephalic primiparous women.</p><p><strong>Methods: </strong>The 60 participants recruited were randomly assigned to either the intervention or control group. The intervention group received a telehealth pelvic-abdominal mechanics training rehabilitation program for 6 weeks, while the control group remained on the routine care. The degree of distress of PFD in puerperal women was assessed at one week postpartum (T1) and 42 days postpartum (T2). The level of knowledge, attitudes and self-efficacy towards PFMT were assessed at 2 days postpartum (T0), T1and T2. The degree of inter-recti distance (IRD) was assessed at T0 and T2. Pelvic floor muscle strength was assessed at T2, including modified Oxford muscle strength (MOS) classification and dynamic maximal vaginal pressure values. Statistical analysis methods were chosen based on the type of statistical data, mainly including t-test and two-factor repeated measures ANOVA.</p><p><strong>Results: </strong>No adverse outcomes occurred in all participants. After a 6-week intervention, the intervention group had a significantly lower PFDI-20 score than the control group at T2 and exhibited a lesser degree of IRD. At T1 and T2, the simple effect of group was significant, with the intervention group demonstrating higher levels of knowledge and attitude towards PFMT compared to the control group (F=4.427, P=0.040, partial η<sup>2</sup>=0.071; F=5.266, P=0.025, partial η<sup>2</sup>=0.083). At T2, the simple effect of group was significant, with the intervention group demonstrating higher level of self-efficacy towards PFMT compared to the control group (F=37.908, P<0.001, partial η<sup>2</sup>=0.395). There was no statistically significant difference between the two groups in terms of Oxford muscle strength classification, dynamic maximal vaginal pressure values, muscle fiber strength of type I and type II at T2.</p><p><strong>Conclusions: </strong>This study provided evidence that telehealth pelvic-abdominal mechanics training rehabilitation program can significantly improve the rehabilitation effect of puerperal women.</p><p><strong>Clinical rehabilitation impact: </strong>A pelvic-abdominal mechanics training rehabilitation program during the puerperium is safe and effective. Telemedicine is an extremely recommended means of pelvic
背景:尽管盆底肌训练(PFMT)已成为产褥期妇女盆底功能障碍(PFD)的一线治疗方法,但其实施仍存在许多障碍。建立一个既有趣又方便的远程医疗盆底康复项目是必要的。目的:评价远程保健盆腹力学康复训练方案对产褥期妇女盆底康复的效果。设计:随机对照试验。设置:基于家庭的锻炼计划。人群:单胎,头侧初产妇。方法:将60名参与者随机分为干预组和对照组。干预组采用远程保健盆腹力学训练康复方案,为期6周,对照组维持常规护理。在产后1周(T1)和产后42天(T2)评估产褥期妇女PFD的痛苦程度。分别于产后2 d (T0)、t1、T2评估产妇对PFMT的知识、态度和自我效能感水平。在T0和T2时评估直间距(IRD)程度。T2时评估盆底肌力,包括改良牛津肌力(MOS)分级和动态阴道最大压力值。根据统计资料的类型选择统计分析方法,主要包括t检验和双因素重复测量方差分析。结果:所有受试者均未发生不良结局。干预6周后,干预组在T2时PFDI-20评分明显低于对照组,IRD程度较轻。在T1和T2时,实验组的单纯效果显著,干预组对PFMT的认知和态度高于对照组(F=4.427, P=0.040,偏η2=0.071; F=5.266, P=0.025,偏η2=0.083)。T2时,干预组单纯效果显著,干预组对PFMT的自我效能水平高于对照组(F=37.908, P2=0.395)。两组在T2时的牛津肌力分级、阴道动态最大压力值、I型和II型肌纤维强度比较,差异均无统计学意义。结论:远程保健盆腹力学训练康复方案可显著提高产褥期妇女的康复效果。临床康复影响:产褥期盆腹力学训练康复方案安全有效。远程医疗是一种非常推荐的手段盆底康复产褥期。
{"title":"Effectiveness of telehealth pelvic-abdominal mechanics training rehabilitation program for pelvic floor rehabilitation in puerperal women: a randomized controlled study.","authors":"Ran Zhang, Yu Guo, Jiahua Zhang, Jing Zhang, Rui Zhuang, Chunli Liao, Haixin Bo","doi":"10.23736/S1973-9087.25.08971-3","DOIUrl":"10.23736/S1973-9087.25.08971-3","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;There are still numerous barriers to the implementation of pelvic floor muscle training (PFMT), though it has been the first-line treatment for pelvic floor dysfunction (PFD) in puerperal women. The construction of telehealth pelvic floor rehabilitation program that is both fun and accessible is necessary.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To assess the efficacy of telehealth pelvic-abdominal mechanics rehabilitation training program for pelvic floor rehabilitation in puerperal women.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Design: &lt;/strong&gt;A randomized controlled trial.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Setting: &lt;/strong&gt;Home-based exercise program.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Population: &lt;/strong&gt;Singleton, cephalic primiparous women.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The 60 participants recruited were randomly assigned to either the intervention or control group. The intervention group received a telehealth pelvic-abdominal mechanics training rehabilitation program for 6 weeks, while the control group remained on the routine care. The degree of distress of PFD in puerperal women was assessed at one week postpartum (T1) and 42 days postpartum (T2). The level of knowledge, attitudes and self-efficacy towards PFMT were assessed at 2 days postpartum (T0), T1and T2. The degree of inter-recti distance (IRD) was assessed at T0 and T2. Pelvic floor muscle strength was assessed at T2, including modified Oxford muscle strength (MOS) classification and dynamic maximal vaginal pressure values. Statistical analysis methods were chosen based on the type of statistical data, mainly including t-test and two-factor repeated measures ANOVA.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;No adverse outcomes occurred in all participants. After a 6-week intervention, the intervention group had a significantly lower PFDI-20 score than the control group at T2 and exhibited a lesser degree of IRD. At T1 and T2, the simple effect of group was significant, with the intervention group demonstrating higher levels of knowledge and attitude towards PFMT compared to the control group (F=4.427, P=0.040, partial η&lt;sup&gt;2&lt;/sup&gt;=0.071; F=5.266, P=0.025, partial η&lt;sup&gt;2&lt;/sup&gt;=0.083). At T2, the simple effect of group was significant, with the intervention group demonstrating higher level of self-efficacy towards PFMT compared to the control group (F=37.908, P&lt;0.001, partial η&lt;sup&gt;2&lt;/sup&gt;=0.395). There was no statistically significant difference between the two groups in terms of Oxford muscle strength classification, dynamic maximal vaginal pressure values, muscle fiber strength of type I and type II at T2.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;This study provided evidence that telehealth pelvic-abdominal mechanics training rehabilitation program can significantly improve the rehabilitation effect of puerperal women.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical rehabilitation impact: &lt;/strong&gt;A pelvic-abdominal mechanics training rehabilitation program during the puerperium is safe and effective. Telemedicine is an extremely recommended means of pelvic ","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":" ","pages":"679-688"},"PeriodicalIF":3.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12613446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145085595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multi-wave locked system laser therapy in chronic non-specific neck pain: a double-blind placebo randomized-controlled trial. 多波锁定系统激光治疗慢性非特异性颈部疼痛:双盲安慰剂随机对照试验。
IF 3.4 3区 医学 Q1 REHABILITATION Pub Date : 2025-08-01 DOI: 10.23736/S1973-9087.25.08615-0
Luciana Labanca, Daniela Platano, Roberto Tedeschi, Elena Cappelli, Maria G Benedetti, Lisa Berti

