Pub Date : 2022-12-02DOI: 10.1007/s12403-022-00525-w
V. Amiri, N. Sohrabi, Peiyue Li, Fahimeh Amiri
{"title":"Groundwater Quality for Drinking and Non-Carcinogenic Risk of Nitrate in Urban and Rural Areas of Fereidan, Iran","authors":"V. Amiri, N. Sohrabi, Peiyue Li, Fahimeh Amiri","doi":"10.1007/s12403-022-00525-w","DOIUrl":"https://doi.org/10.1007/s12403-022-00525-w","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2022-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42985722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-02DOI: 10.1007/s12403-022-00523-y
Hai Duc Nguyen, Hojin Oh, Min-Sun Kim
{"title":"Effect of Mixture of Heavy Metals on Metabolic Syndrome and Its Components in Individuals ≥ 18 Years of Age: From Big Data to Molecular Mechanisms Involved","authors":"Hai Duc Nguyen, Hojin Oh, Min-Sun Kim","doi":"10.1007/s12403-022-00523-y","DOIUrl":"https://doi.org/10.1007/s12403-022-00523-y","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2022-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43631391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01Epub Date: 2022-02-03DOI: 10.1007/s12403-022-00468-2
Margaret R Karagas, Susan McRitchie, Anne G Hoen, Cindy Takigawa, Brian Jackson, Emily R Baker, Juliette Madan, Susan J Sumner, Wimal Pathmasiri
In utero and early life exposure to inorganic arsenic (iAs) alters immune response in experimental animals and is associated with an increased risk of infant infections. iAs exposure is related to differences in the gut microbiota diversity, community structure, and the relative abundance of individual microbial taxa both in laboratory and human studies. Metabolomics permits a direct measure of molecular products of microbial and host metabolic processes. We conducted NMR metabolomics analysis on infant stool samples and quantified the relative concentrations of 34 known microbial-related metabolites. We examined these metabolites in relation to both in utero and infant log2 urinary total arsenic concentrations (utAs, the sum of iAs and iAs metabolites) collected at approximately 6 weeks of age using linear regression models, adjusted for infant sex, age at sample collection, type of delivery (vaginal vs. cesarean section), feeding mode (breast milk vs. any formula), and specific gravity. Increased fecal butyrate (b = 214.24), propionate (b = 518.33), cholate (b = 8.79), tryptophan (b= 14.23), asparagine (b = 28.80), isoleucine (b = 65.58), leucine (b = 95.91), malonate (b = 50.43), and uracil (b = 36.13), concentrations were associated with a doubling of infant utAs concentrations (p< 0.05). These associations were largely among infants who were formula fed. No clear associations were observed with maternal utAs and infant fecal metabolites. Metabolomic analyses of infant stool samples lend further evidence that the infant gut microbiota is sensitive to As exposure, and these effects may have functional consequences.
{"title":"Alterations in Microbial-Associated Fecal Metabolites in Relation to Arsenic Exposure Among Infants.","authors":"Margaret R Karagas, Susan McRitchie, Anne G Hoen, Cindy Takigawa, Brian Jackson, Emily R Baker, Juliette Madan, Susan J Sumner, Wimal Pathmasiri","doi":"10.1007/s12403-022-00468-2","DOIUrl":"10.1007/s12403-022-00468-2","url":null,"abstract":"<p><p>In utero and early life exposure to inorganic arsenic (iAs) alters immune response in experimental animals and is associated with an increased risk of infant infections. iAs exposure is related to differences in the gut microbiota diversity, community structure, and the relative abundance of individual microbial taxa both in laboratory and human studies. Metabolomics permits a direct measure of molecular products of microbial and host metabolic processes. We conducted NMR metabolomics analysis on infant stool samples and quantified the relative concentrations of 34 known microbial-related metabolites. We examined these metabolites in relation to both in utero and infant log<sub>2</sub> urinary total arsenic concentrations (utAs, the sum of iAs and iAs metabolites) collected at approximately 6 weeks of age using linear regression models, adjusted for infant sex, age at sample collection, type of delivery (vaginal vs. cesarean section), feeding mode (breast milk vs. any formula), and specific gravity. Increased fecal butyrate (<i>b</i> = 214.24), propionate (<i>b</i> = 518.33), cholate (<i>b</i> = 8.79), tryptophan (<i>b</i>= 14.23), asparagine (<i>b</i> = 28.80), isoleucine (<i>b</i> = 65.58), leucine (<i>b</i> = 95.91), malonate (<i>b</i> = 50.43), and uracil (<i>b</i> = 36.13), concentrations were associated with a doubling of infant utAs concentrations (<i>p<</i> 0.05). These associations were largely among infants who were formula fed. No clear associations were observed with maternal utAs and infant fecal metabolites. Metabolomic analyses of infant stool samples lend further evidence that the infant gut microbiota is sensitive to As exposure, and these effects may have functional consequences.