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Association between methylmalonic acid and prevalence of depression in US adults: evidence from NHANES 2011-2014.
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-02-13 DOI: 10.1080/20008066.2025.2450109
Siqi Li, Wenbin Nan, Zhenyu Peng, Qiong Huang, Qiong Chen, Baimei He

Background: Depression is a prevalent mental disorder with high morbidity and mortality globally. Methylmalonic acid (MMA) is involved in the pathogenesis of numerous diseases. However, it is unclear whether there is an association between MMA and the prevalence of depression.Methods: This study enrolled 7866 US adults from the 2011-2014 survey of the National Health and Nutrition Examination Survey (NHANES). Individuals were categorized into depression group and non-depression group based on Patient's Health Questionnaire-9 (PHQ-9) score. The association between MMA concentrations and prevalence of depression was analysed by multivariate logistic and linear regression, restricted cubic spline regression, and subgroup analysis. Mediation analysis was used to explore the role of inflammation in the relationship between MMA and depression.Results: MMA concentrations were higher in participants with depression than those without depression. There was a positive and linear relationship of MMA concentrations with PHQ-9 score and depression risk, respectively. Moreover, the association was stable in most subgroups. Furthermore, inflammatory factors were positively correlated to MMA concentrations and prevalence of depression. In addition, white blood cell, neutrophil and alkaline phosphatase (ALP) mediated the relationship between MMA and depression.Conclusion: Our findings revealed that there was a linear and positive correlation between MMA and the prevalence of depression in US adults, which might be mediated by inflammation.

{"title":"Association between methylmalonic acid and prevalence of depression in US adults: evidence from NHANES 2011-2014.","authors":"Siqi Li, Wenbin Nan, Zhenyu Peng, Qiong Huang, Qiong Chen, Baimei He","doi":"10.1080/20008066.2025.2450109","DOIUrl":"10.1080/20008066.2025.2450109","url":null,"abstract":"<p><p><b>Background</b>: Depression is a prevalent mental disorder with high morbidity and mortality globally. Methylmalonic acid (MMA) is involved in the pathogenesis of numerous diseases. However, it is unclear whether there is an association between MMA and the prevalence of depression.<b>Methods</b>: This study enrolled 7866 US adults from the 2011-2014 survey of the National Health and Nutrition Examination Survey (NHANES). Individuals were categorized into depression group and non-depression group based on Patient's Health Questionnaire-9 (PHQ-9) score. The association between MMA concentrations and prevalence of depression was analysed by multivariate logistic and linear regression, restricted cubic spline regression, and subgroup analysis. Mediation analysis was used to explore the role of inflammation in the relationship between MMA and depression.<b>Results</b>: MMA concentrations were higher in participants with depression than those without depression. There was a positive and linear relationship of MMA concentrations with PHQ-9 score and depression risk, respectively. Moreover, the association was stable in most subgroups. Furthermore, inflammatory factors were positively correlated to MMA concentrations and prevalence of depression. In addition, white blood cell, neutrophil and alkaline phosphatase (ALP) mediated the relationship between MMA and depression.<b>Conclusion:</b> Our findings revealed that there was a linear and positive correlation between MMA and the prevalence of depression in US adults, which might be mediated by inflammation.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2450109"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143406028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dissociative experiences in individuals with subclinical psychosis and a history of developmental trauma: a qualitative study.
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-03-11 DOI: 10.1080/20008066.2025.2472473
Eirini Aikaterini Melegkovits, Ava Mason, Jordan Reid, Hind Akooly, Paul Jung, Michael Bloomfield

Background: Among individuals with psychotic experiences, those with a history of developmental trauma face greater symptom severity and worse clinical outcomes compared to those without. Dissociation constitutes a prominent, characteristic of this group's clinical presentation, whose nuances and associated characteristics remain however understudied in psychosis research. We aimed to address this gap by conducting a qualitative study to investigate the phenomenology, context, and impact of dissociative experiences in individuals with subclinical psychosis and a history of developmental trauma.Methods: 25 UK-based participants with a history of developmental trauma and meeting criteria for subclinical psychosis, based on the CAPE-15, were recruited via social media. Participants attended semi-structured interviews online, which were transcribed verbatim and analysed with thematic analysis by two researchers.Results: Thematic analysis yielded the following themes: (1) Phenomenology of Dissociation; (2) Context of Dissociation; (3) Impact of Dissociation; (4) Dissociation and Psychotic-like Phenomena. Participants described experiences of detachment and compartmentalisation, which when experienced were confusing and often distressing. Dissociation was linked to affective experiences, their history of developmental trauma and psychotic-like experiences.Conclusion: This study elucidates the complex and varied nature of dissociative experiences in individuals with subclinical psychosis with a history of developmental trauma. These findings highlight the need for further research to understand the manifestation of dissociation in this population and the links with distress and other aspects of psychopathology. Importantly, it is essential to use this understanding to inform the development of interventions and improve clinical recognition and management.

