Pub Date : 2024-02-07DOI: 10.1080/26895293.2024.2308904
Lekun Gui, Lijun Jin, Huangjun Liu
Cardiovascular diseases are one of the leading causes of death globally. The primary pathological mechanism in myocardial infarction and heart failure is irreversible cardiomyocyte loss. The conven...
{"title":"Cardiac regeneration: 20 years of development and update in zebrafish and mouse","authors":"Lekun Gui, Lijun Jin, Huangjun Liu","doi":"10.1080/26895293.2024.2308904","DOIUrl":"https://doi.org/10.1080/26895293.2024.2308904","url":null,"abstract":"Cardiovascular diseases are one of the leading causes of death globally. The primary pathological mechanism in myocardial infarction and heart failure is irreversible cardiomyocyte loss. The conven...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"266 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139764289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diverse species of lactic acid bacteria (LAB) are involved in the spontaneous fermentation of lait caillé, a traditional milk product from Burkina Faso. However, there is little information on the ...
{"title":"16S rRNA gene sequencing of non-lactic acid bacteria cultures from lait caillé in Burkina Faso","authors":"Geoffroy Romaric Bayili, Clarisse S. Compaoré, Bréhima Diawara, Lene Jespersen, Hagretou Sawadogo-Lingani","doi":"10.1080/26895293.2024.2309346","DOIUrl":"https://doi.org/10.1080/26895293.2024.2309346","url":null,"abstract":"Diverse species of lactic acid bacteria (LAB) are involved in the spontaneous fermentation of lait caillé, a traditional milk product from Burkina Faso. However, there is little information on the ...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139764219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hypertension (HT) is a major cause of intracerebral hemorrhage (ICH), and hypertensive cerebral hemorrhage (HCH) has a serious impact on life quality of patients and gives society a heavy burden. T...
{"title":"Analysis of differentially expressed genes in hypertension and hypertensive cerebral hemorrhage via RNA-sequencing","authors":"Hongwu Qi, Min Qiao, Yansong Liu, Weijun Zeng, Lizhao Zhang, Hongjun Guo","doi":"10.1080/26895293.2024.2304349","DOIUrl":"https://doi.org/10.1080/26895293.2024.2304349","url":null,"abstract":"Hypertension (HT) is a major cause of intracerebral hemorrhage (ICH), and hypertensive cerebral hemorrhage (HCH) has a serious impact on life quality of patients and gives society a heavy burden. T...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139483687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-16DOI: 10.1080/26895293.2024.2304338
Marwan Noori Ramadhan
Field experiments were conducted to determine the effect of tillage practices and inorganic sources of different combinations of nitrogen, phosphorus, and potassium fertilizers on some physical pro...
田间试验的目的是确定耕作方法和不同氮、磷、钾肥组合的无机来源对一些物理特性的影响。
{"title":"Assessment of the yield and yield attributing characters of oat (Avena sativa L.) grown under different tillage methods and NPK fertilizer rates in semi-arid conditions","authors":"Marwan Noori Ramadhan","doi":"10.1080/26895293.2024.2304338","DOIUrl":"https://doi.org/10.1080/26895293.2024.2304338","url":null,"abstract":"Field experiments were conducted to determine the effect of tillage practices and inorganic sources of different combinations of nitrogen, phosphorus, and potassium fertilizers on some physical pro...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139475577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-02DOI: 10.1080/26895293.2023.2299569
Ting Fu, Jianping Gong, Lei Xu, Ningning Ji
Cardiac fibroblasts (CFs) are of vital importance for post-myocardial infarction (MI) remodeling. This study explored the role of Placenta specific 8 (Plac8) in MI on the basis of single-cell RNA-S...
{"title":"Plac8 regulates the fibrogenic ability of cardiac fibroblasts in mice with myocardial infarction","authors":"Ting Fu, Jianping Gong, Lei Xu, Ningning Ji","doi":"10.1080/26895293.2023.2299569","DOIUrl":"https://doi.org/10.1080/26895293.2023.2299569","url":null,"abstract":"Cardiac fibroblasts (CFs) are of vital importance for post-myocardial infarction (MI) remodeling. This study explored the role of Placenta specific 8 (Plac8) in MI on the basis of single-cell RNA-S...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139096303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This meta-analysis examined the predictive value of admission serum and urine carboxypeptidase-B activation peptide (CAPAP) in patients with severe acute pancreatitis. PubMed, Embase, and the Cochr...
{"title":"The predictive value of admission serum and urine carboxypeptidase-B activation peptide for the severity of acute pancreatitis: a meta-analysis","authors":"Liang Dai, Wei-Yan Guo, Xing-Wei Xuan, Xiao-Dong Meng, Yin-Hua Wang, Hai-Xia Chai, Jian-Li Chen, Jun-Mao Chen, Jian-Yi Pu","doi":"10.1080/26895293.2023.2288534","DOIUrl":"https://doi.org/10.1080/26895293.2023.2288534","url":null,"abstract":"This meta-analysis examined the predictive value of admission serum and urine carboxypeptidase-B activation peptide (CAPAP) in patients with severe acute pancreatitis. PubMed, Embase, and the Cochr...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138527181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.1080/26895293.2023.2288532
Wenhan Li, Yao Tang, Danfang Wang, Jianhui Li
Owing to tumor heterogeneity and individual physiological variations, there remains a necessity to enhance the current prognosis prediction system for metastatic gastric cancer (MGC). This study ai...
