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2007 6th International Special Topic Conference on Information Technology Applications in Biomedicine最新文献

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REM Sleep Classification with Respiration Rates 快速眼动睡眠的呼吸频率分类
G. Chung, B. H. Choi, K. Kim, Y. Lim, J. Choi, D. Jeong, K. Park
Polysomnagraphy, the method evaluating the sleep quality, is the reliable and standard method. However, to perform it, subject has to attach many sensors to their body. It seems intrusive, tangled and interrupting the subjects sleep. For the sake of monitoring the daily sleep pattern, simple method measuring the biosignal nonintrusively is needed. At that point, respiration is a beneficial signal, because it can be easily acquired by check the change of the thorax or abdomen. Respiration is one of the representatives of the reflection of the autonomic nervous system. According to the transition of the sleep stages, autonomic nervous system also changes and it can be shown by respiration. In this study, REM and non-REM sleep is classified by only using respiration for the 3 subjects. To enhance the performance, activity signal acquired by load-cell installed bed is added to divide the wake and REM sleep. At the results, hypnograms with polysomnagraphic data is compared with them. It can be seen that high correlation between the REM sleep and increasing pattern of the respiration rates.
多导睡眠描记法是一种可靠、规范的睡眠质量评价方法。然而,要完成它,受试者必须在他们的身体上安装许多传感器。这似乎是侵入性的,混乱的,打断了受试者的睡眠。为了监测日常睡眠模式,需要一种简便、无创的生物信号测量方法。此时,呼吸是一个有益的信号,因为它可以很容易地通过检查胸部或腹部的变化来获得。呼吸是自主神经系统反映的代表之一。根据睡眠阶段的过渡,自主神经系统也会发生变化,这可以通过呼吸来表现。在本研究中,快速眼动睡眠和非快速眼动睡眠仅通过对3个受试者的呼吸进行分类。为了提高实验性能,在实验床上加入称重传感器采集到的活动信号,以区分清醒和快速眼动睡眠。在结果的基础上,将多导睡眠图与多导睡眠图进行比较。可以看出,快速眼动睡眠与呼吸频率增加模式之间存在高度相关性。
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引用次数: 22
Blind Separation Methods for Image Show-through Problem 图像透显问题的盲分离方法
Xiaowei Zhang, Jianming Lu, T. Yahagi
This paper studies a image show-through problem. It happens often when we copy or scan a paper document, in which the image from the back page shows through. The images obtained on both side of the paper can be considered as mixture components, which are nonlinear mixtures of original images. In this study, we propose to use self-organizing map (SOM) and fastICA to implement separation of the image mixtures. SOM is neural network-based technique using unsupervised learning and can provide useful data representations. The separation results show that the two blind separation methods are applicable to the problem.
本文研究了一个图像透显问题。当我们复制或扫描一份纸质文件时,这种情况经常发生,其中最后一页的图像会显示出来。在纸的两面得到的图像可以看作是混合分量,是原始图像的非线性混合。在这项研究中,我们提出使用自组织映射(SOM)和fastICA来实现图像混合的分离。SOM是一种基于神经网络的无监督学习技术,可以提供有用的数据表示。分离结果表明,两种盲分离方法均适用于该问题。
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引用次数: 9
Innovative Biomedical Information Technologies for Low-cost Healthcare 低成本医疗保健的创新生物医学信息技术
Y.T. Zhang, C. Poon
Meeting the long-term healthcare needs of the growing elderly population and escalating healthcare expenditure in China pose a grim challenge to the current healthcare system and the solvency of state budgets. Therefore, there is a great need of advanced technologies for more effective and low-cost healthcare to alleviate the burden of the current healthcare system. Based on the development of technologies for designing wearable medical devices and biosensors, the new micro-TU-COME techniques (i.e. micro-Terahertz techniques, micro-Ultrasound techniques, micro-Computer tomography, micro-Optical-mechanical-electro system, micro-Magnetic resonance imaging, and micro-Electrophysiological imaging) and general medical imaging facilities, an information system that can deliver multi-level, multi-dimensional healthcare services to urban and rural citizens is proposed to bridge individuals, homes, communities, and hospitals through a four-layer (PHCH) system structure. This four-layer structure should ensure people be monitored by the new system as closely as it can, resulting in the novel transformation of the function of healthcare systems from symptoms treatment to early risk detection and even prevention. It allows people to self-monitor their health conditions at their convenience in an attempt to lighten the workload of doctors and nurses. Moreover, more people can benefit from the new technologies and system with much lower medical insurance fees due to the reduced risk of developing severe diseases through regular, long-term and effective monitoring of citizens' health conditions.
