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Methods to induce dissociation and their effects on intrusions and memory: a randomized controlled trauma-film study. 诱导分离的方法及其对创伤和记忆的影响:一项随机对照创伤片研究。
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-10-27 DOI: 10.1080/20008066.2025.2563482
Sarah K Danböck, Sabrina E Hettegger, Laila K Franke, Katharina Hillemeyer, Michael Liedlgruber, Stephan F Miedl, Georg W Alpers, Frank H Wilhelm

Background: Peritraumatic dissociation is thought to contribute to posttraumatic symptoms like intrusions and memory disturbances. However, trauma-analogue studies that examined effects of experimental dissociation-induction on intrusions and memory were inconclusive. To better understand this, a necessary first step is to more systematically compare various induction methods.Objective: We evaluate different dissociation-induction-methods regarding their effectiveness, the intensity and quality of induced dissociation, and their effects on intrusions and memory in a pre-registered randomised-controlled online experiment.Method: Healthy participants (N = 213) were randomised to one of six dissociation-induction-methods: audio-photic stimulation, hypnotic-suggestion, or spiral-staring, each for one-minute or three-minute duration. Participants also completed two further conditions: a non-dissociation-inducing picture task (control condition) and the comparison dissociation-induction-method dot-staring (benchmark condition). Each condition was followed by an aversive ('trauma') film. Peri-film dissociation intensity (measured using an adapted version of the Peritraumatic Dissociative Experiences Questionnaire) and quality, as well as film-specific intrusion-load and memory performance, were assessed. Dissociation-induction-methods were deemed successful if they elicited dissociation levels higher than the control condition and at least as high as the benchmark condition. Only successful dissociation-induction-methods were examined further.Results: Three minutes of hypnotic-suggestion and one minute of spiral-staring successfully induced dissociation during the film, while other methods did not meet the effectiveness threshold. Hypnotic-suggestion led to a greater increase in dissociation intensity than spiral-staring, dissociation induced by spiral-staring was perceived as more uncontrollable and unpleasant. Results did not support an adverse effect of dissociation-induction or dissociation intensity on intrusion-load, but they did support an adverse effect on self-reported and objectively assessed memory performance.Conclusions: Results indicate that hypnotic-suggestion and spiral-staring constitute effective, easy-to-implement, and in principle, neuroimaging-compatible dissociation-induction-methods that allow studying dissociation in the laboratory. The present data did not support the notion that dissociation fosters intrusion formation but provides causal support for effects of dissociation on trauma memory.

背景:创伤周围分离被认为是造成创伤后症状,如侵入和记忆障碍。然而,创伤模拟研究检查实验性分离诱导对入侵和记忆的影响尚无定论。为了更好地理解这一点,必要的第一步是更系统地比较各种归纳方法。目的:通过在线预注册随机对照实验,评价不同解离-诱导方法的有效性、诱导解离的强度和质量,以及对入侵和记忆的影响。方法:健康参与者(N = 213)被随机分配到六种分离诱导方法中的一种:声光刺激、催眠暗示或螺旋凝视,每种方法持续1分钟或3分钟。参与者还完成了另外两个条件:非解离诱导图片任务(控制条件)和比较解离诱导法点注视(基准条件)。每一种情况之后都有一个令人厌恶的(“创伤”)电影。研究人员评估了围膜解离强度(使用创伤围膜解离体验问卷进行测量)和质量,以及特定于电影的入侵负荷和记忆表现。如果解离诱导方法引起的解离水平高于对照条件,并且至少与基准条件一样高,则认为它们是成功的。只有成功的解离-诱导方法被进一步检验。结果:3分钟的催眠暗示和1分钟的螺旋凝视成功地诱导了观影过程中的解离,而其他方法均未达到效果阈值。催眠暗示比螺旋凝视导致的解离强度增加更大,螺旋凝视引起的解离被认为更不可控和不愉快。结果不支持分离诱导或分离强度对入侵负荷的不利影响,但他们确实支持对自我报告和客观评估的记忆表现的不利影响。结论:催眠暗示和螺旋凝视是一种有效的、易于实施的、原则上与神经影像学相容的解离诱导方法,可以在实验室中进行解离研究。目前的数据不支持分离促进入侵形成的观点,但为分离对创伤记忆的影响提供了因果支持。
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引用次数: 0
Mental health during and after the COVID-19 pandemic - a longitudinal study over 42 months in five European countries. COVID-19大流行期间和之后的心理健康——一项在五个欧洲国家进行的为期42个月的纵向研究。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-04-22 DOI: 10.1080/20008066.2025.2488700
Irina Zrnić Novaković, Dean Ajduković, Marina Ajduković, Laura Kenntemich, Annett Lotzin, Ingo Schäfer, Xenia Anastassiou-Hadjicharalambous, Eleftheria Evgeniou, Camila Borges, Margarida Figueiredo-Braga, Moritz Russo, Brigitte Lueger-Schuster

