Evidence-based dentistry最新文献

{"title":"Questionnaires related to Evidence-Based Practice applied to dentists, faculty members or dental students: a scoping review","authors":"Viviane Oliveira Prado, Carlos Flores-Mir, Magda Feres, Luciana Faria Sanglard, Rafaela Manente, Paulo Nelson-Filho, Murilo Fernando Neuppmann Feres","doi":"10.1038/s41432-025-01136-5","DOIUrl":"10.1038/s41432-025-01136-5","url":null,"abstract":"Numerous instruments have been suggested to analyze the essential Evidence-Based Dentistry (EBD) dimensions, but it is unclear whether they were comprehensive and validated appropriately. To investigate instruments that assess EBD-related dimensions. We included primary studies involving dentists, faculty members, or dental students at any level of professional career that described validation or translation/transcultural adaptation processes of EBD instruments or reported the application of such instruments. Searches were conducted at PubMed, Embase, Web of Science, and Scopus, along with manual searches in EBD journals, Google Scholar and reference lists. Descriptive data were collected and standardized in tables, and summarized. Fifty studies were included. The KACE (Knowledge, Attitudes, Access, and Confidence Evaluation) instrument demonstrated clarity, internal consistency, face validity, discriminant validity, and responsiveness, but neglected important dimensions such as EBD-related practices, patient benefits, barriers/facilitators, and willingness to learn and disseminate EBD practices. The modified Berlin questionnaire designed to measure perceived/actual knowledge, showed clarity, internal consistency, content validity, and discriminant validity, but lacked data on reproducibility, face validity, construct validity, and responsiveness. Other questionnaires, while broader, had significant limitations in reported reliability and validation. Although the KACE instrument and the modified Berlin questionnaire underwent relatively rigorous reliability and validation testing, they were considered insufficiently comprehensive. When analyzed together, other questionnaires were found to be relatively more comprehensive, but they exhibited more significant limitations regarding reported reliability and validation assessments. This suggests the need for a novel instrument that fulfills a more significant number of validation phases and EBD-related dimensions.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 3","pages":"148-149"},"PeriodicalIF":2.3,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Should clinicians recommend oscillating-rotating toothbrushes over sonic models for superior plaque and gingivitis control?","authors":"A. Selva Arockiam, P. Nithya Nandhini, Praveen Chandrashekaraiah, Reshma Benzigar, Ramya Shivananjan","doi":"10.1038/s41432-025-01143-6","DOIUrl":"10.1038/s41432-025-01143-6","url":null,"abstract":"Adam R, Grender J, Timm H, Qaqish J, Goyal C R. A randomized controlled trial evaluating a novel oscillating-rotating electric toothbrush versus a sonic toothbrush for plaque and gingivitis. Am J Dent 2025; 38: 3–8. The study was a rigorously designed, single-center, examiner-blinded, randomized controlled trial. It included adult participants presenting with clinical signs of gingivitis and visible plaque. Subjects were randomly assigned to use either an oscillating-rotating electric toothbrush or a high-end sonic electric toothbrush. Both groups brushed twice daily for four weeks using a standard sodium fluoride toothpaste. Gingival inflammation was evaluated using the Modified Gingival Index and the Gingival Bleeding Index. Plaque accumulation was assessed via the Rustogi Modification of the Navy Plaque Index. Data were collected at baseline, immediately after a single brushing session and after four weeks of consistent use. Participants were adults diagnosed with plaque-induced gingivitis. They were randomized into two arms: one group used the Oral-B iO2 toothbrush with the Ultimate Clean brush head in Daily Clean mode while the other group used the usmile Marble-Art toothbrush with the Advanced Whitening brush head in high-intensity clean mode. All participants followed a standardized brushing regimen. Examiner blinding was implemented to reduce observational bias and enhance objectivity. Gingival inflammation and plaque levels were assessed at three distinct intervals. The percentage of participants achieving gingival health defined as fewer than ten percent of bleeding sites was also