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Determination of Additives in Cigarettes Utilizing Evolved Gas Analysis (EGA) 利用逸出气体分析(EGA)测定香烟中的添加剂
Pub Date : 2016-01-01 DOI: 10.5923/J.FPH.20160602.01
Karissa Ferguson, M. Samide, C. Schmicker, T. Schenk, Anne M. Wilson
While additives to consumer products must be listed in order by amount, it is not required to report the actual amounts of these additives. Given that impacts on human health are dose dependent, knowledge of additive amounts would aid discussions of the safety of these compounds for inhalation. Additives for cigarettes include flavors, such as menthol, and propylene glycol, a humectant. Rapid determination of the amounts of menthol and propylene glycol additives in cigarettes was accomplished utilizing evolved gas analysis (EGA) - gas chromatography (GC) - flame ionization detection (FID). Careful preparation of samples and appropriate sample storage are critical components to this study. Menthol amounts in cigarettes were consistent with previous studies and this represents the first report of propylene glycol amounts.
虽然消费品中的添加剂必须按数量顺序列出,但不需要报告这些添加剂的实际含量。鉴于对人体健康的影响是剂量依赖性的,了解添加剂的数量将有助于讨论这些化合物吸入的安全性。香烟的添加剂包括香料,如薄荷醇和丙二醇,一种保湿剂。采用逸出气体分析(EGA) -气相色谱(GC) -火焰电离检测(FID)技术,实现了香烟中薄荷醇和丙二醇添加剂的快速测定。仔细制备样品和适当的样品储存是本研究的关键组成部分。香烟中薄荷醇的含量与之前的研究一致,这是丙二醇含量的首次报告。
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引用次数: 1
Food Insecurity, Not Stress is Associated with Three Measures of Obesity in Low-Income, Mexican-American Women in South Texas. 南得克萨斯州低收入墨西哥裔美国妇女肥胖症的三个衡量指标与食物不安全而非压力有关。
Pub Date : 2016-01-01
Jennifer J Salinas, William Shropshire, Ana Nino, Deborah Parra-Medina

Objective: To determine the relationship between obesity, food insecurity and perceived stress in very low income Mexican American women.

Design: Cross-sectional baseline data analysis of a randomized clinical trial.

Setting: Texas-Mexico border region of South Texas.

Subjects: Very Low Income Mexican American Women.

Results: The relationship between obesity and food insecurity in a sample of very low income Hispanic women living in South Texas depends on the measure of obesity and the dimension of food insecurity. The only measure of food insecurity associated with all measures of obesity was often not having enough money to afford to eat balanced meals. Waist circumference was associated with the most dimensions of food insecurity, while BMI had the least associations. Finally, perceived stress was not significantly associated with BMI, waist circumference or percent body fat when adjusted for other covariates.

Conclusions: We have found a strong and significant relationship between food insecurity related to having enough resources to eat a balanced diet and BMI, waist circumference, and percent body fat in low-income Mexican American women. While behavioural change is an important strategy for reducing obesity, consideration may need to be made as to how food access with high nutritional value, may be in and of itself a contributing factor in obesity in low income populations.

目的确定收入极低的墨西哥裔美国妇女的肥胖、食物不安全和感知压力之间的关系:设计:随机临床试验的横断面基线数据分析:环境:得克萨斯州与墨西哥交界的得克萨斯州南部地区:结果:肥胖与食物过量之间的关系是什么?结果:生活在南得克萨斯州的极低收入拉美裔妇女样本中,肥胖与粮食不安全之间的关系取决于肥胖的衡量标准和粮食不安全的维度。唯一与所有肥胖指标相关的食物不安全指标是经常没有足够的钱来负担均衡膳食。腰围与食物不安全的关联度最高,而体重指数的关联度最低。最后,在对其他协变量进行调整后,感知到的压力与体重指数、腰围或体脂率没有明显关联:我们发现,在低收入的墨西哥裔美国妇女中,与是否有足够资源摄入均衡饮食相关的食物不安全与体重指数、腰围和体脂百分比之间存在着强烈而显著的关系。虽然行为改变是减少肥胖的重要策略,但可能需要考虑的是,获得高营养价值的食物本身可能是导致低收入人群肥胖的一个因素。
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引用次数: 0
Trends for the Application of Passion Fruit Industrial By-Products: A Review on the Chemical Composition and Extraction Techniques of Phytochemicals 百香果工业副产物的应用趋势——植物化学成分及提取技术综述
Pub Date : 2015-10-01 DOI: 10.5923/J.FPH.20150505.03
J. Viganó, Julian Martínez
This work presents a review on the composition and extraction techniques for recovering phytochemicals from passion fruit by-products. The review approaches on the characteristics of each phytochemical and its benefits to human health. It was observed that the by-products of passion fruit contain a range of interesting substances, and for their recovery the application of environmentally friendly extraction techniques, such as supercritical fluid extraction (SFE) and pressurized liquid extraction (PLE), are suggested as single or sequential procedures. The future perspectives of this review encourage the application of these techniques to a complete recovery of passion fruit by-products.