{"title":"Outcomes in patients with metastatic gastric cancer: a surveillance, epidemiology, and end results program (SEER) database analysis","authors":"Wenhan Li, Yao Tang, Danfang Wang, Jianhui Li","doi":"10.1080/26895293.2023.2288532","DOIUrl":"https://doi.org/10.1080/26895293.2023.2288532","url":null,"abstract":"Owing to tumor heterogeneity and individual physiological variations, there remains a necessity to enhance the current prognosis prediction system for metastatic gastric cancer (MGC). This study ai...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"7 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138527167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.1080/26895293.2023.2288529
Congcong Zhu, Ge Yan, Manqi Hu, Zongguang Tai, Bin Fan, Pei Zhao, Xiao Miao, Quangang Zhu
Plant-derived natural compounds are desired for their anti-inflammatory properties. We investigated the chemical composition and the anti-inflammatory effects of the essential oil obtained from lea...
植物衍生的天然化合物因其抗炎特性而受到欢迎。研究了黄芪精油的化学成分和抗炎作用。
{"title":"Phytochemical profile and anti-inflammatory effect of Artemisia annua L. essential oil","authors":"Congcong Zhu, Ge Yan, Manqi Hu, Zongguang Tai, Bin Fan, Pei Zhao, Xiao Miao, Quangang Zhu","doi":"10.1080/26895293.2023.2288529","DOIUrl":"https://doi.org/10.1080/26895293.2023.2288529","url":null,"abstract":"Plant-derived natural compounds are desired for their anti-inflammatory properties. We investigated the chemical composition and the anti-inflammatory effects of the essential oil obtained from lea...","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138527158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.1007/978-3-031-23717-1
{"title":"Life in Science: Stories, Opinions and Advice for a New Generation of Scientists","authors":"","doi":"10.1007/978-3-031-23717-1","DOIUrl":"https://doi.org/10.1007/978-3-031-23717-1","url":null,"abstract":"","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"57 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91169879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-01DOI: 10.1080/21553769.2019.1670739
Jia-qing Liu, Tao Li
The CRISPR-Cas9 system, which uses sgRNA for targeting and the nuclease Cas9 for cleavage, has emerged as a versatile and efficient tool for genome engineering; the system has overcome the limitations of previous technologies and implements various gene editing strategies. The large-scale loss-of-function (LOF) gene scanning technology based on the CRISPR-Cas9 system can be utilized to reveal associations between the genotype and phenotype by inducing efficient and scalable gene perturbations throughout the whole genome. This technology is playing a breakthrough role in the exploration of genes associated with tumors and viruses and its expansion together with RNA sequencing (RNA-seq) can be used to assess multiplexed gene interactions as well as more complicated phenotypes. Here, we introduce LOF genetic screens based on CRISPR knockout (CRISPR ko) and its applications in synthetic lethality and virus-host interactions. We highlight the recent progress on combining this technique with single cell RNA-seq. We also compare the advantages and pitfalls of CRISPR variants, discuss the future perspectives of gene therapy and raise important considerations regarding off-target effects.
{"title":"CRISPR-Cas9-mediated loss-of-function screens","authors":"Jia-qing Liu, Tao Li","doi":"10.1080/21553769.2019.1670739","DOIUrl":"https://doi.org/10.1080/21553769.2019.1670739","url":null,"abstract":"The CRISPR-Cas9 system, which uses sgRNA for targeting and the nuclease Cas9 for cleavage, has emerged as a versatile and efficient tool for genome engineering; the system has overcome the limitations of previous technologies and implements various gene editing strategies. The large-scale loss-of-function (LOF) gene scanning technology based on the CRISPR-Cas9 system can be utilized to reveal associations between the genotype and phenotype by inducing efficient and scalable gene perturbations throughout the whole genome. This technology is playing a breakthrough role in the exploration of genes associated with tumors and viruses and its expansion together with RNA sequencing (RNA-seq) can be used to assess multiplexed gene interactions as well as more complicated phenotypes. Here, we introduce LOF genetic screens based on CRISPR knockout (CRISPR ko) and its applications in synthetic lethality and virus-host interactions. We highlight the recent progress on combining this technique with single cell RNA-seq. We also compare the advantages and pitfalls of CRISPR variants, discuss the future perspectives of gene therapy and raise important considerations regarding off-target effects.","PeriodicalId":12756,"journal":{"name":"Frontiers in Life Science","volume":"12 1","pages":"1 - 13"},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/21553769.2019.1670739","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42039586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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