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Surgical stabilization of posterior rib fractures involving the costotransverse joint.
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2025-03-05 DOI: 10.1007/s00068-025-02797-8
Astrid Carolina Álvarez-Ortega, Jose Alejandro Posso-Nuñez, Nicolás Felipe Torres-España, Carlos Alejandro García-González, Álvaro I Sánchez-Ortiz, Mauricio Velásquez-Galvis

Purpose: Surgical stabilization of posterior rib fractures involving the costotransverse joint is debated, with most patients managed non-operatively. However, surgery may be indicated for respiratory failure due to altered mechanics or severe pain leading to functional limitations. Long-term outcomes related to quality of life and pulmonary function in these patients are underreported. This study aimed to describe our unique experience with the surgical stabilization of posterior rib fractures involving the costotransverse joint and to report the associated outpatient clinical outcomes.

Methods: An observational descriptive study was conducted at a tertiary care institution in Colombia during 2020-2024. Patients with posterior rib fractures involving the costotransverse joint who underwent surgery were included. Data collected included demographics, trauma severity, and complication rates. Primary outcomeswere mortality, postoperative complications, and implant failure.

Results: Eleven patients were included, with a median age of 42 years (interquartile range [IQR] 35-53). The median Injury Severity Score was 26 [IQR 21-35]. The median hospital length of stay was 13 days [IQR 10-17], Intensive care unit stay was 7 days [IQR 4-10], and invasive mechanical ventilation duration was 4 days [IQR 3-4]. One patient (9.1%) experienced a postoperative surgical site infection. Pulmonary function tests revealed a median forced vital capacity at 66% of the predicted value [IQR: 63-73%] and a median forced expiratory volume in the first second at 65% of the predicted value [IQR: 64-70%]. Quality of life assessments indicated acceptable outcomes, with a median score of 60 points [IQR 50-75].

Conclusion: Surgical stabilization of posterior rib fractures involving the costotransverse joint is feasible and yields favorable outcomes, overcoming many technical hurdles. Larger studies with standardized follow-up are needed to validate these findings and establish definitive management guidelines.

{"title":"Surgical stabilization of posterior rib fractures involving the costotransverse joint.","authors":"Astrid Carolina Álvarez-Ortega, Jose Alejandro Posso-Nuñez, Nicolás Felipe Torres-España, Carlos Alejandro García-González, Álvaro I Sánchez-Ortiz, Mauricio Velásquez-Galvis","doi":"10.1007/s00068-025-02797-8","DOIUrl":"https://doi.org/10.1007/s00068-025-02797-8","url":null,"abstract":"<p><strong>Purpose: </strong>Surgical stabilization of posterior rib fractures involving the costotransverse joint is debated, with most patients managed non-operatively. However, surgery may be indicated for respiratory failure due to altered mechanics or severe pain leading to functional limitations. Long-term outcomes related to quality of life and pulmonary function in these patients are underreported. This study aimed to describe our unique experience with the surgical stabilization of posterior rib fractures involving the costotransverse joint and to report the associated outpatient clinical outcomes.</p><p><strong>Methods: </strong>An observational descriptive study was conducted at a tertiary care institution in Colombia during 2020-2024. Patients with posterior rib fractures involving the costotransverse joint who underwent surgery were included. Data collected included demographics, trauma severity, and complication rates. Primary outcomeswere mortality, postoperative complications, and implant failure.</p><p><strong>Results: </strong>Eleven patients were included, with a median age of 42 years (interquartile range [IQR] 35-53). The median Injury Severity Score was 26 [IQR 21-35]. The median hospital length of stay was 13 days [IQR 10-17], Intensive care unit stay was 7 days [IQR 4-10], and invasive mechanical ventilation duration was 4 days [IQR 3-4]. One patient (9.1%) experienced a postoperative surgical site infection. Pulmonary function tests revealed a median forced vital capacity at 66% of the predicted value [IQR: 63-73%] and a median forced expiratory volume in the first second at 65% of the predicted value [IQR: 64-70%]. Quality of life assessments indicated acceptable outcomes, with a median score of 60 points [IQR 50-75].</p><p><strong>Conclusion: </strong>Surgical stabilization of posterior rib fractures involving the costotransverse joint is feasible and yields favorable outcomes, overcoming many technical hurdles. Larger studies with standardized follow-up are needed to validate these findings and establish definitive management guidelines.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"127"},"PeriodicalIF":1.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Which side should be taken care of when positioning a lag screw in intertrochanteric femoral fracture: right or left?
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2025-03-04 DOI: 10.1007/s00068-025-02790-1
Min Uk Do, Kyeong Baek Kim, Sang-Min Lee, Hyun Tae Koo, Won Chul Shin

Purpose: We aimed to demonstrate which side should be taken care of when fixating an intramedullary nail with a lag screw for an intertrochanteric fracture under the influence of clockwise torque.

Methods: From 2021 to 2023, 63 patients who underwent surgery for intertrochanteric fractures were divided into two groups: Group A (45 patients with left-side fractures) and Group B (18 patients with right-side fractures). We evaluated intraoperative images before fixation and postoperative radiographs to assess anteromedial cortical support. Clinically, the time to union and union rate were evaluated, and the complications, reoperation, and Koval score at one year were reviewed.

Results: Pre-fixation reduction quality showed no significant difference between groups. However, in terms of postoperative reduction quality on the lateral view, Group A had the highest incidence of neutral anterior cortical support (ACS) (62%), whereas Group B had the highest incidence of negative ACS (78%) (p < 0.001). Bone union occurred in 98% of Group A cases and 78% of Group B cases (p = 0.021). The mean time to union was shorter in Group A (5.2 months) compared to Group B (5.8 months) (p = 0.004). The mean Koval score was also better in Group A (2.4 vs. 2.0, p = 0.031).

Conclusion: When fixating intertrochanteric fractures with an intramedullary nail using a lag screw, right-sided fractures tended to exhibit negative ACS on lateral radiographs by clockwise torque. Therefore, particular attention should be paid to maintaining proper reduction while fixating right-sided intertrochanteric fractures.