Background: The mental health impact of the COVID-19 pandemic is well documented. However, only a few studies investigated mental health in later phases of the pandemic and after its official end. Moreover, little is known about people's psychological burden related to the pandemic and other global crises post-pandemic.Objective: Study's first objective was to compare mental health outcomes in the general population over the course of the pandemic and ten months post-pandemic. The second objective was to explore people's psychological burden regarding the pandemic, in comparison to current wars, climate crises, inflation, and poor government management and/or corruption in the post-pandemic era.Method: Participants from the general population of Austria, Croatia, Germany, Greece, and Portugal (68.8% female, Mage = 41.55) were assessed online up to four times between June 2020 and March 2024 (baseline sample: N = 7913). Adjustment Disorder New Module - 8 (ADNM-8), Patient Health Questionnaire (PHQ-2), and World Health Organization-Five Well-Being Index (WHO-5) were used to measure adjustment disorder, depression, and well-being. Prevalence rates were calculated and repeated measures ANOVAs applied to assess mental health at four time points. One-way repeated measures ANOVA was run to explore how the different global crises were related to participants' burden.Results: Temporal variations in mental health were evident across four assessment waves, with highest levels of probable adjustment disorder and depression in winter 2020/2021 (T2). A slight improvement of mental health was found at later time points. Current wars and inflation were the greatest sources of psychological burden at the post-pandemic assessment, revealing some cross-country differences.Conclusion: Although mental health differences in the general population were not as pronounced as in the acute phase of the pandemic, psychosocial support is still needed post-pandemic. This is likely to be due to other global crises that take a toll on people's mental health.

背景:COVID-19大流行对心理健康的影响有据可查。然而,只有少数研究调查了大流行后期和正式结束后的心理健康状况。此外,人们对与大流行和大流行后的其他全球危机相关的心理负担知之甚少。目的:研究的第一个目标是比较大流行期间和大流行后10个月普通人群的心理健康结果。第二个目标是探讨与当前战争、气候危机、通货膨胀以及大流行后时代政府管理不善和/或腐败相比,人们对大流行的心理负担。方法:在2020年6月至2024年3月期间,对来自奥地利、克罗地亚、德国、希腊和葡萄牙的普通人群(68.8%为女性,年龄为41.55)的参与者进行了多达四次的在线评估(基线样本:N = 7913)。采用适应障碍新模块-8 (ADNM-8)、患者健康问卷(PHQ-2)和世界卫生组织五幸福感指数(WHO-5)来衡量适应障碍、抑郁和幸福感。计算患病率,并应用重复测量方差分析评估四个时间点的心理健康状况。采用单向重复测量方差分析来探讨不同的全球危机如何与参与者的负担相关。结果:心理健康的时间变化在四个评估波中都很明显,在2020/2021冬季(T2)可能出现的适应障碍和抑郁水平最高。在后来的时间点上发现心理健康略有改善。在大流行后评估中,当前的战争和通货膨胀是心理负担的最大来源,显示出一些跨国差异。结论:虽然普通人群的心理健康差异不像大流行急性期那样明显,但大流行后仍需要社会心理支持。这很可能是由于其他全球性危机对人们的心理健康造成了损害。
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引用次数: 0
Polish adaptation and validation of the International Trauma Questionnaire (ITQ) for PTSD and cPTSD according to ICD-11 in non-clinical and clinical samples. 根据ICD-11,在非临床和临床样本中对PTSD和cPTSD的国际创伤问卷(ITQ)进行调整和验证。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-03-27 DOI: 10.1080/20008066.2025.2468116
Dorota Draczyńska, Łukasz Mokros, Agnieszka Nowakowska, Marta Anczewska

