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Passivity, torque stability, and fracture resistance in screw-retained and dual-retained metal-ceramic implant-supported restorations: an in vitro study, part II. 螺钉保留和双保留金属陶瓷种植体支持修复体的被动性、扭矩稳定性和抗骨折性:一项体外研究,第二部分。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-13 DOI: 10.1186/s13005-025-00575-w
Safoura Ghodsi, Sareh Habibzadeh, Marzieh Alikhasi, Seyed Ali Mosaddad, Hosein Mohebbi

Background: This study aimed to compare the passivity, screw torque stability, and fracture resistance between dual- and screw-retained implant restorations, before and after thermomechanical loading.

Methods: Twenty metal-ceramic restorations were divided into two groups (n = 10 each). Group 1 (G1) featured dual-retained restorations on prefabricated titanium abutments, while Group 2 (G2) had screw-retained restorations on UCLA chromium-cobalt cast-to abutments. Passivity, adjustment ease, and torque loss were compared, along with fracture resistance and mode, post-fabrication and after thermomechanical loading (500 thermal and 500,000 mechanical loading cycles). Independent t-tests and Mann-Whitney U tests were used to compare passivity characteristics and fracture resistance, while torque losses were analyzed using a generalized estimating equations (GEE) model with LSD post-hoc test (α = 0.05).

Results: G1 required significantly less adjustment time and frequency (P < .001) and exhibited a lower torque angle (higher passivity) (P = .001) compared to G2. In G1, the screw torque loss (%) measured 24.02 ± 3.01 before and 36.51 ± 4.28 after loading compared to the initial torque and 16.17 ± 3.67 after loading compared to the detorque value. In G2, these values were 24.76 ± 3.45, 39.9 ± 2.55, and 20.1 ± 3.96, respectively. While the rate of torque loss did not differ significantly before loading, it was significantly higher in G2 after loading (P < .05). Fracture resistance was significantly higher in G1 (P < .05). Both groups exhibited a mixed type of failure mode.

Conclusions: Dual-retained metal-ceramic restorations outperformed screw-retained counterparts, demonstrating improved passivity, lower screw torque loss percentages, and higher fracture resistance.

Clinical trial number: Not applicable.

背景:本研究旨在比较热机械载荷前后双假体和螺钉保留假体修复体的被动性、螺钉扭矩稳定性和抗骨折性。方法:20例金属陶瓷修复体分为两组,每组10例。组1 (G1)采用预制钛基牙的双固位修复体,组2 (G2)采用UCLA铬钴铸造基牙的螺钉固位修复体。比较了被动性、调整难度和扭矩损失,以及制造后和热机械加载(500次热加载和50万次机械加载)后的抗断裂性和模式。采用独立t检验和Mann-Whitney U检验比较被动特性和抗断裂性能,采用广义估计方程(GEE)模型和LSD事后检验分析扭矩损失(α = 0.05)。结果:G1所需的调整时间和频率明显减少(P)。结论:双保留金属陶瓷修复体优于螺钉保留金属陶瓷修复体,表现出更好的被动性,更低的螺钉扭矩损失百分比和更高的抗骨折性。临床试验号:不适用。
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引用次数: 0
On the necessity of complete caries excavation: a narrative review. 全面挖掘龋洞的必要性:一种叙事回顾。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-12 DOI: 10.1186/s13005-025-00573-y
Till Dammaschke
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引用次数: 0
Zirconia vs. titanium dental implants in maxillofacial trauma: a preliminary comparative biomechanical analysis in the maxilla using the finite element method. 氧化锆与钛牙种植体在颌面外伤中的应用:用有限元法对上颌生物力学的初步比较分析。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-06 DOI: 10.1186/s13005-025-00556-z
Stefan Krennmair, Lukas Postl, Christoph Staudigl, Michael Malek, Sven Otto, Markus Hof

Introduction: With increasing life expectancy and physical activity, patients with dental implants face a growing lifetime risk of traumatic injury. In this context, the present study aimed to evaluate and compare the traumatic biomechanical effects between titanium and zirconia single dental implant in maxillary central incisor localization exposed to frontal maxillofacial trauma.

