Pub Date : 2025-02-20DOI: 10.1038/s41432-025-01127-6
Nicola Goodship, Greig Taylor
Nezhad H M, Ashourioun A, Sadeghdaghighi A The effect of virtual reality for anxiety and pain in dentistry: a systematic review and meta-analysis. Community Dent Health 2024; 41: 248–255. A systematic search was conducted across PubMed and Cochrane Library up to April 2024. The article type was limited to Randomised Controlled Trials, comparing virtual reality (VR) interventions with non-VR methods in dental settings. The selection followed the PRISMA-P guidelines. Using the PICOS framework, studies involving dental patients of any age utilising VR during dental treatments and reporting outcomes on anxiety and pain were included. Data extraction and quality appraisal were conducted independently by two reviewers using both the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) approach and the Risk of Bias 2 (ROB-2) tool. Meta-analyses used a random-effects model. A total of 263 studies resulted in the inclusion of 27 studies, encompassing several dental treatments. Evidence quality ranged from low to moderate. Meta-analysis of 14 studies, encompassing 957 patients, revealed VR significantly reduced anxiety in children (SMD −1.44, 95% CI −2.24 to −0.63, low quality of evidence). Metal-analysis of five studies (485 patients) revealed VR had no effect on adults’ anxiety (SMD -0.35, 95% CI -1.11 to 0.4, low level of certainty). VR significantly reduced pain in both children (11 studies, 791 participants) (SMD −1.11, 95% CI −1.65 to −0.57, moderate level of certainty) and adults (6 studies, 557 participants) (SMD −0.59, 95% CI −1.187 to −0.001, low evidence quality). Heterogeneity was high across studies. The study concluded that VR is a promising intervention for reducing anxiety and pain in children during dental procedures, and pain reduction in adults. The authors suggested further research is needed to standardise the VR content and explore its impact across different age groups and dental procedures.
相关评论:Nezhad H M, Ashourioun A, Sadeghdaghighi A 虚拟现实对牙科焦虑和疼痛的影响:系统综述和荟萃分析。Community Dent Health 2024; 41: 248-255.Data sources:截至 2024 年 4 月,在 PubMed 和 Cochrane 图书馆进行了系统检索:文章类型仅限于随机对照试验,比较牙科环境中的虚拟现实(VR)干预与非虚拟现实方法。选择遵循 PRISMA-P 指南。利用 PICOS 框架,纳入了涉及任何年龄段的牙科患者在牙科治疗过程中使用 VR 并报告焦虑和疼痛结果的研究:数据提取和质量评估由两名审稿人独立完成,他们同时使用了推荐、评估、发展和评价分级(GRADE)方法和偏倚风险2(ROB-2)工具。元分析采用随机效应模型:共有 263 项研究,最终纳入了 27 项研究,包括多种牙科治疗方法。证据质量从低到中等不等。对 14 项研究(包括 957 名患者)进行的元分析表明,VR 能显著减轻儿童的焦虑(SMD -1.44, 95% CI -2.24 to -0.63,证据质量低)。对五项研究(485 名患者)进行的金属分析表明,VR 对成年人的焦虑症没有影响(SMD -0.35,95% CI -1.11 至 0.4,证据确定性低)。VR 能明显减轻儿童(11 项研究,791 名参与者)和成人(6 项研究,557 名参与者)的疼痛(SMD -0.59,95% CI -1.187 -0.001,证据质量低)。不同研究之间的异质性很高:研究得出结论:VR 是一种很有前景的干预方法,可以减轻儿童在牙科治疗过程中的焦虑和疼痛,并减轻成人的疼痛。作者建议需要进一步研究,以标准化 VR 内容,并探索其对不同年龄组和牙科手术的影响。
{"title":"Can virtual reality reduce anxiety and pain in dental patients?","authors":"Nicola Goodship, Greig Taylor","doi":"10.1038/s41432-025-01127-6","DOIUrl":"10.1038/s41432-025-01127-6","url":null,"abstract":"Nezhad H M, Ashourioun A, Sadeghdaghighi A The effect of virtual reality for anxiety and pain in dentistry: a systematic review and meta-analysis. Community Dent Health 2024; 41: 248–255. A systematic search was conducted across PubMed and Cochrane Library up to April 2024. The article type was limited to Randomised Controlled Trials, comparing virtual reality (VR) interventions with non-VR methods in dental settings. The selection followed the PRISMA-P guidelines. Using the PICOS framework, studies involving dental patients of any age utilising VR during dental treatments and reporting outcomes on anxiety and pain were included. Data extraction and quality appraisal were conducted independently by two reviewers using both the Grading of Recommendations, Assessment, Development, and Evaluations (GRADE) approach and the Risk of Bias 2 (ROB-2) tool. Meta-analyses used a random-effects model. A total of 263 studies resulted in the inclusion of 27 studies, encompassing several dental treatments. Evidence quality ranged from low to moderate. Meta-analysis of 14 studies, encompassing 957 patients, revealed VR significantly reduced anxiety in children (SMD −1.44, 95% CI −2.24 to −0.63, low quality of evidence). Metal-analysis of five studies (485 patients) revealed VR had no effect on adults’ anxiety (SMD -0.35, 95% CI -1.11 to 0.4, low level of certainty). VR significantly reduced pain in both children (11 studies, 791 participants) (SMD −1.11, 95% CI −1.65 to −0.57, moderate level of certainty) and adults (6 studies, 557 participants) (SMD −0.59, 95% CI −1.187 to −0.001, low evidence quality). Heterogeneity was high across studies. The study concluded that VR is a promising intervention for reducing anxiety and pain in children during dental procedures, and pain reduction in adults. The authors suggested further research is needed to standardise the VR content and explore its impact across different age groups and dental procedures.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 1","pages":"59-60"},"PeriodicalIF":0.0,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41432-025-01127-6.