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INFLUENCE OF RADIOFREQUENCY ELECTROMAGNETIC FIELD RADIATION ON THE LIVER OF RATS 射频电磁场辐射对大鼠肝脏的影响
Pub Date : 2022-01-29 DOI: 10.52340/jecm.2022.731
I. Sikharulidze, Ts M Sumbadze, Mtvarisa Kordzaia
The modern development of civilization cannot be imagined without the constantly growing number of many devices that emit electromagnetic waves. Mobile phones as sources of electromagnetic field (EMF) belong to the low radio frequency range. All this is of great interest for studying the influence of radio frequencies as an artificially created environmental factor on the health of humans and other living organisms. According to an experimental study, the impact of this radio frequency range on the liver causes damage to this organ. In particular, histo-pathological, degenerative changes in the liver parenchyma, significant biochemical functional changes, oxidative stress, and genetic damage to hepatocytes were revealed. All this suggests that similar changes can occur in the human body, which is the subject of further research
如果没有不断增加的许多发射电磁波的设备,现代文明的发展是不可想象的。手机作为电磁场(EMF)的来源,属于低射频范围。所有这些对于研究无线电频率作为人为创造的环境因素对人类和其他生物健康的影响具有极大的意义。根据一项实验研究,这个无线电频率范围对肝脏的影响会对这个器官造成损害。特别是肝实质的组织病理、退行性改变、显著的生化功能改变、氧化应激和肝细胞的遗传损伤。所有这些都表明,类似的变化也会发生在人体中,这是进一步研究的主题
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引用次数: 0
THE FALL IN THE GERIATRIC POPULATION: EPIDEMIOLOGY AND PREVENTION 老年人口减少:流行病学和预防
Pub Date : 2022-01-29 DOI: 10.52340/jecm.2022.727
Tamar Dochviri, N. Chikhladze, N. Pitskhelauri, T. Dochviri
The article discusses the fall as a significant public health problem. According to the World Health Organization, approximately 37.3 million cases of medically related falls occur each year. Human age is one of the major risk factors. Along with the "aging" trend of the society, the number of elderly people is increasing. Consequently, the number of falls and traumatic injuries caused by it increases for this quota.In developed countries, special attention is paid to studying the epidemiological characteristics of the fall in the population aged 65 and older. Such attention is that it is possible to plan and implement various preventive measures specifically for the target group and develop relevant recommendations to improve quality of life.The fall is one of the most common geriatric syndromes that threatens the independent lifestyle of older people and is related not only to medical but also social and economic aspects. However, epidemiological data of the fall are not properly studied in developing countries, including Georgia.Therefore, to reduce the traumatic injuries caused by falls in Georgia, it is essential to conduct appropriate epidemiological studies, identify the most critical risk factors, raise public awareness, and develop and implement appropriate preventive measures.
这篇文章作为一个重大的公共卫生问题来讨论这个问题。根据世界卫生组织的数据,每年大约发生3730万例与医学有关的跌倒病例。人类年龄是主要的危险因素之一。随着社会的“老龄化”趋势,老年人的数量正在增加。因此,在这一配额中,摔伤和外伤的人数有所增加。在发达国家,特别注意研究65岁及以上人口下降的流行病学特征。这种注意是,有可能计划和执行专门针对目标群体的各种预防措施,并制定有关的建议,以改善生活质量。跌倒是威胁老年人独立生活方式的最常见的老年综合征之一,不仅与医学有关,而且与社会和经济方面有关。然而,在包括格鲁吉亚在内的发展中国家,对这一下降的流行病学数据没有进行适当的研究。因此,为了减少格鲁吉亚跌倒造成的创伤性伤害,必须进行适当的流行病学研究,确定最关键的风险因素,提高公众认识,并制定和实施适当的预防措施。
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引用次数: 0
MICROSTRUCTUAL FEATURES OF VEGETATIVE ORGANS OF ACONITUM NUSUTUM FISCH. EX REICHENB., AN ALKALOID-CONTAINING PLANT WIDESPREAD IN GEORGIA 乌头鱼营养器官的显微结构特征。REICHENB交货。一种广泛分布于格鲁吉亚的含生物碱的植物
Pub Date : 2022-01-29 DOI: 10.52340/jecm.2022.732
L. Kintsurashvili, K. Mchedlidze, M. Churadze, Jemal Aneli
Anatomical structure of the common in the forests and meadows of the Georgian subalpine zone plant - Aconitum nasutum Fisch. ex Reichenb - underground and aerial vegetative organs, rich in diterpene alkaloids, was studied. A set of diagnostic features has been established using the accepted microtechnical methods. The conductive system the axial organs of A. nasutum, root, twig and leaf stalk, has a separated collateral structure. Casparian strips are prominent in the root endoderma but no clearly expressed radial interaction with the conductive tissue is observed. The thickening of the inner membrane of the differentiated conductive vessels in the wood is circular-spiral and reticular. Basal cells of the epidermis of the twig are arranged in a stitched, linear, thistle-rhombic structure. The underlying curved-walled type cells of the upper and lower epidermis of the leaf are non-curved and stitched. Both in the epidermis of the twig and in the leaf-covering tissue, the buds are simple, anomocytic in appearance. The leaf of A. nasutum has a bifacial shape, dorso-ventral, hypostomatic structure, a conductive bundle has collateral structure, and conical shaped villi of the leaf are single-celled.
