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Outcomes after open and endovascular treatment for mesenteric artery embolism patients: a retrospective inverse probability of treatment-weighted analysis. 肠系膜动脉栓塞患者接受开腹和血管内治疗后的疗效:一项回顾性逆治疗概率加权分析。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-27 DOI: 10.1007/s00068-024-02647-z
Yi-Hui Qiu, Yin-He Zhang, Zi-Chang Wu, Zhe Yang, Guan-Xia Zhu, Shou-Liang Miao, Bi-Cheng Chen, Fan-Feng Chen

Purpose: This study aims to evaluate outcomes in patients with mesenteric artery embolism (MAE) who received primary endovascular therapy (EVT) or laparotomy, and investigate risk factors for 30-day mortality.

Methods: A retrospective analysis of 94 MAE patients who underwent two different treatment strategies was undertaken. An inverse probability of treatment weighting (IPTW) method was used to balance the confounding effects of baseline clinical data. Logistic regression analysis was performed to compare the outcomes according to type of treatment regimens before and after IPTW. Univariate and multivariable analysis were conducted to determine the risk factors for 30-day mortality.

Results: Twenty-eight MAE patients received primary EVT, and 66 Open Surgery (OS). Logistic regression analysis showed that there was no significant difference between the EVT and OS group in 30-day mortality rate before (odds ratio [OR] 0.477, 95% confidence interval [CI] 0.170 to 1.340, P = 0.160), and after IPTW (OR 0.647, 95% CI 0.210 to 1.993, P = 0.449). After IPTW, it revealed that the rates of second-look surgery (OR 36.727, 95% CI 5.407 to 249.458, P < 0.001) and hospital stay [> 30 days] (OR 0.006, 95% CI 0.000 to 0.363, P = 0.014) were different in the two groups. D-dimer (> 4 mg/L) and procalcitonin (> 0.5 ng/mL) were the independent risk factors for 30-day mortality in MAE patients postoperatively (P < 0.05).

Conclusion: In this retrospective study, MAE patients who performed primary EVT had no obvious difference in 30-day mortality rate compared to those who received OS; but it was conducive to reducing prolonged hospital stays. An increase in procalcitonin level and higher D-dimer were associated with short-term poor prognosis in patients with MAE.

目的:本研究旨在评估接受初级血管内治疗(EVT)或开腹手术的肠系膜动脉栓塞(MAE)患者的预后,并调查30天死亡率的风险因素:对接受两种不同治疗策略的94例肠系膜动脉栓塞患者进行了回顾性分析。采用逆治疗概率加权(IPTW)法平衡基线临床数据的混杂效应。根据IPTW前后的治疗方案类型进行了逻辑回归分析,以比较结果。进行了单变量和多变量分析,以确定30天死亡率的风险因素:28名MAE患者接受了初级EVT,66名接受了开放手术(OS)。逻辑回归分析显示,EVT组和OS组的30天死亡率在IPTW前(比值比[OR]0.477,95%置信区间[CI]0.170至1.340,P=0.160)和IPTW后(比值比[OR]0.647,95%置信区间[CI]0.210至1.993,P=0.449)无显著差异。结果显示,IPTW 后,两组患者的二次手术率(OR 36.727,95% CI 5.407 至 249.458,P 30 天](OR 0.006,95% CI 0.000 至 0.363,P = 0.014)不同。D-二聚体(> 4 mg/L)和降钙素原(> 0.5 ng/mL)是MAE患者术后30天死亡的独立风险因素(P 结论:MAE患者术后30天死亡的独立风险因素为D-二聚体(> 4 mg/L)和降钙素原(> 0.5 ng/mL):在这项回顾性研究中,与接受OS治疗的MAE患者相比,接受初级EVT治疗的MAE患者30天死亡率没有明显差异,但有利于缩短住院时间。降钙素原水平升高和 D-二聚体升高与 MAE 患者的短期不良预后有关。
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引用次数: 0
Thoracolumbar injuries: operative treatment: indications, techniques, timing and implant removal. Current practice. 胸腰椎损伤:手术治疗:适应症、技术、时机和植入物取出。当前实践。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-27 DOI: 10.1007/s00068-024-02602-y
Frank Bloemers, Marko Jug, Christoph Nau, Radko Komadina, Hans Christoph Pape, Klaus Wendt

The operative treatment of thoracolumbar fractures is a rapidly evolving improvement in the care of patients with this injury after trauma. This article describes the different techniques and principles. Considerations and methods of treatment are scientifically addressed and illustrated according to the classification and severity of the fracture pattern. The use of computer navigation and optimisation of minimally invasive techniques is inevitable. The timing of surgery as well the removal of the material after fracture healing are also discussed. The operative treatment of spinal fractures is emerging and there is still much more knowledge to gain.