Background: The International Trauma Questionnaire (ITQ) is a validated measure supporting the diagnosis of ICD-11 post-traumatic stress disorder (PTSD) and complex PTSD (cPTSD). It has been translated into 35 languages, also into Polish. Due to the lack of information in the literature about its validation, new Polish version has been re-adapted and validated in the Polish non-clinical and clinical samples of the present study.Objective: The study aimed (1) to adapt the ITQ for use in Polish, (2) to assess the construct validity of ICD-11 PTSD and cPTSD in the Polish ITQ, and (3) to examine the convergent and discriminant validity of the Polish ITQ.Method: The study sample comprised of 452 adults: a non-clinical sample, N = 314, (completed the online version of the questionnaire) and a clinical sample, N = 138, (used a pen-and-paper version). Confirmatory Factor Analysis (CFA) and Latent Class Analysis (LCA) were performed to assess the structure of the ITQ.Results: The CFA supported a two-factor second-order model as the best fit to the data. All factor loadings were statistically significant and reached a satisfactory level. Cronbach's alpha for ITQ (α = 0.887), PTSD (α = 0.810) and DSO (α = 0.875) were good. The LPA revealed four classes: (1) a cPTSD class with elevated PTSD and DSO symptoms; (2) a PTSD class with elevated PTSD symptoms but low scores on the DSO; (3) a DSO class with elevated DSO symptoms but low scores on the PTSD; and (4) a low symptom class with low scores on all symptoms.Conclusion: The amended Polish ITQ has good internal consistency and psychometric properties. The model is well fitted to differentiating PTSD/cPTSD diagnoses according to ICD-11 and is a reliable measure of support for the making of a PTSD/cPTSD diagnosis in the conduct of clinical interview.

背景:国际创伤问卷(ITQ)是支持ICD-11创伤后应激障碍(PTSD)和复杂创伤后应激障碍(cPTSD)诊断的有效措施。它被翻译成35种语言,也被翻译成波兰语。由于文献中缺乏关于其有效性的信息,新的波兰语版本已在本研究的波兰非临床和临床样本中重新改编和验证。目的:本研究旨在(1)调整波兰语ITQ,(2)评估波兰语ITQ中ICD-11 PTSD和cPTSD的结构效度,(3)检验波兰语ITQ的收敛效度和判别效度。方法:研究样本由452名成年人组成,其中非临床样本314名(完成在线问卷)和临床样本138名(使用纸笔问卷)。采用验证性因子分析(CFA)和潜在类分析(LCA)来评估ITQ的结构。结果:CFA支持两因素二阶模型作为数据的最佳拟合。所有因子负荷均具有统计学意义,达到了令人满意的水平。ITQ (α = 0.887)、PTSD (α = 0.810)和DSO (α = 0.875)的Cronbach's alpha均较好。LPA显示了四个等级:(1)cPTSD等级,PTSD和DSO症状升高;(2)一类PTSD患者PTSD症状升高,但DSO得分较低;(3) DSO类患者DSO症状升高,但PTSD得分较低;(4)低症状等级,所有症状得分都很低。结论:修正后的波兰ITQ量表具有良好的内在一致性和心理测量学性质。该模型可以很好地适用于根据ICD-11区分PTSD/cPTSD诊断,是在进行临床访谈时支持PTSD/cPTSD诊断的可靠措施。
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引用次数: 0
Patterns of mental health problems and resilience among immigrant and refugee adolescents: a latent profile analysis. 移民和难民青少年的心理健康问题和复原力模式:潜在剖面分析。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-03-27 DOI: 10.1080/20008066.2025.2479924
Sanni Aalto, Raija-Leena Punamäki, Mervi Vänskä, Reeta Kankaanpää, Tiina Turunen, Oskari Lahtinen, Ilse Derluyn, Caroline Spaas, Lucia De Haene, Signe Smith Jervelund, Morten Skovdal, Arnfinn J Andersen, Marianne Opaas, Fatumo Osman, Anna Sarkadi, Natalie Durbeej, Emma Soye, Kirsi Peltonen

Background: Immigrant and refugee adolescents often face traumatic experiences and are vulnerable to mental health problems, such as post-traumatic stress disorder (PTSD), anxiety and depression. Yet, they also show remarkable resilience in the face of these stressors. Research is still scarce on how both mental health problems and resilience dynamically interplay in immigrant and refugee adolescents' development.Objective: We aimed to identify latent profiles of immigrant and refugee adolescents' wellbeing, consisting of externalizing and internalizing symptoms, PTSD (intrusion and avoidance), and resilience, and analyse the demographic and contextual determinants of these profiles.Method: We employed cross-sectional survey data from the RefugeesWellSchool project for 1607 immigrant and refugee adolescents (mean age 15.3 years, SD 2.15, 42.3% girls) from six European countries: Belgium, Denmark, Finland, Norway, Sweden, and the United Kingdom. Latent profile analysis and three-step procedure with BCH weights were used to identify the wellbeing profiles and their determinants.Results: Results identified four adolescent wellbeing profiles: (1) Low symptoms (49.7%, n = 791); (2) High symptoms with intrusion (10.6%, n = 169); (3) Moderate symptoms (26.9%, n = 428); and (4) Resilient avoidant (12.8%, n = 203). Older participants, those with refugee background, shorter residence in the host country, more experiences of daily stressors or discrimination, or low family support were less likely to belong to the Low symptoms or Resilient avoidant groups (p ≤ .001).Conclusions: The profiles reflected distinct differentiation of intrusive and avoidance dimensions of the PTSD-symptoms. Intrusion clustered with high level of other mental health problems, whereas avoidance co-occurred with high resilience. Experiences related to immigration, stressors, and family support were crucial determinants of the wellbeing profile membership. Future interventions should utilize information obtained by person-centered studies to create better targeted and tailored support for immigrant and refugee adolescents.

