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Innovative landing zones for one-piece, rigidly fixated patient-specific subperiosteal implants in dental rehabilitation of severe maxillary and midfacial defects. 创新的一件式,刚性固定患者特定骨膜下种植体在牙齿康复严重上颌和面中缺损。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-18 DOI: 10.1186/s13005-025-00549-y
Nils-Claudius Gellrich, Philippe Korn, Philipp Jehn, Fritjof Lentge, Michael-Tobias Neuhaus, Björn Rahlf

Purpose of the study: This study demonstrates and investigates the feasibility of a novel approach for dental rehabilitation in complex maxillary and midfacial defects, often resulting in severe pseudo-class III relationships. It explores the use of patient-specific subperiosteal implants (IPS Implants® Preprosthetic) with innovative design variations that anchor to the skull base from below and laterally, extending beyond traditional implants to provide enhanced stability in cases of significant bone loss.

Methods: Patients with significant maxillary and midfacial bone loss due to postablative defects were included in our case series, with or without irradiation. From 100 patients, 13 required design modifications based on FEM analysis, involving implant anchorage to the lateral skull base and/or pterygoid process. Eight patients received single-sided lateral skull base extensions; one posttraumatic case required bilateral extensions. In five of 13 cases, additional extensions to the pterygoid process were implemented. One case needed both bilateral skull base and pterygoid extensions, while two had bilateral pterygoid and a single-sided skull base extension. Outcomes assessed included primary stability, prosthodontic restoration, complications, and soft tissue management.

Results: No implant failures occurred during follow-up, with functional stability established immediately post-insertion. Prosthodontic restoration succeeded in all cases, with no stability loss or periimplantitis. Mucositis was noted around posterior posts in some instances, and one bar required trimming due to soft tissue changes, without affecting implant function. One implant had to be removed, due to chronic pain.

Conclusions: Patient-specific IPS Implants® Preprosthetic with design extensions provide a biologically suitable solution for stable dental rehabilitation in severe maxillary and midfacial structure loss, without biomechanical limitations. Achieving rigid fixation distant from the soft tissue transition is crucial for success.

研究目的:本研究展示并探讨了一种用于复杂的上颌和面中部缺损的牙科康复新方法的可行性,这些缺损通常导致严重的假III类关系。它探索了患者特异性骨膜下植入物(IPS implant®preprosthesis)的使用,具有创新的设计变化,从下方和外侧固定在颅底,超越传统植入物,在严重骨质流失的情况下提供更高的稳定性。方法:我们的病例系列包括有或没有放射治疗的由于术后缺损导致的上颌和面中部骨明显丢失的患者。从100例患者中,13例需要基于FEM分析的设计修改,涉及植入物锚定到侧颅底和/或翼状突。8例患者接受单侧侧颅底延伸术;一个创伤后病例需要双侧延长。在13例中,有5例对翼状突进行了额外的扩展。1例需要双侧颅底和翼状骨延伸,2例需要双侧翼状骨和单侧颅底延伸。评估的结果包括初级稳定性、修复修复、并发症和软组织管理。结果:随访期间未发生种植体失败,植入后立即建立功能稳定性。所有病例均成功修复,无稳定性丧失或种植体周围炎。在某些情况下,后桩周围出现粘膜炎,由于软组织改变,一根棒需要修剪,但不影响种植体功能。由于慢性疼痛,一颗植入物不得不被移除。结论:具有设计扩展的患者特异性IPS implant®预修复体为严重上颌和面中结构缺失的患者提供了生物学上合适的稳定牙科康复解决方案,没有生物力学限制。实现远离软组织转移的刚性固定是成功的关键。
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引用次数: 0
Investigation of the effect of impacted third molar position and orientation on bad split fractures in sagittal split ramus osteotomy using finite element analysis. 应用有限元方法研究第三磨牙在矢状分叉支截骨术中对不良裂骨折的影响。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-16 DOI: 10.1186/s13005-025-00574-x
İrfan Üstündağ, Erkan Mecu, Yunus Çetiner, Mehmet Sait Şimşek

Background: This study aims to evaluate the impact of different angular orientations and buccolingual positions of impacted third molars on the incidence of bad splits during sagittal split ramus osteotomy using finite element analysis.

Materials and methods: A total of 12 mandibular models were constructed, each representing a unique combination of third molar orientations (vertical, distoangular, horizontal, mesioangular) and positions (buccal, lingual, central). A force of 20 N was applied from the osteotomy line toward the proximal and distal segments to simulate the working principle of the Smith Spreader instrument.