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引用次数: 0
The role of prenatal stress and maternal trauma responses in predicting children's mental health during war. 产前压力和母体创伤反应在预测战争期间儿童心理健康方面的作用。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-02-28 DOI: 10.1080/20008066.2025.2468542
Karen Yirmiya, Amit Klein, Shir Atzil, Noa Yakirevich-Amir, Rena Bina, Inbal Reuveni

Background: The negative effects of prenatal stress on children's development and the buffering effects of maternal behaviour are well documented. However, specific maternal responses to trauma, particularly among families experiencing cumulative stressors during pregnancy and early childhood, remain less understood.Objective: This study investigated the interplay between prenatal stress in the context of the coronavirus disease 2019 (COVID-19) pandemic and consequent maternal trauma responses and children's difficulties in the context of war-related trauma.Methods: We recruited 318 pregnant women in Israel during the first wave of the COVID-19 pandemic (Time 1). Prenatal depression, anxiety, and COVID-related stress symptoms were assessed. When children were approximately 3.5 years old (SD = 0.02), the mothers were asked to report on parental responses related to the ongoing war and their child's emotional and behavioural difficulties (Time 2). Structural equation modelling was used to examine how maternal trauma responses mediate the association between prenatal stress-related mental health symptoms and children's difficulties during war.Results: Maternal prenatal depressive, anxious, and COVID-19-related stress symptoms predicted maladaptive maternal trauma responses during the war, which in turn were associated with increased emotional and behavioural problems in their children. Among the specific maternal trauma-related responses examined, cognitive avoidance and overprotectiveness were the only behavioural responses during the war significantly associated with children's difficulties.Conclusions: Our study highlights the impact of pandemic-related prenatal stress on maternal responses and children's difficulties during war, emphasizing the importance of identifying at-risk families as well as developing targeted interventions that mitigate negative parenting responses, particularly avoidance and overprotection.

{"title":"The role of prenatal stress and maternal trauma responses in predicting children's mental health during war.","authors":"Karen Yirmiya, Amit Klein, Shir Atzil, Noa Yakirevich-Amir, Rena Bina, Inbal Reuveni","doi":"10.1080/20008066.2025.2468542","DOIUrl":"10.1080/20008066.2025.2468542","url":null,"abstract":"<p><p><b>Background:</b> The negative effects of prenatal stress on children's development and the buffering effects of maternal behaviour are well documented. However, specific maternal responses to trauma, particularly among families experiencing cumulative stressors during pregnancy and early childhood, remain less understood.<b>Objective:</b> This study investigated the interplay between prenatal stress in the context of the coronavirus disease 2019 (COVID-19) pandemic and consequent maternal trauma responses and children's difficulties in the context of war-related trauma.<b>Methods:</b> We recruited 318 pregnant women in Israel during the first wave of the COVID-19 pandemic (Time 1). Prenatal depression, anxiety, and COVID-related stress symptoms were assessed. When children were approximately 3.5 years old (<i>SD</i> = 0.02), the mothers were asked to report on parental responses related to the ongoing war and their child's emotional and behavioural difficulties (Time 2). Structural equation modelling was used to examine how maternal trauma responses mediate the association between prenatal stress-related mental health symptoms and children's difficulties during war.<b>Results:</b> Maternal prenatal depressive, anxious, and COVID-19-related stress symptoms predicted maladaptive maternal trauma responses during the war, which in turn were associated with increased emotional and behavioural problems in their children. Among the specific maternal trauma-related responses examined, cognitive avoidance and overprotectiveness were the only behavioural responses during the war significantly associated with children's difficulties.<b>Conclusions:</b> Our study highlights the impact of pandemic-related prenatal stress on maternal responses and children's difficulties during war, emphasizing the importance of identifying at-risk families as well as developing targeted interventions that mitigate negative parenting responses, particularly avoidance and overprotection.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2468542"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11873953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experiences and impact of moral injury in prisons. 监狱道德伤害的经验与影响。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-01-13 DOI: 10.1080/20008066.2024.2445899
Victoria Williamson, Dominic Murphy, Danielle Lamb, Radha Kothari, Derek Tracy, Neil Greenberg