Materials and methods: In a 3D-FEA study design, maxillary models with titanium (model-A-IT) and zirconia (model-A-IZ) implants in region 21 and a bone model without dental implant (model-B) were subjected to a frontal traumatic load of 2000 N. The von Mises stress for all 3 models was measured at a predefined cortical peri-implant region of interest (ROI) and the stress values evaluated were compared between the models. Additionally, the maximum stress values within the implants were recorded and compared for the titanium and zirconia implants.

Results: The peri-implant cortical stress value/cortical fracture risk increased significantly for both implant models (model-A-IT, model-A-IZ) as compared to the implant-free bone model (model-A-IT/model-A-IZ vs. model-B; p < 0, 001); however, no difference between the two implant models evaluated (model-A-IT vs. model-A-IZ; P = 0.806) was seen. The stress values within the dental implants measured showed a higher maximum stress peak for the zirconia implant (IZ: 1137 MPa) than for titanium implant model (IT: 686.7 MPa).

Conclusion: When exposed to frontal trauma application both implant materials showed similar effects on cortical peri-implant bone; however, zirconia dental implants provide for a significantly higher maximum stress value within the implant than titanium implants representing a higher risk of fracture.

导言:随着预期寿命和体力活动的增加,种植牙患者面临着越来越大的创伤性损伤风险。在此背景下,本研究旨在评估和比较钛和氧化锆单牙种植体在上颌中切牙定位暴露于额颌面外伤时的创伤生物力学效应。材料和方法:在3D-FEA研究设计中,上颌模型在21区植入钛(模型a - it)和氧化锆(模型a - iz),骨模型不植入牙种植体(模型b),承受2000 n的额部创伤负荷。在预先确定的皮质种植体周围感兴趣区域(ROI)测量所有3个模型的von Mises应力,并比较模型之间的应力值。此外,记录种植体内的最大应力值,并对钛和氧化锆种植体进行比较。结果:两种种植体模型(a - it模型、a - iz模型)与无种植体骨模型(a - it模型/ a - iz模型与b模型)相比,种植体周围皮质应力值/皮质骨折风险均显著增加;然而,氧化锆牙种植体在种植体内提供的最大应力值明显高于钛种植体,这意味着更高的骨折风险。
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引用次数: 0
Functional tongue reconstruction using innervated TDAP versus ALT free flaps: a retrospective paired-cohort study. 使用神经支配的TDAP与ALT游离皮瓣重建舌功能:回顾性配对队列研究。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-05 DOI: 10.1186/s13005-025-00572-z
Fan Wu, Xin Xia, Chuandong Zhu, Min Fu, Xianbei Zhu, Junhui Wang, Tianjun Lan, Youyuan Wang

Objectives: To compare the postoperative complications, speech function, quality of life (QoL), overall clinical outcomes and flap volume loss of tongue reconstruction using anterolateral thigh (ALT) versus innervated-thoracodorsal artery perforator (iTDAP) flaps following hemiglossectomy for tongue squamous cell carcinoma (TSCC).

Materials and methods: Clinical data of 130 TSCC patients who underwent tongue reconstruction with ALT or iTDAP flaps were retrospectively analyzed. We compared two types of free flaps in terms of their characteristics and associated postoperative complications (including fistula, hematoma, infection, dehiscence and lower-limb venous thrombosis). Flap volume loss was assessed based on intraoperative and postoperative measurements. The University of Washington Quality of Life (UW-QOL) questionnaire, Speech Handicap Index (SHI) questionnaire and Vancouver Scar Scale (VSS) were used to evaluate quality of life (QoL), speech function and scar appearance at 3, 6 and 12 months postoperatively.

Results: The harvest time and length of the vascularized pedicle with vessels of a similar diameter were similar between the iTDAP and ALT groups (p > 0.05). Additionally, the postoperative complication rate and scar appearance were not significantly different between patients who underwent reconstruction with iTDAP flaps and those who underwent reconstruction with ALT flaps (p > 0.05). Notably, iTDAP flap recipients presented significantly improved QoL scores, higher SHI scores and shorter durations of bed rest (p < 0.05). Furthermore, flap volume loss was significantly lower in the iTDAP group compared with the ALT group (p < 0.05).

Conclusion: ITDAP flaps provide similar safety and complication rates as ALT flaps while offering better quality of life, improved speech function, shorter recovery times and lower flap volume loss, making them a viable alternative for functional tongue reconstruction.

Trial registration: The study was retrospectively registered at ClinicalTrials.gov (registration number: NCT06599801) on September 30, 2024.

