首页 > 最新文献

Indian Journal of Otolaryngology and Head and Neck Surgery最新文献

英文 中文
The role of photobiomodulation therapy for supportive care during head and neck cancer treatment 光生物调节疗法在头颈癌治疗中的支持治疗作用
Q3 Medicine Pub Date : 2023-10-15 DOI: 10.18231/j.ijashnb.2023.022
Rajkumari P. Khatri
Radiotherapy and chemotherapy are frequently employed in patients with head and neck cancer (HNC), causing significant side effects that impair life quality and prognosis by interfering with the cancer treatment regimen. There is a large body of evidence supporting the efficacy of low-level laser therapy (LLLT), also known as Photobiomodulation (PBM), when used for the prevention and/or treatment of oral mucositis in patients undergoing radiotherapy for head and neck cancer or high-dose chemotherapy regimens. This could enhance patients’ quality of life, adherence to the prescribed cancer therapy, and treatment outcomes while reducing the cost of cancer care and hospitalization.
头颈癌(HNC)患者经常采用放疗和化疗,放疗和化疗会干扰癌症治疗方案,产生严重的副作用,影响生活质量和预后。有大量证据支持低水平激光治疗(LLLT),也称为光生物调节(PBM),用于预防和/或治疗头颈癌放疗或高剂量化疗方案患者的口腔黏膜炎的疗效。这可以提高患者的生活质量、对癌症治疗的依从性和治疗结果,同时降低癌症护理和住院费用。
{"title":"The role of photobiomodulation therapy for supportive care during head and neck cancer treatment","authors":"Rajkumari P. Khatri","doi":"10.18231/j.ijashnb.2023.022","DOIUrl":"https://doi.org/10.18231/j.ijashnb.2023.022","url":null,"abstract":"Radiotherapy and chemotherapy are frequently employed in patients with head and neck cancer (HNC), causing significant side effects that impair life quality and prognosis by interfering with the cancer treatment regimen. There is a large body of evidence supporting the efficacy of low-level laser therapy (LLLT), also known as Photobiomodulation (PBM), when used for the prevention and/or treatment of oral mucositis in patients undergoing radiotherapy for head and neck cancer or high-dose chemotherapy regimens. This could enhance patients’ quality of life, adherence to the prescribed cancer therapy, and treatment outcomes while reducing the cost of cancer care and hospitalization.","PeriodicalId":13287,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"234 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135760098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of adjuvant intravenous bevacizumab for aggressive recurrent respiratory papillomatosis- A case report 使用辅助静脉注射贝伐单抗治疗侵袭性复发性呼吸道乳头状瘤病1例报告
Q3 Medicine Pub Date : 2023-10-15 DOI: 10.18231/j.ijashnb.2023.019
Deepa Shivnani
Recurrent Respiratory Papillomatosis (RRP) is a benign condition which needs frequent surgical interventions for debulking of papillomatosis lesions for securing the airway. There is no definitive treatment for the management of RRP so far. Bevacizumab either intralesional or systemic has emerged as a promising solution for RRP patients undergoing repeated surgeries. We are reporting a case of a 6-year-old child with juvenile onset RRP who was treated by surgical excision of lesion with adjuvant systemic bevacizumab therapy.