格鲁吉亚亚高山地带常见的森林和草甸植物-乌头的解剖结构。研究了富含二萜生物碱的地下和空中营养器官。使用公认的微技术方法建立了一套诊断特征。金针菇的传导系统由根、枝、叶柄等轴向器官组成,具有独立的侧枝结构。Casparian条带在根内胚层中很突出,但没有观察到与导电组织明确表达的径向相互作用。木材中分化的导电血管的内膜增厚呈圆螺旋状和网状。细枝表皮的基底细胞排列成针状线状蓟菱形结构。叶片上下表皮的下伏曲壁型细胞不弯曲,呈针状。在小枝表皮和叶面组织中,芽都是简单的,外观上是不规则的。叶为双面形,背腹状,下气孔结构,导束有侧枝结构,叶的圆锥形绒毛为单细胞绒毛。
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引用次数: 0
VITAMIN D STATUS AND ITS CORRELATION WITH COMMUNITY ACQUIRED PNEUMONIA SEVERITY IN CHILDREN 儿童维生素d水平及其与社区获得性肺炎严重程度的关系
Pub Date : 2022-01-29 DOI: 10.52340/jecm.2022.730
M. Jachvadze, K. Gogberashvili
To elucidate the role of vitamin D status on the outcome of pneumonia, we estimated the associations between vitamin D status and pneumonia severity in children. Material and Methods. A hospital based cross-sectional study was conducted in two hospitals. 97 children with community acquired pneumonia (CAP) aged 5-17 years were included in 3 research groups divided according vitamin D status. Vitamin D3 deficiency was defined as a level of serum vitamin D<20ng/ml. The history of the child’s illness and the results from the physical examination and laboratory/instrumental data were recorded in a standardized form. Oxygen saturation (SpO2), weight, and height were measured. Indicators of the severity of pneumonia for analysis were presence or absence of danger signs, hypoxemia, prolonged hospitalization, and ICU admission, consolidation on chest X-ray, high inflammatory markers. Statistics. Data analysis was performed using SPSS 18.0 (SPSS Inc., Chicago, IL, USA). The nonparametric tests were used to compare groups (Kruskal–Wallis and Mann–Whitney). Statistical significance was taken as p<0.05. Results. Children with 25(OH)D <20ng/ml had an increased risk for treatment failure and a longer duration compared with patients with levels ≥ 30ng/ml (p<0.001). Hypoxemia and respiratory distress syndrome were more common in vitamin D3 deficient patients (p<0.05). The leukocytosis was in positive correlation with vitamin D3 deficiency, but CRP level was not associated with the vitamin D3 status. Pneumonia cases with 25(OH)D level 20-30ng/ml to compare with vitamin D3 level > 30ng/ml cases did not show any significant differences in severity. Conclusion. Vitamin D deficiency (level < 20ng/ml) was associated with severity of CAP in children. There is not yet achieved any consensus about this question and the data from ongoing clinical trials are needed for better elucidation of this matter.
为了阐明维生素D水平在肺炎预后中的作用,我们估计了维生素D水平与儿童肺炎严重程度之间的关系。材料和方法。在两家医院进行了以医院为基础的横断面研究。97例5 ~ 17岁社区获得性肺炎(CAP)患儿按维生素D水平分为3组。维生素D3缺乏被定义为血清维生素D水平为30ng/ml的病例在严重程度上没有表现出任何显著差异。结论。维生素D缺乏(水平< 20ng/ml)与儿童CAP的严重程度相关。关于这个问题还没有达成任何共识,需要正在进行的临床试验的数据来更好地阐明这个问题。
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引用次数: 0
COVID-19 PANDEMICS AND UNCOVENTIONAL, ALTERNATIVE FORMS OF TEACHING – A NEW EDUCATIONAL REALITY 2019冠状病毒病大流行与非传统的替代教学形式——新的教育现实
Pub Date : 2022-01-29 DOI: 10.52340/jecm.2022.724
M. Shakarashvili, T. Jorbenadze, N. Khvichia., M. Jorbenadze
As a result of the COVID-19 pandemic, most public and private educational institutions have fully switched to online learning mode. This teaching system has some advantages and disadvantages, which should be considered by the training organizers and, if necessary, to adjust the learning process and develop appropriate recommendations. It is very important to study the experience of other countries, to protect the fundamental rights of all groups and to develop the digital skills of stakeholders.