measured. Comparisons were performed within and between groups. The threshold for statistical significance was set at a probability value less than 0.05. Both devices led to statistically significant reductions in plaque accumulation and gingival inflammation. However, the oscillating-rotating toothbrush demonstrated superior performance across all parameters. Participants using this toothbrush exhibited a significantly greater reduction in Modified Gingival Index scores and a marked decrease in the number of bleeding sites. A higher proportion of users in this group attained gingival health status. Plaque removal was more effective following a single brushing session with notable improvements observed throughout the entire mouth, interproximal surfaces and along the gingival margins. These benefits were maintained at the four-week follow-up. The oscillating-rotating toothbrush achieved superior clinical outcomes in the reduction of plaque and gingival inflammation when compared to the sonic toothbrush. Its efficacy was observed both immediately and after consistent use over a four-week period.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 2","pages":"99-100"},"PeriodicalIF":2.3,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143989810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biologic complications in short implant-assisted versus conventional partial dentures","authors":"Nidhi Parmar","doi":"10.1038/s41432-025-01140-9","DOIUrl":"10.1038/s41432-025-01140-9","url":null,"abstract":"Benzaquen S I, Ardakani M T, Tsigarida A et al. Biologic complications with removable partial dentures assisted by short implants: A 34-month pilot randomized controlled clinical trial. J Prosthet Dent 2025; https://doi.org/10.1016/j.prosdent.2025.01.026 . This single-centre, parallel-arm, pilot randomised controlled clinical trial (RCT) was conducted in accordance with CONSORT guidelines. The primary objective was to compare the incidence of biologic complications between conventional removable partial dentures (CRPDs) and short implant-assisted removable partial dentures (IARPDs) in patients with Kennedy Class I bilateral distal-extension edentulism. A secondary objective was to evaluate implant survival and peri-implant outcomes over a mean follow-up period of 34 months. Thirty-three partially edentulous adult participants (aged 36–87 years) were recruited. Included participants had sufficient bone height to accommodate 6 mm implants without the need for bone augmentation. A strict exclusion criteria included current smoking, uncontrolled diabetes, pregnancy or lactation, and use of immunosuppressive or antiresorptive medications. Random allocation to receive either CRPDs (n = 19) or IARPDs supported by two short implants (n = 14) was conducted after initial CRPD fabrication. Both implant- and non-implant-related biologic complications were recorded at baseline and annual follow-up visits up to four years. Parameters included caries, gingival inflammation, abutment tooth loss, peri-implant mucositis, peri-implantitis, and marginal bone level (MBL) changes. Statistical analyses were performed using chi-square tests, Fisher’s exact test and paired and unpaired t-tests, with significance set at p = 0.05. Non-implant biologic complications affected 44.7% of abutment teeth in the CRPD group and 21.4% in the IARPD group; however, this difference was not statistically significant (p > 0.05). The most common complications were gingival inflammation and caries. One abutment tooth was lost in the CRPD group versus none in the IARPD group. Peri-implant mucositis and peri-implantitis were observed in 42.9% and 10.7% of implants, respectively. Implant survival was 81.2%. Most MBL occurred prior to prosthetic loading, with minimal loss thereafter. Both CRPDs and IARPDs are viable treatment options for patients with Kennedy Class I edentulism, with no significant difference in the incidence of biologic complications between groups.