本文综述了从百香果副产品中提取植物化学物质的成分和提取技术。综述了各种植物化学物质的特点及其对人体健康的益处。研究发现,百香果副产物中含有多种有益物质,建议采用超临界流体萃取(SFE)和加压液体萃取(PLE)等环境友好型提取技术,对其进行单次或连续提取。展望未来,这篇综述鼓励这些技术应用于百香果副产品的完全回收。
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引用次数: 22
Relationship between Common Dietary Polyphenols and Obesity-Induced Inflammation 常见膳食多酚与肥胖诱导炎症的关系
Pub Date : 2015-06-01 DOI: 10.5923/J.FPH.20150503.04
Lada Tucakovic, N. Colson, I. Singh
The incidence of obesity and its related metabolic disorders has escalated dramatically in the past decades worldwide. Defined as abnormal or excessive fat accumulation caused by an imbalance between energy intake and expenditure, obesity is presently the major health challenge in developed countries and the causative factor of numerous diseases such as heart problems, hypertension, hyperlipidemia and type 2 diabetes. Presence of high level of cytokines and acute phase proteins associated with inflammation in obese individuals relates obesity to chronic low-grade inflammation. Obesity-induced inflammation has an impact on insulin resistance and cardiac health. Polyphenols including catechins, tocopherols, resveratrol, curcumin and anthocyanins have been shown to reduce adipose tissue inflammation. It has been broadly accepted that adipocyte dysfunction plays a major role in development of obesity and obesity related complications. This state is characterised by hypersecretion of pro-atherogenic, pro-inflammatory and pro-diabetic adipokines as well as decreased secretion of adiponectin. The dietary polyphenols described in this review have potential as nutritional strategies for the prevention of obesity and associated inflammation as well as increase in insulin sensitivity in diabetic people.
在过去的几十年里,世界范围内肥胖及其相关代谢紊乱的发病率急剧上升。肥胖被定义为由于能量摄入和消耗之间的不平衡而导致的异常或过度的脂肪积累,是目前发达国家面临的主要健康挑战,也是心脏病、高血压、高脂血症和2型糖尿病等许多疾病的致病因素。肥胖个体中与炎症相关的高水平细胞因子和急性期蛋白的存在将肥胖与慢性低度炎症联系起来。肥胖引起的炎症对胰岛素抵抗和心脏健康有影响。包括儿茶素、生育酚、白藜芦醇、姜黄素和花青素在内的多酚已被证明可以减少脂肪组织的炎症。脂肪细胞功能障碍在肥胖及肥胖相关并发症的发生中起着重要作用,这一观点已被广泛接受。这种状态的特征是促动脉粥样硬化、促炎症和促糖尿病的脂肪因子的高分泌,以及脂联素的分泌减少。本综述中描述的膳食多酚有可能作为预防糖尿病患者肥胖和相关炎症以及胰岛素敏感性增加的营养策略。
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引用次数: 10
Thin Layer Chromatographic Analysis of Annatto Extracts Obtained Using Supercritical Fluid 超临界流体制备红木提取物的薄层色谱分析
Pub Date : 2015-01-01 DOI: 10.5923/j.fph.20150504.05
C. L. Albuquerque, Á. L. Santana, M. Angela, A. Meireles
The goal of this paper was to qualitatively identify the chemical composition of annatto extracts obtained by supercritical fluid extraction (SFE) using thin layer chromatography (TLC) in terms of volatile oil compounds, compounds with antioxidant activity and phenolic compounds. The mobile phase that achieved the best separation of the studied compounds of interest presented in the extracts was used. The γ-tocotrienol and δ- tocotrienol antioxidants as well as squalene and β-sitosterol were identified by comparison of their Rf values to the same constituents present in the 30% Tocomin commercial sample. The chemical profile of extracts varied as a function of extraction time. The intensity of antioxidants, phenolic compounds and volatile oil compounds was reduced, while the intensity of carotenes (bixin) was increased.