Results: The maximum principal stress followed the order: vertical > distoangular > horizontal > mesioangular. In terms of positional stress distribution, the buccal position generated the highest stress, followed by lingual and central positions. Similar trends were observed across all stress criteria evaluated.

Conclusion: The orientation and position of impacted third molars have a direct effect on the risk of bad splits during SSRO. Mesioangular and centrally positioned teeth were associated with lower stress levels, indicating lower risk, while vertically oriented and buccally or lingually positioned molars showed significantly higher stress concentrations. Thus, extraction of high-risk impacted third molars prior to surgery is recommended to reduce the likelihood of complications.

背景:本研究旨在通过有限元分析评估埋伏第三磨牙矢状分叉支截骨术中不同角度取向和颊舌位置对不良劈裂发生率的影响。材料和方法:共构建了12个下颌模型,每个模型都代表了第三磨牙的独特组合(垂直、离角、水平、中角)和位置(颊、舌、中央)。从截骨线向近段和远段施加20牛的力来模拟史密斯伸展器的工作原理。结果:最大主应力顺序为:垂直>非直角>水平>中直角。在体位应力分布方面,颊位产生的应力最大,其次是舌位和中位。在所有评估的压力标准中都观察到类似的趋势。结论:阻生第三磨牙的牙位和牙位直接影响SSRO术后发生牙裂的风险。中棱角和中心位置的磨牙应力水平较低,表明风险较低,而垂直方向和颊部或舌部位置的磨牙应力浓度明显较高。因此,建议在手术前拔除高风险阻生第三磨牙,以减少并发症的可能性。
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引用次数: 0
The role of otorhinolaryngologists in the treatment of hereditary hemorrhagic telangiectasia. 耳鼻喉科医生在遗传性出血性毛细血管扩张症治疗中的作用。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-13 DOI: 10.1186/s13005-025-00567-w
René Lehner, Robin Lochbaum, Thomas K Hoffmann, Jens Greve
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引用次数: 0
Intraoperative CT evaluation of repositioning accuracy in zygomaticomaxillary complex fractures: 1-point versus multiple-point fixation. 术中CT评价颧骨-腋窝复合骨折复位精度:1点与多点固定。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-13 DOI: 10.1186/s13005-025-00558-x
Andreas Sakkas, Johannes Schulze, Mario Scheurer, Majeed Rana, Robin Kasper, Marcel Ebeling, Alexander Schramm, Frank Wilde, Marc Knitz
<p><strong>Purpose: </strong>The increasing interest in minimally invasive procedures, which carries minimal risk for wound complications and scarring while also providing predictable outcomes, has brought attention to the concept of 1-point fixation in treating zygomaticomaxillary (ZMC) fractures. The primary aim of this study was to compare the intraoperative accuracy of repositioning following osteosynthesis with 1-point fixation versus multiple-point fixation in unilateral fractures of the ZMC complex. The secondary aim was to evaluate associations between trauma- and procedure-specific factors and the surgical outcomes of both fixation methods.</p><p><strong>Methods: </strong>In this retrospective cohort single-centre study, patients who underwent surgical treatment for unilateral ZMC fractures using either 1-point or multiple-point fixation over a 7-year period were included. Forty-two patients were treated with 1-point fixation through an intraoral Keen's approach (group 1), while 20 patients were treated with multiple-point fixation through intraoral and extraoral approach (group 2). Demographic, clinical, radiological, and treatment data were analyzed. The degree of repositioning including protrusion difference of the zygoma (height, width, diagonal), malar difference using an asymmetry index, and difference in the intraorbital volume were measured comparing preoperative and intraoperative CT imaging. Multivariable analyses were conducted to compare the surgical outcomes in both groups and identify associations between the trauma- and procedure-specific variables and the intraoperative accuracy of fracture repositioning.</p><p><strong>Results: </strong>A total of 62 patients with 62 unilateral ZMC fractures were included in the analysis. Violence was the most common mechanism of injury (n = 16; 25.8%). Forty-two patients underwent treatment with 1-point fixation, while 20 patients received multiple-point fixation. The intraoperative malar width difference and malar diagonal difference were significantly higher in group 1 (p = 0.003 / p = 0.036). No difference was detected in the intraorbital volume between the two fixation groups intraoperatively. Univariate analysis revealed that an interval between trauma-surgery of 3-7 days was significantly associated a better repositioning result in terms of intraorbital volume difference after multiple-point fixation (p = 0.03).</p><p><strong>Conclusions: </strong>This study shows that multiple-point fixation achieves superior accuracy in restoring zygomatic geometry, especially malar projection and transverse symmetry, while both techniques adequately restore intraorbital volume. Single-point fixation remains a viable, less invasive option for non-comminuted ZMC fractures when guided by intraoperative 3D imaging. The lack of revision surgeries in either group supports a tailored, fracture-specific strategy that balances precision with minimal invasiveness, consistent with trends toward individuali
目的:对微创手术的兴趣日益增加,微创手术的伤口并发症和瘢痕风险最小,同时也提供可预测的结果,这引起了人们对1点固定治疗颧腋骨折(ZMC)概念的关注。本研究的主要目的是比较单侧ZMC复合体骨折中单点固定与多点固定植骨术后复位的术中准确性。第二个目的是评估创伤和手术特异性因素与两种固定方法的手术结果之间的关系。方法:在这项回顾性队列单中心研究中,接受单侧ZMC骨折手术治疗的患者采用单点或多点固定,时间超过7年。42例患者通过口内Keen入路进行1点固定(1组),20例患者通过口内和口外入路进行多点固定(2组)。对人口学、临床、放射学和治疗数据进行分析。再定位的程度包括颧骨的突出差异(高度、宽度、对角线),颧部不对称指数的差异,以及眶内体积的差异,比较术前和术中CT成像。采用多变量分析比较两组的手术结果,并确定创伤和手术特异性变量与术中骨折复位准确性之间的关系。结果:本研究共纳入62例单侧ZMC骨折患者。暴力是最常见的伤害机制(n = 16; 25.8%)。42例采用单点固定,20例采用多点固定。术中颧骨宽度差异和颧骨的对角线差异显著高于在组1 (p = 0.003 / p = 0.036)。术中两组间眶内体积无差异。单因素分析显示,创伤-手术间隔3-7天与多点固定后更好的眶内容积差重定位结果显著相关(p = 0.03)。结论:该研究表明多点固定在恢复颧骨几何形状方面具有优越的准确性,特别是颧突和横向对称,而这两种技术都能充分恢复眶内体积。在术中3D成像的指导下,单点固定对于非粉碎性ZMC骨折仍然是一种可行的、侵入性较小的选择。两组均缺乏翻修手术,这支持了一种量身定制的骨折特异性策略,该策略平衡了精确度和最小侵入性,符合个性化、资源高效的创伤护理趋势。
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引用次数: 0
Passivity, torque stability, and fracture resistance in screw-retained and dual-retained metal-ceramic implant-supported restorations: an in vitro study, part II. 螺钉保留和双保留金属陶瓷种植体支持修复体的被动性、扭矩稳定性和抗骨折性:一项体外研究,第二部分。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-13 DOI: 10.1186/s13005-025-00575-w
Safoura Ghodsi, Sareh Habibzadeh, Marzieh Alikhasi, Seyed Ali Mosaddad, Hosein Mohebbi

