Pub Date : 2015-09-01DOI: 10.1097/01.XHA.0000471345.69722.b4
R. Inci, Perihan Öztürk, Kemal Özyurt, S. Bakarış, M. Inci
Idiopathic scrotal calcinosis is a benign condition characterized by the extensive slow-growing nodules over the scrotal skin. The disease is of unclear etiology and is of importance due to the disfigurement. Management is mostly surgical, with removal of the entire nodules, and the recurrence rate is high. We recently encountered a patient with chronic pancreatitis with incidentally detected scrotal calcinosis. We report the same here, along with the possible etiological mechanisms of this uncommon condition.
{"title":"Idiopathic scrotal calcinosis","authors":"R. Inci, Perihan Öztürk, Kemal Özyurt, S. Bakarış, M. Inci","doi":"10.1097/01.XHA.0000471345.69722.b4","DOIUrl":"https://doi.org/10.1097/01.XHA.0000471345.69722.b4","url":null,"abstract":"Idiopathic scrotal calcinosis is a benign condition characterized by the extensive slow-growing nodules over the scrotal skin. The disease is of unclear etiology and is of importance due to the disfigurement. Management is mostly surgical, with removal of the entire nodules, and the recurrence rate is high. We recently encountered a patient with chronic pancreatitis with incidentally detected scrotal calcinosis. We report the same here, along with the possible etiological mechanisms of this uncommon condition.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"25 1","pages":"58–60"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78535144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-09-01DOI: 10.1097/01.XHA.0000470182.71509.1b
Y. Elkhiat, A. Zedan, Mona Mostafa, A. Elhalwagi, Sara Alhosini
PurposeThe aim of this study was to evaluate sexual desire in a sample of married Egyptian women with polycystic ovarian syndrome (PCOS). Patients and methodsThis study was carried out on 85 married Egyptian women with PCOS and 63 normal married women (the control group) recruited from the gynecology and obstetrics clinic in Kasr El-Aini Hospital, Cairo University. Every case was subjected to full medical history, full sexual history, general and local examinations, and investigated for serum levels of luteinizing hormone, follicle-stimulating hormone, and testosterone. Pelvic ultrasound was performed and BMI was calculated. Each case was interviewed using a structured interview to answer the translated Arabic version of Female Sexual Desire Questionnaire (FSDQ) developed by Goldhammer and McCabe (2011). ResultsTotal FSDQ score showed significantly higher level in the control group compared with the PCOS group (P<0.001). Except for the solitary desire score, which was higher in the PCOS group than in the control group (P=0.02), all other domains of the FSDQ – namely, dyadic desire, resistance, positive relationship, concern, and sexual self-image – exhibited statistically significantly higher level in the control group ((P<0.001) than in the PCOS group. Among PCOS women, there was significantly higher FSDQ score among women without androgenic alopecia (P=0.02) and with normal testosterone level (P=0.04). ConclusionPCOS had a negative impact on female sexual desire. Although PCOS patients suffered from hyperandrogenism, they experienced decreased sexual desire, lacked the responsive sexual desire, and were less satisfied with the relationship with their partner. They were less confident with their bodies and experienced distress in relation to their sexual desire level. The presence of higher level of testosterone or androgenic alopecia in PCOS women is associated with reduced sexual desire.
