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The utility of the prehospital shock index, age shock index, and modified shock index for predicting hypofibrinogenaemia in trauma patients: an observational retrospective study. 院前休克指数、年龄休克指数和改良休克指数对预测创伤患者低纤维蛋白原血症的实用性:一项观察性回顾研究。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-07 DOI: 10.1007/s00068-024-02603-x
Jihwan Moon, Sungwook Park

Purpose: Reduced fibrinogen levels are associated with worse outcomes in bleeding trauma patients. The purpose of this study was to evaluate the potential of the prehospital shock index (SI) and its derivatives, the age shock index (aSI) and the modified shock index (mSI), as predictors of hypofibrinogenaemia in trauma patients.

Methods: This retrospective study included 2383 patients who presented to a regional trauma center. We reviewed the plasma fibrinogen levels upon admission to the trauma center and patients were divided into two groups: the hypofibrinogenaemia group and the normal group. The predictive performances of the SI, aSI, and mSI were assessed by the area under the receiver operating characteristic curve (AUC).

Results: Of the 2383 patients, 235 (9.9%) had hypofibrinogenaemia. Patients with hypofibrinogenaemia were more likely to receive transfusions within 4 h and had significantly greater in-hospital mortality than patients with normal fibrinogen levels. The AUCs of prehospital SI, prehospital aSI, and prehospital mSI for the prediction of hypofibrinogenaemia were 0.75 (95% confidence interval [CI] 0.73-0.77), 0.70 (95% CI 0.68-0.72), and 0.75 (95% CI 0.73-0.77), respectively.

Conclusion: Prehospital SI and prehospital mSI demonstrated moderate performance for identifying trauma patients with hypofibrinogenaemia. The prehospital aSI had poor predictive performance. In the prehospital setting, the use of prehospital SI or prehospital mSI as the sole predictor of hypofibrinogenaemia in trauma patients is not recommended.

目的:纤维蛋白原水平降低与出血创伤患者的预后恶化有关。本研究旨在评估院前休克指数(SI)及其衍生物、年龄休克指数(aSI)和修正休克指数(mSI)作为创伤患者低纤维蛋白原血症预测指标的潜力:这项回顾性研究包括 2383 名在地区创伤中心就诊的患者。我们检查了患者入院时的血浆纤维蛋白原水平,并将患者分为两组:低纤维蛋白原血症组和正常组。我们用接收器操作特征曲线下面积(AUC)评估了SI、aSI和mSI的预测性能:在 2383 名患者中,235 人(9.9%)患有低纤维蛋白原血症。与纤维蛋白原水平正常的患者相比,低纤维蛋白原血症患者更有可能在4小时内接受输血,其院内死亡率也明显更高。院前 SI、院前 aSI 和院前 mSI 预测低纤维蛋白原血症的 AUC 分别为 0.75(95% 置信区间 [CI] 0.73-0.77)、0.70(95% CI 0.68-0.72)和 0.75(95% CI 0.73-0.77):结论:院前 SI 和院前 mSI 在识别低纤维蛋白原血症的创伤患者方面表现一般。院前 aSI 的预测性能较差。在院前环境中,不建议使用院前 SI 或院前 mSI 作为创伤患者低纤维蛋白原血症的唯一预测指标。
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引用次数: 0
Association of trauma classifications to long-term outcome in blunt trauma patients. 创伤分类与钝性创伤患者长期预后的关系。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-07 DOI: 10.1007/s00068-024-02606-8
Joonas Kuorikoski, Mikko Heinänen, Tuomas Brinck, Tim Söderlund

Purpose: The impact of major trauma is long lasting. Although polytrauma patients are currently identified with the Berlin polytrauma criteria, data on long-term outcomes are not available. In this study, we evaluated the association of trauma classification with long-term outcome in blunt-trauma patients.

Methods: A trauma registry of a level I trauma centre was used for patient identification from 1.1.2006 to 31.12.2015. Patients were grouped as follows: (1) all severely injured trauma patients; (2) all severely injured polytrauma patients; 2a) severely injured patients with AIS ≥ 3 on two different body regions (Berlin-); 2b) severely injured patients with polytrauma and a physiological criterion (Berlin+); and (3) a non-polytrauma group. Kaplan-Meier survival analysis was performed to estimate differences in mortality between different groups.

Results: We identified 3359 trauma patients for this study. Non-polytrauma was the largest group (2380 [70.9%] patients). A total of 500 (14.9%) patients fulfilled the criteria for Berlin + definition, leaving 479 (14.3%) polytrauma patients in Berlin- group. Berlin + patients had the highest short-term mortality compared with other groups, although the difference in cumulative mortality gradually plateaued compared with the non-polytrauma patient group; at the end of the 10-year follow up, the non-polytrauma group had the greatest mortality due to the high number of patients with traumatic brain injury (TBI).

Conclusion: Excess mortality of polytrauma patients by Berlin definition occurs in the early phase (30-day mortality) and late deaths are rare. TBI causes high early mortality followed by increased long-term mortality.