Background: This study aimed to compare the passivity, screw torque stability, and fracture resistance between dual- and screw-retained implant restorations, before and after thermomechanical loading.

Methods: Twenty metal-ceramic restorations were divided into two groups (n = 10 each). Group 1 (G1) featured dual-retained restorations on prefabricated titanium abutments, while Group 2 (G2) had screw-retained restorations on UCLA chromium-cobalt cast-to abutments. Passivity, adjustment ease, and torque loss were compared, along with fracture resistance and mode, post-fabrication and after thermomechanical loading (500 thermal and 500,000 mechanical loading cycles). Independent t-tests and Mann-Whitney U tests were used to compare passivity characteristics and fracture resistance, while torque losses were analyzed using a generalized estimating equations (GEE) model with LSD post-hoc test (α = 0.05).

Results: G1 required significantly less adjustment time and frequency (P < .001) and exhibited a lower torque angle (higher passivity) (P = .001) compared to G2. In G1, the screw torque loss (%) measured 24.02 ± 3.01 before and 36.51 ± 4.28 after loading compared to the initial torque and 16.17 ± 3.67 after loading compared to the detorque value. In G2, these values were 24.76 ± 3.45, 39.9 ± 2.55, and 20.1 ± 3.96, respectively. While the rate of torque loss did not differ significantly before loading, it was significantly higher in G2 after loading (P < .05). Fracture resistance was significantly higher in G1 (P < .05). Both groups exhibited a mixed type of failure mode.