{"title":"Sexual desire in a sample of married Egyptian women with polycystic ovarian syndrome","authors":"Y. Elkhiat, A. Zedan, Mona Mostafa, A. Elhalwagi, Sara Alhosini","doi":"10.1097/01.XHA.0000470182.71509.1b","DOIUrl":"https://doi.org/10.1097/01.XHA.0000470182.71509.1b","url":null,"abstract":"PurposeThe aim of this study was to evaluate sexual desire in a sample of married Egyptian women with polycystic ovarian syndrome (PCOS). Patients and methodsThis study was carried out on 85 married Egyptian women with PCOS and 63 normal married women (the control group) recruited from the gynecology and obstetrics clinic in Kasr El-Aini Hospital, Cairo University. Every case was subjected to full medical history, full sexual history, general and local examinations, and investigated for serum levels of luteinizing hormone, follicle-stimulating hormone, and testosterone. Pelvic ultrasound was performed and BMI was calculated. Each case was interviewed using a structured interview to answer the translated Arabic version of Female Sexual Desire Questionnaire (FSDQ) developed by Goldhammer and McCabe (2011). ResultsTotal FSDQ score showed significantly higher level in the control group compared with the PCOS group (P<0.001). Except for the solitary desire score, which was higher in the PCOS group than in the control group (P=0.02), all other domains of the FSDQ – namely, dyadic desire, resistance, positive relationship, concern, and sexual self-image – exhibited statistically significantly higher level in the control group ((P<0.001) than in the PCOS group. Among PCOS women, there was significantly higher FSDQ score among women without androgenic alopecia (P=0.02) and with normal testosterone level (P=0.04). ConclusionPCOS had a negative impact on female sexual desire. Although PCOS patients suffered from hyperandrogenism, they experienced decreased sexual desire, lacked the responsive sexual desire, and were less satisfied with the relationship with their partner. They were less confident with their bodies and experienced distress in relation to their sexual desire level. The presence of higher level of testosterone or androgenic alopecia in PCOS women is associated with reduced sexual desire.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"12 1","pages":"49–57"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77321359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-09-01DOI: 10.1097/01.XHA.0000469536.57747.e7
O. Shaeer, Kamal Sheer
PurposeThe Global Online Sexuality Survey (GOSS) is a world-wide epidemiologic study of sexuality. It was first launched in the Middle East in 2010 and then in the USA in 2011. The current report investigates homosexual orientation and practice. Patients and methodsGOSS was randomly deployed to English-speaking male web surfers in the USA through advertising on Facebook, regardless of surfing preferences. Online surveying provided a confidential and nonconfrontational environment. ResultsAn overall 27.8% reported sexual desire toward the same sex (male) in varying degrees, of whom 37.5% reported sexual encounters with males (practicing homosexuals; 10.3% of the total sample), mostly in the form of external stimulation, less commonly as anal receptive practice and then as anal insertive practice, in different combinations; 85.3% were egosyntonic and 14.7% were egodystonic; 62.5% of those reporting homosexual desire never had sexual contact with males (nonpracticing/suppressed homosexuals; 17.5% of total participants). Classified as per the Kinsey scale (#2513; #2513), 18.1% reported various grades of homosexual orientation. ConclusionThis is – to our knowledge – the first online survey to address the prevalence of homosexual orientation and practice in the USA, using several investigation methods, discriminating desire from practice, egosyntonic homosexuality from egodystonic, and investigating the pattern of homosexual activity. It is also the first investigation of the relationship between child abuse and homosexuality.