Moral injury is the persistent mental or emotional distress resulting from events that challenge one's moral beliefs. It is characterised by intense shame, guilt, worthlessness, disgust or anger and can contribute towards the development of serious mental disorders. The nature of working in prisons means that staff often face physically and psychologically challenging scenarios, and prison staff report high rates of mental ill-health and suicidal thoughts. Equally, detainees may be especially vulnerable to moral injury-related mental health difficulties having engaged in illicit actions and been found guilty by a jury of their peers as well as, in high profile cases, the court of public opinion. Despite this, there is an evidence gap about the extent of moral injury in both prison staff and detainee populations, and about how prison staff/detainees can be better supported. How struggling with moral injury may be linked to reoffending amongst detainees and burnout or resignations in prisons staff is currently unknown. In resource strapped prison settings, emerging treatments for moral injury-related mental health difficulties are unlikely to be appropriate or feasible. In this article, we highlight the contexts in which moral injury may arise; the unique challenges to treatment and support for moral injury in prison settings; and offer targeted recommendations for future research and clinical practice.

道德伤害是由于挑战一个人的道德信仰的事件而造成的持续的精神或情感上的痛苦。它的特征是强烈的羞耻、内疚、毫无价值、厌恶或愤怒,并可能导致严重精神障碍的发展。监狱工作的性质意味着工作人员经常面临身体和心理上的挑战,监狱工作人员报告精神疾病和自杀念头的比例很高。同样,被拘留者可能特别容易受到与精神健康问题有关的精神伤害,因为他们从事了非法行为,并被同侪组成的陪审团判定有罪,在备受关注的案件中,也被舆论法庭判定有罪。尽管如此,关于监狱工作人员和被拘留者的道德伤害程度,以及如何更好地支持监狱工作人员/被拘留者,都存在证据差距。与道德伤害作斗争与被拘留者的重新犯罪以及监狱工作人员的倦怠或辞职之间的关系目前尚不清楚。在资源紧张的监狱环境中,针对与道德伤害有关的精神健康困难的新疗法不太可能是适当的或可行的。在这篇文章中,我们强调了道德伤害可能出现的背景;监狱环境中精神创伤治疗和支持的独特挑战;并为未来的研究和临床实践提供有针对性的建议。
{"title":"Experiences and impact of moral injury in prisons.","authors":"Victoria Williamson, Dominic Murphy, Danielle Lamb, Radha Kothari, Derek Tracy, Neil Greenberg","doi":"10.1080/20008066.2024.2445899","DOIUrl":"10.1080/20008066.2024.2445899","url":null,"abstract":"<p><p>Moral injury is the persistent mental or emotional distress resulting from events that challenge one's moral beliefs. It is characterised by intense shame, guilt, worthlessness, disgust or anger and can contribute towards the development of serious mental disorders. The nature of working in prisons means that staff often face physically and psychologically challenging scenarios, and prison staff report high rates of mental ill-health and suicidal thoughts. Equally, detainees may be especially vulnerable to moral injury-related mental health difficulties having engaged in illicit actions and been found guilty by a jury of their peers as well as, in high profile cases, the court of public opinion. Despite this, there is an evidence gap about the extent of moral injury in both prison staff and detainee populations, and about how prison staff/detainees can be better supported. How struggling with moral injury may be linked to reoffending amongst detainees and burnout or resignations in prisons staff is currently unknown. In resource strapped prison settings, emerging treatments for moral injury-related mental health difficulties are unlikely to be appropriate or feasible. In this article, we highlight the contexts in which moral injury may arise; the unique challenges to treatment and support for moral injury in prison settings; and offer targeted recommendations for future research and clinical practice.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2445899"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11731261/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142970243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Towards a better definition of nociplastic pain conditions: a psychological grounded study on fibromyalgia, chronic headache and vulvodynia.
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-02-13 DOI: 10.1080/20008066.2025.2461434
Martina Mesce, Filippo Maria Nimbi, Piercarlo Sarzi-Puttini, Carlo Lai, Federica Galli