复发性呼吸道乳头状瘤病(RRP)是一种良性疾病,需要经常进行手术治疗以减少乳头状瘤病变以保护气道。到目前为止,对于RRP的管理还没有明确的治疗方法。对于反复手术的RRP患者,贝伐单抗已经成为一种有希望的解决方案。我们报告一例6岁儿童儿童期发病RRP,手术切除病变并辅以全身贝伐单抗治疗。
{"title":"Use of adjuvant intravenous bevacizumab for aggressive recurrent respiratory papillomatosis- A case report","authors":"Deepa Shivnani","doi":"10.18231/j.ijashnb.2023.019","DOIUrl":"https://doi.org/10.18231/j.ijashnb.2023.019","url":null,"abstract":"Recurrent Respiratory Papillomatosis (RRP) is a benign condition which needs frequent surgical interventions for debulking of papillomatosis lesions for securing the airway. There is no definitive treatment for the management of RRP so far. Bevacizumab either intralesional or systemic has emerged as a promising solution for RRP patients undergoing repeated surgeries. We are reporting a case of a 6-year-old child with juvenile onset RRP who was treated by surgical excision of lesion with adjuvant systemic bevacizumab therapy.","PeriodicalId":13287,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"234 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occipital intracranial dural arteriovenous fistula with giant venous aneurysm and ruptured temporal arterial aneurysm with intra cerebral haemorrhage – a case report 枕骨硬脑膜内动静脉瘘合并巨静脉动脉瘤及颞动脉动脉瘤破裂并发脑出血1例
Q3 Medicine Pub Date : 2023-10-15 DOI: 10.18231/j.ijashnb.2023.016
S. Balaji, S. Venkatesan
As we all know 10% of all cerebral vascular anomalies are caused by a dural arteriovenous fistula (dAVF). While these lesions may be benign, the existence of retrograde venous drainage and cerebral venous reflux puts patients at risk of bleeding, neurological impairment, and death. Endovascular therapy is commonly utilized as the first-line treatment for dAVF. Both trans arterial and transvenous techniques are utilized to treat dAVF. The treatment strategy employed is dictated on the dAVF's angioarchitecture, location, and venous flow direction. Surgery and, to a lesser extent, stereotactic radiosurgery are used when endovascular procedures are ineffective or unsatisfactory, as well as when an AV fistula is associated with a ruptured aneurysm with cerebral bleeding.
我们都知道10%的脑血管异常是由硬脑膜动静脉瘘(dAVF)引起的。虽然这些病变可能是良性的,但存在逆行静脉引流和脑静脉反流会使患者面临出血、神经损伤和死亡的风险。血管内治疗通常作为dAVF的一线治疗方法。经动脉和经静脉技术均可用于治疗dAVF。所采用的治疗策略取决于dAVF的血管结构、位置和静脉流动方向。当血管内手术无效或不令人满意时,以及当房室瘘合并动脉瘤破裂并脑出血时,可以使用手术和立体定向放射手术(在较小程度上)。
{"title":"Occipital intracranial dural arteriovenous fistula with giant venous aneurysm and ruptured temporal arterial aneurysm with intra cerebral haemorrhage – a case report","authors":"S. Balaji, S. Venkatesan","doi":"10.18231/j.ijashnb.2023.016","DOIUrl":"https://doi.org/10.18231/j.ijashnb.2023.016","url":null,"abstract":"As we all know 10% of all cerebral vascular anomalies are caused by a dural arteriovenous fistula (dAVF). While these lesions may be benign, the existence of retrograde venous drainage and cerebral venous reflux puts patients at risk of bleeding, neurological impairment, and death. Endovascular therapy is commonly utilized as the first-line treatment for dAVF. Both trans arterial and transvenous techniques are utilized to treat dAVF. The treatment strategy employed is dictated on the dAVF's angioarchitecture, location, and venous flow direction. Surgery and, to a lesser extent, stereotactic radiosurgery are used when endovascular procedures are ineffective or unsatisfactory, as well as when an AV fistula is associated with a ruptured aneurysm with cerebral bleeding.","PeriodicalId":13287,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"21 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Importance of biopsychosocial model in Indian clinical physiotherapy practice 生物心理社会模型在印度临床物理治疗实践中的重要性
Q3 Medicine Pub Date : 2023-10-15 DOI: 10.18231/j.ijashnb.2023.023
Alagappan Thiyagarajan
The biopsychosocial model is one of the most important models in physiotherapy practice. It has been proven to be particularly useful in treating behaviorally regulated diseases that have a wide range of risk factors, such as type 2 diabetes mellitus, osteoarthritis, obesity, hypertension, and cardiac issues. Physiotherapists should be aware of their modes of action in terms of the cultural environment in which they operate and the unique needs of the patients in order to refocus Physiotherapy practice toward the whole treatment of patients without compromising professional ethics. The purpose of this paper is to provide an overview of physiotherapists' methods of action and to highlight the importance of incorporating models of disablement, the idea of rehabilitation, the biomedical model, and the biopsychosocial model into patient management strategies.