目的:比较半失联舌鳞癌(TSCC)切除术后采用股前外侧(ALT)皮瓣与神经胸背动脉穿支(iTDAP)皮瓣重建舌的术后并发症、语言功能、生活质量(QoL)、总体临床结果和皮瓣体积损失。材料与方法:回顾性分析130例TSCC患者行ALT或iTDAP皮瓣舌重建的临床资料。我们比较了两种类型的自由皮瓣的特点和相关的术后并发症(包括瘘、血肿、感染、开裂和下肢静脉血栓形成)。根据术中和术后测量评估皮瓣体积损失。采用华盛顿大学生活质量(UW-QOL)问卷、语言障碍指数(SHI)问卷和温哥华疤痕量表(VSS)分别于术后3、6、12个月对患者的生活质量(QoL)、语言功能和疤痕外观进行评估。结果:iTDAP组与ALT组血管带蒂的收获时间和长度相似(p < 0.05)。此外,iTDAP皮瓣重建组与ALT皮瓣重建组的术后并发症发生率和瘢痕外观无显著差异(p < 0.05)。值得注意的是,iTDAP皮瓣受者的生活质量评分明显提高,SHI评分更高,卧床休息时间更短(p结论:iTDAP皮瓣与ALT皮瓣具有相似的安全性和并发症发生率,同时提供更好的生活质量,改善语言功能,更短的恢复时间和更小的皮瓣体积损失,使其成为功能性舌重建的可行选择。试验注册:该研究于2024年9月30日在ClinicalTrials.gov上回顾性注册(注册号:NCT06599801)。
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引用次数: 0
Unilateral and bilateral ex vivo cleft lip models: universal tools for surgical training at different levels of experience. 单侧和双侧离体唇裂模型:不同水平经验的外科训练通用工具。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-12-04 DOI: 10.1186/s13005-025-00565-y
Christoph Vogl, Katja L Schulz, Manuel Olmos, Manuel Weber, Tobias Möst, Marco R Kesting, Rainer Lutz

Introduction: Our group has recently established the first ex vivo cadaveric models to simulate unilateral and bilateral cleft lip surgery. We have shown that these porcine snout disc models are suitable for novice cleft surgeons to understand the basic principles of cleft lip surgery and to practice the essential surgical steps. In this study we want to show that the ex vivo cleft lip models are not only suitable and helpful for residents, but also for students and experienced surgeons with and without experience in cleft surgery.

Methods: Three courses were held to evaluate the ex vivo cleft lip models: One for oral and maxillofacial surgeons from German cleft centers and two courses for dental students. All operated on the unilateral and bilateral ex vivo cleft lip models using the Millard technique. Questionnaires were used to assess their subjective opinion of the ex vivo cleft lip models. Tasks for the students were carried out to objectify their learning success. Three-dimensional scans were taken and analyzed using a previously validated intraoral scanner to objectively assess the outcome.

Results: The ex vivo cleft lip models are suitable for the training of students and experienced surgeons with varying levels of experience in cleft lip repair. Both models were rated as realistic in terms of tissue resemblance, surgical planning, and surgical management. In addition, the specialists rated the models as realistic overall. The models also provide students with several advantages, such as improved surgical skills and a better understanding of cleft surgery. Participants felt that the models should be made available not only to residents, but also to consultants and senior consultants and should be implicated in the dental curriculum.

Conclusion: The ex vivo cleft lip models made of porcine snout discs are suitable for a wide range of users starting from students to experienced surgeons to train in cleft lip surgery. The great advantage of these models is that experienced surgeons can work with an inexpensive and readily available model to improve their skills and modify their techniques.