胸腰椎骨折的手术治疗是创伤后胸腰椎骨折患者护理中一项迅速发展的改进措施。本文介绍了不同的技术和原则。根据骨折形态的分类和严重程度,科学地阐述了治疗的注意事项和方法。计算机导航的使用和微创技术的优化是不可避免的。此外,还讨论了手术时机以及骨折愈合后材料的移除。脊柱骨折的手术治疗正在兴起,我们仍有许多知识需要学习。
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引用次数: 0
Is overweight a predictor for a more severe course of disease in cases of necrotizing fasciitis? 超重是否预示着坏死性筋膜炎的病程会更加严重?
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-27 DOI: 10.1007/s00068-024-02638-0
Claudius Illg, Markus Denzinger, Katarzyna Rachunek, Farhad Farzaliyev, Johannes T Thiel, Adrien Daigeler, Sabrina Krauss

Purpose: Necrotizing fasciitis is a rare but severe soft tissue infection, and its diagnosis is difficult and often delayed. Immediate treatment comprising extensive debridement, highly dosed broad-spectrum antibiotic therapy and intensive care is necessary to prevent fatal outcomes. Considering the global rise in overweight patients and the known negative effects of obesity on the immune system, the aim of this study was to analyze whether overweight results in a more severe course of necrotizing fasciitis, worse outcomes and an increased mortality rate among overweight patients compared than in normal weight patients.

Methods: The present study involved a retrospective analysis of 29 patients who were treated for necrotizing fasciitis in our level one trauma center during the eight-year period between 2013 and 2020. Based on their BMIs, the patients were assigned to either the overweight group (BMI > 25) or the normal weight group.

Results: In the study population, being overweight appeared to be a predictor for a more severe course of necrotizing fasciitis. Overweight patients suffered from sepsis significantly more often than normal weight patients (13 vs. 5; p = 0.027). Furthermore, they were dependent on invasive ventilation (26.6 ± 33.8 vs. 5.9 ± 11.9 days; p = 0.046) as well as catecholamine support (18.4 ± 23.7 vs. 3.6 ± 5.7 days; p = 0.039) for significantly longer.

Conclusion: Necrotizing fasciitis remains a challenging and potentially fatal disease. Within the patient collective, the severity of the disease and treatment effort were increased among overweight patients.

目的:坏死性筋膜炎是一种罕见但严重的软组织感染,诊断困难且经常延误。必须立即进行治疗,包括大面积清创、高剂量广谱抗生素治疗和重症监护,以防止致命后果的发生。考虑到全球超重患者的增加以及肥胖对免疫系统的负面影响,本研究旨在分析超重是否会导致坏死性筋膜炎的病程比正常体重患者更严重、治疗效果更差以及死亡率更高:本研究对 2013 年至 2020 年八年间在我们一级创伤中心接受坏死性筋膜炎治疗的 29 名患者进行了回顾性分析。根据体重指数,患者被分配到超重组(体重指数大于 25)或正常体重组:在研究人群中,超重似乎是导致坏死性筋膜炎病程更严重的一个预测因素。超重患者罹患败血症的频率明显高于正常体重患者(13 对 5;P = 0.027)。此外,他们依赖侵入性通气(26.6 ± 33.8 天 vs. 5.9 ± 11.9 天;p = 0.046)和儿茶酚胺支持(18.4 ± 23.7 天 vs. 3.6 ± 5.7 天;p = 0.039)的时间明显更长:结论:坏死性筋膜炎仍然是一种具有挑战性和潜在致命性的疾病。结论:坏死性筋膜炎仍然是一种具有挑战性和潜在致命性的疾病。在患者群体中,超重患者的病情严重程度和治疗难度都有所增加。
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引用次数: 0
Automatic virtual reconstruction of acetabular fractures using a statistical shape model. 利用统计形状模型自动虚拟重建髋臼骨折。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-27 DOI: 10.1007/s00068-024-02615-7
W A van Veldhuizen, R van Noortwijk, Aml Meesters, K Ten Duis, Rcl Schuurmann, Jppm de Vries, J M Wolterink, Ffa IJpma

Purpose: Automatic virtual reconstruction of complex fractures would be helpful for pre-operative surgical planning. We developed a statistical shape model (SSM) which contains data of 200 intact 3D hemipelves. It allows for quantification of shape differences and is able to reconstruct abnormal shaped pelvises. We applied our SSM to reconstruct elementary and associate type acetabular fractures and assessed the reconstruction performance of the SSM, by comparing the reconstructed shape with the intact contralateral hemipelvis.