</p>","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":"14 4","pages":"941-949"},"PeriodicalIF":6.7,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9918239/pdf/nihms-1818701.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10704067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-01Epub Date: 2022-02-02DOI: 10.1007/s12403-022-00469-1
Kristina M Zierold, John V Myers, Guy N Brock, Charlie H Zhang, Clara G Sears, Lonnie Sears
The prevalence of internalizing behavior disorders in children is increasing. Reasons for increasing anxiety and depression include several factors with a less studied consideration being the potential neurotoxic effects of environmental exposures. One group at risk for environmental exposures is children living near coal-burning power plants with coal ash storage facilities. Multivariate logistic regression was used to assess the relationship between metal(loid) exposures and internalizing behaviors in children aged 6-14 years. Metal(loid)s in nail samples were determined by Proton-Induced X-ray Emission and internalizing behavior problems were obtained from the parent ratings on the Child Behavior Checklist. Results indicated that concentrations of metal(loid)s in nails differ between children with internalizing behaviors and without internalizing behaviors. Logistic regression models suggested that exposure to zinc and imputed zirconium were associated with internalizing behaviors in children. However, when a sex-metal(loid) interaction term was included, none of the metal(loid)s were associated with internalizing behaviors indicating a role of sex differences in neurotoxicity with zinc and copper showing effects only for males. In all models, greater exposure to traffic was associated with internalizing behaviors. Zinc has previously been shown to increase risk for mental health problems, while zirconium has received less attention. Out findings indicate that environmental exposures of zinc and zirconium deserve further attention in studies of childhood internalizing disorders.
儿童内化行为障碍的发病率越来越高。焦虑和抑郁增加的原因包括多种因素，其中研究较少的是环境暴露对神经系统的潜在影响。生活在有煤灰储存设施的燃煤发电厂附近的儿童是环境暴露的高危人群之一。我们采用多变量逻辑回归法来评估 6-14 岁儿童的金属（loid）暴露与内化行为之间的关系。采用质子诱导 X 射线发射法测定指甲样本中的金属（loid）含量，并通过家长对儿童行为检查表的评分来了解儿童的内化行为问题。结果表明，有内化行为和无内化行为的儿童指甲中的金属（loid）浓度不同。逻辑回归模型表明，锌和锆的暴露与儿童的内化行为有关。然而，当加入性别-金属（loid）交互项时，没有一种金属（loid）与内化行为相关，这表明在神经毒性方面存在性别差异，锌和铜仅对男性有影响。在所有模型中，更多的交通接触与内化行为有关。锌曾被证明会增加精神健康问题的风险，而锆则较少受到关注。研究结果表明，在对儿童内化障碍的研究中，锌和锆的环境暴露值得进一步关注。
{"title":"Heavy Metal(loid) Body Burden in Environmentally Exposed Children With and Without Internalizing Behavior Problems.","authors":"Kristina M Zierold, John V Myers, Guy N Brock, Charlie H Zhang, Clara G Sears, Lonnie Sears","doi":"10.1007/s12403-022-00469-1","DOIUrl":"10.1007/s12403-022-00469-1","url":null,"abstract":"<p><p>The prevalence of internalizing behavior disorders in children is increasing. Reasons for increasing anxiety and depression include several factors with a less studied consideration being the potential neurotoxic effects of environmental exposures. One group at risk for environmental exposures is children living near coal-burning power plants with coal ash storage facilities. Multivariate logistic regression was used to assess the relationship between metal(loid) exposures and internalizing behaviors in children aged 6-14 years. Metal(loid)s in nail samples were determined by Proton-Induced X-ray Emission and internalizing behavior problems were obtained from the parent ratings on the Child Behavior Checklist. Results indicated that concentrations of metal(loid)s in nails differ between children with internalizing behaviors and without internalizing behaviors. Logistic regression models suggested that exposure to zinc and imputed zirconium were associated with internalizing behaviors in children. However, when a sex-metal(loid) interaction term was included, none of the metal(loid)s were associated with internalizing behaviors indicating a role of sex differences in neurotoxicity with zinc and copper showing effects only for males. In all models, greater exposure to traffic was associated with internalizing behaviors. Zinc has previously been shown to increase risk for mental health problems, while zirconium has received less attention. Out findings indicate that environmental exposures of zinc and zirconium deserve further attention in studies of childhood internalizing disorders.