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143467543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Five electronic databases (PubMed, Embase, Central, Web of Science, and Epistemonikos) and grey literature were systematically searched up to November 22, 2021 to identify studies relevant to patient-reported outcome measures (PROMs) in peri-implant soft tissue augmentation. Two authors independently reviewed the title, abstrac (screening phase), and full text (eligibility phase) of the articles after removing the duplicates, based on the pre-established inclusion criteria. A total of 29 clinical studies (19 randomized clinical trials, 7 non-randomized studies, and 3 case series) fulfilled the eligibility criteria based on the PICO framework. Data were independently extracted from the included studies by two authors using data extraction tables. The mean values of PROMs were pooled and analyzed with the weighted mean difference (WMD) and 95% confidence intervals (CIs) to summarize and compare the studies. Eleven subgroup meta-analyses (including 2–6 studies in each) were conducted using random-effect models to determine the differences in mean values of PROMs (pain scores on the Visual Analog Scale [VAS], analgesic consumption, satisfaction on VAS, aesthetic perception, surgery duration, and quality of life) between soft tissue autografts and substitutes. For mucosal thickness gain, pain perception was significantly reduced with soft tissue substitutes compared to subepithelial connective tissue graft (SCTG) at both 0–100 (n = 4; WMD = 14.91 VAS units; 95% CI: 6.42–23.40; P < 0.0006) and 0–10 VAS scale (n = 4; WMD = 1.62 VAS units; 95% CI: 0.01–3.23; P = 0.05). Similar results of significantly reduced pain with soft tissue substitutes on a 0–100 (n = 2; WMD = 21.43 VAS units; 95% CI: 12.58–30.28; P < 0.0001) and 0–10 VAS scale (n = 4; WMD = 1.65 VAS units; 95% CI: 0.66–2.64; P = 0.001) were found for keratinized tissue gain. Furthermore, with soft tissue substitutes painkiller consumption (n = 6; WMD = 1.56 tablets; 95% CI: 1.22–1.91; P < 0.00001) and surgery time (n = 5; WMD = 10.9 min; 95% CI: 4.60–17.19; P < 0.00001) were significantly less in comparison to autogenous grafts. Patient satisfaction, aesthetic perception, and quality of life did not differ significantly between soft tissue substitutes and autogenous grafts for soft tissue augmentation around implants. PROMs in terms of postoperative pain, analgesic intake, and surgery duration are significantly improved with the use of soft tissue substitutes for peri-implant soft tissue augmentation. Similar levels of patient satisfaction and aesthetic perception were achieved with soft tissue substitutes as with autogenous grafts, without impairing the clinical outcomes.
数据来源:系统检索截至2021年11月22日的5个电子数据库(PubMed、Embase、Central、Web of Science和Epistemonikos)和灰色文献,以确定与种植体周围软组织增强术中患者报告的结果测量(PROMs)相关的研究。研究选择:两位作者根据预先确定的纳入标准,在删除重复文献后,独立审查文章的标题、摘要(筛选阶段)和全文(合格阶段)。共有29项临床研究(19项随机临床试验,7项非随机研究和3例病例系列)符合基于PICO框架的入选标准。数据提取和综合:由两位作者使用数据提取表从纳入的研究中独立提取数据。采用加权平均差(WMD)和95%置信区间(ci)对PROMs的平均值进行汇总分析,总结比较研究结果。采用随机效应模型进行了11个亚组荟萃分析(每个亚组包括2-6个研究),以确定自体软组织移植物和替代品之间PROMs(视觉模拟量表[VAS]疼痛评分、镇痛药消耗、VAS满意度、美感、手术持续时间和生活质量)平均值的差异。结果:对于粘膜厚度增加,与上皮下结缔组织移植物(SCTG)相比,软组织替代物在0-100时的疼痛感知显著降低(n = 4;WMD = 14.91 VAS单位;95% ci: 6.42-23.40;P结论:使用软组织代用品进行种植体周围软组织隆胸,在术后疼痛、镇痛摄入、手术时间等方面均有明显改善。与自体移植物相比,软组织替代物获得了相似的患者满意度和美感水平,而不影响临床结果。
{"title":"Soft tissue substitutes improve patient-reported outcomes in peri-implant soft tissue augmentation","authors":"Vikender Singh Yadav, Kanika Makker, Anika Dawar, Aditi Nanda","doi":"10.1038/s41432-025-01121-y","DOIUrl":"10.1038/s41432-025-01121-y","url":null,"abstract":"Five electronic databases (PubMed, Embase, Central, Web of Science, and Epistemonikos) and grey literature were systematically searched up to November 22, 2021 to identify studies relevant to patient-reported outcome measures (PROMs) in peri-implant soft tissue augmentation. Two authors independently reviewed the title, abstrac (screening phase), and full text (eligibility phase) of the articles after removing the duplicates, based on the pre-established inclusion criteria. A total of 29 clinical studies (19 randomized clinical trials, 7 non-randomized studies, and 3 case series) fulfilled the eligibility criteria based on the PICO framework. Data were independently extracted from the included studies by two authors using data extraction tables. The mean values of PROMs were pooled and analyzed with the weighted mean difference (WMD) and 95% confidence intervals (CIs) to summarize and compare the studies. Eleven subgroup meta-analyses (including 2–6 studies in each) were conducted using random-effect models to determine the differences in mean values of PROMs (pain scores on the Visual Analog Scale [VAS], analgesic consumption, satisfaction on VAS, aesthetic perception, surgery duration, and quality of life) between soft tissue autografts and substitutes. For mucosal thickness gain, pain perception was significantly reduced with soft tissue substitutes compared to subepithelial connective tissue graft (SCTG) at both 0–100 (n = 4; WMD = 14.91 VAS units; 95% CI: 6.42–23.40; P < 0.0006) and 0–10 VAS scale (n = 4; WMD = 1.62 VAS units; 95% CI: 0.01–3.23; P = 0.05). Similar results of significantly reduced pain with soft tissue substitutes on a 0–100 (n = 2; WMD = 21.43 VAS units; 95% CI: 12.58–30.28; P < 0.0001) and 0–10 VAS scale (n = 4; WMD = 1.65 VAS units; 95% CI: 0.66–2.64; P = 0.001) were found for keratinized tissue gain. Furthermore, with soft tissue substitutes painkiller consumption (n = 6; WMD = 1.56 tablets; 95% CI: 1.22–1.91; P < 0.00001) and surgery time (n = 5; WMD = 10.9 min; 95% CI: 4.60–17.19; P < 0.00001) were significantly less in comparison to autogenous grafts. Patient satisfaction, aesthetic perception, and quality of life did not differ significantly between soft tissue substitutes and autogenous grafts for soft tissue augmentation around implants. PROMs in terms of postoperative pain, analgesic intake, and surgery duration are significantly improved with the use of soft tissue substitutes for peri-implant soft tissue augmentation. Similar levels of patient satisfaction and aesthetic perception were achieved with soft tissue substitutes as with autogenous grafts, without impairing the clinical outcomes.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 1","pages":"26-28"},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143425435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-13DOI: 10.1038/s41432-025-01118-7