Methods: In this retrospective diagnostic imaging study, we used our SSM to virtually reconstruct fractured hemipelves of eighty-three patients with an acetabular fracture. A root mean square error (RMSE) was computed between the reconstructed shape and intact contralateral shape for the whole hemipelvis and for regions relevant for plate-fitting. These plate-fitting relevant regions were defined as: (1) Iliopectineal line length and radius; (2) ischial body line length and radius; (3) acetabular diameter, (4) quadrilateral slope and (5) weight-bearing acetabular dome.

Results: The median RMSE of the whole hemipelvis of the elementary type fractures was 2.2 (1.7-2.5) mm versus 3.2 (2.2-3.9) mm for the associate type fractures (p < 0.001). The median RMSE for the plate-fitting regions of elementary type fractures was 1.7 (1.4-2.1) mm versus 2.7 (2.0-4.1) mm for associate type fractures (p < 0.001).

Conclusion: Using a statistical shape model allows for accurate virtual reconstructions of elementary and associate type acetabular fractures within a clinically acceptable range, especially within regions important for plate-fitting. SSM-based reconstructions can serve as a valuable tool for pre-operative planning in clinical practice, when a template of the contralateral hemipelvis is unavailable.

目的:复杂骨折的自动虚拟重建将有助于术前手术规划。我们开发了一种统计形状模型(SSM),其中包含 200 个完整三维半球的数据。它可以量化形状差异,并能重建异常形状的骨盆。我们将统计形状模型用于重建基本型和伴有型髋臼骨折,并通过比较重建后的形状和完整的对侧半盆来评估统计形状模型的重建性能:在这项回顾性诊断成像研究中,我们使用 SSM 对 83 名髋臼骨折患者的骨折半髋进行了虚拟重建。我们计算了整个半髋和与平板拟合相关区域的重建形状与完整对侧形状之间的均方根误差(RMSE)。这些平板拟合相关区域被定义为(1)髂骨线长度和半径;(2)峡体线长度和半径;(3)髋臼直径;(4)四边形斜率;(5)负重髋臼穹顶:结果:基本型骨折整个半骨盆的中位均方根误差为 2.2(1.7-2.5)毫米,而副型骨折为 3.2(2.2-3.9)毫米(P 结 论:使用统计形状模型可以准确测量骨折的半骨盆形状:使用统计形状模型可在临床可接受的范围内对基本型和伴行型髋臼骨折进行精确的虚拟重建,尤其是在对钢板装配非常重要的区域。在没有对侧半骨盆模板的情况下,基于 SSM 的重建可作为临床实践中术前规划的重要工具。
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引用次数: 0
Do we have to redefine type B-fractures of the rib cartilage? 我们是否需要重新定义肋软骨 B 型骨折?
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-27 DOI: 10.1007/s00068-024-02631-7
Johannes Groh, Florian Kern, Mario Perl, Stefan Schulz-Drost

Objectives: Aim of this work was the evaluation and validation of the AO/OTA classification of the anterior chest wall, here especially for the rib cartilage.

Methods: Study design was a retrospective analysis of patients who were hospitalized with fractures of the thoracic wall in the years 2010-2016. This resulted in a collective of n = 124 patients. All fractures of the anterior chest wall were classified according to their location, dislocation and fracture type according to the AO classification. An analysis of possible subtypes was carried out.

Results: 29.0% (36) of the patients had fractures of the rib cartilage. 23 of the 36 (64%) patients had multiple fractures, the total number of single fractures amounted to 94. 53.2% (50) of these fractures were in the right hemithorax, 46.8% (44) in the left hemithorax. 95.7% (90) of the fractures were A-fractures, 4.3% (4) were C-fractures. There were no B fractures. The C fractures also consisted exclusively of A fractures (AA fractures). 59.6% (56) of the fractures showed a dislocation. 30.9% (29) were avulsion fractures of either the osteochondral (22.3% (21)) or the sternocostal junction (8.5% (8)).