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 2","pages":"83-84"},"PeriodicalIF":2.3,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12204855/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of alternative agents to Carnoy’s solution in the prevention of recurrence in odontogenic keratocyst: a systematic review and meta-analysis","authors":"Samyuktha Aarthi, Monal Yuwanati, Pratibha Ramani, Gheena Sukumaran","doi":"10.1038/s41432-025-01138-3","DOIUrl":"10.1038/s41432-025-01138-3","url":null,"abstract":"Odontogenic keratocyst (OKC) is aggressive cyst with high recurrence rates, traditionally treated using Carnoy’s solution (CS) as an adjunct to surgical enucleation. However, the toxicity and potential complications of CS, including neurotoxicity and tissue damage, necessitate the exploration of safer alternatives. The aim of systematic review was to evaluate potential alternatives to CS for preventing recurrence and minimizing postoperative complications in OKC. Studies were searched and retrieved from PubMed, Scopus, and Web of Science using relevant keywords. Inclusion criteria focused on studies evaluating alternatives to CS for OKC treatment, while reviews, case reports, and non-clinical studies were excluded. Quality assessment was performed using the Newcastle-Ottawa Scale and Cochrane Risk of Bias 2 Tool. Data extraction included study design, intervention, recurrence rates, and complications. Findings were summarized descriptively. Meta-analysis (random-effect model) was performed for recurrence in OKC. Six studies met the inclusion criteria after examining 280 studies. These studies examined recurrence and post-operative complications in CS, modified CS (MCS), and 5- Fluorouracil (5-FU) treated OKC cases. The recurrence events were 15/153 with CS and 37/200 with MCS; however, no recurrence was recorded for 5-FU. Paresthesia was seen in 17/74 of OKC-treated CS/MCS cases and 12/72 of OKC-treated 5-FU cases after surgery. The random-effects model estimated a pooled risk ratio of 0.13 (95% CI: 0.02 to 0.68, p = 0.015), suggesting that the 5-FU treated OKC patients was significantly less likely to experience recurrence than the CS/MCS treated OKC patients. 5-FU is found to be a better alternative to CS or MCS in terms of recurrence and postoperative complications in OKC. While 5-FU and/or CS remain effective, its side effects highlight the need for safer, equally effective alternatives. Future research should focus on long-term outcomes and the efficacy of novel treatments, including herbal therapies.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 3","pages":"151-151"},"PeriodicalIF":2.3,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143960722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anaesthesia for mandibular premolars with symptomatic irreversible pulpitis – which nerve block is best?","authors":"Ellis Hayes","doi":"10.1038/s41432-025-01142-7","DOIUrl":"10.1038/s41432-025-01142-7","url":null,"abstract":"Sülek T, Dumani A, Küden C, Kussever H, Yoldas O. Anaesthetic effectiveness of mental/incisive nerve block versus inferior alveolar nerve block in mandibular first and second premolars with symptomatic irreversible pulpitis: a randomised clinical trial. J Endod 2025; https://doi.org/10.1016/j.joen.2025.01.016 . This study is a randomised, double-blinded, parallel-group clinical trial investigating the efficacy of Mental Nerve Block (MNB) and Inferior Alveolar Nerve Block (IANB) techniques for anaesthesia of mandibular Premolars with Symptomatic Irreversible Pulpitis (SIP). The aim of the clinical trial is to establish if one anaesthetic technique is superior in facilitating Endodontic treatment in Mandibular Premolar Teeth with SIP and to explore if a difference is observed when comparing anaesthesia of First and Second Premolars with use of MNB and IANB techniques. Patients were enroled as per strict inclusion and exclusion criteria, then attended for Endodontic treatment of a Mandibular Premolar Tooth with SIP. Local anaesthetic block technique was determined by random assignment to MNB or IANB. To ensure blinding of the operator with regards to the anaesthesia method, one clinician administered anaesthesia and placed dental dam, and a second clinician completed the procedure. In total, 120 patients with a diagnosis of SIP of a Mandibular Premolar Tooth were enroled in the clinical trial. Inclusion criteria required participants be aged 18 to 65 years old and ASA Class I/II. Clinical signs indicative of SIP were required, including: carious pulpal exposure, haemorrhage during cavity preparation and prolonged pain in response to and persisting after thermal stimuli. Participants were excluded from the trial if they experienced pain involving multiple teeth or if there was use of pharmacological agents, with the ability to influence pain perception, within 6 hours of treatment. Participants were excluded from the trial if there was radiographic evidence of Periapical pathology, symptoms indicative of Apical Periodontitis or