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Pub Date : 2023-01-04 DOI: 10.26452/fjphs.v3i1.342
Neelofar H, Chekurthi Swetha Reddy, Kishore Bandarapalle, Karna Hari Priya, Koka Madhavi, Kanugonda Jaswanth Reddy
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引用次数: 0
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Pub Date : 2023-01-04 DOI: 10.26452/fjphs.v3i1.336
Venkata Narayana D
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Pub Date : 2023-01-04 DOI: 10.26452/fjphs.v3i1.340
Ayesha T, Kishore Bandarapalle, Rajasekhar K K, Tholla Bhagyamma, Mohit Ragavendra M R, Pathakota Bhuvan Kumar Reddy, Sindhu P
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Pub Date : 2023-01-04 DOI: 10.26452/fjphs.v3i1.337
Ankit Singh, Shailendra Bhatt
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Pub Date : 2023-01-04 DOI: 10.26452/fjphs.v3i1.351
K. Arun
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Pub Date : 2023-01-04 DOI: 10.26452/fjphs.v3i1.341
Neelam Injeti
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引用次数: 0
Effectiveness of Oral Hypoglycaemics in Type-2 Diabetes Mellitus Patients at a Tertiary Care Hospital : A Comparative Observational Study 三级医院口服降糖药对2型糖尿病患者的疗效:一项比较观察研究
Pub Date : 2022-12-10 DOI: 10.26452/fjphs.v2i4.330
K. Arun
Hyperglycemia, or a state of high blood sugar, is a symptom of diabetes mellitus (D.M.), a complicated chronic disease brought on by deficits in insulin production, activity, or both. Since type 2 diabetes mellitus is a frequent and spreading condition, it is a significant global public health issue. The International Diabetes Federation estimates that 629 million people will have diabetes by 2045, up from the current 425 million cases. The main objective is to compare the effectiveness of oral hypoglycaemics in Type-2 Diabetes Mellitus patients at a tertiary care hospital. This prospective observational study was carry out for six months at HKES’s Basaveshwar Teaching and General Hospital, Kalaburagi. Patients were enrolled based on eligibility criteria. Study populations of 120 subjects with incident Type 2 Diabetes Mellitus were enrolled. Among 120 issues, 25 (20.83%), 15 (12.5%), and 20 (16.66%) subjects are under the treatment of Biguanides, Sulfonylureas, and DPP-4 Inhibitors. 10 (8.33%), 30 (25%) and 20 (16.66%) subjects are under the treatment of Biguanides and Sulfonylureas combination, Biguanides and DPP-4 Inhibitors combination and Biguanides, Sulfonylureas and DPP-4 Inhibitors combination. Finally, conclude that the DPP4  Inhibitor combination group of drugs  is better than other anti-diabetic medications in maintaining good glycemic status in type 2 D.M. patients, particularly Biguanides+DPP-4 Inhibitors and then followed by Biguanides+DPP-4 Inhibitors + Sulfonylureas by comparing all the laboratory values obtained.
高血糖症,或高血糖状态,是糖尿病的一种症状,糖尿病是一种复杂的慢性疾病,由胰岛素分泌、活性不足或两者兼而有之引起。由于2型糖尿病是一种常见病和弥漫性疾病,它是一个重大的全球公共卫生问题。国际糖尿病联合会(International Diabetes Federation)估计,到2045年,全球将有6.29亿人患有糖尿病,高于目前的4.25亿人。主要目的是比较三级医院口服降糖药治疗2型糖尿病患者的疗效。这项前瞻性观察研究在卡拉布拉吉的香港大学Basaveshwar教学总医院进行了为期6个月的研究。患者根据入选标准入组。120例2型糖尿病患者被纳入研究人群。120例患者中,双胍类药物、磺脲类药物和DPP-4抑制剂分别为25例(20.83%)、15例(12.5%)和20例(16.66%),双胍类药物和磺脲类药物联用、双胍类药物和DPP-4抑制剂联用和双胍类药物、磺脲类药物和DPP-4抑制剂联用分别为10例(8.33%)、30例(25%)和20例(16.66%)。最后,通过对各项实验室数据的比较,得出DPP4抑制剂联合用药组在维持2型糖尿病患者良好血糖状态方面优于其他降糖药物,以双胍类药物+DPP-4抑制剂效果最好,其次为双胍类药物+DPP-4抑制剂+磺脲类药物。
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引用次数: 0
Case Study of Acute Liver Failure Due to Large B­-Cell Lymphoma 大B细胞淋巴瘤致急性肝衰竭病例分析
Pub Date : 2022-03-17 DOI: 10.26452/fjphs.v2i2.225
Gnana Prakash
This case study is about a 72 yrs elderly woman as for acute liver failed due to huge b-cell lymphoma diffusion. The patient was diagnosed with the disease in the past and was on treatment for it. However, she started showing symptoms of fatigue and jaundice which led to hospitalization. The study looks at her medical history and current condition as well as how her disease has progressed over time. It also discusses the various treatments that have been tried so far and their effects on her. A CT scan indicated a huge B-cell lymphoma diffusely involving the liver. The patient underwent an emergency laparotomy and resection of the liver lesion because her condition was deteriorating rapidly. The woman had an enlarged liver (10 cm) with a nodular surface and diffusely increased attenuation on CT scan. She also had a gallbladder wall thickening on ultrasound examination. She has been hospitalized for the further assessment as well as organization of her acute liver fail due to huge B-cell lymphoma dispersion. The seventy two yrs elderly women acute liver problem due to huge B-cell lymphoma dispersion has been hospitalized for such a liver transplant. The patient has been given a diagnosis with huge B-cell lymphoma, that have distributed to her liver. The patients condition worsened incredibly quickly but she was admitted for a liver transplant. Acute liver failure can be caused by many different conditions, including poisoning, drug-induced hepatitis, viral hepatitis, alcoholic hepatitis, autoimmune hepatitis, and hepatic malignancies. Acute liver failure is usually reversible if it is caused by an identifiable cause and if that cause can be treated.