{"title":"The Global Online Sexuality Survey: The United States of America in 2011: homosexuality among English-speaking men","authors":"O. Shaeer, Kamal Sheer","doi":"10.1097/01.XHA.0000469536.57747.e7","DOIUrl":"https://doi.org/10.1097/01.XHA.0000469536.57747.e7","url":null,"abstract":"PurposeThe Global Online Sexuality Survey (GOSS) is a world-wide epidemiologic study of sexuality. It was first launched in the Middle East in 2010 and then in the USA in 2011. The current report investigates homosexual orientation and practice. Patients and methodsGOSS was randomly deployed to English-speaking male web surfers in the USA through advertising on Facebook, regardless of surfing preferences. Online surveying provided a confidential and nonconfrontational environment. ResultsAn overall 27.8% reported sexual desire toward the same sex (male) in varying degrees, of whom 37.5% reported sexual encounters with males (practicing homosexuals; 10.3% of the total sample), mostly in the form of external stimulation, less commonly as anal receptive practice and then as anal insertive practice, in different combinations; 85.3% were egosyntonic and 14.7% were egodystonic; 62.5% of those reporting homosexual desire never had sexual contact with males (nonpracticing/suppressed homosexuals; 17.5% of total participants). Classified as per the Kinsey scale (#2513; #2513), 18.1% reported various grades of homosexual orientation. ConclusionThis is – to our knowledge – the first online survey to address the prevalence of homosexual orientation and practice in the USA, using several investigation methods, discriminating desire from practice, egosyntonic homosexuality from egodystonic, and investigating the pattern of homosexual activity. It is also the first investigation of the relationship between child abuse and homosexuality.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"45 1 1","pages":"45–48"},"PeriodicalIF":0.0,"publicationDate":"2015-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82722930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-06-01DOI: 10.1097/01.XHA.0000464891.95396.23
T. Mostafa, Rashad M. Mostafa, M. Hassan, Y. Nasrallah, W. S. Salman, M. Taymour
Menopause is a natural critical period of every woman’s life that is usually associated with physical, behavioral, and psychological changes. This review article aimed to highlight female sexual changes that could take place during such period. A review of the already published articles in this context was carried out using PubMed, Medical Subject Headings (MeSH) database, Excerpta Medica dataBASE, Cochrane Central Register of Controlled Trials, Google Scholar, and Scopus engine until March 2015. The following keywords were used to assess exposure, outcome, and estimates for concerned associations: menopause; sex; female sexual dysfunction; libido; behavior; menopause; postmenopause, humans, and aging. Most studies on this subject correlated hormonal changes during this period with significantly decreased domains of female sexual functions, such as desire, arousal, satisfaction, orgasm, lubrication, and experiencing coital pains. Fortunately, many scientists have taken efforts to alleviate these disorders using emerging treatment methods, topical remedies, and suggested alternative medicament. Significant decreases in female sexual domains are experienced during the postmenopausal period. However, proper counseling, explanations, specific remedies and partner guidance are helpful in overcoming female sexual changes during this period.
{"title":"Female sexual dysfunction among menopausal women","authors":"T. Mostafa, Rashad M. Mostafa, M. Hassan, Y. Nasrallah, W. S. Salman, M. Taymour","doi":"10.1097/01.XHA.0000464891.95396.23","DOIUrl":"https://doi.org/10.1097/01.XHA.0000464891.95396.23","url":null,"abstract":"Menopause is a natural critical period of every woman’s life that is usually associated with physical, behavioral, and psychological changes. This review article aimed to highlight female sexual changes that could take place during such period. A review of the already published articles in this context was carried out using PubMed, Medical Subject Headings (MeSH) database, Excerpta Medica dataBASE, Cochrane Central Register of Controlled Trials, Google Scholar, and Scopus engine until March 2015. The following keywords were used to assess exposure, outcome, and estimates for concerned associations: menopause; sex; female sexual dysfunction; libido; behavior; menopause; postmenopause, humans, and aging. Most studies on this subject correlated hormonal changes during this period with significantly decreased domains of female sexual functions, such as desire, arousal, satisfaction, orgasm, lubrication, and experiencing coital pains. Fortunately, many scientists have taken efforts to alleviate these disorders using emerging treatment methods, topical remedies, and suggested alternative medicament. Significant decreases in female sexual domains are experienced during the postmenopausal period. However, proper counseling, explanations, specific remedies and partner guidance are helpful in overcoming female sexual changes during this period.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"37 1","pages":"23–27"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72668329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-06-01DOI: 10.1097/01.XHA.0000466352.34893.52
K. H. Kumar, Sandeep Kumar
Neurofibromatosis type 1 is the most common phakomatoses and is inherited as an autosomal-dominant disorder. The characteristic feature of the disease is the presence of multiple cutaneous neurofibromas over the trunk and limbs. Penile neurofibromas are extremely rare and simultaneous occurrence of neurofibromas in the breasts has not been reported previously. We recently encountered a young male patient with an unusual combination of penile, bilateral breast, and multiple intraosseous neurofibromas. We report the case for its uncommon occurrence and to highlight the restricted distribution of the neurofibromas in erotic organs such as the breasts and penis.