简介:本课组首次建立了模拟单侧和双侧唇裂手术的离体尸体模型。我们已经证明,这些猪鼻盘模型适合新手唇裂外科医生了解唇裂手术的基本原理,并练习必要的手术步骤。在本研究中,我们希望证明离体唇裂模型不仅适用于住院医师,也适用于学生和有或没有唇裂手术经验的经验丰富的外科医生。方法:采用德国唇裂中心的口腔颌面外科医生和牙科专业学生为对象,对离体唇裂模型进行评价。采用Millard技术对单侧和双侧离体唇裂模型进行手术。采用问卷调查的方式评估他们对离体唇裂模型的主观看法。为学生们完成任务,使他们的学习成功具体化。三维扫描和分析使用先前验证的口内扫描仪客观评估结果。结果:离体唇裂模型适合于学生和具有不同程度唇裂修复经验的外科医生的培训。两种模型在组织相似性、手术计划和手术管理方面都被评为现实的。此外,专家们认为这些模型总体上是现实的。这些模型也为学生提供了一些好处,比如提高了手术技巧,更好地理解了唇腭裂手术。与会者认为,这些模型不仅应提供给住院医生,也应提供给顾问和高级顾问,并应纳入牙科课程。结论:猪鼻盘制作的离体唇裂模型适用于从学生到经验丰富的外科医生进行唇裂手术训练的广泛用户。这些模型的最大优点是,经验丰富的外科医生可以使用廉价和现成的模型来提高他们的技能和修改他们的技术。
{"title":"Unilateral and bilateral ex vivo cleft lip models: universal tools for surgical training at different levels of experience.","authors":"Christoph Vogl, Katja L Schulz, Manuel Olmos, Manuel Weber, Tobias Möst, Marco R Kesting, Rainer Lutz","doi":"10.1186/s13005-025-00565-y","DOIUrl":"10.1186/s13005-025-00565-y","url":null,"abstract":"<p><strong>Introduction: </strong>Our group has recently established the first ex vivo cadaveric models to simulate unilateral and bilateral cleft lip surgery. We have shown that these porcine snout disc models are suitable for novice cleft surgeons to understand the basic principles of cleft lip surgery and to practice the essential surgical steps. In this study we want to show that the ex vivo cleft lip models are not only suitable and helpful for residents, but also for students and experienced surgeons with and without experience in cleft surgery.</p><p><strong>Methods: </strong>Three courses were held to evaluate the ex vivo cleft lip models: One for oral and maxillofacial surgeons from German cleft centers and two courses for dental students. All operated on the unilateral and bilateral ex vivo cleft lip models using the Millard technique. Questionnaires were used to assess their subjective opinion of the ex vivo cleft lip models. Tasks for the students were carried out to objectify their learning success. Three-dimensional scans were taken and analyzed using a previously validated intraoral scanner to objectively assess the outcome.</p><p><strong>Results: </strong>The ex vivo cleft lip models are suitable for the training of students and experienced surgeons with varying levels of experience in cleft lip repair. Both models were rated as realistic in terms of tissue resemblance, surgical planning, and surgical management. In addition, the specialists rated the models as realistic overall. The models also provide students with several advantages, such as improved surgical skills and a better understanding of cleft surgery. Participants felt that the models should be made available not only to residents, but also to consultants and senior consultants and should be implicated in the dental curriculum.</p><p><strong>Conclusion: </strong>The ex vivo cleft lip models made of porcine snout discs are suitable for a wide range of users starting from students to experienced surgeons to train in cleft lip surgery. The great advantage of these models is that experienced surgeons can work with an inexpensive and readily available model to improve their skills and modify their techniques.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":"86"},"PeriodicalIF":2.4,"publicationDate":"2025-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12702147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145677438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lessening the erosive influence of electrolyte sports drinks on teeth using L-arginine and aqueous Miswak extract. 利用l -精氨酸和水萃取物减少电解质运动饮料对牙齿的侵蚀作用。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-29 DOI: 10.1186/s13005-025-00560-3
Hanaa Elgamily, Engie Safwat, Reham Sayed, Samah Mosbah, Ahmed Yossef

Objective: Excessive intake of electrolyte sports drinks (ESDs) among adolescents and athletes is associated with dental erosion due to their low pH, while their sugar content increases the risk of dental caries. This study aimed to evaluate and compare the protective effects of incorporating either L-arginine or Salvadora persica (Miswak) extract into an ESD on enamel surface properties.

Materials and methods: Extracted human premolars were randomly assigned to three groups (n = 6): (1) plain ESD, (2) ESD with 1% L-arginine (Arg-ESD), and (3) ESD with 10% Salvadora persica extract (Mis-ESD). Each specimen was immersed in its respective solution for 5 min daily over 7 days. Post-treatment assessments included enamel microhardness (VHN), surface roughness (Sa), colour change (ΔE), Ca/P ratio, and scanning electron microscopy (SEM) for surface morphology. A taste acceptability survey was conducted in adult volunteers. Statistical analysis used one-way ANOVA (α = 0.05). In addition, a small panel of adult volunteers (n = 20) evaluated the taste acceptability of the modified formulations after providing informed consent.