Discussion and conclusion: The costal cartilage obviously does not show typical B fractures as we know them from shaft fractures of long bones. We have compiled a structured analysis in the attached manuscript and validated the classification proposal. In conclusion, we propose an adaptation of the classification proposal based on our data with redefining type B fractures as fractures of the osteochondral joints.

目的:这项工作的目的是评估和验证前胸壁的 AO/OTA 分类,尤其是肋软骨:这项工作的目的是评估和验证前胸壁的 AO/OTA 分类,尤其是肋软骨的 AO/OTA 分类:研究设计是对 2010-2016 年期间因胸壁骨折住院的患者进行回顾性分析。共有 124 名患者。所有前胸壁骨折均按照 AO 分类法,根据骨折位置、脱位和骨折类型进行分类。结果:29.0%(36 例)的患者肋软骨骨折。这些骨折中有 53.2%(50 例)发生在右半胸,46.8%(44 例)发生在左半胸。95.7%(90 例)的骨折为 A 型骨折,4.3%(4 例)为 C 型骨折。没有 B 型骨折。C型骨折中也只有A型骨折(AA型骨折)。59.6%(56 例)的骨折出现脱位。30.9%(29例)为骨软骨(22.3%(21例))或胸骨骨膜交界处(8.5%(8例))的撕脱性骨折:讨论与结论:肋软骨显然不属于我们所熟知的长骨轴突骨折中典型的B型骨折。我们在所附手稿中进行了结构分析,并验证了分类建议。总之,我们建议根据我们的数据对分类建议进行调整,将 B 型骨折重新定义为骨软骨关节骨折。
{"title":"Do we have to redefine type B-fractures of the rib cartilage?","authors":"Johannes Groh, Florian Kern, Mario Perl, Stefan Schulz-Drost","doi":"10.1007/s00068-024-02631-7","DOIUrl":"https://doi.org/10.1007/s00068-024-02631-7","url":null,"abstract":"<p><strong>Objectives: </strong>Aim of this work was the evaluation and validation of the AO/OTA classification of the anterior chest wall, here especially for the rib cartilage.</p><p><strong>Methods: </strong>Study design was a retrospective analysis of patients who were hospitalized with fractures of the thoracic wall in the years 2010-2016. This resulted in a collective of n = 124 patients. All fractures of the anterior chest wall were classified according to their location, dislocation and fracture type according to the AO classification. An analysis of possible subtypes was carried out.</p><p><strong>Results: </strong>29.0% (36) of the patients had fractures of the rib cartilage. 23 of the 36 (64%) patients had multiple fractures, the total number of single fractures amounted to 94. 53.2% (50) of these fractures were in the right hemithorax, 46.8% (44) in the left hemithorax. 95.7% (90) of the fractures were A-fractures, 4.3% (4) were C-fractures. There were no B fractures. The C fractures also consisted exclusively of A fractures (AA fractures). 59.6% (56) of the fractures showed a dislocation. 30.9% (29) were avulsion fractures of either the osteochondral (22.3% (21)) or the sternocostal junction (8.5% (8)).</p><p><strong>Discussion and conclusion: </strong>The costal cartilage obviously does not show typical B fractures as we know them from shaft fractures of long bones. We have compiled a structured analysis in the attached manuscript and validated the classification proposal. In conclusion, we propose an adaptation of the classification proposal based on our data with redefining type B fractures as fractures of the osteochondral joints.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
No-drain strategy for perforated peptic ulcer: no consensus yet. 消化性溃疡穿孔的免引流策略:尚未达成共识。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-27 DOI: 10.1007/s00068-024-02650-4
Masayuki Urabe, Yojiro Hashiguchi
{"title":"No-drain strategy for perforated peptic ulcer: no consensus yet.","authors":"Masayuki Urabe, Yojiro Hashiguchi","doi":"10.1007/s00068-024-02650-4","DOIUrl":"https://doi.org/10.1007/s00068-024-02650-4","url":null,"abstract":"","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterization and treatment protocol of injuries inflicted to humans by synurbic European wild boars (Sus scrofa). 欧洲野猪(Sus scrofa)对人类造成伤害的特征和治疗方案。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-27 DOI: 10.1007/s00068-024-02654-0
Oriol Pujol, Miguel Nuño, Joan Minguell, Jordi Selga, Jordi Tomás, Dolors Rodríguez, Xavier Martínez, Gregorio Mentaberre, Jorge Ramón López-Olvera

Purpose: Wild boar (Sus scrofa) has spread and colonized urban areas. The closer contact with humans can lead to wild boar-inflicted injuries. The objectives of this study are: 1) to systematically review the literature on wild boar-inflicted injuries; 2) to describe our wild boar-inflicted wound management protocol; and 3) to analyse the features, outcomes and complications of our case series.