Background: Multi-wave locked system (MLS) laser therapy has shown efficacy in reducing pain in various musculoskeletal conditions. However, its standalone effects on pain and function in patients with chronic non-specific neck pain (CNNP) remain unclear.

Aim: The aim of this study was to evaluate the effects of MLS laser therapy on pain, function, and disability in patients with CNNP compared to a placebo treatment.

Design: Randomized controlled study.

Setting: Outpatient.

Population: Patients aged 20-65 years with CNNP and a neck pain score between 4 and 7 on a Visual Analogue Scale.

Methods: Forty-seven patients were randomized into two groups: MLS Laser and Sham Laser, receiving 8 sessions of their respective treatments. Assessments were conducted at baseline (T0), end of therapy (T1), and one month post-therapy (T2) for neck pain (VAS), function (kinematics and electromyography of head movements), and disability (Neck Disability Index, NDI). Within- and between-group differences were analyzed across these time points.

Results: The MLS Laser group showed significant improvements (P<0.05) in the range of motion for head lateral bending and rotation compared to the Sham Laser group, which exhibited no changes. Both groups demonstrated increased movement velocity (P<0.05) and reduced pain and disability scores (P<0.05). However, either VAS and NDI did not reach the thresholds for minimal clinically important differences (MCID). At T2, a trend towards greater pain reduction was observed in the MLS Laser group (P=0.05).