{"title":"Which side should be taken care of when positioning a lag screw in intertrochanteric femoral fracture: right or left?","authors":"Min Uk Do, Kyeong Baek Kim, Sang-Min Lee, Hyun Tae Koo, Won Chul Shin","doi":"10.1007/s00068-025-02790-1","DOIUrl":"https://doi.org/10.1007/s00068-025-02790-1","url":null,"abstract":"<p><strong>Purpose: </strong>We aimed to demonstrate which side should be taken care of when fixating an intramedullary nail with a lag screw for an intertrochanteric fracture under the influence of clockwise torque.</p><p><strong>Methods: </strong>From 2021 to 2023, 63 patients who underwent surgery for intertrochanteric fractures were divided into two groups: Group A (45 patients with left-side fractures) and Group B (18 patients with right-side fractures). We evaluated intraoperative images before fixation and postoperative radiographs to assess anteromedial cortical support. Clinically, the time to union and union rate were evaluated, and the complications, reoperation, and Koval score at one year were reviewed.</p><p><strong>Results: </strong>Pre-fixation reduction quality showed no significant difference between groups. However, in terms of postoperative reduction quality on the lateral view, Group A had the highest incidence of neutral anterior cortical support (ACS) (62%), whereas Group B had the highest incidence of negative ACS (78%) (p < 0.001). Bone union occurred in 98% of Group A cases and 78% of Group B cases (p = 0.021). The mean time to union was shorter in Group A (5.2 months) compared to Group B (5.8 months) (p = 0.004). The mean Koval score was also better in Group A (2.4 vs. 2.0, p = 0.031).</p><p><strong>Conclusion: </strong>When fixating intertrochanteric fractures with an intramedullary nail using a lag screw, right-sided fractures tended to exhibit negative ACS on lateral radiographs by clockwise torque. Therefore, particular attention should be paid to maintaining proper reduction while fixating right-sided intertrochanteric fractures.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"125"},"PeriodicalIF":1.9,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predictive ability of frailty scores in surgically managed patients with traumatic spinal injuries: a TQIP analysis.
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2025-03-04 DOI: 10.1007/s00068-025-02775-0
Maximilian Peter Forssten, Lovisa Ekestubbe, Yang Cao, Ahmad Mohammad Ismail, Ioannis Ioannidis, Babak Sarani, Shahin Mohseni

Purpose: Frailty has gained recognition as a crucial determinant of patient outcomes following traumatic spinal injury (TSI), particularly due to its increasing incidence in elderly populations. The aim of the current investigation was therefore to compare the ability of several frailty scores to predict adverse outcomes in surgically managed isolated TSI patients without spinal cord injury.

Methods: All adult patients (18 years or older) who suffered an isolated TSI due to blunt trauma, and required surgical management, were extracted from the 2013-2021 Trauma Quality Improvement Program database. The ability of the Orthopedic Frailty Score (OFS), the Hospital Frailty Risk Score (HFRS), the 11-factor (11-mFI) and 5-factor (5-mFI) modified frailty index, as well as the Johns Hopkins Frailty Indicator to predict adverse outcomes was compared based on the area under the receiver-operating characteristic curve (AUC). Subgroup analyses were also performed on patients who were ≥ 65 years old and those who were injured due to a ground-level fall (GLF).

Results: A total of 39,449 patients were selected from the TQIP database. The 5-mFI and 11-mFI outperformed all other frailty scores when predicting in-hospital mortality (5-mFI AUC: 0.73) (11-mFI AUC: 0.73), any complication (5-mFI AUC: 0.65) (11-mFI AUC: 0.65), and FTR (5-mFI AUC: 0.75) (11-mFI AUC: 0.75). Among the 14,257 geriatric patients, however, the OFS demonstrated the highest predictive ability for in-hospital mortality (AUC: 0.65). The OFS (AUC: 0.64) also performed on the same level as both the 5-mFI (AUC: 0.63) and the 11-mFI (AUC: 0.63) when predicting FTR in this population. Among the 9616 patients who were injured due to a GLF, the OFS performed on par with the 5-mFI and 11-mFI when predicting in-hospital mortality and FTR.

Conclusion: Simpler scores like the 5-factor modified Frailty Index and Orthopedic Frailty Score outperform or perform on par with more complicated frailty scores when predicting mortality, complications, and failure-to-rescue in surgically managed isolated traumatic spinal injury patients without spinal cord injury, particularly among geriatric patients and those injured in a GLF.

{"title":"Predictive ability of frailty scores in surgically managed patients with traumatic spinal injuries: a TQIP analysis.","authors":"Maximilian Peter Forssten, Lovisa Ekestubbe, Yang Cao, Ahmad Mohammad Ismail, Ioannis Ioannidis, Babak Sarani, Shahin Mohseni","doi":"10.1007/s00068-025-02775-0","DOIUrl":"10.1007/s00068-025-02775-0","url":null,"abstract":"<p><strong>Purpose: </strong>Frailty has gained recognition as a crucial determinant of patient outcomes following traumatic spinal injury (TSI), particularly due to its increasing incidence in elderly populations. The aim of the current investigation was therefore to compare the ability of several frailty scores to predict adverse outcomes in surgically managed isolated TSI patients without spinal cord injury.</p><p><strong>Methods: </strong>All adult patients (18 years or older) who suffered an isolated TSI due to blunt trauma, and required surgical management, were extracted from the 2013-2021 Trauma Quality Improvement Program database. The ability of the Orthopedic Frailty Score (OFS), the Hospital Frailty Risk Score (HFRS), the 11-factor (11-mFI) and 5-factor (5-mFI) modified frailty index, as well as the Johns Hopkins Frailty Indicator to predict adverse outcomes was compared based on the area under the receiver-operating characteristic curve (AUC). Subgroup analyses were also performed on patients who were ≥ 65 years old and those who were injured due to a ground-level fall (GLF).</p><p><strong>Results: </strong>A total of 39,449 patients were selected from the TQIP database. The 5-mFI and 11-mFI outperformed all other frailty scores when predicting in-hospital mortality (5-mFI AUC: 0.73) (11-mFI AUC: 0.73), any complication (5-mFI AUC: 0.65) (11-mFI AUC: 0.65), and FTR (5-mFI AUC: 0.75) (11-mFI AUC: 0.75). Among the 14,257 geriatric patients, however, the OFS demonstrated the highest predictive ability for in-hospital mortality (AUC: 0.65). The OFS (AUC: 0.64) also performed on the same level as both the 5-mFI (AUC: 0.63) and the 11-mFI (AUC: 0.63) when predicting FTR in this population. Among the 9616 patients who were injured due to a GLF, the OFS performed on par with the 5-mFI and 11-mFI when predicting in-hospital mortality and FTR.</p><p><strong>Conclusion: </strong>Simpler scores like the 5-factor modified Frailty Index and Orthopedic Frailty Score outperform or perform on par with more complicated frailty scores when predicting mortality, complications, and failure-to-rescue in surgically managed isolated traumatic spinal injury patients without spinal cord injury, particularly among geriatric patients and those injured in a GLF.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"126"},"PeriodicalIF":1.9,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11880054/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143540646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Significantly increased bone volume in a critical-sized defect model in the rat animal model by transplantation of a stand-alone vascularized periosteal flap.
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2025-02-28 DOI: 10.1007/s00068-025-02770-5
Florian Wichlas, Maximilian Wenzel, Valeska Hofmann, Klemens Trieb, Amelie Deluca, Herbert Tempfer, Andrea Wagner, Andreas Traweger, Sascha Senck, Christian Deininger