Conclusions: Dual-retained metal-ceramic restorations outperformed screw-retained counterparts, demonstrating improved passivity, lower screw torque loss percentages, and higher fracture resistance.

Clinical trial number: Not applicable.

背景:本研究旨在比较热机械载荷前后双假体和螺钉保留假体修复体的被动性、螺钉扭矩稳定性和抗骨折性。方法:20例金属陶瓷修复体分为两组,每组10例。组1 (G1)采用预制钛基牙的双固位修复体,组2 (G2)采用UCLA铬钴铸造基牙的螺钉固位修复体。比较了被动性、调整难度和扭矩损失,以及制造后和热机械加载(500次热加载和50万次机械加载)后的抗断裂性和模式。采用独立t检验和Mann-Whitney U检验比较被动特性和抗断裂性能,采用广义估计方程(GEE)模型和LSD事后检验分析扭矩损失(α = 0.05)。结果:G1所需的调整时间和频率明显减少(P)。结论:双保留金属陶瓷修复体优于螺钉保留金属陶瓷修复体,表现出更好的被动性,更低的螺钉扭矩损失百分比和更高的抗骨折性。临床试验号:不适用。
{"title":"Passivity, torque stability, and fracture resistance in screw-retained and dual-retained metal-ceramic implant-supported restorations: an in vitro study, part II.","authors":"Safoura Ghodsi, Sareh Habibzadeh, Marzieh Alikhasi, Seyed Ali Mosaddad, Hosein Mohebbi","doi":"10.1186/s13005-025-00575-w","DOIUrl":"10.1186/s13005-025-00575-w","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to compare the passivity, screw torque stability, and fracture resistance between dual- and screw-retained implant restorations, before and after thermomechanical loading.</p><p><strong>Methods: </strong>Twenty metal-ceramic restorations were divided into two groups (n = 10 each). Group 1 (G1) featured dual-retained restorations on prefabricated titanium abutments, while Group 2 (G2) had screw-retained restorations on UCLA chromium-cobalt cast-to abutments. Passivity, adjustment ease, and torque loss were compared, along with fracture resistance and mode, post-fabrication and after thermomechanical loading (500 thermal and 500,000 mechanical loading cycles). Independent t-tests and Mann-Whitney U tests were used to compare passivity characteristics and fracture resistance, while torque losses were analyzed using a generalized estimating equations (GEE) model with LSD post-hoc test (α = 0.05).</p><p><strong>Results: </strong>G1 required significantly less adjustment time and frequency (P < .001) and exhibited a lower torque angle (higher passivity) (P = .001) compared to G2. In G1, the screw torque loss (%) measured 24.02 ± 3.01 before and 36.51 ± 4.28 after loading compared to the initial torque and 16.17 ± 3.67 after loading compared to the detorque value. In G2, these values were 24.76 ± 3.45, 39.9 ± 2.55, and 20.1 ± 3.96, respectively. While the rate of torque loss did not differ significantly before loading, it was significantly higher in G2 after loading (P < .05). Fracture resistance was significantly higher in G1 (P < .05). Both groups exhibited a mixed type of failure mode.</p><p><strong>Conclusions: </strong>Dual-retained metal-ceramic restorations outperformed screw-retained counterparts, demonstrating improved passivity, lower screw torque loss percentages, and higher fracture resistance.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":"6"},"PeriodicalIF":2.4,"publicationDate":"2025-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12822276/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145751790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
On the necessity of complete caries excavation: a narrative review. 全面挖掘龋洞的必要性:一种叙事回顾。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-12 DOI: 10.1186/s13005-025-00573-y
Till Dammaschke
{"title":"On the necessity of complete caries excavation: a narrative review.","authors":"Till Dammaschke","doi":"10.1186/s13005-025-00573-y","DOIUrl":"10.1186/s13005-025-00573-y","url":null,"abstract":"","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":"5"},"PeriodicalIF":2.4,"publicationDate":"2025-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12817796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145742208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Zirconia vs. titanium dental implants in maxillofacial trauma: a preliminary comparative biomechanical analysis in the maxilla using the finite element method. 氧化锆与钛牙种植体在颌面外伤中的应用:用有限元法对上颌生物力学的初步比较分析。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-06 DOI: 10.1186/s13005-025-00556-z
Stefan Krennmair, Lukas Postl, Christoph Staudigl, Michael Malek, Sven Otto, Markus Hof

Introduction: With increasing life expectancy and physical activity, patients with dental implants face a growing lifetime risk of traumatic injury. In this context, the present study aimed to evaluate and compare the traumatic biomechanical effects between titanium and zirconia single dental implant in maxillary central incisor localization exposed to frontal maxillofacial trauma.