Conclusions: Both MLS Laser and Sham Laser therapies resulted in statistically significant improvements in pain, disability, and movement velocity. However, these changes were not clinically meaningful. MLS Laser therapy provided more pronounced and sustained pain relief and improved range of motion in head movements.

Clinical rehabilitation impact: MLS Laser therapy improves neck range of motion as a standalone treatment for chronic non-specific neck pain, despite similar effects on pain and disability reduction with placebo.

背景:多波锁定系统(MLS)激光治疗已显示出减轻各种肌肉骨骼疾病疼痛的疗效。然而,其对慢性非特异性颈部疼痛(CNNP)患者疼痛和功能的单独影响尚不清楚。目的:本研究的目的是评估与安慰剂治疗相比,MLS激光治疗对CNNP患者疼痛、功能和残疾的影响。设计:随机对照研究。设置:门诊。人群:年龄在20-65岁的CNNP患者,颈部疼痛在视觉模拟量表上评分在4 - 7之间。方法:47例患者随机分为MLS激光组和Sham激光组,分别接受8个疗程的治疗。在基线(T0)、治疗结束(T1)和治疗后1个月(T2)对颈部疼痛(VAS)、功能(头部运动的运动学和肌电图)和残疾(颈部残疾指数,NDI)进行评估。在这些时间点上分析组内和组间差异。结论:MLS激光治疗和假激光治疗在疼痛、残疾和运动速度方面均有统计学意义的改善。然而,这些变化没有临床意义。MLS激光治疗提供更明显和持续的疼痛缓解和改善头部运动的运动范围。临床康复影响:MLS激光治疗可以改善颈部活动范围,作为慢性非特异性颈部疼痛的独立治疗,尽管安慰剂在减轻疼痛和残疾方面的效果相似。
{"title":"Multi-wave locked system laser therapy in chronic non-specific neck pain: a double-blind placebo randomized-controlled trial.","authors":"Luciana Labanca, Daniela Platano, Roberto Tedeschi, Elena Cappelli, Maria G Benedetti, Lisa Berti","doi":"10.23736/S1973-9087.25.08615-0","DOIUrl":"10.23736/S1973-9087.25.08615-0","url":null,"abstract":"<p><strong>Background: </strong>Multi-wave locked system (MLS) laser therapy has shown efficacy in reducing pain in various musculoskeletal conditions. However, its standalone effects on pain and function in patients with chronic non-specific neck pain (CNNP) remain unclear.</p><p><strong>Aim: </strong>The aim of this study was to evaluate the effects of MLS laser therapy on pain, function, and disability in patients with CNNP compared to a placebo treatment.</p><p><strong>Design: </strong>Randomized controlled study.</p><p><strong>Setting: </strong>Outpatient.</p><p><strong>Population: </strong>Patients aged 20-65 years with CNNP and a neck pain score between 4 and 7 on a Visual Analogue Scale.</p><p><strong>Methods: </strong>Forty-seven patients were randomized into two groups: MLS Laser and Sham Laser, receiving 8 sessions of their respective treatments. Assessments were conducted at baseline (T0), end of therapy (T1), and one month post-therapy (T2) for neck pain (VAS), function (kinematics and electromyography of head movements), and disability (Neck Disability Index, NDI). Within- and between-group differences were analyzed across these time points.</p><p><strong>Results: </strong>The MLS Laser group showed significant improvements (P<0.05) in the range of motion for head lateral bending and rotation compared to the Sham Laser group, which exhibited no changes. Both groups demonstrated increased movement velocity (P<0.05) and reduced pain and disability scores (P<0.05). However, either VAS and NDI did not reach the thresholds for minimal clinically important differences (MCID). At T2, a trend towards greater pain reduction was observed in the MLS Laser group (P=0.05).</p><p><strong>Conclusions: </strong>Both MLS Laser and Sham Laser therapies resulted in statistically significant improvements in pain, disability, and movement velocity. However, these changes were not clinically meaningful. MLS Laser therapy provided more pronounced and sustained pain relief and improved range of motion in head movements.</p><p><strong>Clinical rehabilitation impact: </strong>MLS Laser therapy improves neck range of motion as a standalone treatment for chronic non-specific neck pain, despite similar effects on pain and disability reduction with placebo.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":"61 4","pages":"645-654"},"PeriodicalIF":3.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12658590/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145388296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of home exercise programs in patients with non-tears rotator cuff-related shoulder pain: a systematic review and meta-analysis. 家庭运动项目对非撕裂性肩袖相关肩痛患者的影响:一项系统回顾和荟萃分析。
IF 3.4 3区 医学 Q1 REHABILITATION Pub Date : 2025-08-01 DOI: 10.23736/S1973-9087.25.08607-1
Sergio Hernández-Sánchez, José V Segura-Heras, Paula Andreu-Conde, Manuel Albornoz-Cabello, Luis Espejo-Antúnez, José V Toledo-Marhuenda