{"title":"Neurofibroma erotica in a young male","authors":"K. H. Kumar, Sandeep Kumar","doi":"10.1097/01.XHA.0000466352.34893.52","DOIUrl":"https://doi.org/10.1097/01.XHA.0000466352.34893.52","url":null,"abstract":"Neurofibromatosis type 1 is the most common phakomatoses and is inherited as an autosomal-dominant disorder. The characteristic feature of the disease is the presence of multiple cutaneous neurofibromas over the trunk and limbs. Penile neurofibromas are extremely rare and simultaneous occurrence of neurofibromas in the breasts has not been reported previously. We recently encountered a young male patient with an unusual combination of penile, bilateral breast, and multiple intraosseous neurofibromas. We report the case for its uncommon occurrence and to highlight the restricted distribution of the neurofibromas in erotic organs such as the breasts and penis.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"9 1","pages":"33–35"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78479038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-06-01DOI: 10.1097/01.XHA.0000466753.24941.2a
A. Hassanin, Heba G. El-Shirbini
PurposeThe aim of the study was to evaluate the effect of smoking on retention of excess cytoplasm by spermatozoa in infertile men. Patients and methodsTwo groups of idiopathic infertile men, group 1 (20 smokers) and group 2 (20 nonsmokers), were included in the study. The cytoplasmic droplet (CD)/defective CD was evaluated as an independent variable in Papanicolaou-stained seminal smears for each participant, in addition to the standard semen parameter. CD greater than one-third the sperm head size was considered defective [excess residual cytoplasm (ERC)]. ResultsDefective CD (ERC), total head defects, total tail defects, and total abnormal forms were significantly higher in the smoker group. Significant positive correlation was found between defective CD (ERC) and both the number of smoked cigarettes/day and the duration of smoking. ConclusionRetention of excess cytoplasm by spermatozoa may reflect the negative impact of cigarette smoking on sperm quality, function, and fertility potential in men. CD/defective CD should be evaluated as an independent variable (parameter). We suggest that cutoff values of normality and abnormality of percentage of spermatozoa with CD and defective CD be clearly defined, as defective CDs not only affect the spermatozoa carrying them but may also affect the normal ones.
{"title":"Evaluation of the association of cigarette smoking with retention of excess cytoplasm by spermatozoa in infertile men","authors":"A. Hassanin, Heba G. El-Shirbini","doi":"10.1097/01.XHA.0000466753.24941.2a","DOIUrl":"https://doi.org/10.1097/01.XHA.0000466753.24941.2a","url":null,"abstract":"PurposeThe aim of the study was to evaluate the effect of smoking on retention of excess cytoplasm by spermatozoa in infertile men. Patients and methodsTwo groups of idiopathic infertile men, group 1 (20 smokers) and group 2 (20 nonsmokers), were included in the study. The cytoplasmic droplet (CD)/defective CD was evaluated as an independent variable in Papanicolaou-stained seminal smears for each participant, in addition to the standard semen parameter. CD greater than one-third the sperm head size was considered defective [excess residual cytoplasm (ERC)]. ResultsDefective CD (ERC), total head defects, total tail defects, and total abnormal forms were significantly higher in the smoker group. Significant positive correlation was found between defective CD (ERC) and both the number of smoked cigarettes/day and the duration of smoking. ConclusionRetention of excess cytoplasm by spermatozoa may reflect the negative impact of cigarette smoking on sperm quality, function, and fertility potential in men. CD/defective CD should be evaluated as an independent variable (parameter). We suggest that cutoff values of normality and abnormality of percentage of spermatozoa with CD and defective CD be clearly defined, as defective CDs not only affect the spermatozoa carrying them but may also affect the normal ones.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"84 1","pages":"28–32"},"PeriodicalIF":0.0,"publicationDate":"2015-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86951219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-03-01DOI: 10.1097/01.XHA.0000459554.60016.9a
Taha A. El Far, N. Ismail, S. Hassan, A. Fathy