Purpose: The repair of bony non-unions remains challenging and often requires graft material due to limited availability of autologous bone. The aim of this study was to investigate the potency of a stand-alone pedicled periosteal flap (PF) versus a ligated periosteal flap (PFx), an empty defect and a crossover group in terms of newly formed bone in a 5 mm critical-sized defect in the rat femur diaphysis.

Methods: The following 4 treatment groups were formed out of a total of 36 male Sprague Dawley rats: Pedicled periosteal flap, ligated periosteal flap, crossover (each n = 10) and empty defect group (n = 6). A prospective randomized plate osteosynthesis was performed. The periosteal flap was dissected along with the supplying vessel from the medial femoral condyle with the aid of magnifying glasses and fixed to the plate and to the defect with a suture. Regular radiographic and µ-CT examinations were performed to determine bone volume inside the defect, as well as descriptive histological examinations.

Results: Newly formed bone tissue was measured by Bone Volume / Tissue Volume. The significant highest ratio to the control group was detected in the PF group after 10 weeks (18.77%) compared to the crossover- (11.28%; p = 0.0436), the PFx- (10.98%; p = 0.0411), and the control group (10.47%; p = 0.0293). No relevant differences were found in the descriptive histological examination.

Conclusion: According to the observed results, bony healing of non-union defects can be supported with a pedicled periosteal flap. The superiority of the pedicled compared to the ligated periosteal flap suggests that the improved blood flow within the defect area is an essential component of the healing phase itself.

{"title":"Significantly increased bone volume in a critical-sized defect model in the rat animal model by transplantation of a stand-alone vascularized periosteal flap.","authors":"Florian Wichlas, Maximilian Wenzel, Valeska Hofmann, Klemens Trieb, Amelie Deluca, Herbert Tempfer, Andrea Wagner, Andreas Traweger, Sascha Senck, Christian Deininger","doi":"10.1007/s00068-025-02770-5","DOIUrl":"10.1007/s00068-025-02770-5","url":null,"abstract":"<p><strong>Purpose: </strong>The repair of bony non-unions remains challenging and often requires graft material due to limited availability of autologous bone. The aim of this study was to investigate the potency of a stand-alone pedicled periosteal flap (PF) versus a ligated periosteal flap (PFx), an empty defect and a crossover group in terms of newly formed bone in a 5 mm critical-sized defect in the rat femur diaphysis.</p><p><strong>Methods: </strong>The following 4 treatment groups were formed out of a total of 36 male Sprague Dawley rats: Pedicled periosteal flap, ligated periosteal flap, crossover (each n = 10) and empty defect group (n = 6). A prospective randomized plate osteosynthesis was performed. The periosteal flap was dissected along with the supplying vessel from the medial femoral condyle with the aid of magnifying glasses and fixed to the plate and to the defect with a suture. Regular radiographic and µ-CT examinations were performed to determine bone volume inside the defect, as well as descriptive histological examinations.</p><p><strong>Results: </strong>Newly formed bone tissue was measured by Bone Volume / Tissue Volume. The significant highest ratio to the control group was detected in the PF group after 10 weeks (18.77%) compared to the crossover- (11.28%; p = 0.0436), the PFx- (10.98%; p = 0.0411), and the control group (10.47%; p = 0.0293). No relevant differences were found in the descriptive histological examination.</p><p><strong>Conclusion: </strong>According to the observed results, bony healing of non-union defects can be supported with a pedicled periosteal flap. The superiority of the pedicled compared to the ligated periosteal flap suggests that the improved blood flow within the defect area is an essential component of the healing phase itself.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"121"},"PeriodicalIF":1.9,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Study of bone-tendon interface healing in an animal model using a synthetic scaffold and PRP. 利用合成支架和 PRP 在动物模型中研究骨-肌腱界面愈合。
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2025-02-28 DOI: 10.1007/s00068-025-02796-9
Xavier Llorens Martínez, Leonardo Ruiz Macarrilla, Sergi Rey-Viñolas, Miguel A Mateos-Timoneda, Elisabeth Engel, J M Mora Guix

Purpose: Biological matrices have been used to reinforce large rotator cuff tear repairs. However, rapid resorption and initial immune reactions presented challenges in clinical practice. This study evaluates whether a resorbable synthetic matrix (scaffold), used alone or with platelet-rich plasma (PRP), impacts repair processes at microscopic, ultrasound, and biomechanical levels in a rabbit model of induced tendon-bone interface injury.

Methods: An experimental study was performed on 24 rabbits. Two experimental groups (n = 12 each) and a control group (n = 24) were defined. In the first group (BioP), the internal gastrocnemius tendon was sectioned and repaired to bone using double-row sutures, reinforced with a PLC (poly-L-lactic-co-ε-caprolactone) and PLA (polylactic acid) scaffold. In the second group (BioP + PRP), autologous PRP was added to the repair. The control group received no scaffold or PRP. Euthanasia was performed at 8 weeks, followed by microscopic, ultrasound, and biomechanical evaluations.