Introduction: Conservative treatment based on physiotherapy is the first option for non-tears rotator cuff related shoulder pain (RCSP). Although several studies demonstrate the positive effect of therapeutic exercise, aspects such as the influence of supervised exercises versus home-self training or the level of adherence are still unclear. The objective is to study the effect of home exercise programs compared to supervised exercise, either alone or combined with standard physiotherapy treatment.

Evidence acquisition: Web of Science, PubMed, SCOPUS, EMBASE, trials registries and reference lists with relevant articles were searched up to March 2025. Only randomized controlled trials were included that aimed to compare the effect of a home exercise program in patients versus supervised exercise, either in isolation or with usual physiotherapy. The PEDro scale and the Cochrane Collaboration tool were used to evaluate the quality of the studies and the risk of bias, respectively. Exercise Interventions Content Assessment, using the proforma provided in the CERT, and adherence were extracted from the included manuscripts. Data were extracted by two independent assessors using a standardized form. Meta-analyses were conducted with the R statistical program using fixed or random effects models according to the heterogeneity assessed with I2 coefficient.

Evidence synthesis: Twelve RCTs (N.=475) were included. Home self-training was similar and no differences were found at 12 weeks from supervised exercise program, either alone or combined with standard physiotherapy treatment on Visual Analogic Scale (VAS) (SMD, 0.92; 95% CI, 0.58 to 1.26, P=0.66); Constant-Murley Score (CS) (SMD, -0.82; 95% CI, -1.05 to -0-60, P=0.64); and Shoulder Pain and Disability Index (SPADI) (SMD, 1; 95% CI, 0.74 to 1.26, P=0.93). It was impossible to include adherence in the meta-analysis due to the small number of studies reporting this data and the heterogeneity of the criteria for accepting adequate adherence to the prescribed exercise program.

Conclusions: Home self-training might be equally effective as outpatient and supervised exercise, isolated or combined with the usual physiotherapy, in terms of primary outcomes. However, the lack of information on adherence rates, the content of the exercise or how it is performed is worrying. Furthermore, the heterogeneity of the criteria related to treatment adherence and compliance indicates that more literature is needed to relate the effect produced with the type of exercise and therapeutic adherence.

