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2020 27th National and 5th International Iranian Conference on Biomedical Engineering (ICBME)最新文献

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Automatic sleep stage classification based on Dreem headband’s signals 基于Dreem头带信号的自动睡眠阶段分类
Shahla Bakian Dogaheh, M. Hassan Moradi
In this paper, we propose a system to perform automatic sleep stage classification based on physiological signals acquired by Dreem Headband. These signals contain 4 EEG (FpZ-O1, FpZ-O2, FpZ-F7, F8-F7), 2 Pulse oximeter (Red & Infra-red), and 3 accelerometer channels (X, Y, Z). The dataset used in this study belongs to a challenge competition, namely as Challenge Data and is publicly available on their website. In this work, sleep stages have been scored according to the AASM standard. Features were extracted from the physiological signals after applying a preprocessing step. Each of the EEG and PPG’s features is falling into one of the three categories time, frequency, or entropy. Moreover, ancillary features were also extracted from the accelerometer signal. Extracted features were classified by using support vector machine (SVM), K-nearest neighbor and Random forest classifiers. Due to the class imbalance problem, stratified 5-fold cross-validation was performed in order to tune systems parameters. Results show that among the three models as mentioned above, Random Forest has the best performance for the 5-class classification with accuracy: 79.98± 0.70 and kappa 0.7234±0.0095. The proposed model shows promising results, thus the model can be implemented in Dreem headband to differentiate sleep stages efficiently and be used in clinical applications.
本文提出了一种基于Dreem Headband采集的生理信号进行睡眠阶段自动分类的系统。这些信号包含4个EEG (FpZ-O1, FpZ-O2, FpZ-F7, F8-F7), 2个脉搏血氧仪(红色和红外线)和3个加速度计通道(X, Y, Z)。本研究使用的数据集属于一个挑战竞赛,即挑战数据,并在其网站上公开。在这项工作中,睡眠阶段按照AASM标准进行评分。对生理信号进行预处理后提取特征。EEG和PPG的每一个特征都属于时间、频率或熵这三个类别中的一个。此外,还从加速度计信号中提取了辅助特征。利用支持向量机(SVM)、k近邻(K-nearest neighbor)和随机森林分类器对提取的特征进行分类。由于类别不平衡问题,为了调整系统参数,进行了分层的5倍交叉验证。结果表明,在上述三种模型中,Random Forest在5类分类中表现最好,准确率为79.98±0.70,kappa为0.7234±0.0095。结果表明,该模型可以在Dreem头带中实现,有效地区分睡眠阶段,可用于临床应用。
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引用次数: 1
A Two-Stage Deep Learning Scheme to Estimate Depth of Anesthesia from EEG Signals 基于脑电信号估计麻醉深度的两阶段深度学习方案
S. Afshar, R. Boostani
Controlling the depth of anesthesia (DOA) through long surgeries is a crucial issue, and inaccurate dosage of pain killer and other anesthetic agents may lead to awareness or comma. Nonetheless, the accurate monitoring of DOA by analyzing electroencephalography (EEG) is still a challenge. To mimic the bispectral index (BIS) this study presents a deep learning method, which receives two EEG channels (located on the forehead) and continuously predicts the BIS score. The proposed method consists of convolutional neural network (residual network) followed by a recurrent neural network (bidirectional long short-term memory). In addition, we compare the performance of the proposed network with conventional methods in terms of regression and classification errors. All of the models are applied to a big dataset contains 176 subjects. The proposed network outperforms the conventional methods with respect to the generalization and both errors.
在长时间手术中控制麻醉深度(DOA)是一个关键问题,止痛药和其他麻醉剂的剂量不准确可能导致意识或昏迷。然而,通过分析脑电图(EEG)来准确监测DOA仍然是一个挑战。为了模拟双谱指数(BIS),本研究提出了一种深度学习方法,该方法接收两个EEG通道(位于前额)并连续预测BIS评分。该方法由卷积神经网络(残差网络)和递归神经网络(双向长短期记忆)组成。此外,我们在回归和分类误差方面比较了所提出的网络与传统方法的性能。所有模型都应用于包含176个主题的大数据集。该网络在泛化和误差两方面都优于传统方法。
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引用次数: 1
Rapid prototyping of low-cost digital microfluidic devices using laser ablation 激光烧蚀低成本数字微流控器件的快速成型
Mohsen Annabestani, F. Esmaeili, Nooshin Orouji, Pouria Esmaeili-Dokht, M. Fardmanesh
In this paper, a simple, low-cost, and fast prototyping method is presented for digital microfluidics (DMFs) fabrication. In the proposed method, commercial Polymethyl methacrylate (PMMA) sheets are used as the substrate, and a desktop diode laser engraver has replaced photolithography for electrode patterning. The proposed maskless method is capable of forming the DMF electrodes with ~100µm spacing. Engraved patterns are filled with a conductive paste like Silver paste to form electrodes. A thin layer of Polydimethylsiloxane (PDMS) and Bio-Oil® are exploited as dielectric and hydrophobic layer, respectively. Fabricated devices were successfully tested for droplet manipulation and mixing which shows that this method can be a rapid and low-cost alternative for conventional fabrication techniques.
本文提出了一种简单、低成本、快速的数字微流控制造方法。在提出的方法中,商用聚甲基丙烯酸甲酯(PMMA)片材用作衬底,桌面二极管激光雕刻机已取代光刻技术用于电极图案化。所提出的无掩模方法能够形成间距为~100 μ m的DMF电极。在雕刻的图案中填充一种导电浆料,如银浆料,形成电极。一层薄薄的聚二甲基硅氧烷(PDMS)和Bio-Oil®分别被用作介电层和疏水层。制备的装置成功地进行了液滴操纵和混合测试,这表明该方法可以作为传统制造技术的快速和低成本的替代方法。
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引用次数: 1
期刊
2020 27th National and 5th International Iranian Conference on Biomedical Engineering (ICBME)
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