首页 > 最新文献

IEEE Journal on Selected Areas in Communications最新文献

英文 中文
QoS-Aware and Reliable Traffic Steering for Service Function Chaining in Mobile Networks 移动网络中服务功能链的QoS感知和可靠流量导向
IF 16.4 1区 计算机科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2017-10-05 DOI: 10.1109/JSAC.2017.2760158
Ruozhou Yu, G. Xue, Xiang Zhang
The ever-increasing mobile traffic has inspired deployment of capacity and performance enhancing network services within mobile networks. Owing to recent advances in network function virtualization, such network services can be flexibly and cost-efficiently deployed in the mobile network as software components, avoiding the need for costly hardware deployment. Nevertheless, this complicates network planning by bringing the need for service function chaining. In this paper, we study mobile network planning through a software-defined approach, considering both quality-of-service and reliability of different classes of traffic. We define and formulate the traffic steering problem for service function chaining in mobile networks, which turns out to be $mathcal {NP}$ -hard. We then develop a fast approximation scheme for the problem, and evaluate its performance via extensive simulation experiments. The results show that our algorithm is near-optimal, and achieves much better performance compared with baseline algorithms.
不断增长的移动流量激发了在移动网络中部署容量和性能增强的网络服务。由于网络功能虚拟化的最新进展,这样的网络服务可以作为软件组件灵活且经济高效地部署在移动网络中,从而避免了昂贵的硬件部署的需要。然而,这带来了对服务功能链的需求,从而使网络规划复杂化。在本文中,我们通过软件定义的方法研究移动网络规划,同时考虑不同类别流量的服务质量和可靠性。我们定义并公式化了移动网络中服务功能链接的流量导向问题,该问题是$mathcal{NP}$困难的。然后,我们为该问题开发了一个快速近似方案,并通过大量的模拟实验评估其性能。结果表明,我们的算法接近最优,并且与基线算法相比取得了更好的性能。
{"title":"QoS-Aware and Reliable Traffic Steering for Service Function Chaining in Mobile Networks","authors":"Ruozhou Yu, G. Xue, Xiang Zhang","doi":"10.1109/JSAC.2017.2760158","DOIUrl":"https://doi.org/10.1109/JSAC.2017.2760158","url":null,"abstract":"The ever-increasing mobile traffic has inspired deployment of capacity and performance enhancing network services within mobile networks. Owing to recent advances in network function virtualization, such network services can be flexibly and cost-efficiently deployed in the mobile network as software components, avoiding the need for costly hardware deployment. Nevertheless, this complicates network planning by bringing the need for service function chaining. In this paper, we study mobile network planning through a software-defined approach, considering both quality-of-service and reliability of different classes of traffic. We define and formulate the traffic steering problem for service function chaining in mobile networks, which turns out to be $mathcal {NP}$ -hard. We then develop a fast approximation scheme for the problem, and evaluate its performance via extensive simulation experiments. The results show that our algorithm is near-optimal, and achieves much better performance compared with baseline algorithms.","PeriodicalId":13243,"journal":{"name":"IEEE Journal on Selected Areas in Communications","volume":"35 1","pages":"2522-2531"},"PeriodicalIF":16.4,"publicationDate":"2017-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/JSAC.2017.2760158","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47037388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 41
Cooperative Edge Caching in Software-Defined Hyper-Cellular Networks 软件定义超蜂窝网络中的协同边缘缓存
IF 16.4 1区 计算机科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2017-10-05 DOI: 10.1109/JSAC.2017.2760184
Qiang Li, Wennian Shi, Xiaohu Ge, Z. Niu
In this paper, content caching is considered in a software-defined hyper-cellular network (SD-HCN) with capacity-limited backhaul connections. To achieve efficient content caching and delivery at the network edge, an analytical framework of minimizing the average content provisioning cost of SD-HCN, e.g., latency, bandwidth, and so on, is first formulated subjected to a sum storage capacity constraint. An optimal solution to this problem requires a joint design of storage allocation and content placement at the centralized control base station (CBS) and distributed traffic base stations (TBSs), which is NP-hard in general. To provide insights, a baseline non-cooperative caching strategy is first introduced between the CBS and TBSs. Then, an efficient cooperative edge caching strategy is proposed by leveraging the vertical cooperation between the CBS and TBSs, and horizontal cooperation between the TBSs. Analytical results demonstrate that the content provisioning cost of SD-HCN is significantly reduced by using the analytically obtained optimal storage allocation between the CBS and TBSs, and the proposed cooperative edge caching strategy always outperforms the non-cooperative caching strategy. Furthermore, by switching between the vertical and horizontal cooperative caching modes, extra performance gains can be achieved by the proposed cooperative edge caching strategy.