Background: This study investigates the psychological underpinnings of chronic pain conditions, specifically fibromyalgia, chronic headache, vulvodynia, and mixed condition (consisting of fibromyalgia in comorbidity with chronic headache and/or vulvodynia), with a focus on nociplastic pain mechanisms.Objective: The aim of the study is to better understand the psychological functioning of women with different chronic pain conditions to identify and discuss similarities and differences. In particular, we aim to explore any significant differences in the domain of traumatic experiences, in global defensive functioning, and in the domain of alexithymia among the evaluated groups. Further, the 4 groups with chronic pain will be compared with a healthy control group.Methods: A sample of 1006 Italian women diagnosed with chronic pain participated in the study, categorized into four clinical groups and a healthy control group. Measures were assessed using self-report measures, in particular: Traumatic Experiences Checklist, Defense Mechanism Rating Scales, and Toronto Alexithymia Scale.Results: There are significant differences among groups, with mixed conditions exhibiting the highest levels of traumatic experiences, particularly emotional neglect and physical threats. Fibromyalgia and mixed condition groups displayed greater reliance on neurotic defense mechanisms. Additionally, fibromyalgia and mixed condition participants exhibited higher levels of alexithymia, indicating difficulties in emotional processing.Conclusions: These findings underscore the complex interplay between psychological factors and nociplastic pain conditions, emphasizing the importance of personalized psychological interventions in managing nociplastic pain. The study highlights the need for multidisciplinary approaches to nociplastic pain treatment, considering the diverse psychological profiles of affected individuals.

{"title":"Towards a better definition of nociplastic pain conditions: a psychological grounded study on fibromyalgia, chronic headache and vulvodynia.","authors":"Martina Mesce, Filippo Maria Nimbi, Piercarlo Sarzi-Puttini, Carlo Lai, Federica Galli","doi":"10.1080/20008066.2025.2461434","DOIUrl":"10.1080/20008066.2025.2461434","url":null,"abstract":"<p><p><b>Background:</b> This study investigates the psychological underpinnings of chronic pain conditions, specifically fibromyalgia, chronic headache, vulvodynia, and mixed condition (consisting of fibromyalgia in comorbidity with chronic headache and/or vulvodynia), with a focus on nociplastic pain mechanisms.<b>Objective:</b> The aim of the study is to better understand the psychological functioning of women with different chronic pain conditions to identify and discuss similarities and differences. In particular, we aim to explore any significant differences in the domain of traumatic experiences, in global defensive functioning, and in the domain of alexithymia among the evaluated groups. Further, the 4 groups with chronic pain will be compared with a healthy control group.<b>Methods:</b> A sample of 1006 Italian women diagnosed with chronic pain participated in the study, categorized into four clinical groups and a healthy control group. Measures were assessed using self-report measures, in particular: Traumatic Experiences Checklist, Defense Mechanism Rating Scales, and Toronto Alexithymia Scale.<b>Results:</b> There are significant differences among groups, with mixed conditions exhibiting the highest levels of traumatic experiences, particularly emotional neglect and physical threats. Fibromyalgia and mixed condition groups displayed greater reliance on neurotic defense mechanisms. Additionally, fibromyalgia and mixed condition participants exhibited higher levels of alexithymia, indicating difficulties in emotional processing.<b>Conclusions:</b> These findings underscore the complex interplay between psychological factors and nociplastic pain conditions, emphasizing the importance of personalized psychological interventions in managing nociplastic pain. The study highlights the need for multidisciplinary approaches to nociplastic pain treatment, considering the diverse psychological profiles of affected individuals.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2461434"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143406260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Self-compassion, self-coldness, and social support and their relationship with depression, anxiety, and PTSD symptoms following a massive terror attack: a prospective study.
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-02-17 DOI: 10.1080/20008066.2025.2461948
Efrat Barel, Lubna Tannous-Haddad, Orna Tzischinsky

Background: On 7 October 2023, Israel suffered a massive deadly terror attack with 1400 civilians murdered and 240 kidnapped. Recent studies have documented an increase in depression, anxiety, and posttraumatic symptoms in the aftermath of the attack. In the area of trauma, it has been shown that while some individuals are vulnerable to developing psychopathology following exposure to a traumatic event, the majority are not.Objective: In the present prospective study, we examined the contributions of internal (self-compassion and self-coldness) and external (social support) resources to depression, anxiety, and posttraumatic symptoms among civilians following a massive terror attack.Method: A total of 250 participants - 126 females (50.4%) and 124 males (49.6%); 156 Jews (62.4%) and 94 Arabs (37.6%) - aged 21-60 (M  = 41.7, SD = 10.63) completed questionnaires at two time points: T1 was in September 2023 (3-4 weeks before the attack) and T2 was in February-March 2024 (19-20 weeks after the attack). Participants were assessed using the Multidimensional Scale of Perceived Social Support (MSPSS), Self-Compassion Scale - Short Form (SCS-SF), Depression, Anxiety, and Stress Scale-21 Items (DASS-21), and International Trauma Questionnaire (ITQ).Results: Self-compassion and social support were negatively associated with depression and anxiety, while self-coldness was positively associated with depression and anxiety. In addition, self-coldness uniquely contributed to the prediction of psychopathological outcomes, including the sense of threat symptoms cluster of posttraumatic stress disorder, beyond known risk factors.Conclusions: Our study highlights the role of self-coldness as a vulnerability factor for civilians following a terror attack. It is important to view the distinct facets of self-compassion as a therapeutic target when building both intervention and prevention programs for people exposed directly and indirectly to trauma.

