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Impact of a multifaceted intervention programme on antibiotic prescribing and dispensing in four patient-centred settings in five European countries. The HAPPY PATIENT project. 在五个欧洲国家的四个以病人为中心的环境中,多方面干预计划对抗生素处方和配药的影响。快乐病人 "项目。
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-07 DOI: 10.1093/fampra/cmae064
Ana García-Sangenís, Jesper Lykkegaard, Malene Plejdrup Hansen, Beatriz González López-Valcárcel, Fabiana Raynal, Laura Vallejo-Torres, Lars Bjerrum, Athina Chalkidou, Jette Nygaard Jensen, Ingrid Rebnord, Bent Håkan Lindberg, Katja Taxis, Maarten Lambert, Ruta Radzeviciene, Lina Jaruseviciene, Pia Touboul Lundgren, Pascale Bruno, Vanessa Lesage, Anna Kowalczyk, Maciej Godycki-Cwirko, Christos Lionis, Maria-Nefeli Karkana, Marilena Anastasaki, Matilde Bøgelund Hansen, Jonas Kanstrup Olsen, Jens Søndergaard, Daniela Modena, Stella Mally, Laura Álvarez, Carl Llor

Background: The primary cause of antimicrobial resistance is excessive and non-indicated antibiotic use.

Aim: To evaluate the impact of a multifaceted intervention aimed at various healthcare professionals (HCPs) on antibiotic prescribing and dispensing for common infections.

Design and setting: Before-and-after study set in general practice, out-of-hours services, nursing homes, and community pharmacies in France, Greece, Lithuania, Poland, and Spain.

Methods: Following the Audit Project Odense method, HCPs from these four settings self-registered encounters with patients related to antibiotic prescribing and dispensing before and after an intervention (February-April 2022 and February-April 2023). Prior to the second registration, the HCPs undertook a multifaceted intervention, which included reviewing and discussing feedback on the first registration's results, enhancing communication skills, and providing communication tools. Indicators to identify potentially unnecessary prescriptions and non-first-line antibiotic choices were developed, and the results of the two registrations were compared.

Results: A total of 345 HCPs registered 10 744 infections in the first registration period and 10 207 infections in the second period. In general practice, participants showed a significant 9.8% reduction in unnecessary antibiotic prescriptions in the second period, whereas limited or no effect was observed in out-of-hours services and nursing homes (0.8% reduction and 4.5% increase, respectively). Pharmacies demonstrated an 18% increase in safety checks, and correct advice in pharmacies rose by 17%.

Conclusion: External factors like COVID-19, antibiotic shortages, and a streptococcal epidemic impacted the intervention's benefits. Despite this, the intervention successfully improved antibiotic use in both settings.

背景:抗菌药耐药性的主要原因是抗生素的过度使用和不合理使用:目的:评估针对不同医疗保健专业人员(HCPs)的多方面干预措施对常见感染的抗生素处方和配药的影响:在法国、希腊、立陶宛、波兰和西班牙的全科诊所、非工作时间服务机构、疗养院和社区药房开展前后对比研究:方法:按照欧登塞审计项目的方法,这四个机构的保健医生在干预前后(2022 年 2 月至 4 月和 2023 年 2 月至 4 月)自行登记了与患者接触的抗生素处方和配药情况。在第二次登记之前,医疗保健人员进行了多方面的干预,包括回顾和讨论对第一次登记结果的反馈、提高沟通技巧和提供沟通工具。制定了识别潜在不必要处方和非一线抗生素选择的指标,并对两次登记的结果进行了比较:结果:共有 345 名初级保健人员在第一个登记期登记了 10 744 例感染,在第二个登记期登记了 10 207 例感染。在全科医生中,参与者在第二阶段大幅减少了 9.8%的不必要抗生素处方,而在非工作时间服务和疗养院中则效果有限或没有效果(分别减少了 0.8%和增加了 4.5%)。药房的安全检查增加了 18%,药房的正确建议增加了 17%:结论:COVID-19、抗生素短缺和链球菌流行等外部因素影响了干预措施的效益。结论:COVID-19、抗生素短缺和链球菌疫情等外部因素影响了干预措施的效益,尽管如此,干预措施仍成功改善了两种环境中的抗生素使用情况。
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引用次数: 0
Proper counseling for diagnosis and management of cannabinoid hyperemesis syndrome: a case report. 为诊断和处理大麻素分泌过多综合征提供适当咨询:一份病例报告。
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-07 DOI: 10.1093/fampra/cmae067
Samuel Cholette-Tétrault, Roland Grad