lack of anaesthesia 15 minutes after IANB administration. The sample size was determined using G*Power software and 60 patients were allocated to each group: MNB and IANB respectively. The drug preparation administered in all cases was 1.8 ml Articaine 4% with 1:100,000 epinephrine hydrochloride and the aspirating technique was used. Statistical analysis was completed using SPSS Statistics. Patients were verbally questioned prior to Endodontic treatment, with responses recorded on the Numerical Rating Scale (NRS). Pain scores were recorded relating to pre-operative assessments, cold tests, cavity preparation and pulp extirpation. Success rates for the MNB and IANB anaesthesia groups were explored using chi-squared and probability ratio tests. The Man-Whitney U test allowed for comparison of tooth type and gender. In this study, success was defined as patients completing treatment with no pain (NRS = 0) or mild pain (NRS < 3","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 2","pages":"87-88"},"PeriodicalIF":2.3,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bone grafting in socket shield: necessary or optional for immediate implants?","authors":"Carlos Fernando Mourão","doi":"10.1038/s41432-025-01139-2","DOIUrl":"10.1038/s41432-025-01139-2","url":null,"abstract":"Gurbuz E, Ceylan E Comparison of a non-grafted socket shield technique with guided bone regeneration in immediate implant placement: a randomized clinical trial. Int J Oral Maxillofac Surg 2025; 54: 356–364. This randomised clinical trial compared the outcomes of a non-grafted socket shield technique (SST) versus guided bone regeneration (GBR) in immediate dental implant placement within the maxillary aesthetic zone, evaluating clinical, aesthetic, and radiographic outcomes over a 1-year period. Participants were adults with a single unrestorable tooth in the maxillary anterior region requiring extraction and immediate implant placement. A total of 24 patients completed the study, with 12 allocated to each group (SST and GBR), following exclusions due to complications such as shield mobility or incomplete follow-up. Clinical parameters (peri-implant pocket depth, plaque and bleeding indices, keratinized mucosa width, and mucosal thickness) and radiographic measures (horizontal and vertical bone levels) were assessed at baseline and 1-year post-procedure. Aesthetic outcomes were evaluated using the pink aesthetic score (PES). Statistical comparisons employed t tests and Mann–Whitney U-tests, with significance set at P < 0.05. At 1 year, no notable differences emerged between SST and GBR groups in terms of peri-implant health (pocket depth, plaque, bleeding) or bone stability (horizontal and vertical bone levels). However, the SST group exhibited significantly wider keratinized mucosa (P = 0.013) and superior aesthetic outcomes, with higher PES scores (P = 0.004), compared to the GBR group. Both SST and GBR proved effective in maintaining hard tissue integrity during immediate implant placement in the aesthetic zone. The SST, however, offered advantages in soft tissue preservation and aesthetic enhancement, suggesting it as a viable alternative to GBR for single-tooth replacements in this region.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 2","pages":"78-79"},"PeriodicalIF":2.3,"publicationDate":"2025-04-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analyzing the influence of scanning speeds and distances on digital intraoral scans: a systematic review and meta-analysis","authors":"Ravinder S. Saini, Syed Altafuddin Quadri, Masroor Ahmed Kanji, Rayan Ibrahim H Binduhayyim, Anna Avetisyan, Seyed Ali Mosaddad, Artak Heboyan","doi":"10.1038/s41432-025-01135-6","DOIUrl":"10.1038/s41432-025-01135-6","url":null,"abstract":"This study aimed to evaluate the influence of scanning speed and distance on the precision and quality of digital intraoral scans. The PICO strategy was employed to delineate the inclusion and exclusion criteria. The acquired records underwent filtration according to eligibility criteria, with essential information subsequently extracted. The meta-analysis, facilitated by Review Manager 5.4, utilized chi-square and the inconsistency index, along with forest plots. The standardized mean difference (SMD) was employed for the comparative analysis of study groups. Additionally, the study encompassed assessments of publication bias and the quality of included studies. The search was conducted using three Internet databases: PubMed, ScienceDirect, and