背景:移民和难民青少年经常面临创伤经历,容易受到创伤后应激障碍(PTSD)、焦虑和抑郁等心理健康问题的影响。然而,面对这些压力,他们也表现出了非凡的弹性。在移民和难民青少年的发展中,心理健康问题和弹性如何动态相互作用的研究仍然很少。目的:我们旨在确定移民和难民青少年健康的潜在特征,包括外化和内化症状、创伤后应激障碍(入侵和回避)和复原力,并分析这些特征的人口统计学和环境决定因素。方法:我们采用来自“难民健康学校”项目的横断面调查数据,对来自比利时、丹麦、芬兰、挪威、瑞典和英国六个欧洲国家的1607名移民和难民青少年(平均年龄15.3岁,标准差2.15,女孩占42.3%)进行调查。使用潜在剖面分析和三步程序与BCH权重来确定健康概况及其决定因素。结果:结果确定了四种青少年健康状况:(1)低症状(49.7%,n = 791);(2)高症状伴侵入(10.6%,n = 169);(3)中度症状(26.9%,n = 428);(4)弹性回避型(12.8%,n = 203)。年龄较大、有难民背景、在东道国居住时间较短、日常压力源或歧视经历较多或家庭支持较低的参与者不太可能属于低症状或弹性回避组(p≤0.001)。结论:创伤后应激障碍症状在侵入性维度和回避性维度上有明显的差异。入侵与其他高水平的心理健康问题聚集在一起,而回避与高弹性同时发生。与移民、压力源和家庭支持相关的经历是健康概况会员资格的关键决定因素。未来的干预措施应利用以人为中心的研究获得的信息,为移民和难民青少年提供更有针对性和量身定制的支持。
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引用次数: 0
The pain of PTSD: integrating persistent or chronic pain within emotional processing theory of posttraumatic stress disorder. 创伤后应激障碍的疼痛:在创伤后应激障碍情绪加工理论中整合持续性或慢性疼痛。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-04-01 DOI: 10.1080/20008066.2025.2479923
Natalie Hellman, Stephanie M Haft, Anna Woodbury, Andrew M Sherrill, Sheila A M Rauch

Background: Posttraumatic stress disorder (PTSD) and chronic pain are devastating conditions that often co-occur. Current understanding of comorbid PTSD and chronic pain is limited, and treatment options are undereffective.Objective: This paper presents a theoretical basis for conceptualising chronic pain symptoms within Emotional Processing Theory (EPT), the foundation for Prolonged Exposure (PE), an effective treatment for PTSD. EPT conceptualises the development and treatment of PTSD using a trauma structure that strongly overlaps with pain's neurobiology.Method: This paper proposes a model of shared aetiology and treatment of comorbid PTSD and chronic pain, emphasising these shared neurobiological underpinnings. Discussion details how the comorbidity is maintained through parallel avoidance processes focused on: (1) trauma memories and reminders in PTSD preventing reduction of negative affect (extinction) and inhibitory learning, and (2) physical pain in chronic pain fuelling increased pain and reduced function.Results: A conceptualisation is presented on how PTSD and chronic pain symptomology can be addressed within the EPT framework, increasing the confidence of providers and patients while addressing an important gap in the literature. Finally, recommendations for providers using PE with patients with PTSD and pain are provided including a case example and treatment plan based on real patients.Conclusions: This model provides a clinically useful understanding of the underlying neurobiology for the co-occurrence of PTSD and chronic pain and offers direction for future research.