Background: Cannabinoid hyperemesis syndrome (CHS) is an increasingly recognized condition linked to chronic cannabis use, yet it remains frequently overlooked in clinical practice. The syndrome is characterized by cyclic episodes of severe nausea, vomiting, and abdominal pain, often relieved temporarily by hot showers or baths. With the rising prevalence of cannabis use following its legalization, the incidence of CHS has surged, presenting a significant challenge in both diagnosis and management within primary healthcare settings. Understanding the epidemiology, risk factors, and potential long-term sequelae of CHS is crucial for timely identification and intervention. This case report highlights the challenge of diagnosis and management of CHS in primary healthcare.

Objective(s): To emphasize the importance of proper counseling and the use of Rome IV criteria in diagnosing CHS. To illustrate how this may reduce patient suffering and unnecessary investigation.

Case: A 22-year-old female with chronic, daily cannabis use presented with recurrent episodes of intense nausea, vomiting, and abdominal pain over a 2-year period. Extensive diagnostic evaluations were inconclusive. A tentative diagnosis of CHS was made by a medical student and family doctor based on published criteria. The Rome IV criteria were then applied for confirmation of diagnosis and management. In so doing, the patient was advised to cease cannabis use for a minimum of 3 months. Initially, symptom improvement was reported with cannabis cessation. However, symptoms recurred following a relapse in cannabis use.

Conclusion: To confirm the diagnosis of CHS, counseling should specify the need for a minimum of 3 months of cannabis cessation to achieve symptom relief. Increased physician and patient awareness of this minimal time period for drug cessation can help to avoid unnecessary investigations, and prolonged patient suffering. This case emphasizes the need for vigilance in recognizing CHS and consideration of cannabis as a potential cause of cyclic vomiting.

背景:越来越多的人认识到,大麻素催吐综合征(CHS)与长期吸食大麻有关,但在临床实践中却经常被忽视。该综合征的特征是周期性发作的严重恶心、呕吐和腹痛,通常在热水淋浴或浸浴后可暂时缓解。随着大麻合法化后大麻使用率的上升,CHS 的发病率也随之激增,这给初级医疗机构的诊断和管理带来了巨大挑战。了解 CHS 的流行病学、风险因素和潜在的长期后遗症对于及时发现和干预至关重要。本病例报告强调了在基层医疗机构诊断和管理 CHS 所面临的挑战:目的:强调正确咨询和使用罗马 IV 标准诊断 CHS 的重要性。目的:强调正确咨询和使用罗马 IV 标准诊断 CHS 的重要性,说明如何减少患者痛苦和不必要的检查:病例:一名 22 岁女性,长期每天吸食大麻,两年来反复发作强烈恶心、呕吐和腹痛。广泛的诊断评估没有得出结论。一名医科学生和家庭医生根据已公布的标准做出了 CHS 的初步诊断。然后应用罗马 IV 标准进行确诊和治疗。为此,医生建议患者停止使用大麻至少 3 个月。据报告,停止吸食大麻后,最初的症状有所改善。然而,在重新吸食大麻后,症状再次出现:结论:要确诊慢性阻塞性肺病,咨询时应明确说明至少需要戒大麻 3 个月才能缓解症状。提高医生和患者对这一最短戒毒时间的认识有助于避免不必要的检查和延长患者的痛苦。本病例强调,需要警惕CHS的识别,并将大麻视为导致周期性呕吐的潜在原因。
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引用次数: 0
School absence policy and healthcare use: a difference-in-difference cohort analysis. 缺课政策与医疗保健的使用:差异队列分析。
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-02-07 DOI: 10.1093/fampra/cmae042
Kirsti Wahlberg, Kristine Pape, Bjarne Austad, Andreas Asheim, Kjartan S Anthun, Johan H Bjørngaard, Gunnhild Å Vie

Background: A national policy in Norway demanding certificates for medical absences in upper secondary school was implemented in 2016, leading to an increase in general practitioner (GP) visits in this age group.

Objectives: To assess the policy's effect on the use of primary and specialist healthcare.

