Pub Date : 2024-06-01DOI: 10.1097/js9.0000000000001761
{"title":"A decision tree model to help treatment decision-making for severe spontaneous intracerebral hemorrhage: Erratum","authors":"","doi":"10.1097/js9.0000000000001761","DOIUrl":"https://doi.org/10.1097/js9.0000000000001761","url":null,"abstract":"","PeriodicalId":12,"journal":{"name":"ACS Chemical Health & Safety","volume":"36 143","pages":""},"PeriodicalIF":15.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141389687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1097/js9.0000000000001760
{"title":"A multicenter case–controlled study on laparoscopic hepatectomy versus microwave ablation as first-line therapy for 3–5 cm hepatocellular carcinoma in patients aged 60 and older: Erratum","authors":"","doi":"10.1097/js9.0000000000001760","DOIUrl":"https://doi.org/10.1097/js9.0000000000001760","url":null,"abstract":"","PeriodicalId":12,"journal":{"name":"ACS Chemical Health & Safety","volume":"32 3","pages":""},"PeriodicalIF":15.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141390232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1097/js9.0000000000001759
{"title":"Successful robotic kidney transplantation for surgeons with no experience in minimally invasive surgery: a single institution experience: Erratum","authors":"","doi":"10.1097/js9.0000000000001759","DOIUrl":"https://doi.org/10.1097/js9.0000000000001759","url":null,"abstract":"","PeriodicalId":12,"journal":{"name":"ACS Chemical Health & Safety","volume":"10 3","pages":""},"PeriodicalIF":15.3,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141409527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.1016/j.jaad.2024.05.069
D. Elston
{"title":"Book Review: Cosmetic procedures in skin of color","authors":"D. Elston","doi":"10.1016/j.jaad.2024.05.069","DOIUrl":"https://doi.org/10.1016/j.jaad.2024.05.069","url":null,"abstract":"","PeriodicalId":12,"journal":{"name":"ACS Chemical Health & Safety","volume":"9 4","pages":""},"PeriodicalIF":13.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141411055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-15DOI: 10.1097/js9.0000000000001609
Rekha Khandia, Pankaj Gurjar, Priyanka, Victoria Romashchenko, Sami A. Al-HUSSAIN, Magdi E. A. Zaki
Neurodegeneration refers to the gradual loss of neurons and extensive changes occur in glial cells like tau inclusions in astrocytes and oligodendrocytes, α-synuclein inclusions in oligodendrocytes and SOD1 aggregates in astrocytes along with deterioration in the motor, cognition, learning, and behaviour. Common neurodegenerative disorders are Alzheimer’s Disease (AD), Parkinson’s Disease (PD), Amyotrophic Lateral Sclerosis (ALS), Huntington’s disease (HD), Spinocerebellar Ataxia (SCAs), and Supranuclear palsy are some common one. There is a lack of effective treatment for neurodegenerative diseases, and scientists are putting their efforts into developing therapies against them. Stem cell therapy has emerged as a hope for neurodegenerative disorders since it is not only the damaged neurons that might be replaced, but other neuromodulators and neuroprotectors are secreted. Stem cell terminal differentiation before implantation ensures the implantation of correct cells and molecular markers like carbonic anhydrase II, CNPase (2′,3′-cyclic nucleotide 3′-phosphohydrolase), myelin basic protein (MBP), and myelin oligodendrocyte glycoprotein (MOG) elucidate the differentiation. Secretion of various growth factors like epidermal growth factor (EGF), keratinocyte growth factor (KGF), vascular endothelial growth factor-α (VEGF-α), transforming growth factor (TGF) and macrophage inflammatory protein (MIP) supports cell survival, cell proliferation, blood vessel formation, axon regeneration, and neuroglial functional connection formation at the site of degeneration. Adverse effects of stem cell therapy, like teratogenicity and differentiation in different cells other than the desired one under the influence of microenvironment, are a few key concerns. Post-transplantation improved synaptic plasticity, apoptosis inhibition, and reduction in tau-phosphorylation and Amyloid beta (Aβ) production has been observed in Alzheimer’s patients.A large number of experimental, preclinical, and clinical studies have been conducted, and encouraging results have been obtained. The present review exhaustively discusses various kinds of stem cells, their usage in treating neurodegenerative disorders, limitations and challenges, and ethical issues related to stem cell therapy.
