Pub Date : 2018-06-01DOI: 10.21608/HA.2018.4106.1030
M. Farid, A. Ragab, Ahmed Sayed Abdel Baset, S. G. Din
patients with varicocele.Patients and Methods: A total of 60 patients with infertility and clinical varicocele were assessed in comparison with 60 healthy fertile controls. The two groups were evaluated by history taking, clinical examination as well as semen analysis (WHO, 2010). Color Doppler ultrasonography was performed to assess the rate of TM in both groups. Finally, hormonal profile was studied for those with infertility and sperm concentration less than 10 million/ml.Results: Sonographic features of TM were revealed in 4/ 60 (6.7%) of cases with varicocele. However, this finding was of statistical insignificance (P=0.081). Of those cases, three had left varicocele associated with ipsilateral TM and one had bilateral varicocele and bilateral TM, whereas there was no sonographic evidence of TM in controls. Cases with TM were associated with primary infertility. Conclusion: In brief, this study demonstrated that only four of the 60 patients revealed intratesticular calcifications, and this was statistically insignificant. Moreover, there were also 23 healthy controls with subclinical varicoceles that were detected by scrotal duplex. However, TM was not detected in them. Thus, association of TM with varicocele is controversial. Finally, we recommend further studies to replicate this finding and to perform studies that compare fertile men and infertile patients with varicoceles to replicate this finding.
{"title":"Association between testicular microlithiasis and varicocele in infertile men: A comparative study","authors":"M. Farid, A. Ragab, Ahmed Sayed Abdel Baset, S. G. Din","doi":"10.21608/HA.2018.4106.1030","DOIUrl":"https://doi.org/10.21608/HA.2018.4106.1030","url":null,"abstract":"patients with varicocele.Patients and Methods: A total of 60 patients with infertility and clinical varicocele were assessed in comparison with 60 healthy fertile controls. The two groups were evaluated by history taking, clinical examination as well as semen analysis (WHO, 2010). Color Doppler ultrasonography was performed to assess the rate of TM in both groups. Finally, hormonal profile was studied for those with infertility and sperm concentration less than 10 million/ml.Results: Sonographic features of TM were revealed in 4/ 60 (6.7%) of cases with varicocele. However, this finding was of statistical insignificance (P=0.081). Of those cases, three had left varicocele associated with ipsilateral TM and one had bilateral varicocele and bilateral TM, whereas there was no sonographic evidence of TM in controls. Cases with TM were associated with primary infertility. Conclusion: In brief, this study demonstrated that only four of the 60 patients revealed intratesticular calcifications, and this was statistically insignificant. Moreover, there were also 23 healthy controls with subclinical varicoceles that were detected by scrotal duplex. However, TM was not detected in them. Thus, association of TM with varicocele is controversial. Finally, we recommend further studies to replicate this finding and to perform studies that compare fertile men and infertile patients with varicoceles to replicate this finding.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"38 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81895473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-01DOI: 10.21608/HA.2018.3611.1024
H. Ghanem, A. Ragab, N. Nabil, Shimaa Hamdy, I. Fathy
Introduction: Rheumatoid arthritis (RA) is a widespread disease that has a profound effect on the patient’s quality of life.Aim:The aim was to evaluate the rate of sexual dysfunction (SD) in women with RA and to assess the possible association between SD and disease activity, severity of morning stiffness, functional disability and psychological status.Patients and Methods: A case-control study was conducted on 200 sexually active, women in the reproductive age. A total of 100 women with RA attending the rheumatology clinics of two reference hospitals in Upper Egypt and 100 arthritis-free age- and sex-matched healthy controls were compared regarding the scores of Arabic Female Sexual Function Index (ArFSFI) and Hospital anxiety and depression scale (HADS). Additionally, women with RA were evaluated via Health Assessment Questionnaire (HAQ) and Disease Activity Score (DAS-28). Results: The mean ages of patients (35.96.4± years) and controls (34.45.4± years) were insignificantly different (P>0.05). Mean FSFI total and domain scores of patients were significantly lower than controls (P<0.001). Overall, 94% of patients and 30% of controls (P<0.001) reported SD. Among women with RA (n: 100), lower SF scores were reported among those with morning stiffness (n: 14, P<0.05). Women with RA who exhibited SD had higher levels of anxiety, depression, and disease activity (P<0.05) than those without SD. However, both subgroups were not different regarding HAQ. Conclusion: The present study found an SD rate of 94% among sexually active women with RA. RA could have an extensively negative effect on all aspects of female sexuality, particularly on lubrication and orgasm dimensions. Moreover, SD in women with RA is significantly associated with disease activity, severity of morning stiffness, depression, and anxiety levels, but not with functional disability (HAQ).