IntroductionThe fifth edition of the WHO semen analysis manual provides the lowest reference limits for semen parameters. Until now, a reference for Egyptian semen has not been established. PurposeThe aim of the study was to determine different sperm parameters in a sample of proven fertile men in Beni Suef Governorate. Participants and methodsA total of 200 fertile men, with fertility proven by the presence of either pregnant wives or wives who had delivered not earlier than 1 year before, provided semen samples for computer-assisted semen analysis. The WHO criteria were applied. ResultsOur results were comparable to those of WHO regarding the mean values but variable with respect to the fifth percentile, which was used as a lower limit by WHO. The fifth percentiles for volume, concentration, and morphology (1.8 ml, 20.85 million/ml, 7.58% respectively) were higher than the WHO reference values (1.5 ml, 15 million/ml, and 4%, respectively). But our fifth percentiles for total and progressive motility (34.45 and 27.7%, respectively) were below the WHO lower limits (40 and 32%, respectively). There was no significant difference in semen parameters between age groups. ConclusionOur results may serve as a guide for future studies on semen quality in Egypt.
{"title":"Semen parameters in a sample of fertile Egyptian men in Beni Suef Governorate","authors":"Taha A. El Far, N. Ismail, S. Hassan, A. Fathy","doi":"10.1097/01.XHA.0000459554.60016.9a","DOIUrl":"https://doi.org/10.1097/01.XHA.0000459554.60016.9a","url":null,"abstract":"IntroductionThe fifth edition of the WHO semen analysis manual provides the lowest reference limits for semen parameters. Until now, a reference for Egyptian semen has not been established. PurposeThe aim of the study was to determine different sperm parameters in a sample of proven fertile men in Beni Suef Governorate. Participants and methodsA total of 200 fertile men, with fertility proven by the presence of either pregnant wives or wives who had delivered not earlier than 1 year before, provided semen samples for computer-assisted semen analysis. The WHO criteria were applied. ResultsOur results were comparable to those of WHO regarding the mean values but variable with respect to the fifth percentile, which was used as a lower limit by WHO. The fifth percentiles for volume, concentration, and morphology (1.8 ml, 20.85 million/ml, 7.58% respectively) were higher than the WHO reference values (1.5 ml, 15 million/ml, and 4%, respectively). But our fifth percentiles for total and progressive motility (34.45 and 27.7%, respectively) were below the WHO lower limits (40 and 32%, respectively). There was no significant difference in semen parameters between age groups. ConclusionOur results may serve as a guide for future studies on semen quality in Egypt.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"142 1","pages":"13–17"},"PeriodicalIF":0.0,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91064000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-03-01DOI: 10.1097/01.XHA.0000459553.60734.93
E. S. Hewedy, Mohammad A. Sweilm, Naeim M. Abd El-Naby, A. Hassan, M. Fawzy, Mohamed S. Agrama
BackgroundVaricocele is the most widespread andrological disease and also the most frequent cause of infertility in men. Inhibin-B is secreted from Sertoli cells under germ cell control. It is accepted as the most important marker for normal spermatogenesis. Aim of the workThe aim of the study was to evaluate the serum and seminal plasma inhibin-B level in infertile men with varicocele and to compare its level with normal fertile men, in addition to its level with serum follicle stimulating hormone (FSH) and seminal parameters. Patients and methodsTwenty-five infertile patients with varicocele were collected from the outpatient clinic of Dermatology and Venereology Department, Tanta University Hospital, in addition to 15 healthy fertile men with normal semen analysis and without varicocele. They were subjected to complete history taking, thorough general and genital examination, semen analysis, and determination of serum and seminal plasma inhibin-B and serum FSH level by enzyme-linked immunosorbent assay. ResultsThis study did not show significant differences in serum and seminal plasma inhibin-B level between varicocele patients and controls. Moreover, serum inhibin-B was not correlated with seminal parameters, whereas seminal plasma inhibin-B exhibited a significant positive correlation with sperm count and a significant negative correlation with abnormal sperm forms. In contrast, no significant correlation could be detected between serum and seminal plasma inhibin-B and serum FSH in varicocele patients. ConclusionSeminal plasma inhibin-B is a good marker of spermatogenesis in infertile patients with varicocele, but no relationship was found between serum inhibin, seminal plasma inhibin, and FSH. Hence, further studies are needed to elucidate whether varicocele, a frequently found pathology, may add to its multifactorial etiology an alteration in the negative feedback mechanism involved in the FSH.