生物心理社会模型是物理治疗实践中最重要的模型之一。它已被证明在治疗具有广泛风险因素的行为调节疾病方面特别有用,如2型糖尿病、骨关节炎、肥胖、高血压和心脏问题。物理治疗师应该根据他们所处的文化环境和患者的独特需求来了解他们的行动模式,以便在不损害职业道德的情况下将物理治疗实践的重点重新放在患者的整体治疗上。本文的目的是概述物理治疗师的行动方法,并强调将残疾模型、康复理念、生物医学模型和生物心理社会模型纳入患者管理策略的重要性。
{"title":"Importance of biopsychosocial model in Indian clinical physiotherapy practice","authors":"Alagappan Thiyagarajan","doi":"10.18231/j.ijashnb.2023.023","DOIUrl":"https://doi.org/10.18231/j.ijashnb.2023.023","url":null,"abstract":"The biopsychosocial model is one of the most important models in physiotherapy practice. It has been proven to be particularly useful in treating behaviorally regulated diseases that have a wide range of risk factors, such as type 2 diabetes mellitus, osteoarthritis, obesity, hypertension, and cardiac issues. Physiotherapists should be aware of their modes of action in terms of the cultural environment in which they operate and the unique needs of the patients in order to refocus Physiotherapy practice toward the whole treatment of patients without compromising professional ethics. The purpose of this paper is to provide an overview of physiotherapists' methods of action and to highlight the importance of incorporating models of disablement, the idea of rehabilitation, the biomedical model, and the biopsychosocial model into patient management strategies.","PeriodicalId":13287,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"72 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135761321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A case report of transient ischemic attack with carotid artery stenosis and discussion on the need for carotid endarterectomy 短暂性脑缺血发作伴颈动脉狭窄1例并探讨颈动脉内膜切除术的必要性
Q3 Medicine Pub Date : 2023-10-15 DOI: 10.18231/j.ijashnb.2023.020
Premkumar Daivasikamani, Aung San Phyo
Carotid endarterectomy is common vascular procedure for atherosclerosis of carotid artery. Usually, it is done when the artery is narrowed more than 80% but it can be done even when it is narrowed 50 % if it produces symptoms. Carotid endarterectomy (CEA) is delayed 6 to 8 weeks after acute stoke, as the stroke can be progressive. Carotid endarterectomy (CEA) is done after optimal recovery from the stroke by the patient. The recovery depends on the preoperative size of the infarct and the neurological deficit. Emergency endarterectomy can be done when there is fluctuating neurological deficits due to acute carotid artery obstruction. CEA is contraindicated when the patient’s general condition is poor due to other serious illness which shorten life expectancy. It is not done in a case of major stroke as the recovery may not satisfactory.
颈动脉内膜切除术是治疗颈动脉粥样硬化的常用血管手术。通常,当动脉狭窄超过80%时进行手术,但如果出现症状,即使狭窄50%也可以进行手术。颈动脉内膜切除术(CEA)在急性中风后延迟6至8周,因为中风可能是进行性的。颈动脉内膜切除术(CEA)是在患者中风最佳恢复后进行的。恢复取决于术前梗塞的大小和神经功能缺损。当急性颈动脉阻塞引起波动性神经功能缺损时,可以进行紧急动脉内膜切除术。当患者因其他严重疾病导致一般情况较差,缩短预期寿命时,禁用CEA。在严重中风的情况下不这样做,因为恢复可能不令人满意。
{"title":"A case report of transient ischemic attack with carotid artery stenosis and discussion on the need for carotid endarterectomy","authors":"Premkumar Daivasikamani, Aung San Phyo","doi":"10.18231/j.ijashnb.2023.020","DOIUrl":"https://doi.org/10.18231/j.ijashnb.2023.020","url":null,"abstract":"Carotid endarterectomy is common vascular procedure for atherosclerosis of carotid artery. Usually, it is done when the artery is narrowed more than 80% but it can be done even when it is narrowed 50 % if it produces symptoms. Carotid endarterectomy (CEA) is delayed 6 to 8 weeks after acute stoke, as the stroke can be progressive. Carotid endarterectomy (CEA) is done after optimal recovery from the stroke by the patient. The recovery depends on the preoperative size of the infarct and the neurological deficit. Emergency endarterectomy can be done when there is fluctuating neurological deficits due to acute carotid artery obstruction. CEA is contraindicated when the patient’s general condition is poor due to other serious illness which shorten life expectancy. It is not done in a case of major stroke as the recovery may not satisfactory.","PeriodicalId":13287,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135759776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Giant interhemispheric arachnoid cyst – A rare case report 巨大半球间蛛网膜囊肿1例罕见报告
Q3 Medicine Pub Date : 2023-10-15 DOI: 10.18231/j.ijashnb.2023.021
S. Balaji, S. Venkatesan
IHACs (interhemispheric arachnoid cysts) are a rare kind of congenital arachnoid cyst that account for5% of all occurrences. The best surgical treatment for symptomatic IHAC is still debatable, and there are no clear standards. At the time of presentation, the median age was 13 months. Macrocrania with rapidly increasing head size, seizures, infantile spasms, and developmental delay were the most common clinical manifestations.Endoscopic cyst fenestration and shunt surgery are both safe treatments for IHAC. We present an 11-month-old male infant born to non consanguineous parents who has had a steady rise in head size since 6 months of age and delayed mile stones.A magnetic resonance image of the brain revealed a massive interhemispheric arachnoid cyst, as well as corpus callosum agenesis and hypoplasia in both frontal lobes. Baby underwent endoscopic cyst fenestration and cystoperitoneal shunt.