这个病例研究是关于一个72岁的老年妇女,由于巨大的b细胞淋巴瘤扩散急性肝功能衰竭。该患者过去曾被诊断出患有这种疾病,目前正在接受治疗。然而,她开始表现出疲劳和黄疸的症状,导致住院治疗。这项研究着眼于她的病史和目前的状况,以及她的疾病是如何随着时间的推移而发展的。它还讨论了迄今为止尝试过的各种治疗方法及其对她的影响。CT显示肝脏弥漫性巨大b细胞淋巴瘤。由于病情迅速恶化,患者接受了紧急剖腹手术并切除了肝脏病变。CT扫描显示肝脏肿大(10厘米),表面呈结节状,弥漫性衰减增强。超声检查显示胆囊壁增厚。她已住院进一步评估和组织她的急性肝衰竭,由于巨大的b细胞淋巴瘤弥散。一位72岁高龄的老年妇女因巨大的b细胞淋巴瘤弥散而出现急性肝脏问题,并因这种肝移植而住院。病人被诊断为巨大的b细胞淋巴瘤,并已扩散到肝脏。病人的病情迅速恶化,但她还是接受了肝脏移植手术。急性肝衰竭可由许多不同的情况引起,包括中毒、药物性肝炎、病毒性肝炎、酒精性肝炎、自身免疫性肝炎和肝脏恶性肿瘤。急性肝衰竭通常是可逆的,如果它是由一个可识别的原因引起的,如果这个原因可以治疗。
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引用次数: 0
A Case Report on Steroid Resistant Ulcerative Colitis 类固醇抵抗性溃疡性结肠炎1例报告
Pub Date : 2022-03-15 DOI: 10.26452/fjphs.v2i2.215
Gnana Prakash
Ulcerative colitis is a chronic inflammatory bowel disease that affects the large intestine. It leads to bloody diarrhoea and pain in the lower abdomen. In a 22-year-old man with steroid resistant ulcerative colitis, doctors were faced with an unusual case where he was producing blood. The patient had no medical history of bleeding (except for blood pressure medication two years ago) and had no predisposing diseases or conditions that would explain his non-bloody diarrhoea and rectal bleeding. In this case, doctors needed to find out if this patient had any other causes of bleeding other than ulcerative colitis such as a condition involving their platelets or a vitamin K deficiency, but none were found. Ulcerative colitis is a chronic inflammatory bowel disease that can lead to serious complications. The case study in this article highlights some of these complications which were treated successfully with steroid therapy. Patients may also experience weight loss, malabsorption issues or fatigue as well as complications such as liver problems. The case study also highlights the severity of the patient's condition before diagnosis and treatment, which is why need more research on all cases like this.
溃疡性结肠炎是一种影响大肠的慢性炎症性肠病。它会导致带血腹泻和下腹疼痛。在一名22岁的患有类固醇抵抗性溃疡性结肠炎的男子中,医生遇到了一个不寻常的情况,他正在产生血液。患者无出血病史(除两年前服用降压药外),并无易感疾病或状况可解释其非血性腹泻和直肠出血。在这种情况下,医生需要找出除了溃疡性结肠炎之外,患者是否有其他出血原因,比如血小板或维生素K缺乏,但没有发现任何原因。溃疡性结肠炎是一种慢性炎症性肠病,可导致严重的并发症。在这篇文章的案例研究强调了一些这些并发症的治疗成功与类固醇治疗。患者还可能出现体重减轻、吸收不良或疲劳以及肝脏问题等并发症。该案例研究还强调了患者在诊断和治疗前病情的严重性,这就是为什么需要对所有此类病例进行更多研究的原因。
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引用次数: 0
Preparation and Characterization of Natural Face Pack 天然面膜的制备与表征
Pub Date : 2022-01-13 DOI: 10.26452/fjphs.v2i1.139
Anand Krishnan Prakash
Testing
测试
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引用次数: 0
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Future Journal of Pharmaceuticals and Health Sciences
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