神经退行性变是指神经元逐渐丧失,神经胶质细胞发生广泛变化,如星形胶质细胞和少突胶质细胞中的 tau 包涵体、少突胶质细胞中的α-突触核蛋白包涵体和星形胶质细胞中的 SOD1 聚集体,同时运动、认知、学习和行为也发生恶化。常见的神经退行性疾病有阿尔茨海默病(AD)、帕金森病(PD)、肌萎缩侧索硬化症(ALS)、亨廷顿病(HD)、脊髓小脑共济失调(SCA)和核上性麻痹等。神经退行性疾病缺乏有效的治疗方法,科学家们正在努力开发针对这些疾病的疗法。干细胞疗法已成为治疗神经退行性疾病的希望,因为它不仅可以替代受损的神经元,还能分泌其他神经调节剂和神经保护剂。干细胞植入前的终末分化可确保植入正确的细胞,而碳酸酐酶 II、CNPase(2′,3′-环核苷酸 3′-磷酸水解酶)、髓鞘碱性蛋白(MBP)和髓鞘少突胶质细胞糖蛋白(MOG)等分子标记则可阐明分化过程。表皮生长因子(EGF)、角质细胞生长因子(KGF)、血管内皮生长因子-α(VEGF-α)、转化生长因子(TGF)和巨噬细胞炎症蛋白(MIP)等各种生长因子的分泌支持细胞存活、细胞增殖、血管形成、轴突再生和变性部位神经胶质功能连接的形成。干细胞疗法的不良反应,如致畸性和在微环境影响下分化为所需细胞以外的不同细胞,是人们关注的几个关键问题。移植后,阿尔茨海默病患者的突触可塑性得到改善,细胞凋亡受到抑制,tau磷酸化和淀粉样β(Aβ)生成减少。本综述详尽讨论了各种干细胞、其在治疗神经退行性疾病中的应用、局限性和挑战,以及与干细胞疗法相关的伦理问题。
{"title":"Recent advances in stem cells therapy: efficacy, ethics, safety concerns and future directions focusing on neurodegenerative disorders- a review","authors":"Rekha Khandia, Pankaj Gurjar, Priyanka, Victoria Romashchenko, Sami A. Al-HUSSAIN, Magdi E. A. Zaki","doi":"10.1097/js9.0000000000001609","DOIUrl":"https://doi.org/10.1097/js9.0000000000001609","url":null,"abstract":"Neurodegeneration refers to the gradual loss of neurons and extensive changes occur in glial cells like tau inclusions in astrocytes and oligodendrocytes, α-synuclein inclusions in oligodendrocytes and SOD1 aggregates in astrocytes along with deterioration in the motor, cognition, learning, and behaviour. Common neurodegenerative disorders are Alzheimer’s Disease (AD), Parkinson’s Disease (PD), Amyotrophic Lateral Sclerosis (ALS), Huntington’s disease (HD), Spinocerebellar Ataxia (SCAs), and Supranuclear palsy are some common one. There is a lack of effective treatment for neurodegenerative diseases, and scientists are putting their efforts into developing therapies against them. Stem cell therapy has emerged as a hope for neurodegenerative disorders since it is not only the damaged neurons that might be replaced, but other neuromodulators and neuroprotectors are secreted. Stem cell terminal differentiation before implantation ensures the implantation of correct cells and molecular markers like carbonic anhydrase II, CNPase (2′,3′-cyclic nucleotide 3′-phosphohydrolase), myelin basic protein (MBP), and myelin oligodendrocyte glycoprotein (MOG) elucidate the differentiation. Secretion of various growth factors like epidermal growth factor (EGF), keratinocyte growth factor (KGF), vascular endothelial growth factor-α (VEGF-α), transforming growth factor (TGF) and macrophage inflammatory protein (MIP) supports cell survival, cell proliferation, blood vessel formation, axon regeneration, and neuroglial functional connection formation at the site of degeneration. Adverse effects of stem cell therapy, like teratogenicity and differentiation in different cells other than the desired one under the influence of microenvironment, are a few key concerns. Post-transplantation improved synaptic plasticity, apoptosis inhibition, and reduction in tau-phosphorylation and Amyloid beta (Aβ) production has been observed in Alzheimer’s patients.A large number of experimental, preclinical, and clinical studies have been conducted, and encouraging results have been obtained. The present review exhaustively discusses various kinds of stem cells, their usage in treating neurodegenerative disorders, limitations and challenges, and ethical issues related to stem cell therapy.","PeriodicalId":12,"journal":{"name":"ACS Chemical Health & Safety","volume":"74 6","pages":""},"PeriodicalIF":15.3,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140973869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-15DOI: 10.1158/0008-5472.can-24-1256
M. Hirst
{"title":"Connie Eaves, PhD, FAACR: In Memoriam (1944–2024)","authors":"M. Hirst","doi":"10.1158/0008-5472.can-24-1256","DOIUrl":"https://doi.org/10.1158/0008-5472.can-24-1256","url":null,"abstract":"","PeriodicalId":12,"journal":{"name":"ACS Chemical Health & Safety","volume":"49 3","pages":""},"PeriodicalIF":11.2,"publicationDate":"2024-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140972711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-07DOI: 10.1108/aci-12-2023-0195
Atef Gharbi
PurposeThe present paper aims to address challenges associated with path planning and obstacle avoidance in mobile robotics. It introduces a pioneering solution called the Bi-directional Adaptive Enhanced A* (BAEA*) algorithm, which uses a new bidirectional search strategy. This approach facilitates simultaneous exploration from both the starting and target nodes and improves the efficiency and effectiveness of the algorithm in navigation environments. By using the heuristic knowledge A*, the algorithm avoids unproductive blind exploration, helps to obtain more efficient data for identifying optimal solutions. The simulation results demonstrate the superior performance of the BAEA* algorithm in achieving rapid convergence towards an optimal action strategy compared to existing methods.Design/methodology/approachThe paper adopts a careful design focusing on the development and evaluation of the BAEA* for mobile robot path planning, based on the reference [18]. The algorithm has remarkable adaptability to dynamically changing