Lydia Cross
A search of four databases (PubMed, EBSCOhost, Medline, and Google Scholar) identified studies for inclusion. Two reviewers independently selected articles for review. Studies published in English between January 2000 and June 2024 were selected. Studies that described the association of oral health and depression, and those with an oral health factor as the independent variable and depression as the dependent variable were eligible. Systematic reviews and case reports were excluded. Data was extracted from 31 eligible articles, which included both cross-sectional and prospective cohort studies, by two reviewers independently. The results of each study were narratively described; no meta-analysis was carried out due to heterogeneity between the studies. The authors reported that results were observed after controlling confounding factors. Each reviewer independently evaluated the studies’ methodological quality and validity using the Joanna Briggs Institute (JBI) tool for cross-sectional studies. There were mixed results regarding the impact of oral health on depression. Some studies reported significantly increased risk of depression with both tooth loss and oral pain, whilst others reported no association. Impaired oral function was consistently associated with symptoms of depression. The review concluded that oral health has a significant impact on depression and that there is a bi-directional relationship between the two, necessitating targeted interventions to improve oral health and thus positively impact mental health.
{"title":"Is depression influenced by oral health?","authors":"Lydia Cross","doi":"10.1038/s41432-025-01118-7","DOIUrl":"10.1038/s41432-025-01118-7","url":null,"abstract":"A search of four databases (PubMed, EBSCOhost, Medline, and Google Scholar) identified studies for inclusion. Two reviewers independently selected articles for review. Studies published in English between January 2000 and June 2024 were selected. Studies that described the association of oral health and depression, and those with an oral health factor as the independent variable and depression as the dependent variable were eligible. Systematic reviews and case reports were excluded. Data was extracted from 31 eligible articles, which included both cross-sectional and prospective cohort studies, by two reviewers independently. The results of each study were narratively described; no meta-analysis was carried out due to heterogeneity between the studies. The authors reported that results were observed after controlling confounding factors. Each reviewer independently evaluated the studies’ methodological quality and validity using the Joanna Briggs Institute (JBI) tool for cross-sectional studies. There were mixed results regarding the impact of oral health on depression. Some studies reported significantly increased risk of depression with both tooth loss and oral pain, whilst others reported no association. Impaired oral function was consistently associated with symptoms of depression. The review concluded that oral health has a significant impact on depression and that there is a bi-directional relationship between the two, necessitating targeted interventions to improve oral health and thus positively impact mental health.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 1","pages":"57-58"},"PeriodicalIF":0.0,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-13DOI: 10.1038/s41432-025-01119-6
Rajpal Tattar, Joshua Jackson, Richard Holliday
Electronic Nicotine Delivery Systems (ENDS, e-cigarettes) are a popular alternative to traditional tobacco smoking. Objective: To evaluate the effect of ENDS use on periodontal health. A protocol was published in accordance with PRISMA standards. Subjects with periodontal health, gingivitis and periodontitis were included. Reviews, case reports, letters, abstracts, narratives and expert opinions were excluded. Databases searched included PubMed, Embase, Web of Science, CINAHL Plus, and Dentistry & Oral Sciences Source up until February 2024. Risk of bias was evaluated using the Newcastle-Ottawa Scale, ROBINS-I and the RoB 2 tools. 40 eligible studies were included. Smokers had poorer clinical outcomes than ENDS users and non-smokers/former smokers, apart from bleeding on probing and gingival indices. There was no difference between ENDS users and non-smokers/former smokers in markers of periodontal destruction (pocket probing depths/marginal bone loss). ENDS users had higher plaque scores than non-smokers/former smokers. ENDS use leads to unique microbial changes compared to tobacco smokers and higher pro-inflammatory markers compared to non-smokers/former smokers. Within the limitations of the included studies which are at high risk of bias, we found evidence that ENDS use had some impact on periodontal parameters compared to non-smokers/former smokers. Tobacco smokers had consistently worst outcomes. CRD42024496560.