以超临界流体萃取法提取的红木提取物为研究对象,采用薄层色谱法对其挥发油类化合物、抗氧化类化合物和酚类化合物进行定性鉴定。采用流动相对提取物中所研究的感兴趣的化合物进行最佳分离。γ-生育三烯醇和δ-生育三烯醇抗氧化剂以及角鲨烯和β-谷甾醇通过与30% Tocomin商业样品中相同成分的Rf值进行比较鉴定。萃取物的化学成分随萃取时间的变化而变化。抗氧化剂、酚类化合物和挥发油类化合物的强度降低,而胡萝卜素(bixin)的强度增加。
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引用次数: 9
Supercritical Water Gasification of Biomass for Hydrogen Production: Variable of the Process 生物质超临界水气化制氢:过程变量
Pub Date : 2015-01-01 DOI: 10.5923/j.fph.20150503.05
D. Lachos‐Perez, J. M. Prado, P. C. Torres-Mayanga, T. Forster‐Carneiro, M. Meireles
Waste biomass has various origins, such as agricultural crops, food waste, animal waste, municipal solid waste, and has the potential to be converted into energy and applied in biorefineries, thus contributing with lignocellulosic material. The emerging technology "Supercritical Water Gasification" has a great potential for recycling biomass for the production of synthesis gas with a higher percentage of hydrogen. The supercritical water gasification (SCWG) does not require drying; thus, the problem of drying is largely avoided by the SCWG and can be used for biomass with high percentage of humidity. The conversion efficiency of the SCWG is generally higher when compared with conventional technologies. This paper reviews known and emerging key supercritical water properties that influence the SCWG of biomass (viscosity, density, dielectric constant and ionic product), the advantages of the SCWG with respect to conventional gasification, the economic viability of the process, and the kinetics of the biomass in the process, this review describes the factors that influence the process (temperature, pressure, residence time, concentration, effect of the catalyst, effect of the reactor geometry, reactor design, heating rate of the biomass particle and type of biomass). Finally, this article concludes that the technology "supercritical water gasification" has great potential for a cleaner biogas production, with a high percentage of hydrogen, by different types of biomass, thus reducing the pollution and CO2 emissions.
废弃生物质来源多种多样,如农作物、食物废物、动物废物、城市固体废物,并有可能转化为能源并应用于生物炼制,从而提供木质纤维素材料。新兴技术“超临界水气化”在回收生物质生产含氢比例更高的合成气方面具有巨大潜力。超临界水气化(SCWG)无需干燥;因此,干燥问题在很大程度上被SCWG避免了,并且可以用于具有高湿度百分比的生物质。与传统技术相比,超临界水轮机的转换效率普遍较高。本文综述了已知的和新兴的影响生物质超临界水的关键性质(粘度、密度、介电常数和离子产物),超临界水相对于传统气化的优势,该过程的经济可行性,以及过程中生物质的动力学,这篇综述描述了影响该过程的因素(温度、压力、停留时间、浓度、催化剂的作用、反应器几何形状的影响,反应器设计,生物质颗粒加热速率和生物质类型)。最后,本文得出结论,“超临界水气化”技术具有巨大的潜力,可以通过不同类型的生物质生产更清洁的沼气,氢气含量更高,从而减少污染和二氧化碳排放。
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引用次数: 17
Novel extraction method to produce active solutions from plant materials. 从植物原料中提取活性溶液的新方法。
Pub Date : 2015-01-01 DOI: 10.5923/j.fph.20150502.02
R. A. C. Torres, D. Santos, M. Meireles
A novel selective extraction method to produce active solutions with from plant materials was developed. Named by our research group as High Turbulence Extraction Assisted by Ultrasound (HTEAU) the feasibility of this process was demonstrated using semi-defatted annatto seeds (Bixa orellana L.) as a model plant material and ethanol as extracting solvent. HTEAU process combines the use of two types of commercial equipments and technologies. The first is Ultra-turrax ® rotor-stator technology, which produces high turbulence in the plant material bed by high extracting solvent circulation flow rate (until 2000 cm 3 /min) and the second is ultrasound technology, which is recognized to improve the extraction rate by the increasing the mass transfer and possible rupture of cell wall due the formation of microcavities. These equipments were coupled and put into operation at its maximum power of operability and the values for these parameters were determined through simultaneous optimization of oils, phenols, bixin recoveries. The effects of extraction method and solvent mass to feed mass ratio (S/F) on oils, phenols, bixin recoveries were evaluated by analyses of variance (ANOVA), demonstrating that the coupling of ultrasound probe into the Ultra-turrax ® equipment statistically promotes the selective extraction of total phenols and bixin.