IHACs(半球间蛛网膜囊肿)是一种罕见的先天性蛛网膜囊肿,占所有病例的5%。对于症状性IHAC的最佳手术治疗仍有争议,也没有明确的标准。在就诊时,中位年龄为13个月。大颅畸形伴头部迅速增大、癫痫发作、婴儿痉挛和发育迟缓是最常见的临床表现。内窥镜囊肿开窗和分流手术都是IHAC的安全治疗方法。我们提出一个11个月大的男性婴儿出生的非近亲父母谁有稳定的头大小上升,自6个月的年龄和延迟结石。脑磁共振成像显示一个巨大的半球间蛛网膜囊肿,以及胼胝体发育不全和双额叶发育不全。婴儿接受了内窥镜囊肿开窗和膀胱腹腔分流术。
{"title":"Giant interhemispheric arachnoid cyst – A rare case report","authors":"S. Balaji, S. Venkatesan","doi":"10.18231/j.ijashnb.2023.021","DOIUrl":"https://doi.org/10.18231/j.ijashnb.2023.021","url":null,"abstract":"IHACs (interhemispheric arachnoid cysts) are a rare kind of congenital arachnoid cyst that account for5% of all occurrences. The best surgical treatment for symptomatic IHAC is still debatable, and there are no clear standards. At the time of presentation, the median age was 13 months. Macrocrania with rapidly increasing head size, seizures, infantile spasms, and developmental delay were the most common clinical manifestations.Endoscopic cyst fenestration and shunt surgery are both safe treatments for IHAC. We present an 11-month-old male infant born to non consanguineous parents who has had a steady rise in head size since 6 months of age and delayed mile stones.A magnetic resonance image of the brain revealed a massive interhemispheric arachnoid cyst, as well as corpus callosum agenesis and hypoplasia in both frontal lobes. Baby underwent endoscopic cyst fenestration and cystoperitoneal shunt.","PeriodicalId":13287,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"11 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135759780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuro radio logic diagnostic evaluation of partial seizure in children’s 儿童部分性癫痫的神经放射逻辑诊断评价
IF 0.6 Q3 Medicine Pub Date : 2023-08-15 DOI: 10.18231/j.ijashnb.2023.012
Tejanjani Vathada, Rajashekar Alishala
: Seizures are characterized by abnormally excessive or synchronized neuronal activity in the brain. The purpose of the current study is to study etiology of partial seizure. To identify significant role of neuroimaging & EEG.: A cross sectional study involving a total 100 patients are recruited between 2-12 years. All the children aged 2 year to 12 years of age with partial seizures will undergo neuro imaging, plain and contrast (contrast where indicated). Out of 100 childrens 68% of the partial seizures in the age group 2 to 12 years occurred in younger children of 2-6 Years, while only 32% of the seizures occurred in 6 – 12 years of age group.. Among them, 75% of the cases revealed an identifiable cause in the CT brain and 63% of the cases showed abnormal EEG. Among the 75% with abnormal CT brain, 58 cases are identified as Neuroinfections, neurocysticercosis in 32 cases, Tuberculoma in 26 cases, 5 cases had infarct, 4 had Calcifications, 3 had Hydrocephalus, 2 had subdural effusion, 2 had AV malformations, 1 had brain tumour. Thus, partial seizures are the most prevalent neurological disorder in children, having a significant social and economic impact on developing country.. Frequently, even relatively benign, episodic spells are mistaken as seizures and even treated as such. Therefore, proper diagnosis and therapy should be emphasized more.