{"title":"Self-compassion, self-coldness, and social support and their relationship with depression, anxiety, and PTSD symptoms following a massive terror attack: a prospective study.","authors":"Efrat Barel, Lubna Tannous-Haddad, Orna Tzischinsky","doi":"10.1080/20008066.2025.2461948","DOIUrl":"10.1080/20008066.2025.2461948","url":null,"abstract":"<p><p><b>Background:</b> On 7 October 2023, Israel suffered a massive deadly terror attack with 1400 civilians murdered and 240 kidnapped. Recent studies have documented an increase in depression, anxiety, and posttraumatic symptoms in the aftermath of the attack. In the area of trauma, it has been shown that while some individuals are vulnerable to developing psychopathology following exposure to a traumatic event, the majority are not.<b>Objective:</b> In the present prospective study, we examined the contributions of internal (self-compassion and self-coldness) and external (social support) resources to depression, anxiety, and posttraumatic symptoms among civilians following a massive terror attack.<b>Method:</b> A total of 250 participants - 126 females (50.4%) and 124 males (49.6%); 156 Jews (62.4%) and 94 Arabs (37.6%) - aged 21-60 (<i>M</i>  = 41.7, <i>SD</i> = 10.63) completed questionnaires at two time points: T1 was in September 2023 (3-4 weeks before the attack) and T2 was in February-March 2024 (19-20 weeks after the attack). Participants were assessed using the Multidimensional Scale of Perceived Social Support (MSPSS), Self-Compassion Scale - Short Form (SCS-SF)<b>,</b> Depression, Anxiety, and Stress Scale-21 Items (DASS-21), and International Trauma Questionnaire (ITQ).<b>Results:</b> Self-compassion and social support were negatively associated with depression and anxiety, while self-coldness was positively associated with depression and anxiety. In addition, self-coldness uniquely contributed to the prediction of psychopathological outcomes, including the sense of threat symptoms cluster of posttraumatic stress disorder, beyond known risk factors.<b>Conclusions:</b> Our study highlights the role of self-coldness as a vulnerability factor for civilians following a terror attack. It is important to view the distinct facets of self-compassion as a therapeutic target when building both intervention and prevention programs for people exposed directly and indirectly to trauma.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2461948"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11834774/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143432737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementing scalable face-to-face and digital interventions among forcibly displaced persons from Ukraine in Europe: protocol of The U-RISE Project.
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-02-27 DOI: 10.1080/20008066.2025.2468117
Karl J Weinreich, Iryna Frankova, Natalie Maksymets, Corrado Barbui, Vitalii Klymchuk, Trudy Mooren, Emilia Olechno, Marianna Purgato, Marit Sijbrandij, Anke B Witteveen, Els van der Ven

Background: The full-scale Russian invasion of Ukraine on 24 February 2022 has led to millions of forcibly displaced persons (FDPs) within Ukraine and other European countries. Due to war-related exposure and displacement adversities, this group is at significant risk of developing depression, anxiety, post-traumatic stress disorder, and other mental health problems. Systemic barriers, including insufficiently equipped mental health systems and language barriers, prevent FDPs from receiving adequate mental health and psychosocial support (MHPSS). Scalable interventions delivered in person by non-specialist helpers, or digitally, provide opportunities to scale up the MHPSS response.Objectives: This paper aims to provide an overview of the 'Ukraine's displaced people in the EU: Reach out, Implement, Scale-up and Evaluate interventions promoting mental wellbeing' (U-RISE) project. U-RISE aims to improve the mental wellbeing of FDPs from Ukraine by establishing a network of Ukrainian mental health professionals, building sustainable capacity for provision and supporting implementation of scalable face-to-face and digital mental health interventions adapted to the specific needs of this population.Method: We build capacity for and implement scalable face-to-face interventions, including Problem Management Plus, Self Help Plus, and Multi-family Approach, for FDPs from Ukraine in Poland, Slovakia and Romania. Digital interventions, including the Doing What Matters in Times of Stress digital guide and a Telegram-based chatbot 'Friend' using principles of Psychological First Aid, are being implemented in Europe and Ukraine. To monitor the population's mental wellbeing and impact of the interventions, qualitative needs assessments among mental health providers and FDPs, and quantitative assessments pre- and post-intervention are collected.Conclusion: We provide a framework for the rapid implementation of face-to-face and digital interventions in countries that need to scale up their MHPSS in response to humanitarian or complex emergency crises.