背景:创伤后应激障碍(PTSD)和慢性疼痛是经常同时发生的破坏性疾病。目前对创伤后应激障碍和慢性疼痛共病的认识有限,治疗方案也不够有效。目的:探讨情绪加工理论(EPT)中慢性疼痛症状概念化的理论基础,为PTSD的有效治疗方法延长暴露(PE)奠定基础。EPT将PTSD的发展和治疗概念化,使用与疼痛神经生物学强烈重叠的创伤结构。方法:本文提出了一个共同的病因和治疗模式的共病PTSD和慢性疼痛,强调这些共同的神经生物学基础。详细讨论了如何通过平行回避过程来维持共病,重点是:(1)创伤后应激障碍中的创伤记忆和提醒阻止了负面影响(消退)和抑制性学习的减少;(2)慢性疼痛中的身体疼痛加剧了疼痛和功能下降。结果:提出了在EPT框架内如何解决PTSD和慢性疼痛症状的概念化,增加了提供者和患者的信心,同时解决了文献中的一个重要空白。最后,针对创伤后应激障碍和疼痛患者的PE治疗提供了建议,包括一个案例和基于真实患者的治疗方案。结论:该模型对PTSD与慢性疼痛共存的潜在神经生物学机制提供了临床有用的认识,并为今后的研究提供了方向。
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引用次数: 0
Causal relationship between inflammatory cytokines and posttraumatic stress disorder: a Mendelian randomization study and potential mechanism analysis. 炎症细胞因子与创伤后应激障碍的因果关系:孟德尔随机研究和潜在机制分析。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-05-02 DOI: 10.1080/20008066.2025.2494480
Yingchong Li, Bangliang Xu, Zhitao Chen

Background: Post-traumatic stress disorder (PTSD) is a complex condition linked to inflammation. The causality between inflammatory cytokines and PTSD risk remains unclear.Methods: We conducted a bidirectional two-sample Mendelian randomization (MR) study using genome-wide association study (GWAS) data from 41 inflammatory cytokines and PTSD. Additional analyses included differential gene expression, protein-protein interaction, and functional enrichment to explore underlying mechanisms.Results: MR analysis indicated that higher levels of stem cell factor (SCF) and interleukin-4 (IL-4) are associated with a reduced risk of PTSD. Genes POGZ and LRIG2 were identified as mediators, implicated in the TGF-beta signalling pathway.Conclusion: Our findings suggest a protective role of certain cytokines against PTSD and highlight potential molecular mediators. This knowledge could inform future therapeutic strategies for PTSD.

背景:创伤后应激障碍(PTSD)是一种与炎症有关的复杂疾病。炎症细胞因子与PTSD风险之间的因果关系尚不清楚。方法:利用41种炎症因子与创伤后应激障碍的全基因组关联研究(GWAS)数据,进行了一项双向双样本孟德尔随机化(MR)研究。其他分析包括差异基因表达、蛋白蛋白相互作用和功能富集,以探索潜在的机制。结果:磁共振分析表明,较高水平的干细胞因子(SCF)和白细胞介素-4 (IL-4)与PTSD风险降低有关。基因POGZ和LRIG2被鉴定为介导tgf - β信号通路。结论:我们的研究结果提示了某些细胞因子对PTSD的保护作用,并强调了潜在的分子介质。这一知识可以为创伤后应激障碍的未来治疗策略提供信息。
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引用次数: 0
Subjective and objective sleep disturbances following trauma-focused treatment. 创伤性治疗后的主观和客观睡眠障碍。
IF 4.1 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-08-27 DOI: 10.1080/20008066.2025.2542044
Salomé Porten, Franziska Friedmann, Nikola Schoofs, Charlotte Barth, Kristina Meyer, Philip Santangelo, Ulrich Ebner-Priemer, Meike Müller-Engelmann, Regina Steil, Nikolaus Kleindienst, Frank Enning, Thomas Fydrich, Kathlen Priebe

Background: Most individuals with posttraumatic stress disorder (PTSD) report sleep disturbances. Yet, results on the impact of trauma-focused therapy on subjective and objective sleep disturbances are inconsistent.Objectives: This study conducted secondary analyses from a randomized controlled trial (RCT; German Clinical Trials Registration: DRKS00005578) to investigate changes in both subjective and objective sleep over the course of trauma-focused therapy and whether these changes differed for dialectical behaviour therapy for PTSD (DBT-PTSD) or cognitive processing therapy (CPT).Methods: Women with PTSD related to childhood abuse were randomized to receive DBT-PTSD or CPT. Sleep was assessed in n = 180 women using the Pittsburgh Sleep Quality Index (PSQI), sleep diaries, and actigraphy at baseline, 6 and 12 months into treatment, with sleep monitoring for 1 week at each assessment.Results: Subjective sleep disturbances improved significantly from pre- to post-treatment, reflected in better PSQI scores (d = 0.76), sleep quality (d = 0.69), and total sleep time (d = 0.11) in sleep diary entries with no differences between treatment groups. No significant changes were observed in actigraphy measures. In total, 76% of participants still met the clinical cut-off of 5 on the PSQI, indicating clinically significant subjective sleep disturbances.Conclusions: PTSD treatments were linked to improvements in subjective sleep quality, but objective sleep measures remained unaffected. A high percentage of participants with persistent clinical sleep disturbances after treatment highlight the need for further research on the efficacy of PTSD treatments on sleep disturbances. To reduce the burden of sleep disturbances, sleep-specific treatment components may need to be added to trauma-focused treatments.