{"title":"Sexual dysfunction in women in the reproductive age with rheumatoid arthritis: A case-control study","authors":"H. Ghanem, A. Ragab, N. Nabil, Shimaa Hamdy, I. Fathy","doi":"10.21608/HA.2018.3611.1024","DOIUrl":"https://doi.org/10.21608/HA.2018.3611.1024","url":null,"abstract":"Introduction: Rheumatoid arthritis (RA) is a widespread disease that has a profound effect on the patient’s quality of life.Aim:The aim was to evaluate the rate of sexual dysfunction (SD) in women with RA and to assess the possible association between SD and disease activity, severity of morning stiffness, functional disability and psychological status.Patients and Methods: A case-control study was conducted on 200 sexually active, women in the reproductive age. A total of 100 women with RA attending the rheumatology clinics of two reference hospitals in Upper Egypt and 100 arthritis-free age- and sex-matched healthy controls were compared regarding the scores of Arabic Female Sexual Function Index (ArFSFI) and Hospital anxiety and depression scale (HADS). Additionally, women with RA were evaluated via Health Assessment Questionnaire (HAQ) and Disease Activity Score (DAS-28). Results: The mean ages of patients (35.96.4± years) and controls (34.45.4± years) were insignificantly different (P>0.05). Mean FSFI total and domain scores of patients were significantly lower than controls (P<0.001). Overall, 94% of patients and 30% of controls (P<0.001) reported SD. Among women with RA (n: 100), lower SF scores were reported among those with morning stiffness (n: 14, P<0.05). Women with RA who exhibited SD had higher levels of anxiety, depression, and disease activity (P<0.05) than those without SD. However, both subgroups were not different regarding HAQ. Conclusion: The present study found an SD rate of 94% among sexually active women with RA. RA could have an extensively negative effect on all aspects of female sexuality, particularly on lubrication and orgasm dimensions. Moreover, SD in women with RA is significantly associated with disease activity, severity of morning stiffness, depression, and anxiety levels, but not with functional disability (HAQ).","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"40 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84477202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-01DOI: 10.21608/HA.2018.1368.1011
H. A. Hamed, Nashaat Nabil Esmail, Marwa Ahmed Aldardiry, Rashad M. Mostafa
Backgroud: Trichomoniasis is not a reportable infection and its control received relatively little emphasis from public health STD control programs although it is the most common curable sexually transmitted disease in young sexually active women. Purpose: To diagnose trichomoniasis among women attending family planning units and to identify the possible risk factors affecting the disease. Materials and Methods: The present work was carried on 100 married women attending family planning units in ELFayoum Governorate. Diagnosis of trichomoniasis was done by direct wet mount microscopy, Geimsa staining and modified Field Stain. Results: The women ages ranged from 19 to 49 years old. The mean women age was 29.7± 7.1 years old. The majority of women (62%) had residence in rural areas and housewives (82%). The educational level ranged from illiteracy to high collage. Illiterate women were (14%). Seventy four women (74%) had educational level within 8 years of schooling. About 12% of women had high level education. Only six women (6%) had diabetes mellitus. The symptoms reported by the examined women include: (60%) increased vaginal discharge and itching, (31%) genital malodor. While (29%) women were presented with dyspareunia, (33%) presented with dysuria and (9%) with lower abdominal pain. This study demonstrated that Modified Field Stain ( MF) stain, apart from being a rapid stain (20 s) in comparison to Giemsa stain (20 min.), confers sharper staining contrast, which differentiates the nucleus and the cytoplasm of the organism and demonstrated that Vacuoles are more clearly visible in parasites with MF than those stained with Giemsa. Conclusion: The results of the present study pointed to the benefits of use of modified Field stain in diagnosis of T. vaginalis infection.