目的:重大创伤的影响是长期的。尽管目前根据柏林多发性创伤标准对多发性创伤患者进行了鉴定,但却没有关于长期预后的数据。在这项研究中,我们评估了创伤分类与钝性创伤患者长期预后的关系:方法:2006 年 1 月 1 日至 2015 年 12 月 31 日期间,一家一级创伤中心的创伤登记处对患者进行了身份识别。患者分组如下(1)所有严重创伤患者;(2)所有严重多发创伤患者;2a)两个不同身体区域AIS≥3的严重创伤患者(柏林-);2b)多发创伤且符合生理标准的严重创伤患者(柏林+);(3)非多发创伤组。我们进行了卡普兰-梅耶生存分析,以估计不同组别之间死亡率的差异:我们为这项研究确定了 3359 名创伤患者。非多发性创伤是最大的组别(2380 名[70.9%]患者)。共有 500 名(14.9%)患者符合 "柏林+"定义标准,剩下的 479 名(14.3%)多发性创伤患者属于 "柏林-"组。与其他组别相比,"柏林+"组患者的短期死亡率最高,但与非多发性创伤患者组相比,累积死亡率的差异逐渐趋于平稳;在10年随访结束时,非多发性创伤组的死亡率最高,原因是有大量患者患有创伤性脑损伤(TBI):结论:根据柏林的定义,多发性创伤患者的高死亡率发生在早期阶段(30 天死亡率),晚期死亡很少见。创伤性脑损伤导致早期死亡率高,随后长期死亡率增加。
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引用次数: 0
Lack of standardisation in the management of complex tibial plateau fractures: a multicentre experience. 复杂胫骨平台骨折治疗缺乏标准化:多中心经验。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-02 DOI: 10.1007/s00068-024-02616-6
Christina Hörmandinger, David Bitschi, Daniel P Berthold, Claas Neidlein, Lennart Schroeder, Julius Watrinet, Robert Pätzold, Wolfgang Böcker, Boris Michael Holzapfel, Julian Fürmetz, Markus Bormann

Objective: In recent years, the trauma mechanisms and fracture types in tibial plateau fractures (TPF) have changed. At the same time, treatment strategies have expanded with the establishment of new classification systems, extension of diagnostics and surgical strategies. Evidence-based recommendations for treatment strategies are rare. The aim of this study is to assess the extent of standardization in the treatment of complex TPF.

Material and methods: For the study, specialists in trauma surgery/orthopaedics were presented thin-slice CT data sets of three complex TPFs including 3D reconstructions. A standardized questionnaire on fracture morphology and planned treatment strategy was then completed.

Results: A total of 23 surgeons from 7 hospitals (Trauma center levels I-III) were included. All three fractures were most frequently classified as Schatzker type V (fracture I: 52.2%, II: 56.5%, III: 60%). Averaged over all three fractures, 55% of the respondents chose the same patient positioning. The combination of a posteromedial and anterolateral approach was the most frequently chosen approach at 42.7%. Double plating was favored for the surgical treatment of all fractures (70.7%). Preoperative MRI, extended approaches and intraoperative fraturoscopy were significantly more common in level I trauma centres.

Conclusion: There are major differences in the management of complex TPF. 360° treatment is carried out in all departments regardless of the level of care, but without further standardization in terms of preoperative imaging, classification, initial treatment, approach, fixation and intraoperative imaging. There are major differences within the departments with different level of care.

目的:近年来,胫骨平台骨折(TPF)的创伤机制和骨折类型发生了变化。与此同时,随着新分类系统的建立、诊断和手术策略的扩展,治疗策略也在不断扩展。以证据为基础的治疗策略建议并不多见。本研究旨在评估复杂 TPF 治疗的标准化程度:研究向创伤外科/骨科专家提供了三例复杂 TPF 的薄片 CT 数据集,包括三维重建。然后填写一份关于骨折形态和计划治疗策略的标准化问卷:结果:共有来自 7 家医院(一级至三级创伤中心)的 23 名外科医生参与了调查。所有三种骨折最常被归类为 Schatzker V 型(I 型骨折:52.2%;II 型骨折:56.5%;III 型骨折:60%)。对所有三种骨折进行平均,55%的受访者选择了相同的患者体位。后内侧和前外侧联合入路是最常见的入路,占 42.7%。所有骨折的手术治疗均采用双层钢板固定(70.7%)。在一级创伤中心,术前核磁共振成像、扩展入路和术中骨膜镜检查明显更常见:结论:复杂 TPF 的治疗存在很大差异。结论:复杂 TPF 的治疗存在很大差异。所有科室都在进行 360° 治疗,无论医疗水平如何,但在术前成像、分类、初始治疗、方法、固定和术中成像方面没有进一步标准化。不同护理级别的科室之间存在很大差异。
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引用次数: 0
41st Meeting of the Pediatric Section of the German Society of Trauma Surgeons : Kongress für Kinder in Orthopädie und Unfallchirurgie 2023 41. Jahrestagung der SKT 36. Jahrestagung der VKO 19. - 20. Mai 2023 Garmisch-Partenkirchen. 德国创伤外科医师学会儿科分会第 41 届会议:2023 年儿童矫形外科大会(Kongress für Kinder in Orthopädie und Unfallchirurgie 2023 年第 41 届德国创伤外科医师学会年会(SKT)第 36 届德国创伤外科医师学会年会(VKO)2023 年 5 月 19 - 20 日,加米施-帕滕基兴。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-01 DOI: 10.1007/s00068-024-02490-2
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引用次数: 0
Penetrating trauma on the rise- nine-year trends of severe trauma in Sweden. 穿透性创伤呈上升趋势--瑞典严重创伤的九年趋势。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-07-30 DOI: 10.1007/s00068-024-02601-z
Lina Holmberg, Kevin Mani, Fredrik Linder, Anders Wanhainen, Carl Magnus Wahlgren, Håkan Andréasson

Purpose: Sweden has an established trauma system involving national trauma criteria and the Swedish trauma registry (SweTrau), since over a decade. Meanwhile, the injury panorama has evolved, with an increase in gang-related violence in the Swedish community. In this study, we aimed to investigate long-term trends in mortality, management and trauma type in two major Swedish trauma centers over a nine-year period.