背景:电子尼古丁传递系统(ENDS,电子烟)是传统吸烟的一种流行替代品。目的:评价ENDS的使用对牙周健康的影响。方法:按照PRISMA标准发布治疗方案。研究对象包括牙周健康、牙龈炎和牙周炎患者。综述、病例报告、信函、摘要、叙述和专家意见被排除在外。检索的数据库包括PubMed, Embase, Web of Science, CINAHL Plus和Dentistry & Oral Sciences Source,截止到2024年2月。使用纽卡斯尔-渥太华量表、ROBINS-I和rob2工具评估偏倚风险。结果:纳入了40项符合条件的研究。除了牙诊和牙龈指数出血外,吸烟者的临床结果比ENDS使用者和非吸烟者/前吸烟者差。ENDS使用者与非吸烟者/前吸烟者在牙周破坏标志物(牙袋探测深度/边缘骨质流失)方面没有差异。ENDS使用者的斑块评分高于非吸烟者/前吸烟者。与吸烟者相比,终端的使用导致了独特的微生物变化,与非吸烟者/前吸烟者相比,终端的使用导致了更高的促炎标志物。结论:在纳入的高偏倚风险研究的局限性内,我们发现与非吸烟者/前吸烟者相比,使用ENDS对牙周参数有一定影响的证据。吸烟者的结果一直最糟糕。注册prospero 2024: crd42024496560。
{"title":"The impact of e-cigarette use on periodontal health: a systematic review and meta-analysis","authors":"Rajpal Tattar, Joshua Jackson, Richard Holliday","doi":"10.1038/s41432-025-01119-6","DOIUrl":"10.1038/s41432-025-01119-6","url":null,"abstract":"Electronic Nicotine Delivery Systems (ENDS, e-cigarettes) are a popular alternative to traditional tobacco smoking. Objective: To evaluate the effect of ENDS use on periodontal health. A protocol was published in accordance with PRISMA standards. Subjects with periodontal health, gingivitis and periodontitis were included. Reviews, case reports, letters, abstracts, narratives and expert opinions were excluded. Databases searched included PubMed, Embase, Web of Science, CINAHL Plus, and Dentistry & Oral Sciences Source up until February 2024. Risk of bias was evaluated using the Newcastle-Ottawa Scale, ROBINS-I and the RoB 2 tools. 40 eligible studies were included. Smokers had poorer clinical outcomes than ENDS users and non-smokers/former smokers, apart from bleeding on probing and gingival indices. There was no difference between ENDS users and non-smokers/former smokers in markers of periodontal destruction (pocket probing depths/marginal bone loss). ENDS users had higher plaque scores than non-smokers/former smokers. ENDS use leads to unique microbial changes compared to tobacco smokers and higher pro-inflammatory markers compared to non-smokers/former smokers. Within the limitations of the included studies which are at high risk of bias, we found evidence that ENDS use had some impact on periodontal parameters compared to non-smokers/former smokers. Tobacco smokers had consistently worst outcomes. CRD42024496560.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 2","pages":"117-118"},"PeriodicalIF":2.3,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12204857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-13DOI: 10.1038/s41432-025-01117-8
Rahul Mohandas, Subhashree Mohapatra
Benzydamine mouthwash is beneficial in avoiding radiation-induced oral mucositis (RIOM) in patients with head and neck cancer, but it is also expensive and has negative side effects, while herbal mouthwashes offer a potential, easily accessible alternative with less side effects and bioactive characteristics. Hence, the aim of the systematic review and network meta-analysis was to assess and compare the efficacy of herbal mouthwash and benzydamine mouthwash in preventing RIOM among head and neck cancer patients. After searching Scopus, PubMed, Cochrane, Science Direct, EBSCO Host, Lilacs, Science Direct, Web of Science, and Google Scholar from the earliest available year till July 15, 2024, 79 articles were obtained. Four full-text publications met the eligibility requirements and underwent additional processing for data extraction. PICO Strategy: P: Head and neck cancer patients, I: Herbal mouthwash, C: Benzydamine mouthwash, O: Reduction in radiation-induced oral mucositis. The review only comprised randomised controlled trials. The risk of bias assessment and quality of evidence were assessed using the RoB-2 Tool and GRADE Tool respectively. Curcumin mouthwash was most effective in reducing the incidence of oral mucositis followed by sumac-rose and turmeric mouthwash. Curcumin, turmeric, and sumac-rose mouthwashes were found to be effective in delaying the onset of oral mucositis as compared to the benzydamine group. Turmeric mouthwash followed by curcumin and sumac-rose mouthwash were found to be more effective in reducing the severity of oral mucositis. The current review concludes that curcumin, turmeric, and sumac-rose mouthwashes are more effective than benzydamine mouthwash in preventing RIOM. These natural alternatives show promising results for improving patient outcomes and should be investigated further to be used clinically. CRD42024570913
背景:苯胺漱口水有助于避免头颈癌患者的放射性口腔黏膜炎(RIOM),但它也很昂贵并且有副作用,而草药漱口水提供了一个潜在的,容易获得的替代品,副作用更小,生物活性更强。因此,本系统评价和网络荟萃分析的目的是评估和比较草药漱口水和苄胺漱口水在预防头颈癌患者RIOM的疗效。方法:检索Scopus、PubMed、Cochrane、Science Direct、EBSCO Host、Lilacs、Science Direct、Web of Science、谷歌Scholar等最早可查年份至2024年7月15日的论文79篇。四份全文出版物符合资格要求,并进行了额外的数据提取处理。PICO策略:P:头颈癌患者,I:草药漱口水,C:苄胺漱口水,O:减少放射性口腔黏膜炎。该综述仅包括随机对照试验。分别使用rob2工具和GRADE工具评估偏倚风险和证据质量。结果:姜黄素漱口水对降低口腔黏膜炎的发生率最有效,其次为紫苏玫瑰漱口水和姜黄漱口水。与苯胺组相比,姜黄素、姜黄和漆树玫瑰漱口水在延缓口腔黏膜炎发作方面被发现有效。姜黄漱口水,其次是姜黄素漱口水和漆树玫瑰漱口水,在减轻口腔黏膜炎的严重程度方面更有效。结论:姜黄素、姜黄、漆树玫瑰漱口水对RIOM的预防效果优于苄胺漱口水。这些天然替代品在改善患者预后方面显示出有希望的结果,应进一步研究以用于临床。普洛斯彼罗注册号:CRD42024570913。
{"title":"Comparative evaluation of the efficacy of herbal and benzydamine mouthwashes in preventing radiation-induced oral mucositis among head and neck cancer patients: a systematic review and network meta-analysis","authors":"Rahul Mohandas, Subhashree Mohapatra","doi":"10.1038/s41432-025-01117-8","DOIUrl":"10.1038/s41432-025-01117-8","url":null,"abstract":"Benzydamine mouthwash is beneficial in avoiding radiation-induced oral mucositis (RIOM) in patients with head and neck cancer, but it is also expensive and has negative side effects, while herbal mouthwashes offer a potential, easily accessible alternative with less side effects and bioactive characteristics. Hence, the aim of the systematic review and network meta-analysis was to assess and compare the efficacy of herbal mouthwash and benzydamine mouthwash in preventing RIOM among head and neck cancer patients. After searching Scopus, PubMed, Cochrane, Science Direct, EBSCO Host, Lilacs, Science Direct, Web of Science, and Google Scholar from the earliest available year till July 15, 2024, 79 articles were obtained. Four full-text publications met the eligibility requirements and underwent additional processing