本文研究了具有容量限制回程连接的软件定义超蜂窝网络(SD-HCN)中的内容缓存。为了在网络边缘实现高效的内容缓存和交付,首先在存储容量总和约束下,制定了最小化SD-HCN平均内容供应成本(如延迟、带宽等)的分析框架。该问题的最优解决方案需要在集中控制基站(CBS)和分布式流量基站(tbs)上联合设计存储分配和内容放置,这通常是NP-hard问题。为了提供更深入的了解,首先在CBS和tbs之间引入了一个基线非合作缓存策略。然后,利用CBS与tss之间的纵向协作和tss之间的横向协作,提出了一种高效的协同边缘缓存策略。分析结果表明,利用解析得到的最优CBS和tbs之间的存储分配,SD-HCN的内容供应成本显著降低,并且所提出的合作边缘缓存策略始终优于非合作边缘缓存策略。此外,通过在垂直和水平协作缓存模式之间切换,所提出的协作边缘缓存策略可以获得额外的性能提升。
{"title":"Cooperative Edge Caching in Software-Defined Hyper-Cellular Networks","authors":"Qiang Li, Wennian Shi, Xiaohu Ge, Z. Niu","doi":"10.1109/JSAC.2017.2760184","DOIUrl":"https://doi.org/10.1109/JSAC.2017.2760184","url":null,"abstract":"In this paper, content caching is considered in a software-defined hyper-cellular network (SD-HCN) with capacity-limited backhaul connections. To achieve efficient content caching and delivery at the network edge, an analytical framework of minimizing the average content provisioning cost of SD-HCN, e.g., latency, bandwidth, and so on, is first formulated subjected to a sum storage capacity constraint. An optimal solution to this problem requires a joint design of storage allocation and content placement at the centralized control base station (CBS) and distributed traffic base stations (TBSs), which is NP-hard in general. To provide insights, a baseline non-cooperative caching strategy is first introduced between the CBS and TBSs. Then, an efficient cooperative edge caching strategy is proposed by leveraging the vertical cooperation between the CBS and TBSs, and horizontal cooperation between the TBSs. Analytical results demonstrate that the content provisioning cost of SD-HCN is significantly reduced by using the analytically obtained optimal storage allocation between the CBS and TBSs, and the proposed cooperative edge caching strategy always outperforms the non-cooperative caching strategy. Furthermore, by switching between the vertical and horizontal cooperative caching modes, extra performance gains can be achieved by the proposed cooperative edge caching strategy.","PeriodicalId":13243,"journal":{"name":"IEEE Journal on Selected Areas in Communications","volume":"35 1","pages":"2596-2605"},"PeriodicalIF":16.4,"publicationDate":"2017-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/JSAC.2017.2760184","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43796985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 70
Stemflow: Software-Defined Inter-Datacenter Overlay as a Service Stemflow:软件定义的数据中心间覆盖即服务
IF 16.4 1区 计算机科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2017-10-05 DOI: 10.1109/JSAC.2017.2760159
Shuhao Liu, Baochun Li
Modern Internet applications are typically hosted in the public cloud, with multiple server instances running within geographically distributed datacenters. Thanks to the abundantly available bandwidth on wide-area links that interconnect these datacenters, it is conceivable that bandwidth-intensive applications may improve their performance by relaying their traffic through such an inter-datacenter network. However, there does not yet exist a cloud service that provides a turn-key solution to tap into such available bandwidth resources conveniently. In this paper, we design and implement Stemflow, a new system framework that provides Inter-Datacenter Overlay as a Service based on the software-defined networking principle. It offers an attractive foundation that helps an Internet application to transparently improve its scalability and performance by using inter-datacenter networks for its traffic. With Stemflow, all deployed server instances will construct an overlay atop an inter-datacenter network, and the routing decisions to relay application traffic are made by a centralized controller. The algorithms needed to make these decisions are customized to meet the needs of individual applications, and are cached within the data plane. We motivate and describe the design decisions, and present an extensive experimental evaluation in public cloud infrastructures, using two example applications as our case studies.