背景:大多数创伤后应激障碍(PTSD)患者报告睡眠障碍。然而,创伤治疗对主观和客观睡眠障碍的影响结果并不一致。目的:本研究对一项随机对照试验(RCT;德国临床试验注册号:DRKS00005578)进行了二次分析,以调查创伤集中治疗过程中主观和客观睡眠的变化,以及这些变化是否在辩证行为治疗PTSD (DBT-PTSD)或认知加工治疗(CPT)中有所不同。方法:将儿童期受虐相关的PTSD女性随机分为DBT-PTSD或CPT两组。使用匹兹堡睡眠质量指数(PSQI)、睡眠日记和活动记录仪对n = 180名女性的睡眠进行评估,在治疗6个月和12个月时进行基线评估,每次评估时进行1周的睡眠监测。结果:主观睡眠障碍从治疗前到治疗后显著改善,反映在睡眠日记条目中更好的PSQI评分(d = 0.76),睡眠质量(d = 0.69)和总睡眠时间(d = 0.11),治疗组之间无差异。活动描记术未见明显变化。总的来说,76%的参与者在PSQI上仍然达到了5分的临床临界值,这表明临床上存在明显的主观睡眠障碍。结论:创伤后应激障碍治疗与主观睡眠质量的改善有关,但客观睡眠测量不受影响。高百分比的参与者在治疗后出现持续的临床睡眠障碍,这表明需要进一步研究创伤后应激障碍治疗对睡眠障碍的疗效。为了减轻睡眠障碍的负担,可能需要在以创伤为重点的治疗中增加针对睡眠的治疗成分。
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引用次数: 0
'Stay with the body': facilitating integrative silence in community-based sexual trauma care. “与身体在一起”:促进以社区为基础的性创伤护理中的综合沉默。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-06-17 DOI: 10.1080/20008066.2025.2510020
Leona Morgan, Sarojini Nadar, Ines Keygnaert

Background: Research has demonstrated that the verbal disclosure for adult victims of childhood sexual trauma (CST) presents significant challenges and seldom provides comprehensive trauma integration. Limited psychosocial support and specialist trauma care particularly in marginalised communities, can further exacerbate the non-disclosure of CST. Although various intervention models for adult victims of CST exist, the potential of facilitating integrative silence as part of community centred integrative trauma informed care (ITIC), remains under-explored.Objective: The objective of this article, is to document how facilitating spaces of integrative silence in a therapeutic context, shifts embodied trauma awareness, comprehensive trauma realisation and trauma integration for adult victims of CST from intergenerational marginalised contexts.Methods: Through participatory action research (PAR), framed in de-colonial feminist community praxis with 13 women aged 21-62, the first author as therapist-researcher facilitated audio-visual recorded semi-structured interviews (n = 13) and integrative trauma informed care (ITIC) follow-up sessions (n = 60) to assess the value of the spoken, unspoken and silence in trauma care. Inductive reflexive thematic analysis and a multistage recursive coding process of verbatim transcriptions, were used to identify embodied trauma awareness before, during, and after periods of silence.Results: The de-colonial, feminist framing for community centred ITIC enhanced participant-specific embodied awareness, establishing a safe space for self-reflection. Contextual sensitivity and careful attention to the therapeutic environment were paramount. The facilitation of non-verbal expression empowered participants to explore alternatives to normative, essentialist and religious narratives that often stigmatise trauma responses. This approach enabled participants to reclaim a sense of agency, improving self-regulation and self-care.Conclusion: This study highlights the potential of integrative silence in community based therapeutic contexts. Future research could explore the role of integrative silence in treating various forms of trauma in different cultural and geographic settings and its integration with other therapeutic modalities to enhance culturally sensitive mental health care.