满足中国日益增长的老年人口的长期医疗需求和不断增加的医疗支出对当前的医疗体系和国家预算的偿付能力提出了严峻的挑战。因此,迫切需要先进的技术来实现更有效、更低成本的医疗保健,以减轻当前医疗保健系统的负担。基于可穿戴医疗设备和生物传感器设计技术的发展,新型微tu - come技术(即微太赫兹技术、微超声技术、微计算机断层扫描技术、微光机电系统、微磁共振成像和微电生理成像)和一般医学成像设施,一个可以提供多层次、通过四层体系结构,构建个人、家庭、社区和医院之间的桥梁,为城乡居民提供多维度医疗服务。这种四层结构应确保人们尽可能密切地受到新系统的监测,从而实现医疗保健系统功能的新转变,从症状治疗到早期风险发现甚至预防。它允许人们在方便的时候自我监测自己的健康状况,以减轻医生和护士的工作量。此外,由于通过定期、长期和有效地监测公民的健康状况,降低了患严重疾病的风险,更多的人可以从新技术和新系统中受益,医疗保险费用也会大大降低。
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引用次数: 2
Visually-Salient Region Detection in the Pixelized Image using Context-Based Model 基于上下文模型的像素化图像视觉显著区域检测
S. Jin, I.B. Lee, J.M. Han, K.S. Park
To overcome the resolution limitation in the visual prosthesis, various image processing methods have been proposed. These methods are limited for close-up images of faces or objects. However, images in real environment contain not only the predefined objects such as faces and letters but also unexpected visually-salient objects which give important information on the images. In this paper, we propose the region-of-interest detection method which is appropriate for real situations using a context-based model, and demonstrate that the detected region can guide attention. The gazes are estimated while subjects are watching two kinds of pixelized images obtained by a conventional method and the proposed method, and are compared with experimentally detected conspicuous region. The results show that the context-based model detecting visually-attractive region is useful to solve the resolution limitation.
为了克服视觉假体的分辨率限制,人们提出了各种图像处理方法。这些方法局限于人脸或物体的特写图像。然而,在真实环境中,图像中除了包含人脸、字母等预先定义好的物体外,还包含一些意想不到的视觉显著物体,这些物体为图像提供了重要的信息。本文采用基于上下文的模型,提出了一种适合于真实情境的兴趣区域检测方法,并证明了检测到的兴趣区域具有引导注意力的作用。在观察两种像素化图像时,分别对被试的视线进行估计,并与实验检测到的显著区域进行比较。结果表明,基于上下文的视觉吸引区域检测模型可以有效地解决分辨率限制问题。
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引用次数: 1
Indoor Activity Monitoring System Using an Accelerometer and Zigbee 采用加速度计和Zigbee的室内活动监测系统
Jonghee Han, Hongwon Kim, Suk-Bong Choi, K. Park
Physical activity assessment is useful for determining both physical and mental health. The measurement of activity has been performed by several techniques such as direct observations, subjective reports, metabolic measurements and portable physical activity monitors. Each type of technique has certain strengths and weaknesses. Recently, studies on portable physical activity monitors have been increasing and presented good assessment results. Upon consideration of the characteristics of the portable monitors such as being unconstrained and long-term monitoring, an indoor portable monitor was designed and developed. It measures three dimensional acceleration and transfers data by Zigbee protocol wirelessly. This system could help to assess daily activity without subject's consciousness.