Materials and methods: In a 3D-FEA study design, maxillary models with titanium (model-A-IT) and zirconia (model-A-IZ) implants in region 21 and a bone model without dental implant (model-B) were subjected to a frontal traumatic load of 2000 N. The von Mises stress for all 3 models was measured at a predefined cortical peri-implant region of interest (ROI) and the stress values evaluated were compared between the models. Additionally, the maximum stress values within the implants were recorded and compared for the titanium and zirconia implants.

Results: The peri-implant cortical stress value/cortical fracture risk increased significantly for both implant models (model-A-IT, model-A-IZ) as compared to the implant-free bone model (model-A-IT/model-A-IZ vs. model-B; p < 0, 001); however, no difference between the two implant models evaluated (model-A-IT vs. model-A-IZ; P = 0.806) was seen. The stress values within the dental implants measured showed a higher maximum stress peak for the zirconia implant (IZ: 1137 MPa) than for titanium implant model (IT: 686.7 MPa).

Conclusion: When exposed to frontal trauma application both implant materials showed similar effects on cortical peri-implant bone; however, zirconia dental implants provide for a significantly higher maximum stress value within the implant than titanium implants representing a higher risk of fracture.

导言:随着预期寿命和体力活动的增加,种植牙患者面临着越来越大的创伤性损伤风险。在此背景下,本研究旨在评估和比较钛和氧化锆单牙种植体在上颌中切牙定位暴露于额颌面外伤时的创伤生物力学效应。材料和方法:在3D-FEA研究设计中,上颌模型在21区植入钛(模型a - it)和氧化锆(模型a - iz),骨模型不植入牙种植体(模型b),承受2000 n的额部创伤负荷。在预先确定的皮质种植体周围感兴趣区域(ROI)测量所有3个模型的von Mises应力,并比较模型之间的应力值。此外,记录种植体内的最大应力值,并对钛和氧化锆种植体进行比较。结果:两种种植体模型(a - it模型、a - iz模型)与无种植体骨模型(a - it模型/ a - iz模型与b模型)相比,种植体周围皮质应力值/皮质骨折风险均显著增加;然而,氧化锆牙种植体在种植体内提供的最大应力值明显高于钛种植体,这意味着更高的骨折风险。
{"title":"Zirconia vs. titanium dental implants in maxillofacial trauma: a preliminary comparative biomechanical analysis in the maxilla using the finite element method.","authors":"Stefan Krennmair, Lukas Postl, Christoph Staudigl, Michael Malek, Sven Otto, Markus Hof","doi":"10.1186/s13005-025-00556-z","DOIUrl":"10.1186/s13005-025-00556-z","url":null,"abstract":"<p><strong>Introduction: </strong>With increasing life expectancy and physical activity, patients with dental implants face a growing lifetime risk of traumatic injury. In this context, the present study aimed to evaluate and compare the traumatic biomechanical effects between titanium and zirconia single dental implant in maxillary central incisor localization exposed to frontal maxillofacial trauma.</p><p><strong>Materials and methods: </strong>In a 3D-FEA study design, maxillary models with titanium (model-A-IT) and zirconia (model-A-IZ) implants in region 21 and a bone model without dental implant (model-B) were subjected to a frontal traumatic load of 2000 N. The von Mises stress for all 3 models was measured at a predefined cortical peri-implant region of interest (ROI) and the stress values evaluated were compared between the models. Additionally, the maximum stress values within the implants were recorded and compared for the titanium and zirconia implants.</p><p><strong>Results: </strong>The peri-implant cortical stress value/cortical fracture risk increased significantly for both implant models (model-A-IT, model-A-IZ) as compared to the implant-free bone model (model-A-IT/model-A-IZ vs. model-B; p < 0, 001); however, no difference between the two implant models evaluated (model-A-IT vs. model-A-IZ; P = 0.806) was seen. The stress values within the dental implants measured showed a higher maximum stress peak for the zirconia implant (IZ: 1137 MPa) than for titanium implant model (IT: 686.7 MPa).</p><p><strong>Conclusion: </strong>When exposed to frontal trauma application both implant materials showed similar effects on cortical peri-implant bone; however, zirconia dental implants provide for a significantly higher maximum stress value within the implant than titanium implants representing a higher risk of fracture.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":"4"},"PeriodicalIF":2.4,"publicationDate":"2025-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12805757/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145695820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functional tongue reconstruction using innervated TDAP versus ALT free flaps: a retrospective paired-cohort study. 使用神经支配的TDAP与ALT游离皮瓣重建舌功能:回顾性配对队列研究。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-05 DOI: 10.1186/s13005-025-00572-z
Fan Wu, Xin Xia, Chuandong Zhu, Min Fu, Xianbei Zhu, Junhui Wang, Tianjun Lan, Youyuan Wang