Methods: A cohort study following all Norwegian youth aged 14-21 in the years 2010-2019 using a difference-in-differences approach comparing exposed cohorts expected to attend upper secondary school after the policy change in 2016 with previous unexposed cohorts. Data were collected from national registries.

Results: The absence policy led to the increased number of contacts with GPs for exposed cohorts during all exposed years, with estimated incidence rate ratios (IRRs) in the range from 1.14 (95% confidence intervals [CI] 1.11-1.18) to 1.25 (95% CI 1.21-1.30). Consultations for respiratory tract infections increased during exposed years. However, there was no conclusive policy-related difference in mental health consultations with GPs. In specialist healthcare we did not find conclusive evidence of an effect of absence policy on the risk of any contact per school year, but there was a slightly increased risk of contacts with ear-nose-throat specialist services.

Conclusions: We found an increase in general practice contacts attributable to the school absence policy. Apart from a possible increase in ear-nose-throat contacts, increased GP attention did not increase specialized healthcare.

背景挪威于2016年实施了一项要求高中生出具缺勤证明的国家政策,导致该年龄段的全科医生(GP)就诊率上升:评估该政策对使用初级和专科医疗服务的影响:对2010-2019年期间所有14-21岁的挪威青少年进行队列研究,采用 "差异中的差异 "方法,将2016年政策变化后预计将就读高中的受影响队列与之前未受影响的队列进行比较。数据来自国家登记处:缺课政策导致暴露人群在所有暴露年份中接触全科医生的次数增加,估计发病率比(IRR)在 1.14(95% 置信区间 [CI] 1.11-1.18] 到 1.25(95% CI 1.21-1.30)之间。在暴露年份,因呼吸道感染而就诊的人数有所增加。然而,在全科医生的心理健康咨询方面,并没有发现与政策相关的确凿差异。在专科医疗方面,我们没有发现缺课政策对每学年任何接触风险产生影响的确凿证据,但接触耳鼻喉专科服务的风险略有增加:结论:我们发现,缺课政策增加了全科医生的接诊次数。除了耳鼻喉科就诊人次可能增加外,全科医生关注度的提高并没有增加专科医疗服务的就诊人次。
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引用次数: 0
Recent life events and adverse childhood experiences in predicting antenatal depression and anxiety: cross-sectional study. 近期生活事件和不良童年经历预测产前抑郁和焦虑:横断面研究。
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-17 DOI: 10.1093/fampra/cmaf001
Benedicte M Zilmer, Gritt Overbeck, Volkert Siersma, Philip Wilson

Background: Antenatal depression and anxiety are associated with preterm labour, low birth weight, and postpartum depression, and can impact the emotional and mental development of the child. Both adverse childhood experiences and recent stressful events are linked to negative health outcomes. However, certain events may be more impactful than others.

Objective: This study aims to investigate the most important types of adverse childhood events and recent stressors that may help in identifying pregnant women in most need of psychological support.

Methods: This observational study examines data from the FamilieTrivsel trial, in which women between 6 and 10 weeks gestation were recruited by general practitioners. All participants were asked to complete questionnaires. Mental health was assessed with the Hospital Anxiety and Depression Score (HADS). Potential contributory risk factors were identified using the Recent Life Events Questionnaire and the Adverse Childhood Experiences questionnaire. The relative importance of the various types of events was analysed in a dominance analysis, and the direction of their association was determined by a multivariable linear regression analysis.

Results: Of specific recent life events, serious problems with a friend, divorce, racial harassment, unemployment, financial difficulties, and moving house had the strongest associations with poor mental health, along with childhood experience of mental illness in the household. Growing up with an experience of physical neglect and parental divorce were, paradoxically, associated with lower HADS scores.

Conclusions: Recent stressful life events have a stronger association with postnatal mental health than adverse childhood events, implying that it might be useful for clinicians providing routine antenatal care to gather information on recent stressors.