Methods: All trauma patients with a New Injury Score (NISS) > 15 or a Trauma Alert (TA) call during 2013-2021 were identified in the participating centers' SweTrau registries. Data were analysed regarding mortality, proportion of emergency interventions, intensive care unit (ICU) admissions, mechanism of injury and type of trauma (penetrating or blunt). To assess trends, Chi-Squared test for trend and JoinPoint regression method were used.

Results: A total of 10,587 patients were included in the study. Mortality remained unchanged over time in patients with NISS > 15 (10.0-10.9%, p = 0.963) but increased in patients with a TA and NISS < 15 (1.3-2.7%, p = 0.005). For NISS > 15, the proportion undergoing emergency interventions was stable (53.9%-48.8%, p = 0.297) while ICU admissions declined (62.1%-45.7%, p < 0.001). Penetrating trauma increased (12.4-19.6%, p < 0.001), including knife (10.0-15.7%, p < 0.001) and gunshot wounds (2.3-3.8%, p < 0.001), whereas accidents involving motorcycles (8.8%-7.0%, p = 0.004) and pedestrians (5.3%-2.2%, p < 0.001) decreased. Assaults (both penetrating and blunt) increased from 14.7 to 21.4% (p < 0.001).

Conclusions: In this trend analysis at two major Swedish trauma centers during 2013-2021, penetrating trauma increased with over 50% while traffic injuries decreased. The rise in mortality in patients with a TA and NISS < 15 is concerning and requires further evaluation, as do the reduction in ICU admissions.

目的:十多年来,瑞典建立了一套创伤系统,其中包括国家创伤标准和瑞典创伤登记处(SweTrau)。与此同时,随着瑞典社会中与帮派有关的暴力事件的增加,受伤情况也发生了变化。在这项研究中,我们旨在调查瑞典两大创伤中心九年来在死亡率、管理和创伤类型方面的长期趋势:方法:在参与中心的 SweTrau 登记簿中识别了 2013-2021 年期间新伤评分 (NISS) > 15 或接到创伤警报 (TA) 呼叫的所有创伤患者。分析的数据涉及死亡率、紧急干预比例、重症监护室 (ICU) 入住率、受伤机制和创伤类型(穿透性或钝性)。为了评估趋势,采用了Chi-Squared趋势检验法和JoinPoint回归法:研究共纳入了 10,587 名患者。随着时间的推移,NISS大于15的患者死亡率保持不变(10.0%-10.9%,p = 0.963),但TA和NISS为15的患者死亡率有所上升,接受急诊干预的比例保持稳定(53.9%-48.8%,p = 0.297),而入住重症监护室的比例有所下降(62.1%-45.7%,p 结论:在瑞典两大医院的这项趋势分析中,NISS大于15的患者死亡率保持不变(10.0%-10.9%,p = 0.963),但TA和NISS为15的患者死亡率有所上升:2013-2021年期间,瑞典两大创伤中心的趋势分析显示,穿透性创伤增加了50%以上,而交通事故伤害则有所减少。TA和NISS患者的死亡率上升
{"title":"Penetrating trauma on the rise- nine-year trends of severe trauma in Sweden.","authors":"Lina Holmberg, Kevin Mani, Fredrik Linder, Anders Wanhainen, Carl Magnus Wahlgren, Håkan Andréasson","doi":"10.1007/s00068-024-02601-z","DOIUrl":"https://doi.org/10.1007/s00068-024-02601-z","url":null,"abstract":"<p><strong>Purpose: </strong>Sweden has an established trauma system involving national trauma criteria and the Swedish trauma registry (SweTrau), since over a decade. Meanwhile, the injury panorama has evolved, with an increase in gang-related violence in the Swedish community. In this study, we aimed to investigate long-term trends in mortality, management and trauma type in two major Swedish trauma centers over a nine-year period.</p><p><strong>Methods: </strong>All trauma patients with a New Injury Score (NISS) > 15 or a Trauma Alert (TA) call during 2013-2021 were identified in the participating centers' SweTrau registries. Data were analysed regarding mortality, proportion of emergency interventions, intensive care unit (ICU) admissions, mechanism of injury and type of trauma (penetrating or blunt). To assess trends, Chi-Squared test for trend and JoinPoint regression method were used.</p><p><strong>Results: </strong>A total of 10,587 patients were included in the study. Mortality remained unchanged over time in patients with NISS > 15 (10.0-10.9%, p = 0.963) but increased in patients with a TA and NISS < 15 (1.3-2.7%, p = 0.005). For NISS > 15, the proportion undergoing emergency interventions was stable (53.9%-48.8%, p = 0.297) while ICU admissions declined (62.1%-45.7%, p < 0.001). Penetrating trauma increased (12.4-19.6%, p < 0.001), including knife (10.0-15.7%, p < 0.001) and gunshot wounds (2.3-3.8%, p < 0.001), whereas accidents involving motorcycles (8.8%-7.0%, p = 0.004) and pedestrians (5.3%-2.2%, p < 0.001) decreased. Assaults (both penetrating and blunt) increased from 14.7 to 21.4% (p < 0.001).</p><p><strong>Conclusions: </strong>In this trend analysis at two major Swedish trauma centers during 2013-2021, penetrating trauma increased with over 50% while traffic injuries decreased. The rise in mortality in patients with a TA and NISS < 15 is concerning and requires further evaluation, as do the reduction in ICU admissions.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prognosis of major trauma in patients older than 85 years admitted to the ICU, a registry-based study. 重症监护室收治的 85 岁以上老年人重大创伤的预后,一项基于登记的研究。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-07-30 DOI: 10.1007/s00068-024-02622-8
Vincent Legros, Benjamin Picard, Jean Pasqueron, Lukshe Kanagaratnam, Delphine Garrigue, Emmanuel Rozenberg, Paul Mandrillon, Julien Pottecher, Pierre-Antoine Seube-Remy, Thomas Vettese, Jean-Luc Hanouz, Pierre Gosset, Benjamin Popoff, Mathieu Willig, Benjamin Cohen, Fanny Bounes, Paer Selim Abback