现代互联网应用程序通常托管在公共云中,多个服务器实例在地理分布的数据中心中运行。由于互连这些数据中心的广域链路上有大量可用带宽,可以想象,带宽密集型应用程序可以通过这种数据中心间网络中继其流量来提高其性能。然而,目前还不存在提供交钥匙解决方案以方便地利用此类可用带宽资源的云服务。在本文中,我们设计并实现了Stemflow,这是一种基于软件定义的网络原理提供数据中心间覆盖即服务的新系统框架。它提供了一个有吸引力的基础,可以帮助互联网应用程序通过使用数据中心间网络来处理流量,从而透明地提高其可扩展性和性能。使用Stemflow,所有部署的服务器实例都将在数据中心间网络上构建一个覆盖层,中继应用程序流量的路由决策由集中控制器做出。做出这些决策所需的算法是定制的,以满足单个应用程序的需求,并缓存在数据平面内。我们激励并描述了设计决策,并在公共云基础设施中进行了广泛的实验评估,使用了两个示例应用程序作为我们的案例研究。
{"title":"Stemflow: Software-Defined Inter-Datacenter Overlay as a Service","authors":"Shuhao Liu, Baochun Li","doi":"10.1109/JSAC.2017.2760159","DOIUrl":"https://doi.org/10.1109/JSAC.2017.2760159","url":null,"abstract":"Modern Internet applications are typically hosted in the public cloud, with multiple server instances running within geographically distributed datacenters. Thanks to the abundantly available bandwidth on wide-area links that interconnect these datacenters, it is conceivable that bandwidth-intensive applications may improve their performance by relaying their traffic through such an inter-datacenter network. However, there does not yet exist a cloud service that provides a turn-key solution to tap into such available bandwidth resources conveniently. In this paper, we design and implement Stemflow, a new system framework that provides Inter-Datacenter Overlay as a Service based on the software-defined networking principle. It offers an attractive foundation that helps an Internet application to transparently improve its scalability and performance by using inter-datacenter networks for its traffic. With Stemflow, all deployed server instances will construct an overlay atop an inter-datacenter network, and the routing decisions to relay application traffic are made by a centralized controller. The algorithms needed to make these decisions are customized to meet the needs of individual applications, and are cached within the data plane. We motivate and describe the design decisions, and present an extensive experimental evaluation in public cloud infrastructures, using two example applications as our case studies.","PeriodicalId":13243,"journal":{"name":"IEEE Journal on Selected Areas in Communications","volume":"35 1","pages":"2563-2573"},"PeriodicalIF":16.4,"publicationDate":"2017-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/JSAC.2017.2760159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44255848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Re-Designing Dynamic Content Delivery in the Light of a Virtualized Infrastructure 根据虚拟化基础架构重新设计动态内容交付
IF 16.4 1区 计算机科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2017-09-13 DOI: 10.1109/JSAC.2017.2760185
G. Siracusano, R. Bifulco, Martino Trevisan, Tobias Jacobs, Simon Kuenzer, S. Salsano, N. Blefari-Melazzi, Felipe Huici
We explore the opportunities and design options enabled by novel SDN and NFV technologies, by re-designing a dynamic content delivery network (CDN) service. Our system, named MOSTO, provides performance levels comparable to that of a regular CDN, but does not require the deployment of a large distributed infrastructure. In the process of designing the system, we identify relevant functions that could be integrated in the future Internet infrastructure. Such functions greatly simplify the design and effectiveness of services, such as MOSTO. We demonstrate our system using a mixture of simulation, emulation, testbed experiments, and by realizing a proof-of-concept deployment in a planet-wide commercial cloud system.
我们通过重新设计动态内容交付网络(CDN)服务,探索新的SDN和NFV技术带来的机遇和设计选项。我们的系统名为MOSTO,提供了与常规CDN相当的性能级别,但不需要部署大型分布式基础设施。在设计系统的过程中,我们确定了可以集成在未来互联网基础设施中的相关功能。这些功能极大地简化了MOSTO等服务的设计和有效性。我们使用模拟、仿真、试验台实验的混合方式,并通过在全球商业云系统中实现概念验证部署来展示我们的系统。
{"title":"Re-Designing Dynamic Content Delivery in the Light of a Virtualized Infrastructure","authors":"G. Siracusano, R. Bifulco, Martino Trevisan, Tobias Jacobs, Simon Kuenzer, S. Salsano, N. Blefari-Melazzi, Felipe Huici","doi":"10.1109/JSAC.2017.2760185","DOIUrl":"https://doi.org/10.1109/JSAC.2017.2760185","url":null,"abstract":"We explore the opportunities and design options enabled by novel SDN and NFV technologies, by re-designing a dynamic content delivery network (CDN) service. Our system, named MOSTO, provides performance levels comparable to that of a regular CDN, but does not require the deployment of a large distributed infrastructure. In the process of designing the system, we identify relevant functions that could be integrated in the future Internet infrastructure. Such functions greatly simplify the design and effectiveness of services, such as MOSTO. We demonstrate our system using a mixture of simulation, emulation, testbed experiments, and by realizing a proof-of-concept deployment in a planet-wide commercial cloud system.","PeriodicalId":13243,"journal":{"name":"IEEE Journal on Selected Areas in Communications","volume":"35 1","pages":"2574-2585"},"PeriodicalIF":16.4,"publicationDate":"2017-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/JSAC.2017.2760185","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49549953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Location Privacy in Mobile Edge Clouds: A Chaff-Based Approach 移动边缘云中的位置隐私:一种基于Chaff的方法
IF 16.4 1区 计算机科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2017-09-10 DOI: 10.1109/JSAC.2017.2760179
T. He, E. Ciftcioglu, Shiqiang Wang, K. Chan
In this paper, we consider user location privacy in mobile edge clouds (MECs). MECs are small clouds deployed at the network edge to offer cloud services close to mobile users, and many solutions have been proposed to maximize service locality by migrating services to follow their users. Co-location of a user and his service, however, implies that a cyber eavesdropper observing service migrations between MECs can localize the user up to one MEC coverage area, which can be fairly small (e.g., a femtocell). We consider using chaff services to defend against such an eavesdropper, with a focus on strategies to control the chaffs. Assuming the eavesdropper performs maximum likelihood detection, we consider both heuristic strategies that mimic the user’s mobility and optimized strategies designed to minimize the detection or tracking accuracy. We show that a single chaff controlled by the optimal strategy or its online variation can drive the eavesdropper’s tracking accuracy to zero when the user’s mobility is sufficiently random. We further propose extended strategies that utilize randomization to defend against an advanced eavesdropper aware of the strategy. The efficacy of our solutions is verified through both synthetic and trace-driven simulations.