{"title":"The use of modified Field’s stain in diagnosis of Trichomonas vaginalis","authors":"H. A. Hamed, Nashaat Nabil Esmail, Marwa Ahmed Aldardiry, Rashad M. Mostafa","doi":"10.21608/HA.2018.1368.1011","DOIUrl":"https://doi.org/10.21608/HA.2018.1368.1011","url":null,"abstract":"Backgroud: Trichomoniasis is not a reportable infection and its control received relatively little emphasis from public health STD control programs although it is the most common curable sexually transmitted disease in young sexually active women. Purpose: To diagnose trichomoniasis among women attending family planning units and to identify the possible risk factors affecting the disease. Materials and Methods: The present work was carried on 100 married women attending family planning units in ELFayoum Governorate. Diagnosis of trichomoniasis was done by direct wet mount microscopy, Geimsa staining and modified Field Stain. Results: The women ages ranged from 19 to 49 years old. The mean women age was 29.7± 7.1 years old. The majority of women (62%) had residence in rural areas and housewives (82%). The educational level ranged from illiteracy to high collage. Illiterate women were (14%). Seventy four women (74%) had educational level within 8 years of schooling. About 12% of women had high level education. Only six women (6%) had diabetes mellitus. The symptoms reported by the examined women include: (60%) increased vaginal discharge and itching, (31%) genital malodor. While (29%) women were presented with dyspareunia, (33%) presented with dysuria and (9%) with lower abdominal pain. This study demonstrated that Modified Field Stain ( MF) stain, apart from being a rapid stain (20 s) in comparison to Giemsa stain (20 min.), confers sharper staining contrast, which differentiates the nucleus and the cytoplasm of the organism and demonstrated that Vacuoles are more clearly visible in parasites with MF than those stained with Giemsa. Conclusion: The results of the present study pointed to the benefits of use of modified Field stain in diagnosis of T. vaginalis infection.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"40 1","pages":"19-29"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91393234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-01DOI: 10.21608/HA.2018.2385.1019
A. Salam, Mohamed Ahmed
Ischemic priapism is considered as the most common type of priapism (accounting for >95% of cases) that is due to obstruction of venous outflows from leading to impaired perfusion of cavernous tissue with subsequent hypoxia, hypercapnia and acidosis, ending in fibrosis and erectile dysfunction. Several causes have been attributed to cause ischemic priapism including hemoglobinopathies (including sickle cell anemia and thalassemias), hypercoagulable status, neoplastic syndromes, compressive pelvi-abdominal masses, and spinal cord injuries. In addition, the use of some drugs may lead to iatrogenic veno-occlusive priapism including use of some recreational drugs (cocaine, heroin, opiates, and cannabis) and medications (intracavernosal injections of papaverine, phentolamine, and prostaglandin E1, anticoagulants, α-blockers, antidepressants, and antipsychotics). However, ischemic priapism has been identified as idiopathic in most cases as no specific cause could be identified. Urgent management of ischemic priapism with aspiration/ irrigation along with the use of sympathomimetic agents gives better outcome. However, if left untreated, resolution may take days and erectile dysfunction invariably results that may require penile prosthesis implantation [2].
{"title":"Chlorpromazine induced priapism : An up to date mini-review","authors":"A. Salam, Mohamed Ahmed","doi":"10.21608/HA.2018.2385.1019","DOIUrl":"https://doi.org/10.21608/HA.2018.2385.1019","url":null,"abstract":"Ischemic priapism is considered as the most common type of priapism (accounting for >95% of cases) that is due to obstruction of venous outflows from leading to impaired perfusion of cavernous tissue with subsequent hypoxia, hypercapnia and acidosis, ending in fibrosis and erectile dysfunction. Several causes have been attributed to cause ischemic priapism including hemoglobinopathies (including sickle cell anemia and thalassemias), hypercoagulable status, neoplastic syndromes, compressive pelvi-abdominal masses, and spinal cord injuries. In addition, the use of some drugs may lead to iatrogenic veno-occlusive priapism including use of some recreational drugs (cocaine, heroin, opiates, and cannabis) and medications (intracavernosal injections of papaverine, phentolamine, and prostaglandin E1, anticoagulants, α-blockers, antidepressants, and antipsychotics). However, ischemic priapism has been identified as idiopathic in most cases as no specific cause could be identified. Urgent management of ischemic priapism with aspiration/ irrigation along with the use of sympathomimetic agents gives better outcome. However, if left untreated, resolution may take days and erectile dysfunction invariably results that may require penile prosthesis implantation [2].","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"36 1","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76795171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-01DOI: 10.21608/HA.2018.1894.1017
I. Younis, S. Abdel-Rahman, Fatma M. El-Esawi, Mona A. Al-Awady