简介:基于物理治疗的保守治疗是非撕裂性肩袖相关肩痛(RCSP)的首选。尽管有几项研究证明了治疗性运动的积极作用,但在监督下的运动与家庭自我训练的影响或坚持程度等方面仍不清楚。目的是研究家庭运动项目与监督运动的效果,无论是单独的还是与标准物理治疗相结合。证据获取:检索截至2025年3月的Web of Science、PubMed、SCOPUS、EMBASE、试验注册库和相关文章的参考文献列表。只纳入了随机对照试验,旨在比较家庭锻炼计划对患者的影响与监督锻炼的效果,无论是单独锻炼还是常规物理治疗。PEDro量表和Cochrane协作工具分别用于评估研究质量和偏倚风险。使用CERT提供的形式进行运动干预内容评估,并从纳入的手稿中提取依从性。数据由两名独立评估人员使用标准化表格提取。根据I2系数评估异质性,采用固定或随机效应模型,采用R统计程序进行meta分析。证据综合:纳入12项随机对照试验(n =475)。在视觉类比量表(VAS)上,家庭自我训练与监督运动计划相似,在12周时没有发现差异,无论是单独的还是联合标准物理治疗(SMD, 0.92; 95% CI, 0.58 ~ 1.26, P=0.66);Constant-Murley评分(CS) (SMD, -0.82; 95% CI, -1.05 ~ -0-60, P=0.64);肩痛与失能指数(SPADI) (SMD, 1; 95% CI, 0.74 ~ 1.26, P=0.93)。由于报告这一数据的研究数量较少,并且接受充分坚持规定的锻炼计划的标准存在异质性,因此不可能将坚持纳入荟萃分析。结论:就主要结果而言,家庭自我训练可能与门诊和监督运动一样有效,单独或结合常规物理治疗。然而,缺乏关于坚持率、锻炼内容或如何进行的信息令人担忧。此外,与治疗依从性和依从性相关的标准的异质性表明,需要更多的文献来将运动类型和治疗依从性产生的效果联系起来。
{"title":"Effect of home exercise programs in patients with non-tears rotator cuff-related shoulder pain: a systematic review and meta-analysis.","authors":"Sergio Hernández-Sánchez, José V Segura-Heras, Paula Andreu-Conde, Manuel Albornoz-Cabello, Luis Espejo-Antúnez, José V Toledo-Marhuenda","doi":"10.23736/S1973-9087.25.08607-1","DOIUrl":"10.23736/S1973-9087.25.08607-1","url":null,"abstract":"<p><strong>Introduction: </strong>Conservative treatment based on physiotherapy is the first option for non-tears rotator cuff related shoulder pain (RCSP). Although several studies demonstrate the positive effect of therapeutic exercise, aspects such as the influence of supervised exercises versus home-self training or the level of adherence are still unclear. The objective is to study the effect of home exercise programs compared to supervised exercise, either alone or combined with standard physiotherapy treatment.</p><p><strong>Evidence acquisition: </strong>Web of Science, PubMed, SCOPUS, EMBASE, trials registries and reference lists with relevant articles were searched up to March 2025. Only randomized controlled trials were included that aimed to compare the effect of a home exercise program in patients versus supervised exercise, either in isolation or with usual physiotherapy. The PEDro scale and the Cochrane Collaboration tool were used to evaluate the quality of the studies and the risk of bias, respectively. Exercise Interventions Content Assessment, using the proforma provided in the CERT, and adherence were extracted from the included manuscripts. Data were extracted by two independent assessors using a standardized form. Meta-analyses were conducted with the R statistical program using fixed or random effects models according to the heterogeneity assessed with I<sup>2</sup> coefficient.</p><p><strong>Evidence synthesis: </strong>Twelve RCTs (N.=475) were included. Home self-training was similar and no differences were found at 12 weeks from supervised exercise program, either alone or combined with standard physiotherapy treatment on Visual Analogic Scale (VAS) (SMD, 0.92; 95% CI, 0.58 to 1.26, P=0.66); Constant-Murley Score (CS) (SMD, -0.82; 95% CI, -1.05 to -0-60, P=0.64); and Shoulder Pain and Disability Index (SPADI) (SMD, 1; 95% CI, 0.74 to 1.26, P=0.93). It was impossible to include adherence in the meta-analysis due to the small number of studies reporting this data and the heterogeneity of the criteria for accepting adequate adherence to the prescribed exercise program.</p><p><strong>Conclusions: </strong>Home self-training might be equally effective as outpatient and supervised exercise, isolated or combined with the usual physiotherapy, in terms of primary outcomes. However, the lack of information on adherence rates, the content of the exercise or how it is performed is worrying. Furthermore, the heterogeneity of the criteria related to treatment adherence and compliance indicates that more literature is needed to relate the effect produced with the type of exercise and therapeutic adherence.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":"61 4","pages":"655-668"},"PeriodicalIF":3.4,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12794299/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145388164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Virtual reality-based interventions enhance functional status, balance and muscle strength in patients with ankle instability: a systematic review with meta-analysis of randomized controlled trials. 基于虚拟现实的干预可以增强踝关节不稳定患者的功能状态、平衡和肌肉力量:一项随机对照试验荟萃分析的系统综述。
IF 3.4 3区 医学 Q1 REHABILITATION Pub Date : 2025-06-01 DOI: 10.23736/S1973-9087.25.08869-0
Manuel García-Sánchez, Esteban Obrero-Gaitán, M Carmen López-Ruiz, Ángeles Díaz-Fernández, M Catalina Osuna-Pérez, Irene Cortés-Pérez

Introduction: Ankle instability reduces functional status in athletes and overall population after orthopedic ankle injuries. Complementary to physical therapy approaches, virtual reality-based interventions (VRBI) that promote exercises in ludic and gamified environments, are being used in reducing ankle instability during ankle rehabilitation. The aim of this systematic review with meta-analysis was to assess the effectiveness of VRBI in improving ankle function status, postural balance and muscle strength in patients with ankle instability.