Background: The aging population in France and Western Europe is on the rise, particularly among individuals aged 65 years and older. Although older adults are susceptible to traumatic injuries, they constitute a minority of trauma center admissions especially those aged 85 and above. The aim of our study was to investigate the prognostic factors for mortality among the older old population (aged 85 years and above) managed in ICU of Traumabase group trauma centers.

Methods: This retrospective observational cohort study, conducted from 2013 to 2022, analyzed all severely injured older patients (aged ≥ 85 years) managed in 14 ICU trauma centers enrolled in the Traumabase registry. The study examined sociodemographic, clinical, and outcome variables. Frailty was assessed using the Clinical Frailty Scale.

Results: Among the 365 older trauma patients, 190 (52.1%) were classified as non-frail (CFS 1-3), 80 (21.9%) as pre-frail (CFS 4,5), and 95 (26%) as frail (CFS 6-9). Falls were the most common mechanism of injury. High mortality rates were observed, with 43.5% ICU mortality and 45.5% mortality at day 30. Factors most associated with ICU mortality included traumatic brain injury (CGS < 13), pre-hospital micromethod hemoglobin < 13 and severity of injury (ISS > 16).

Conclusion: Factors such as traumatic brain injury and severe hemorrhage (micromethod hemoglobin < 13) and ISS > 16 are associated with ICU mortality in in patients older than 85 years trauma patient. Early geriatric intervention is crucial for optimizing outcomes in this vulnerable population.

背景:法国和西欧的老龄化人口不断增加,尤其是 65 岁及以上的老年人。虽然老年人很容易受到外伤,但他们在创伤中心收治的患者中只占少数,尤其是 85 岁及以上的老年人。我们的研究旨在调查在创伤中心重症监护室接受治疗的老年患者(85 岁及以上)的预后死亡因素:这项回顾性观察队列研究于 2013 年至 2022 年进行,分析了创伤数据库注册的 14 家重症监护室创伤中心收治的所有老年重伤患者(年龄≥ 85 岁)。研究考察了社会人口学、临床和结果变量。采用临床虚弱量表对虚弱程度进行评估:在 365 名老年创伤患者中,190 人(52.1%)被归类为非虚弱(CFS 1-3),80 人(21.9%)被归类为前期虚弱(CFS 4、5),95 人(26%)被归类为虚弱(CFS 6-9)。跌倒是最常见的受伤机制。观察到的死亡率很高,重症监护室死亡率为 43.5%,第 30 天死亡率为 45.5%。与重症监护室死亡率最相关的因素包括脑外伤(CGS 16):结论:脑外伤和严重出血(微量血红蛋白 16)等因素与 85 岁以上外伤患者的 ICU 死亡率有关。早期老年干预对于优化这一弱势群体的治疗效果至关重要。
{"title":"Prognosis of major trauma in patients older than 85 years admitted to the ICU, a registry-based study.","authors":"Vincent Legros, Benjamin Picard, Jean Pasqueron, Lukshe Kanagaratnam, Delphine Garrigue, Emmanuel Rozenberg, Paul Mandrillon, Julien Pottecher, Pierre-Antoine Seube-Remy, Thomas Vettese, Jean-Luc Hanouz, Pierre Gosset, Benjamin Popoff, Mathieu Willig, Benjamin Cohen, Fanny Bounes, Paer Selim Abback","doi":"10.1007/s00068-024-02622-8","DOIUrl":"https://doi.org/10.1007/s00068-024-02622-8","url":null,"abstract":"<p><strong>Background: </strong>The aging population in France and Western Europe is on the rise, particularly among individuals aged 65 years and older. Although older adults are susceptible to traumatic injuries, they constitute a minority of trauma center admissions especially those aged 85 and above. The aim of our study was to investigate the prognostic factors for mortality among the older old population (aged 85 years and above) managed in ICU of Traumabase group trauma centers.</p><p><strong>Methods: </strong>This retrospective observational cohort study, conducted from 2013 to 2022, analyzed all severely injured older patients (aged ≥ 85 years) managed in 14 ICU trauma centers enrolled in the Traumabase registry. The study examined sociodemographic, clinical, and outcome variables. Frailty was assessed using the Clinical Frailty Scale.</p><p><strong>Results: </strong>Among the 365 older trauma patients, 190 (52.1%) were classified as non-frail (CFS 1-3), 80 (21.9%) as pre-frail (CFS 4,5), and 95 (26%) as frail (CFS 6-9). Falls were the most common mechanism of injury. High mortality rates were observed, with 43.5% ICU mortality and 45.5% mortality at day 30. Factors most associated with ICU mortality included traumatic brain injury (CGS < 13), pre-hospital micromethod hemoglobin < 13 and severity of injury (ISS > 16).</p><p><strong>Conclusion: </strong>Factors such as traumatic brain injury and severe hemorrhage (micromethod hemoglobin < 13) and ISS > 16 are associated with ICU mortality in in patients older than 85 years trauma patient. Early geriatric intervention is crucial for optimizing outcomes in this vulnerable population.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing outcomes in traumatic brain injury: Helsinki score versus Glasgow coma scale. 评估创伤性脑损伤的结果:赫尔辛基评分与格拉斯哥昏迷量表。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-07-25 DOI: 10.1007/s00068-024-02604-w
Fares Komboz, Hiba Douja Chehade, Bilal Al Saffar, Dorothee Mielke, Veit Rohde, Tammam Abboud