在本文中,我们考虑了移动边缘云(MECs)中的用户位置隐私。MEC是部署在网络边缘的小型云,用于提供接近移动用户的云服务,已经提出了许多解决方案,通过迁移服务以跟随用户来最大限度地提高服务位置。然而,用户和他的服务的共同定位意味着,观察MEC之间的服务迁移的网络窃听者可以将用户定位到一个MEC覆盖区域,该覆盖区域可以相当小(例如,毫微微小区)。我们考虑使用箔条服务来防御这样的窃听者,重点是控制箔条的策略。假设窃听者执行最大似然检测,我们既考虑模仿用户移动性的启发式策略,也考虑设计用于最小化检测或跟踪精度的优化策略。我们证明,当用户的移动性足够随机时,由最优策略或其在线变化控制的单个箔条可以将窃听者的跟踪精度提高到零。我们进一步提出了利用随机化来防御高级窃听者的扩展策略。我们的解决方案的有效性通过合成和跟踪驱动的模拟进行了验证。
{"title":"Location Privacy in Mobile Edge Clouds: A Chaff-Based Approach","authors":"T. He, E. Ciftcioglu, Shiqiang Wang, K. Chan","doi":"10.1109/JSAC.2017.2760179","DOIUrl":"https://doi.org/10.1109/JSAC.2017.2760179","url":null,"abstract":"In this paper, we consider user location privacy in mobile edge clouds (MECs). MECs are small clouds deployed at the network edge to offer cloud services close to mobile users, and many solutions have been proposed to maximize service locality by migrating services to follow their users. Co-location of a user and his service, however, implies that a cyber eavesdropper observing service migrations between MECs can localize the user up to one MEC coverage area, which can be fairly small (e.g., a femtocell). We consider using chaff services to defend against such an eavesdropper, with a focus on strategies to control the chaffs. Assuming the eavesdropper performs maximum likelihood detection, we consider both heuristic strategies that mimic the user’s mobility and optimized strategies designed to minimize the detection or tracking accuracy. We show that a single chaff controlled by the optimal strategy or its online variation can drive the eavesdropper’s tracking accuracy to zero when the user’s mobility is sufficiently random. We further propose extended strategies that utilize randomization to defend against an advanced eavesdropper aware of the strategy. The efficacy of our solutions is verified through both synthetic and trace-driven simulations.","PeriodicalId":13243,"journal":{"name":"IEEE Journal on Selected Areas in Communications","volume":"35 1","pages":"2625-2636"},"PeriodicalIF":16.4,"publicationDate":"2017-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/JSAC.2017.2760179","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44658520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 47
EMM: Energy-Aware Mobility Management for Mobile Edge Computing in Ultra Dense Networks EMM:超密集网络中移动边缘计算的能量感知移动管理
IF 16.4 1区 计算机科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2017-09-08 DOI: 10.1109/JSAC.2017.2760160
Yuxuan Sun, Sheng Zhou, Jie Xu
Merging mobile edge computing (MEC) functionality with the dense deployment of base stations (BSs) provides enormous benefits such as a real proximity, low latency access to computing resources. However, the envisioned integration creates many new challenges, among which mobility management (MM) is a critical one. Simply applying existing radio access-oriented MM schemes leads to poor performance mainly due to the co-provisioning of radio access and computing services of the MEC-enabled BSs. In this paper, we develop a novel user-centric energy-aware mobility management (EMM) scheme, in order to optimize the delay due to both radio access and computation, under the long-term energy consumption constraint of the user. Based on Lyapunov optimization and multi-armed bandit theories, EMM works in an online fashion without future system state information, and effectively handles the imperfect system state information. Theoretical analysis explicitly takes radio handover and computation migration cost into consideration and proves a bounded deviation on both the delay performance and energy consumption compared with the oracle solution with exact and complete future system information. The proposed algorithm also effectively handles the scenario in which candidate BSs randomly switch ON/OFF during the offloading process of a task. Simulations show that the proposed algorithms can achieve close-to-optimal delay performance while satisfying the user energy consumption constraint.