提出了一种以植物原料为原料制备活性溶液的新方法。本课题组以半脱脂红木种子(Bixa orellana L.)为模式植物材料,以乙醇为提取溶剂,验证了该工艺的可行性,并将其命名为超声辅助高湍流提取(HTEAU)。HTEAU工艺结合了两种商用设备和技术的使用。第一种是Ultra-turrax®转子-定子技术,它通过高提取溶剂循环流速(直到2000 cm 3 /min)在植物材料床中产生高湍流;第二种是超声波技术,它被认为通过增加传质和微腔形成导致细胞壁破裂来提高提取率。通过对油、酚类、比新收率的同时优化,确定了这些参数的取值。通过方差分析(ANOVA)评价了提取方法和溶剂质量与进料质量比(S/F)对油脂、酚类和碧心回收率的影响,结果表明超声探针与Ultra-turrax®设备的耦合在统计学上促进了总酚类和碧心的选择性提取。
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引用次数: 9
Study of an Extraction Process as the Pretreatment Step for Sugar Production from Acid Hydrolysis 酸水解制糖的提取预处理工艺研究
Pub Date : 2015-01-01 DOI: 10.5923/j.fph.20150502.03
Sylvia Alcázar-Alay, Fiorella P. Cárdenas-Toro, D. Santos, M. Meireles
This work involves the residues of three plant species used in industry: Brazilian ginseng (Pfaffia glomerata), palm (Elaeis guineensis) and annatto (Bixa orellana L.). The studied plant residues come from oil and biocompounds extraction: Soxhlet extraction (SE), Pressurized liquid extraction (PLE) and Supercritical fluid extraction (SFE). The effects of these extraction processes on the structures of plant matrices were observed using scanning electron microscopy (SEM). Plant residues were subjected to acid hydrolysis. The hydrolysis process was conducted using a 0.5 L reactor at atmospheric pressure and the solvent at boiling temperature. Brazilian ginseng was hydrolyzed in hydrochloric acid solution (0.5, 2.5 and 5.0%, v/v) for 60 min. Palm pressed fiber and annatto were hydrolyzed in sulfuric acid solution (1.5 and 3.0%, v/v) for 90 min. Sugars produced by the hydrolysis were quantified and interpreted as Reducing sugars (RS) (g glucose/100 g raw material) and Total reducing sugars (TRS) (g sucrose/100 g raw material) by a spectrophotometric method. The results observed by SEM showed that the extraction treatments modified the vegetable matrix with respect to its structure and component ratio. The acid hydrolysis process of each vegetable matrix showed different reaction kinetics. The availability and source of the sugar polymers and the acid concentration were variables that affected the hydrolysis reaction.
这项工作涉及工业上使用的三种植物的残留物:巴西人参(Pfaffia glomerata),棕榈(Elaeis guineensis)和红木(Bixa orellana L.)。研究的植物残油提取方法包括索氏萃取法(SE)、加压液体萃取法(PLE)和超临界流体萃取法(SFE)。利用扫描电镜(SEM)观察了这些提取过程对植物基质结构的影响。植物残体被酸水解。采用0.5 L常压反应器和沸点溶剂进行水解。巴西人参在盐酸溶液(0.5、2.5和5.0%,v/v)中水解60 min。棕榈压榨纤维和红木在硫酸溶液(1.5和3.0%,v/v)中水解90 min。水解产生的糖通过分光光度法定量解释为还原糖(RS) (g葡萄糖/100 g原料)和总还原糖(TRS) (g蔗糖/100 g原料)。扫描电镜观察结果表明,提取处理改变了蔬菜基质的结构和成分比例。每种蔬菜基质的酸水解过程表现出不同的反应动力学。糖聚合物的可得性、来源和酸浓度是影响水解反应的变量。
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引用次数: 13
Effect of the Flavonol Quercetin on Human Platelet Function: A Review 黄酮醇槲皮素对人血小板功能影响的研究进展
Pub Date : 2015-01-01 DOI: 10.5923/J.FPH.20150501.01
S. Mosawy
Quercetin (Que) is one of the most abundant and potent naturally occurring antioxidant. Que has been shown to exert many biological activities, including antiplatelet activity. Indeed, Que was shown to inhibit platelet aggregation in response to platelet agonists, such as ADP, collagen, thrombin and arachidonic acid. However, the lowest Que concentration that significantly inhibits agonist-induced platelet aggregation remains contradictory. In addition, to anti-aggregatory effects, Que was demonstrated to inhibit platelet dense and alpha granule exocytosis when stimulated by different platelet agonists. Que was also shown to inhibit multiple platelet protein kinases, including, PI3K, Akt, PLC and PKC. The main aim of this review focuses on the inhibitory effects of Que on human platelet function.