Methods: First, a systematic search of the literature was performed using the PubMed (MEDLINE) electronic database. Then, our evidence-based wild boar-inflicted wound management protocol was described. Finally, a retrospective case series study including all the patients with wild boar-inflicted injuries attended in our Emergency Department (2020-2022) was analysed.

Results: Fourteen studies (twelve case reports and two case series) were selected for the literature review. Our case series included 34 patients: 50.0% of them presented superficial wounds and 38.2% penetrating wounds. Most of the wounds occurred in the lower limbs (71.9%). Following our protocol, 30.0% of the wounds were primarily closed, the 70.0% of the patients received antibiotics (92.3% in penetrating injuries) and the 26.7% received an antitetanic vaccine. Only one patient (2.9%) presented a complication.

Conclusions: This study reports the first specific wild boar inflicted-wound management protocol, which led to a low complication rate. Open wounds affecting the lower limbs were the most common lesions. Care should be taken with penetrating tusk injuries. Wide-spectrum antibiotic and antitetanic treatments are recommended. Decisions on wound management should be taken case-by-case, while antirabies vaccination depends on the local status of the disease.

目的:野猪(Sus scrofa)已在城市地区蔓延和定居。与人类的密切接触可能导致野猪造成的伤害。本研究的目的是1)系统回顾有关野猪致伤的文献;2)描述我们的野猪致伤处理方案;3)分析我们的系列病例的特征、结果和并发症:首先,使用 PubMed(MEDLINE)电子数据库对文献进行了系统检索。然后,介绍了我们以证据为基础的野猪致伤伤口处理方案。最后,我们分析了一项回顾性病例系列研究,其中包括我们急诊科就诊的所有野猪致伤患者(2020-2022 年):文献综述选取了 14 项研究(12 项病例报告和 2 项病例系列)。我们的病例系列包括 34 名患者:其中50.0%为浅表伤口,38.2%为穿透伤。大多数伤口发生在下肢(71.9%)。按照我们的方案,30.0%的伤口主要是闭合伤口,70.0%的患者接受了抗生素治疗(92.3%为穿透伤),26.7%的患者接受了抗乙烷疫苗治疗。只有一名患者(2.9%)出现了并发症:本研究报告了首个特定的野猪致伤处理方案,其并发症发生率较低。影响下肢的开放性伤口是最常见的病变。对穿透性獠牙伤应谨慎处理。建议使用广谱抗生素和抗毒素治疗。伤口处理应视具体情况而定,而抗伊拉巴斯疫苗接种则取决于当地的疾病状况。
{"title":"Characterization and treatment protocol of injuries inflicted to humans by synurbic European wild boars (Sus scrofa).","authors":"Oriol Pujol, Miguel Nuño, Joan Minguell, Jordi Selga, Jordi Tomás, Dolors Rodríguez, Xavier Martínez, Gregorio Mentaberre, Jorge Ramón López-Olvera","doi":"10.1007/s00068-024-02654-0","DOIUrl":"https://doi.org/10.1007/s00068-024-02654-0","url":null,"abstract":"<p><strong>Purpose: </strong>Wild boar (Sus scrofa) has spread and colonized urban areas. The closer contact with humans can lead to wild boar-inflicted injuries. The objectives of this study are: 1) to systematically review the literature on wild boar-inflicted injuries; 2) to describe our wild boar-inflicted wound management protocol; and 3) to analyse the features, outcomes and complications of our case series.</p><p><strong>Methods: </strong>First, a systematic search of the literature was performed using the PubMed (MEDLINE) electronic database. Then, our evidence-based wild boar-inflicted wound management protocol was described. Finally, a retrospective case series study including all the patients with wild boar-inflicted injuries attended in our Emergency Department (2020-2022) was analysed.</p><p><strong>Results: </strong>Fourteen studies (twelve case reports and two case series) were selected for the literature review. Our case series included 34 patients: 50.0% of them presented superficial wounds and 38.2% penetrating wounds. Most of the wounds occurred in the lower limbs (71.9%). Following our protocol, 30.0% of the wounds were primarily closed, the 70.0% of the patients received antibiotics (92.3% in penetrating injuries) and the 26.7% received an antitetanic vaccine. Only one patient (2.9%) presented a complication.</p><p><strong>Conclusions: </strong>This study reports the first specific wild boar inflicted-wound management protocol, which led to a low complication rate. Open wounds affecting the lower limbs were the most common lesions. Care should be taken with penetrating tusk injuries. Wide-spectrum antibiotic and antitetanic treatments are recommended. Decisions on wound management should be taken case-by-case, while antirabies vaccination depends on the local status of the disease.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The economic impact of open lower limb fractures in the Netherlands: a cost-of-illness study. 荷兰开放性下肢骨折的经济影响:疾病成本研究。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-26 DOI: 10.1007/s00068-024-02637-1
M P Noorlander-Borgdorff, W Kievit, G F Giannakópoulos, M Botman, T N Tromp, K Oflazoglu, H A Rakhorst, T de Jong