Results: Microscopically, a granulomatous reaction limited to the foreign body was observed in both scaffold groups. The healing process was not altered in any group, showing good biocompatibility of the scaffold. Echographically, a greater sagittal diameter was observed in the group without PRP compared to the other groups. Biomechanically, no significant differences in rupture zones were found across groups, but the scaffold-only group required a higher maximum applied force before rupture.

Conclusions: At 8 weeks, using a degradable synthetic PLC and PLA scaffold as support at the bone-tendon interface did not significantly alter the normal repair process, showed echographic and biomechanical benefits, and PRP did not show additional benefits in our experimental model.

目的:生物基质已被用于加固大型肩袖撕裂修复术。然而,快速吸收和初期免疫反应给临床实践带来了挑战。本研究评估了可吸收合成基质(支架)单独使用或与富血小板血浆(PRP)一起使用是否会在诱导肌腱骨界面损伤的兔子模型中对显微镜、超声波和生物力学层面的修复过程产生影响:方法:对 24 只兔子进行了实验研究。方法:对 24 只兔子进行了实验研究,确定了两个实验组(每组 12 只)和一个对照组(24 只)。在第一组(BioP)中,腓肠肌内肌腱被切开,并用双排缝合线与骨修复,同时用 PLC(聚左旋乳酸-ε-己内酯)和 PLA(聚乳酸)支架加固。第二组(BioP + PRP)在修复中加入自体 PRP。对照组不使用支架或 PRP。8 周后进行安乐死,然后进行显微镜、超声波和生物力学评估:结果:显微镜下观察到,两组支架组都出现了局限于异物的肉芽肿反应。各组的愈合过程均无变化,表明支架具有良好的生物相容性。从回声图上看,与其他组相比,无 PRP 组的矢状面直径更大。从生物力学角度看,各组的断裂带无明显差异,但仅使用支架组在断裂前所需的最大作用力更大:结论:在我们的实验模型中,使用可降解的合成聚乳酸和聚乳酸支架作为骨-肌腱界面的支撑物在 8 周后并没有明显改变正常的修复过程,并显示出回声图和生物力学方面的优势,而 PRP 并没有显示出额外的优势。
{"title":"Study of bone-tendon interface healing in an animal model using a synthetic scaffold and PRP.","authors":"Xavier Llorens Martínez, Leonardo Ruiz Macarrilla, Sergi Rey-Viñolas, Miguel A Mateos-Timoneda, Elisabeth Engel, J M Mora Guix","doi":"10.1007/s00068-025-02796-9","DOIUrl":"https://doi.org/10.1007/s00068-025-02796-9","url":null,"abstract":"<p><strong>Purpose: </strong>Biological matrices have been used to reinforce large rotator cuff tear repairs. However, rapid resorption and initial immune reactions presented challenges in clinical practice. This study evaluates whether a resorbable synthetic matrix (scaffold), used alone or with platelet-rich plasma (PRP), impacts repair processes at microscopic, ultrasound, and biomechanical levels in a rabbit model of induced tendon-bone interface injury.</p><p><strong>Methods: </strong>An experimental study was performed on 24 rabbits. Two experimental groups (n = 12 each) and a control group (n = 24) were defined. In the first group (BioP), the internal gastrocnemius tendon was sectioned and repaired to bone using double-row sutures, reinforced with a PLC (poly-L-lactic-co-ε-caprolactone) and PLA (polylactic acid) scaffold. In the second group (BioP + PRP), autologous PRP was added to the repair. The control group received no scaffold or PRP. Euthanasia was performed at 8 weeks, followed by microscopic, ultrasound, and biomechanical evaluations.</p><p><strong>Results: </strong>Microscopically, a granulomatous reaction limited to the foreign body was observed in both scaffold groups. The healing process was not altered in any group, showing good biocompatibility of the scaffold. Echographically, a greater sagittal diameter was observed in the group without PRP compared to the other groups. Biomechanically, no significant differences in rupture zones were found across groups, but the scaffold-only group required a higher maximum applied force before rupture.</p><p><strong>Conclusions: </strong>At 8 weeks, using a degradable synthetic PLC and PLA scaffold as support at the bone-tendon interface did not significantly alter the normal repair process, showed echographic and biomechanical benefits, and PRP did not show additional benefits in our experimental model.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"124"},"PeriodicalIF":1.9,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Surgical strategy for chest wall reconstruction secondary to cardiopulmonary resuscitation versus post-traumatic.
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2025-02-28 DOI: 10.1007/s00068-025-02799-6
Corinna Carla Dobroniak, Valeska Lesche, Ulrike Olgemöller, Paula Beck, Wolfgang Lehmann, Christopher Spering
<p><strong>Purpose: </strong>In mechanically cardiopulmonary resuscitated (CPR) patients, chest compressions at the level of the 3rd to 5th rib on the sternum result in reproducibly similar injury patterns: parasternal osteochondral dissociation (OCS) on both sides in combination with a sternal fracture with or without an additional serial rib fracture in the anterolateral column (ALS). This injury biomechanically impairs physiological breathing, resulting in an inverse breathing pattern. Trauma patients, on the other hand, often show a mixed pattern depending on the location of the main energy. The aim of the study was to evaluate the surgical technique of chest wall reconstruction (CWR) using transsternal refixation of the 5th rib on both sides in combination with plate osteosynthesis of the sternum and to analyze its success in comparison to the surgical strategy of CWR in the context of a traumatic genesis.</p><p><strong>Method: </strong>Data acquisition was performed using medical records of a Level I Trauma Centre in Germany and compare patients with radiologically or clinically diagnosed flail chest as a result of cardiopulmonary mechanical resuscitation (CPR). The retrospective study included patients in the period 2018-2023 after surgical CWR. The patients were either post-CPR (n = 29; CPR) or trauma patients (n = 36; trauma). The collective was described and analyzed using the digital patient file, as well as data on ICU stay and duration of ventilation or conversion to assisted ventilation modes, reason for chest wall instability, time of surgery, length of stay and mortality. As a long-term follow-up, body plethysmography was analyzed comparatively. Primary endpoints were mean length of stay in ICU, time to surgery, ventilator dependency and mortality rate. Secondary endpoints were time to transfer to rehabilitation, ventilation disorders and long term outcome.</p><p><strong>Results: </strong>In the period 65 patients (48 m, 17w) were included, 29 of whom had been mechanically resuscitated (CPR), 36 formed to post-traumatic cohort (trauma). The CPR were significantly older (69 vs. 58 years; p-value 0.003). The duration from CPR to surgery was on average significantly longer than trauma to surgery (16.76 vs. 4.11 days). The mean length of stay in ICU were 30 days (trauma) and 45 days for CPR (significantly longer, p-value 0.0008). The mean duration of ventilation was 188 h for trauma and 593 h for CPR. Extubation or conversion to assisted, relevant de-escalating ventilation modes was possible in both groups after a mean of 38 h post-OP. Among the CPR patients, 4 died in hospital (hospital mortality: CPR 20.7% vs. trauma 5.6%), 7 (30%) were transferred to an early clinical rehabilitation and 10 were discharged to home or follow-up treatment. In the case of trauma, 5 (14.7%) were transferred to an early clinical rehabilitation and 20 were discharged to home or follow-up treatment. Bodyplethysmography 6 months after CPR / trauma showed no
{"title":"Surgical strategy for chest wall reconstruction secondary to cardiopulmonary resuscitation versus post-traumatic.","authors":"Corinna Carla Dobroniak, Valeska Lesche, Ulrike Olgemöller, Paula Beck, Wolfgang Lehmann, Christopher Spering","doi":"10.1007/s00068-025-02799-6","DOIUrl":"10.1007/s00068-025-02799-6","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;In mechanically cardiopulmonary resuscitated (CPR) patients, chest compressions at the level of the 3rd to 5th rib on the sternum result in reproducibly similar injury patterns: parasternal osteochondral dissociation (OCS) on both sides in combination with a sternal fracture with or without an additional serial rib fracture in the anterolateral column (ALS). This injury biomechanically impairs physiological breathing, resulting in an inverse breathing pattern. Trauma patients, on the other hand, often show a mixed pattern depending on the location of the main energy. The aim of the study was to evaluate the surgical technique of chest wall reconstruction (CWR) using transsternal refixation of the 5th rib on both sides in combination with plate osteosynthesis of the sternum and to analyze its success in comparison to the surgical strategy of CWR in the context of a traumatic genesis.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Method: &lt;/strong&gt;Data acquisition was performed using medical records of a Level I Trauma Centre in Germany and compare patients with radiologically or clinically diagnosed flail chest as a result of cardiopulmonary mechanical resuscitation (CPR). The retrospective study included patients in the period 2018-2023 after surgical CWR. The patients were either post-CPR (n = 29; CPR) or trauma patients (n = 36; trauma). The collective was described and analyzed using the digital patient file, as well as data on ICU stay and duration of ventilation or conversion to assisted ventilation modes, reason for chest wall instability, time of surgery, length of stay and mortality. As a long-term follow-up, body plethysmography was analyzed comparatively. Primary endpoints were mean length of stay in ICU, time to surgery, ventilator dependency and mortality rate. Secondary endpoints were time to transfer to rehabilitation, ventilation disorders and long term outcome.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;In the period 65 patients (48 m, 17w) were included, 29 of whom had been mechanically resuscitated (CPR), 36 formed to post-traumatic cohort (trauma). The CPR were significantly older (69 vs. 58 years; p-value 0.003). The duration from CPR to surgery was on average significantly longer than trauma to surgery (16.76 vs. 4.11 days). The mean length of stay in ICU were 30 days (trauma) and 45 days for CPR (significantly longer, p-value 0.0008). The mean duration of ventilation was 188 h for trauma and 593 h for CPR. Extubation or conversion to assisted, relevant de-escalating ventilation modes was possible in both groups after a mean of 38 h post-OP. Among the CPR patients, 4 died in hospital (hospital mortality: CPR 20.7% vs. trauma 5.6%), 7 (30%) were transferred to an early clinical rehabilitation and 10 were discharged to home or follow-up treatment. In the case of trauma, 5 (14.7%) were transferred to an early clinical rehabilitation and 20 were discharged to home or follow-up treatment. Bodyplethysmography 6 months after CPR / trauma showed no","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"122"},"PeriodicalIF":1.9,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870994/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology of myocardial injury in trauma patients: proposed phenotypes for future research.
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2025-02-28 DOI: 10.1007/s00068-025-02798-7
Jett Karolewski, Jodie-Kate Williams, Natasha Weaver, Simone Meakes, Karen Gane, Zsolt J Balogh