将移动边缘计算(MEC)功能与密集部署的基站(BSs)相结合,可以带来巨大的好处,例如对计算资源的真正接近、低延迟访问。然而,设想的集成产生了许多新的挑战,其中移动性管理(MM)是一个关键的挑战。简单地应用现有的面向无线接入的MM方案会导致性能差,这主要是由于支持mec的BSs共同提供无线接入和计算服务。本文提出了一种新的以用户为中心的能量感知移动管理(EMM)方案,在用户长期能量消耗约束下,优化无线接入和计算的延迟。基于Lyapunov优化和多臂强盗理论,EMM在没有未来系统状态信息的情况下以在线方式工作,有效地处理了不完善的系统状态信息。理论分析明确考虑了无线电切换和计算迁移成本,证明了与具有准确完整的未来系统信息的oracle方案相比,该方案在延迟性能和能耗上都有一定的偏差。该算法还有效地处理了任务卸载过程中候选BSs随机开/关的情况。仿真结果表明,该算法在满足用户能量消耗约束的情况下,可以获得接近最优的延迟性能。
{"title":"EMM: Energy-Aware Mobility Management for Mobile Edge Computing in Ultra Dense Networks","authors":"Yuxuan Sun, Sheng Zhou, Jie Xu","doi":"10.1109/JSAC.2017.2760160","DOIUrl":"https://doi.org/10.1109/JSAC.2017.2760160","url":null,"abstract":"Merging mobile edge computing (MEC) functionality with the dense deployment of base stations (BSs) provides enormous benefits such as a real proximity, low latency access to computing resources. However, the envisioned integration creates many new challenges, among which mobility management (MM) is a critical one. Simply applying existing radio access-oriented MM schemes leads to poor performance mainly due to the co-provisioning of radio access and computing services of the MEC-enabled BSs. In this paper, we develop a novel user-centric energy-aware mobility management (EMM) scheme, in order to optimize the delay due to both radio access and computation, under the long-term energy consumption constraint of the user. Based on Lyapunov optimization and multi-armed bandit theories, EMM works in an online fashion without future system state information, and effectively handles the imperfect system state information. Theoretical analysis explicitly takes radio handover and computation migration cost into consideration and proves a bounded deviation on both the delay performance and energy consumption compared with the oracle solution with exact and complete future system information. The proposed algorithm also effectively handles the scenario in which candidate BSs randomly switch ON/OFF during the offloading process of a task. Simulations show that the proposed algorithms can achieve close-to-optimal delay performance while satisfying the user energy consumption constraint.","PeriodicalId":13243,"journal":{"name":"IEEE Journal on Selected Areas in Communications","volume":"35 1","pages":"2637-2646"},"PeriodicalIF":16.4,"publicationDate":"2017-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/JSAC.2017.2760160","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44969150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 307
Lysyl Oxidase Induces Vascular Oxidative Stress and Contributes to Arterial Stiffness and Abnormal Elastin Structure in Hypertension: Role of p38MAPK. 赖氨酰氧化酶诱发血管氧化应激并导致高血压患者动脉僵硬和弹性蛋白结构异常:p38MAPK 的作用。
IF 6.6 1区 计算机科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2017-09-01 Epub Date: 2017-01-30 DOI: 10.1089/ars.2016.6642
Sonia Martínez-Revelles, Ana B García-Redondo, María S Avendaño, Saray Varona, Teresa Palao, Mar Orriols, Fernanda R Roque, Ana Fortuño, Rhian M Touyz, Jose Martínez-González, Mercedes Salaices, Cristina Rodríguez, Ana M Briones

Aims: Vascular stiffness, structural elastin abnormalities, and increased oxidative stress are hallmarks of hypertension. Lysyl oxidase (LOX) is an elastin crosslinking enzyme that produces H2O2 as a by-product. We addressed the interplay between LOX, oxidative stress, vessel stiffness, and elastin.

Results: Angiotensin II (Ang II)-infused hypertensive mice and spontaneously hypertensive rats (SHR) showed increased vascular LOX expression and stiffness and an abnormal elastin structure. Mice over-expressing LOX in vascular smooth muscle cells (TgLOX) exhibited similar mechanical and elastin alterations to those of hypertensive models. LOX inhibition with β-aminopropionitrile (BAPN) attenuated mechanical and elastin alterations in TgLOX mice, Ang II-infused mice, and SHR. Arteries from TgLOX mice, Ang II-infused mice, and/or SHR exhibited increased vascular H2O2 and O2.- levels, NADPH oxidase activity, and/or mitochondrial dysfunction. BAPN prevented the higher oxidative stress in hypertensive models. Treatment of TgLOX and Ang II-infused mice and SHR with the mitochondrial-targeted superoxide dismutase mimetic mito-TEMPO, the antioxidant apocynin, or the H2O2 scavenger polyethylene glycol-conjugated catalase (PEG-catalase) reduced oxidative stress, vascular stiffness, and elastin alterations. Vascular p38 mitogen-activated protein kinase (p38MAPK) activation was increased in Ang II-infused and TgLOX mice and this effect was prevented by BAPN, mito-TEMPO, or PEG-catalase. SB203580, the p38MAPK inhibitor, normalized vessel stiffness and elastin structure in TgLOX mice.

Innovation: We identify LOX as a novel source of vascular reactive oxygen species and a new pathway involved in vascular stiffness and elastin remodeling in hypertension.

Conclusion: LOX up-regulation is associated with enhanced oxidative stress that promotes p38MAPK activation, elastin structural alterations, and vascular stiffness. This pathway contributes to vascular abnormalities in hypertension. Antioxid. Redox Signal. 27, 379-397.