受新冠肺炎疫情影响,大多数公立和私立教育机构已全面转向在线学习模式。这种教学体系有利有弊,培训组织者应该考虑到这一点,并在必要时调整学习过程并提出适当的建议。学习其他国家的经验、保护所有群体的基本权利和发展利益相关者的数字技能是非常重要的。
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引用次数: 0
STUDY OF LIPIDS AND SOME BIOLOGICALLY ACTIVE COMPOUNDS OF THE FLOWERS SAMBUCUS NIGRA GROWING IN GEORGIA 产自乔治亚州的黑参花脂质及部分生物活性物质的研究
Pub Date : 2022-01-29 DOI: 10.52340/jecm.2022.716
B. Kikalishvili, T. Sulakvelidze, M. Getia, M. Malania, D. Turabelidze
The goal of the research was to study flowers of Sambucus nigra L. for the content of lipids and some biologically active compounds. There was obtained sums of neutral and polar lipids from the investigated object with various percentage yield. There was established the basic classes of lipids in them, was determined some physical – chemical constants of them. By using the gas-chromatographic method analysis in the sum of neutral lipids quantitatively and qualitatively were identified saturated, unsaturated and poly-unsaturated fatty acids with the high percentage content some of them. In the sum of polar lipids qualitatively and quantitatively is established and determined phospholipids. On the basis of research is established some other biologically active compounds in the mentioned object – carotenoids and aminoacids. On the basis of received results the vegetable oil from the flowers of Sambucus nigra L. is rich in biologically active compounds, which gives the opportunity to use it in medical practice.
本研究的目的是研究黑参花的脂质和一些生物活性物质的含量。从所研究的对象中获得了中性脂和极性脂的数量,收率不同。建立了它们的基本脂类,测定了它们的一些物理化学常数。采用气相色谱法对中性脂质总量进行定量定性分析,鉴定出饱和脂肪酸、不饱和脂肪酸和多不饱和脂肪酸,其中部分脂肪酸含量较高。在极性脂质总和中定性定量地建立和测定了磷脂。在研究的基础上,确定了上述对象中其他一些生物活性化合物-类胡萝卜素和氨基酸。根据已有的研究结果,黑参花的植物油含有丰富的生物活性化合物,这为其在医学实践中的应用提供了机会。
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引用次数: 0
OBESITY IN CHILDREN AND ADOLESCENTS: PRE- AND PERINATAL RISKS 儿童和青少年肥胖:产前和围产期风险
Pub Date : 2022-01-29 DOI: 10.52340/jecm.2022.729
Lia Otiashvili, L. Zhorzholiani, R. Karseladze
The aim of the study was to study the pre- and perinatal risk factors for the development of overweight/obesity in the population of children aged 7 to 17 years.A case-control study was conducted in which 210 students participated. The case group included 84 students with a verified diagnosis of overweight/obesity, and the control group - 126 healthy children with normal weight. The results revealed the following statistically significant risk factors for pre- and perinatal risk factors for overweight/obesity: Short-lived (P-0.037) and large families (P-0.000), low education of mothers (P-0.035), eating disorders during pregnancy (P-0.009), gestational pregnancy (P<0.035), cesarean section (P<0.017) and artificial feeding (P-0,024).Knowledge of pre- and perinatal risk factors is important to achieve targeted prevention of overweight/obesity in children.
该研究的目的是研究7至17岁儿童超重/肥胖的产前和围产期危险因素。对210名学生进行了病例对照研究。病例组包括84名确诊为超重/肥胖的学生,对照组包括126名体重正常的健康儿童。结果显示,产前和围产期超重/肥胖的危险因素有统计学意义:寿命短(P-0.037)、家庭人口多(P-0.000)、母亲受教育程度低(P-0.035)、孕期饮食失调(P-0.009)、妊娠期妊娠(P<0.035)、剖宫产(P<0.017)、人工喂养(P- 0.024)。了解产前和围产期危险因素对于有针对性地预防儿童超重/肥胖非常重要。
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引用次数: 0
PANIC ATTACKS AND CANCER 惊恐发作和癌症
Pub Date : 2021-11-02 DOI: 10.52340/jecm.2021.614
S. Vashadze, M. Artmeladze
According to statistics number of patients suffering from cancer rise every year. Study was conducted in oncological center of Adjara. Shixan scale was used during research. Research involved 200 patient aged from 20 year to 75, from them 130 were female and 70 male. 45 of them had surgery for treatment of cancer,16-had chemotherapy trement,radiotherapy-14 and combined therapy-125,patients with lung cancer-6, breast cancer -22, skin cancer -16, gastric cancer 27,bladder cancer-24, ovarian cancer -35, uterus cancer-25, larynx cancer -15, prostate cancer-30. Symptoms were evaluated with use of Shixan scale and according to results: agitation levels higher then 30 points was normal and higher than 80 points was high. During panic disorder this level is in the range of 57 points. According to research panic attack happened 15-20 times in month in 55 female patients and 35 male patients .Rere (5-10 panic attack in month)in 25 female patient and 45 male patient. Feeling of unsuccessfulness was found in 75 female and 45 male patients.Social disorders were found in 75 female and 22 male patients. Change in level of willingness in 80 female and 35 male patients. According to this data ,one of the treatment priority of oncological patients is psychological support after diagnosis till the end of treatment. Psychological awareness of patient and his/her family members is significant factor of treatment. Cost free psychological rehabilitation centers on the base of oncoclinics should be established .Psychological rehabilitation and management of psychiatric disorders should be significant part of treatment process of patient with cancer.