Backgroud: Masturbation has been stigmatized over the years. Research work in many countries indicates that men significantly more likely than women to report having ever masturbated and associations between masturbation and various sociodemographic factors were identified.Objective: This study was carried out intending to provide information about the frequency of masturbation in a sample of Egyptian women and the views of women about it.Patients and Methods: This cross-sectional observational study included 286 women who filled a self-report questionnaire covering four domains: epidemiology, sexual activity, assessment of masturbation practice, and probing of the religious attitudes of the participants towards masturbation.Results: Among our participants, 53.5% admitted practicing masturbation. The most common frequency of masturbation was once per week (44.2%). Masturbation was considered a substitute for absence of husband or his unwillingness to have sex by 44.2% of participants. Masturbation was considered ‘haram’ (prohibited) by 39.2% of participants and 77.5% said it caused them to feel guilty. The commonest age group practicing masturbation was 20–29 years and the most common educational level for masturbators was women with a university degree (24.5%). Married women admitted to having masturbated more than virgins (32.9 vs. 10.1%).Conclusion: Masturbation is a relatively common practice among this sample of Egyptian women. Most women considered masturbation ‘haram’ and felt guilty about it. The most common age for practicing masturbation was between 20 and 29 years and the most common educational level for masturbators was a university degree and married women were the most common group to admit masturbation.
{"title":"Solo sex: Masturbation in a sample of Egyptian women","authors":"I. Younis, S. Abdel-Rahman, Fatma M. El-Esawi, Mona A. Al-Awady","doi":"10.21608/HA.2018.1894.1017","DOIUrl":"https://doi.org/10.21608/HA.2018.1894.1017","url":null,"abstract":"Backgroud: Masturbation has been stigmatized over the years. Research work in many countries indicates that men significantly more likely than women to report having ever masturbated and associations between masturbation and various sociodemographic factors were identified.Objective: This study was carried out intending to provide information about the frequency of masturbation in a sample of Egyptian women and the views of women about it.Patients and Methods: This cross-sectional observational study included 286 women who filled a self-report questionnaire covering four domains: epidemiology, sexual activity, assessment of masturbation practice, and probing of the religious attitudes of the participants towards masturbation.Results: Among our participants, 53.5% admitted practicing masturbation. The most common frequency of masturbation was once per week (44.2%). Masturbation was considered a substitute for absence of husband or his unwillingness to have sex by 44.2% of participants. Masturbation was considered ‘haram’ (prohibited) by 39.2% of participants and 77.5% said it caused them to feel guilty. The commonest age group practicing masturbation was 20–29 years and the most common educational level for masturbators was women with a university degree (24.5%). Married women admitted to having masturbated more than virgins (32.9 vs. 10.1%).Conclusion: Masturbation is a relatively common practice among this sample of Egyptian women. Most women considered masturbation ‘haram’ and felt guilty about it. The most common age for practicing masturbation was between 20 and 29 years and the most common educational level for masturbators was a university degree and married women were the most common group to admit masturbation.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"80 1","pages":"11-18"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83948289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-03-01DOI: 10.21608/HA.2017.1241.1009
N. Ismail, Rashad M. Mostafa, Maha A. Fouad
{"title":"Seroprevalence of HCV, HBV, HIV and syphilis among blood donors at Beni-Seuf University Hospital blood bank","authors":"N. Ismail, Rashad M. Mostafa, Maha A. Fouad","doi":"10.21608/HA.2017.1241.1009","DOIUrl":"https://doi.org/10.21608/HA.2017.1241.1009","url":null,"abstract":"","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"33 1","pages":"4-7"},"PeriodicalIF":0.0,"publicationDate":"2018-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74803735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-01DOI: 10.21608/HA.2017.1628.1014
A. Elsamanoudy, D. Shaalan, S. A. El-khair, M. Gaballah, A. State, A. Helaly
Introduction: Male factor is responsible for about half of infertility problems. However, the reasons for the decrease in male fertility are still broadly unclear. The mechanisms of how smoking may impact male fertility have not been established. However, with its influence on different semen parameters, it is regarded as a risk factor for infertility.Aim: To investigate the effect of chronic smoking on spermatozoa NRF2 expression and DNA fragmentation in infertile men with apparently normal seminogram and to determine if NRF2 expression and DNA fragmentation markers could be possible predictors of the impact of chronic cigarette smoking on male fertility.Methods: Semen samples were collected from 170 subjects; 65 nonsmokers (40 fertile and 25 infertile) and 105 smokers (25 fertile and 80 infertile). NRF2 gene expression, 8-OHdG and DNA fragmentation were assayed.Results: There were significant increases in 8-OHdG and %DNA fragmentation with a significant decrease in NRF2 gene expression in infertile smokers. ROC curve analysis of spermatozoa NRF2 gene expression showed 95% sensitivity 93.3% specificity at cutoff value ≤0. 931 (p 19.33 pg/ml predicting the detrimental effect of smoking on spermatozoa DNA.Conclusion: Chronic cigarette smoking may be a hidden causative mechanism of delayed fertility. Spermatozoa NRF2 gene expression and seminal 8-OHdG levels may serve as sensitive diagnostic indicators predicting smoking induced infertility. So, the presence of normal seminal parameters could not be an exclusion of potential effect of chronic smoking on male fertility.