癫痫发作的特征是大脑中异常过度或同步的神经元活动。本研究的目的是研究部分性癫痫发作的病因。确定神经影像学和脑电图的重要作用。:一项横断面研究,共招募了100名患者,时间为2-12年。所有2岁至12岁部分癫痫发作的儿童将接受神经影像学检查,包括普通和对比检查(如有指示,进行对比检查)。在100名儿童中,68%的2- 12岁年龄组部分性癫痫发作发生在2-6岁的幼儿中,而只有32%的癫痫发作发生在6 - 12岁年龄组。其中75%的病例在CT脑内显示出可识别的病因,63%的病例出现脑电图异常。在75%的脑CT异常中,神经感染58例,神经囊虫32例,结核瘤26例,梗死5例,钙化4例,脑积水3例,硬膜下积液2例,AV畸形2例,脑肿瘤1例。因此,部分性癫痫是儿童中最普遍的神经系统疾病,对发展中国家具有重大的社会和经济影响。通常,即使是相对良性的发作性发作也被误认为是癫痫发作,甚至被当作癫痫发作来治疗。因此,应更加重视正确的诊断和治疗。
{"title":"Neuro radio logic diagnostic evaluation of partial seizure in children’s","authors":"Tejanjani Vathada, Rajashekar Alishala","doi":"10.18231/j.ijashnb.2023.012","DOIUrl":"https://doi.org/10.18231/j.ijashnb.2023.012","url":null,"abstract":": Seizures are characterized by abnormally excessive or synchronized neuronal activity in the brain. The purpose of the current study is to study etiology of partial seizure. To identify significant role of neuroimaging & EEG.: A cross sectional study involving a total 100 patients are recruited between 2-12 years. All the children aged 2 year to 12 years of age with partial seizures will undergo neuro imaging, plain and contrast (contrast where indicated). Out of 100 childrens 68% of the partial seizures in the age group 2 to 12 years occurred in younger children of 2-6 Years, while only 32% of the seizures occurred in 6 – 12 years of age group.. Among them, 75% of the cases revealed an identifiable cause in the CT brain and 63% of the cases showed abnormal EEG. Among the 75% with abnormal CT brain, 58 cases are identified as Neuroinfections, neurocysticercosis in 32 cases, Tuberculoma in 26 cases, 5 cases had infarct, 4 had Calcifications, 3 had Hydrocephalus, 2 had subdural effusion, 2 had AV malformations, 1 had brain tumour. Thus, partial seizures are the most prevalent neurological disorder in children, having a significant social and economic impact on developing country.. Frequently, even relatively benign, episodic spells are mistaken as seizures and even treated as such. Therefore, proper diagnosis and therapy should be emphasized more.","PeriodicalId":13287,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"7 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82796456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Rare case of Multi-segment facial nerve schwannoma (MFNS) - A case report 面神经神经鞘瘤(MFNS) 1例
IF 0.6 Q3 Medicine Pub Date : 2023-08-15 DOI: 10.18231/j.ijashnb.2023.015
S. Balaji, S. Venkatesan
Multi-segment Facial Nerve Schwannoma (MFNS) is a very rare tumor, benign in nature and can arise anywhere along the course of the facial nerve from its origin in the cerebello-pontine angle to its extra cranial ramification in the parotid space of the extra cranial head and neck. It mimic like vestibular schwannoma and other cranial nerve schwannoma. The most common clinical presentation is facial palsy and depending upon the segment of the facial nerve involved. We report a rare case of multi-segment facial nerve schwannoma extending from cerebello-pontine angle to the parotid gland, presented with facial palsy, hearing loss, difficulty in swallowing and difficulty in walking. Radiological investigations was done and confirmed the diagnosis MFNS. Patient underwent near total excision of the tumor by combined approach and patient was improved clinically after the surgery.