背景:研究表明,儿童性创伤成年受害者的言语披露存在很大的挑战,而且很少提供全面的创伤整合。有限的社会心理支持和专业创伤护理,特别是在边缘化社区,可能进一步加剧不披露CST。尽管存在针对CST成年受害者的各种干预模式,但作为以社区为中心的综合创伤知情护理(ITIC)的一部分,促进综合沉默的潜力仍未得到充分探索。目的:本文的目的是记录在治疗背景下促进整合沉默的空间,如何从代际边缘环境中转变CST成年受害者的具体创伤意识,全面创伤实现和创伤整合。方法:通过参与行动研究(PAR),在去殖民女性主义社区实践框架下,以13名年龄在21-62岁的女性为研究对象,第一作者作为治疗师-研究者促进了视听记录的半结构化访谈(n = 13)和综合创伤知情护理(ITIC)随访会议(n = 60),以评估创伤护理中口头、非口头和沉默的价值。归纳反身主题分析和逐字转录的多阶段递归编码过程,用于识别在沉默之前,期间和之后的具体创伤意识。结果:以社区为中心的ITIC的去殖民、女权主义框架增强了参与者的具体体现意识,为自我反思建立了一个安全的空间。情境敏感性和对治疗环境的仔细关注是至关重要的。非语言表达的便利使参与者能够探索规范性、本质主义和宗教叙事的替代方案,这些叙事往往会使创伤反应蒙上污名。这种方法使参与者重拾能动性,提高自我调节和自我照顾。结论:本研究强调了在基于社区的治疗环境中整合沉默的潜力。未来的研究可以探索整合沉默在不同文化和地理环境中治疗各种形式创伤的作用,并与其他治疗方式相结合,以增强文化敏感性的心理卫生保健。
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引用次数: 0
The influence of identity-oriented psychotrauma therapy on Hashimoto disease activity: a randomised controlled trial. 身份导向心理创伤治疗对桥本病活动性的影响:一项随机对照试验。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-06-26 DOI: 10.1080/20008066.2025.2520636
Maria-Magdalena Macarenco, Cristian Opariuc-Dan, Teodora Georgescu

ABSTRACTBackground: Childhood adversity and trauma have been linked to altered thyroid function and hypothyroidism, yet few randomised controlled trials (RCTs) have examined the effectiveness of trauma-focused psychological interventions in patients with Hashimoto's thyroiditis (HT).Objective: This study aimed to evaluate the effectiveness of Identity-Oriented Psychotrauma Therapy (IOPT) in adults with HT, focusing on both immunological and psychological outcomes.Method: This parallel-group RCT randomised 70 adults with HT (93.94% women; age 25-57) to receive treatment as usual (TAU) or TAU plus IOPT. The intervention comprised 10 bimonthly group sessions, one session every two weeks. Outcomes included thyroid peroxidase (TPO-ab) and thyroglobulin (TG-ab) antibodies, along with depression, anxiety, stress, dissociation, alexithymia, and anger, assessed at baseline, post-treatment, and 3-month follow-up. A series of 2-way mixed-model ANOVAs and Bonferroni-corrected post-hoc tests were used. Missing data due to attrition - particularly in the control group (37%) - were addressed via multiple imputation, and sensitivity analyses were conducted to test robustness.Results: Initial analyses suggested that IOPT significantly reduced TPO-ab levels compared to TAU (p < .001), with effects maintained at follow-up (p = .01); however, these effects were not replicated in complete case analysis. IOPT led to significant improvements in dissociation (p = .03), alexithymia (p < .001), depression (p < .001), anxiety (p < .001), stress (p = .015), state anger (p = .009), anger-in (p = .009), and quality of life (p = .042) at follow-up.Conclusion: These preliminary findings suggest that IOPT, when added to standard medical care, may offer psychological benefits for HT patients and could potentially influence immunological outcomes. However, given the attrition-related sensitivity of some results, further replication in larger, well-retained samples is necessary before drawing definitive conclusions.Trial registration: ClinicalTrials.gov identifier: NCT04600349.

摘要背景:童年逆境和创伤与甲状腺功能改变和甲状腺功能减退有关,但很少有随机对照试验(RCTs)研究以创伤为重点的心理干预对桥本甲状腺炎(HT)患者的有效性。目的:本研究旨在评估身份导向心理创伤治疗(IOPT)在成人HT患者中的有效性,重点关注免疫和心理结果。方法:该平行组RCT随机选取70例成人HT患者(93.94%为女性;年龄25-57岁)接受常规治疗(TAU)或TAU + IOPT。干预包括10个双月小组会议,每两周一次。结果包括甲状腺过氧化物酶(TPO-ab)和甲状腺球蛋白(TG-ab)抗体,以及抑郁、焦虑、压力、解离、叙情障碍和愤怒,在基线、治疗后和3个月随访时进行评估。采用了一系列双向混合模型方差分析和bonferroni校正的事后检验。由于磨耗导致的数据缺失——特别是在对照组(37%)——通过多重输入处理,并进行敏感性分析以检验稳健性。结果:初步分析表明,与TAU相比,IOPT显著降低TPO-ab水平(p p = 0.01);然而,这些效果并没有在完整的病例分析中得到证实。IOPT在分离(p = .03)、说情障碍(p = .015)、状态愤怒(p = .009)、愤怒(p = .009)和生活质量(p = .042)方面有显著改善。结论:这些初步研究结果表明,当IOPT加入标准医疗护理时,可能为HT患者提供心理益处,并可能影响免疫结果。然而,考虑到一些结果与磨损相关的敏感性,在得出明确的结论之前,需要在更大、保留良好的样本中进一步复制。试验注册:ClinicalTrials.gov标识符:NCT04600349。
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引用次数: 0
Mind the gap: a nested randomised pilot study of culturally inclusive, internet-delivered prolonged exposure for PTSD among immigrants. 注意差距:一项嵌套的随机试点研究,研究文化包容性,移民中互联网提供的创伤后应激障碍的长期暴露。
IF 4.2 2区 医学 Q1 PSYCHIATRY Pub Date : 2025-12-01 Epub Date: 2025-06-30 DOI: 10.1080/20008066.2025.2520637
Olof Molander, Karoline Kolaas, Nitya Jayaram-Lindström, Moa Pontén, Josefin Särnholm, Maria Bragesjö