{"title":"NRF2 gene expression and DNA fragmentation markers as possible predictors of chronic smoking induced spermatozoa dysfunction in infertility with normal seminogram","authors":"A. Elsamanoudy, D. Shaalan, S. A. El-khair, M. Gaballah, A. State, A. Helaly","doi":"10.21608/HA.2017.1628.1014","DOIUrl":"https://doi.org/10.21608/HA.2017.1628.1014","url":null,"abstract":"Introduction: Male factor is responsible for about half of infertility problems. However, the reasons for the decrease in male fertility are still broadly unclear. The mechanisms of how smoking may impact male fertility have not been established. However, with its influence on different semen parameters, it is regarded as a risk factor for infertility.Aim: To investigate the effect of chronic smoking on spermatozoa NRF2 expression and DNA fragmentation in infertile men with apparently normal seminogram and to determine if NRF2 expression and DNA fragmentation markers could be possible predictors of the impact of chronic cigarette smoking on male fertility.Methods: Semen samples were collected from 170 subjects; 65 nonsmokers (40 fertile and 25 infertile) and 105 smokers (25 fertile and 80 infertile). NRF2 gene expression, 8-OHdG and DNA fragmentation were assayed.Results: There were significant increases in 8-OHdG and %DNA fragmentation with a significant decrease in NRF2 gene expression in infertile smokers. ROC curve analysis of spermatozoa NRF2 gene expression showed 95% sensitivity 93.3% specificity at cutoff value ≤0. 931 (p 19.33 pg/ml predicting the detrimental effect of smoking on spermatozoa DNA.Conclusion: Chronic cigarette smoking may be a hidden causative mechanism of delayed fertility. Spermatozoa NRF2 gene expression and seminal 8-OHdG levels may serve as sensitive diagnostic indicators predicting smoking induced infertility. So, the presence of normal seminal parameters could not be an exclusion of potential effect of chronic smoking on male fertility.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"16 10","pages":"127-135"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91500305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-01DOI: 10.21608/HA.2017.1189.1006
E. Sakhaee, L. Emadi, Heydar Khalili Bagaloy, N. Abbasi
Introduction: the point of the present survey was to evaluate time and dose-dependent adverse effects of four restorative herbs on male reproductive system.Methods: the study involved of seventeen distinctive gatherings of ten mice as takes after: group C1 to C4 (Cuminum cyminum), which received 0.1 ml Cuminum cyminum essential oil at dosage of 0.1, 1, 10 and 100 mg/kg/day, respectively. Group R1 to R4 (Rosa damascene), which received 0.1 ml Rosa damascene essential oil at dosage of 0.1, 1, 10 and 100 mg/kg/day, respectively. Group Z1 to Z4 (Zataria multiflora), which received 0.1 ml Zataria multiflora ethanolic extract at dosage of 100, 200, 400 and 800 mg/kg/day, respectively. Group O1 to O4 (Origanum vulgare), which received 0.1 ml Origanum vulgare ethanolic extract at dose of 100, 200, 400 and 800 mg/kg/day, respectively and finally group Normal which got similar amount of normal saline.Results: the results demonstrated that sperm density, mobility and viability in groups R4, O4, Z2, Z3, Z4, C2, C3 and C4 after 4 weeks were altogether diminished in comparison with normal group.Discussion: according to the results, mentioned medicinal plants should not be used frequently for prolonged duration