多节段面神经神经鞘瘤(MFNS)是一种非常罕见的良性肿瘤,可发生于面神经从小脑-脑桥角的起源到颅外头颈部腮腺间隙的颅外分支的任何位置。它类似于前庭神经鞘瘤和其他脑神经神经鞘瘤。最常见的临床表现是面神经麻痹,这取决于面神经受累的部分。我们报告一例罕见的从小脑-脑桥角延伸到腮腺的多节段面神经鞘瘤,表现为面瘫、听力丧失、吞咽困难和行走困难。影像学检查证实了MFNS的诊断。患者经联合入路几乎完全切除肿瘤,术后临床改善。
{"title":"Rare case of Multi-segment facial nerve schwannoma (MFNS) - A case report","authors":"S. Balaji, S. Venkatesan","doi":"10.18231/j.ijashnb.2023.015","DOIUrl":"https://doi.org/10.18231/j.ijashnb.2023.015","url":null,"abstract":"Multi-segment Facial Nerve Schwannoma (MFNS) is a very rare tumor, benign in nature and can arise anywhere along the course of the facial nerve from its origin in the cerebello-pontine angle to its extra cranial ramification in the parotid space of the extra cranial head and neck. It mimic like vestibular schwannoma and other cranial nerve schwannoma. The most common clinical presentation is facial palsy and depending upon the segment of the facial nerve involved. We report a rare case of multi-segment facial nerve schwannoma extending from cerebello-pontine angle to the parotid gland, presented with facial palsy, hearing loss, difficulty in swallowing and difficulty in walking. Radiological investigations was done and confirmed the diagnosis MFNS. Patient underwent near total excision of the tumor by combined approach and patient was improved clinically after the surgery.","PeriodicalId":13287,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87827095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lymphocytopenia repercussions on stage III Non-small cell lung cancer (NSCLC) patients' tumour progression and their clinical results after chemoradiation 淋巴细胞减少对III期非小细胞肺癌(NSCLC)患者肿瘤进展的影响及其放化疗后的临床结果
IF 0.6 Q3 Medicine Pub Date : 2023-08-15 DOI: 10.18231/j.ijashnb.2023.010
Tshetiz Dahal, Dhiraj Prasad Shah, Aman Kumar Yadav
According to earlier research, tumour response, Lymphocytopenia, and a system-wide immune-inflammatory indexes all affect the clinical results of Stage III NSCLC. We postulated that the tumour response to CRT would be related to hematologic parameters and could perhaps anticipate clinical results.Retrospective evaluation of stage III NSCLC patients treated at a single facility between 2015 and 2020 was done. After receiving CRT, the pre-treatment gross tumour volume (GTV) was measured again. Full blood counts were taken before, during, and after treatment. Neutrophil platelet lymphocyte was used to define the systemic immune-inflammation index (SII). Kaplan-Meier estimates were used to compute overall survival (OS) and prognosis-free survival (PFS), which were then compared using Wilcoxon tests. Then, taking into account additional baseline parameters, pseudovalue regression was used to provide a multivariate study of hematopoietic factors affecting controlled average duration.There were 110 patients in total. The median PFS and OS were 20 and 35 months, respectively, after a median follow-up of 24 months. Baseline SII was correlated with OS (p = 0.039) but not PFS (p = 0.10), and baseline ALC was correlated with both PFS and OS (p = 0.13 and p = 0.06, respectively) in the multivariate model. The recovery SII, nadir ALC, and nadir SII were not connected to PFS or OS.: Baseline hematologic variables, such as baseline ALC, baseline SII, and recovery ALC, were related to clinical outcomes in this cohort of patients with stage III NSCLC. The relationship between disease response and hematologic variables or clinical outcomes was not strong.