背景:产前抑郁和焦虑与早产、低出生体重和产后抑郁有关,并可影响儿童的情感和智力发育。不良的童年经历和最近的压力事件都与负面的健康结果有关。然而,某些事件可能比其他事件更有影响力。目的:本研究旨在探讨最重要的儿童不良事件类型和最近的压力源,可能有助于识别最需要心理支持的孕妇。方法:这项观察性研究检查了FamilieTrivsel试验的数据,在该试验中,全科医生招募了妊娠6至10周的妇女。所有参与者都被要求完成问卷调查。采用医院焦虑抑郁评分(HADS)评估心理健康状况。使用近期生活事件问卷和不良童年经历问卷来确定潜在的危险因素。在优势分析中分析了各种类型事件的相对重要性,并通过多变量线性回归分析确定了它们的关联方向。结果:在最近的具体生活事件中,与朋友的严重问题、离婚、种族骚扰、失业、经济困难和搬家与心理健康状况不佳以及家庭中儿童时期的精神疾病经历有着最强烈的联系。在身体被忽视和父母离婚的环境中长大的人,其高健康状况评分反而较低。结论:近期应激性生活事件与产后心理健康的相关性强于儿童期不良事件,这意味着临床医生提供常规产前护理时收集近期应激源的信息可能是有用的。
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引用次数: 0
'It's what we should be doing anyway': using financial incentives to promote relational continuity in Australian General Practice-a nested case study analysis. 无论如何,这是我们应该做的":利用经济激励促进澳大利亚全科医学的关系连续性--嵌套案例研究分析。
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-17 DOI: 10.1093/fampra/cmae071
Grant Russell, Susannah Westbury, Jenny Advocat, Nicholas Zwar, Christine Metusela, Marijka Batterham, Gregory M Peterson, Judy Mullan, Danielle Mazza, Jan Radford, Simon Eckermann, Andrew Bonney

Background: Relational continuity is a fundamental component of primary care. The 'Quality in General Practice Trial' (EQuIP-GP), was a 12-month cluster randomized trial, designed to investigate whether financial incentives can improve relational continuity in primary care.

Aim: To examine (i) how financial incentives are perceived and experienced by primary care patients, providers, and practice staff, and (ii) how clinical and organizational routines related to relational continuity are influenced by the introduction of a financial model designed to incentivize relational continuity.

Design and setting: We used a mixed methods case study approach with six of the intervention arm practices participating in the EQuIP-GP trial.

Method: Semi-structured interviews were conducted with patients, providers, practice staff, and intervention facilitators. Intervention facilitators kept structured diaries to capture reflective notes. To contextualize results, practices completed a modified practice attributes survey and patients completed the Primary Care Assessment Tool at baseline and 12 months.

Results: Patient-perceived relational continuity was not impacted by the intervention. Financial incentives were preferred for rewarding, as opposed to incentivizing, quality care; however, they were perceived as a blunt and inflexible instrument. The introduction of the incentive model increased attention to pre-existing organizational routines rather than creating new ones.

Conclusion: Incentive models should be suitably flexible to accommodate diversity in patient and practice needs. Small changes can be made to existing practice routines that will improve awareness and conscientiousness of relational continuity. Further research should examine how feasible these routine changes would be in practices that do not already focus on continuity.

背景:关系连续性是初级保健的基本组成部分。全科医疗质量试验"(EQuIP-GP)是一项为期 12 个月的分组随机试验,旨在研究经济激励措施能否改善全科医疗中的关系连续性。目的:研究(i)全科医疗患者、医疗服务提供者和医务人员如何看待和体验经济激励措施,以及(ii)与关系连续性相关的临床和组织常规如何受到旨在激励关系连续性的经济模式的影响:我们采用混合方法对参与 EQuIP-GP 试验的六家干预组诊所进行了案例研究:我们对患者、医疗服务提供者、诊所员工和干预促进者进行了半结构化访谈。干预促进者撰写了结构化日记,以记录反思性笔记。为了将结果具体化,在基线期和 12 个月时,医疗机构完成了修改后的医疗机构属性调查,患者完成了初级医疗评估工具:结果:患者认为的关系连续性没有受到干预的影响。与激励优质医疗服务相比,经济激励更受青睐;然而,经济激励被认为是一种钝化和缺乏灵活性的手段。激励模式的引入增加了对已有组织常规的关注,而不是创造新的常规:结论:激励模式应具有适当的灵活性,以适应患者和实践需求的多样性。可以对现有的诊疗常规进行微小的改动,以提高对关系连续性的认识和自觉性。进一步的研究应探讨这些常规改变在尚未注重连续性的实践中的可行性。
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引用次数: 0
Factors affecting cancer care delivery in primary care: a qualitative study. 影响初级保健中癌症护理提供的因素:一项定性研究。
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-17 DOI: 10.1093/fampra/cmae077
Dipesh P Gopal, Ping Guo, Stephanie J C Taylor, Nikolaos Efstathiou

Background: One role of primary care is to support people living with and beyond cancer, the number of whom is increasing worldwide. This study aimed to identify factors affecting cancer care provision within English primary care after the start of the coronavirus pandemic, during high healthcare service demand, and a depleted workforce.