Results: Both Arg-ESD and Mis-ESD significantly increased enamel microhardness and reduced surface roughness compared to plain ESD (P < 0.01), with Mis-ESD showing the greatest improvements. Mis-ESD also enhanced colour stability (P < 0.001). SEM images confirmed preservation of enamel structure, particularly in Mis-ESD specimens. Taste testing indicated good palatability for both modified formulations.

Conclusion: Incorporating Salvadora persica extract into ESDs significantly improved enamel resistance to erosion and enhanced aesthetic properties. Miswak-enriched ESDs could serve as a preventive option for dental erosion.

Clinical relevance: Formulating ESDs with Salvadora persica may reduce their erosive potential while preserving taste acceptability, offering a novel, consumer-friendly strategy to protect enamel in high-risk populations.

目的:青少年和运动员过量摄入电解质运动饮料(ESDs)因其pH值低而与牙齿侵蚀有关,而其含糖量增加了龋齿的风险。本研究旨在评估和比较将l -精氨酸或木耳提取物加入到ESD中对牙釉质表面特性的保护作用。材料与方法:将提取的人前磨牙随机分为3组(n = 6):(1)普通ESD组,(2)1% l -精氨酸ESD组(Arg-ESD),(3) 10%木耳提取物ESD组(miss -ESD)。每个标本在各自的溶液中浸泡5分钟,持续7天。处理后的评估包括牙釉质显微硬度(VHN)、表面粗糙度(Sa)、颜色变化(ΔE)、Ca/P比和扫描电子显微镜(SEM)的表面形貌。对成年志愿者进行了味觉接受度调查。统计学分析采用单因素方差分析(α = 0.05)。此外,一小组成年志愿者(n = 20)在提供知情同意后评估了修改配方的口味可接受性。结果:与普通ESD相比,Arg-ESD和miss -ESD均显著提高了牙釉质的显微硬度,降低了表面粗糙度(P结论:将木耳提取物加入到ESD中可以显著提高牙釉质的抗侵蚀能力,增强了美观性。miswake富集的esd可以作为牙齿侵蚀的预防选择。临床意义:用胡桃木配制esd可以减少其侵蚀潜力,同时保持味道的可接受性,为保护高危人群的牙釉质提供了一种新颖的、消费者友好的策略。
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引用次数: 0
The effect of folic acid or multivitamin containing folic acid supplementation during pregnancy on enamel structure of deciduous teeth: an ultrastructural and microanalytical study. 妊娠期补充叶酸或含叶酸的多种维生素对乳牙釉质结构的影响:一项超微结构和显微分析研究。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-29 DOI: 10.1186/s13005-025-00564-z
Nermeen AbuBakr, Dina B E Farag, Marwa A El-Saeed, Dina M Elkady

Objectives: This work aimed to investigate the impact of folic acid or multivitamin containing folic acid supplementation during pregnancy on morphology and mineral content of enamel structure in deciduous teeth.

Materials and methods: 54 exfoliating deciduous upper central incisors were extracted from children between the ages of 6 and 8. Teeth were divided according to the maternal use of micronutrients into three groups (n = 18), group I: no use; group II: folic acid; and group III: multivitamin containing folic acid. Specimens' ultrastructure was examined by scanning electron microscope (SEM). Elemental analysis was done using energy-dispersive X-ray spectroscopy (EDX), then statistical evaluation was conducted.

Results: SEM analysis revealed a uniform enamel surface morphology, indicating a level of resistance to normal physiological enamel wear in groups II and III in contrast to group I. These findings were affirmed by EDX assessment where enamel surface revealed statistically significant higher values for calcium, and phosphorus in groups II and III relative to group I. Additionally, carbon content revealed statistically significant higher values in group I than those of groups II and III, suggesting more susceptibility of hydroxyapatite crystals to dissolution in group Ι.

Conclusion: Maternal micronutrients supplementation was linked with the preservation of enamel structure in primary teeth. This indicates enhanced enamel resistance to mineral loss during normal physiological dental wear. The findings of this preliminary study highlighted the importance of prenatal multivitamin supplementation as a strategy in preventive dentistry.