Evidence acquisition: A systematic review with meta-analysis, previously registered in PROSPERO (CRD42023460797) was conducted aligned with the PRISMA guidelines. Literature search was performed in PubMed Medline, SCOPUS, WOS, CINAHL and PEDro without year of publication and language restrictions up to November 2024. Randomized controlled trials (RCTs) including patients with ankle instability which assessed the effectiveness of VRBI, compared to others, on ankle function status, postural balance, muscle strength, were included. Methodological quality and risk of bias were assessed using the PEDro Scale. Pooled effect was calculated with the Cohen's standardized mean difference (SMD) and its 95% confidence interval (95% CI) in random-effects models, or mean difference (MD) if studies used the same measure. All methodological phases of this meta-analysis were conducted by peers.

Evidence synthesis: Twelve RCTs, providing data from 555 participants with ankle instability (89% males with a mean age of 21.8±6.2 years), were included. The mean methodological quality of the studies included was moderate (5.8±1.3 in the PEDro scale). Our meta-analysis showed that VRBI is largely effective in increasing ankle function status (SMD=0.86; 95% CI 0.24 to 1.49; P=0.007), static (SMD=1.6; 95% CI 0.74 to 2.4; P<0.001) and dynamic balance (SMD=0.81; 95% CI 0.36 to 1.25; P<0.001), and strength of muscles involved in plantar flexion (MD=5.76; 95% CI 0.22 to 11.3; P=0.042) and eversion movements (MD=1.7; 95% CI 0.5 to 2.9; P=0.005).

Conclusions: VRBI is a safe and effective therapy for improving ankle function status, static and dynamic balance and strength of the muscles involved in plantar flexion eversion movements in patients with ankle instability.

踝关节不稳定降低了运动员和整体人群在骨科踝关节损伤后的功能状态。作为物理治疗方法的补充,基于虚拟现实的干预(VRBI)在搞笑和游戏化的环境中促进锻炼,被用于减少踝关节康复期间的踝关节不稳定。本系统综述结合meta分析的目的是评估VRBI在改善踝关节不稳定患者的踝关节功能状态、姿势平衡和肌肉力量方面的有效性。证据获取:根据PRISMA指南,对先前在PROSPERO注册的(CRD42023460797)进行了系统评价和荟萃分析。在PubMed Medline、SCOPUS、WOS、CINAHL和PEDro中进行文献检索,不受出版年份和语言限制,截止到2024年11月。随机对照试验(rct)纳入了踝关节不稳定患者,评估了VRBI与其他方法相比在踝关节功能状态、姿势平衡、肌肉力量方面的有效性。采用PEDro量表评估方法学质量和偏倚风险。合并效应是用随机效应模型中的Cohen标准平均差(SMD)及其95%置信区间(95% CI)来计算的,如果研究使用相同的测量方法,则用平均差(MD)来计算。本荟萃分析的所有方法学阶段均由同行进行。证据综合:纳入12项随机对照试验,提供555名踝关节不稳患者的数据(89%为男性,平均年龄21.8±6.2岁)。纳入研究的平均方法学质量为中等(PEDro评分为5.8±1.3)。我们的meta分析显示,VRBI在改善踝关节功能状态(SMD=0.86; 95% CI 0.24 ~ 1.49; P=0.007)和静止(SMD=1.6; 95% CI 0.74 ~ 2.4)方面有很大的效果。结论:VRBI是一种安全有效的治疗方法,可改善踝关节不稳定患者踝关节功能状态、静态和动态平衡以及参与足底屈伸运动的肌肉力量。
{"title":"Virtual reality-based interventions enhance functional status, balance and muscle strength in patients with ankle instability: a systematic review with meta-analysis of randomized controlled trials.","authors":"Manuel García-Sánchez, Esteban Obrero-Gaitán, M Carmen López-Ruiz, Ángeles Díaz-Fernández, M Catalina Osuna-Pérez, Irene Cortés-Pérez","doi":"10.23736/S1973-9087.25.08869-0","DOIUrl":"10.23736/S1973-9087.25.08869-0","url":null,"abstract":"<p><strong>Introduction: </strong>Ankle instability reduces functional status in athletes and overall population after orthopedic ankle injuries. Complementary to physical therapy approaches, virtual reality-based interventions (VRBI) that promote exercises in ludic and gamified environments, are being used in reducing ankle instability during ankle rehabilitation. The aim of this systematic review with meta-analysis was to assess the effectiveness of VRBI in improving ankle function status, postural balance and muscle strength in patients with ankle instability.</p><p><strong>Evidence acquisition: </strong>A systematic review with meta-analysis, previously registered in PROSPERO (CRD42023460797) was conducted aligned with the PRISMA guidelines. Literature search was performed in PubMed Medline, SCOPUS, WOS, CINAHL and PEDro without year of publication and language restrictions up to November 2024. Randomized controlled trials (RCTs) including patients with ankle instability which assessed the effectiveness of VRBI, compared to others, on ankle function status, postural balance, muscle strength, were included. Methodological quality and risk of bias were assessed using the PEDro Scale. Pooled effect was calculated with the Cohen's standardized mean difference (SMD) and its 95% confidence interval (95% CI) in random-effects models, or mean difference (MD) if studies used the same measure. All methodological phases of this meta-analysis were conducted by peers.</p><p><strong>Evidence synthesis: </strong>Twelve RCTs, providing data from 555 participants with ankle instability (89% males with a mean age of 21.8±6.2 years), were included. The mean methodological quality of the studies included was moderate (5.8±1.3 in the PEDro scale). Our meta-analysis showed that VRBI is largely effective in increasing ankle function status (SMD=0.86; 95% CI 0.24 to 1.49; P=0.007), static (SMD=1.6; 95% CI 0.74 to 2.4; P<0.001) and dynamic balance (SMD=0.81; 95% CI 0.36 to 1.25; P<0.001), and strength of muscles involved in plantar flexion (MD=5.76; 95% CI 0.22 to 11.3; P=0.042) and eversion movements (MD=1.7; 95% CI 0.5 to 2.9; P=0.005).</p><p><strong>Conclusions: </strong>VRBI is a safe and effective therapy for improving ankle function status, static and dynamic balance and strength of the muscles involved in plantar flexion eversion movements in patients with ankle instability.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":"61 3","pages":"551-563"},"PeriodicalIF":3.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12410587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144947789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Repetitive peripheral magnetic stimulation for pain, disability, and kinesiophobia in patients with chronic musculoskeletal pain: a systematic review and meta-analysis. 重复性外周磁刺激治疗慢性肌肉骨骼疼痛患者的疼痛、残疾和运动恐惧症:系统回顾和荟萃分析。
IF 3.4 3区 医学 Q1 REHABILITATION Pub Date : 2025-06-01 Epub Date: 2025-06-12 DOI: 10.23736/S1973-9087.25.08442-4
Jiaxin Pan, Yanbing Jia, Kuicheng Li, Xiaoyan Liu, Zhichao Liu, Zhenyang Cui, Linrong Liao, Yingxiu Diao, Hao Liu