</p>","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":"14 1","pages":"903-914"},"PeriodicalIF":4.5,"publicationDate":"2022-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11185413/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41832258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hydrochemical Background Levels and Threshold Values of Phreatic Groundwater in the Greater Xi’an Region, China: Spatiotemporal Distribution, Influencing Factors and Implication to Water Quality Management","authors":"Yuhan Zhou, Jianhua Wu, Xingyu Gao, Wenyu Guo, Wenqian Chen","doi":"10.1007/s12403-022-00521-0","DOIUrl":"https://doi.org/10.1007/s12403-022-00521-0","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2022-11-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47716856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-12DOI: 10.1007/s12403-022-00517-w
Chalana M. Sol, S. Santos, K. Kannan, V. Jaddoe, L. Trasande
{"title":"Prenatal Exposure to Phthalates and Bisphenols and Childhood Kidney Function: A Prospective Cohort Study","authors":"Chalana M. Sol, S. Santos, K. Kannan, V. Jaddoe, L. Trasande","doi":"10.1007/s12403-022-00517-w","DOIUrl":"https://doi.org/10.1007/s12403-022-00517-w","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":"15 1","pages":"699-720"},"PeriodicalIF":6.7,"publicationDate":"2022-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47585477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-07DOI: 10.1007/s12403-022-00522-z
Hanghang Zhao, Peiyue Li, Xiaodong He, Jing Ning
{"title":"Microplastics Pollution and Risk Assessment in Selected Surface Waters of the Wei River Plain, China","authors":"Hanghang Zhao, Peiyue Li, Xiaodong He, Jing Ning","doi":"10.1007/s12403-022-00522-z","DOIUrl":"https://doi.org/10.1007/s12403-022-00522-z","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2022-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47848501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-29DOI: 10.1007/s12403-022-00518-9
C. McKernan, C. Meharg, M. Carey, A. Meharg
{"title":"The Dynamics of Selenium in Dairy Agroecosystems","authors":"C. McKernan, C. Meharg, M. Carey, A. Meharg","doi":"10.1007/s12403-022-00518-9","DOIUrl":"https://doi.org/10.1007/s12403-022-00518-9","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":" ","pages":""},"PeriodicalIF":6.7,"publicationDate":"2022-10-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45803440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-12DOI: 10.1007/s12403-022-00515-y
B. Du, Houhu Zhang, Dongliang Ji, Zhaoqin Huang, Fangqun Gan, Jun Zhou
{"title":"Environmental Contamination and Health Risk Assessment to Toxic Elements in an Active Lead–Zinc Mining Area","authors":"B. Du, Houhu Zhang, Dongliang Ji, Zhaoqin Huang, Fangqun Gan, Jun Zhou","doi":"10.1007/s12403-022-00515-y","DOIUrl":"https://doi.org/10.1007/s12403-022-00515-y","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":"15 1","pages":"687-698"},"PeriodicalIF":6.7,"publicationDate":"2022-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42138588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-10-11DOI: 10.1007/s12403-022-00516-x
E. Adomako, A. Raab, G. Norton, A. Meharg
{"title":"Potential Toxic Element (PTE) Soil Concentrations at an Urban Unregulated Ghanaian E-waste Recycling Centre: Environmental Contamination, Human Exposure and Policy Implications","authors":"E. Adomako, A. Raab, G. Norton, A. Meharg","doi":"10.1007/s12403-022-00516-x","DOIUrl":"https://doi.org/10.1007/s12403-022-00516-x","url":null,"abstract":"","PeriodicalId":12116,"journal":{"name":"Exposure and Health","volume":"15 1","pages":"677-686"},"PeriodicalIF":6.7,"publicationDate":"2022-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46647351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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