目的:探讨妊娠期补充叶酸或含多种维生素叶酸对乳牙牙釉质结构形态和矿物质含量的影响。材料与方法:选取6 ~ 8岁儿童54颗脱落的上中切牙。根据产妇牙齿微量营养素使用情况分为3组(n = 18),第一组:未使用;第二组:叶酸;第三组:含叶酸的复合维生素。用扫描电镜(SEM)观察样品的超微结构。采用能量色散x射线能谱(EDX)进行元素分析,并进行统计评价。结果:扫描电镜分析显示,牙釉质表面形态均匀,表明II组和III组比I组对正常生理牙釉质磨损有一定程度的抵抗力。EDX评估证实了这一发现,II组和III组牙釉质表面的钙、磷含量比I组高,具有统计学意义。此外,碳含量在I组比II组和III组高,具有统计学意义。提示Ι组羟基磷灰石晶体对溶解更敏感。结论:母体微量营养素的补充与乳牙釉质结构的保存有关。这表明在正常的牙齿生理磨损过程中,牙釉质对矿物质流失的抵抗力增强。这项初步研究的结果强调了产前补充多种维生素作为预防性牙科策略的重要性。
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引用次数: 0
Interobserver reliability in the 3D facial scan assessment of the outcome in dermal filler therapy. 三维面部扫描评估真皮填充治疗结果的观察者间可靠性。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-29 DOI: 10.1186/s13005-025-00562-1
Anna Vadasz, Mate Vlocsko, Tamas Tarjanyi, Ferenc Rarosi, Tamas Vereb, Anna Lili Zicsi-Liess, Laszlo Hegedus, Veronika Agnes Jancsik, Jozsef Piffko

Study design: We conducted a prospective cohort study comparing interobserver reliability of 2 different 3D scanning measurement methods following dermal filler therapy in oral cleft patients.

Objective of the study: The objective of the study was to compare the interobserver reliability of 2 different assessment methods of 3D facial scan data.

Methods: We studied 10 oral-cleft patients prospectively who underwent dermal filler therapy in the oral region by a single oral-surgeon using a modified injecting technique with 27 gauge 25 mm micro-cannula between 2021 and 2023. 3D facial scans were made before the treatment procedure and during follow-up visits and were used for analysis. The interbody fusion was scored on these 3D images using the 2 classification systems (Method 1, Method 2) by 3 experienced orthodontic specialists all of whom were blinded to clinical data and outcome.

Results: Of the 2 classifications included in the current study, all classifications had a high interobserver agreement.

Conclusion: The 2 assessment methods used in this study showed high interobserver reliability so we can conclude that, the applied methods may provide as a validation in the outcome of dermal filler therapy. However, we suggest that further refinements may be required to achieve a reliable and consistent assessment of 3D facial scan analysis after dermal filler therapy in oral cleft patients.

研究设计:我们进行了一项前瞻性队列研究,比较了两种不同的3D扫描测量方法在口腔腭裂患者真皮填充治疗后的观察者间可靠性。研究目的:本研究的目的是比较两种不同的三维面部扫描数据评估方法的观察者间信度。方法:我们前瞻性研究了10例口腔腭裂患者,这些患者在2021年至2023年期间由一名口腔外科医生使用改良的注射技术,使用27号25毫米微套管在口腔区域进行真皮填充治疗。在治疗前和随访期间进行3D面部扫描,并用于分析。3名经验丰富的正畸专家对临床数据和结果不知情,使用2种分类系统(方法1、方法2)对这些3D图像进行体间融合评分。结果:在本研究纳入的2种分类中,所有分类均具有较高的观察者间一致性。结论:本研究使用的两种评估方法具有较高的观察者间信度,因此我们可以得出结论,所采用的方法可以作为真皮填充治疗结果的验证方法。然而,我们建议可能需要进一步的改进,以实现可靠和一致的评估,在口腔腭裂患者真皮填充治疗后的3D面部扫描分析。
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引用次数: 0
A deep learning framework for automated dental segmentation and diagnostic report generation from cone-beam computed tomography. 一个深度学习框架,用于从锥形束计算机断层扫描中自动分割牙齿和生成诊断报告。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-28 DOI: 10.1186/s13005-025-00555-0
Wenbo Zhou, Dan Zhao, Bingyang Zhao, Miyi Shen, Xin Liu

Background: To develop a deep learning-based model that is capable of automatically segmenting teeth in cone-beam computed tomography (CBCT) images and generating auxiliary diagnostic reports.