目的:血管僵硬、弹性蛋白结构异常和氧化应激增加是高血压的特征。赖氨酰氧化酶(LOX)是一种弹性蛋白交联酶,会产生 H2O2 作为副产品。我们研究了 LOX、氧化应激、血管僵硬度和弹性蛋白之间的相互作用:结果:血管紧张素 II(Ang II)注射的高血压小鼠和自发性高血压大鼠(SHR)的血管 LOX 表达和僵硬度增加,弹性蛋白结构异常。在血管平滑肌细胞中过度表达 LOX 的小鼠(TgLOX)表现出与高血压模型相似的机械和弹性蛋白改变。用β-氨基丙腈(BAPN)抑制LOX可减轻TgLOX小鼠、血管紧张素II注射小鼠和SHR的机械和弹性蛋白改变。TgLOX 小鼠、血管紧张素 II 灌注小鼠和/或 SHR 的动脉表现出血管 H2O2 和 O2.- 水平升高、NADPH 氧化酶活性升高和/或线粒体功能障碍。BAPN 可防止高血压模型中氧化应激的增加。用线粒体靶向超氧化物歧化酶模拟物 mito-TEMPO、抗氧化剂 apocynin 或 H2O2 清除剂聚乙二醇结合过氧化氢酶(PEG-catalase)处理 TgLOX 和 Ang II 注入的小鼠和 SHR,可减少氧化应激、血管僵硬度和弹性蛋白的改变。血管p38丝裂原活化蛋白激酶(p38MAPK)的活化在血管紧张素II注射小鼠和TgLOX小鼠中有所增加,BAPN、丝裂原-TEMPO或PEG-过氧化氢酶可阻止这种效应。p38MAPK抑制剂SB203580可使TgLOX小鼠的血管硬度和弹性蛋白结构恢复正常:创新之处:我们发现 LOX 是血管活性氧的一个新来源,也是参与高血压血管僵化和弹性蛋白重塑的一个新途径:LOX上调与氧化应激增强有关,氧化应激可促进p38MAPK活化、弹性蛋白结构改变和血管僵化。这一途径导致了高血压的血管异常。抗氧化Redox Signal.27, 379-397.
{"title":"Lysyl Oxidase Induces Vascular Oxidative Stress and Contributes to Arterial Stiffness and Abnormal Elastin Structure in Hypertension: Role of p38MAPK.","authors":"Sonia Martínez-Revelles, Ana B García-Redondo, María S Avendaño, Saray Varona, Teresa Palao, Mar Orriols, Fernanda R Roque, Ana Fortuño, Rhian M Touyz, Jose Martínez-González, Mercedes Salaices, Cristina Rodríguez, Ana M Briones","doi":"10.1089/ars.2016.6642","DOIUrl":"10.1089/ars.2016.6642","url":null,"abstract":"<p><strong>Aims: </strong>Vascular stiffness, structural elastin abnormalities, and increased oxidative stress are hallmarks of hypertension. Lysyl oxidase (LOX) is an elastin crosslinking enzyme that produces H<sub>2</sub>O<sub>2</sub> as a by-product. We addressed the interplay between LOX, oxidative stress, vessel stiffness, and elastin.</p><p><strong>Results: </strong>Angiotensin II (Ang II)-infused hypertensive mice and spontaneously hypertensive rats (SHR) showed increased vascular LOX expression and stiffness and an abnormal elastin structure. Mice over-expressing LOX in vascular smooth muscle cells (TgLOX) exhibited similar mechanical and elastin alterations to those of hypertensive models. LOX inhibition with β-aminopropionitrile (BAPN) attenuated mechanical and elastin alterations in TgLOX mice, Ang II-infused mice, and SHR. Arteries from TgLOX mice, Ang II-infused mice, and/or SHR exhibited increased vascular H<sub>2</sub>O<sub>2</sub> and O<sub>2</sub><sup>.-</sup> levels, NADPH oxidase activity, and/or mitochondrial dysfunction. BAPN prevented the higher oxidative stress in hypertensive models. Treatment of TgLOX and Ang II-infused mice and SHR with the mitochondrial-targeted superoxide dismutase mimetic mito-TEMPO, the antioxidant apocynin, or the H<sub>2</sub>O<sub>2</sub> scavenger polyethylene glycol-conjugated catalase (PEG-catalase) reduced oxidative stress, vascular stiffness, and elastin alterations. Vascular p38 mitogen-activated protein kinase (p38MAPK) activation was increased in Ang II-infused and TgLOX mice and this effect was prevented by BAPN, mito-TEMPO, or PEG-catalase. SB203580, the p38MAPK inhibitor, normalized vessel stiffness and elastin structure in TgLOX mice.</p><p><strong>Innovation: </strong>We identify LOX as a novel source of vascular reactive oxygen species and a new pathway involved in vascular stiffness and elastin remodeling in hypertension.</p><p><strong>Conclusion: </strong>LOX up-regulation is associated with enhanced oxidative stress that promotes p38MAPK activation, elastin structural alterations, and vascular stiffness. This pathway contributes to vascular abnormalities in hypertension. Antioxid. Redox Signal. 27, 379-397.</p>","PeriodicalId":13243,"journal":{"name":"IEEE Journal on Selected Areas in Communications","volume":"27 1","pages":"379-397"},"PeriodicalIF":6.6,"publicationDate":"2017-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5563924/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84360353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Network Slicing for Service-Oriented Networks Under Resource Constraints 资源约束下面向服务网络的网络切片
IF 16.4 1区 计算机科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2017-08-24 DOI: 10.1109/JSAC.2017.2760147
N. Zhang, Ya-Feng Liu, H. Farmanbar, Tsung-Hui Chang, Mingyi Hong, Z. Luo
To support multiple on-demand services over fixed communication networks, network operators must allow flexible customization and fast provision of their network resources. One effective approach to this end is network virtualization, whereby each service is mapped to a virtual subnetwork providing dedicated on-demand support to network users. In practice, each service consists of a prespecified sequence of functions, called a service function chain (SFC), while each service function in a SFC can only be provided by some given network nodes. Thus, to support a given service, we must select network function nodes according to the SFC and determine the routing strategy through the function nodes in a specified order. A crucial network slicing problem that needs to be addressed is how to optimally localize the service functions in a physical network as specified by the SFCs, subject to link and node capacity constraints. In this paper, we formulate the network slicing problem as a mixed binary linear program and establish its strong NP-hardness. Furthermore, we propose efficient penalty successive upper bound minimization (PSUM) and PSUM-R(ounding) algorithms, and two heuristic algorithms to solve the problem. Simulation results are shown to demonstrate the effectiveness of the proposed algorithms.