Purpose: To estimate the one-year sum of direct costs related to open lower limb fracture treatment in an academic setting in the Netherlands. The secondary objective was to estimate the impact of deep infection and nonunion on one-year total direct costs.

Methods: A multi-center, retrospective cost analysis of open lower limb fractures treated in an academic setting in the Netherlands, between 1 January 2017 and 31 December 2018, was conducted. The costing methodology was based on patient level aggregation using a bottom-up approach. A multiple linear regression model was used to predict the total costs based on Fracture-related-infections, multitrauma, intensive care unit (ICU) admission, Gustilo-Anderson grade and nonunion.

Results: Overall, 70 fractures were included for analysis, the majority Gustilo-Anderson grade III fractures (57%). Median (IQR) one-year hospital costs were €31,258 (20,812-58,217). Costs were primarily attributed to the length of hospital stay (58%) and surgical procedures (30%). The median length of stay was 16 days, with an increase to 50 days in Fracture-related infections. Subsequent costs (46,075 [25,891-74,938] vs. 15,244 [8970-30,173]; p = 0.002), and total hospital costs (90,862 [52,868-125,004] vs. 29,297 [21,784-40,677]; p < 0.001) were significantly higher for infected cases. It was found that Fracture-related infection, multitrauma, and Gustilo-Anderson grade IIIA-C fractures were significant predictors of increased costs.

Conclusion: In treatment of open lower limb fractures, deep infection, higher Gustilo-Anderson classification, and multitrauma significantly increase direct hospital costs. Considering the impact of infection on morbidity and total healthcare costs, future research should focus on preventing Fracture-related infections.