for data extraction. PICO Strategy: P: Head and neck cancer patients, I: Herbal mouthwash, C: Benzydamine mouthwash, O: Reduction in radiation-induced oral mucositis. The review only comprised randomised controlled trials. The risk of bias assessment and quality of evidence were assessed using the RoB-2 Tool and GRADE Tool respectively. Curcumin mouthwash was most effective in reducing the incidence of oral mucositis followed by sumac-rose and turmeric mouthwash. Curcumin, turmeric, and sumac-rose mouthwashes were found to be effective in delaying the onset of oral mucositis as compared to the benzydamine group. Turmeric mouthwash followed by curcumin and sumac-rose mouthwash were found to be more effective in reducing the severity of oral mucositis. The current review concludes that curcumin, turmeric, and sumac-rose mouthwashes are more effective than benzydamine mouthwash in preventing RIOM. These natural alternatives show promising results for improving patient outcomes and should be investigated further to be used clinically. CRD42024570913","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 2","pages":"118-118"},"PeriodicalIF":2.3,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143413829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The prospective observational study aimed to record the short-term patient-reported outcomes (PROMs) like pain, swelling, difficulty in mouth opening, and oral health quality of life (oral health impact profile-14), following a single-site tooth extraction and guided bone regeneration(GBR) using resorbable membrane and bone allograft. Correlation of PROMs with clinical/intra-surgical parameters like flap advancement, gingival and mucosal thickness, surgery duration, and wound opening were observed. PROMs and clinical parameters were assessed pre-operatively and on days 2,4,7 and 14 during the postoperative two weeks. Systemically healthy, non-smoker twenty-seven patients fulfilling the inclusion criteria of the dentate site with immediate post-extraction buccal dehiscence ≥4 mm were recruited. Only one tooth site from each patient was included in the study. The severity of pain, swelling, and difficulty in mouth opening were reported as zero, mild (1–3), moderate(4–6), and severe(7–10) using visual analog scores(VAS). The number of patients experiencing symptoms was presented as a percentage. Mean, standard error, median values, and IQR are reported for all OHIP-14 domains at various time points. Spearmen’s coefficient was used to correlate four PROMs for overall values for each time point separately and to correlate with clinical parameters. P < 0.05 was considered statistically significant. VAS for all PROMs peaked on post-surgical day 2 and improved until day 14. Most patients experienced no or mild symptoms during postoperative two weeks, with moderate to severe responses reported by 41–56% of patients on day 2. All PROMs correlated significantly with each other, with a strong correlation between VAS for pain and swelling. In the context of post-surgical oral health quality of life (OHIP-14), patients reported physical pain as the most experienced outcome, followed by psychological discomfort at all time points. All three PROMs pain, swelling, and difficulty of mouth opening positively correlated with all domains of OHIP-14, with the strongest correlation between the physical pain domain with VAS pain(day 7) and VAS swelling(day 2). Measured gingival thickness, mucosal thickness, flap advancement, and duration of surgery were 0.42 ± 0.04 mm, 0.2 ± 0.02 mm,6.8 ± 0.5 mm, and 123 ± 6 min, respectively. All clinical parameters and pre-operative PROMs correlated with post-operative PROMs. Wound opening was maximum on day 7 with an average extent of 3.3 mm and prevalence in 81.5%patients. Wound opening and duration of surgery were highly correlated with pain and flap advancement with difficulty of mouth opening on 7 th day. OHIP-14 was strongly associated with gingival thickness and wound healing on days 2 and 7, respectively. Short-term postoperative patient-reported outcomes are most severe on the second-day post-GBR. Clinical parameters like soft tissue thickness, flap advancement, and wound opening duration of surgery impact the PROMs like p
{"title":"Short-term patient-reported outcomes correlate with clinical parameters in guided bone regeneration","authors":"Anika Dawar, Vikender Singh Yadav, Aditi Nanda, Vandana Gupta","doi":"10.1038/s41432-025-01115-w","DOIUrl":"10.1038/s41432-025-01115-w","url":null,"abstract":"The prospective observational study aimed to record the short-term patient-reported outcomes (PROMs) like pain, swelling, difficulty in mouth opening, and oral health quality of life (oral health impact profile-14), following a single-site tooth extraction and guided bone regeneration(GBR) using resorbable membrane and bone allograft. Correlation of PROMs with clinical/intra-surgical parameters like flap advancement, gingival and mucosal thickness, surgery duration, and wound opening were observed. PROMs and clinical parameters were assessed pre-operatively and on days 2,4,7 and 14 during the postoperative two weeks. Systemically healthy, non-smoker twenty-seven patients fulfilling the inclusion criteria of the dentate site with immediate post-extraction buccal dehiscence ≥4 mm were recruited. Only one tooth site from each patient was included in the study. The severity of pain, swelling, and difficulty in mouth opening were reported as zero, mild (1–3), moderate(4–6), and severe(7–10) using visual analog scores(VAS). The number of patients experiencing symptoms was presented as a percentage. Mean, standard error, median values, and IQR are reported for all OHIP-14 domains at various time points. Spearmen’s coefficient was used to correlate four PROMs for overall values for each time point separately and to correlate with clinical parameters. P < 0.05 was considered statistically significant. VAS for all PROMs peaked on post-surgical day 2 and improved until day 14. Most patients experienced no or mild symptoms during postoperative two weeks, with moderate to severe responses reported by 41–56% of patients