身体活动评估对确定身体和精神健康都很有用。活动的测量已通过几种技术进行,如直接观察,主观报告,代谢测量和便携式身体活动监测器。每种技术都有其优缺点。近年来,对便携式身体活动监测仪的研究越来越多,并取得了良好的评价效果。考虑到便携式监测仪不受约束、监测时间长等特点,设计研制了一种室内便携式监测仪。它测量三维加速度,并通过Zigbee协议无线传输数据。该系统可以帮助评估受试者在没有意识的情况下的日常活动。
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引用次数: 6
VMOTE-II, A Biowearable Health Monitoring System 生物穿戴式健康监测系统VMOTE-II
M. Masilela, E. Hughes, C. Boanca, R. Merrell, A. Rafiq
In this paper, we present the VMOTE-II health monitoring system that measures and monitors, records and reports the vital signs of a patient to health care providers and medical personnel using both with wireless and wired technologies. This system delivers real time medical data approximately 3 times per second using medical sensors integrated in a single wearable and portable unit that is self powered. This system is geared towards patients that require 24 hour monitoring and support. VMOTE-II is a non-invasive system that would allow a patient to continue normal day to day activities with minimal inconvenience whilst providing extensive medical and physiological data.
在本文中,我们介绍了VMOTE-II健康监测系统,该系统使用无线和有线技术测量和监测、记录和报告患者的生命体征给医疗保健提供者和医务人员。该系统使用集成在单个可穿戴和便携式自供电单元中的医疗传感器,每秒提供大约3次实时医疗数据。该系统适用于需要24小时监测和支持的患者。VMOTE-II是一种非侵入性系统,允许患者在提供广泛的医疗和生理数据的同时,以最小的不便继续正常的日常活动。
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引用次数: 0
Single-trial topographic analysis of human EEG: A new `image' of event-related potentials 人类脑电图的单次试验地形分析:事件相关电位的新“图像”
M. De Lucia, C. Michel, S. Clarke, M. Murray
We present a novel approach for analyzing single-trial electroencephalography (EEG) data, using topographic information. The method allows for visualizing event-related potentials using all the electrodes of recordings overcoming the problem of previous approaches that required electrode selection and waveforms filtering. We apply this method to EEG data from an auditory object recognition experiment that we have previously analyzed at an ERP level. Temporally structured periods were statistically identified wherein a given topography predominated without any prior information about the temporal behavior. In addition to providing novel methods for EEG analysis, the data indicate that ERPs are reliably observable at a single-trial level when examined topographically.
我们提出了一种新的方法来分析单试验脑电图(EEG)数据,利用地形信息。该方法允许使用记录的所有电极来可视化事件相关电位,克服了以前需要电极选择和波形滤波的方法的问题。我们将这种方法应用于来自听觉对象识别实验的脑电图数据,我们之前在ERP水平上分析了这些数据。在统计上确定了时间结构周期,其中给定的地形占主导地位,而没有任何关于时间行为的先验信息。除了为脑电图分析提供新的方法外,数据表明,在地形检查时,在单次试验水平上可以可靠地观察到erp。
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引用次数: 15
The effect of Epimedium brevicornum Maxim (Yin Yang Huo) extract on elicitation of penile erection, and its power spectral analysis in rats 淫羊藿提取物对大鼠阴茎勃起的促进作用及其功率谱分析
Wei-Ru Han, Chih-Yuan Chuang, S. Young, K. Chen, Jiun-Hung Lin
The aim of this study is to investigate erectile response to injection administration of Epimedium brevicornum Maxim (EbM) and its power spectral analysis in rats. Adult male Sprague-Dawley (SD) rats were used in this study. Under pentobarbital sodium anesthesia, the penile Intracavernous pressure (ICP) was monitored. Intracavernous administration of doses 3000 mug/0.1 mL of EbM extract was done. Continuous power spectral analysis of electrocardiogram (ECG), blood pressure (BP) signals .Frequency-domain analysis of the stationary RR interval, systolic pressure variation was performed to quantify the high-frequency power (HF), low-frequency power (LF)-to-HF ratio (LF/HF), and normalized LF (LF%) of Heart Rate Variability (HRV), Blood Pressure Variability (BPV). The results of this study suggest that intracavernous administration of EbM extract may elicit penile erection in terms of a significant increase in ICP in the rat. These results suggest that EbM extract may facilitate decrease sympathovagal balance or to reflect sympathetic modulations activities of the heart and activities penile erection function. But have no significant differences in BPV parameters.