Purpose: To describe the epidemiology of myocardial injury in trauma patients, in doing so informing design for future multicentre prospective studies.

Method: A one-year retrospective study ending on 31/08/2023 was conducted at a Level-1 Trauma Centre. All adult trauma resuscitation patients with elevated Troponin serum concentration were included. Patient demographics, medical history, mechanism, injury severity, laboratory data, cardiac investigations, LOS, ICU admission and mortality were collected. Patients were categorised into three pragmatic groups based on the timing of their Troponin peak (Group1:<12 h; Group2:12-24 h; Group3:>24 h).

Results: From 1408 admissions, 97(7%) patients [Age:57(35,80); Male:71%; ISS:18(9-33); LOS:9(4,16.5); ICU:66%; Mortality:16.5%] had elevated Troponin. Group 1 [n = 37; Age:47(24,70); Male:76%; ISS:9(4,22); LOS:7(3,14); ICU:51%; Mortaliy:5.4%]; Group 2 [n = 32; Age:53.5(26,74); Male:78%; ISS:27(12.5,53.5); LOS:10(5,17); ICU:84%; Mortaliy:25%] and Group 3 [n = 28; Age:78(62,84); Male:57%; ISS:19(9.5,47.5); LOS:12.5(6,19.5); ICU:64%; Mortaliy:21%]. 64% of patients had thoracic injuries, which was consistent among the three groups. Group 3 had most frequent ECG (61%) and echocardiography (25%) findings.