Background: PTSD is disproportionately prevalent among immigrants in Sweden, yet access to evidence-based treatments remains limited, especially for those facing language barriers. Internet-delivered prolonged exposure (I-PE) may help overcome these challenges, but its feasibility and effectiveness in diverse populations remain underexplored.Objective: This study evaluated the feasibility, acceptability, and preliminary effects of a culturally inclusive, therapist-guided I-PE programme in easy-to-read English for immigrants with PTSD.Method: A nested pilot study within an ongoing RCT randomised 30 participants to I-PE or a waitlist control. The intervention incorporated simplified language, diverse visual representations, and a user-friendly platform. Feasibility outcomes included recruitment, adherence, and retention. Acceptability was assessed through satisfaction, adverse effects, and cultural appropriateness, while preliminary efficacy was evaluated via PTSD symptom severity and secondary measures of depression.Results: Recruitment was completed in six weeks, with moderate to high retention. Adherence was strong, with 63% completing at least five I-PE modules. Participants rated the intervention as highly acceptable, with no major cultural barriers. The easy-to-read English format was well received, with no reported linguistic accessibility issues. No serious adverse events were reported. PTSD symptoms significantly decreased in the I-PE group (Cohen's d = 1.45; p < .001), with moderate reductions in depression (Cohen's d = .80; p < .01).Conclusions: The findings support the feasibility and acceptability of a culturally inclusive, therapist-guided I-PE programme for PTSD among immigrants. The participants perceived the I-PE as helpful, trustworthy, and easy to use, with no suggestions for further cultural modifications or reports of cultural inappropriateness. However, the sample's relatively high English proficiency and education may limit generalizability to other groups who have migrated to Sweden. A full-scale randomised controlled trial is needed to assess clinical and cost-effectiveness, as well as implementation across more diverse immigrant populations.Trial registration: ClinicalTrials.gov identifier: NCT06193161..

背景:PTSD在瑞典的移民中非常普遍,但获得循证治疗的机会仍然有限,特别是对那些有语言障碍的人。互联网提供的长时间暴露(I-PE)可能有助于克服这些挑战,但其在不同人群中的可行性和有效性仍未得到充分探索。目的:本研究评估文化包容性、治疗师指导的易读英语I-PE项目对创伤后应激障碍移民的可行性、可接受性和初步效果。方法:在一项正在进行的随机对照试验中,随机选取30名参与者进行I-PE或候补对照。干预措施包括简化的语言,多样化的视觉表现和用户友好的平台。可行性结果包括招募、依从性和留任。可接受性通过满意度、不良反应和文化适宜性来评估,而初步疗效通过PTSD症状严重程度和次要抑郁指标来评估。结果:招募在6周内完成,有中高保留率。依从性很强,63%的患者完成了至少5个I-PE模块。参与者认为干预是高度可接受的,没有主要的文化障碍。易于阅读的英文格式很受欢迎,没有报告语言可访问性问题。无严重不良事件报告。I-PE组PTSD症状显著减轻(Cohen’s d = 1.45;p d = 0.80;结论:研究结果支持了文化包容性、治疗师指导的移民PTSD I-PE项目的可行性和可接受性。参与者认为I-PE是有用的,值得信赖的,易于使用的,没有建议进一步的文化修改或文化不适当的报告。然而,样本的相对较高的英语熟练程度和教育程度可能限制了对其他移民到瑞典的群体的推广。需要一项全面的随机对照试验来评估临床和成本效益,以及在更多样化的移民人群中实施。试验注册:ClinicalTrials.gov标识符:NCT06193161。
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European Journal of Psychotraumatology
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