{"title":"Implementing scalable face-to-face and digital interventions among forcibly displaced persons from Ukraine in Europe: protocol of The U-RISE Project.","authors":"Karl J Weinreich, Iryna Frankova, Natalie Maksymets, Corrado Barbui, Vitalii Klymchuk, Trudy Mooren, Emilia Olechno, Marianna Purgato, Marit Sijbrandij, Anke B Witteveen, Els van der Ven","doi":"10.1080/20008066.2025.2468117","DOIUrl":"10.1080/20008066.2025.2468117","url":null,"abstract":"<p><p><b>Background</b>: The full-scale Russian invasion of Ukraine on 24 February 2022 has led to millions of forcibly displaced persons (FDPs) within Ukraine and other European countries. Due to war-related exposure and displacement adversities, this group is at significant risk of developing depression, anxiety, post-traumatic stress disorder, and other mental health problems. Systemic barriers, including insufficiently equipped mental health systems and language barriers, prevent FDPs from receiving adequate mental health and psychosocial support (MHPSS). Scalable interventions delivered in person by non-specialist helpers, or digitally, provide opportunities to scale up the MHPSS response.<b>Objectives</b>: This paper aims to provide an overview of the 'Ukraine's displaced people in the EU: Reach out, Implement, Scale-up and Evaluate interventions promoting mental wellbeing' (U-RISE) project. U-RISE aims to improve the mental wellbeing of FDPs from Ukraine by establishing a network of Ukrainian mental health professionals, building sustainable capacity for provision and supporting implementation of scalable face-to-face and digital mental health interventions adapted to the specific needs of this population.<b>Method:</b> We build capacity for and implement scalable face-to-face interventions, including Problem Management Plus, Self Help Plus, and Multi-family Approach, for FDPs from Ukraine in Poland, Slovakia and Romania. Digital interventions, including the Doing What Matters in Times of Stress digital guide and a Telegram-based chatbot 'Friend' using principles of Psychological First Aid, are being implemented in Europe and Ukraine. To monitor the population's mental wellbeing and impact of the interventions, qualitative needs assessments among mental health providers and FDPs, and quantitative assessments pre- and post-intervention are collected.<b>Conclusion</b>: We provide a framework for the rapid implementation of face-to-face and digital interventions in countries that need to scale up their MHPSS in response to humanitarian or complex emergency crises.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2468117"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11869340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
'We're all in this together': the protective role of belongingness in the contribution of moral injury to mental health among participants in Israel's civil protest movement. 我们同舟共济":归属感在以色列公民抗议运动参与者的精神伤害对心理健康的影响中的保护作用。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-03-10 DOI: 10.1080/20008066.2025.2474374
Yossi Levi-Belz, Yoav Groweiss, Iris Shachar Lavie, Yael Shoval Zuckerman, Carmel Blank

Background: Participating in long-term protests against government actions can affect protesters' mental health and expose protesters to potentially morally injurious events (PMIEs), such as the betrayal by leaders they once trusted. This study aimed to shed light on the potential psychological buffers against the deleterious effects of exposure to PMIEs of betrayal among protesters and to examine the moderating role of belongingness in the relationships between protesters' exposure to PMIEs and stress, PTSD and depression levels.Method: The study sample comprised 4036 Israeli protesters (Mage = 54.27, SD = 12.45; 75.6% females) who took part in the unfolding civil protest movement against the government-led judicial and constitutional overhaul between January 2023 and August 2023. Protesters completed validated self-report questionnaires that included measures of PMIEs, stress, depressive and PTSD symptoms (PTSS).Results: Beyond demographic and protest-related characteristics, exposure to PMIEs of betrayal was found to contribute to both PTSD and depression levels. The indirect effects of PMIE-betrayal on PTSS/depressive symptoms through stress levels were significant, particularly when belongingness levels were low. Thus, a greater sense of PMIE-betrayal contributes to stress symptoms, which, in turn, is linked to higher levels of PTSS and depressive symptoms for protesters having low levels of belongingness.Conclusions: The study's findings highlight the critical contribution of PMIE-betrayal to both PTSS and depression levels, which were mediated by levels of stress. Moreover, experiencing belongingness moderated these relationships. Clinicians treating protesters coping with PTSS and depressive symptoms should also adopt therapeutic aims of establishing belongingness and social support among the protesters.