the Cochrane Library. Among the evaluated scanners (Trios 3, Trios 4, iTero, Primescan, Medit i500), only TRIOS 3 exhibited a statistically significant sensitivity to scanning parameters (SMD = −4.03; 95% CI: −7.26 to −0.80; P = 0.01). Increased scanning distances and faster speeds markedly reduced its accuracy, likely due to its older optical technology lacking real-time error correction features present in newer models like TRIOS 4 and Primescan. No significant effects were observed for TRIOS 4, Primescan, or Medit i500 (P > 0.05), suggesting their advanced hardware/software mitigates parameter variability. Clinicians using TRIOS 3 should prioritize shorter scanning distances (5–10 mm) and slower speeds to optimize accuracy, as its performance is highly dependent on operator-controlled parameters. In contrast, newer scanners (e.g., TRIOS 4, Primescan) demonstrate greater resilience to distance/speed variations, enabling flexible clinical workflows. These findings underscore the importance of device-specific protocols to enhance digital impression reliability in restorative and prosthetic dentistry.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 3","pages":"148-148"},"PeriodicalIF":2.3,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143980817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep convolutional neural networks for early detection of interproximal caries using bitewing radiographs: A systematic review","authors":"Soundar Ida Mahizha, Joseph Annrose, Jeyebalaji Mano Christaine Angelo, Israel Domilin Shyni, G. valanthan veda Giri","doi":"10.1038/s41432-025-01134-7","DOIUrl":"10.1038/s41432-025-01134-7","url":null,"abstract":"To thoroughly review Deep Convolutional Neural Networks for detecting interproximal caries with bitewing radiographs. Data was collected from studies that utilized Deep Convolutional Neural Networks (DCNN) focused on the analysis of bitewing radiographs taken with intraoral X-ray units. A comprehensive literature search was conducted across various scholarly databases including Google Scholar, MDPI, PubMed, ResearchGate, ScienceDirect, and IEEE Xplore, encompassing 2014 to 2024. The risk of bias assessment utilized the current version of the Quality Assessment Tool for Diagnostic Accuracy Studies (QUADAS-2). After reviewing 291 articles, 10 studies met the criteria and were analyzed. All 10 studies used bitewing radiographs, focusing on deep learning tasks such as segmentation, classification, and detection. The sample sizes varied widely from 112 to 3,989 participants. Convolutional neural networks (CNNs) were the most commonly used model. According to the QUADAS-2 assessment, only 40% of the studies included in this review were found to have a low risk of bias in the reference standard domain. A Deep Convolutional Neural Networks based caries detection system helps in the early identification of caries by analyzing bitewing radiographs and reduces diagnostic errors. By identifying early-stage lesions, patients can undergo minimally invasive treatments instead of more complex procedures, thereby improving patient outcomes in dental care. This systematic review provides an overview of various studies that utilize deep learning models to identify interproximal caries lesions in bitewing radiographs. It highlights the efficacy of YOLOv8 in detecting interproximal caries from bitewing radiographs compared to other Deep CNN models.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 2","pages":"117-117"},"PeriodicalIF":2.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can caries in anterior teeth of toddlers predict severe caries in posterior teeth?","authors":"Meenakshi Lall","doi":"10.1038/s41432-025-01128-5","DOIUrl":"10.1038/s41432-025-01128-5","url":null,"abstract":"Tavares B S, Bendo C B, Fernandes I B, Coelho V S, Ramos-Jorge M L, Ramos-Jorge J Dental caries in anterior teeth of babies can predict the occurrence of severe dental caries in posterior teeth: a 3-year cohort study. Eur Arch Paediatr Dent 2024; https://doi.org/10.1007/s40368-024-00968-6 . A three-year study of 1–2 years old toddlers to check if the dental caries of primary anterior teeth is a precursor to them developing severe caries on their primary molars. A cohort of 99 children, between the ages of 1–2 years old, reviewed for dental caries. This study looked at the toddlers at the baseline and then reviewed them after three years. Primary independent variable in this study was carious anterior tooth. Consideration