on day 2. All PROMs correlated significantly with each other, with a strong correlation between VAS for pain and swelling. In the context of post-surgical oral health quality of life (OHIP-14), patients reported physical pain as the most experienced outcome, followed by psychological discomfort at all time points. All three PROMs pain, swelling, and difficulty of mouth opening positively correlated with all domains of OHIP-14, with the strongest correlation between the physical pain domain with VAS pain(day 7) and VAS swelling(day 2). Measured gingival thickness, mucosal thickness, flap advancement, and duration of surgery were 0.42 ± 0.04 mm, 0.2 ± 0.02 mm,6.8 ± 0.5 mm, and 123 ± 6 min, respectively. All clinical parameters and pre-operative PROMs correlated with post-operative PROMs. Wound opening was maximum on day 7 with an average extent of 3.3 mm and prevalence in 81.5%patients. Wound opening and duration of surgery were highly correlated with pain and flap advancement with difficulty of mouth opening on 7 th day. OHIP-14 was strongly associated with gingival thickness and wound healing on days 2 and 7, respectively. Short-term postoperative patient-reported outcomes are most severe on the second-day post-GBR. Clinical parameters like soft tissue thickness, flap advancement, and wound opening duration of surgery impact the PROMs like p","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 1","pages":"32-33"},"PeriodicalIF":0.0,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143406474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The study utilized records from the Department of Oral Implantology at Wuhan University (May 2020 to April 2021). A total of 366 participants with missing teeth requiring implant-supported rehabilitation were included. Records detailed patient demographics, clinical procedures, and postoperative experiences. Data were collected through telephonic follow-ups and questionnaires assessing pain, anxiety, discomfort, and adverse events. Participants were selected based on the need for dental implant placement and/or bone augmentation. Inclusion criteria included being over 18 years old, possessing basic communication skills, and providing consent. Patients with systemic diseases, acute oral infections, or contraindications to implant therapy were excluded. Secondary-stage surgeries and sites with prior augmentation or implant failure were also excluded. Variables such as age, gender, alcohol consumption, smoking status, periodontal status, surgical procedures, and postoperative complications were collected. Perception of pain, anxiety, and discomfort was measured using a numerical rating scale (NRS). Logistic regression identified predictors of discomfort severity and duration. Most participants reported mild or no pain (78.7%) and anxiety (89.7%) during surgery. Discomfort decreased significantly over time, with 57.7% reporting discomfort on day 1, 36.1% on day 3, and 0% by day 14. Alcohol consumption, pain perception during surgery, age, and bone augmentation procedures were key predictors of discomfort. Tailored care is recommended to enhance outcomes.
{"title":"Do patient and surgical factors predict postoperative discomfort in implant dentistry?","authors":"A. Selva Arockiam, Praveen Chandrashekaraiah, Ramya Shivananjan, Reshma Benzigar, Nithya Nandhini","doi":"10.1038/s41432-025-01122-x","DOIUrl":"10.1038/s41432-025-01122-x","url":null,"abstract":"The study utilized records from the Department of Oral Implantology at Wuhan University (May 2020 to April 2021). A total of 366 participants with missing teeth requiring implant-supported rehabilitation were included. Records detailed patient demographics, clinical procedures, and postoperative experiences. Data were collected through telephonic follow-ups and questionnaires assessing pain, anxiety, discomfort, and adverse events. Participants were selected based on the need for dental implant placement and/or bone augmentation. Inclusion criteria included being over 18 years old, possessing basic communication skills, and providing consent. Patients with systemic diseases, acute oral infections, or contraindications to implant therapy were excluded. Secondary-stage surgeries and sites with prior augmentation or implant failure were also excluded. Variables such as age, gender, alcohol consumption, smoking status, periodontal status, surgical procedures, and postoperative complications were collected. Perception of pain, anxiety, and discomfort was measured using a numerical rating scale (NRS). Logistic regression identified predictors of discomfort severity and duration. Most participants reported mild or no pain (78.7%) and anxiety (89.7%) during surgery. Discomfort decreased significantly over time, with 57.7% reporting discomfort on day 1, 36.1% on day 3, and 0% by day 14. Alcohol consumption, pain perception during surgery, age, and bone augmentation procedures were key predictors of discomfort. Tailored care is recommended to enhance outcomes.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 1","pages":"23-25"},"PeriodicalIF":0.0,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-05DOI: 10.1038/s41432-025-01114-x
Diego Marques da Silva, Filipe Castro, Bruno Martins, Javier Flores Fraile, Juliana Campos Hasse Fernandes, Gustavo Vicentis Oliveira Fernandes