Methods: An exploratory qualitative descriptive approach was used to collect data via remote semi-structured interviews with primary care staff after gaining informed consent. Interview transcripts were analysed using reflexive thematic analysis.

Results: Fifteen primary care staff were interviewed (11 general practitioners, 3 practice nurses, and 1 physician associate). Factors affecting cancer care delivery in primary care were: (i) patient level: acceptance of healthcare and understanding of cancer; (ii) clinician level: personal experience with cancer and knowledge; (iii) general practice level: care coordinators and cancer registers, and (iv) system level: lack of healthcare resourcing and political inaction.

Conclusions: The ability of primary care to deliver cancer care is affected by multiple factors at various levels. Future studies should identify the implementation strategies of local and national policies to better understand how to improve cancer care education, practice-level infrastructure, evidence-based workforce planning, and healthcare resourcing.

背景:初级保健的作用之一是为癌症患者提供支持,世界范围内癌症患者的数量正在增加。本研究旨在确定冠状病毒大流行开始后、医疗服务需求高、劳动力枯竭期间英国初级保健中影响癌症护理提供的因素。方法:在获得知情同意后,采用探索性定性描述性方法,通过与初级保健人员的远程半结构化访谈收集数据。访谈记录使用反身性主题分析进行分析。结果:访谈了15名基层医护人员(11名全科医生,3名执业护士,1名医师助理)。影响初级保健癌症护理提供的因素有:(i)患者水平:对医疗保健的接受程度和对癌症的了解;(ii)临床医生水平:个人癌症经验和知识;(iii)全科医生水平:护理协调员和癌症登记;(iv)系统水平:缺乏医疗资源和政治不作为。结论:初级保健提供癌症护理的能力受多种因素在不同水平上的影响。未来的研究应确定地方和国家政策的实施策略,以更好地了解如何改善癌症护理教育、实践水平的基础设施、循证劳动力规划和医疗保健资源。
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引用次数: 0
The Vulvodynia Primary Care Toolkit: results of a mixed-method evaluation with community-based family physicians in British Columbia. 外阴痛初级保健工具包:不列颠哥伦比亚省社区家庭医生混合方法评估的结果。
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-17 DOI: 10.1093/fampra/cmaf002
Katherine E Hunker, Melanie Altas, Kaitlyn M Goldsmith, Janine E Farrell, Katrina N Bouchard

Background: Healthcare providers often lack awareness, knowledge, and confidence in managing vulvodynia, which can lead to difficulties with diagnosis and treatment for individuals with the condition.

Objective: To develop and test an educational online toolkit tailored to supporting community-based primary care providers with diagnosis, treatment, and patient support for vulvodynia.

Methods: A sample of 19 community-based family physicians completed online surveys before and after testing the Vulvodynia Primary Care Toolkit (the toolkit hereafter) in their practice for 6 months. Nine physicians also completed a semi-structured interview to describe their experiences using the toolkit.

Results: The toolkit was adopted into clinical care, being used an average of 4.1 times per physician (SD = 2.7) during the test period. The toolkit demonstrated high acceptability, as evidenced by a high level of reported satisfaction with the toolkit and the amount of information it contained. The toolkit increased self-reported knowledge and confidence in diagnosing (P = .003), treating (P < .001), and supporting (P < .001) patients with vulvodynia. Through reflexive thematic analysis, we generated five themes from interview data that represented physicians' experiences: (i) There are facilitators and barriers to toolkit use in practice, (ii) the toolkit is valued by family physicians, (iii) the toolkit is educational, (iv) the toolkit is empowering, and (v) the toolkit improves vulvodynia management and referrals.

Conclusion: An online educational toolkit tailored to community-based primary care settings supports the management of patients with vulvodynia by family physicians. Our findings lay the foundation for the upscaling of this tool.