given to independent variables like economic status, primary carers’ education, oral hygiene (including nighttime routine), history of tooth ache, and sucrose intake. Differences between the presence and absence of severe dental caries in posterior teeth according to independent variables were evaluated using the chi-square test. Unadjusted and adjusted relative risks for the association between independent variables and the incidence of severe caries in posterior teeth were estimated using Poisson regression models with robust variance. There is threefold increased risk of developing severe dental caries in posterior teeth for the children who had caries in anterior teeth at the baseline (RR 3.33; 95% CI 2.06–5.37). This high-risk group belonged to low-income families (RR 2.75; 95% CI 1.40–5.39), who did not perform nighttime oral hygiene (RR 1.76; 95% CI 1.10–2.80), and had a higher frequency of sucrose intake (RR 4.07; 95% CI 2.03–8.19), at the baseline and at follow-up. The presence of dental caries in the primary anterior teeth of 1 to 2-year-old toddlers can have a higher incidence of severe caries in posterior teeth. Other factors e.g. low economic status, absence of nighttime oral hygiene, high sucrose intake both at baseline and follow-up were considerable risk factors for the presence of severe dental caries in the primary posterior teeth.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 1","pages":"40-41"},"PeriodicalIF":0.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Grading the strength and certainty of the scientific evidence of the bidirectional association between periodontitis and noncommunicable diseases: an umbrella review","authors":"Carolina Rodríguez-Medina, Sandra Amaya Sánchez, Adolfo Contreras, Javier Enrique Botero","doi":"10.1038/s41432-025-01132-9","DOIUrl":"10.1038/s41432-025-01132-9","url":null,"abstract":"Periodontitis and various noncommunicable diseases (NCDs) have been proposed to have a bidirectional relationship. The purpose of this umbrella review is (1) to synthesize the evidence and (2) to grade the strength and certainty of the scientific evidence regarding the bidirectional association between periodontitis and NCDs. Electronic databases were systematically searched from January 2021 and July 2024; MEDLINE (via PubMed), Embase and SciELO. Potential epidemiologic systematic reviews with meta-analysis that studied the bidirectional association between periodontitis and NCDs were identified by two independent reviewers and filtered by title and abstract according to the selection criteria. The strength and the quality and certainty of the evidence was assessed according to the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) guide. 561,554 potential results were identified. After removing duplicates and excluding records deemed ineligible by automated filters, 450 results were screened by title and abstract. This process led to 41 records being appraised in full-text. Of these, 17 were further excluded leaving a total of 24 systematic reviews that met the inclusion criteria. 24 systematic reviews with a total of 32 NCDs were appraised and consolidated. Risk of bias assessment indicated that 21 systematic reviews (87.5%) demonstrated low bias (high quality), 2 had medium bias, and 1 exhibited high bias (low quality). Key issues identified included the formulation of explicit research questions, critical appraisal, data extraction, and publication bias. The association between periodontitis and NCDs was strong in 1 systematic review, moderate in 8, weak in 10 and absent in 7 systematic reviews. The strength of the association between NCDs and periodontitis was moderate in 6 systematic reviews and weak in 3 systematic reviews. The size of the reported effect (odds ratio/risk ratio/hazard ratio) was broader with increasing strength. Although data supports the association between periodontitis and some NCDs, and to a lesser extent between some NCDs and periodontitis, the certainty of the evidence was classified as low to very low. There is some data that, with varying degrees of association and low to very low certainty, provide evidence that periodontitis may be a potential risk factor for some NCDs and vice versa.","PeriodicalId":12234,"journal":{"name":"Evidence-based dentistry","volume":"26 3","pages":"147-147"},"PeriodicalIF":2.3,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.comhttps://www.nature.com/articles/s41432-025-01132-9.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}