Conclusion: Troponin elevation occurs in 7% of all trauma admissions and it identifies the seriously injured high-risk cohort. The timing of the maximum Troponin concentration seems to describe three distinct phenotypes. "Hyperacute" with most favourable outcomes, "Subacute" with severe trauma and tissue injury requiring major resource utilisation and associated with the highest mortality rate, and "Late" characterised by ECG and ECHO changes suggesting primary ischaemic cardiac pathology.

目的:描述创伤患者心肌损伤的流行病学,从而为未来多中心前瞻性研究的设计提供参考:方法:在一家一级创伤中心开展了一项为期一年的回顾性研究,研究于 2023 年 8 月 31 日结束。纳入了所有肌钙蛋白血清浓度升高的成人创伤复苏患者。研究收集了患者的人口统计学资料、病史、发病机制、受伤严重程度、实验室数据、心脏检查、住院时间、入住重症监护室时间和死亡率。根据肌钙蛋白达到峰值的时间将患者分为三组(第一组:24 小时):结果:在 1408 名入院患者中,97(7%)名患者[年龄:57(35,80);男性:71%;ISS:18(9-33);LOS:9(4,16.5);ICU:66%;死亡率:16.5%]的肌钙蛋白升高。第 1 组[n = 37;年龄:47(24,70);男性:76%;ISS:9(4,22);LOS:7(3,14);ICU:51%;死亡率:5.4%];第 2 组[n = 32;年龄:53.5(26,74);男性:78%;ISS:27(12.5,53.5);LOS:10(5,17);ICU:84%;死亡率:25%]和第三组[n = 28;年龄:78(62,84);男性:57%;ISS:19(9.5,47.5);LOS:12.5(6,19.5);ICU:64%;死亡率:21%]。64%的患者胸部受伤,这在三组中是一致的。第 3 组的心电图(61%)和超声心动图(25%)结果最为常见:结论:在所有入院的创伤患者中,有 7% 的患者会出现肌钙蛋白升高,它能识别出重伤的高危人群。肌钙蛋白浓度达到最高值的时间似乎描述了三种不同的表型。"超急性 "结果最理想;"亚急性 "创伤和组织损伤严重,需要大量资源,死亡率最高;"晚期 "以心电图和心动图变化为特征,提示原发性缺血性心脏病变。
{"title":"Epidemiology of myocardial injury in trauma patients: proposed phenotypes for future research.","authors":"Jett Karolewski, Jodie-Kate Williams, Natasha Weaver, Simone Meakes, Karen Gane, Zsolt J Balogh","doi":"10.1007/s00068-025-02798-7","DOIUrl":"10.1007/s00068-025-02798-7","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the epidemiology of myocardial injury in trauma patients, in doing so informing design for future multicentre prospective studies.</p><p><strong>Method: </strong>A one-year retrospective study ending on 31/08/2023 was conducted at a Level-1 Trauma Centre. All adult trauma resuscitation patients with elevated Troponin serum concentration were included. Patient demographics, medical history, mechanism, injury severity, laboratory data, cardiac investigations, LOS, ICU admission and mortality were collected. Patients were categorised into three pragmatic groups based on the timing of their Troponin peak (Group1:<12 h; Group2:12-24 h; Group3:>24 h).</p><p><strong>Results: </strong>From 1408 admissions, 97(7%) patients [Age:57(35,80); Male:71%; ISS:18(9-33); LOS:9(4,16.5); ICU:66%; Mortality:16.5%] had elevated Troponin. Group 1 [n = 37; Age:47(24,70); Male:76%; ISS:9(4,22); LOS:7(3,14); ICU:51%; Mortaliy:5.4%]; Group 2 [n = 32; Age:53.5(26,74); Male:78%; ISS:27(12.5,53.5); LOS:10(5,17); ICU:84%; Mortaliy:25%] and Group 3 [n = 28; Age:78(62,84); Male:57%; ISS:19(9.5,47.5); LOS:12.5(6,19.5); ICU:64%; Mortaliy:21%]. 64% of patients had thoracic injuries, which was consistent among the three groups. Group 3 had most frequent ECG (61%) and echocardiography (25%) findings.</p><p><strong>Conclusion: </strong>Troponin elevation occurs in 7% of all trauma admissions and it identifies the seriously injured high-risk cohort. The timing of the maximum Troponin concentration seems to describe three distinct phenotypes. \"Hyperacute\" with most favourable outcomes, \"Subacute\" with severe trauma and tissue injury requiring major resource utilisation and associated with the highest mortality rate, and \"Late\" characterised by ECG and ECHO changes suggesting primary ischaemic cardiac pathology.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"123"},"PeriodicalIF":1.9,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11870892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143522894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The distribution of lateral rib fractures: a validation and further development of the AO/OTA classification system in patients with fractures at the rib shaft.
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2025-02-23 DOI: 10.1007/s00068-025-02795-w
Johannes Groh, Florian Kern, Johannes Krause, Mario Perl, Stefan Schulz-Drost

Introduction: Rib fractures are prevalent and clinically significant injuries, often associated with thoracic trauma. Despite their frequency, the precise distribution and characteristics of rib shaft fractures remain underexplored. This study investigates the distribution, location, and classification of lateral rib fractures using the AO/OTA classification, focusing on fracture patterns and the relationship to neighbored ribs.

Methods: The study retrospectively analyzed 116 patients with 617 isolated rib fractures treated at a Level 1 trauma center over seven years. Using CT scans, fractures between the tubercle and osteochondral junction of the rib shaft were examined. Fracture type, dislocation, and location were categorized according to AO standards. The 116 patients underwent detailed statistical analysis to identify distribution patterns and correlations between fracture characteristics.

Results: The fractures predominantly occurred between the fifth and seventh ribs, with a focus in the anterolateral to lateral region (40°-69°). Type A fractures were more anteriorly located, while type B fractures and dislocations shifted posteriorly. A regression analysis confirmed the significance of fracture type and dislocation in determining fracture position. Moreover, fractures showed clustering patterns, with adjacent ribs more likely to be injured. A caudal shift in fracture density and localization from the cranial to the caudal thorax was also observed.