背景:医疗保健提供者往往缺乏认识,知识和信心,在管理外阴痛,这可能导致困难的诊断和治疗个人与条件。目的:开发和测试一个在线教育工具包,为社区初级保健提供者提供外阴痛的诊断、治疗和患者支持。方法:对19名社区家庭医生进行为期6个月的外阴痛初级保健工具包(以下简称工具包)测试前后的在线调查。九名医生还完成了一项半结构化的访谈,以描述他们使用工具包的经历。结果:该工具包被纳入临床护理,在测试期间平均每位医生使用4.1次(SD = 2.7)。该工具包显示了高可接受性,正如对工具包报告的高水平满意度及其包含的信息量所证明的那样。该工具包提高了外阴痛患者在诊断(P = 0.003)、治疗(P < 0.001)和支持(P < 0.001)方面的自我报告知识和信心。通过反身性主题分析,我们从访谈数据中生成了五个代表医生经验的主题:(i)在实践中使用工具包存在促进因素和障碍,(ii)工具包受到家庭医生的重视,(iii)工具包具有教育意义,(iv)工具包具有授权作用,(v)工具包改善外阴痛管理和转诊。结论:为社区初级保健机构量身定制的在线教育工具包支持家庭医生对外阴痛患者的管理。我们的发现为这一工具的升级奠定了基础。
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引用次数: 0
"I consider myself to be a leader": a qualitative exploration of early career women family physicians' intentions to assume a leadership role. "我认为自己是一名领导者":对职业生涯初期的女性家庭医生担任领导角色的意愿进行定性研究。
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-17 DOI: 10.1093/fampra/cmae070
Annie Koempel, Melissa K Filippi, Madeline Byrd, Anam Siddiqi, Andrew Bazemore, Yalda Jabbarpour

Background: Despite the increasing presence of women in US medical schools over the past 25 years, gender equity in medical leadership remains elusive. This qualitative study delves deeper into definitions of institutional leadership roles, who they are designed for, and how women currently contribute in unrecognized and uncompensated leadership positions.

Methods: We recruited family physicians who responded to the American Board of Family Medicine 2022 or 2023 graduate survey. We developed a semistructured interview guide following a modified life history approach to uncover women's experiences through the stages from residency to workforce. A qualitative researcher used Zoom to interview 25 geographically and racially diverse early career women physicians. Interviews were transcribed verbatim and analyzed utilizing NVivo software following an Inductive Content Analysis approach.

Results: Three themes emerged from the data. First, the nature of institutionally recognized leadership positions was largely perceived as bureaucratic and disciplinary, which did not appeal to most participants. Second, women engaged in leadership roles that increased practice efficiency, improved working conditions, and added to their emotional labor-without remuneration. Third, women experienced a tension between work and family, but this did not impact their long-term career goals-which remained focused on patient care or lower-level leadership positions.

Conclusion: Increasing the number of women in leadership positions can be achieved through innovative leadership models that prioritize collaboration, flexibility, and work-life balance. Organizations must revise definitions of leadership to expand it to include the valuable, unrewarded work women undertake that advance their goals and overall patient health.

背景:尽管在过去的25年里,美国医学院的女性人数不断增加,但医学领导中的性别平等仍然难以捉摸。这项定性研究深入探讨了机构领导角色的定义,这些角色是为谁设计的,以及女性目前如何在未被认可和无偿的领导职位上做出贡献。方法:我们招募了参与美国家庭医学委员会2022年或2023年毕业生调查的家庭医生。我们开发了一种半结构化的面试指南,遵循一种改进的生活史方法,揭示女性从住院医生到工作的各个阶段的经历。一位定性研究人员使用Zoom采访了25位地理和种族不同的早期职业女性医生。访谈被逐字记录下来,并利用NVivo软件按照归纳内容分析方法进行分析。结果:数据中出现了三个主题。首先,体制上认可的领导职位的性质在很大程度上被认为是官僚主义和纪律性的,这对大多数参与者没有吸引力。第二,女性担任领导角色,提高了实践效率,改善了工作条件,并增加了她们的情感劳动——没有报酬。第三,女性经历了工作和家庭之间的紧张关系,但这并不影响她们的长期职业目标——她们仍然专注于病人护理或较低层次的领导职位。结论:通过优先考虑协作、灵活性和工作与生活平衡的创新领导模式,可以增加女性担任领导职位的人数。组织必须修订领导力的定义,将其扩大到包括妇女从事的促进其目标和患者整体健康的有价值的、没有回报的工作。
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引用次数: 0
The benefits and harms of oral iron supplementation in non-anaemic pregnant women: a systematic review and meta-analysis. 非贫血孕妇口服补铁的利弊:一项系统综述和荟萃分析。
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-17 DOI: 10.1093/fampra/cmae079
Archie Watt, Holden Eaton, Kate Eastwick-Jones, Elizabeth T Thomas, Annette Plüddemann

Background: Iron deficiency during pregnancy poses a significant risk to both maternal and foetal health. Current international guidelines provide discrepant advice on antenatal iron supplementation for non-anaemic women.