槲皮素(Que)是最丰富和最有效的天然抗氧化剂之一。Que已被证明具有许多生物活性,包括抗血小板活性。事实上,Que对血小板激动剂(如ADP、胶原蛋白、凝血酶和花生四烯酸)有抑制血小板聚集的作用。然而,能显著抑制激动剂诱导的血小板聚集的最低Que浓度仍然是矛盾的。此外,在抗聚集作用方面,Que在不同的血小板激动剂刺激下可抑制血小板致密和α颗粒胞吐。Que还可抑制多种血小板蛋白激酶,包括PI3K、Akt、PLC和PKC。本文主要就其对人血小板功能的抑制作用进行综述。
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引用次数: 8
Obtaining oligo- and monosaccharides from agroindustrial and agricultural residues using hydrothermal treatments. 利用水热法从农业、工业和农业残留物中提取寡糖和单糖。
Pub Date : 2014-01-01 DOI: 10.5923/j.fph.20140403.08
Fiorella P. Cárdenas-Toro, Sylvia Alcázar-Alay, T. Forster‐Carneiro, M. Meireles
Agricultural and agroindustrial residues are major sources of cellulose, hemicellulose, and starch that can be converted into bioactive compounds, such as oligosaccharides and monosaccharides, using various chemical and biological methods. These bioactive compounds can be used as raw materials by food, cosmetic and pharmaceutical industries, as well as in the production of intermediate products and the development of biomaterials by chemical industries. In Brazil, the major industrial residues, which are corn residues, soybean residues, sugarcane bagasse, palm and coconut fibers, and grape and tomato seeds, among others, are produced at a rate of approximately of 600 million tons per year. Thus, the utilization of these residues using sustainable technology is of great interest. Hydrothermal treatment is a green technology that includes autohydrolysis as well as subcritical and supercritical hydrolysis, in which water is used at high pressures and temperatures to recover polysaccharides from complex vegetal matrices. The hydrolytic mechanisms can be improved by changing the ionic product or the polarity and electrical conductivity of water in subcritical and supercritical states. These properties promote the selective dissolution of the starch, hemicellulose and cellulose in the residues. The conversion of starch and hemicellulose into oligosaccharides and monosaccharides is preferentially performed at temperatures of less than 200°C. In contrast, the conversion of cellulose into oligosaccharides is promoted at temperatures greater than 200°C, with the highest amount oligosaccharide formation occurring at close to the critical point. In this article, the main biomass components, the properties of water under subcritical and supercritical conditions, and the latest studies of polysaccharide conversion in biomasses using hydrothermal treatments are reviewed.
农业和农业工业残留物是纤维素、半纤维素和淀粉的主要来源,它们可以通过各种化学和生物方法转化为生物活性化合物,如低聚糖和单糖。这些生物活性化合物可以用作食品、化妆品和制药工业的原料,也可以用于化学工业生产中间产品和开发生物材料。在巴西,主要的工业残留物,包括玉米残留物、大豆残留物、甘蔗渣、棕榈和椰子纤维、葡萄和番茄种子等,以每年约6亿吨的速度生产。因此,利用可持续技术利用这些残留物是非常有趣的。水热处理是一种绿色技术,包括自水解、亚临界和超临界水解,其中水在高压和高温下从复杂的植物基质中回收多糖。通过改变亚临界和超临界状态下的离子产物或水的极性和电导率,可以改善水解机理。这些特性促进了淀粉、半纤维素和纤维素在残渣中的选择性溶解。淀粉和半纤维素转化成寡糖和单糖的最佳温度低于200℃。相比之下,纤维素向低聚糖的转化在高于200℃的温度下得到促进,在接近临界点时形成的低聚糖数量最多。本文综述了生物质的主要成分、亚临界和超临界条件下水的性质以及水热法转化生物质多糖的最新研究进展。
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引用次数: 34
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