environments and ensures robust navigation in the context of environmental changes. Its scale further enhances its applicability in large and complex environments, which means it has flexibility for various practical applications. The rigorous evaluation of our proposed BAEA* algorithm with the Bidirectional adaptive A* (BAA*) algorithm [18] in five different environments demonstrates the superiority of the BAEA* algorithm. The BAEA* algorithm consistently outperforms BAA*, demonstrating its ability to plan shorter and more stable paths and achieve higher success rates in all environments.FindingsThe paper adopts a careful design focusing on the development and evaluation of the BAEA* for mobile robot path planning, based on the reference [18]. The algorithm has remarkable adaptability to dynamically changing environments and ensures robust navigation in the context of environmental changes. Its scale further enhances its applicability in large and complex environments, which means it has flexibility for various practical applications. The rigorous evaluation of our proposed BAEA* algorithm with the Bi-directional adaptive A* (BAA*) algorithm [18] in five different environments demonstrates the superiority of the BAEA* algorithm.Research limitations/implicationsThe rigorous evaluation of our proposed BAEA* algorithm with the BAA* algorithm [18] in five different environments demonstrates the superiority of the BAEA* algorithm. The BAEA* algorithm consistently outperforms BAA*, demonstrating its ability to plan shorter and more stable paths and achieve higher success rates in all environments.Originality/valueThe originality of this paper lies in the introduction of the bidirectional adaptive enhancing A* algorithm (BAEA*) as a novel solution for path planning for mobile robots. This algorithm is characterized by its unique characteristics that distinguish it from others in this field. First, BAEA* uses a unique bidirectional s
{"title":"Bi-directional adaptive enhanced A* algorithm for mobile robot navigation","authors":"Atef Gharbi","doi":"10.1108/aci-12-2023-0195","DOIUrl":"https://doi.org/10.1108/aci-12-2023-0195","url":null,"abstract":"PurposeThe present paper aims to address challenges associated with path planning and obstacle avoidance in mobile robotics. It introduces a pioneering solution called the Bi-directional Adaptive Enhanced A* (BAEA*) algorithm, which uses a new bidirectional search strategy. This approach facilitates simultaneous exploration from both the starting and target nodes and improves the efficiency and effectiveness of the algorithm in navigation environments. By using the heuristic knowledge A*, the algorithm avoids unproductive blind exploration, helps to obtain more efficient data for identifying optimal solutions. The simulation results demonstrate the superior performance of the BAEA* algorithm in achieving rapid convergence towards an optimal action strategy compared to existing methods.Design/methodology/approachThe paper adopts a careful design focusing on the development and evaluation of the BAEA* for mobile robot path planning, based on the reference [18]. The algorithm has remarkable adaptability to dynamically changing environments and ensures robust navigation in the context of environmental changes. Its scale further enhances its applicability in large and complex environments, which means it has flexibility for various practical applications. The rigorous evaluation of our proposed BAEA* algorithm with the Bidirectional adaptive A* (BAA*) algorithm [18] in five different environments demonstrates the superiority of the BAEA* algorithm. The BAEA* algorithm consistently outperforms BAA*, demonstrating its ability to plan shorter and more stable paths and achieve higher success rates in all environments.FindingsThe paper adopts a careful design focusing on the development and evaluation of the BAEA* for mobile robot path planning, based on the reference [18]. The algorithm has remarkable adaptability to dynamically changing environments and ensures robust navigation in the context of environmental changes. Its scale further enhances its applicability in large and complex environments, which means it has flexibility for various practical applications. The rigorous evaluation of our proposed BAEA* algorithm with the Bi-directional adaptive A* (BAA*) algorithm [18] in five different environments demonstrates the superiority of the BAEA* algorithm.Research limitations/implicationsThe rigorous evaluation of our proposed BAEA* algorithm with the BAA* algorithm [18] in five different environments demonstrates the superiority of the BAEA* algorithm. The BAEA* algorithm consistently outperforms BAA*, demonstrating its ability to plan shorter and more stable paths and achieve higher success rates in all environments.Originality/valueThe originality of this paper lies in the introduction of the bidirectional adaptive enhancing A* algorithm (BAEA*) as a novel solution for path planning for mobile robots. This algorithm is characterized by its unique characteristics that distinguish it from others in this field. First, BAEA* uses a unique bidirectional s","PeriodicalId":12,"journal":{"name":"ACS Chemical Health & Safety","volume":"83 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141002485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-06DOI: 10.1021/acs.chas.4c00006