Methods: A two-stage pipeline model comprising a segmentation module and a classification module was designed. The segmentation module integrates the 3D TransUNet model and fine-tuned nnU-Netv2 framework to predict tooth location and numbering. The classification module uses a 3D DenseNet169 model to assess tooth conditions and detect dental diseases. A total of 450 CBCT datasets were collected, preprocessed, and annotated with tooth contours, numbering, and disease status. The dataset was randomly split into training, validation, and test sets at a 3:1:1 ratio. The model's performance was then evaluated by using multiple quantitative metrics.

Results: The segmentation module achieved a Dice similarity coefficient (DSC) of 0.9409 and an average symmetric surface distance (ASSD) of 0.5011. The classification module, which is based on the 3D DenseNet169 model, achieved an accuracy of 0.9297 and an F1-score of 0.9252.

Conclusions: The two-stage pipeline model effectively integrates automated tooth segmentation and auxiliary diagnosis. The segmentation module demonstrates high accuracy, while the classification module exhibits strong diagnostic performance. The final output seamlessly combines segmentation and the diagnostic results, enabling the automated generation of structured auxiliary diagnostic reports with tooth numbering. By significantly enhancing the diagnostic efficiency, the proposed method offers substantial support for clinical decision-making in dentistry and holds great potential for real-world applications.

背景:开发一种基于深度学习的模型,该模型能够自动分割锥形束计算机断层扫描(CBCT)图像中的牙齿并生成辅助诊断报告。方法:设计了由分割模块和分类模块组成的两阶段管道模型。分割模块集成了3D TransUNet模型和微调的nnU-Netv2框架来预测牙齿的位置和编号。分类模块使用3D DenseNet169模型来评估牙齿状况并检测牙齿疾病。总共收集了450个CBCT数据集,进行了预处理,并对牙齿轮廓、编号和疾病状态进行了注释。数据集以3:1:1的比例随机分为训练集、验证集和测试集。然后使用多个定量指标对模型的性能进行评估。结果:该分割模块的Dice相似系数(DSC)为0.9409,平均对称表面距离(ASSD)为0.5011。基于3D DenseNet169模型的分类模块,准确率为0.9297,f1得分为0.9252。结论:两阶段管道模型有效地集成了自动牙齿分割和辅助诊断。分割模块具有较高的准确率,分类模块具有较强的诊断性能。最终输出将分割和诊断结果无缝地结合在一起,从而能够自动生成带有牙齿编号的结构化辅助诊断报告。该方法显著提高了诊断效率,为临床决策提供了有力的支持,在实际应用中具有很大的潜力。
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引用次数: 0
Three-dimensional soft tissue changes after simulated protrusion of upper and lower incisors in young adults: an experimental study. 青壮年上、下切牙模拟前突后三维软组织变化的实验研究。
IF 2.4 2区 医学 Q2 DENTISTRY, ORAL SURGERY & MEDICINE Pub Date : 2025-11-27 DOI: 10.1186/s13005-025-00561-2
Julia C Glöggler, To Mai Pham, Falko Schmidt, Stefan Repky, Bernd G Lapatki

Background: One component of facial aesthetics is a harmonic facial profile. Orthodontic treatment and/or orthognathic surgery can affect the facial profile by influencing the underlying hard-tissue structure. The aim of this study was to improve the prediction of treatment outcomes by evaluating 3D perioral frontal and buccal soft-tissue changes after protrusion of incisors in ten young adults.

Methods: The participants had neutral occlusion and physiologic incisor inclination. 3D-printed acrylic veneers with thicknesses of 1-4 mm were bonded to the labial surfaces of the upper and lower incisors. 3D face scans with and without veneers were taken to evaluate perioral soft tissue changes using 44 landmarks. Face scans were superimposed at the forehead. Soft-tissue changes were evaluated using linear mixed-effects models.