本研究旨在研究短角淫羊藿(Epimedium brevicorum Maxim, EbM)注射后大鼠勃起反应及其功率谱分析。本研究采用成年雄性SD大鼠。在戊巴比妥钠麻醉下,监测阴茎海绵体内压(ICP)。海绵体内给药剂量3000杯/0.1 mL的EbM提取物。对心电图(ECG)、血压(BP)信号进行连续功率谱分析。对平稳RR间期、收缩压变化进行频域分析,量化心率变异性(HRV)、血压变异性(BPV)的高频功率(HF)、低频功率(LF)与HF之比(LF/HF)和归一化LF (LF%)。本研究的结果表明,海绵体内注射EbM提取物可能会引起大鼠阴茎勃起,导致ICP显著增加。这些结果表明,EbM提取物可能有助于降低交感迷走神经平衡或反映心脏和阴茎勃起功能活动的交感调节活动。但BPV参数无显著性差异。
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引用次数: 1
Second Derivative of Photoplethysmography for Estimating Vascular Aging 用于估计血管老化的光体积脉搏波的二阶导数
H. Baek, Jung Soo Kim, Y. S. Kim, Haet Bit Lee, K. Park
Coronary artery disease (CAD) is one of the major causes of death. Therefore recurrent monitoring of arterial condition is important. The photoplethysmography (PPG) is simple and cost effective technique to measure blood volume change. As an application of PPG technique, the second derivative of photoplethysmography(SDPTG) was introduced for monitoring arterial condition. SDPTG consists of an a, b, c and d wave in systole and an e wave in diastole. The SDPTG wave pattern is determined by the proportions of the b, c, d, and e waves to the a wave. In the present study, it is confirmed that the b/a ratio and SDPTG-AI increased with age, and the c/a, d/a, and e/a ratios decreased with age. The informal method which substitutes formal SDPTG-AI was suggested.
冠状动脉疾病(CAD)是导致死亡的主要原因之一。因此,反复监测动脉状况是很重要的。光容积脉搏波(PPG)是测量血容量变化的一种简单且经济有效的技术。作为PPG技术的一个应用,介绍了光容积脉搏波的二阶导数(SDPTG)来监测动脉状况。SDPTG包括收缩期的a、b、c、d波和舒张期的e波。SDPTG波型由b波、c波、d波和e波与a波的比例决定。本研究证实b/a比和SDPTG-AI随年龄增长而增加,c/a、d/a、e/a随年龄增长而降低。提出了替代正式SDPTG-AI的非正式方法。
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引用次数: 66
A Novel Sphygmography Based on Vascular Geometry and Arterial Model 一种基于血管几何和动脉模型的新型血液学
Shing-Hong Liu, Chu-Chang Tyan, Jian-Jung Chen, Jia-Jung Wang
Previous research on the non-invasive measurement of radial pulse waveform had no standardized quantitative and qualitative procedures. The aim of this study was to propose a new non-invasive measuring apparatus that had a three-axis sphygmography and a standard positioning procedure for detecting the optimal measure site and measuring an accurate pulse waveform. The artery vessel can be viewed as a cylinder, so, during measurement, if the sensor was not placed right at the centre but at an angle, the measured waveform would be distorted. Also, the blood vessel is made of elastic material. Its compliance changes with transmural pressure. When transmural pressure is equal to zero, compliance is at its maximum. The strain gauge and pizeoresistor was used to measure the radial arterial diameter change and pulse waveform, respectively.
以往对径向脉冲波形无创测量的研究缺乏标准化的定量和定性方法。本研究的目的是提出一种新的无创测量仪器,该仪器具有三轴血压计和标准定位程序,用于检测最佳测量位置和测量准确的脉搏波形。动脉血管可以看作是一个圆柱体,因此,在测量过程中,如果传感器不是放在正中心,而是以一个角度放置,则测量的波形将会失真。此外,血管是由弹性材料制成的。其顺应性随跨壁压力的变化而变化。当跨壁压力等于零时,顺应性达到最大。用应变片和压敏电阻分别测量桡动脉直径变化和脉冲波形。
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引用次数: 0
期刊
2007 6th International Special Topic Conference on Information Technology Applications in Biomedicine
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