Claudia Cirillo, Mariagrazia Iuliano, Davide Scarpa, Luca Gallucci, Claudia Florio, Gaetano Maffei, Andrea Loi, Maria Sarno
The focus on the leather market has recently been on the rise due to the global increase in demand for leather products, driven by rising disposable income levels and improving standards of living among the expanding middle-class population. To enhance the performance of the final leather product, we have employed nanoparticles (NPs) across various stages of leather manufacturing. Specifically, in the finishing process─the ultimate stage of leather production─numerous studies have underscored the significance of Ag, TiO2, and SiO2 NPs in significantly enhancing various characteristics of leather. On the other hand, the rapid growth in the application of NPs to leather finishing, and more in general in the leather industry, has occurred concomitantly with increased attention toward potential risks associated with their usage in biological systems and ecosystems. Given these considerations, the objective of this critical review is to provide a detailed and thorough analysis of the factors influencing the toxicity and cytotoxicity of nanoparticles commonly adopted in the leather finishing stage, with particular emphasis on Ag, TiO2, and SiO2 NPs, along with their effects on the safety and health of workers. Moreover, the following study aims to identify necessary precautions and safety measures that the leather industry should implement when handling nanoparticles during the finishing stage.
{"title":"Nanoparticle Usage in Leather Processing: Worker Safety and Health","authors":"Claudia Cirillo, Mariagrazia Iuliano, Davide Scarpa, Luca Gallucci, Claudia Florio, Gaetano Maffei, Andrea Loi, Maria Sarno","doi":"10.1021/acs.chas.4c00006","DOIUrl":"https://doi.org/10.1021/acs.chas.4c00006","url":null,"abstract":"The focus on the leather market has recently been on the rise due to the global increase in demand for leather products, driven by rising disposable income levels and improving standards of living among the expanding middle-class population. To enhance the performance of the final leather product, we have employed nanoparticles (NPs) across various stages of leather manufacturing. Specifically, in the finishing process─the ultimate stage of leather production─numerous studies have underscored the significance of Ag, TiO<sub>2</sub>, and SiO<sub>2</sub> NPs in significantly enhancing various characteristics of leather. On the other hand, the rapid growth in the application of NPs to leather finishing, and more in general in the leather industry, has occurred concomitantly with increased attention toward potential risks associated with their usage in biological systems and ecosystems. Given these considerations, the objective of this critical review is to provide a detailed and thorough analysis of the factors influencing the toxicity and cytotoxicity of nanoparticles commonly adopted in the leather finishing stage, with particular emphasis on Ag, TiO<sub>2,</sub> and SiO<sub>2</sub> NPs, along with their effects on the safety and health of workers. Moreover, the following study aims to identify necessary precautions and safety measures that the leather industry should implement when handling nanoparticles during the finishing stage.","PeriodicalId":12,"journal":{"name":"ACS Chemical Health & Safety","volume":"16 1","pages":""},"PeriodicalIF":0.73,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140886033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-03DOI: 10.1097/js9.0000000000001548
Yawen He, Zhiyang Jiang, Yonghua Zhang
{"title":"A commentary on “The value of cholinesterase inhibitors for improving neuropsychiatric and functional assessment scores in patients with alzheimer disease: a systematic review and meta-analysis of on placebo-controlled RCTs”","authors":"Yawen He, Zhiyang Jiang, Yonghua Zhang","doi":"10.1097/js9.0000000000001548","DOIUrl":"https://doi.org/10.1097/js9.0000000000001548","url":null,"abstract":"","PeriodicalId":12,"journal":{"name":"ACS Chemical Health & Safety","volume":"35 2","pages":""},"PeriodicalIF":15.3,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141014936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-03DOI: 10.1097/js9.0000000000001520
Tingfen Han, Shuai Liu
{"title":"A commentary on “Timing of restoration of bowel continuity after decompressing stoma, in left-sided obstructive colon cancer: a nationwide retrospective cohort”","authors":"Tingfen Han, Shuai Liu","doi":"10.1097/js9.0000000000001520","DOIUrl":"https://doi.org/10.1097/js9.0000000000001520","url":null,"abstract":"","PeriodicalId":12,"journal":{"name":"ACS Chemical Health & Safety","volume":"16 S15","pages":""},"PeriodicalIF":15.3,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141016627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}