The goal of this systematic review was to verify whether the gingival phenotype (thick or thin) could impact the dental implant survival rate by affecting the marginal bone. The search was carried out on PubMed/MedLine, PubMed Central, and B-On databases. The research question was: “Does gingival phenotype positively or negatively influence marginal bone loss around dental implants?” The inclusion criteria were: any clinical trial/study, comparative study, prospective or retrospective articles, systematic review that addressed at least a 1-year follow-up with an assessment of the marginal bone loss (MBL) around dental implants, articles that reported the gingival phenotype (thin or thick) and were published in the last 13 years. The exclusion criteria were narrative or other reviews, letters to the editor, and commentaries. Data extraction included the author’s name, year of publication, type of study, sample size, number of implants, method used, and outcomes presented. The extracted data was summarized and presented in the results section. Critical Appraisal tool in JBI Systematic Reviews was used to determine the possibility of bias. A total of 62 articles were found, but eight articles were relevant to compose this study. After deep evaluation, it was possible to observe the implant success rate for both gingival phenotypes, thin and thick, was greater than 91% within a follow-up of up to 5 years. Therefore, it is unclear whether the thickness of the gingival tissue surrounding the implant can directly influence the marginal bone level. The gingival phenotype may be indirectly involved in the survival rate of dental implants, as it can be a risk factor for peri-implantitis, leading to marginal bone loss beyond what is expected. The thin gingival phenotype is one of the main risk factors for additional bone loss. It is crucial to know how to preserve the healthy condition. Within the results found, the gingival phenotype is indirectly related to implant survival rate and clinical parameters, which were respectively high and non-conclusive. Therefore, a higher risk of peri-implantitis is suggested when a thin phenotype is present.
{"title":"The influence of the gingival phenotype on implant survival rate and clinical parameters: a systematic review","authors":"Diego Marques da Silva, Filipe Castro, Bruno Martins, Javier Flores Fraile, Juliana Campos Hasse Fernandes, Gustavo Vicentis Oliveira Fernandes","doi":"10.1038/s41432-025-01114-x","DOIUrl":"10.1038/s41432-025-01114-x","url":null,"abstract":"The goal of this systematic review was to verify whether the gingival phenotype (thick or thin) could impact the dental implant survival rate by affecting the marginal bone. The search was carried out on PubMed/MedLine, PubMed Central, and B-On databases. The research question was: “Does gingival phenotype positively or negatively influence marginal bone loss around dental implants?” The inclusion criteria were: any clinical trial/study, comparative study, prospective or retrospective articles, systematic review that addressed at least a 1-year follow-up with an assessment of the marginal bone loss (MBL) around dental implants, articles that reported the gingival phenotype (thin or thick) and were published in the last 13 years. The exclusion criteria were narrative or other reviews, letters to the editor, and commentaries. Data extraction included the author’s name, year of publication, type of study, sample size, number of implants, method used, and outcomes presented. The extracted data was summarized and presented in the results section. Critical Appraisal tool in JBI Systematic Reviews was used to determine the possibility of bias. A total of 62 articles were found, but eight articles were relevant to compose this study. After deep evaluation, it was possible to observe the implant success rate for both gingival phenotypes, thin and thick, was greater than 91% within a follow-up of up to 5 years. Therefore, it is unclear whether the thickness of the gingival tissue surrounding the implant can directly influence the marginal bone level. The gingival phenotype may be indirectly involved in the survival rate of dental implants, as it can be a risk factor for peri-implantitis, leading to marginal bone loss beyond what is expected. The thin gingival phenotype is one of the main risk factors for additional bone loss. It is crucial to know how to preserve the healthy condition. Within the results found, the gingival phenotype is indirectly related to implant survival rate and clinical parameters, which were respectively high and non-conclusive. Therefore, a higher risk of peri-implantitis is suggested when a thin phenotype is present.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 2","pages":"119-119"},"PeriodicalIF":2.3,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12204858/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-02-05DOI: 10.1038/s41432-025-01113-y
Sundas Jamil
It has been proven that implants are predictable substitutes for replacing teeth. However, the effectiveness and survival of implants placed in sites previously affected by failure, as well as the optimal treatment strategies, remain poorly defined. This systematic review aimed to evaluate implant survival and peri-implant health in such cases, focusing on comparing immediate versus delayed implant placement and the role of augmentation. Four electronic databases were systematically searched, and meta-analyses were conducted with subgroup analyses (PROSPERO CRD42024548610). Of 1,798 records identified, 24 studies met the inclusion criteria. The 1-year survival rate for implants placed as replacements was 96.7% (95% CI: 92.8–99.3%). No significant differences were found between immediate and delayed placement (P = 0.31), or between immediate and delayed augmentation (P = 0.85). Although implants with immediate augmentation showed a higher survival rate (97.6%, 95% CI: 93.4–99.9%) compared to those with delayed augmentation (91.7%, 95% CI: 83.4–97.5%), this difference was not statistically significant (P = 0.26). Peri-implant health outcomes, including marginal bone loss, were consistent across subgroups. Replacing failed implants is often an attractive treatment option. While implants placed as replacements generally have lower survival rates compared to primary implants, immediate implant placement remains a viable option when adequate bone volume is present. The review supports the effectiveness of implant re-placement, with generally favourable. Dental implants are widely used for replacing missing teeth, but implant failure is a known complication. Understanding the outcomes of implants placed in sites where implants have failed is important as this situation can present challenges, such as insufficient bone or altered soft tissue conditions. This article provides data on the survival and health outcomes of implants placed in these failed sites, which may provide benefit to clinicians in these scenarios.