为了支持固定通信网络上的多种按需服务,网络运营商必须允许灵活定制和快速提供其网络资源。实现这一目的的一种有效方法是网络虚拟化,即将每个服务映射到一个虚拟子网络,为网络用户提供专用的按需支持。在实践中,每个服务都由一个预先指定的功能序列组成,称为服务功能链(SFC),而SFC中的每个服务功能只能由一些给定的网络节点提供。因此,为了支持给定的服务,我们必须根据SFC选择网络功能节点,并按照指定的顺序确定通过功能节点的路由策略。需要解决的一个关键的网络切片问题是,如何根据链路和节点容量限制,在SFC指定的物理网络中优化定位服务功能。本文将网络切片问题表示为一个混合二元线性规划,并建立了它的强NP硬度。此外,我们提出了有效的惩罚连续上界最小化(PSUM)和PSUM-R(ounding)算法,以及两种启发式算法来解决这个问题。仿真结果证明了所提算法的有效性。
{"title":"Network Slicing for Service-Oriented Networks Under Resource Constraints","authors":"N. Zhang, Ya-Feng Liu, H. Farmanbar, Tsung-Hui Chang, Mingyi Hong, Z. Luo","doi":"10.1109/JSAC.2017.2760147","DOIUrl":"https://doi.org/10.1109/JSAC.2017.2760147","url":null,"abstract":"To support multiple on-demand services over fixed communication networks, network operators must allow flexible customization and fast provision of their network resources. One effective approach to this end is network virtualization, whereby each service is mapped to a virtual subnetwork providing dedicated on-demand support to network users. In practice, each service consists of a prespecified sequence of functions, called a service function chain (SFC), while each service function in a SFC can only be provided by some given network nodes. Thus, to support a given service, we must select network function nodes according to the SFC and determine the routing strategy through the function nodes in a specified order. A crucial network slicing problem that needs to be addressed is how to optimally localize the service functions in a physical network as specified by the SFCs, subject to link and node capacity constraints. In this paper, we formulate the network slicing problem as a mixed binary linear program and establish its strong NP-hardness. Furthermore, we propose efficient penalty successive upper bound minimization (PSUM) and PSUM-R(ounding) algorithms, and two heuristic algorithms to solve the problem. Simulation results are shown to demonstrate the effectiveness of the proposed algorithms.","PeriodicalId":13243,"journal":{"name":"IEEE Journal on Selected Areas in Communications","volume":"35 1","pages":"2512-2521"},"PeriodicalIF":16.4,"publicationDate":"2017-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1109/JSAC.2017.2760147","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41625135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 77
Jointly Optimal Routing and Caching for Arbitrary Network Topologies 任意网络拓扑的联合最优路由和缓存
IF 16.4 1区 计算机科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2017-08-20 DOI: 10.1145/3125719.3125730
Stratis Ioannidis, E. Yeh
We study a problem of minimizing routing costs by jointly optimizing caching and routing decisions over an arbitrary network topology. We cast this as an equivalent caching gain maximization problem, and consider both source routing and hop-by-hop routing settings. The respective offline problems are NP-hard. Nevertheless, we show that there exist polynomial time approximation algorithms producing solutions within a constant approximation from the optimal. We also produce distributed, adaptive algorithms with the same approximation guarantees. We simulate our adaptive algorithms over a broad array of different topologies. Our algorithms reduce routing costs by several orders of magnitude compared with prior art, including algorithms optimizing caching under fixed routing.