Objectives: To compare the postoperative complications, speech function, quality of life (QoL), overall clinical outcomes and flap volume loss of tongue reconstruction using anterolateral thigh (ALT) versus innervated-thoracodorsal artery perforator (iTDAP) flaps following hemiglossectomy for tongue squamous cell carcinoma (TSCC).

Materials and methods: Clinical data of 130 TSCC patients who underwent tongue reconstruction with ALT or iTDAP flaps were retrospectively analyzed. We compared two types of free flaps in terms of their characteristics and associated postoperative complications (including fistula, hematoma, infection, dehiscence and lower-limb venous thrombosis). Flap volume loss was assessed based on intraoperative and postoperative measurements. The University of Washington Quality of Life (UW-QOL) questionnaire, Speech Handicap Index (SHI) questionnaire and Vancouver Scar Scale (VSS) were used to evaluate quality of life (QoL), speech function and scar appearance at 3, 6 and 12 months postoperatively.

Results: The harvest time and length of the vascularized pedicle with vessels of a similar diameter were similar between the iTDAP and ALT groups (p > 0.05). Additionally, the postoperative complication rate and scar appearance were not significantly different between patients who underwent reconstruction with iTDAP flaps and those who underwent reconstruction with ALT flaps (p > 0.05). Notably, iTDAP flap recipients presented significantly improved QoL scores, higher SHI scores and shorter durations of bed rest (p < 0.05). Furthermore, flap volume loss was significantly lower in the iTDAP group compared with the ALT group (p < 0.05).

Conclusion: ITDAP flaps provide similar safety and complication rates as ALT flaps while offering better quality of life, improved speech function, shorter recovery times and lower flap volume loss, making them a viable alternative for functional tongue reconstruction.

Trial registration: The study was retrospectively registered at ClinicalTrials.gov (registration number: NCT06599801) on September 30, 2024.

目的:比较半失联舌鳞癌(TSCC)切除术后采用股前外侧(ALT)皮瓣与神经胸背动脉穿支(iTDAP)皮瓣重建舌的术后并发症、语言功能、生活质量(QoL)、总体临床结果和皮瓣体积损失。材料与方法:回顾性分析130例TSCC患者行ALT或iTDAP皮瓣舌重建的临床资料。我们比较了两种类型的自由皮瓣的特点和相关的术后并发症(包括瘘、血肿、感染、开裂和下肢静脉血栓形成)。根据术中和术后测量评估皮瓣体积损失。采用华盛顿大学生活质量(UW-QOL)问卷、语言障碍指数(SHI)问卷和温哥华疤痕量表(VSS)分别于术后3、6、12个月对患者的生活质量(QoL)、语言功能和疤痕外观进行评估。结果:iTDAP组与ALT组血管带蒂的收获时间和长度相似(p < 0.05)。此外,iTDAP皮瓣重建组与ALT皮瓣重建组的术后并发症发生率和瘢痕外观无显著差异(p < 0.05)。值得注意的是,iTDAP皮瓣受者的生活质量评分明显提高,SHI评分更高,卧床休息时间更短(p结论:iTDAP皮瓣与ALT皮瓣具有相似的安全性和并发症发生率,同时提供更好的生活质量,改善语言功能,更短的恢复时间和更小的皮瓣体积损失,使其成为功能性舌重建的可行选择。试验注册:该研究于2024年9月30日在ClinicalTrials.gov上回顾性注册(注册号:NCT06599801)。
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引用次数: 0
Unilateral and bilateral ex vivo cleft lip models: universal tools for surgical training at different levels of experience. 单侧和双侧离体唇裂模型:不同水平经验的外科训练通用工具。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-04 DOI: 10.1186/s13005-025-00565-y
Christoph Vogl, Katja L Schulz, Manuel Olmos, Manuel Weber, Tobias Möst, Marco R Kesting, Rainer Lutz

Introduction: Our group has recently established the first ex vivo cadaveric models to simulate unilateral and bilateral cleft lip surgery. We have shown that these porcine snout disc models are suitable for novice cleft surgeons to understand the basic principles of cleft lip surgery and to practice the essential surgical steps. In this study we want to show that the ex vivo cleft lip models are not only suitable and helpful for residents, but also for students and experienced surgeons with and without experience in cleft surgery.