Introduction: Repetitive peripheral magnetic stimulation (rPMS) is a non-invasive and painless approach developed for therapeutic intervention in clinical rehabilitation. Chronic musculoskeletal pain (CMP) originates from the musculoskeletal system and leads to disability and fear of pain. It may be an option for CMP treatment, but its effectiveness is still unclear.

Evidence acquisition: PubMed, PEDro, the Cochrane Library, Web of Science, and Embase were searched for relevant literatures according to strict inclusion and exclusion criteria on May 26th, 2023.

Evidence synthesis: The methodology quality of the included studies was assessed using the Cochrane Collaboration's Risk of Bias tool (ROB 2.0) and the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) system. The cumulative effects of available data were processed for a meta-analysis using RevMan software. Eight RCTs with 177 participants were included. All studies were assessed as having some concerns regarding the risk of bias. rPMS significantly reduced pain intensity compared with the control, with a standardized mean difference (SMD) across visual analogue scales (VAS) and numerical rating scales (NRS) was -1.16 (95% CI: -1.56 to -0.76, I2=21%, very low-quality evidence), indicating effective pain relief. For subgroup analysis of patients with chronic low back pain (CLBP), the meta-analysis revealed a remarkable pain relief (SMD=-0.92, 95% CI: -1.67 to -0.17, I2=45%, very low-quality evidence). In addition, rPMS exhibited significant cumulative effects on disability improvement (Oswestry disability index: MD=-6.55, 95% CI: -10.27 to -2.82, I2=0%, very low-quality evidence) but not on kinesiophobia (Tampa scale for kinesiophobia: MD=-1.81, 95% CI: -7.60 to 3.98, I2=0%, low quality-evidence).

Conclusions: This meta-analysis demonstrated that rPMS is an effective method for relieving pain and improving disability in the treatment of CMP, especially for patients with CLBP.