Discussion and conclusion: The findings validate the AO/OTA classification for rib fractures, highlighting the need for refined subsegmental divisions within the rib shaft for more precise clinical application. The study underscores the relationship between fracture location, type, and associated injuries, advocating for multicenter studies and a comprehensive classification system for thoracic trauma. This could enhance our understanding of injury patterns and inform treatment strategies.

{"title":"The distribution of lateral rib fractures: a validation and further development of the AO/OTA classification system in patients with fractures at the rib shaft.","authors":"Johannes Groh, Florian Kern, Johannes Krause, Mario Perl, Stefan Schulz-Drost","doi":"10.1007/s00068-025-02795-w","DOIUrl":"10.1007/s00068-025-02795-w","url":null,"abstract":"<p><strong>Introduction: </strong>Rib fractures are prevalent and clinically significant injuries, often associated with thoracic trauma. Despite their frequency, the precise distribution and characteristics of rib shaft fractures remain underexplored. This study investigates the distribution, location, and classification of lateral rib fractures using the AO/OTA classification, focusing on fracture patterns and the relationship to neighbored ribs.</p><p><strong>Methods: </strong>The study retrospectively analyzed 116 patients with 617 isolated rib fractures treated at a Level 1 trauma center over seven years. Using CT scans, fractures between the tubercle and osteochondral junction of the rib shaft were examined. Fracture type, dislocation, and location were categorized according to AO standards. The 116 patients underwent detailed statistical analysis to identify distribution patterns and correlations between fracture characteristics.</p><p><strong>Results: </strong>The fractures predominantly occurred between the fifth and seventh ribs, with a focus in the anterolateral to lateral region (40°-69°). Type A fractures were more anteriorly located, while type B fractures and dislocations shifted posteriorly. A regression analysis confirmed the significance of fracture type and dislocation in determining fracture position. Moreover, fractures showed clustering patterns, with adjacent ribs more likely to be injured. A caudal shift in fracture density and localization from the cranial to the caudal thorax was also observed.</p><p><strong>Discussion and conclusion: </strong>The findings validate the AO/OTA classification for rib fractures, highlighting the need for refined subsegmental divisions within the rib shaft for more precise clinical application. The study underscores the relationship between fracture location, type, and associated injuries, advocating for multicenter studies and a comprehensive classification system for thoracic trauma. This could enhance our understanding of injury patterns and inform treatment strategies.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"120"},"PeriodicalIF":1.9,"publicationDate":"2025-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11847753/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clavicle refractures after hardware removal: are there risk factors? A retrospective cohort study.
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2025-02-21 DOI: 10.1007/s00068-025-02794-x
Franziska Kessler, Yannik Kalbas, Jan Hambrecht, Victoria Wlach, Sascha Halvachizadeh, Roman Pfeifer, Hans-Christoph Pape, Felix Karl-Ludwig Klingebiel, Christian Hierholzer

Purpose: Removal of symptomatic hardware after fracture fixation is common, especially in patients with clavicle fracture. Yet, refracture after hardware removal is a relatively common complication in those patients. The aim of this study was to identify risk factors for clavicle refractures that could be influenced by the surgical treatment provided.

Methods: All patients from a level one trauma center from 2017 to 2022 were screened for eligibility. Inclusion criteria included hardware removal after plate osteosynthesis of the clavicle, age ≥ 18 years, and signed informed consent. Groups were stratified according to occurrence of refracture: no-refracture (NR) vs. refracture (R). Nearest-neighbor matching in a ratio of 5:1 was performed. Parameter investigated included baseline demographics, fracture characteristics and surgical treatment details. A subgroup analysis of only clavicle shaft fractures was performed.

Results: Sixty patients were included with 50 patients in Group NR and 10 in Group R. Baseline characteristics were comparable between the groups. A subgroup analysis on shaft fractures revealed that a significantly larger working length (number of empty screw holes adjacent to the fracture site) in Group NR (1.94 ± 0.85) compared to the refracture group (1.20 ± 0.92) (p = 0.042). Logistic regression yielded an inverse correlation with the number of empty screw holes to the fracture site and the occurrence of refractures (OR 0.369, 95% CI 0.132-0.873; p = 0.035). Time in situ, lag screw application, plate positioning and the total amount of screws did not affect either of the groups.

Conclusion: An increased working length in patients with clavicle shaft fractures might be a protective measure for occurrence of refractures after hardware removal.

{"title":"Clavicle refractures after hardware removal: are there risk factors? A retrospective cohort study.","authors":"Franziska Kessler, Yannik Kalbas, Jan Hambrecht, Victoria Wlach, Sascha Halvachizadeh, Roman Pfeifer, Hans-Christoph Pape, Felix Karl-Ludwig Klingebiel, Christian Hierholzer","doi":"10.1007/s00068-025-02794-x","DOIUrl":"10.1007/s00068-025-02794-x","url":null,"abstract":"<p><strong>Purpose: </strong>Removal of symptomatic hardware after fracture fixation is common, especially in patients with clavicle fracture. Yet, refracture after hardware removal is a relatively common complication in those patients. The aim of this study was to identify risk factors for clavicle refractures that could be influenced by the surgical treatment provided.</p><p><strong>Methods: </strong>All patients from a level one trauma center from 2017 to 2022 were screened for eligibility. Inclusion criteria included hardware removal after plate osteosynthesis of the clavicle, age ≥ 18 years, and signed informed consent. Groups were stratified according to occurrence of refracture: no-refracture (NR) vs. refracture (R). Nearest-neighbor matching in a ratio of 5:1 was performed. Parameter investigated included baseline demographics, fracture characteristics and surgical treatment details. A subgroup analysis of only clavicle shaft fractures was performed.</p><p><strong>Results: </strong>Sixty patients were included with 50 patients in Group NR and 10 in Group R. Baseline characteristics were comparable between the groups. A subgroup analysis on shaft fractures revealed that a significantly larger working length (number of empty screw holes adjacent to the fracture site) in Group NR (1.94 ± 0.85) compared to the refracture group (1.20 ± 0.92) (p = 0.042). Logistic regression yielded an inverse correlation with the number of empty screw holes to the fracture site and the occurrence of refractures (OR 0.369, 95% CI 0.132-0.873; p = 0.035). Time in situ, lag screw application, plate positioning and the total amount of screws did not affect either of the groups.</p><p><strong>Conclusion: </strong>An increased working length in patients with clavicle shaft fractures might be a protective measure for occurrence of refractures after hardware removal.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"118"},"PeriodicalIF":1.9,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11845419/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrating blockchain technology with artificial intelligence for the diagnosis of tibial plateau fractures.
IF 1.9 3区 医学 Q2 EMERGENCY MEDICINE Pub Date : 2025-02-21 DOI: 10.1007/s00068-025-02793-y
Yi Xie, Xiaoliang Chen, Huiwen Yang, Honglin Wang, Hong Zhou, Lin Lu, Jiayao Zhang, Pengran Liu, Zhewei Ye