Objective: We aimed to quantify the benefits and harms of routine antenatal supplementation in non-anaemic women.

Methods: The Cochrane Library, MEDLINE, Embase, and clinical trial registries were searched for randomized controlled trials and observational studies comparing oral iron supplementation with placebo or no supplement in non-anaemic pregnant women. Risk of bias was assessed for each study and the results were synthesized via meta-analysis.

Results: Twenty-three eligible studies were identified with 4492 non-anaemic pregnant women. Supplemented groups had higher haemoglobin [mean difference = 6.95 g/l, 95% confidence interval (CI): 4.81-9.09, P < .001, moderate certainty, I2 = 91%] and ferritin (mean difference = 12.22 ng/ml, 95% CI: 6.92-17.52, P < .001, moderate certainty, I2 = 87%) and were at lower risk of anaemia (relative risk = 0.50, 95% CI: 0.34-0.74, P < .001, high certainty, I2 = 42%, number needed to treat (NNT) = 10). There was no difference in birth weight, preterm birth, and rate of caesarean section. Reporting on harms was inconsistent and there was insufficient evidence to determine an association between iron supplements and any negative outcome.

Discussion: Prophylactic iron supplementation likely results in a large reduction in maternal anaemia during pregnancy. Future research should qualify the impact of this benefit on women's quality of life and determine which subpopulations benefit most. Evidence surrounding the harms of iron supplementation in the non-anaemic population is poor quality and inconsistent. Randomized controlled trials quantifying the risk of gastrointestinal (GI) disturbance and iron overload are essential to inform iron supplement use and reduce unwarranted variations in international guidelines.

背景:怀孕期间缺铁对孕产妇和胎儿健康都有重大风险。目前的国际指南对非贫血妇女的产前补铁提供了不同的建议。目的:我们旨在量化非贫血妇女常规产前补充的益处和危害。方法:检索Cochrane图书馆、MEDLINE、Embase和临床试验注册库,比较非贫血孕妇口服补铁与安慰剂或不补铁的随机对照试验和观察性研究。对每项研究进行偏倚风险评估,并通过荟萃分析对结果进行综合。结果:23项符合条件的研究纳入了4492名非贫血孕妇。补充组血红蛋白较高[平均差值= 6.95 g/l, 95%可信区间(CI): 4.81-9.09, P]讨论:预防性补充铁可能导致妊娠期间孕产妇贫血的大幅减少。未来的研究应确定这种益处对妇女生活质量的影响,并确定哪些亚群受益最大。关于在非贫血人群中补充铁的危害的证据质量差且不一致。量化胃肠道(GI)紊乱和铁超载风险的随机对照试验对铁补充剂的使用和减少国际指南中不必要的变化至关重要。
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引用次数: 0
Case control study of access to medications during COVID-19 and longitudinal impact on health outcomes for primary care patients managing multiple chronic conditions. COVID-19期间药物获取情况的病例对照研究及其对管理多种慢性病的初级保健患者健康结局的纵向影响
IF 2.4 4区 医学 Q1 MEDICINE, GENERAL & INTERNAL Pub Date : 2025-01-17 DOI: 10.1093/fampra/cmae074
Gail L Rose, Levi N Bonnell, Lisa W Natkin, Jennifer O'Rourke-Lavoie, Constance van Eeghen

Background: During coronavirus disease 2019 (COVID-19), people managing multiple chronic conditions (MCCs) experienced barriers to obtaining needed medications. The purposes of this paper are to (i) determine risk factors for difficulty obtaining medications during COVID-19, (ii) document reasons for the difficulty, and (iii) evaluate the impact on later physical and mental health outcomes.