{"title":"Second chances for smiles: a systematic review of implants in failed sites","authors":"Sundas Jamil","doi":"10.1038/s41432-025-01113-y","DOIUrl":"10.1038/s41432-025-01113-y","url":null,"abstract":"It has been proven that implants are predictable substitutes for replacing teeth. However, the effectiveness and survival of implants placed in sites previously affected by failure, as well as the optimal treatment strategies, remain poorly defined. This systematic review aimed to evaluate implant survival and peri-implant health in such cases, focusing on comparing immediate versus delayed implant placement and the role of augmentation. Four electronic databases were systematically searched, and meta-analyses were conducted with subgroup analyses (PROSPERO CRD42024548610). Of 1,798 records identified, 24 studies met the inclusion criteria. The 1-year survival rate for implants placed as replacements was 96.7% (95% CI: 92.8–99.3%). No significant differences were found between immediate and delayed placement (P = 0.31), or between immediate and delayed augmentation (P = 0.85). Although implants with immediate augmentation showed a higher survival rate (97.6%, 95% CI: 93.4–99.9%) compared to those with delayed augmentation (91.7%, 95% CI: 83.4–97.5%), this difference was not statistically significant (P = 0.26). Peri-implant health outcomes, including marginal bone loss, were consistent across subgroups. Replacing failed implants is often an attractive treatment option. While implants placed as replacements generally have lower survival rates compared to primary implants, immediate implant placement remains a viable option when adequate bone volume is present. The review supports the effectiveness of implant re-placement, with generally favourable. Dental implants are widely used for replacing missing teeth, but implant failure is a known complication. Understanding the outcomes of implants placed in sites where implants have failed is important as this situation can present challenges, such as insufficient bone or altered soft tissue conditions. This article provides data on the survival and health outcomes of implants placed in these failed sites, which may provide benefit to clinicians in these scenarios.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 1","pages":"17-18"},"PeriodicalIF":0.0,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
To verify the effectiveness of school-based interventions (SBI) aimed at reducing sugar-sweetened beverage (SSB) consumption among children to create or enhance public health initiatives. An important source of sugar consumption is SSBs, which are defined as any consumable non-alcoholic water-based beverage containing considerable amounts of free sugars. A growing number of people are using SSBs as their main source of sugar. Obesity and overweight in children and adolescents is a serious public health concern. The frequent consumption of excess amounts of SSBs is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. The majority of earlier studies have concentrated on the association between SSB intake and obesity, regulatory and policy initiatives on SSB purchase and consumption. Numerous behavioural interventions have been reported to target the reduction of sugary drink consumption among children; however, there is a lack of conclusive evidence regarding their effectiveness. We aimed to evaluate the effectiveness of SBI on the factors that influence the reduction of sugary beverage consumption in a school setting. Systematic review of school-based interventions involving children. The following databases were investigated: MEDLINE/PubMed, PsycINFO, CINAHL and EMBASE. A total of forty-seven studies were included in the review. Most of the studies were found to be of moderate quality. All of the interventions, irrespective of whether they targeted individuals, their environment or both, were effective in decreasing SSB consumption. School-based interventions have demonstrated encouraging outcomes in decreasing sugary soft drink intake among teenagers. Several recommendations are made to improve future studies. The included trials demonstrated a moderate quality of evidence, suggesting that educational and behavioural interventions yielded only a modest effect in reducing sugar-sweetened beverage (SSB) consumption.
{"title":"Effectiveness of school-based approaches for reduction of sugar and sugar-sweetened beverages in children: a systematic review and meta-analysis","authors":"Sneha Malhotra, Deepali Aggarwal, Bharathi M. Purohit, Rahul Morankar, Amrita Chawla, Ritu Duggal, Nilima Nilima, Upendra Singh Bhadauria, Manali Deb Barma, Harsh Priya","doi":"10.1038/s41432-024-01103-6","DOIUrl":"10.1038/s41432-024-01103-6","url":null,"abstract":"To verify the effectiveness of school-based interventions (SBI) aimed at reducing sugar-sweetened beverage (SSB) consumption among children to create or enhance public health initiatives. An important source of sugar consumption is SSBs, which are defined as any consumable non-alcoholic water-based beverage containing considerable amounts of free sugars. A growing number of people are using SSBs as their main source of sugar. Obesity and overweight in children and adolescents is a serious public health concern. The frequent consumption of excess amounts of SSBs is a risk factor for obesity, type 2 diabetes, cardiovascular disease and dental caries. The majority of earlier studies have concentrated on the association between SSB intake and obesity, regulatory and policy initiatives on SSB purchase and consumption. Numerous behavioural interventions have been reported to target the reduction of sugary drink consumption among children; however, there is a lack of conclusive evidence regarding their effectiveness. We aimed to evaluate the effectiveness of SBI on the factors that influence the reduction of sugary beverage consumption in a school setting. Systematic review of school-based interventions involving children. The following databases were investigated: MEDLINE/PubMed, PsycINFO, CINAHL and EMBASE. A total of forty-seven studies were included in the review. Most of the studies were found to be of moderate quality. All of the interventions, irrespective of whether they targeted individuals, their environment or both, were effective in decreasing SSB consumption. School-based interventions have demonstrated encouraging outcomes in decreasing sugary soft drink intake among teenagers. Several recommendations are made to improve future studies. The included trials demonstrated a moderate quality of evidence, suggesting that educational and behavioural interventions yielded only a modest effect in reducing sugar-sweetened beverage (SSB) consumption.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 2","pages":"113-113"},"PeriodicalIF":2.3,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}