Purpose: The application of artificial intelligence (AI) in healthcare has seen widespread implementation, with numerous studies highlighting the development of robust algorithms. However, limited attention has been given to the secure utilization of raw data for medical model training, and its subsequent impact on clinical decision-making and real-world applications. This study aims to assess the feasibility and effectiveness of an advanced diagnostic model that integrates blockchain technology and AI for the identification of tibial plateau fractures (TPFs) in emergency settings.

Method: In this study, blockchain technology was utilized to construct a distributed database for trauma orthopedics, images collected from three independent hospitals for model training, testing, and internal validation. Then, a distributed network combining blockchain and deep learning was developed for the detection of TPFs, with model parameters aggregated across multiple nodes to enhance accuracy. The model's performance was comprehensively evaluated using metrics including accuracy, sensitivity, specificity, F1 score, and the area under the receiver operating characteristic curve (AUC). In addition, the performance of the centralized model, the distributed AI model, clinical orthopedic attending physicians, and AI-assisted attending physicians was tested on an external validation dataset.

Results: In the testing set, the accuracy of our distributed model was 0.9603 [95% CI (0.9598, 0.9605)] and the AUC was 0.9911 [95% CI (0.9893, 0.9915)] for TPF detection. In the external validation set, the accuracy reached 0.9636 [95% CI (0.9388, 0.9762)], was slightly higher than that of the centralized YOLOv8n model at 0.9632 [95% CI (0.9387, 0.9755)] (p > 0.05), and exceeded the orthopedic physician at 0.9291 [95% CI (0.9002, 0.9482)] and radiology attending physician at 0.9175 [95% CI (0.8891, 0.9393)], with a statistically significant difference (p < 0.05). Additionally, the centralized model (4.99 ± 0.01 min) had shorter diagnosis times compared to the orthopedic attending physician (25.45 ± 1.92 min) and the radiology attending physician (26.21 ± 1.20 min), with a statistically significant difference (p < 0.05).

Conclusion: The model based on the integration of blockchain technology and AI can realize safe, collaborative, and convenient assisted diagnosis of TPF. Through the aggregation of training parameters by decentralized algorithms, it can achieve model construction without data leaving the hospital and may exert clinical application value in the emergency settings.

{"title":"Integrating blockchain technology with artificial intelligence for the diagnosis of tibial plateau fractures.","authors":"Yi Xie, Xiaoliang Chen, Huiwen Yang, Honglin Wang, Hong Zhou, Lin Lu, Jiayao Zhang, Pengran Liu, Zhewei Ye","doi":"10.1007/s00068-025-02793-y","DOIUrl":"https://doi.org/10.1007/s00068-025-02793-y","url":null,"abstract":"<p><strong>Purpose: </strong>The application of artificial intelligence (AI) in healthcare has seen widespread implementation, with numerous studies highlighting the development of robust algorithms. However, limited attention has been given to the secure utilization of raw data for medical model training, and its subsequent impact on clinical decision-making and real-world applications. This study aims to assess the feasibility and effectiveness of an advanced diagnostic model that integrates blockchain technology and AI for the identification of tibial plateau fractures (TPFs) in emergency settings.</p><p><strong>Method: </strong>In this study, blockchain technology was utilized to construct a distributed database for trauma orthopedics, images collected from three independent hospitals for model training, testing, and internal validation. Then, a distributed network combining blockchain and deep learning was developed for the detection of TPFs, with model parameters aggregated across multiple nodes to enhance accuracy. The model's performance was comprehensively evaluated using metrics including accuracy, sensitivity, specificity, F1 score, and the area under the receiver operating characteristic curve (AUC). In addition, the performance of the centralized model, the distributed AI model, clinical orthopedic attending physicians, and AI-assisted attending physicians was tested on an external validation dataset.</p><p><strong>Results: </strong>In the testing set, the accuracy of our distributed model was 0.9603 [95% CI (0.9598, 0.9605)] and the AUC was 0.9911 [95% CI (0.9893, 0.9915)] for TPF detection. In the external validation set, the accuracy reached 0.9636 [95% CI (0.9388, 0.9762)], was slightly higher than that of the centralized YOLOv8n model at 0.9632 [95% CI (0.9387, 0.9755)] (p > 0.05), and exceeded the orthopedic physician at 0.9291 [95% CI (0.9002, 0.9482)] and radiology attending physician at 0.9175 [95% CI (0.8891, 0.9393)], with a statistically significant difference (p < 0.05). Additionally, the centralized model (4.99 ± 0.01 min) had shorter diagnosis times compared to the orthopedic attending physician (25.45 ± 1.92 min) and the radiology attending physician (26.21 ± 1.20 min), with a statistically significant difference (p < 0.05).</p><p><strong>Conclusion: </strong>The model based on the integration of blockchain technology and AI can realize safe, collaborative, and convenient assisted diagnosis of TPF. Through the aggregation of training parameters by decentralized algorithms, it can achieve model construction without data leaving the hospital and may exert clinical application value in the emergency settings.</p>","PeriodicalId":12064,"journal":{"name":"European Journal of Trauma and Emergency Surgery","volume":"51 1","pages":"119"},"PeriodicalIF":1.9,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143472217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
European Journal of Trauma and Emergency Surgery
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