Method: In a randomized controlled trial conducted in 2016-2021, 1969 adult primary care patients were surveyed about physical and mental health both before and during COVID-19. They reported their needs for medication during COVID-19 and any difficulty obtaining them. Reasons for difficulty accessing medications were tabulated descriptively. Logistic regression identified predictors of medication access difficulty. Multivariable linear regression modeled the relationship between access to medications and health outcomes, accounting for pre-COVID health.

Results: In total 13% of participants experienced difficulty accessing needed medications. Compared to the larger sample, those participants were younger, had more MCCs, and had lower income. They were more often female, unmarried, and were facing insecurities in housing, food, or finances (all P < 0.004). Younger age and the presence of socioeconomic insecurity at baseline increased the odds of later difficulty accessing medications. Barriers to access included concerns about contracting COVID-19 (52%), physician or pharmacy inaccessibility (38%), and cost (26%). Adjusting for baseline health, difficulty accessing medications was associated with poorer health at follow up (P = 0.001).

Conclusion: People with socioeconomic disadvantages experienced a disproportionate impact of difficulty obtaining medications and poorer health outcomes due to COVID-19. They may be at greater risk in the event of future pandemics and other societal disruptions.

背景:在2019冠状病毒病(COVID-19)期间,管理多种慢性疾病(mcs)的人在获得所需药物方面遇到了障碍。本文的目的是:(i)确定在COVID-19期间难以获得药物的风险因素,(ii)记录困难的原因,以及(iii)评估对后期身心健康结果的影响。方法:在2016-2021年进行随机对照试验,对1969例成人初级保健患者在COVID-19发生前和发生期间的身心健康状况进行调查。他们报告了他们在COVID-19期间对药物的需求以及获得药物的困难。对难以获得药物的原因进行了描述性列出。Logistic回归确定了药物获取困难的预测因素。多变量线性回归模拟了药物获取与健康结果之间的关系,并考虑了covid - 19前的健康状况。结果:总共有13%的参与者难以获得所需的药物。与更大的样本相比,这些参与者更年轻,有更多的mcc,收入更低。他们通常是女性,未婚,并且在住房,食物或财务方面面临不安全感(所有P结论:社会经济劣势的人因COVID-19而难以获得药物和较差的健康结果的影响不成比例。如果未来发生流行病和其他社会动乱,他们可能面临更大的风险。
{"title":"Case control study of access to medications during COVID-19 and longitudinal impact on health outcomes for primary care patients managing multiple chronic conditions.","authors":"Gail L Rose, Levi N Bonnell, Lisa W Natkin, Jennifer O'Rourke-Lavoie, Constance van Eeghen","doi":"10.1093/fampra/cmae074","DOIUrl":"10.1093/fampra/cmae074","url":null,"abstract":"<p><strong>Background: </strong>During coronavirus disease 2019 (COVID-19), people managing multiple chronic conditions (MCCs) experienced barriers to obtaining needed medications. The purposes of this paper are to (i) determine risk factors for difficulty obtaining medications during COVID-19, (ii) document reasons for the difficulty, and (iii) evaluate the impact on later physical and mental health outcomes.</p><p><strong>Method: </strong>In a randomized controlled trial conducted in 2016-2021, 1969 adult primary care patients were surveyed about physical and mental health both before and during COVID-19. They reported their needs for medication during COVID-19 and any difficulty obtaining them. Reasons for difficulty accessing medications were tabulated descriptively. Logistic regression identified predictors of medication access difficulty. Multivariable linear regression modeled the relationship between access to medications and health outcomes, accounting for pre-COVID health.</p><p><strong>Results: </strong>In total 13% of participants experienced difficulty accessing needed medications. Compared to the larger sample, those participants were younger, had more MCCs, and had lower income. They were more often female, unmarried, and were facing insecurities in housing, food, or finances (all P < 0.004). Younger age and the presence of socioeconomic insecurity at baseline increased the odds of later difficulty accessing medications. Barriers to access included concerns about contracting COVID-19 (52%), physician or pharmacy inaccessibility (38%), and cost (26%). Adjusting for baseline health, difficulty accessing medications was associated with poorer health at follow up (P = 0.001).</p><p><strong>Conclusion: </strong>People with socioeconomic disadvantages experienced a disproportionate impact of difficulty obtaining medications and poorer health outcomes due to COVID-19. They may be at greater risk in the event of future pandemics and other societal disruptions.</p>","PeriodicalId":12209,"journal":{"name":"Family practice","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142893388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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Family practice
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