Background: The precision of assessment and prognosis in traumatic brain injury (TBI) is paramount for effective triage and informed therapeutic strategies. While the Glasgow Coma Scale (GCS) remains the cornerstone for TBI evaluation, it overlooks critical primary imaging findings. The Helsinki Score (HS), a novel tool designed to incorporate radiological data, offers a promising approach to predicting TBI outcomes. This study aims to evaluate the prognostic efficacy of HS in comparison to GCS across a substantial TBI patient cohort.

Methods: This retrospective study encompassed TBI patients treated at our institution between 2008 and 2019, specifically those with an admission GCS of 14 or lower. We assessed both the initial GCS and the HS derived from primary CT scans. Key outcome metrics included the Glasgow Outcome Scale (GOS) and mortality rates at hospital discharge and at 6 and 12-month intervals post-discharge. Predictive performances of GCS and HS were analyzed through Receiver Operating Characteristic (ROC) curves and Kendall tau-b correlation coefficients against each outcome.

Results: The study included 544 patients, with an average age of 62.2 ± 21.5 years, median initial GCS of 14, and a median HS of 3. The mortality rate at discharge stood at 8.6%, with a median GOS of 4. Both GCS and HS demonstrated significant correlations with mortality and GOS outcomes (p < 0.05). Notably, HS showed a markedly superior correlation with mortality (τb = 0.36) compared to GCS (τb = -0.11) and with GOS outcomes (τb = -0.40 for HS vs. τb = 0.33 for GCS). ROC analyses affirmed HS's enhanced predictive accuracy over GCS for both mortality (AUC of 0.79 for HS vs. 0.62 for GCS) and overall outcomes (AUC of 0.77 for HS vs. 0.71 for GCS).

Conclusion: The findings validate the HS in a large German cohort and suggest that radiological assessments alone, as exemplified by HS, can surpass the traditional GCS in predicting TBI outcomes. However, the HS, despite its efficacy, lacks the integration of clinical evaluation, a vital component in TBI management. This underscores the necessity for a holistic approach that amalgamates both radiological and clinical insights for a more comprehensive and accurate prognostication in TBI care.