背景:参加反对政府行为的长期抗议活动会影响抗议者的心理健康,并使抗议者面临潜在的道德伤害事件(PMIEs),例如他们曾经信任的领导人的背叛。本研究旨在揭示潜在的心理缓冲因素,以防止抗议者暴露于背叛事件的有害影响,并研究归属感在抗议者暴露于背叛事件与压力、创伤后应激障碍和抑郁水平之间关系中的调节作用:研究样本包括 4036 名以色列抗议者(Mage = 54.27,SD = 12.45;75.6% 为女性),他们在 2023 年 1 月至 2023 年 8 月期间参加了正在展开的反对政府主导的司法和宪法改革的民间抗议运动。抗议者填写了经过验证的自我报告问卷,其中包括PMIEs、压力、抑郁和创伤后应激障碍症状(PTSS)的测量:结果:除了与人口统计学和抗议相关的特征外,研究还发现暴露于背叛的PMIEs会导致创伤后应激障碍和抑郁水平。PMIE-背叛通过压力水平对创伤后应激障碍/抑郁症状的间接影响是显著的,尤其是当归属感水平较低时。因此,对于归属感水平较低的抗议者来说,较强的PMIE-背叛感会导致压力症状,而压力症状又与较高的创伤后应激障碍和抑郁症状有关:本研究的结论强调了PMIE-背叛对PTSS和抑郁水平的重要影响,而压力水平又是PTSS和抑郁水平的中介。此外,归属感也会调节这些关系。临床医生在治疗应对 PTSS 和抑郁症状的抗议者时,也应采取在抗议者中建立归属感和社会支持的治疗目标。
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引用次数: 0
Childhood abuse and neglect and adult body attitude. 童年虐待、忽视与成人身体态度。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-01-07 DOI: 10.1080/20008066.2024.2439652
Laura Råman, Mia Scheffers, Janet Moeijes, Bertus F Jeronimus

Background: The body is the medium through which humans experience the world, and the body is key to most suffering, healing, and clinical mental diagnoses. Body attitude refers to the affective, cognitive, and behavioural aspects of embodiment, which typically is more negative in clinical samples.Objective: We examine how adult body attitude is associated with self-reported childhood abuse and neglect. We hypothesised that child sexual abuse is associated stronger with a negative adult body attitude than emotional or physical abuse/neglect would. Second, we expected that the association between body attitude and childhood sexual abuse was gender equivalent. Third, we expected a more positive body attitude in men than women after childhood physical abuse/neglect or emotional abuse/neglect.Method: Body attitude was measured with the Dresden Body Image Questionnaire (DBIQ-NL) and the severity and type of childhood trauma with the Childhood Trauma Questionnaire-Short Form (CTQ-SF) in 749 Dutch adults aged 18-77. We fit multiple regression models and focused on childhood abuse and neglect with moderate to severe intensity.Results: Childhood sexual abuse (∼15%), physical neglect (∼14%), emotional abuse (∼20%) and emotional neglect (∼30%) are associated with a more negative body attitude, while childhood physical abuse (moderate/severe, ∼6%) associated with a slightly more positive adult body attitude. Body attitude associations with childhood abuse/neglect were similar for both genders (no moderation).Conclusion: Child maltreatment seems to precede the development of a more negative adult body attitude and more negative body experiences compared to individuals without child maltreatment.