目的:估算荷兰学术机构开放性下肢骨折治疗一年的直接费用总和。次要目的是估算深度感染和不愈合对一年直接费用总额的影响:对 2017 年 1 月 1 日至 2018 年 12 月 31 日期间在荷兰学术机构治疗的开放性下肢骨折进行了多中心、回顾性成本分析。成本计算方法采用自下而上的方法,基于患者层面的汇总。采用多元线性回归模型,根据骨折相关感染、多发创伤、入住重症监护室(ICU)、古斯蒂洛-安德森分级和未愈合等因素预测总成本:共有 70 例骨折纳入分析,其中大多数为古斯蒂洛-安德森 III 级骨折(57%)。一年住院费用的中位数(IQR)为31,258欧元(20,812-58,217)。费用主要来自住院时间(58%)和外科手术(30%)。住院时间的中位数为 16 天,骨折相关感染的住院时间增加到 50 天。后续费用(46,075 [25,891-74,938] vs. 15,244 [8970-30,173]; p = 0.002)和住院总费用(90,862 [52,868-125,004] vs. 29,297 [21,784-40,677]; p 结论:在治疗开放性下肢骨折时,深度感染、较高的 Gustilo-Anderson 分级和多发创伤会显著增加直接住院费用。考虑到感染对发病率和医疗总成本的影响,未来的研究应侧重于预防骨折相关感染。
{"title":"The economic impact of open lower limb fractures in the Netherlands: a cost-of-illness study.","authors":"M P Noorlander-Borgdorff, W Kievit, G F Giannakópoulos, M Botman, T N Tromp, K Oflazoglu, H A Rakhorst, T de Jong","doi":"10.1007/s00068-024-02637-1","DOIUrl":"https://doi.org/10.1007/s00068-024-02637-1","url":null,"abstract":"<p><strong>Purpose: </strong>To estimate the one-year sum of direct costs related to open lower limb fracture treatment in an academic setting in the Netherlands. The secondary objective was to estimate the impact of deep infection and nonunion on one-year total direct costs.</p><p><strong>Methods: </strong>A multi-center, retrospective cost analysis of open lower limb fractures treated in an academic setting in the Netherlands, between 1 January 2017 and 31 December 2018, was conducted. The costing methodology was based on patient level aggregation using a bottom-up approach. A multiple linear regression model was used to predict the total costs based on Fracture-related-infections, multitrauma, intensive care unit (ICU) admission, Gustilo-Anderson grade and nonunion.</p><p><strong>Results: </strong>Overall, 70 fractures were included for analysis, the majority Gustilo-Anderson grade III fractures (57%). Median (IQR) one-year hospital costs were €31,258 (20,812-58,217). Costs were primarily attributed to the length of hospital stay (58%) and surgical procedures (30%). The median length of stay was 16 days, with an increase to 50 days in Fracture-related infections. Subsequent costs (46,075 [25,891-74,938] vs. 15,244 [8970-30,173]; p = 0.002), and total hospital costs (90,862 [52,868-125,004] vs. 29,297 [21,784-40,677]; p < 0.001) were significantly higher for infected cases. It was found that Fracture-related infection, multitrauma, and Gustilo-Anderson grade IIIA-C fractures were significant predictors of increased costs.</p><p><strong>Conclusion: </strong>In treatment of open lower limb fractures, deep infection, higher Gustilo-Anderson classification, and multitrauma significantly increase direct hospital costs. Considering the impact of infection on morbidity and total healthcare costs, future research should focus on preventing Fracture-related infections.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142072349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Key performance indicators and benchmarks in MCI prehospital response using technological tools: a qualitative study assessing the perception of practitioners and tool developers. 使用技术工具进行 MCI 院前响应的关键绩效指标和基准:一项评估从业人员和工具开发人员看法的定性研究。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-22 DOI: 10.1007/s00068-024-02627-3
Hamdi Lamine, Nikolaos Markou-Pappas, Luca Ragazzoni, Marta Caviglia

Purpose: The aim of this study is to investigate the opinions and perspectives of The Novel Integrated Toolkit for Enhanced Prehospital Life Support and Triage in Challenging and Large Emergencies (NIGHTINGALE) end-users and tool developers regarding Key Performance Indicators (KPIs) and benchmarks that assess the prehospital response to Mass Casualty Incidents (MCIs) enhanced by the NIT-MR.

Methods: A qualitative study employing focus group discussions was conducted to collect opinions and perspectives of end-users and tool developers regarding KPIs and benchmarks in MCI response using the NIT-MR. The criteria considered for the selection and distribution of participants within the groups was the nature of their involvement within the NIGHTINGALE project and their familiarity with the tools to be discussed.

Results: Thirty-one participants from different countries were included. Four themes emerged during data analysis which are: definition/explanation is the personal understanding of participants of the term KPI, process of KPI development and relationship with User Requirements is the decision process for assigning KPIs to user requirements, benchmarking is the mental process of associating a benchmark to a KPI or for developing a benchmark, and technical/medical gap is the gap of understanding between each sides' fields.

Conclusion: This study emphasized the need for a structured approach to using KPIs and bridging the gap between technological and medical worlds, taking the NIGHTINGALE project, funded by the European Union, which aims to develop a technological toolkit for first responders in mass casualty incidents as an example. These insights are crucial for enhancing disaster response.