背景:创伤性脑损伤(TBI)的精确评估和预后对有效分流和知情治疗策略至关重要。虽然格拉斯哥昏迷量表(GCS)仍是评估创伤性脑损伤的基石,但它忽略了关键的主要影像学检查结果。赫尔辛基评分(HS)是一种结合放射学数据设计的新型工具,为预测创伤性脑损伤的预后提供了一种很有前景的方法。本研究旨在评估 HS 与 GCS 相比在大量 TBI 患者群中的预后效果:这项回顾性研究涵盖了 2008 年至 2019 年期间在我院接受治疗的 TBI 患者,特别是入院 GCS 为 14 或更低的患者。我们评估了初始 GCS 和主要 CT 扫描得出的 HS。主要结果指标包括格拉斯哥结果量表(GOS)和出院时以及出院后 6 个月和 12 个月的死亡率。通过接收者操作特征曲线(ROC)和 Kendall tau-b 相关系数分析了 GCS 和 HS 对每种结果的预测性能:研究纳入了 544 名患者,平均年龄为 62.2 ± 21.5 岁,初始 GCS 中位数为 14,HS 中位数为 3。出院时死亡率为 8.6%,GOS 中位数为 4:这些研究结果验证了德国大型队列中的 HS,并表明在预测创伤性脑损伤的预后方面,以 HS 为代表的单独放射学评估可以超越传统的 GCS。然而,HS 尽管有效,但缺乏临床评估的整合,而临床评估是 TBI 管理的重要组成部分。这突出表明,有必要采用一种综合方法,将放射学和临床见解结合起来,以便在创伤性脑损伤治疗中更全面、更准确地预测预后。
{"title":"Assessing outcomes in traumatic brain injury: Helsinki score versus Glasgow coma scale.","authors":"Fares Komboz, Hiba Douja Chehade, Bilal Al Saffar, Dorothee Mielke, Veit Rohde, Tammam Abboud","doi":"10.1007/s00068-024-02604-w","DOIUrl":"https://doi.org/10.1007/s00068-024-02604-w","url":null,"abstract":"<p><strong>Background: </strong>The precision of assessment and prognosis in traumatic brain injury (TBI) is paramount for effective triage and informed therapeutic strategies. While the Glasgow Coma Scale (GCS) remains the cornerstone for TBI evaluation, it overlooks critical primary imaging findings. The Helsinki Score (HS), a novel tool designed to incorporate radiological data, offers a promising approach to predicting TBI outcomes. This study aims to evaluate the prognostic efficacy of HS in comparison to GCS across a substantial TBI patient cohort.</p><p><strong>Methods: </strong>This retrospective study encompassed TBI patients treated at our institution between 2008 and 2019, specifically those with an admission GCS of 14 or lower. We assessed both the initial GCS and the HS derived from primary CT scans. Key outcome metrics included the Glasgow Outcome Scale (GOS) and mortality rates at hospital discharge and at 6 and 12-month intervals post-discharge. Predictive performances of GCS and HS were analyzed through Receiver Operating Characteristic (ROC) curves and Kendall tau-b correlation coefficients against each outcome.</p><p><strong>Results: </strong>The study included 544 patients, with an average age of 62.2 ± 21.5 years, median initial GCS of 14, and a median HS of 3. The mortality rate at discharge stood at 8.6%, with a median GOS of 4. Both GCS and HS demonstrated significant correlations with mortality and GOS outcomes (p < 0.05). Notably, HS showed a markedly superior correlation with mortality (τb = 0.36) compared to GCS (τb = -0.11) and with GOS outcomes (τb = -0.40 for HS vs. τb = 0.33 for GCS). ROC analyses affirmed HS's enhanced predictive accuracy over GCS for both mortality (AUC of 0.79 for HS vs. 0.62 for GCS) and overall outcomes (AUC of 0.77 for HS vs. 0.71 for GCS).</p><p><strong>Conclusion: </strong>The findings validate the HS in a large German cohort and suggest that radiological assessments alone, as exemplified by HS, can surpass the traditional GCS in predicting TBI outcomes. However, the HS, despite its efficacy, lacks the integration of clinical evaluation, a vital component in TBI management. This underscores the necessity for a holistic approach that amalgamates both radiological and clinical insights for a more comprehensive and accurate prognostication in TBI care.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trauma-related preventable death; data analysis and panel review at a level 1 trauma centre in Amsterdam, the Netherlands. 与创伤有关的可预防死亡;荷兰阿姆斯特丹一级创伤中心的数据分析和小组审查。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-07-25 DOI: 10.1007/s00068-024-02576-x
S Mikdad, N A G Hakkenbrak, W P Zuidema, U J L Reijnders, R J de Wit, E H Jansen, L A Schwarte, J W Schouten, F W Bloemers, G F Giannakopoulos, J A Halm

Purpose: Trauma-related death is used as a parameter to evaluate the quality of trauma care and identify cases in which mortality could have been prevented under optimal trauma care conditions. The aim of this study was to identify trauma-related preventable death (TRPD) within our institute by an external expert panel and to evaluate inter-panel reliability.

Methods: Trauma-related deaths between the 1st of January 2020 and the 1st of February 2022 at the Amsterdam University Medical Centre were identified. The severely injured patients (injury severity score ≥ 16) were enrolled for preventability analysis by an external multidisciplinary panel, consisting of a trauma surgeon, anaesthesiologist, emergency physician, neurosurgeon, and forensic physician. Case descriptions were provided, and panellists were asked to classify deaths as non-preventable, potentially preventable, and preventable. Agreements between the five observers were assessed by Fleiss kappa statistics.

Results: In total 95 trauma-related deaths were identified. Of which 36 fatalities were included for analysis, the mean age was 55.3 years (± 24.5), 69.4% were male and 88.9% suffered blunt trauma. The mean injury severity score was 35.3 (± 15.3). Interobserver agreement within the external panel was moderate for survivability (Fleiss kappa 0.474) but low for categorical preventable death classification (Fleiss kappa 0.298). Most of the disagreements were between non-preventable or potentially preventable with care that could have been improved.

Conclusion: Multidisciplinary panel review has a moderate inter-observer agreement regarding survivability and low agreement regarding categorical preventable death classification. A valid definition and classification of TRPD is required to improve inter-observer agreement and quality of trauma care.