{"title":"Serum and seminal plasma inhibin-B level in infertile men with varicocele","authors":"E. S. Hewedy, Mohammad A. Sweilm, Naeim M. Abd El-Naby, A. Hassan, M. Fawzy, Mohamed S. Agrama","doi":"10.1097/01.XHA.0000459553.60734.93","DOIUrl":"https://doi.org/10.1097/01.XHA.0000459553.60734.93","url":null,"abstract":"BackgroundVaricocele is the most widespread andrological disease and also the most frequent cause of infertility in men. Inhibin-B is secreted from Sertoli cells under germ cell control. It is accepted as the most important marker for normal spermatogenesis. Aim of the workThe aim of the study was to evaluate the serum and seminal plasma inhibin-B level in infertile men with varicocele and to compare its level with normal fertile men, in addition to its level with serum follicle stimulating hormone (FSH) and seminal parameters. Patients and methodsTwenty-five infertile patients with varicocele were collected from the outpatient clinic of Dermatology and Venereology Department, Tanta University Hospital, in addition to 15 healthy fertile men with normal semen analysis and without varicocele. They were subjected to complete history taking, thorough general and genital examination, semen analysis, and determination of serum and seminal plasma inhibin-B and serum FSH level by enzyme-linked immunosorbent assay. ResultsThis study did not show significant differences in serum and seminal plasma inhibin-B level between varicocele patients and controls. Moreover, serum inhibin-B was not correlated with seminal parameters, whereas seminal plasma inhibin-B exhibited a significant positive correlation with sperm count and a significant negative correlation with abnormal sperm forms. In contrast, no significant correlation could be detected between serum and seminal plasma inhibin-B and serum FSH in varicocele patients. ConclusionSeminal plasma inhibin-B is a good marker of spermatogenesis in infertile patients with varicocele, but no relationship was found between serum inhibin, seminal plasma inhibin, and FSH. Hence, further studies are needed to elucidate whether varicocele, a frequently found pathology, may add to its multifactorial etiology an alteration in the negative feedback mechanism involved in the FSH.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"1 1","pages":"18–22"},"PeriodicalIF":0.0,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75083963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-03-01DOI: 10.1097/01.XHA.0000461958.94152.e0
I. Younis, M. Ibrahim
BackgroundSexual arousal is accompanied by some typical physiological reaction patterns. Another typical feature of sexual intercourse is the sounds produced commonly by women [coital vocalizations (CV)]. The literature on this aspect of female sexuality is meager. It will be useful to add some knowledge to this field as absence of CV usually reflects a defect in the sexual relations, which can have a negative impact on both partners. Participants and methodsOne hundred married women attending the outpatient clinic of Benha University Hospital, Egypt, participated in this study. A self-report questionnaire, designed by the investigators, was used. It included 20 questions covering different aspects of CV. ResultsThe most common type of CV was moan/groan, followed by words. CV were mainly produced by women, most commonly occurring during thrusting, and most women believed that CV accelerated their husbands’ ejaculation. Also, most women believed that CV increased desire for further sexual activity and increased satisfaction with intercourse. CV did not change with age in most women. Sexual performance appeared to be more gratifying for the women in group I (CV producers) than for the women in group II (nonvocalizers). This is evidenced by the higher figures for sexual activity obtained from group I, for example higher coital frequency, more frequent desire, and a better ability to lubricate and to reach an orgasm. However, there was no statistically significant difference in these figures between both groups. ConclusionWe got the impression that women producing CV seem to be better sexual partners. They enjoy the act more and bring more joy and satisfaction to their partners. Clinically, the wife, in cases of sexual dysfunction, should be informed of the importance of CV and may be advised to vocalize for herself and her partner’s satisfaction.