根据早期的研究,肿瘤反应、淋巴细胞减少症和全系统免疫炎症指标都会影响III期NSCLC的临床结果。我们假设肿瘤对CRT的反应与血液学参数有关,并可能预测临床结果。回顾性评估了2015年至2020年间在单一机构治疗的III期NSCLC患者。接受CRT治疗后,再次测量治疗前总肿瘤体积(GTV)。在治疗前、治疗期间和治疗后分别进行全血细胞计数。用中性粒细胞血小板淋巴细胞定义全身免疫炎症指数(SII)。Kaplan-Meier估计用于计算总生存期(OS)和无预后生存期(PFS),然后使用Wilcoxon检验进行比较。然后,考虑到额外的基线参数,伪值回归被用于提供造血因素影响控制平均持续时间的多变量研究。共110例患者。中位随访24个月后,中位PFS和OS分别为20个月和35个月。在多变量模型中,基线SII与OS相关(p = 0.039),而与PFS无关(p = 0.10),基线ALC与PFS和OS均相关(p = 0.13和p = 0.06)。恢复SII、最低点ALC和最低点SII未连接到PFS或OS。基线血液学变量,如基线ALC、基线SII和恢复ALC,与该III期NSCLC患者队列的临床结果相关。疾病反应与血液学变量或临床结果的关系不强。
{"title":"Lymphocytopenia repercussions on stage III Non-small cell lung cancer (NSCLC) patients' tumour progression and their clinical results after chemoradiation","authors":"Tshetiz Dahal, Dhiraj Prasad Shah, Aman Kumar Yadav","doi":"10.18231/j.ijashnb.2023.010","DOIUrl":"https://doi.org/10.18231/j.ijashnb.2023.010","url":null,"abstract":"According to earlier research, tumour response, Lymphocytopenia, and a system-wide immune-inflammatory indexes all affect the clinical results of Stage III NSCLC. We postulated that the tumour response to CRT would be related to hematologic parameters and could perhaps anticipate clinical results.Retrospective evaluation of stage III NSCLC patients treated at a single facility between 2015 and 2020 was done. After receiving CRT, the pre-treatment gross tumour volume (GTV) was measured again. Full blood counts were taken before, during, and after treatment. Neutrophil platelet lymphocyte was used to define the systemic immune-inflammation index (SII). Kaplan-Meier estimates were used to compute overall survival (OS) and prognosis-free survival (PFS), which were then compared using Wilcoxon tests. Then, taking into account additional baseline parameters, pseudovalue regression was used to provide a multivariate study of hematopoietic factors affecting controlled average duration.There were 110 patients in total. The median PFS and OS were 20 and 35 months, respectively, after a median follow-up of 24 months. Baseline SII was correlated with OS (p = 0.039) but not PFS (p = 0.10), and baseline ALC was correlated with both PFS and OS (p = 0.13 and p = 0.06, respectively) in the multivariate model. The recovery SII, nadir ALC, and nadir SII were not connected to PFS or OS.: Baseline hematologic variables, such as baseline ALC, baseline SII, and recovery ALC, were related to clinical outcomes in this cohort of patients with stage III NSCLC. The relationship between disease response and hematologic variables or clinical outcomes was not strong.","PeriodicalId":13287,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"14 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80619457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparative study of hearing outcome in cholesteatoma surgery canal wall up versus canal wall downmastoidectomy in 100 patients 100例胆脂瘤手术上管壁与下管壁乳突切除术听力结果的比较研究
IF 0.6 Q3 Medicine Pub Date : 2023-08-15 DOI: 10.18231/j.ijashnb.2023.008
Trupti Savariya Rameshbhai, Alpesh Fefar Damjibhai
Cholesteatoma is a well-demarcated sac of keratinizing squamous epithelium in the temporal bone, which is commonly characterized as “skin in the wrong place. The major goal of surgery for cholesteatoma is to make the ear safe and dry with increasing concern of the hearing outcome of patients. Two main surgical techniques employed are Canal Wall down (CWD) and Canal Wall up Mastoidectomy (CWU). In the current study, an attempt would be made to evaluate which technique would be better for achieving disease clearance with favorable hearing outcome and dry ear.1. To evaluate the hearing results following CWU and CWD surgery in patient with cholesteatoma.2. To decide surgical approach according to extension of disease.Materials and Methods:This is a prospective study involving 100 patients with cholesteatoma who had undergone CWD and CWU surgery over the period of 3 years.The choice of mastoidectomy, CWD or CWU, was the decision of the surgeon, after completely evaluating the patient, preoperatively and intraoperatively. All cases were followed up & assessed by autoscopic examination & PTA for minimum of 3 months. In the CWD group, mean hearing gain, in 3 months was 12±1.73dB. In the CWU group, hearing gain in 3 month postoperative period was 18±2.06 dB. Also the hearing gain between the two groups was compared and it was found to be statistically significant for the 3 months (p=0.0002) postoperatively; signifying that there was a comparable difference for CWU over CWD mastoidectomy in the matter of Hearing Gain. SNHL was also seen post operatively in both group. Total 3 (6%) patient in CWU had SNHL post operatively in comparison to 7(14%) patients in CWD. From our study results, we think that CWU is superior to the CWD surgery in cases of cholesteatoma because of good post-operative hearing outcome as well as less complication and law morbidity. CWD surgery should be used in cases of extensive cholesteatoma, mental retardation, not sure about follow up and inadequate middle ear space cases.