{"title":"Time and dose-dependent adverse effects of four medicinal plants on male reproductive system","authors":"E. Sakhaee, L. Emadi, Heydar Khalili Bagaloy, N. Abbasi","doi":"10.21608/HA.2017.1189.1006","DOIUrl":"https://doi.org/10.21608/HA.2017.1189.1006","url":null,"abstract":"Introduction: the point of the present survey was to evaluate time and dose-dependent adverse effects of four restorative herbs on male reproductive system.Methods: the study involved of seventeen distinctive gatherings of ten mice as takes after: group C1 to C4 (Cuminum cyminum), which received 0.1 ml Cuminum cyminum essential oil at dosage of 0.1, 1, 10 and 100 mg/kg/day, respectively. Group R1 to R4 (Rosa damascene), which received 0.1 ml Rosa damascene essential oil at dosage of 0.1, 1, 10 and 100 mg/kg/day, respectively. Group Z1 to Z4 (Zataria multiflora), which received 0.1 ml Zataria multiflora ethanolic extract at dosage of 100, 200, 400 and 800 mg/kg/day, respectively. Group O1 to O4 (Origanum vulgare), which received 0.1 ml Origanum vulgare ethanolic extract at dose of 100, 200, 400 and 800 mg/kg/day, respectively and finally group Normal which got similar amount of normal saline.Results: the results demonstrated that sperm density, mobility and viability in groups R4, O4, Z2, Z3, Z4, C2, C3 and C4 after 4 weeks were altogether diminished in comparison with normal group.Discussion: according to the results, mentioned medicinal plants should not be used frequently for prolonged duration","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"85 1","pages":"136-142"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76337852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-01DOI: 10.21608/HA.2017.1788.1015
O. Shaeer, K. Shaeer, M. Fode, E. Şerefoğlu
Introduction: The Global Online Sexuality Survey (GOSS) is an ongoing online epidemiologic study of male and female sexuality launched across the globe. The first launch was in the Middle East in 2010 followed by USA in 2011. This is the report on trends in male sexuality and prevalence and risk factors for erectile dysfunction (ED) in USA; 2015.Patients and Methods: English-speaking web surfers in the USA were recruited for GOOS 2015 by an international online survey service provider, with age and ethnicity distribution matching that of the general US population. A total of 100 questions were offered to the participants, including the abbreviated international index of erectile function, risk factors for ED, ejaculatory function, therapeutic trends, sexual preferences and sexual orientation.Results: A total of 610 men with a median age of 44 years (range 18-82). Of the participants, 90.2% described themselves as exclusively or predominantly heterosexual and 52.3% were married whereas 20.1% had multiple partners simultaneously, 54% had experienced one-night stands, with 33% never or rarely using condom on those occasions. ED was encountered in 55.4% of the participants. Some risk factors had a statistically significant influence on ED prevalence including diabetes, smoking, low desire, dissatisfaction with penile size and multiplicity of partners.Conclusion: ED seems to affect 55.4 % of males in USA; in 2015, with an association to diabetes mellitus, obesity, hypothyroidism, subjective impression of having premature ejaculation, low desire, difficult urination, smoking, dissatisfaction with penile size and multiplicity of partners, with emphasis on online cohorts being heavily weighted towards younger and better educated individuals (only 2.1% in the age of 60 and up).