据统计,患癌症的人数每年都在上升。研究在ajara肿瘤中心进行。研究采用石山量表。研究涉及200名年龄在20岁至75岁之间的患者,其中130名女性,70名男性。其中手术治疗癌症45例,化疗16例,放疗14例,联合治疗125例,肺癌6例,乳腺癌22例,皮肤癌16例,胃癌27例,膀胱癌24例,卵巢癌35例,子宫癌25例,喉癌15例,前列腺癌30例。使用世显量表对症状进行评估,根据结果:躁动水平高于30分为正常,高于80分为高。在恐慌症期间,这个水平在57分的范围内。研究发现,55例女性患者和35例男性患者每月发生15-20次惊恐发作,25例女性患者和45例男性患者每月发生5-10次惊恐发作。女性75例,男性45例。女性75例,男性22例。80名女性患者和35名男性患者的意愿水平变化。根据这些数据,肿瘤患者的治疗重点之一是诊断后的心理支持,直到治疗结束。患者及其家属的心理意识是治疗的重要因素。应在肿瘤门诊的基础上建立免费的心理康复中心。心理康复和精神障碍管理应成为癌症患者治疗过程的重要组成部分。
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引用次数: 0
ABOUT STROKE 关于中风
Pub Date : 2021-11-02 DOI: 10.52340/jecm.2021.615
S. Vashadze
250 patients with cerebral blood flow disorder were tested at Adjarian Oncocenter. Among them 114 female and 86 male. Patients were grouped according to scale of stroke , developed by National health Institute. Plasminogen Activator ( t-PA) was most effective during acute stroke . Hospitalization of patient should not be oriented only for treatment of stroke but also about identifying Risk factors. Multidisciplinary (doctors, physiotherapists, occupational therapist , psychologists, specialized nurses and social workers ) group should be involved in rehabilitation process, which is the key for managing stroke patients.
在阿贾利安肿瘤中心对250例脑血流障碍患者进行了检测。其中女性114人,男性86人。根据国家卫生研究所制定的中风量表对患者进行分组。纤溶酶原激活剂(t-PA)在急性脑卒中中最有效。患者住院治疗不应仅以治疗为导向,还应以识别危险因素为导向。多学科(医生,物理治疗师,职业治疗师,心理学家,专业护士和社会工作者)团体参与康复过程是管理脑卒中患者的关键。
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引用次数: 23
STROKE AND LEUKOCYTES 中风和白细胞
Pub Date : 2021-11-01 DOI: 10.52340/jecm.2021.612
S. Vashadze, M. Kekenadze
Our aim is to study interaction of cerebrovascular diseases and peripheral blood ,to find new methods for prevention of this diseases .Materials and methods. 100 people was taking part in this study, among them 55 was men and 45- women ,aged 18-75 year. They all where diagnosed with brain stroke at acute stage. One hour after stroke amount of neutrophils sharply rises (2-3 times more than norm) and it is directly linked to size of stroke . Because of that when lacunar ischemic stroke have had happened the amount of neutrophils is not raised, however when circulation syndrome is seen the amount of neutrophils sharply rises and it depends on size of stroke.
我们的目的是研究脑血管疾病与外周血的相互作用,寻找预防脑血管疾病的新方法。100人参加了这项研究,其中男性55人,女性45人,年龄在18-75岁之间。他们都在急性期被诊断为脑中风。脑卒中后1小时中性粒细胞数量急剧上升(高于正常值2-3倍),与脑卒中大小有直接关系。因此,当腔隙性缺血性中风发生时,中性粒细胞的数量不会增加,但当出现循环综合征时,中性粒细胞的数量急剧增加,这取决于中风的大小。
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引用次数: 0
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