Methods: Three courses were held to evaluate the ex vivo cleft lip models: One for oral and maxillofacial surgeons from German cleft centers and two courses for dental students. All operated on the unilateral and bilateral ex vivo cleft lip models using the Millard technique. Questionnaires were used to assess their subjective opinion of the ex vivo cleft lip models. Tasks for the students were carried out to objectify their learning success. Three-dimensional scans were taken and analyzed using a previously validated intraoral scanner to objectively assess the outcome.

Results: The ex vivo cleft lip models are suitable for the training of students and experienced surgeons with varying levels of experience in cleft lip repair. Both models were rated as realistic in terms of tissue resemblance, surgical planning, and surgical management. In addition, the specialists rated the models as realistic overall. The models also provide students with several advantages, such as improved surgical skills and a better understanding of cleft surgery. Participants felt that the models should be made available not only to residents, but also to consultants and senior consultants and should be implicated in the dental curriculum.

Conclusion: The ex vivo cleft lip models made of porcine snout discs are suitable for a wide range of users starting from students to experienced surgeons to train in cleft lip surgery. The great advantage of these models is that experienced surgeons can work with an inexpensive and readily available model to improve their skills and modify their techniques.

简介:本课组首次建立了模拟单侧和双侧唇裂手术的离体尸体模型。我们已经证明,这些猪鼻盘模型适合新手唇裂外科医生了解唇裂手术的基本原理,并练习必要的手术步骤。在本研究中,我们希望证明离体唇裂模型不仅适用于住院医师,也适用于学生和有或没有唇裂手术经验的经验丰富的外科医生。方法:采用德国唇裂中心的口腔颌面外科医生和牙科专业学生为对象,对离体唇裂模型进行评价。采用Millard技术对单侧和双侧离体唇裂模型进行手术。采用问卷调查的方式评估他们对离体唇裂模型的主观看法。为学生们完成任务,使他们的学习成功具体化。三维扫描和分析使用先前验证的口内扫描仪客观评估结果。结果:离体唇裂模型适合于学生和具有不同程度唇裂修复经验的外科医生的培训。两种模型在组织相似性、手术计划和手术管理方面都被评为现实的。此外,专家们认为这些模型总体上是现实的。这些模型也为学生提供了一些好处,比如提高了手术技巧,更好地理解了唇腭裂手术。与会者认为,这些模型不仅应提供给住院医生,也应提供给顾问和高级顾问,并应纳入牙科课程。结论:猪鼻盘制作的离体唇裂模型适用于从学生到经验丰富的外科医生进行唇裂手术训练的广泛用户。这些模型的最大优点是,经验丰富的外科医生可以使用廉价和现成的模型来提高他们的技能和修改他们的技术。
{"title":"Unilateral and bilateral ex vivo cleft lip models: universal tools for surgical training at different levels of experience.","authors":"Christoph Vogl, Katja L Schulz, Manuel Olmos, Manuel Weber, Tobias Möst, Marco R Kesting, Rainer Lutz","doi":"10.1186/s13005-025-00565-y","DOIUrl":"10.1186/s13005-025-00565-y","url":null,"abstract":"<p><strong>Introduction: </strong>Our group has recently established the first ex vivo cadaveric models to simulate unilateral and bilateral cleft lip surgery. We have shown that these porcine snout disc models are suitable for novice cleft surgeons to understand the basic principles of cleft lip surgery and to practice the essential surgical steps. In this study we want to show that the ex vivo cleft lip models are not only suitable and helpful for residents, but also for students and experienced surgeons with and without experience in cleft surgery.</p><p><strong>Methods: </strong>Three courses were held to evaluate the ex vivo cleft lip models: One for oral and maxillofacial surgeons from German cleft centers and two courses for dental students. All operated on the unilateral and bilateral ex vivo cleft lip models using the Millard technique. Questionnaires were used to assess their subjective opinion of the ex vivo cleft lip models. Tasks for the students were carried out to objectify their learning success. Three-dimensional scans were taken and analyzed using a previously validated intraoral scanner to objectively assess the outcome.</p><p><strong>Results: </strong>The ex vivo cleft lip models are suitable for the training of students and experienced surgeons with varying levels of experience in cleft lip repair. Both models were rated as realistic in terms of tissue resemblance, surgical planning, and surgical management. In addition, the specialists rated the models as realistic overall. The models also provide students with several advantages, such as improved surgical skills and a better understanding of cleft surgery. Participants felt that the models should be made available not only to residents, but also to consultants and senior consultants and should be implicated in the dental curriculum.</p><p><strong>Conclusion: </strong>The ex vivo cleft lip models made of porcine snout discs are suitable for a wide range of users starting from students to experienced surgeons to train in cleft lip surgery. The great advantage of these models is that experienced surgeons can work with an inexpensive and readily available model to improve their skills and modify their techniques.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":"86"},"PeriodicalIF":2.4,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12702147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lessening the erosive influence of electrolyte sports drinks on teeth using L-arginine and aqueous Miswak extract. 利用l -精氨酸和水萃取物减少电解质运动饮料对牙齿的侵蚀作用。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-29 DOI: 10.1186/s13005-025-00560-3
Hanaa Elgamily, Engie Safwat, Reham Sayed, Samah Mosbah, Ahmed Yossef