Results: Interrelations between simulated incisor protrusion and the resulting soft-tissue changes were statistically highly significant (p < 0.005) and nearly linear. Simulated isolated upper incisor protrusion caused greatest forward positioning of the labrale superius convex [LS-con] landmark-by 0.65 mm per millimetre of veneer thickness. Lower lip displacement at the labrale inferius convex [LI-con] landmark was greatest when both upper and lower incisors were protruded (0.76 mm/mm). The vertical lip displacement rate for simulated upper and lower incisor protrusion was 0.12 mm/mm upward positioning of LS-con and 0.66 mm/mm downward positioning of LI-con. Mixed-effects models revealed that a 1-mm increase in initial lip thickness at the labrale superius reduces soft-tissue displacement by about 8% of the simulated tooth movement.

Conclusions: Anterior positioning of incisors leads to predictable, direction-specific changes in perioral soft tissues. The magnitude and pattern of soft-tissue responses vary with the combination of upper and lower incisor movement and individual lip thickness. These findings may support clinical planning in orthodontic and/or orthognathic treatments.

背景:面部美学的一个组成部分是和谐的面部轮廓。正畸治疗和/或正颌手术可以通过影响潜在的硬组织结构来影响面部轮廓。本研究的目的是通过评估10名年轻人门牙突出后的三维口腔周围、额部和颊部软组织变化来提高治疗结果的预测。方法:中立咬合,生理性切牙倾斜。将厚度为1-4毫米的3d打印丙烯酸贴面粘合在上、下门牙的唇面。采用带贴面和不带贴面的3D面部扫描,使用44个地标来评估口腔周围软组织的变化。面部扫描叠加在前额。采用线性混合效应模型评估软组织变化。结果:模拟切牙前突与软组织变化之间的相互关系在统计学上具有高度显著性(p)。结论:切牙前位可导致可预测的、方向特异性的口腔周围软组织变化。软组织反应的大小和模式随上下切牙运动和个体唇厚的组合而变化。这些发现可能支持正畸和/或正颌治疗的临床规划。
{"title":"Three-dimensional soft tissue changes after simulated protrusion of upper and lower incisors in young adults: an experimental study.","authors":"Julia C Glöggler, To Mai Pham, Falko Schmidt, Stefan Repky, Bernd G Lapatki","doi":"10.1186/s13005-025-00561-2","DOIUrl":"10.1186/s13005-025-00561-2","url":null,"abstract":"<p><strong>Background: </strong>One component of facial aesthetics is a harmonic facial profile. Orthodontic treatment and/or orthognathic surgery can affect the facial profile by influencing the underlying hard-tissue structure. The aim of this study was to improve the prediction of treatment outcomes by evaluating 3D perioral frontal and buccal soft-tissue changes after protrusion of incisors in ten young adults.</p><p><strong>Methods: </strong>The participants had neutral occlusion and physiologic incisor inclination. 3D-printed acrylic veneers with thicknesses of 1-4 mm were bonded to the labial surfaces of the upper and lower incisors. 3D face scans with and without veneers were taken to evaluate perioral soft tissue changes using 44 landmarks. Face scans were superimposed at the forehead. Soft-tissue changes were evaluated using linear mixed-effects models.</p><p><strong>Results: </strong>Interrelations between simulated incisor protrusion and the resulting soft-tissue changes were statistically highly significant (p < 0.005) and nearly linear. Simulated isolated upper incisor protrusion caused greatest forward positioning of the labrale superius convex [LS-con] landmark-by 0.65 mm per millimetre of veneer thickness. Lower lip displacement at the labrale inferius convex [LI-con] landmark was greatest when both upper and lower incisors were protruded (0.76 mm/mm). The vertical lip displacement rate for simulated upper and lower incisor protrusion was 0.12 mm/mm upward positioning of LS-con and 0.66 mm/mm downward positioning of LI-con. Mixed-effects models revealed that a 1-mm increase in initial lip thickness at the labrale superius reduces soft-tissue displacement by about 8% of the simulated tooth movement.</p><p><strong>Conclusions: </strong>Anterior positioning of incisors leads to predictable, direction-specific changes in perioral soft tissues. The magnitude and pattern of soft-tissue responses vary with the combination of upper and lower incisor movement and individual lip thickness. These findings may support clinical planning in orthodontic and/or orthognathic treatments.</p>","PeriodicalId":12994,"journal":{"name":"Head & Face Medicine","volume":" ","pages":"8"},"PeriodicalIF":2.4,"publicationDate":"2025-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12849403/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145632708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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Head & Face Medicine
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