背景:身体是人类体验世界的媒介,身体是大多数痛苦、治疗和临床精神诊断的关键。身体态度是指身体体现的情感、认知和行为方面,在临床样本中通常更为消极。目的:探讨成人身体态度与自我报告的童年虐待和忽视之间的关系。我们假设,与情感或身体虐待/忽视相比,儿童性虐待与成人消极的身体态度联系更紧密。第二,我们预期身体态度与儿童期性虐待之间的关联是性别相等的。第三,我们期望在童年遭受身体虐待/忽视或情感虐待/忽视后,男性的身体态度比女性更积极。方法:采用德累斯顿身体形象问卷(DBIQ-NL)对749名年龄在18-77岁的荷兰成年人进行身体态度调查,采用儿童创伤简易问卷(CTQ-SF)对儿童创伤的严重程度和类型进行调查。我们拟合多元回归模型,重点关注中度至重度的儿童虐待和忽视。结果:儿童期性虐待(~ 15%)、身体忽视(~ 14%)、情感虐待(~ 20%)和情感忽视(~ 30%)与较为消极的身体态度相关,而儿童期身体虐待(中度/重度,~ 6%)与较为积极的成人身体态度相关。身体态度与儿童期虐待/忽视的关联在两性中相似(无节制)。结论:与未遭受儿童虐待的个体相比,儿童虐待似乎先于消极的成人身体态度和消极的身体体验的发展。
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引用次数: 0
Experience of post-traumatic growth among parents of children with biliary atresia undergoing living-related liver transplantation: a descriptive phenomenological study. 胆道闭锁儿童接受活体肝移植的父母创伤后成长的经验:一项描述性现象学研究。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-01-09 DOI: 10.1080/20008066.2024.2447184
ZhiRu Li, FangYan Lu, Li Dong, Li Zheng, JingYun Wu, SiYuan Wu, Yan Wang, HuaFen Wang

Objectives: To explore the experience of post-traumatic growth among parents of children with biliary atresia undergoing living-related liver transplantation.Methods: Participants were recruited within 2 weeks of their child's transplant surgery using purposive sampling. Transcripts were analyzed using Colaizzi's descriptive analysis framework, with collaborative analysis conducted using NVivo 12 software and a post-traumatic growth model.Results: Five themes were identified: (a) experiencing a devastating blow, (b) cognitive reconstruction under overwhelming pain, (c) an arduous journey of decision-making, (d) rebirth in adversity and (e) post-traumatic growth. Parents undergo significant post-traumatic responses to their child's diagnosis of biliary atresia and liver transplantation, marking two major traumatic events. During the diagnostic stage, parents experience intense post-traumatic reactions characterized by emotional fluctuations and intrusive thoughts. The early treatment phase represents a crucial time for parents to transition from `denial of reality' to `accepting diseases'. The process of liver transplantation is also a significant traumatic event, accompanied by a final hope. Parents in the stable period after liver transplantation feel fortunate, hopeful and grateful, and their post-traumatic growth manifests gradually.Conclusions: Parents' experience of post-traumatic growth involves dynamic changes. Tailored intervention strategies should be developed for different stages to enhance their post-traumatic growth and psychological well-being. During the early treatment stage, mental health professionals could provide cognitive interventions to encourage parents to express their negative emotions and guide them to develop positive cognition toward traumatic events. The coping strategies and increasing personal growth are also important. In the postoperative stage, mental health professionals need to fully evaluate the coping styles of parents, and encourage them to establish effective internal coping strategies, while classic gratitude interventions could be given during the post-traumatic growth stage. Future research could involve a longitudinal qualitative study to explore parents' post-traumatic growth experiences at different stages of their children's transplantation process.

目的:探讨行活体肝移植的胆道闭锁患儿家长创伤后成长的体会。方法:采用有目的的抽样方法,在孩子移植手术后2周内招募参与者。转录本使用Colaizzi的描述性分析框架进行分析,并使用NVivo 12软件和创伤后生长模型进行协作分析。结果:确定了五个主题:(a)经历毁灭性的打击,(b)在压倒性痛苦下的认知重建,(c)艰难的决策之旅,(d)逆境中的重生,(e)创伤后成长。当孩子被诊断为胆道闭锁和肝移植时,父母会有明显的创伤后反应,这标志着两个主要的创伤事件。在诊断阶段,父母会经历强烈的创伤后反应,其特征是情绪波动和侵入性思想。早期治疗阶段是父母从“否认现实”过渡到“接受疾病”的关键时期。肝移植的过程也是一个重大的创伤事件,伴随着最后的希望。肝移植术后处于稳定期的父母感到幸运、希望和感恩,创伤后成长逐渐显现。结论:父母创伤后成长经历是动态变化的。应针对不同阶段制定针对性的干预策略,以促进他们的创伤后成长和心理健康。在早期治疗阶段,心理健康专业人员可以提供认知干预,鼓励父母表达负面情绪,引导他们对创伤性事件形成积极认知。应对策略和个人成长也很重要。在术后阶段,心理健康专业人员需要充分评估父母的应对方式,并鼓励他们建立有效的内部应对策略,而在创伤后成长阶段,可以给予经典的感恩干预。未来的研究可能包括纵向定性研究,以探索父母在孩子移植过程中不同阶段的创伤后成长经历。
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引用次数: 0
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European Journal of Psychotraumatology
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