Objective: Excessive intake of electrolyte sports drinks (ESDs) among adolescents and athletes is associated with dental erosion due to their low pH, while their sugar content increases the risk of dental caries. This study aimed to evaluate and compare the protective effects of incorporating either L-arginine or Salvadora persica (Miswak) extract into an ESD on enamel surface properties.

Materials and methods: Extracted human premolars were randomly assigned to three groups (n = 6): (1) plain ESD, (2) ESD with 1% L-arginine (Arg-ESD), and (3) ESD with 10% Salvadora persica extract (Mis-ESD). Each specimen was immersed in its respective solution for 5 min daily over 7 days. Post-treatment assessments included enamel microhardness (VHN), surface roughness (Sa), colour change (ΔE), Ca/P ratio, and scanning electron microscopy (SEM) for surface morphology. A taste acceptability survey was conducted in adult volunteers. Statistical analysis used one-way ANOVA (α = 0.05). In addition, a small panel of adult volunteers (n = 20) evaluated the taste acceptability of the modified formulations after providing informed consent.

Results: Both Arg-ESD and Mis-ESD significantly increased enamel microhardness and reduced surface roughness compared to plain ESD (P < 0.01), with Mis-ESD showing the greatest improvements. Mis-ESD also enhanced colour stability (P < 0.001). SEM images confirmed preservation of enamel structure, particularly in Mis-ESD specimens. Taste testing indicated good palatability for both modified formulations.

Conclusion: Incorporating Salvadora persica extract into ESDs significantly improved enamel resistance to erosion and enhanced aesthetic properties. Miswak-enriched ESDs could serve as a preventive option for dental erosion.

Clinical relevance: Formulating ESDs with Salvadora persica may reduce their erosive potential while preserving taste acceptability, offering a novel, consumer-friendly strategy to protect enamel in high-risk populations.

目的:青少年和运动员过量摄入电解质运动饮料(ESDs)因其pH值低而与牙齿侵蚀有关,而其含糖量增加了龋齿的风险。本研究旨在评估和比较将l -精氨酸或木耳提取物加入到ESD中对牙釉质表面特性的保护作用。材料与方法:将提取的人前磨牙随机分为3组(n = 6):(1)普通ESD组,(2)1% l -精氨酸ESD组(Arg-ESD),(3) 10%木耳提取物ESD组(miss -ESD)。每个标本在各自的溶液中浸泡5分钟,持续7天。处理后的评估包括牙釉质显微硬度(VHN)、表面粗糙度(Sa)、颜色变化(ΔE)、Ca/P比和扫描电子显微镜(SEM)的表面形貌。对成年志愿者进行了味觉接受度调查。统计学分析采用单因素方差分析(α = 0.05)。此外,一小组成年志愿者(n = 20)在提供知情同意后评估了修改配方的口味可接受性。结果:与普通ESD相比,Arg-ESD和miss -ESD均显著提高了牙釉质的显微硬度,降低了表面粗糙度(P结论:将木耳提取物加入到ESD中可以显著提高牙釉质的抗侵蚀能力,增强了美观性。miswake富集的esd可以作为牙齿侵蚀的预防选择。临床意义:用胡桃木配制esd可以减少其侵蚀潜力,同时保持味道的可接受性,为保护高危人群的牙釉质提供了一种新颖的、消费者友好的策略。
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Head & Face Medicine
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