简介:重复性外周磁刺激(rPMS)是一种无创、无痛的临床康复治疗干预方法。慢性肌肉骨骼疼痛(CMP)起源于肌肉骨骼系统,导致残疾和对疼痛的恐惧。它可能是CMP治疗的一种选择,但其有效性尚不清楚。证据获取:2023年5月26日,按照严格的纳入和排除标准,检索PubMed、PEDro、Cochrane Library、Web of Science、Embase等相关文献。证据综合:采用Cochrane协作的偏倚风险工具(ROB 2.0)和GRADE(分级推荐、评估、发展和评价)系统评估纳入研究的方法学质量。利用RevMan软件对现有数据的累积效应进行meta分析。共纳入8项随机对照试验,共177名受试者。所有的研究都被评估为存在一定的偏倚风险。与对照组相比,rPMS显著降低了疼痛强度,视觉模拟量表(VAS)和数值评定量表(NRS)的标准化平均差(SMD)为-1.16 (95% CI: -1.56至-0.76,I2=21%,极低质量证据),表明疼痛有效缓解。对于慢性腰痛(CLBP)患者的亚组分析,meta分析显示疼痛缓解显著(SMD=-0.92, 95% CI: -1.67至-0.17,I2=45%,极低质量证据)。此外,rPMS对残疾改善表现出显著的累积效应(Oswestry残疾指数:MD=-6.55, 95% CI: -10.27至-2.82,I2=0%,极低质量证据),但对运动恐惧症没有显著的累积效应(运动恐惧症的坦帕量表:MD=-1.81, 95% CI: -7.60至3.98,I2=0%,低质量证据)。结论:本荟萃分析表明,rPMS是缓解CMP疼痛和改善残疾的有效方法,特别是对于CLBP患者。
{"title":"Repetitive peripheral magnetic stimulation for pain, disability, and kinesiophobia in patients with chronic musculoskeletal pain: a systematic review and meta-analysis.","authors":"Jiaxin Pan, Yanbing Jia, Kuicheng Li, Xiaoyan Liu, Zhichao Liu, Zhenyang Cui, Linrong Liao, Yingxiu Diao, Hao Liu","doi":"10.23736/S1973-9087.25.08442-4","DOIUrl":"10.23736/S1973-9087.25.08442-4","url":null,"abstract":"<p><strong>Introduction: </strong>Repetitive peripheral magnetic stimulation (rPMS) is a non-invasive and painless approach developed for therapeutic intervention in clinical rehabilitation. Chronic musculoskeletal pain (CMP) originates from the musculoskeletal system and leads to disability and fear of pain. It may be an option for CMP treatment, but its effectiveness is still unclear.</p><p><strong>Evidence acquisition: </strong>PubMed, PEDro, the Cochrane Library, Web of Science, and Embase were searched for relevant literatures according to strict inclusion and exclusion criteria on May 26<sup>th</sup>, 2023.</p><p><strong>Evidence synthesis: </strong>The methodology quality of the included studies was assessed using the Cochrane Collaboration's Risk of Bias tool (ROB 2.0) and the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) system. The cumulative effects of available data were processed for a meta-analysis using RevMan software. Eight RCTs with 177 participants were included. All studies were assessed as having some concerns regarding the risk of bias. rPMS significantly reduced pain intensity compared with the control, with a standardized mean difference (SMD) across visual analogue scales (VAS) and numerical rating scales (NRS) was -1.16 (95% CI: -1.56 to -0.76, I<sup>2</sup>=21%, very low-quality evidence), indicating effective pain relief. For subgroup analysis of patients with chronic low back pain (CLBP), the meta-analysis revealed a remarkable pain relief (SMD=-0.92, 95% CI: -1.67 to -0.17, I<sup>2</sup>=45%, very low-quality evidence). In addition, rPMS exhibited significant cumulative effects on disability improvement (Oswestry disability index: MD=-6.55, 95% CI: -10.27 to -2.82, I<sup>2</sup>=0%, very low-quality evidence) but not on kinesiophobia (Tampa scale for kinesiophobia: MD=-1.81, 95% CI: -7.60 to 3.98, I<sup>2</sup>=0%, low quality-evidence).</p><p><strong>Conclusions: </strong>This meta-analysis demonstrated that rPMS is an effective method for relieving pain and improving disability in the treatment of CMP, especially for patients with CLBP.</p>","PeriodicalId":12044,"journal":{"name":"European journal of physical and rehabilitation medicine","volume":" ","pages":"572-582"},"PeriodicalIF":3.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12411938/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
European journal of physical and rehabilitation medicine
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1