我们研究了在任意网络拓扑上通过联合优化缓存和路由决策来最小化路由开销的问题。我们将此转换为等价的缓存增益最大化问题,并同时考虑源路由和逐跳路由设置。各自的离线问题都是np困难的。然而,我们证明存在多项式时间近似算法,在最优的常数近似内产生解。我们还生产了具有相同近似保证的分布式自适应算法。我们在各种不同的拓扑结构上模拟我们的自适应算法。与现有技术相比,我们的算法将路由成本降低了几个数量级,包括在固定路由下优化缓存的算法。
{"title":"Jointly Optimal Routing and Caching for Arbitrary Network Topologies","authors":"Stratis Ioannidis, E. Yeh","doi":"10.1145/3125719.3125730","DOIUrl":"https://doi.org/10.1145/3125719.3125730","url":null,"abstract":"We study a problem of minimizing routing costs by jointly optimizing caching and routing decisions over an arbitrary network topology. We cast this as an equivalent caching gain maximization problem, and consider both source routing and hop-by-hop routing settings. The respective offline problems are NP-hard. Nevertheless, we show that there exist polynomial time approximation algorithms producing solutions within a constant approximation from the optimal. We also produce distributed, adaptive algorithms with the same approximation guarantees. We simulate our adaptive algorithms over a broad array of different topologies. Our algorithms reduce routing costs by several orders of magnitude compared with prior art, including algorithms optimizing caching under fixed routing.","PeriodicalId":13243,"journal":{"name":"IEEE Journal on Selected Areas in Communications","volume":"36 1","pages":"1258-1275"},"PeriodicalIF":16.4,"publicationDate":"2017-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1145/3125719.3125730","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43181517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 75
Proactive Retention-Aware Caching With Multi-Path Routing for Wireless Edge Networks 无线边缘网络多路径路由的主动保留感知缓存
IF 16.4 1区 计算机科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2017-07-10 DOI: 10.1145/3084041.3084053
Samta Shukla, Onkar Bhardwaj, A. Abouzeid, T. Salonidis, T. He
We consider the problem of proactive retention aware caching in a heterogeneous wireless edge network consisting of mobile users accessing content from a server and associated to one or more edge caches. Our goal is to design a caching policy that minimizes the sum of content storage costs and server access costs over two design variables: the retention time of each cached content and the probability that a user routes content requests to each of its associated caches. We develop a model that captures multiple aspects such as cache storage costs and several capabilities of modern wireless technologies, such as server multicast/unicast transmissions, device multi-path routing, and cache access constraints. We formulate the problem of Proactive Retention Routing Optimization as a non-convex, non-linear mixed-integer program. We prove that it is NP-hard under both multicast/unicast modes—even when the caches have a large capacity and storage costs are linear—and develop greedy algorithms that have provable performance bounds for the case of uncapacitated caches. Finally, we propose heuristics with low computational complexity for the capacitated cache case as well as for the case of convex storage costs. Systematic evaluations based on real-world data demonstrate the effectiveness of our approach, compared to the existing caching schemes.
我们考虑了异构无线边缘网络中的主动保留感知缓存问题,该网络由从服务器访问内容并与一个或多个边缘缓存相关联的移动用户组成。我们的目标是设计一种缓存策略,在两个设计变量中最大限度地减少内容存储成本和服务器访问成本之和:每个缓存内容的保留时间和用户将内容请求路由到每个相关缓存的概率。我们开发了一个模型,该模型涵盖了多个方面,如缓存存储成本和现代无线技术的几种功能,如服务器多播/单播传输、设备多路径路由和缓存访问限制。我们将主动保留路由优化问题表述为一个非凸非线性混合整数规划。我们证明了它在多播/单播模式下都是NP难的——即使缓存具有大容量且存储成本是线性的——并开发了贪婪算法,该算法在无容量缓存的情况下具有可证明的性能边界。最后,我们针对容量缓存情况以及凸存储成本的情况,提出了计算复杂度较低的启发式算法。与现有的缓存方案相比,基于真实世界数据的系统评估证明了我们的方法的有效性。
{"title":"Proactive Retention-Aware Caching With Multi-Path Routing for Wireless Edge Networks","authors":"Samta Shukla, Onkar Bhardwaj, A. Abouzeid, T. Salonidis, T. He","doi":"10.1145/3084041.3084053","DOIUrl":"https://doi.org/10.1145/3084041.3084053","url":null,"abstract":"We consider the problem of proactive retention aware caching in a heterogeneous wireless edge network consisting of mobile users accessing content from a server and associated to one or more edge caches. Our goal is to design a caching policy that minimizes the sum of content storage costs and server access costs over two design variables: the retention time of each cached content and the probability that a user routes content requests to each of its associated caches. We develop a model that captures multiple aspects such as cache storage costs and several capabilities of modern wireless technologies, such as server multicast/unicast transmissions, device multi-path routing, and cache access constraints. We formulate the problem of Proactive Retention Routing Optimization as a non-convex, non-linear mixed-integer program. We prove that it is NP-hard under both multicast/unicast modes—even when the caches have a large capacity and storage costs are linear—and develop greedy algorithms that have provable performance bounds for the case of uncapacitated caches. Finally, we propose heuristics with low computational complexity for the capacitated cache case as well as for the case of convex storage costs. Systematic evaluations based on real-world data demonstrate the effectiveness of our approach, compared to the existing caching schemes.","PeriodicalId":13243,"journal":{"name":"IEEE Journal on Selected Areas in Communications","volume":"36 1","pages":"1286-1299"},"PeriodicalIF":16.4,"publicationDate":"2017-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1145/3084041.3084053","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43747200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 30
期刊
IEEE Journal on Selected Areas in Communications
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1