目的:本研究旨在调查 "在具有挑战性的大型突发事件中加强院前生命支持和分诊的新型综合工具包"(NIGHTINGALE)的最终用户和工具开发人员对关键绩效指标(KPI)和基准的看法和观点,这些指标和基准用于评估通过 NIT-MR 加强的对大规模伤亡事件(MCI)的院前响应:方法:采用焦点小组讨论的方式开展了一项定性研究,以收集最终用户和工具开发人员对使用 NIT-MR 的 MCI 响应关键绩效指标和基准的意见和看法。小组参与者的选择和分配标准是他们参与 NIGHTINGALE 项目的性质以及他们对将要讨论的工具的熟悉程度:来自不同国家的 31 名参与者参加了小组讨论。在数据分析过程中出现了四个主题,分别是:定义/解释是指参与者对 KPI 一词的个人理解;KPI 开发过程及与用户需求的关系是指将 KPI 分配给用户需求的决策过程;基准是指将基准与 KPI 相关联或开发基准的心理过程;技术/医学差距是指双方领域之间的理解差距:本研究强调了使用关键绩效指标的结构化方法以及弥合技术与医疗领域差距的必要性,并以欧盟资助的 NIGHTINGALE 项目为例,该项目旨在为大规模伤亡事件中的急救人员开发一套技术工具包。这些见解对于加强灾难应对工作至关重要。
{"title":"Key performance indicators and benchmarks in MCI prehospital response using technological tools: a qualitative study assessing the perception of practitioners and tool developers.","authors":"Hamdi Lamine, Nikolaos Markou-Pappas, Luca Ragazzoni, Marta Caviglia","doi":"10.1007/s00068-024-02627-3","DOIUrl":"https://doi.org/10.1007/s00068-024-02627-3","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of this study is to investigate the opinions and perspectives of The Novel Integrated Toolkit for Enhanced Prehospital Life Support and Triage in Challenging and Large Emergencies (NIGHTINGALE) end-users and tool developers regarding Key Performance Indicators (KPIs) and benchmarks that assess the prehospital response to Mass Casualty Incidents (MCIs) enhanced by the NIT-MR.</p><p><strong>Methods: </strong>A qualitative study employing focus group discussions was conducted to collect opinions and perspectives of end-users and tool developers regarding KPIs and benchmarks in MCI response using the NIT-MR. The criteria considered for the selection and distribution of participants within the groups was the nature of their involvement within the NIGHTINGALE project and their familiarity with the tools to be discussed.</p><p><strong>Results: </strong>Thirty-one participants from different countries were included. Four themes emerged during data analysis which are: definition/explanation is the personal understanding of participants of the term KPI, process of KPI development and relationship with User Requirements is the decision process for assigning KPIs to user requirements, benchmarking is the mental process of associating a benchmark to a KPI or for developing a benchmark, and technical/medical gap is the gap of understanding between each sides' fields.</p><p><strong>Conclusion: </strong>This study emphasized the need for a structured approach to using KPIs and bridging the gap between technological and medical worlds, taking the NIGHTINGALE project, funded by the European Union, which aims to develop a technological toolkit for first responders in mass casualty incidents as an example. These insights are crucial for enhancing disaster response.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Publisher Correction: European society for trauma and emergency surgery member-identified research priorities in emergency surgery: a roadmap for future clinical research opportunities. 出版商更正:欧洲创伤和急诊外科协会会员确定的急诊外科研究重点:未来临床研究机会路线图。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2024-08-22 DOI: 10.1007/s00068-024-02600-0
Gary Alan Bass, Lewis Jay Kaplan, Christine Gaarder, Raul Coimbra, Nathan John Klingensmith, Hayato Kurihara, Mauro Zago, Stefano Piero Bernardo Cioffi, Shahin Mohseni, Michael Sugrue, Matti Tolonen, Cristina Rey Valcarcel, Jonathan Tilsed, Frank Hildebrand, Ingo Marzi
{"title":"Publisher Correction: European society for trauma and emergency surgery member-identified research priorities in emergency surgery: a roadmap for future clinical research opportunities.","authors":"Gary Alan Bass, Lewis Jay Kaplan, Christine Gaarder, Raul Coimbra, Nathan John Klingensmith, Hayato Kurihara, Mauro Zago, Stefano Piero Bernardo Cioffi, Shahin Mohseni, Michael Sugrue, Matti Tolonen, Cristina Rey Valcarcel, Jonathan Tilsed, Frank Hildebrand, Ingo Marzi","doi":"10.1007/s00068-024-02600-0","DOIUrl":"https://doi.org/10.1007/s00068-024-02600-0","url":null,"abstract":"","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":null,"pages":null},"PeriodicalIF":1.9,"publicationDate":"2024-08-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142016816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
European Journal of Trauma and Emergency Surgery
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