目的:创伤相关死亡被用作评估创伤救治质量的参数,并确定在最佳创伤救治条件下本可避免死亡的病例。本研究的目的是由外部专家小组确定我院的创伤相关可预防死亡(TRPD),并评估小组间的可靠性:方法:对阿姆斯特丹大学医疗中心 2020 年 1 月 1 日至 2022 年 2 月 1 日期间与创伤相关的死亡病例进行鉴定。由创伤外科医生、麻醉师、急诊医生、神经外科医生和法医组成的外部多学科专家小组对重伤患者(受伤严重程度评分≥16分)进行可预防性分析。提供病例描述后,小组成员被要求将死亡分为不可预防、潜在可预防和可预防。通过弗莱斯卡帕(Fleiss kappa)统计来评估五位观察者之间的一致性:结果:共发现 95 例与创伤相关的死亡。平均年龄为 55.3 岁(± 24.5),69.4% 为男性,88.9% 遭受钝器创伤。平均受伤严重程度为 35.3(± 15.3)分。在存活率方面,外部专家小组的观察者之间的一致性为中等(Fleiss kappa 0.474),但在可预防死亡的分类方面,观察者之间的一致性较低(Fleiss kappa 0.298)。大多数分歧发生在非可预防或潜在可预防与本可改进的护理之间:结论:多学科小组评审在存活率方面的观察者间一致性为中等,而在可预防死亡分类方面的一致性较低。需要对 TRPD 进行有效定义和分类,以提高观察者之间的一致性和创伤护理质量。
{"title":"Trauma-related preventable death; data analysis and panel review at a level 1 trauma centre in Amsterdam, the Netherlands.","authors":"S Mikdad, N A G Hakkenbrak, W P Zuidema, U J L Reijnders, R J de Wit, E H Jansen, L A Schwarte, J W Schouten, F W Bloemers, G F Giannakopoulos, J A Halm","doi":"10.1007/s00068-024-02576-x","DOIUrl":"https://doi.org/10.1007/s00068-024-02576-x","url":null,"abstract":"<p><strong>Purpose: </strong>Trauma-related death is used as a parameter to evaluate the quality of trauma care and identify cases in which mortality could have been prevented under optimal trauma care conditions. The aim of this study was to identify trauma-related preventable death (TRPD) within our institute by an external expert panel and to evaluate inter-panel reliability.</p><p><strong>Methods: </strong>Trauma-related deaths between the 1st of January 2020 and the 1st of February 2022 at the Amsterdam University Medical Centre were identified. The severely injured patients (injury severity score ≥ 16) were enrolled for preventability analysis by an external multidisciplinary panel, consisting of a trauma surgeon, anaesthesiologist, emergency physician, neurosurgeon, and forensic physician. Case descriptions were provided, and panellists were asked to classify deaths as non-preventable, potentially preventable, and preventable. Agreements between the five observers were assessed by Fleiss kappa statistics.</p><p><strong>Results: </strong>In total 95 trauma-related deaths were identified. Of which 36 fatalities were included for analysis, the mean age was 55.3 years (± 24.5), 69.4% were male and 88.9% suffered blunt trauma. The mean injury severity score was 35.3 (± 15.3). Interobserver agreement within the external panel was moderate for survivability (Fleiss kappa 0.474) but low for categorical preventable death classification (Fleiss kappa 0.298). Most of the disagreements were between non-preventable or potentially preventable with care that could have been improved.</p><p><strong>Conclusion: </strong>Multidisciplinary panel review has a moderate inter-observer agreement regarding survivability and low agreement regarding categorical preventable death classification. A valid definition and classification of TRPD is required to improve inter-observer agreement and quality of trauma care.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Seasonal patterns of hip fracture incidence and mortality rates across age groups of older adults in Israel. 以色列各年龄组老年人髋部骨折发病率和死亡率的季节性模式。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-07-25 DOI: 10.1007/s00068-024-02569-w
Yaniv Yonai, Salim Masarwa, Merav Ben Natan, Yaron Berkovich

Purpose: This study investigates the seasonal patterns of hip fracture occurrence and mortality rates in the elderly population of Israel.

Methods: In this retrospective study, we examined a random sample of 400 patients who underwent a hip fracture repair surgery at a 495-bed hospital in northern-central Israel during the years 2021-2022.

Results: Our findings reveal a heightened incidence of hip fractures during the spring (30.8%) in contrast to relatively consistent rates during other seasons (22-24.2%). Patients experiencing hip fractures in the spring were notably younger and had shorter hospital stays compared to those in other seasons. Furthermore, we identified seasonal variations in hip fracture incidence concerning gender, culture, and nationality. Over the 2-year follow-up period, 20% of patients had succumbed to mortality. The highest survival rate was associated with hip fractures sustained in the spring, while the lowest rates were observed in the autumn and winter.

Conclusion: While our study highlights significant seasonal variations in hip fracture occurrence and mortality rates among the elderly population in Israel, caution is warranted in interpreting the implications for post-fracture care and resource allocation. The observed heightened incidence of hip fractures during the spring, particularly among younger patients with shorter hospital stays, suggests the need for further investigation into potential risk factors and preventive measures specific to this season. Additionally, our identification of seasonal variations in hip fracture incidence across demographic factors underscores the importance of tailored interventions to address the diverse needs of different populations.