{"title":"The Global Online Sexuality Survey (GOSS) 2015: Erectile Dysfunction Among English-Speaking Internet Users in the United States","authors":"O. Shaeer, K. Shaeer, M. Fode, E. Şerefoğlu","doi":"10.21608/HA.2017.1788.1015","DOIUrl":"https://doi.org/10.21608/HA.2017.1788.1015","url":null,"abstract":"Introduction: The Global Online Sexuality Survey (GOSS) is an ongoing online epidemiologic study of male and female sexuality launched across the globe. The first launch was in the Middle East in 2010 followed by USA in 2011. This is the report on trends in male sexuality and prevalence and risk factors for erectile dysfunction (ED) in USA; 2015.Patients and Methods: English-speaking web surfers in the USA were recruited for GOOS 2015 by an international online survey service provider, with age and ethnicity distribution matching that of the general US population. A total of 100 questions were offered to the participants, including the abbreviated international index of erectile function, risk factors for ED, ejaculatory function, therapeutic trends, sexual preferences and sexual orientation.Results: A total of 610 men with a median age of 44 years (range 18-82). Of the participants, 90.2% described themselves as exclusively or predominantly heterosexual and 52.3% were married whereas 20.1% had multiple partners simultaneously, 54% had experienced one-night stands, with 33% never or rarely using condom on those occasions. ED was encountered in 55.4% of the participants. Some risk factors had a statistically significant influence on ED prevalence including diabetes, smoking, low desire, dissatisfaction with penile size and multiplicity of partners.Conclusion: ED seems to affect 55.4 % of males in USA; in 2015, with an association to diabetes mellitus, obesity, hypothyroidism, subjective impression of having premature ejaculation, low desire, difficult urination, smoking, dissatisfaction with penile size and multiplicity of partners, with emphasis on online cohorts being heavily weighted towards younger and better educated individuals (only 2.1% in the age of 60 and up).","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"3 1","pages":"111-119"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78915651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2017-12-01DOI: 10.21608/HA.2017.1554.1012
S. Ismail, A. Mahran, E. Mosaad, Suzan Elsayed
Introduction: Adipokines are differently regulated in the male reproductive tract and they were reported to affect sperm functionality. Serum omentin-1 was reported to have a range of effects on various cell types.Aim: To explore the presence of omentin-1in human semen, to investigate its relation with semen parameters in both fertile and infertile men and to compare its serum and seminal plasma levels in particular conditions such as; smoking, varicocele and leukocytospermia.Methods: Thirty nine infertile and 26 fertile men were enrolled in this case control study. They were subjected to history taking, clinical/physical examination, semen analysis, and measurement of omentin-1 in serum and seminal plasma, DNA fragmentation index (DFI) and seminal reactive oxygen species (ROS).Results: Omentin-1 was detected in all analyzed semen and serum samples (n=65). The concentration of omentin-1 was significantly higher in seminal plasma than in serum. Serum and seminal omentin-1 were positively correlated with sperm concentration and percentage of progressive motility and were negatively correlated with percentage of abnormal forms, DFI and ROS. The mean seminal plasma level of omentin-1 was significantly decreased in smokers and in patients with leukocytospermia. The mean serum level of omentin-1 was significantly decreased in patients with varicocele. Both serum and seminal omentin-1 levels were significantly lower in infertile patients than fertile men.Conclusions: Semen and serum Omentin-1 correlate with semen quality. In cases of leukocytospermia and smoking, seminal omentin-1 concentrations were decreased, suggesting that it may play a regulatory role in inflammation of the male reproductive system.
{"title":"Omentin-1 in serum and seminal plasma correlate with semen quality","authors":"S. Ismail, A. Mahran, E. Mosaad, Suzan Elsayed","doi":"10.21608/HA.2017.1554.1012","DOIUrl":"https://doi.org/10.21608/HA.2017.1554.1012","url":null,"abstract":"Introduction: Adipokines are differently regulated in the male reproductive tract and they were reported to affect sperm functionality. Serum omentin-1 was reported to have a range of effects on various cell types.Aim: To explore the presence of omentin-1in human semen, to investigate its relation with semen parameters in both fertile and infertile men and to compare its serum and seminal plasma levels in particular conditions such as; smoking, varicocele and leukocytospermia.Methods: Thirty nine infertile and 26 fertile men were enrolled in this case control study. They were subjected to history taking, clinical/physical examination, semen analysis, and measurement of omentin-1 in serum and seminal plasma, DNA fragmentation index (DFI) and seminal reactive oxygen species (ROS).Results: Omentin-1 was detected in all analyzed semen and serum samples (n=65). The concentration of omentin-1 was significantly higher in seminal plasma than in serum. Serum and seminal omentin-1 were positively correlated with sperm concentration and percentage of progressive motility and were negatively correlated with percentage of abnormal forms, DFI and ROS. The mean seminal plasma level of omentin-1 was significantly decreased in smokers and in patients with leukocytospermia. The mean serum level of omentin-1 was significantly decreased in patients with varicocele. Both serum and seminal omentin-1 levels were significantly lower in infertile patients than fertile men.Conclusions: Semen and serum Omentin-1 correlate with semen quality. In cases of leukocytospermia and smoking, seminal omentin-1 concentrations were decreased, suggesting that it may play a regulatory role in inflammation of the male reproductive system.","PeriodicalId":13018,"journal":{"name":"Human Andrology","volume":"146 1","pages":"120-126"},"PeriodicalIF":0.0,"publicationDate":"2017-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74780239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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