胆脂瘤是颞骨内一种角化鳞状上皮囊状组织,通常表现为“皮肤错位”。胆脂瘤手术治疗的主要目标是使患者的耳部安全和干燥,同时也越来越关注患者的听力结果。两种主要的手术技术是乳突根治术(CWD)和乳突根治术(CWU)。在目前的研究中,我们将尝试评估哪种技术能够更好地实现疾病清除,同时获得良好的听力结果和干耳。目的:评价胆脂瘤患者行CWU和CWD手术后的听力效果。根据病情扩展情况确定手术入路。材料和方法:这是一项前瞻性研究,涉及100例接受CWD和CWU手术的胆脂瘤患者,为期3年。乳突切除术的选择,CWD或CWU,是外科医生在术前和术中对患者进行全面评估后的决定。所有病例均进行了至少3个月的自视检查和PTA随访和评估。CWD组3个月平均听力增加12±1.73dB。CWU组术后3个月听力增加18±2.06 dB。两组术后3个月的听力增益比较,差异均有统计学意义(p=0.0002);这表明CWU与CWD乳突切除术在听力增加方面有可比性差异。两组术后均出现SNHL。CWU患者术后SNHL发生率为3例(6%),CWD患者术后SNHL发生率为7例(14%)。从我们的研究结果来看,我们认为在胆脂瘤病例中,CWU手术优于CWD手术,因为CWU术后听力效果好,并发症少,发病率低。胆脂瘤广泛、智力低下、随访不确定、中耳空间不足的病例应采用CWD手术。
{"title":"A comparative study of hearing outcome in cholesteatoma surgery canal wall up versus canal wall downmastoidectomy in 100 patients","authors":"Trupti Savariya Rameshbhai, Alpesh Fefar Damjibhai","doi":"10.18231/j.ijashnb.2023.008","DOIUrl":"https://doi.org/10.18231/j.ijashnb.2023.008","url":null,"abstract":"Cholesteatoma is a well-demarcated sac of keratinizing squamous epithelium in the temporal bone, which is commonly characterized as “skin in the wrong place. The major goal of surgery for cholesteatoma is to make the ear safe and dry with increasing concern of the hearing outcome of patients. Two main surgical techniques employed are Canal Wall down (CWD) and Canal Wall up Mastoidectomy (CWU). In the current study, an attempt would be made to evaluate which technique would be better for achieving disease clearance with favorable hearing outcome and dry ear.1. To evaluate the hearing results following CWU and CWD surgery in patient with cholesteatoma.2. To decide surgical approach according to extension of disease.Materials and Methods:This is a prospective study involving 100 patients with cholesteatoma who had undergone CWD and CWU surgery over the period of 3 years.The choice of mastoidectomy, CWD or CWU, was the decision of the surgeon, after completely evaluating the patient, preoperatively and intraoperatively. All cases were followed up & assessed by autoscopic examination & PTA for minimum of 3 months. In the CWD group, mean hearing gain, in 3 months was 12±1.73dB. In the CWU group, hearing gain in 3 month postoperative period was 18±2.06 dB. Also the hearing gain between the two groups was compared and it was found to be statistically significant for the 3 months (p=0.0002) postoperatively; signifying that there was a comparable difference for CWU over CWD mastoidectomy in the matter of Hearing Gain. SNHL was also seen post operatively in both group. Total 3 (6%) patient in CWU had SNHL post operatively in comparison to 7(14%) patients in CWD. From our study results, we think that CWU is superior to the CWD surgery in cases of cholesteatoma because of good post-operative hearing outcome as well as less complication and law morbidity. CWD surgery should be used in cases of extensive cholesteatoma, mental retardation, not sure about follow up and inadequate middle ear space cases.","PeriodicalId":13287,"journal":{"name":"Indian Journal of Otolaryngology and Head and Neck Surgery","volume":"14 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85495032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Indian Journal of Otolaryngology and Head and Neck Surgery
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1