目的:本研究调查了以色列老年人群中髋部骨折发生率和死亡率的季节性规律:在这项回顾性研究中,我们对 2021-2022 年期间在以色列中北部一家拥有 495 张病床的医院接受髋部骨折修复手术的 400 名患者进行了随机抽样:结果:我们的研究结果显示,春季髋部骨折的发病率较高(30.8%),而其他季节的发病率相对稳定(22-24.2%)。与其他季节相比,春季髋部骨折患者明显更年轻,住院时间更短。此外,我们还发现髋部骨折发病率在性别、文化和国籍方面存在季节性差异。在两年的随访期间,20%的患者死亡。春季髋部骨折患者的存活率最高,而秋季和冬季的存活率最低:虽然我们的研究强调了以色列老年人群中髋部骨折发生率和死亡率的显著季节性变化,但在解释其对骨折后护理和资源分配的影响时仍需谨慎。观察到春季髋部骨折的发生率较高,尤其是住院时间较短的年轻患者,这表明有必要进一步调查潜在的风险因素和针对这一季节的预防措施。此外,我们还发现髋部骨折发病率在不同人口因素中存在季节性差异,这突出了针对不同人群的不同需求采取有针对性的干预措施的重要性。
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引用次数: 0
Thoracolumbar spinal cord injury: management, techniques, timing. 胸腰椎脊髓损伤:管理、技术、时机。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-07-17 DOI: 10.1007/s00068-024-02595-8
Marko Jug, Radko Komadina, Klaus Wendt, Hans Christoph Pape, Frank Bloemers, Christoph Nau

Acute traumatic spinal cord injury (tSCI) is a complex and heterogeneous injury, where the level of injury, injury severity, duration and degree of spinal cord compression, and blood pressure management seem to influence neurologic outcome. Although data in the literature seem to be inconsistent regarding the effectiveness of surgical decompression and spinal fixation in patients with thoracic and thoracolumbar tSCI, some single-center studies suggest that early surgical decompression may lead to a superior neurologic outcome, especially in patients with incomplete tSCI, suggesting surgical decompression to be performed as soon as possible. However, high energy injuries, especially to the upper thoracic levels, may be too severe to be influenced by surgical decompression, which may represent a critical second hit for the polytraumatized patient. Therefore, the surgeon first needs to critically evaluate the potential for neurologic recovery in each patient before determining the ideal timing of surgery. Circulatory stabilization must be achieved before surgical intervention, and minimally invasive procedures should be preferred. Invasive blood pressure monitoring should be started on admission, and maintenance of a MAP between 85 and 90 mmHg is recommended for a duration of 5-7 days, with special attention to the prevention of hypoxia, fever, acidosis and deep venous thrombosis. The role of a 24-hour infusion of high-dose MPSS is still controversial, but it may be offered at the discretion of the treating surgeon to adult patients within 8 h of acute tSCI as a treatment option, especially in the case of very early decompression or incomplete tSCI.

急性创伤性脊髓损伤(tSCI)是一种复杂的异质性损伤,损伤程度、损伤严重性、脊髓受压时间和程度以及血压管理似乎都会影响神经功能的预后。虽然文献中关于胸椎和胸腰椎 tSCI 患者手术减压和脊柱固定效果的数据似乎并不一致,但一些单中心研究表明,早期手术减压可能会带来更好的神经功能预后,尤其是对于不完全 tSCI 患者,因此建议尽快进行手术减压。然而,高能量损伤,尤其是胸腔上层的高能量损伤可能过于严重,手术减压可能无法对其产生影响,而手术减压可能是多发性创伤患者关键的第二次打击。因此,外科医生首先需要严格评估每位患者神经功能恢复的可能性,然后再确定理想的手术时机。手术干预前必须实现循环稳定,并应首选微创手术。入院时就应开始有创血压监测,建议在 5-7 天内将血压维持在 85 至 90 mmHg 之间,并特别注意预防缺氧、发热、酸中毒和深静脉血栓形成。24 小时输注大剂量 MPSS 的作用仍存在争议,但作为一种治疗选择,尤其是在极早期减压或不完全 tSCI 的情况下,治疗外科医生可酌情在急性 tSCI 8 小时内为成人患者提供这种治疗。
{"title":"Thoracolumbar spinal cord injury: management, techniques, timing.","authors":"Marko Jug, Radko Komadina, Klaus Wendt, Hans Christoph Pape, Frank Bloemers, Christoph Nau","doi":"10.1007/s00068-024-02595-8","DOIUrl":"https://doi.org/10.1007/s00068-024-02595-8","url":null,"abstract":"<p><p>Acute traumatic spinal cord injury (tSCI) is a complex and heterogeneous injury, where the level of injury, injury severity, duration and degree of spinal cord compression, and blood pressure management seem to influence neurologic outcome. Although data in the literature seem to be inconsistent regarding the effectiveness of surgical decompression and spinal fixation in patients with thoracic and thoracolumbar tSCI, some single-center studies suggest that early surgical decompression may lead to a superior neurologic outcome, especially in patients with incomplete tSCI, suggesting surgical decompression to be performed as soon as possible. However, high energy injuries, especially to the upper thoracic levels, may be too severe to be influenced by surgical decompression, which may represent a critical second hit for the polytraumatized patient. Therefore, the surgeon first needs to critically evaluate the potential for neurologic recovery in each patient before determining the ideal timing of surgery. Circulatory stabilization must be achieved before surgical intervention, and minimally invasive procedures should be preferred. Invasive blood pressure monitoring should be started on admission, and maintenance of a MAP between 85 and 90 mmHg is recommended for a duration of 5-7 days, with special attention to the prevention of hypoxia, fever, acidosis and deep venous thrombosis. The role of a 24-hour infusion of high-dose MPSS is still controversial, but it may be offered at the discretion of the treating surgeon to adult patients within 8 h of acute tSCI as a treatment option, especially in the case of very early decompression or incomplete tSCI.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141633095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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European Journal of Trauma and Emergency Surgery
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