{"title":"A beautiful noise: women’s coital vocalizations","authors":"I. Younis, M. Ibrahim","doi":"10.1097/01.XHA.0000461958.94152.e0","DOIUrl":"https://doi.org/10.1097/01.XHA.0000461958.94152.e0","url":null,"abstract":"BackgroundSexual arousal is accompanied by some typical physiological reaction patterns. Another typical feature of sexual intercourse is the sounds produced commonly by women [coital vocalizations (CV)]. The literature on this aspect of female sexuality is meager. It will be useful to add some knowledge to this field as absence of CV usually reflects a defect in the sexual relations, which can have a negative impact on both partners. Participants and methodsOne hundred married women attending the outpatient clinic of Benha University Hospital, Egypt, participated in this study. A self-report questionnaire, designed by the investigators, was used. It included 20 questions covering different aspects of CV. ResultsThe most common type of CV was moan/groan, followed by words. CV were mainly produced by women, most commonly occurring during thrusting, and most women believed that CV accelerated their husbands’ ejaculation. Also, most women believed that CV increased desire for further sexual activity and increased satisfaction with intercourse. CV did not change with age in most women. Sexual performance appeared to be more gratifying for the women in group I (CV producers) than for the women in group II (nonvocalizers). This is evidenced by the higher figures for sexual activity obtained from group I, for example higher coital frequency, more frequent desire, and a better ability to lubricate and to reach an orgasm. However, there was no statistically significant difference in these figures between both groups. ConclusionWe got the impression that women producing CV seem to be better sexual partners. They enjoy the act more and bring more joy and satisfaction to their partners. Clinically, the wife, in cases of sexual dysfunction, should be informed of the importance of CV and may be advised to vocalize for herself and her partner’s satisfaction.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"97 1","pages":"5–12"},"PeriodicalIF":0.0,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75941038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-03-01DOI: 10.1097/01.XHA.0000461960.92367.16
M. Roaiah, A. Hassanin, A. A. Abd_El Aal, A. Z. Hamid
PurposeBoth Peyronie’s disease (PD) and late onset hypogonadism occur, most likely, in middle-aged and old men. It is well-known that testosterone declines with age and is implicated in wound healing; therefore, the role of testosterone deficiency in the development and severity of PD was investigated. Patients and methodsA prospective controlled study was carried out on 25 participants, 15 with PD and 10 controls. PD patient history questionnaire was obtained, and PD was later confirmed by physical examination. The total and free serum testosterone levels were estimated. Evaluation of the differences between the two groups was carried out. In PD patients, the plaque area and penile curvature were assessed. PD patients were further classified into two subgroups: subgroup A (low testosterone level) and subgroup B (normal testosterone level). Evaluation of the differences between the two subgroups, such as the plaque area and penile curvature, was carried out. ResultsA significantly lower free and total serum testosterone levels were found in the PD patient group compared with the control group (P<0.05). Moreover, it was found that 60% of patients with PD had low serum testosterone levels. On comparing the subgroups, the plaque size was found to be significantly larger and the mean degree of penile curvature was found to be significantly greater in subgroup A. ConclusionTestosterone deficiency may play a role in the development of PD and in the development of more severe manifestations of the disease, such as plaque size and penile curvature. However, further studies with larger samples are encouraged to confirm these conclusions.
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